Institut National de la Recherche Agronomique (France)
Inventeur(s)
Pibarot, Patrick
Schmitt, Christophe Jospeh Etienne
Sanchez, Christian
Morel, Marie-Hélène
Abrégé
A meat analogue may include a macrostructure of connected sheared fibers oriented parallel to one another and gaps positioned between the sheared fibers. The macrostructure may include meat and may include a vegetable protein. An extrusion system may include an extruder and a die. The extrusion system may produce a meat analogue. A meat analogue may include an animal protein. The extruder may be connectable to the die. The extrusion system may be configured to direct a material including an animal protein from the extruder to the die and through a fluid path extending through the die. The die may be configured to inject a fat or a fat analogue into the material such that the fat or the fat analogue is embedded but visually distinct from the material including the animal protein when the fat or the fat analogue and the material exit the die.
CENTRE NATIONAL DEL LA RECHERCH SCIENTIFIQUE (CNRS) (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMQIUE (France)
Inventeur(s)
Cerutti, Martine
Juliant, Sylvie
Thery, Sylvie
Abrégé
The invention relates to a method for producing a recombinant baculovirus comprising n exogenous genes in an insect cell, by means of homologous recombination of a replication-deficient baculovirus genome and n transfer vectors, each comprising one of the n exogenous genes, n being an integer at least equal to 2.
INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Geelen, Danny
Evon, Philippe
Cammue, Bruno
Haesaert, Geert
Kyndt, Tina
Werbrouck, Stefaan
Abrégé
The present invention relates to plant extracts and their use as biostimulant and biocontrol agent. More specific, the invention provides extracts of plants of the genus Helianthus which are capable of modifying root architecture and stimulate root development in plants. Hence, said extracts can be used to control plant development such as e.g. improve general root architecture, nutrient uptake and increase tolerance of plants to drought. In addition, these extracts can be used to control plant disease.
A01N 65/12 - Asteraceae ou Compositae [famille de l'aster ou du tournesol], p. ex. marguerite, pyrèthre, artichaut, laitue, tournesol, armoise ou estragon
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Veillet, Stanislas
Lafont, René
Foucault, Anne-Sophie
Dioh, Waly
Quignard-Boulange, Annie
Abrégé
A method of improving or maintaining muscle strength of aging muscle tissue. The muscle triglyceride content is decreased to improve or maintain muscle strength of a sarcopenic mammal by administering 20-hydroxyecdysone to said mammal.
A61K 31/575 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes substitués en position 17 bêta par une chaîne d'au moins trois atomes de carbone, p. ex. cholane, cholestane, ergostérol, sitostérol
A61K 36/21 - Amaranthaceae (famille de l'amaranthe), p. ex. amaranthe réfléchie ou amarantine globuleuse
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
Institut National de la Recherche Agronomique (France)
Inventeur(s)
Slezack-Deschaumes, Sophie
Piutti, Séverine
L'Yvonnet, Pierre
Roselli, Sandro
Abrégé
The present invention relates to the field of crop fertilization, and particularly to a biofertilizing bacterial strain. In particular, the present invention relates to the bacterial strain deposited on Oct. 24, 2018, at the Collection Nationale de Culture de Microorganismes (CNCM), 28 rue du Dr. Roux, 75724 PARIS CEDEX 15, under the Budapest Treaty under number CNCM I-5372, and to the uses of this strain. The invention also relates to a composition comprising the above-mentioned bacterial strain and to a fertilization process comprising the application of this composition to a plant or to a soil.
Institut National de la Recherche Agronomique (France)
Inventeur(s)
Slezack-Deschaumes, Sophie
Piutti, Séverine
L'Yvonnet, Pierre
Roselli, Sandro
Abrégé
The present invention relates to the field of crop fertilization, and particularly to a biofertilizing bacterial strain. In particular, the present invention relates to the bacterial strain deposited on Oct. 24, 2018, at the Collection Nationale de Culture de Microorganismes (CNCM), 28 rue du Dr. Roux, 75724 PARIS CEDEX 15, under the Budapest Treaty under number CNCM I-5373, and to the uses of this strain. The invention also relates to a composition comprising the above-mentioned bacterial strain and to a fertilization process comprising the application of this composition to a plant or to a soil.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
MUSEUM NATIONAL D'HISTOIRE NATURELLE (France)
ECOLE NATIONALE VETERINAIRE D'ALFORT (France)
Inventeur(s)
Bermudez-Humaran, Luis G.
Allain, Thibault
Florent, Isabelle
Langella, Philippe
Grellier, Philippe
Travers, Marie-Agnes
Polack, Bruno
Abrégé
The present invention relates to a composition exhibiting a bile-salt hydrolase activity for its use for the treatment or the prevention of giardiasis, said composition comprising a bile-salt hydrolase (BSH) enzyme, a bacterium able to secrete a BSH, a recombinant host cell able to secrete a BSH, or a combination thereof. The present invention also relates to the use of a composition exhibiting a BSH activity for the treatment or the prevention of giardiasis, and to a pharmaceutical composition or a food composition comprising, as an active principle, a BSH, a lactic acid bacterium able to secrete a BSH, or a recombinant host cell able to secrete a BSH.
A61K 38/50 - Hydrolases (3) agissant sur des liaisons carbone-azote autres que des liaisons peptidiques (3.5), p. ex. asparaginase
A23L 33/135 - Bactéries ou leurs dérivés, p. ex. probiotiques
C12N 9/80 - Hydrolases (3.) agissant sur les liaisons carbone-azote autres que les liaisons peptidiques (3.5) agissant sur les liaisons amides des amides aliphatiques
A61K 38/00 - Préparations médicinales contenant des peptides
A61K 38/16 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
A61K 35/744 - Bactéries lactiques, p. ex. entérocoques, pédiocoques, lactocoques, streptocoques ou leuconostoques
G01D 5/24 - Moyens mécaniques pour le transfert de la grandeur de sortie d'un organe sensibleMoyens pour convertir la grandeur de sortie d'un organe sensible en une autre variable, lorsque la forme ou la nature de l'organe sensible n'imposent pas un moyen de conversion déterminéTransducteurs non spécialement adaptés à une variable particulière utilisant des moyens électriques ou magnétiques influençant la valeur d'un courant ou d'une tension en faisant varier la capacité
H03K 17/955 - Commutateurs de proximité utilisant un détecteur capacitif
INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Geelen, Danny
Evon, Philippe
Cammue, Bruno
Haesaert, Geert
Kyndt, Tina
Werbrouck, Stefaan
Abrégé
HelianthusHelianthus which are capable of modifying root architecture and stimulate root development in plants. Hence, said extracts can be used to control plant development such as e.g. improve general root architecture, nutrient uptake and increase tolerance of plants to drought. In addition, these extracts can be used to control plant disease.
A01N 65/12 - Asteraceae ou Compositae [famille de l'aster ou du tournesol], p. ex. marguerite, pyrèthre, artichaut, laitue, tournesol, armoise ou estragon
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
ECOLE NATIONAL SUPERIEURE DES MINES D'ALBI-CARMAUX (France)
OVALIE INNOVATION (France)
Inventeur(s)
Kerfai, Syrine
Reboul, Bernard
Alfenore, Sandrine
Resende De Azevedo, Jacqueline
Fernandez, Maria Aurora
Mathe, Stephane
Usta, Maria Angelica
Re, Maria-Ines
Montaner, Manon
Abrégé
The invention relates to a process for producing ribulose-1,5-bisphosphate carboxylase/oxygenase, also called Rubisco, from a plant biomass, said process comprising in particular a step of chromatographic separation of Rubisco on an ion exchange resin.
A23J 1/14 - Préparation des compositions à base de protéines pour l'alimentationOuverture des œufs par grandes quantités et séparation du jaune du blanc à partir de légumineuses ou autres graines végétalesPréparation des compositions à base de protéines pour l'alimentationOuverture des œufs par grandes quantités et séparation du jaune du blanc à partir des tourteaux ou des graines oléagineuses
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Pibarot, Patrick
Schmitt, Christophe Joseph Etienne
Morel, Marie-Héléne
Sanchez, Christian
Abrégé
A meat analogue may include a macrostructure of connected sheared fibers oriented parallel to one another and gaps positioned between the sheared fibers. The macrostructure may include meat and may include a vegetable protein. An extrusion system may include an extruder and a die. The extrusion system may produce a meat analogue. A meat analogue may include an animal protein. The extruder may be connectable to the die. The extrusion system may be configured to direct a material including an animal protein from the extruder to the die and through a fluid path extending through the die. The die may be configured to inject a fat or a fat analogue into the material such that the fat or the fat analogue is embedded but visually distinct from the material including the animal protein when the fat or the fat analogue and the material exit the die.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Pibarot, Patrick
Schmitt, Christophe Joseph Etienne
Sanchez, Christian
Morel, Marie-Héléne
Abrégé
A meat analogue may include a macrostructure of connected sheared fibers oriented parallel to one another and gaps positioned between the sheared fibers. The macrostructure may include meat and may include a vegetable protein. An extrusion system may include an extruder and a die. The extrusion system may produce a meat analogue. A meat analogue may include an animal protein. The extruder may be connectable to the die. The extrusion system may be configured to direct a material including an animal protein from the extruder to the die and through a fluid path extending through the die. The die may be configured to inject a fat or a fat analogue into the material such that the fat or the fat analogue is embedded but visually distinct from the material including the animal protein when the fat or the fat analogue and the material exit the die.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
UNIVERSITÉ DE MONTPELLIER (France)
Inventeur(s)
Pibarot, Patrick
Morel, Marie-Héléne
Sanchez, Christian
Abrégé
A meat analogue may include a set protein emulsion, the protein emulsion having a protein and at least one insoluble particle. In some embodiments, at least a portion of the particle can include at least one mineral material selected from the group consisting of silicium, and calcium, such as one or more of rhombohedral calcite, scalenohedral calcite, silicon dioxide, and magnesium oxide; at least one organic material selected from the group consisting of a bone meal, a cartilage meal, a ground crustacean shell, a ground sea fish shell, and a ground egg shell; and/or a gelled vegetable gum, a gelled hydrocolloid, a polymerized vegetable gum, a polymerized hydrocolloid, or a mixture thereof. The meat analogue can be made by extruding the protein emulsion and cooling the extruded emulsion. The meat analogue can be cut into chunks and/or added to another comestible composition such as a gravy or broth.
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Bessiere, Yolaine
Paul, Etienne
Louvet, Jean-Noël
Blanchet, Elise
Mengelle, Evrard
Dubos, Simon
Bounouba, Mansour
Saux, Carine
Morgado Ferreira, Ana
Cirne, Dores
Abrégé
The invention relates to microbial cellular biomass having flocculant properties, to a method for producing same, and to the use thereof in flocculation treatment.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Aymard, Caroline
Louesdon, Severine
Rousset, Romain
Hudebine, Damien
Abrégé
The aim of the invention is a method for treating lignocellulosic biomass comprising the following steps: a) conditioning the lignocellulosic biomass; b) washing said particles; c) separating the aqueous solution from the washed biomass particles; d) impregnating said lignocellulosic substrate with an acid liquor; e) undertaking solid/liquid separation of the impregnated lignocellulosic substrate; f) pretreating said substrate originating from step e) by cooking; g) completing an enzymatic hydrolysis of the pretreated lignocellulosic substrate; h) fermenting the hydrolysat originating from step g); and - introducing the used aqueous washing solution into a step of said method for treating the biomass following the pretreating step f), and/or into a step of producing enzymes, and/or into a step of producing/propagating microorganisms that are needed in steps g) or h).
