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2025
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Invention
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Crystalline form of (r)-1-(3-(3-(4-aminopyrimidin-2-yl)-5-chlorophenyl)morpholino)prop-2-en-1-one... |
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Invention
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Method for catalytically synthesizing single chiral 2-aryl-substituted nitrogen heterocyclic deri... |
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2024
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P/S
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Pharmaceutical products for the treatment of cancer Providing a website featuring blogs and non-d... |
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P/S
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Pharmaceutical products for the treatment of cancer and immune disorders Providing a website feat... |
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Invention
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Ras-pi3k inhibitors and uses thereof. Compounds of formula (I) and methods for modulating RAS-PI3K. |
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Invention
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Ras-pi3k inhibitors for the treatment of cancer and immunological diseases. The application relat... |
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Invention
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(e)-2-(benzylamino)-n-(3-(methylsulfonyl)allyl)-benzamide derivatives and similar compounds as ja... |
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Invention
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Keap1 inhibitors and uses thereof.
Compounds and methods for activating Nrf2 by inhibiting KEAP1. |
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Invention
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Keap1 inhibitors for use in the treatment of immunological disorders. Compounds and methods for a... |
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Invention
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Compounds and methods for modulating stat3.
Compounds and methods for inhibiting STAT3. |
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Invention
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2-azaspiro[3.3]heptane derivatives as stat3 inhibitors for the treatment of cancer. The present i... |
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Invention
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Compounds and methods for modulating ras-pi3k.
Compounds and methods for modulating RAS-PI3K. |
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Invention
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Compounds and methods for modulating ras-pi3k. Compounds and methods for modulating RAS-PI3K. |
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Invention
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1-(([1, 1',-biphenyl]-2-yl)sulfonyl)-4-fluoro-n-(3-(methylsulfonyl)allyl)piperidine-4-carboxamide... |
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2023
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Invention
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Inhibitors and uses thereof.
Compounds and methods for inhibiting Nrf2 by activating KEAP1. |
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Invention
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N-acryloylmorpholine derivatives as keap1 modulators and uses thereof. Compounds and methods for ... |
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Invention
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N-acryloylmorpholine derivatives as keap1 modulators and uses thereof |
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Invention
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Pharmaceutical compositions comprising wrn helicase inhibitors. Disclosed are compounds of Formul... |
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Invention
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Pharmaceutical compositions comprising wrn helicase inhibitors.
Disclosed are compounds of Formu... |
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Invention
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Pharmaceutical compositions comprising wrn helicase inhibitors |
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2022
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Invention
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Compounds selective for jak1 and methods of use.
Disclosed herein are compounds selective for JA... |
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Invention
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Compounds selective for jak1 and methods of use. Disclosed herein are compounds selective for JAK... |
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Invention
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In vivo engineered cereblon protein.
Disclosed herein are in vivo engineered cereblon protein an... |
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2021
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P/S
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Drug discovery services; pharmaceutical drug development services; pharmaceutical research and de... |
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P/S
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Drug discovery services; Pharmaceutical drug development services; Pharmaceutical research and de... |
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2020
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Invention
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Cereblon modulators and uses thereof. Disclosed herein are compositions and methods for modulatin... |
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Invention
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Compounds and methods for modulating immune-related proteins.
Disclosed herein are methods, phar... |
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Invention
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Compounds and methods for modulating immune-related proteins. Disclosed herein are methods, pharm... |
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2019
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Invention
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Substituted isoindolinones as modulators of cereblon-mediated neo-substrate recruitment.
Disclos... |
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Invention
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Substituted isoindolinones as modulators of cereblon-mediated neo-substrate recruitment. Disclose... |
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Invention
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In vivo engineered cereblon protein. Disclosed herein are in vivo engineered cereblon protein and... |
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2018
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Invention
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Compounds and methods of modulating protein degradation.
Disclosed herein are protein-probe addu... |
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Invention
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Compounds and methods of modulating protein degradation. Disclosed herein are protein-probe adduc... |