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2025
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Invention
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Morphic forms of a mutant braf degrader and methods of manufacture thereof.
Advantageous isolate... |
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Invention
|
Isoindolinone and indazole compounds for the degradation of egfr.
The invention provides compoun... |
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|
Invention
|
Spirocyclic compounds.
The present invention provides compounds which bind to the ubiquitously e... |
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2024
|
Invention
|
Therapeutics for the degradation of mutant braf.
The present invention provides compounds or the... |
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|
Invention
|
Compounds for the targeted degradation of smarca2.
The invention provides a bifunctional compoun... |
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Invention
|
N/o-linked degrons and degronimers for protein degradation. This invention provides Degronimers t... |
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Invention
|
Bicyclic-substituted glutarimide cereblon binders. This invention provides Degron compounds which... |
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|
Invention
|
Compounds for targeted degradation of brd9.
BRD9 protein degradation compounds or pharmaceutical... |
|
|
Invention
|
Dihydroquinolinones for medical treatment.
The present invention provides dihydroquinolinone com... |
|
|
Invention
|
Morphic forms of cft7455 and methods of manufacture thereof.
An advantageous morphic form of Com... |
|
|
Invention
|
Heterocyclic degronimers for target protein degradation.
This invention provides heterocyclic co... |
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|
Invention
|
Substituted piperidine degronimers for target protein degradation.
This invention provides amine... |
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|
Invention
|
Spirocyclic degronimers for target protein degradation.
This invention provides compounds that h... |
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|
Invention
|
C3-carbon linked glutarimide degronimers for target protein degradation.
This invention provides... |
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|
Invention
|
Selected compounds for targeted degradation of brd9.
Selected BRD9 protein degradation compounds... |
|
2023
|
Invention
|
Egfr degraders to treat cancer metastasis to the brain or cns.
The invention provides for the tr... |
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|
Invention
|
Glutarimides for medical treatment.
The present invention provides selected glutarimides which b... |
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|
Invention
|
Dihydrobenzimidazolones for medical treatment. The present invention provides selected dihydroben... |
|
|
Invention
|
Isoindolinone and indazole compounds for the degradation of egfr. The invention provides compound... |
|
|
Invention
|
Tricyclic heterobifunctional compounds for degradation of targeted proteins.
Heterobifunctional ... |
|
|
Invention
|
Tricyclic ligands for degradation of ikzf2 or ikzf4.
Tricyclic compounds that degrade IKZF2 and/... |
|
|
Invention
|
Spirocyclic compounds.
The present invention provides compounds and intermediates. The present i... |
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|
Invention
|
Advantageous therapies for disorders mediated by ikaros or aiolos.
New treatments for Ikaros and... |
|
|
Invention
|
Compounds for targeted degradation of ret.
Novel compounds which act as protein degradation indu... |
|
2022
|
Invention
|
Braf degraders.
Present invention provides compounds that cause specifically the degradation of ... |
|
|
Invention
|
Degraders and degrons for targeted protein degradation.
Pharmaceutical Degraders and Degrons for... |
|
|
Invention
|
Compounds for targeted degradation of brd9. BRD9 protein degradation compounds or pharmaceuticall... |
|
|
Invention
|
Dihydroquinolinones for medical treatment. The present invention provides dihydroquinolinone comp... |
|
|
Invention
|
Compounds for targeting degradation of irak4 proteins.
This disclosure relates to compounds of F... |
|
|
Invention
|
Compounds for targeting degradation of bruton's tyrosine kinase.
This disclosure relates to comp... |
|
|
Invention
|
Tricyclic degraders of ikaros and aiolos.
Tricyclic cereblon binders for the degradation of Ikar... |
|
2021
|
Invention
|
Compounds for targeted degradation of brd9. A BRD9 protein degrading compound of structure
or a... |
|
|
Invention
|
Spirocyclic degronimers for target protein degradation. This invention provides compounds that ha... |
|
|
Invention
|
Tricyclic degraders of ikaros and aiolos. Tricyclic cereblon binders for the degradation of Ikaro... |
|
|
Invention
|
Heterocyclic compounds for medical treatment.
The present invention provides heterocyclic compou... |
|
|
Invention
|
Targeted protein degradation. This invention provides pharmaceutical protein degraders and E3 ubi... |
|
|
Invention
|
Compounds for the degradation of brd9 or mth1.
Compounds that degrade BRD9 or MTH1 via the ubiqu... |
|
|
Invention
|
Heterocyclic degronimers for target protein degradation. This invention provides heterocyclic com... |
|
2020
|
Invention
|
Substituted piperidine degronimers for target protein degradation. 3-glutarimide Degronimers have... |
|
|
Invention
|
3-carbon linked glutarimide degronimers for target protein degradation. This invention provides D... |
|
|
Invention
|
Spirocyclic compounds. The present invention provides compounds and intermediates. The present in... |
|
|
Invention
|
Bifunctional compounds for the treatment of cancer.
The invention provides bifunctional compound... |
|
|
Invention
|
Bifunctional compounds.
The invention provides a bifunctional compound of formula (I), or a phar... |
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|
Invention
|
Degraders and degrons for targeted protein degradation. Pharmaceutical Degraders and Degrons for ... |