C12P 7/10 - Éthanol en tant que produit chimique et non en tant que boisson alcoolique préparé comme sous-produit, ou préparé à partir d'un substrat constitué par des déchets ou par des matières cellulosiques d'un substrat constitué par des matières cellulosiques
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
AGRO INDUSTRIES RECHERCHE ET DEVELOPPEMENT (France)
Inventeur(s)
Bouras Galinie, Meriem
Aymard, Caroline
Carnnot, Olivier
Abrégé
The present invention concerns a method for cleaning a reactor (4) for processing a lignocellulosic biomass (P), the method comprising the following steps: a) draining the reactor of the reaction medium containing the biomass, b) filling the reactor with a basic aqueous solution (EB), c) draining the reactor, d) injecting steam (V) into the reactor, e) filling the reactor with an aqueous solution (E), and f) draining the reactor.
C12P 7/10 - Éthanol en tant que produit chimique et non en tant que boisson alcoolique préparé comme sous-produit, ou préparé à partir d'un substrat constitué par des déchets ou par des matières cellulosiques d'un substrat constitué par des matières cellulosiques
C12P 19/14 - Préparation de composés contenant des radicaux saccharide préparés par action d'une carbohydrase, p. ex. par action de l'alpha-amylase
B08B 3/08 - Nettoyage impliquant le contact avec un liquide le liquide ayant un effet chimique ou dissolvant
B08B 9/08 - Nettoyage de récipients, p. ex. de réservoirs
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Slezack-Deschaumes, Sophie
Piutti, Séverine
L'Yvonnet, Pierre
Roselli, Sandro
Abrégé
The present invention relates to the field of crop fertilisation, and particularly to a biofertilising bacterial strain. The present invention relates, in particular, to the bacterial strain filed on 24 October 2018 at the Collection Nationale de Culture de Micro-organismes (CNCM), 28 rue du Dr. Roux, 75724 PARIS CEDEX 15, France, by virtue of the Treaty of Budapest, under number CNCM I-5373, and to the uses of this strain. The invention also relates to a composition comprising the bacterial strain mentioned above and to a fertilisation method comprising the application of this composition to a plant or to soil.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Slezack-Deschaumes, Sophie
Piutti, Séverine
L'Yvonnet, Pierre
Roselli, Sandro
Abrégé
The present invention relates to the field of crop fertilization and particularly to a biofertilizing bacterial strain. The present invention relates in particular to the bacterial strain deposited on 24 October 2018 at the Collection Nationale de Culture de Micro-organismes (CNCM), 28 rue du Dr. Roux, 75724 PARIS CEDEX 15, by virtue of the Treaty of Budapest, under number CNCM I-5372, as well as to uses of said strain. The invention also relates to a composition comprising the bacterial strain mentioned above and to a fertilization method comprising the application of this composition to a plant or to a soil.
A01N 63/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des micro-organismes, des virus, des champignons microscopiques, des animaux ou des substances produites par, ou obtenues à partir de micro-organismes, de virus, de champignons microscopiques ou d'animaux, p. ex. enzymes ou produits de fermentation
C05F 11/08 - Engrais organiques comportant l'addition de cultures bactériennes, de mycélium ou similaires
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
AGRO INDUSTRIES RECHERCHE ET DEVELOPPEMENT (France)
Inventeur(s)
Bouras Galinie, Meriem
Aymard, Caroline
Aragones, Matthieu
Abrégé
The invention relates to a process for treating lignocellulosic biomass, involving the following steps in succession: b) a step of pretreating biomass previously put in acidic conditions or at a neutral pH in a pretreatment reactor (3) in order to produce an acidic or neutral pretreated pulp (MA), alternating with b') a step of pretreating biomass previously put in acidic, neutral or basic conditions, with the optional introduction into the pretreatment reactor (3) of a sufficient amount of a basic aqueous solution (EB) to produce a basic pretreated pulp (MB), and then c) a step of enzymatic hydrolysis, in a hydrolysis reactor (16), of a mixture of the acidic or neutral pretreated pulp (MA) from step b) and the basic pretreated pulp (MB) from step b').
C12P 7/10 - Éthanol en tant que produit chimique et non en tant que boisson alcoolique préparé comme sous-produit, ou préparé à partir d'un substrat constitué par des déchets ou par des matières cellulosiques d'un substrat constitué par des matières cellulosiques
C08H 8/00 - Composés macromoléculaires dérivés de matériaux lignocellulosiques
19.
METHOD FOR CLEANING A REACTOR FOR PROCESSING A LIGNOCELLULOSIC BIOMASS
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
AGRO INDUSTRIES RECHERCHE ET DEVELOPPEMENT (France)
Inventeur(s)
Bouras Galinie, Meriem
Aymard, Caroline
Carnnot, Olivier
Abrégé
The present invention relates to a processing method at acidic or neutral pH in a reactor (4) for processing lignocellulosic biomass (P), said method including a continuous cleaning phase of the reactor which comprises introducing a basic aqueous solution (EB) into said reactor containing the biomass being processed.
Centre National De La Recherche Scientifique (France)
Institut National De La Recherche Agronomique (France)
Institute National Des Sciences Appliquees De Toulouse (France)
Inventeur(s)
Senez, Vincent
Vlandas, Alexis
Lamant, Sebastien
Cathala, Bernard
Moreau, Celine
Veronese, Gabrielle
Bozonnet, Sophie
Laville, Elisabeth
Cleret, Megane
Abrégé
A process for detecting the sensitivity of one or more polymers and/or of one or more mixtures of polymers to a compound, including the steps of exposing a plurality of individualized micro-deposits including the polymer(s) and/or the mixture(s) of polymers to the compound, and detecting, by interferometry, a variation in appearance of an assembly of micro-deposits exposed to the compound and/or a variation in the dimensions and/or refractive index of at least one of the micro-deposits exposed to the compound, linked to an interaction between the polymer(s) and/or the mixture(s) of polymers and the compound.
G01N 21/45 - RéfringencePropriétés liées à la phase, p. ex. longueur du chemin optique en utilisant des méthodes interférométriquesRéfringencePropriétés liées à la phase, p. ex. longueur du chemin optique en utilisant les méthodes de Schlieren
G01N 21/77 - Systèmes dans lesquels le matériau est soumis à une réaction chimique, le progrès ou le résultat de la réaction étant analysé en observant l'effet sur un réactif chimique
G01N 21/17 - Systèmes dans lesquels la lumière incidente est modifiée suivant les propriétés du matériau examiné
21.
PROCESS FOR PREPARING A SURFACE WITH BACTERIOSTATIC ACTIVITY AND SURFACE THUS PREPARED
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Carrot, Géraldine
Bellon-Fontaine, Marie-Noëlle
Bernardi, Sarah
Abrégé
The present invention concerns a process for imparting bacteriostatic or bactericidal properties to the surface of an object, which consists in (a) providing an object of which the surface bears groups comprising at least one oxygen atom; (b) applying, to the surface provided in step (a), a coating based on polymers of polydopamine or a derivative thereof carrying at least one function -Y, where Y is a halogen atom or a function -N(R11)(R12) in which R11 and R12 are identical or different and are a hydrogen atom, an optionally substituted alkyl group or an optionally substituted aryl group; and (c) contacting the coated surface obtained after step (b) with a solution containing at least one dihalogen and at least one diamine at a temperature greater than ambient temperature, whereby a polyionene polymer-based coating is grafted covalently to said coated surface obtained after step (b). The present invention also concerns the object thus obtained and uses thereof particularly for packaging and/or preserving fresh food products but also for purifying or decontaminating a solution or a surface.
SOCIETE DE DISTRIBUTION ET DE PRESTATION DE SERVICES SDP (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Ernenwein, Cédric
Bakan, Bénédicte
Marion, Didier
Keller, Cyril
Abrégé
The invention relates to a composition comprising at least one linear or branched ω-hydroxylated fatty acid or a derivative thereof, or a mixture of said linear or branched ω-hydroxylated fatty acids or derivatives thereof, and to the use of same to protect plants from pathogens.
A01N 37/36 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant trois liaisons à des hétéro-atomes, avec au plus deux liaisons à un halogène, p. ex. acides carboxyliques contenant au moins un groupe carboxylique ou un thio-analogue, ou d'un de leurs dérivés, et un atome d'oxygène ou de soufre lié par une liaison simple, liés au même squelette carboné, cet atome d'oxygène ou de soufre ne faisant pas partie d'un groupe carboxylique ou d'un thio-analogue, ou d'une de leurs dérivés, p. ex. acides hydroxycarboxyliques
A01P 1/00 - DésinfectantsComposés antimicrobiens ou leurs mélanges
C07H 15/10 - Radicaux acycliques non substitués par des structures cycliques liés à un atome d'oxygène d'un radical saccharide contenant des liaisons non saturées carbone-carbone
C07H 15/203 - Carbocycles monocycliques autres que des cycles cyclohexaneSystèmes carbocycliques bicycliques
C07H 13/04 - Composés contenant des radicaux saccharide estérifiés soit par l'acide carbonique ou ses dérivés, soit par des acides organiques, p. ex. acides phosphoniques par des acides carboxyliques comportant les radicaux carboxyle estérifiants liés à des atomes de carbone acycliques
C12P 19/04 - Polysaccharides, c.-à-d. composés contenant plus de cinq radicaux saccharide reliés entre eux par des liaisons glucosidiques
C12P 19/14 - Préparation de composés contenant des radicaux saccharide préparés par action d'une carbohydrase, p. ex. par action de l'alpha-amylase
C12P 19/18 - Préparation de composés contenant des radicaux saccharide préparés par action d'une transférase glycosylique, p. ex. alpha-, bêta- ou gamma-cyclodextrines
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Lao, Jonathan, Claude, Alexandre
Bossard, Cédric
Jallot, Edouard, Daniel, Albert
Wittrant, Yohann
Granel, Henri
Abrégé
2255 and/or optionally doped with strontium, and a biodegradable polymer P, this hybrid material being doped with an osteoinductive nutrient N. The invention is applicable, in particular, in the medical field.
