Abrégé

This composition comprises a compound represented by formula (A) and impurities represented by formula (X1). The composition contains the compound at 99.2% or more and impurities at more than 0% but less than 0.05% with respect to the total composition.

Classes IPC  ?

• C07J 31/00 - Stéroïdes normaux contenant un ou plusieurs atomes de soufre n'appartenant pas à un hétérocycle
• A61K 31/58 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrèneLeurs dérivés, p. ex. stéroïdes contenant des hétérocycles, p. ex. danazol, stanozolol, pancuronium ou digitogénine
• A61P 5/38 - Médicaments pour le traitement des troubles du système endocrinien des hormones surrénales

Abrégé

A method for preventing or restoring age-related loss of reproductive function in a mammal by contacting reproductive cells of the mammal with a composition that contains a flavonoid glycoside, e.g., rutin, and L-arginine. Also provided are methods for preventing or restoring age-related loss of reproductive function, for preventing or restoring age-related decline of fertility, and for reducing the risk of age-related loss of reproductive function by administering the composition to a mammal. Further disclosed is use of the composition for preventing or restoring age-related decline of fertility in a mammal.

Classes IPC  ?

• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
• A61K 31/198 - Alpha-amino-acides, p. ex. alanine ou acide édétique [EDTA]
• A61P 15/00 - Médicaments pour le traitement des troubles génitaux ou sexuelsContraceptifs

Abrégé

Disclosed is a method for producing azulene and related compounds, the method comprising a step in which a mixture that contains a compound having a hydrogenated azulene skeleton or a composition containing the compound, and at least one disulfide selected from the group consisting of an aromatic disulfide having a substituent and a long-chain alkyl disulfide is heated so as to subject the compound to a dehydrogenation reaction.

Classes IPC  ?

• C07C 5/46 - Préparation d'hydrocarbures à partir d'hydrocarbures contenant le même nombre d'atomes de carbone par déshydrogénation avec un accepteur d'hydrogène avec du soufre ou un composé contenant du soufre comme accepteur
• C07C 13/52 - AzulènesAzulènes complètement ou partiellement hydrogénés

Produits et services

Industrial chemicals; flavonoids [phenolic compounds] for industrial purposes; polyphenol; phenols. Cosmetic kits; toiletry preparations; perfumery; essential oils; hair lotions; skin lotions. Pharmaceutical preparations for human use; dietary supplements for human consumption; dietetic beverages adapted for medical purposes; dietetic foods adapted for medical purposes. Aromatic preparations for food; tea; cocoa; coffee; bread; pastries and confectionery; instant confectionery mixes; instant rice; cooked rice; noodles.

Produits et services

Industrial chemicals; flavonoids for industrial purposes; polyphenol being chemical additives for use in the manufacture of food; phenols; the foregoing containing quercetin. Cosmetic kits comprised of foundation, lipstick, and sunscreen preparations; toiletry preparations; perfumery; essential oils; hair lotions; skin lotions; the foregoing containing quercetin. Pharmaceutical preparations for prevention and treatment of angiopathy, neuropathy, inflammatory disease, and endocrine disease; dietary supplements for human consumption; dietetic beverages adapted for medical purposes; dietetic foods adapted for medical purposes; the foregoing containing quercetin. Aromatic preparations for food, namely, food flavorings being non-essential oils; tea; cocoa; coffee; bread; pastries and confectionery made of sugar; instant confectionery mixes, namely, cake mixes; instant rice; cooked rice; noodles; the foregoing containing quercetin.

Abrégé

A composition containing L-arginine and a glycosyl compound of formula (I): in which R is a moiety formed of a monosaccharide, a disaccharide, or an oligosaccharide including three to five monosaccharides; and the composition contains the glycosyl compound and L-arginine in a molar ratio of 1:1.6 to 1:3.0. Also disclosed is a method for preparing such a composition, as well as a composition prepared by the method.

Classes IPC  ?

• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
• A61K 9/08 - Solutions
• A61K 31/198 - Alpha-amino-acides, p. ex. alanine ou acide édétique [EDTA]
• A61K 31/375 - Acide ascorbique, c.-à-d. vitamine CSes sels
• A61K 31/455 - Acide nicotinique, c.-à-d. niacineSes dérivés, p. ex. esters, amides
• A61K 31/51 - Thiamines, p. ex. vitamine B1
• A61K 31/519 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles

Abrégé

A water-soluble composition including an O-glycosyl flavonoid compound, L-arginine, a sugar alcohol, and ascorbic acid or an alkali salt of ascorbic acid. The O-glycosyl flavonoid compound is rutin, isoquercitrin, or hesperidin, and a molar ratio between the O-glycosyl flavonoid compound and the sugar alcohol is 1:4.0-12.0. Also provided is a method for making the above-described water-soluble composition by combining the O-glycosyl flavonoid compound, L-arginine, the sugar alcohol, and ascorbic acid or an alkali salt thereof to form a mixture, and heating it at 110 oC-140 oC to melt the mixture.

Classes IPC  ?

• A61K 47/18 - AminesAmidesUréesComposés d’ammonium quaternaireAcides aminésOligopeptides ayant jusqu’à cinq acides aminés
• A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine

Abrégé

A water-soluble composition including an O-glycosyl flavonoid compound, L-arginine, a sugar alcohol, and ascorbic acid or an alkali salt of ascorbic acid. The O-glycosyl flavonoid compound is rutin, isoquercitrin, or hesperidin, and a molar ratio between the O-glycosyl flavonoid compound and the sugar alcohol is 1:4.0-12.0. Also provided is a method for making the above-described water-soluble composition by combining the O-glycosyl flavonoid compound, L-arginine, the sugar alcohol, and ascorbic acid or an alkali salt thereof to form a mixture, and heating it at 110° C.-140° C. to melt the mixture.