A61L 27/44 - Matériaux composites, c.-à-d. en couches ou contenant un matériau dispersé dans une matrice constituée d'un matériau analogue ou différent comportant une matrice macromoléculaire
A61L 27/54 - Matériaux biologiquement actifs, p. ex. substances thérapeutiques
INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE (France)
INSTITUT NATIONAL RECHERCHE AGRONOMIQUE (France)
INSTITUT TECHNOLOGIQUE FCBA (FORÊT CELLULOSE BOIS- CONSTRUCTION AMEUBLEMENT) (France)
Inventeur(s)
Valentin, Romain
Mouloungui, Zéphirin
Vasquez, Francisco
Tapin-Lingua, Sandra
Da Silva Perez, Denilson
Capron, Isabelle
Jimenez-Saelices, Clara
Abrégé
The invention concerns a composition in the form of a Pickering emulsion comprising at least one dispersed phase dispersed in at least one continuous phase, and emulsifying particles capable of stabilising the emulsion, the composition being characterised in that the particles are particles of wood. The invention also relates to the use of particles of wood for stabilising a Pickering emulsion or multiple emulsion.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
UNIVERSITE DE TOURS (France)
Inventeur(s)
Grasteau, Sandrine
Duval, Elisabeth
Beauclercq, Stéphane
Abrégé
The invention relates to an in vitro method for evaluating digestive efficiency (DE) of poultry, in particular chickens, by measuring color of a sample of liquid fraction of blood of said poultry.
G01N 33/52 - Utilisation de composés ou de compositions pour des recherches colorimétriques, spectrophotométriques ou fluorométriques, p. ex. utilisation de bandes de papier indicateur
G01N 33/72 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir les pigments du sang, p. ex. l'hémoglobine, la bilirubine
27.
PEPTIDES DERIVED FROM AN AVIAN BETA-DEFENSIN 11, AND USES THEREOF
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
UNIVERSITE DE TOURS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Guyot, Nicolas
Rehault-Godbert, Sophie
Silvestre, Anne
Trapp, Sascha
Iochmann, Sophie
Reverdiau, Pascale
Aucagne, Vincent
Delmas, Agnès
Landon, Céline
Abrégé
The invention relates to peptides derived from an avian β-defensin 11 and to the uses thereof, particularly pharmaceutical and veterinary uses, for the antibacterial, antiparasitic and/or anti-invasive properties thereof.
C07K 14/465 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de vertébrés provenant d'oiseaux
A61K 38/17 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE DE STRASBOURG (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
INSTITUT FRANCAIS DE LA VIGNE ET DU VIN (France)
VRIJE UNIVERSTEIT BRUSSEL (Belgique)
Inventeur(s)
Muyldermans, Serge
Demangeat, Gérard
Ghannam, Ahmed
Ackerer, Léa
Hemmer, Caroline
Ritzenthaler, Christophe
Poignavent, Vianney
Abrégé
The present invention relates to GFLV virus-like particles and the uses thereof in various fields, such as the pharmaceutical, agro, or veterinary areas.
Institut National De La Recherche Agronomique (France)
Inventeur(s)
Ben Chaabane, Mohamed Fadhel
Rousset, Romain
Abrégé
Trichoderma Reesei, the culture medium resulting from enzyme production by the fungus, method in which: said culture medium is subjected, in a period of no longer than 30 h from the halting of production, to a separation on a filter press lined with a fabric having a porosity of 3-20 μm, so as to obtain a filtrate having a corrected optical density OD at 600 nm of less than 2.5; and the liquid phase obtained is subjected to tangenital micro-filtration on a ceramic membrane having a cut-off limit of 0.5 to 1.4 μm, so that the corrected OD at 600 nm does not exceed 0.1.
INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE TOULOUSE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Lachaux, Cléa
Walther, Thomas
Francois, Jean-Marie
Abrégé
The invention relates to a recombinant microorganism that exhibits (i) increased activity of conversion of D-ribulose-5-phosphate into D-arabinose-5-phosphate compared to the same non-modified microorganism; (ii) increased activity of catalysis of the cleavage of the D-arabinose-5-phosphate into D-glyceraldehyde-3- phosphate and glycolaldehyde compared to the same non-modified microorganism; (iii) increased activity of oxidation of the glycolaldehyde into glycolate compared to the same non-modified microorganism; and (iv) reduced activity of oxidation of the glyceraldehyde-3-phosphate into 1,3-bisphosphoglycerate compared to the same non-modified microorganism. The invention also relates to a method for producing glycolic acid from pentoses and/or hexoses using such a recombinant microorganism. The invention further relates to a method for producing glycolic acid involving a biomass production phase and a phase of bioconversion of the hexoses and/or pentoses into glycolic acid.
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Da Silva, Pedro
Abrégé
The present invention relates to insecticidal peptides and to uses thereof, in particular as plant protection agents. The invention also relates to transgenic organisms, in particular transgenic plants, expressing said peptides.
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
Institut National De La Recherche Agronomique (France)
IFP Energies Nouvelles (France)
Agro Industries Recherche Et Developpement (France)
Inventeur(s)
Aymard, Caroline
Rousset, Romain
Perotta, Larissa
Knospe, Emilia
Abrégé
The invention relates to a process for treating a lignocellulosic biomass, with:
a. Pretreatment of the biomass via at least one cooking or steam explosion operation, so as to obtain a pretreated substrate,
b. Liquid/solid separation on at least a portion of the pretreated substrate, comprising two successive substeps:
an upstream substep b1 of contacting the solid/liquid mixture performed with a continuous mixer (M) using a mixing fluid,
a downstream sub-step b2 of extraction/washing performed with a continuous filter, using a washing fluid, to obtain a solid phase enriched in solid and a plurality of liquid phases enriched in liquid, with at least partial recycling of a liquid phase extracted from the filter at the inlet of the mixer as a mixing fluid.
C08H 8/00 - Composés macromoléculaires dérivés de matériaux lignocellulosiques
C12P 7/10 - Éthanol en tant que produit chimique et non en tant que boisson alcoolique préparé comme sous-produit, ou préparé à partir d'un substrat constitué par des déchets ou par des matières cellulosiques d'un substrat constitué par des matières cellulosiques
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
INSTITUTO POLITECNICO NACIONAL (IPN) (Mexique)
Inventeur(s)
Bermudez Humaran, Luis
Torres Maravilla, Edgar
Langella, Philippe
Sanchez-Pardo, Maria Elena
Abrégé
The present invention relates to a new probiotic strain of Lactobacillus brevis, isolated from pulque and exhibiting anti-cancer properties, as well as to compositions which contain said strain.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
ECOLE NORMALE SUPERIEURE DE LYON (France)
Inventeur(s)
Bastianelli, Giacomo
Nicolas, Alain
Rogowsky, Peter
Abrégé
The present invention relates to novel transcriptional promoters which are functional during meiosis. As such, it provides novel tools, methods and compositions for protein expression during meiosis in an eukaryotic cell, and more particularly in a plant cell.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Institute of Plant Protection, Chinese Academy of Agricultural Sciences (Chine)
Inventeur(s)
Lereclus, Didier
Slamti, Leyla
Song, Fu Ping
Deng, Chao
Zhang, Jie
Abrégé
The present disclosure relates to the use of a cpcR regulator gene, which directs the expression of promoters of genes encoding Cry proteins, for reducing the sporulation of a strain of Bacillus thuringiensis, new recombinant strains of Bacillus thuringiensis and uses thereof as biopesticide.
A01N 63/02 - Substances produites par, ou obtenues à partir de micro-organismes ou d'animaux
C07K 14/325 - Peptides de cristal de Bacillus thuringiensis, c.-à-d. delta-endotoxines
C12N 15/75 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p. ex. Lactobacillus, Micromonospora pour Bacillus
C12N 3/00 - Procédés pour former ou isoler des spores
C12P 21/02 - Préparation de peptides ou de protéines comportant une séquence connue de plusieurs amino-acides, p. ex. glutathion
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
MUSEUM NATIONAL D'HISTOIRE NATURELLE (France)
ECOLE NATIONALE VETERINAIRE D'ALFORT (France)
Inventeur(s)
Bermudez-Humaran, Luis G.
Allain, Thibault
Florent, Isabelle
Langella, Philippe
Grellier, Philippe
Travers, Marie-Agnes
Polack, Bruno
Abrégé
The present invention relates to a composition exhibiting a bile-salt hydrolase activity for its use for the treatment or the prevention of giardiasis, said composition comprising a bile-salt hydrolase (BSH)enzyme, a bacterium able to secrete a BSH, a recombinant host cell able to secrete a BSH, or a combination thereof. The present invention also relates to the use of a composition exhibiting a BSH activity for the treatment or the prevention of giardiasis, and to a pharmaceutical composition or a food composition comprising, as an active principle, a BSH, a lactic acid bacterium able to secrete a BSH, or a recombinant host cell able to secrete a BSH.
A61K 38/50 - Hydrolases (3) agissant sur des liaisons carbone-azote autres que des liaisons peptidiques (3.5), p. ex. asparaginase
C12N 9/80 - Hydrolases (3.) agissant sur les liaisons carbone-azote autres que les liaisons peptidiques (3.5) agissant sur les liaisons amides des amides aliphatiques
A61K 38/00 - Préparations médicinales contenant des peptides
A61K 38/16 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
A61K 35/744 - Bactéries lactiques, p. ex. entérocoques, pédiocoques, lactocoques, streptocoques ou leuconostoques
A23L 33/135 - Bactéries ou leurs dérivés, p. ex. probiotiques
G01D 5/24 - Moyens mécaniques pour le transfert de la grandeur de sortie d'un organe sensibleMoyens pour convertir la grandeur de sortie d'un organe sensible en une autre variable, lorsque la forme ou la nature de l'organe sensible n'imposent pas un moyen de conversion déterminéTransducteurs non spécialement adaptés à une variable particulière utilisant des moyens électriques ou magnétiques influençant la valeur d'un courant ou d'une tension en faisant varier la capacité
H03K 17/955 - Commutateurs de proximité utilisant un détecteur capacitif
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
ECOLE NORMALE SUPÉRIEURE DE LYON (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
Inventeur(s)
Pain, Bertrand
Aurine, Noémie
Baquerre, Camille
Horvat, Branka
Abrégé
The disclosure relates to a method for reprogramming somatic cells from mammalian cells including human, bat and equine cells. The inventors have identified an original combination of reprogramming factors for use in methods for reprogramming somatic cells into stem cells from various species, such as bat, bovine, equine and human species. In particular, the disclosure relates to an in vitro method for preparing stem cells reprogrammed from mammalian somatic cells, said method comprising culturing mammalian somatic cells and expressing at least the following combination of reprogramming factors: (i) a reprogramming factor encoded by ESRRB gene, (ii) a reprogramming factor encoded by CDX-2 gene, and, (iii) a reprogramming factor encoded by c-MYC gene, under appropriate conditions for reprogramming said mammalian somatic cells into stem cells.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
SORBONNE UNIVERSITÉ (France)
ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
Inventeur(s)
Sokol, Harry
Natividad, Jane Mea
Lamas, Bruno
Duboc, Henri
Lavie-Richard, Mathias
Michel, Marie-Laure
Langella, Philippe
Abrégé
The present invention relates to the preventive or curative treatment of metabolic syndrome and the associated disorders with AhR agonist or microorganism producing AhR agonist.
A61K 35/747 - Lactobacilles, p. ex. L. acidophilus ou L. brevis
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p. ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A61K 35/744 - Bactéries lactiques, p. ex. entérocoques, pédiocoques, lactocoques, streptocoques ou leuconostoques
A61K 31/138 - Aryloxyalkylamines, p. ex. propranolol, tamoxifène, phénoxybenzamine
A61K 31/167 - Amides, p. ex. acides hydroxamiques ayant des cycles aromatiques, p. ex. colchicine, aténolol, progabide ayant l'atome d'azote d'un groupe carboxamide lié directement au cycle aromatique, p. ex. lidocaïne, paracétamol
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
IFP Energies nouvelles (France)
AGRO INDUSTRIES RECHERCHE ET DEVELOPPEMENT (France)
Inventeur(s)
Hudebine, Damien
Rousset, Romain
Carnnot, Olivier
Abrégé
The invention concerns a continuous method for treating a lignocellulosic biomass before enzymatic hydrolysis, said method comprising a transfer of crushed then pressed biomass to a step of impregnation by an acid liquor, the impregnated biomass dripping over the area containing the impregnation liquor, then the resulting wet biomass is pressed and sent to a steam explosion step. The impregnation liquor is prepared in a dedicated area from the used liquor from the dripping operation and/or that from the pressing operation, prior to the explosion step. The invention also concerns the facility for implementing the method.
AGRO INDUSTRIES RECHERCHE ET DEVELOPPEMENT (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Aymard, Caroline
Bouillon, Pierre-Antoine
Rousset, Romain
Carnnot, Olivier
Abrégé
The invention relates to a method for treating lignocellulosic biomass by means of acid liquor in order to produce second-generation (2G) sugary juices. These sugary juices can be used to produce other products via the biochemical route (for example: alcohols such as ethanol or butanol, or other molecules, for example solvents such as acetone, etc.). This method comprises the analysis of the liquid streams drawn off during the method and the adjustment of the composition of the impregnation liquor so as to keep the acid power of said streams constant.
AGRO INDUSTRIES RECHERCHE ET DEVELOPPEMENT (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Aymard, Caroline
Perotta, Larissa
Abrégé
The invention concerns a method for treating lignocellulosic biomass, said method comprising the following steps: a. Preparing an impregnation liquor (4) containing a chemical catalyst intended to impregnate the biomass b. Introducing the crushed biomass (6) through an inlet of an impregnation reactor (5), said inlet being situated in a first impregnation area (5a) of said impregnation reactor that comprises two superposed areas, said first impregnation area and a second so-called dewatering area (5b) above the impregnation area c. Introducing the liquor (4a) through a first liquor inlet situated in said first impregnation area (5a) of the reactor, d. Introducing said liquor (4b) into said reactor through a second liquor inlet in another area of the reactor (5d) situated below the biomass inlet in the first impregnation area (5b). The invention also concerns the facility for implementing the method.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
AGRO INDUSTRIES RECHERCHE ET DEVELOPPEMENT (France)
Inventeur(s)
Aymard, Caroline
Bouillon, Pierre-Antoine
Bouras Galinie, Meriem
Abrégé
The invention relates to a method for treating a lignocellulosic biomass comprising a solids content of at most 80% by weight, said method comprising the use of at least one reactor (9, 14) for treating said biomass, wherein, or the at least one of said reactors is supplied with biomass by a supply means (6, 11) creating an increase in pressure between the biomass inlet and the biomass outlet of said supply means, wherein said supply means is washed by circulation of a washing fluid between a washing inlet (7, 12) and a washing outlet (8, 13). According to the method, at least one portion of the washing fluid (8, 13) exiting from the fluid outlet of the or of at least one of the supply means (6, 11) is reintroduced into the washing inlet of the same supply means or of another of said supply means.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (France)
Inventeur(s)
Vernhettes, Samantha
Voxeur, Aline
Höfte, Hermanus
Mouille, Grégory
Fagard, Mathilde
Soulie, Marie-Christine
Abrégé
The present invention relates to novel phytopharmaceutical compounds, in particular to elicitors of natural plant defenses, to compositions comprising such compounds, and to uses thereof. The invention also relates in particular to a process for producing the novel phytopharmaceutical compounds.
A01N 43/16 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés hétérocycliques comportant des cycles avec un ou plusieurs atomes d'oxygène ou de soufre comme uniques hétéro-atomes du cycle avec un hétéro-atome des cycles à six chaînons avec l'oxygène comme hétéro-atome du cycle
A01N 65/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux contenant du matériel provenant d'algues, de lichens, de bryophytes, de champignons multicellulaires ou de plantes, ou leurs extraits
45.
METHOD FOR TREATING FLAX SEEDS WITH A VIEW TO IMPROVING THE FOOD VALUE OF SAME
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Chesneau, Guillaume
Guillevic, Mathieu
Germain, Antoine
Juin, Hervé
Lessire, Michel
Enjalbert, Francis
Burel, Christine
Ferlay, Anne
Abrégé
Linum usitatissimumLinum usitatissimum) with a view to improving the food value of same, in particular for animals, characterised by the fact that it comprises the following series of steps: a) Using flax seeds on condition that said seeds have a fat and/or Omega 3 fatty acid content higher than predefined values; and, only when the seeds are intended as food for monogastrics, a value in terms of water retention capacity or a low-value nutritional component lower than predefined values; b) Mixing, if there are at least two raw materials of different nature and/or quality, then fractionating, or fractionating then mixing, said seeds from step a); c) Implementing a thermal preparation step for preparing the seeds from step b) with steam and/or a water-based liquid; d) Pressurising the seeds or the mixture from step c) at a minimum pressure of 10 bars; and/or d bis) Heating the seeds or the mixture from step d), or c).
A23K 10/30 - Produits alimentaires pour animaux à base de matières d’origine végétale, p. ex. de racines, de graines ou de foinProduits alimentaires pour animaux à base de matières d’origine fongique, p. ex. de champignons
A23K 20/158 - Acides grasGraissesProduits contenant des huiles ou des graisses
A23K 10/14 - Prétraitement de produits alimentaires avec des enzymes
A23K 50/10 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les ruminants
A23K 50/75 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les oiseaux pour la volaille
A23K 50/30 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les porcs
46.
METHOD FOR TREATING HIGH-PROTEIN GRAINS WITH A VIEW TO IMPROVING THE USE THEREOF AS FOOD
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Chesneau, Guillaume
Guillevic, Mathieu
Germain, Antoine
Juin, Hervé
Lessire, Michel
Chapoutot, Patrick
Noziere, Pierre
Burel, Christine
Labussiere, Etienne
Abrégé
The present invention relates to a method for treating high-protein grains, said grains being chosen among one of the following grains: horse beans, peas, white lupin, blue lupin, yellow lupin; characterised in that it comprises, in particular, the following consecutive steps: a) using grains of at least one of the aforementioned plant species, with the condition that these grains have a protein and/or starch and/or fat content with a value no lower than a predetermined value, and at least one of the compounds of the following group: anti-nutritional factor (ANF), crude fibre, neutral detergent fibre (NDF), with a content lower than a predetermined content; b) placing grains of step a) under a minimum pressure of (10) bars for a duration of more than (10) seconds, until obtaining a temperature higher than 80°C.
A23J 1/14 - Préparation des compositions à base de protéines pour l'alimentationOuverture des œufs par grandes quantités et séparation du jaune du blanc à partir de légumineuses ou autres graines végétalesPréparation des compositions à base de protéines pour l'alimentationOuverture des œufs par grandes quantités et séparation du jaune du blanc à partir des tourteaux ou des graines oléagineuses
A23L 11/30 - Élimination des substances indésirables, p. ex. des substances amères
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Cerutti, Martine
Juliant, Sylvie
Bernon, Coralie
Abrégé
A method for preparing, in an insect cell, a recombinant baculovirus comprising one or more transgene(s) each encoding a protein maturation enzyme and n transgenes each encoding a polypeptide of interest, by homologous recombination between a replication-deficient baculovirus genome which comprises one or more transgene(s) each encoding a protein maturation enzyme and n transfer vectors each comprising one of the n transgenes each encoding a polypeptide of interest, n being an integer at least equal to 2.
INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Menny, Vincent
Rouilly, Antoine
Couret, Alain
Mazars, Dimitri
Neumeyer, David
Vandenbossche, Virginie
Monchoux, Jean
Abrégé
The invention concerns a method for producing a part in the form of a solid block from a natural material in particulate form containing scleroproteins. This method comprises a phase of heating the material, under compression at a pressure greater than or equal to 30 MPa, to a temperature greater than or equal to the denaturation temperature of the scleroproteins contained in the material. It then comprises a phase of cooling the material thus obtained to a temperature less than 100°C, while maintaining the compression during at least a part of the cooling phase.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
INSTITUT NATIONAL D'ETUDES SUPERIEURES AGRONOMIQUES DE MONTPELLIER (France)
Inventeur(s)
Sauvage, François-Xavier
Baudoin, Sacha
Vernet, Aude
Breysse, Amélie
Rettman, Julie
Abrégé
The present invention relates to an additive for treating beverages made from plant musts, particularly wine, beer, cider or fruit juices, and more particularly for improving the quality of such beverages, namely, for example, protein stability and for avoiding the cloudiness of such beverages. In its broadest application, such an additive comprises a cysteine protease and a cofactor.
A23L 2/02 - Boissons non alcooliséesCompositions sèches ou concentrés pour les fabriquer Leur préparation ou leur traitement contenant des jus de fruits ou de légumes
A23L 2/84 - Clarification ou affinage des boissons non alcooliséesÉlimination des matières non désirées utilisant des micro-organismes ou un matériau biologique, p. ex. enzymes
A23J 3/30 - Traitement des protéines pour l'alimentation par hydrolyse
A61K 38/48 - Hydrolases (3) agissant sur des liaisons peptidiques (3.4)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
TRIFYL (France)
Inventeur(s)
Trably, Eric
Paillet, Florian
Escudie, Renaud
Bernet, Nicolas
Couhert Barrau, Carole
Abrégé
The invention relates to a method for controlling the reaction medium in a dark fermentation reactor in which is carried out the fermentation of a fermentable substrate by microorganisms under anaerobic conditions, for the production of a product chosen from hydrogen and volatile fatty acids. This method comprises measuring the electrical conductivity of the reaction medium, and comparing the measured value with a predetermined threshold value associated with the product, indicative of inhibition of the production of this product by the ionic species present in the reaction medium. If the measured electrical conductivity value is greater than this threshold value, the reaction medium is considered to be unsatisfactory and to require corrective measures.
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
C12Q 3/00 - Procédés de commande sensible aux conditions du milieu
G01N 27/06 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un liquide
52.
Method for producing cellulases with pretreated lignocellulosic pomace
AGRO INDUSTRIES RECHERCHE ET DEVELOPPEMENT (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Ben Chaabane, Mohamed Fadhel
Cohen, Celine
Abrégé
The invention relates to a process for producing cellulolytic or hemicellulolytic enzymes
comprising
An enzyme production phase b) in which at least one inducer carbonaceous substrate is added, at a temperature of 25-27° C. and a pH of 4-5, process in which the said inducer substrate is a pretreated pomace obtained from a pretreatment process of lignocellulosic material that has not undergone enzymatic hydrolysis and that is added in fed-batch or continuous mode, and which has particular characteristics: a hydrolysis yield greater than 80% in a test and an apparent viscosity, measured in the test, of less than 1 Pa·s for a shear rate of 10 s−1.
C12P 7/10 - Éthanol en tant que produit chimique et non en tant que boisson alcoolique préparé comme sous-produit, ou préparé à partir d'un substrat constitué par des déchets ou par des matières cellulosiques d'un substrat constitué par des matières cellulosiques
C12N 9/42 - Hydrolases (3.) agissant sur les composés glycosyliques (3.2) agissant sur les liaisons bêta-glucosidiques-1, 4, p. ex. cellulase
C12P 21/00 - Préparation de peptides ou de protéines
53.
Bacterial strain as agents for preventing and/or treating respiratory disorders
Institut National De La Recherche Agronomique (France)
Inventeur(s)
Thomas, Muriel
Remot-Brizion, Aude
Langella, Philippe
Abrégé
The invention relates to a novel bacterial strain deposited with the CNCM under number 1-4969. This strain has properties that are useful in the treatment of respiratory disorders. The invention also relates to compositions and uses of said strain.
C12N 15/66 - Méthodes générales pour insérer un gène dans un vecteur pour former un vecteur recombinant, utilisant le clivage et la ligatureUtilisation de linkers non fonctionnels ou d'adaptateurs, p. ex. linkers contenant la séquence pour une endonucléase de restriction
C07K 14/44 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de protozoaires
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Seche, Edouard
Laurent, Fabrice
Gnahoui-David, Audrey
Boussemart-Prouvost, Anne-France
Ellouze, Mehdi
Boursin, Fanny
Mevelec, Marie-Noëlle
N'Guyen, Chi-Hung
Roy, Didier
Abrégé
SarcocystidaeSarcocystidae in which the function of the MIC1 protein and the function of the MIC3 protein are suppressed, for use in the prevention of infectious diseases in poultry.
C07K 14/44 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de protozoaires
A61P 33/02 - Antiprotozoaires, p. ex. pour le traitement de la leishmaniose, de la trichomonase, de la toxoplasmose
56.
PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE AS TRANSGLUCOSYLASE ACCEPTOR SUBSTRATES IN THE CHEMO-ENZYMATIC SYNTHESIS OF SHIGELLA FLEXNERI SPECIFIC OLIGOSACCHARIDES
C07H 15/00 - Composés contenant des radicaux hydrocarbonés ou hydrocarbonés substitués, liés directement aux hétéro-atomes des radicaux saccharide
C07H 15/10 - Radicaux acycliques non substitués par des structures cycliques liés à un atome d'oxygène d'un radical saccharide contenant des liaisons non saturées carbone-carbone
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE (France)
UNIVERSITE TOULOUSE III-PAUL SABATIER (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Heux, Stéphanie
De Simone, Alessandro
Portais, Jean-Charles
Abrégé
The application relates to a microorganism, which has been engineered to acquire methylotrophy. More particularly, the application describes a non-naturally occurring microorganism, which has been engineered to express or comprise a first enzyme and a second enzyme, wherein said first enzyme is a methanol dehydrogenase (Mdh) enzyme or a methanol oxidase (Mox) enzyme, and wherein said second enzyme is a dihydroxyacetone synthase (Das) enzyme or a transketolase enzyme. The application also describes means and applications, more particularly kits and methods, which comprise or use said microorganism.
C12N 9/04 - Oxydoréductases (1.), p. ex. luciférase agissant sur des groupes CHOH comme donneurs, p. ex. oxydase de glucose, déshydrogénase lactique (1.1)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
UNIVERSITE PARIS-SUD (France)
UNIVERSITE DE BORDEAUX (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
ECOLE NORMALE SUPERIEURE DE LYON (France)
Inventeur(s)
Aissa Abdi, Fatima Zohra
Bouchabke-Coussa, Oumaya
Delmas, Frédéric
Gendrot, Ghislaine
Hernould, Michel
Hilson, Pierre
Mireau, Hakim
Quadrado, Martine
Rogowsky, Peter
Abrégé
The present invention concerns an in vitro method for plant regeneration comprising at least a step of cultivating an explant in which the mitochondrial electron transport chain (METC) is impaired and obtaining somatic embryos, buds, shoots, roots, or meristems from said explant, to generate plantlets.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Affagard, Hervé
Schwintner, Carole
Juste, Catherine
Dore, Joël
Chapron, Audrey
Fonseca, Fernanda
David, Olivier
Abrégé
Method for lyophilisation of a simple of fecal microbiota. The present invention relates to a method for lyophilisation of a sample of fecal microbiota from a donor subject, comprising the following steps: A) mixing of a sample of fecal microbiota from a donor subject with a diluent selected from polyols, disaccharides to pentasaccharides, maltodextrins and mixtures thereof, and B) freezing the mixture obtained in A) at a temperature of less than −50° C., preferably of between −70° C. and −100° C., followed by the lyophilisation thereof.
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61K 47/36 - PolysaccharidesLeurs dérivés, p. ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
C12N 1/04 - Conservation des micro-organismes à l'état viable
A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif
A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
A61K 47/18 - AminesAmidesUréesComposés d’ammonium quaternaireAcides aminésOligopeptides ayant jusqu’à cinq acides aminés
C12Q 1/02 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir des micro-organismes viables
A61K 35/00 - Préparations médicinales contenant des substances ou leurs produits de réaction de constitution non déterminée
60.
METHOD FOR SELECTING BEE COLONIES HAVING THE VSH TRAIT AND COMPOSITION AND KIT FOR IMPLEMENTING SAME
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
UNIVERSITY OF OTAGO (Nouvelle‑Zélande)
Inventeur(s)
Mondet, Fanny
Le Conte, Yves
Mercer, Alison
Beslay, Dominique
Crauser, Didier
Abrégé
The invention concerns a method for determining if a colony of bees of the Apis mellifera species has the Varroa destructor sensitive hygiene trait (VSH). This method comprises applying, in the hive, at least one substance chosen from tricosan-2-one, pentacosan-2-one, tetracosyl acetate, heptacosan-2-one, hexacosyl acetate, nonacosan-2-one and a mixture of methyl palmitate, ethyl palmitate, methyl stearate, methyl oleate, ethyl stearate, ethyl oleate, ethyl linoleate and methyl linolenate, so as to expose the bee colony to this substance; determining a response level of the bee colony to this exposure; and comparing the response level determined in this way with a reference response level indicative of a bee colony carrying the VSH trait. This method advantageously constitutes a tool for helping select bee colonies.
A01N 35/02 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des composés organiques comportant un atome de carbone possédant deux liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. un radical aldéhyde contenant des groupes aldéhyde ou cétone, ou leurs thio-analogues, liés aliphatiquementLeurs dérivés, p. ex. acétals
A01N 37/02 - Acides carboxyliques saturés ou leurs thio-analoguesLeurs dérivés
A01N 37/06 - Acides carboxyliques non saturés ou leurs thio-analoguesLeurs dérivés
61.
COMPOSITIONS AND METHODS FOR DECREASING A POPULATION OF BILOPHILA WADSWORTHIA OR INHIBITING THE GROWTH THEREOF
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Sokol, Harry
Langella, Philippe
Natividad, Jane
Veiga, Patrick
Van Hylckama Vlieg, Johan
Abrégé
The present invention relates to the use of at least one Lactobacillus bacterium, or a composition comprising thereof or conditioned thereby, for decreasing a population of Bilophila wadsworthia or inhibiting the growth thereof.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
UNIVERSITE LIBRE DE BRUXELLES (Belgique)
UNIVERSITE DE LIEGE (Belgique)
Inventeur(s)
Nicaud, Jean-Marc
Trassaert, Marion
Thomas, Stéphane
Fickers, Patrick
Vandermies, Marie
Carly, Frédéric
Abrégé
The invention is related to an inducible promoter for improved and regulated gene expression, useful in synthetic biology and metabolic engineering. In particular, the present invention relates to a nucleotide sequence comprising the regulatory regions of an erythritol-and erythrulose-inducible promoter in yeast and uses thereof in an expression system thus allowing an improved and regulated gene expression and production of gene product.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
UNIVERSITE PARIS-SUD (France)
INSTITUT GUSTAVE ROUSSY (France)
Inventeur(s)
Carbonnel, Franck
Abrégé
The present invention relates to methods for ex vivo determining whether a patient with metastatic melanoma is likely to benefit from a treatment with an anti CTLA-4 molecule, preferably ipilimumab, by analysing the gut microbiota in a fecal sample from said patient.
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
64.
Nepovirus coat protein fusion polypeptides and their use
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE DE STRASBOURG (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Belval, Lorene
Demangeat, Gerard
Hemmer, Caroline
Ritzenthaler, Christophe
Abrégé
The present invention relates to novel fusion polypeptides and the uses thereof. The invention particularly relates to conjugated coat proteins derived from nepoviruses, virus-like particles made with such proteins, and the uses thereof. The particles of the invention can expose and/or encage molecules of interest and have utility in various fields such as the pharmaceutical, agro, or veterinary areas.
A61K 38/00 - Préparations médicinales contenant des peptides
C07H 17/08 - Hétérocycles d'au moins huit chaînons, p. ex. érythromycines
A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61K 31/277 - NitrilesIsonitriles ayant un cycle, p. ex. vérapamil
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE DE STRASBOURG (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
INSTITUT FRANCAIS DE LA VIGNE ET DU VIN (France)
VRIJE UNIVERSITEIT BRUSSEL (Belgique)
Inventeur(s)
Muyldermans, Serge
Demangeat, Gérard
Ahmed, Ghannam
Ackerer, Léa
Hemmer, Caroline
Ritzenthaler, Christophe
Poignavent, Vianney
Abrégé
The present invention relates to GFLV virus-like particles and the uses thereof in various fields such as the pharmaceutical, agro, or veterinary areas.
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Lagarde, Michel
Vericel, Evelyne
Picq, Madeleine
Guichardant, Michel
Bernoud-Hubac, Nathalie
Fourmaux, Baptiste
Abrégé
The present invention relates to AceFaPC (1-Acetyl-2-Fatty acyl-glyceroPhosphoCholine) for use in the prevention and treatment of diseases associated with an acetylcholine deficiency. The invention also relates to the AceFaPC molecule in which Fa represents an unsaturated acyl comprising at least 14 carbon atoms, and the pharmaceutical compositions comprising same.
A61K 31/661 - Acides du phosphore ou leurs esters n'ayant pas de liaison P-C, p. ex. fosfosal, dichlorvos, malathion
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 21/00 - Médicaments pour le traitement des troubles du système musculaire ou neuromusculaire
68.
Gene signatures of inflammatory disorders that relate to the liver
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Pichaud, Matthieu
Rimbaud, Pierre
Ehrlich, Stanislav
Abrégé
This invention is related to the area of characterization of inflammation in relation with the gut microbiota, in metabolic and autoimmune disorders. In particular, it relates to the identification of gene signatures which can be used as a marker predictive of inflammation associated diseases, such as liver-related metabolic disorders, in particular to the evolution of benign steatosis towards its most severe forms (steatohepatitis and cirrhosis) or autoimmune disorders, in particular inflammatory bowel diseases (Crohn's and Ulcerative Colitis). These gene signatures can therefore be used as a means of diagnosis, prognosis, stratification for drug studies, for monitoring patient and for assigning an appropriate treatment.
C12Q 1/689 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour la détection ou l’identification d’organismes pour les bactéries
C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
69.
GENERATION OF MONOCLONAL ANTIBODIES TARGETING RESPIRATORY SYNCYTIAL VIRUS (RSV) USING REGULATORY B CELLS FROM NEWBORNS (NBREGS)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MÉDICALE (INSERM) (France)
UNIVERSITÉ PARIS-SUD (France)
UNIVERSITÉ DE VERSAILLES SAINT-QUENTIN-EN-YVELINES (France)
Inventeur(s)
Lo-Man, Richard
Zhang, Xiaoming
Zhivaki, Dania
Rameix-Welti, Marie-Anne
Tissieres, Pierre
Eleouët, Jean-François
Riffault, Sabine
Mouquet, Hugo
Abrégé
The invention pertains to methods for preparing libraraies of antibodies or fragments thereof, and methods for preparing a monoclonal antibody or fragments thereof that bind, preferably specifically, to an antigen of interest, based on the use of nBreg cells. The invention further pertains to the antibody library susceptible to be produced by the methods of the invention. The invention further pertains to the monoclonal antibodies and fragments thereof susceptible to be produced by the methods of the invention, as well as the monoclonal antibodies derived from the antibody library, the pharmaceutical compositions comprisising thereof, and their use as a medicine. The invention more particularly pertains to monoclonal antibodies derived from nBregs can be used for prophylactic and therapeutic purposes for RSV infections.
Institut National des Sciences Appliquees (France)
Centre National de la Recherche Scientifique (CNRS) (France)
Institut National de la Recherche Agronomique (France)
Inventeur(s)
Soucaille, Philippe
Meynial-Salles, Isabelle
Foulquier, Céline
Riviere, Antoine
Abrégé
The present invention relates to a novel polypeptide having the enzymatic activity of reduction of NADP+ using electrons from reduced ferredoxin (Ferredoxin-NADP+ reductase activity), a polynucleotide having a nucleotide sequence encoding such polypeptide and uses thereof. The invention relates to the modulation of the Ferredoxin NADP+ reductase activity in a microorganism by varying the expression level of the polynucleotide coding for such polypeptide. The invention also relates to the production of commodity chemicals, especially ethanol, n-butanol, 1,3-propanediol, 1,2-propanediol, isopropanol and acetone by fermenting microorganisms wherein their Ferredoxin NADP+ reductase activity is modulated.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
ALLICE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (France)
Inventeur(s)
Pain, Bertrand
Baquerre, Camille
Jean, Christian
Abrégé
The present invention relates to a method for in vitro preparation of stem cells from ruminant somatic cells, by the exogenous expression of genes CDX-2 and c-MYC in said somatic cells. The invention also relates to the stem cells thus obtained, as well as to the use thereof for expanding an individual genetic background, due to the amplification of the gene pool of the initial somatic cells, for screening anti-proliferation molecules and testing the action of anti-proliferation molecules, and for replicating and testing the virulence of certain pathogens. These stem cells have some of the features of pluripotent stem cells, such as self-renewal, infinite proliferation, the detection of telomerase activity, a specific cell cycle and the expression of particular markers.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Bordes, Florence
Rigouin, Coraline
Marty, Alain
Gueroult, Marc
Andre, Isabelle
Barbe, Sophie
Percheron, Benjamin
Croux, Christian
Daboussi, Fayza
Abrégé
The present invention relates to mutant yeast strains, in particular mutant Yarrowia strains, capable of producing medium chain fatty acids compared to the parent oleaginous yeast strain from which said mutant oleaginous yeast strain derives. This invention also relates to means and methods for obtaining these mutant yeast strains.
C12P 7/64 - GraissesHuilesCires de type esterAcides gras supérieurs, c.-à-d. ayant une chaîne continue d'au moins sept atomes de carbone liée à un groupe carboxyleHuiles ou graisses oxydées
C12N 1/19 - LevuresLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
73.
USE OF THE CPCR REGULATOR GENE FOR OBTAINING NEW RECOMBINANT STRAINS OF BACILLUS THURINGIENSIS WITH REDUCED SPORULATION CAPACITY
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
INSTITUTE OF PLANT PROTECTION, CHINESE ACADEMY OF AGRICULTURAL SCIENCES (Chine)
Inventeur(s)
Lereclus, Didier
Slamti, Leyla
Song, Fu Ping
Deng, Chao
Zhang, Jie
Abrégé
The present invention relates to the use of a cpcR regulator gene, which directs the expression of promoters of genes encoding Cry proteins, for reducing the sporulation of a strain of Bacillus thuringiensis, new recombinant strains of Bacillus thuringiensis and uses thereof as biopesticide.
C07K 14/32 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant de bactéries provenant de Bacillus (G)
C07K 14/325 - Peptides de cristal de Bacillus thuringiensis, c.-à-d. delta-endotoxines
C12N 3/00 - Procédés pour former ou isoler des spores
C12N 15/75 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p. ex. Lactobacillus, Micromonospora pour Bacillus
C12P 21/02 - Préparation de peptides ou de protéines comportant une séquence connue de plusieurs amino-acides, p. ex. glutathion
A01N 63/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des micro-organismes, des virus, des champignons microscopiques, des animaux ou des substances produites par, ou obtenues à partir de micro-organismes, de virus, de champignons microscopiques ou d'animaux, p. ex. enzymes ou produits de fermentation
C12N 1/21 - BactériesLeurs milieux de culture modifiés par l'introduction de matériel génétique étranger
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
45 - Services juridiques; services de sécurité; services personnels pour individus
Produits et services
Advertising for promoting public awareness of problems relating to energy transition, georesources, aquatic environments and the environmental effects of natural and anthropogenic changes via associative services; Advertising for promoting public awareness with regard to collaboration in research, academic and leadership communities for making advances in the field of problems relating to energy transition, georesources, aquatic environments and the environmental effects of natural and anthropogenic changes; Providing, in the field of employment, via an online searchable database, advertising, accounting; Accounting for third parties, Namely account verification; Promotional services; Marketing services; Business management; Business research; Business consulting; Business information; Strategic business analysis, Namely implementation and development of commercial policies; Strategic business analysis, Namely identification, analysis and resolution of commercial problems; Strategic business analysis, Namely identification and analysis of commercial priorities; employment research services; Employment consultancy; Employment information; Career planning services; Marketing studies; Compilation of information into computer databases; database management services; Promotion of association members' interests and providing of commercial advice or assistance; Providing advice and assistance in the field of business strategy, namely research, analysis and development of commercial and organisational structures, practices, strategies and models; Planning concerning business management, namely, searching for partners for amalgamations and business take-overs as well as for business establishments; Providing advice, consultancy and information relating to all the aforesaid services. Education; Providing of training; Sporting and cultural activities; Education information; Organisation of competitions [education or entertainment]; Arranging and conducting of colloquiums; Arranging and conducting conferences and congresses; Education, namely providing conferences in the field of education and training; Providing online non-downloadable educational webinars in the field of leadership and leadership studies; Providing online non-downloadable articles, newsletters and journals; Providing non-downloadable electronic publications in the form of directives for educational programmes in the field of education and training; Organisation of awards ceremonies to recognise achievement in the field of education and training; Providing recognition and incentives by means of awards to demonstrate excellence in the field of education and training, teaching in the field of continuous training; Arranging and conducting of courses, Workshops, Training sessions, Correspondence courses, provision of conferences, providing seminars, symposia, Conferences and exhibitions; Organisation of prizes; Examinations services; Organisation and conducting of examinations; Organisation of electronic examinations; Educational assessment services; Skills assessment services; Education; Organising educational events; Providing of classroom facilities, Workshops, providing seminars, symposia, provision of conferences, Examining and expositions; Educational examination; Education and providing of training; Library services; Production and rental of audio tapes, films, videos, MP3 files, JPEG files, MPEG files, compact discs and DVDs for educational purposes; Club services (entertainment or education); Publishing; Electronic publishing service; Vocational guidance [education or training advice]; Coaching in the fields of business and finance; Design of course programmes, examination systems, examinations and tests; Arranging and conducting of entertainment events; Downloadable educational media in the field of business and finance; Providing of information, advice, consultancy and information relating to all the aforesaid services. Quality control for the accreditation of higher-education academic establishments and business schools, technical evaluation in the field of design (engineering); Scientific research; Technical research; Conducting technical project studies; Scientific research in the field of problems relating to energy transition, georesources, aquatic environments and the environmental effects of natural and anthropogenic changes, providing technological information relating to ecological and environmentally responsible innovations, quality control for certification purposes; Quality testing of goods for certification purposes, testing for the certification of quality or standards, testing, analysis and evaluation of the services of others for certification purposes, testing, analysis and evaluation of the goods and services of others for certification purposes; Certification of awards in the field of education and training; Certification of standards in the field of education and training; Certification of examiners and examination boards; Accreditation of examiners and examination boards; Certification of educational programmes; Issuing of certificates, Certification of individual achievements in accordance with required standards; Certification of educational services; Testing services for the certification of quality or standards. Legal services, providing of advice, consultancy and information relating to all the aforesaid services, searching for partners.
75.
ANTIGENIC TRIPEPTIDES DERIVED FROM MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS S-TYPE STRAINS, DERIVATIVES AND USES THEREOF
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (USA)
Inventeur(s)
Bannantine, John P.
Etienne, Gilles
Bay, Sylvie
Biet, Franck
Abrégé
The present invention is directed to an isolated synthetic tripeptide of formula H-D-Phe- N-Methyl- L-Val-L-Ala-OMe (SEQ ID NO :1 ), or a derivative thereof, and to the corresponding lipotripeptides, which are specific to Mycobacterium avium subsp. paratuberculosis (Map) S-type strain, as well as derivatives and conjugates thereof. The invention also concerns the use of these antigens in different methods and tests for detecting Map infection, especially by detecting humoral response and cell mediated response of infected animals. The invention is also directed to a genetic signature of Map and a mass spectrometry and NMR spectroscopy signature of Map presence or infection.
C07K 5/087 - Tripeptides la chaîne latérale du premier amino-acide contenant des carbocycles, p. ex. Phe, Tyr
C07K 7/06 - Peptides linéaires ne contenant que des liaisons peptidiques normales ayant de 5 à 11 amino-acides
A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
A61K 47/60 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique macromoléculaire, p. ex. une molécule oligomérique, polymérique ou dendrimérique obtenu par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone, p. ex. polyurées ou polyuréthanes le composé organique macromoléculaire étant un oligomère, un polymère ou un dendrimère de polyoxyalkylène, p. ex. PEG, PPG, PEO ou polyglycérol
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
45 - Services juridiques; services de sécurité; services personnels pour individus
Produits et services
Advertising for promoting public awareness of problems relating to energy transition, georesources, aquatic environments and the environmental effects of natural and anthropogenic changes via associative services; Advertising for promoting public awareness with regard to collaboration in research, academic and leadership communities for making advances in the field of problems relating to energy transition, georesources, aquatic environments and the environmental effects of natural and anthropogenic changes; Providing, in the field of employment, via an online searchable database, advertising, accounting; Accounting for third parties, Namely account verification; Promotional services; Marketing services; Business management; Business research; Business consulting; Business information; Strategic business analysis, Namely implementation and development of commercial policies; Strategic business analysis, Namely identification, analysis and resolution of commercial problems; Strategic business analysis, Namely identification and analysis of commercial priorities; employment research services; Employment consultancy; Employment information; Career planning services; Marketing studies; Compilation of information into computer databases; database management services; Promotion of association members' interests and providing of commercial advice or assistance; Providing advice and assistance in the field of business strategy, namely research, analysis and development of commercial and organisational structures, practices, strategies and models; Planning concerning business management, namely, searching for partners for amalgamations and business take-overs as well as for business establishments; Providing advice, consultancy and information relating to all the aforesaid services. Education; Providing of training; Sporting and cultural activities; Education information; Organisation of competitions [education or entertainment]; Arranging and conducting of colloquiums; Arranging and conducting conferences and congresses; Education, namely providing conferences in the field of education and training; Providing online non-downloadable educational webinars in the field of leadership and leadership studies; Providing online non-downloadable articles, newsletters and journals; Providing non-downloadable electronic publications in the form of directives for educational programmes in the field of education and training; Organisation of awards ceremonies to recognise achievement in the field of education and training; Providing recognition and incentives by means of awards to demonstrate excellence in the field of education and training, teaching in the field of continuous training; Arranging and conducting of courses, Workshops, Training sessions, Correspondence courses, provision of conferences, providing seminars, symposia, Conferences and exhibitions; Organisation of prizes; Examinations services; Organisation and conducting of examinations; Organisation of electronic examinations; Educational assessment services; Skills assessment services; Education; Organising educational events; Providing of classroom facilities, Workshops, providing seminars, symposia, provision of conferences, Examining and expositions; Educational examination; Education and providing of training; Library services; Production and rental of audio tapes, films, videos, MP3 files, JPEG files, MPEG files, compact discs and DVDs for educational purposes; Club services (entertainment or education); Publishing; Electronic publishing service; Vocational guidance [education or training advice]; Coaching in the fields of business and finance; Design of course programmes, examination systems, examinations and tests; Arranging and conducting of entertainment events; Downloadable educational media in the field of business and finance; Providing of information, advice, consultancy and information relating to all the aforesaid services. Quality control for the accreditation of higher-education academic establishments and business schools, technical evaluation in the field of design (engineering); Scientific research; Technical research; Conducting technical project studies; Scientific research in the field of problems relating to energy transition, georesources, aquatic environments and the environmental effects of natural and anthropogenic changes, providing technological information relating to ecological and environmentally responsible innovations, quality control for certification purposes; Quality testing of goods for certification purposes, testing for the certification of quality or standards, testing, analysis and evaluation of the services of others for certification purposes, testing, analysis and evaluation of the goods and services of others for certification purposes; Certification of awards in the field of education and training; Certification of standards in the field of education and training; Certification of examiners and examination boards; Accreditation of examiners and examination boards; Certification of educational programmes; Issuing of certificates, Certification of individual achievements in accordance with required standards; Certification of educational services; Testing services for the certification of quality or standards. Legal services, providing of advice, consultancy and information relating to all the aforesaid services, searching for partners.
77.
KIT OF ATTRACTANTS FOR ATTRACTING THE COFFEE BERRY BORER
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Frerot, Brigitte
Desquilbet, Stéphane
Abrégé
The present invention relates to a kit of attractants for attracting the coffee berry borer, Hypothenemus hampei, comprising a mixture of ethanol/methanol and (-) limonene and/or 2-ethylhexanol, as well as to the uses thereof and methods employing said kit.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
Inventeur(s)
Bourquard, Thomas
Musnier, Astrid
Poupon, Anne
Crepieux, Pascale
Reiter, Eric
Bruneau, Gilles
Abrégé
The present invention relates to an in-silico method allowing the ability of an antibody to recognize the epitope of another antibody to be predicted, based on a measurement of similarity of sequence and structure of the antibodies.
G06F 19/16 - pour la structure moléculaire, p.ex. alignement de la structure, relations structurales ou fonctionnelles, repliement protéique, topologies de domaine, ciblage de médicaments utilisant des données de structure, impliquant des structures bidimensionnelles ou tridimensionnelles
G06F 19/22 - pour la comparaison de séquences impliquant des nucléotides ou des acides aminés, p.ex. recherche d'homologie, identification de motifs ou de polymorphismes de nucléotides simples [SNP] ou alignement de séquences
79.
Microorganism sampling method, microorganism sampling device and sampling kit comprising such a sampling device
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Schwintner, Carole
Affagard, Hervé
Dore, Joël
Abrégé
A sampling method using a sampling device (2) comprising a container (5) comprising a body (6) consisting of a soft pouch, and a lid (30), in which at least one among the container (5) and the lid (30) is provided with a discharging member (40) suitable for, in an open state, discharging at least one part of the gases contained in the internal space (7) of the body (6) of the container (5), wherein the sampling method comprises the steps consisting in: —collecting a biological material in the body (6) of the container (5), and assembling the lid (30) on the neck (10) of the container (5), —and placing an internal space (7) of the body (6) of the container (5) under anaerobic conditions by placing the discharging member (40) in the open state, by compressing the body (6) of the container (5) and by placing the discharging member (40) in a closed state.
A61B 10/00 - Instruments pour le prélèvement d'échantillons corporels à des fins de diagnostic Autres procédés ou instruments pour le diagnostic, p. ex. pour le diagnostic de vaccination ou la détermination du sexe ou de la période d'ovulationInstruments pour gratter la gorge
G01N 1/10 - Dispositifs pour prélever des échantillons à l'état liquide ou fluide
80.
Methods for detecting beta-lactamase-producing bacteria
CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE DIJON (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONMIQUE (France)
Inventeur(s)
Dequaire-Rochelet, Murielle
Hartmann, Alain
Neuwirth, Catherine
Chantemesse, Benoit
Abrégé
An electrochemical method is provided for in-vitro determination of the presence of bacteria producing lactamases, in a sample that may contain such bacteria.
C12Q 1/34 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase
C12Q 1/04 - Détermination de la présence ou du type de micro-organismeEmploi de milieux sélectifs pour tester des antibiotiques ou des bactéricidesCompositions à cet effet contenant un indicateur chimique
G01N 27/48 - Systèmes utilisant la polarographie, c.-à-d. la mesure des variations d'intensité sous une tension qui varie lentement
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (France)
UNIVERSITE DE PARIS 5 RENE DESCARTES (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Vaiman, Daniel
Vilotte, Jean-Luc
Abrégé
The invention relates to a method for the in vitro diagnosis or prognosis of pre-eclampsia, comprising determining an increase or decrease in the concentration of one or more markers in a biological fluid sample.
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
82.
USE OF AHR AGONIST FOR THE PREVENTIVE OR CURATIVE TREATMENT OF METABOLIC SYNDROME AND THE ASSOCIATED DISORDERS.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
SORBONNE UNIVERSITÉ (France)
ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
Inventeur(s)
Sokol, Harry
Natividad, Jane, Mea
Lamas, Bruno
Duboc, Henri
Lavie-Richard, Mathias
Michel, Marie-Laure
Langella, Philippe
Abrégé
The present invention relates to the preventive or curative treatment of metabolic syndrome and the associated disorders with AhR agonist or microorganism producing AhR agonist.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Bissaro, Bastien
Eijsink, Vincent
Vaaje-Kolstad, Gustav
Abrégé
The present invention relates to a method of enzymatically degrading a polysaccharide, such as cellulose, comprising contacting the polysaccharide with one or more lytic polysaccharide monooxygenase (LPMO), in which the enzymatic degradation is carried out in the presence of at least one reducing agent, and hydrogen peroxide or a means which generates hydrogen peroxide in which the level of hydrogen peroxide is controlled to enhance and maintain the activity of the LPMO. The invention also extends to the additional use of hydrolytic enzymes such as hydrolases (e.g. cellulases, chitinases and/or ß-glucosidases) to increase the level or extent of degradation and to fermentation of the resulting sugars to generate an organic substance such as an alcohol, preferably ethanol, which may be used as a biofuel.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Cerutti, Martine
Juliant, Sylvie
Thery, Sylvie
Abrégé
The invention relates to a method for producing a recombinant baculovirus comprising n exogenous genes in an insect cell, by means of homologous recombination of a replication-deficient baculovirus genome and n transfer vectors, each comprising one of the n exogenous genes, n being an integer at least equal to 2.
INSTITUT NATIONAL DE LA RECHCERCHE AGRONOMIQUE (France)
AGRO INDUSTRIES RECHERCHE ET DEVELOPPEMENT (France)
Inventeur(s)
Hudebine, Damien
Rousset, Romain
Carnnot, Olivier
Abrégé
The invention concerns a continuous method for treating a lignocellulosic biomass before enzymatic hydrolysis, said method comprising a transfer of crushed then pressed biomass to a step of impregnation by an acid liquor, the impregnated biomass dripping over the area containing the impregnation liquor, then the resulting wet biomass is pressed and sent to a steam explosion step. The impregnation liquor is prepared in a dedicated area from the used liquor from the dripping operation and/or that from the pressing operation, prior to the explosion step. The invention also concerns the facility for implementing the method.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
AGRO INDUSTRIE RECHERCHES ET DEVELOPPEMENTS (France)
Inventeur(s)
Ben Chaabane, Mohamed Fadhel
Rousset, Romain
Abrégé
The invention relates to a method for separating, from a culture medium, an enzymatic cocktail and the fungus Trichoderma Reesei, the culture medium resulting from enzyme production by the fungus, method in which: said culture medium is subjected, in a period of no longer than 30 h from the halting of production, to a separation on a filter press lined with a fabric having a porosity of 3-20 μm, so as to obtain a filtrate having a corrected optical density OD at 600 nm of less than 2.5; and the liquid phase obtained is subjected to tangential micro-filtration on a ceramic membrane having a cut-off limit of 0.5 to 1.4 μm, so that the corrected OD at 600 nm does not exceed 0.1.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Brunel, Jean Michel
Peiretti, Franck
Abrégé
The present invention relates to new peroxisome proliferator-activated receptor gamma (PPARϒ) agonists, and their uses as in the prevention and/or treatment of type 2 diabetes, impaired glucose tolerance, insulin resistance syndrome, hyperlipidemia, metabolic syndrome, visceral obesity, obesity, hyperlipidemia and hypertriglyceridemia. The preparation said compounds is also described.
C07D 233/64 - Composés hétérocycliques contenant des cycles diazole-1, 3 ou diazole-1, 3 hydrogéné, non condensés avec d'autres cycles comportant deux liaisons doubles entre chaînons cycliques ou entre chaînons cycliques et chaînons non cycliques avec des radicaux hydrocarbonés substitués, liés aux atomes de carbone du cycle, p. ex. histidine
C07C 233/83 - Amides d'acides carboxyliques ayant des atomes de carbone de groupes carboxamide liés à des atomes de carbone de cycles aromatiques à six chaînons ayant l'atome d'azote d'au moins un des groupes carboxamide lié à un atome de carbone d'un radical hydrocarboné substitué par des groupes carboxyle avec le radical hydrocarboné substitué lié à l'atome d'azote du groupe carboxamide par un atome de carbone acyclique d'un squelette carboné acyclique saturé
C07D 209/36 - Atomes d'oxygène en position 3, p. ex. adrénochrome
INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Mouloungui, Zéphirin
Nsa Moto, Hermine
Abrégé
The invention relates to a process for oxidation of an unsaturated fatty acid by singlet oxygen, which comprises the preparation of a reaction system containing at least the unsaturated fatty acid and molybdate ions, in a mixture of water and an alcohol suitable for compatibilizing the unsaturated fatty acid in the emulsifying system produced in situ, this reaction system being free of exogenous emulsifying agent; and the addition of hydrogen peroxide to this reaction system. This process makes it possible to carry out, in a controlled manner, the allylic oxidation or the epoxidation of the unsaturated fatty acid.
C07D 301/12 - Synthèse du cycle de l'oxirane par oxydation de composés non saturés, ou de mélanges de composés non saturés et de composés saturés par le peroxyde d'hydrogène ou par des peroxydes ou peracides inorganiques
C07B 41/14 - Formation ou introduction de groupes fonctionnels contenant de l'oxygène de groupes peroxyde ou hydroperoxyde
90.
MUTANT YEAST STRAINS WITH ENHANCED PRODUCTION OF ERYTHRITOL OR ERYTHRULOSE
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
UNIVERSITE LIBRE DE BRUXELLES (Belgique)
UNIVERSITE DE LIEGE (Belgique)
Inventeur(s)
Nicaud, Jean-Marc
Fickers, Patrick
Carly, Frederic
Abrégé
The invention relates to a method for enhancing the erythritol and/or erythrulose productivity and/or yield of an erythritol and/or erythrulose-producing yeast strain, such as Yarrowia lipolytica, comprising inhibiting in said yeast strain the expression or the activity of an endogenous L-erythrulose kinase and/or erythritol dehydrogenase. The invention also relates to a mutant yeast strain obtained by said method.
C12N 9/12 - Transférases (2.) transférant des groupes contenant du phosphore, p. ex. kinases (2.7)
C12N 9/04 - Oxydoréductases (1.), p. ex. luciférase agissant sur des groupes CHOH comme donneurs, p. ex. oxydase de glucose, déshydrogénase lactique (1.1)
91.
METHOD OF SCREENING ANTIBACTERIAL COMPOUNDS AS INHIBITOR OF MFD
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE DE STRASBOURG (France)
Inventeur(s)
Rama Rao, Nalini
Rognan, Didier
Lereclus, Didier
Abrégé
The present invention relates to methods of screening and optionally designing compounds as inhibitors of Mfd (Mutation Frequency Decline), such compounds being useful for the treatment of bacterial infections
AGRO INDUSTRIES RECHERCHE ET DEVELOPPEMENT (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Ben Chaabane, Fadhel
Cohen, Celine
Abrégé
The invention relates to a method for producing cellulolytic or hemicellulolytic enzymes comprising: a phase a) of growing a cellulolytic microorganism in a closed reactor, in the presence of at least one carbonaceous growth substrate with a concentration of 10 to 90 g/L, at a temperature of 25-30°C and a pH of 4-5.5; a phase b) of producing enzymes into which at least one inductive carbonaceous substrate is added, at a temperature of 25-27°C and a pH of 4-5, in which method said inductive substrate is a pretreated pomace resulting from a method for pretreatment of lignocellulosic material that has not undergone enzymatic hydrolysis and which is added in fed-batch or continuous mode, and which has specific features: a hydrolysis yield of more than 80% in one test and an apparent viscosity, measured in one test, of less than 1 Pa.s for a shear rate of 10 s-1.
C12N 9/42 - Hydrolases (3.) agissant sur les composés glycosyliques (3.2) agissant sur les liaisons bêta-glucosidiques-1, 4, p. ex. cellulase
C12P 7/10 - Éthanol en tant que produit chimique et non en tant que boisson alcoolique préparé comme sous-produit, ou préparé à partir d'un substrat constitué par des déchets ou par des matières cellulosiques d'un substrat constitué par des matières cellulosiques
93.
BIOFUEL CELLS AND BIOREACTOR OF BIOCATALYTIC COMPLEX COMPRISING OF STERILIZED SOIL
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
INSTITUT D'ENSEIGNEMENT SUPERIEUR ET DE RECHERCHE EN ALIMENTATION, SANTE ANIMALE, SCIENCES AGRONOMIQUES ET DE L'ENVIRONNEMENT (VET AGRO SUP) (France)
INSTITUT NATIONAL D'ETUDES SUPERIEURES AGRONOMIQUES DE MONTPELLIER (MONTPELLIER SUP AGRO) (France)
Inventeur(s)
Fontaine, Sébastien
Alvarez, Gaël
Dubreucq, Eric
Abrégé
The present invention consists in biofuel cells and bioreactors of biocatalytic complex comprising sterilized soil; such biofuel cells and bioreactors use in vitro methods of reconstituting, manipulating and coupling multistep biochemical reactions or complete biochemical processes usually encountered in living cells using extracellular components of the intracellular metabolism (substrates, enzymes, co-factors) naturally present in soil matrix after sterilisation, such components of the intracellular metabolism may alternatively be added to said sterilized soil matrix.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
SORBONNE UNIVERSITE (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
Inventeur(s)
Jacquin-Joly, Emmanuelle
De Fouchier, Arthur
Montagne, Nicolas
Abrégé
The invention relates to a novel olfactory/pheromonal receptor (SlitOR5) of Spodoptera littoralis(Lepidoptera, Noctuidae) and the identification of the natural ligand of Slit OR5 and uses thereof.
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
C07K 14/705 - RécepteursAntigènes de surface cellulaireDéterminants de surface cellulaire
C12N 15/12 - Gènes codant pour des protéines animales
95.
INHIBITORS OF FPR2, COMPOSITIONS AND USES THEREOF FOR MODULATING INFLUENZA VIRUS REPLICATION
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
UNIVERSITE CLAUDE BERNARD LYON 1 (France)
Inventeur(s)
Alessi, Marie-Christine
Tcherniuk, Sergey
Comte, Marjorie
Riteau, Béatrice
Abrégé
The present invention relates to the modulation of influenza virus replication. Inventors in particular herein provide FPR2 modulators as well as compositions, kits and uses thereof. Also herein described are methods for preventing and/or treating influenza infections and methods for producing a vaccine composition.
A61K 38/08 - Peptides ayant de 5 à 11 amino-acides
A61K 38/10 - Peptides ayant de 12 à 20 amino-acides
A61K 38/16 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
A61K 47/51 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p. ex. les supports ou les additifs inertesAgents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p. ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification
A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques
C07K 14/00 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés
A61P 31/16 - Antiviraux pour le traitement des virus ARN de la grippe ou des rhinovirus
96.
LISTERIOLYSIN S OR RELATED PEPTIDES AS ANTIBACTERIALS
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Pizarro-Cerda, Javier
Quereda-Torres, Juan-José
Cossart, Pascale
Abrégé
The present invention relates to the use of Listeriolysin S (LLS) or related Streptolysin S (SLS)-like peptides as antibacterial peptides for therapeutic and non-therapeutic purposes.
09 - Appareils et instruments scientifiques et électriques
21 - Ustensiles, récipients, matériaux pour le ménage; verre; porcelaine; faience
Produits et services
Scientific, weighing, measuring, checking [supervision] and
teaching apparatus and instruments, namely rhizotrons;
pipettes; pipette tips for laboratory use; laboratory
pipette holders; test tubes; tubes of glass or plastic
materials for scientific use; diagnostic apparatus not for
medical use. Basins [receptacles]; tubes [receptacles]; glass flasks
[containers]; glass vials [containers]; boxes of glass;
glasses [receptacles].
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Dijoux, Emmanuel
Legendre, Laurent
Sohm, Frédéric
Abrégé
Breeding system (1) for fish belonging to the Cyprinidae family, and more particularly for zebra fish of the species Danio rerio, the said system comprising a breeding tank (2) having a bottom (2a) and side walls (2b), a spawning support (3) placed in the breeding tank (2) and comprising a platform (4) forming a spawning zone positioned a distance away from the bottom (2a) of the breeding tank (2), and a water circulating system (17) configured to modify the water level in the breeding tank (2) and at least partially flood the platform (4) of the spawning support (3), in which breeding system the spawning support (3) comprises a funnel (7) comprising a truncated conical wall (8) having a lower orifice (9) extending near the bottom (2a) of the breeding tank (2) and in fluidic communication with the water circulating system (17) by means of a pipe (11), and an upper orifice (10) extending some distance away from the bottom (2a), the platform (4) being fixed near the upper orifice (10) of the funnel (7), and the breeding system further comprises a removable shut-off member (13) configured to at least partially block off the pipe (11) of the spawning support (3) so as to increase the water level in the breeding tank (2) so as to at least partially flood the platform (4), the shut-off member (13) comprising a pipe at the end of which through-holes are formed, the said pipe having a height that is greater than a distance between the lower orifice (9) and the upper orifice (10).
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
Inventeur(s)
Thomas, Muriel
Remot-Brizion, Aude
Langella, Philippe
Abrégé
The invention relates to a novel bacterial strain deposited with the CNCM under number 1-4969. This strain has properties that are useful in the treatment of respiratory disorders. The invention also relates to compositions and uses of said strain.
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (France)
UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE (France)
INSTITUT DES SCIENCES ET DES INDUSTRIES DU VIVANT ET DE L'ENVIRONNEMENT (France)
Inventeur(s)
Lereclus, Didier
Jacques, Philippe
Gohar, Michel
Chollet, Marlène
Caradec, Thibault
Gélis-Jeanvoine, Sébastien
Abrégé
The present invention relates to a genetically modified bacterial strain, in particular a strain of Bacillus thuringiensis, expressing kurstakin and not expressing Cry toxin; to a method of producing kurstakin in a liquid medium; and to the use of kurstakin as antifungal and biosurfactant.