Classes IPC  ?

• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
• A61K 9/28 - DragéesPilules ou comprimés avec revêtements
• A61K 47/10 - AlcoolsPhénolsLeurs sels, p. ex. glycérolPolyéthylène glycols [PEG]PoloxamèresAlkyléthers de PEG/POE
• A61K 9/06 - OnguentsExcipients pour ceux-ci
• A61K 9/08 - Solutions
• A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat

Abrégé

A water-soluble composition containing rutin, L-arginine, and an alkali salt of ascorbic acid in which the molar ratio between the rutin, L-arginine, and the alkali salt of ascorbic acid is 1: 1.6-3.0: 0.1-2.0.

Classes IPC  ?

• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
• A61K 9/06 - OnguentsExcipients pour ceux-ci
• A61K 9/08 - Solutions
• A61K 9/20 - Pilules, pastilles ou comprimés
• A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat
• A61K 47/18 - AminesAmidesUréesComposés d’ammonium quaternaireAcides aminésOligopeptides ayant jusqu’à cinq acides aminés
• A61K 47/22 - Composés hétérocycliques, p. ex. acide ascorbique, tocophérol ou pyrrolidones
• A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire

Abrégé

A water-soluble composition containing rutin, L-arginine, and an alkali salt of ascorbic acid in which the molar ratio between the rutin, L-arginine, and the alkali salt of ascorbic acid is 1:1.6-3.0:0.1-2.0.

Classes IPC  ?

• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
• A61K 31/195 - Acides carboxyliques, p. ex. acide valproïque ayant un groupe amino
• A61K 31/375 - Acide ascorbique, c.-à-d. vitamine CSes sels
• A61K 31/714 - Cobalamines, p. ex. cyanocobalamine, vitamine B12
• A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
• A61K 31/455 - Acide nicotinique, c.-à-d. niacineSes dérivés, p. ex. esters, amides
• A61K 31/675 - Composés du phosphore ayant l'azote comme hétéro-atome d'un cycle, p. ex. phosphate de pyridoxal
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 9/08 - Solutions
• A61K 9/06 - OnguentsExcipients pour ceux-ci

Abrégé

A water-soluble pharmaceutical composition containing isoquercitrin, L-arginine, and ascorbic acid or an alkali salt thereof, in which the molar ratio between the isoquercitrin, L-arginine, and the ascorbic acid or alkali salt is 1: 1.6-2.6: 0.16-1.95.

Classes IPC  ?

• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
• A61K 9/08 - Solutions
• A61K 9/10 - DispersionsÉmulsions
• A61K 9/20 - Pilules, pastilles ou comprimés
• A61K 9/58 - Revêtements organiques contenant des polymères synthétiques solides

Produits et services

Industrial chemicals; flavonoids [phenolic compounds] for industrial purposes; polyphenol; phenols. Cosmetic kits; toiletry preparations; perfumery; essential oils; hair lotions; skin lotions. Pharmaceutical preparations for human use; dietary supplements for human consumption; dietetic beverages adapted for medical purposes; dietetic foods adapted for medical purposes. Aromatic preparations for food; tea; cocoa; coffee; bread; pastries and confectionery; instant confectionery mixes; instant rice; cooked rice; noodle-based prepared meals.

Produits et services

Industrial chemicals; flavonoids [phenolic compounds] for industrial purposes; polyphenol; phenols. Cosmetic kits; toiletry preparations; perfumery; essential oils; hair lotions; skin lotions. Pharmaceutical preparations for human use; dietary supplements for human consumption; dietetic beverages adapted for medical purposes; dietetic foods adapted for medical purposes. Aromatic preparations for food; tea; cocoa; coffee; bread; pastries and confectionery; instant confectionery mixes; instant rice; cooked rice; noodle-based prepared meals.

Produits et services

Industrial chemicals; flavonoids for industrial purposes; polyphenol being chemical additives for use in the manufacture of food; phenols Cosmetic kits in the nature of make-up kits comprised of foundation, lipstick, sunscreen preparations; non-medicated toiletry preparations; perfumery; essential oils; hair lotions; skin lotions Pharmaceutical preparations for the prevention and treatment of angiopathy, neuropathy, inflammatory disease, endocrine disease; dietary supplements for human consumption; dietetic beverages adapted for medical purposes; dietetic foods adapted for medical purposes; all of the foregoing comprised in whole or significant part of flavonoids Aromatic preparations for food, namely, food flavorings being non-essential oils; tea; cocoa; coffee; bread; pastries and confectionery made of sugar; instant confectionery mixes, namely, cake mixes; instant rice; cooked rice; noodle-based prepared meals

Produits et services

Industrial chemicals; flavonoids for industrial purposes; polyphenol being chemical additives for use in the manufacture of food; phenols Cosmetic kits in the nature of make-up kits comprised of foundation, lipstick, sunscreen preparations; non-medicated toiletry preparations; perfumery; essential oils; hair lotions; skin lotions Pharmaceutical preparations for the prevention and treatment of angiopathy, neuropathy, inflammatory disease, endocrine disease; dietary supplements for human consumption; dietetic beverages adapted for medical purposes; dietetic foods adapted for medical purposes Aromatic preparations for food, namely, food flavorings being non-essential oils; tea; cocoa; coffee; bread; pastries and confectionery made of sugar; instant confectionery mixes, namely, cake mixes; instant rice; cooked rice; noodle-based prepared meals

Abrégé

A water-soluble pharmaceutical composition containing isoquercitrin, L-arginine, and ascorbic acid or an alkali salt thereof, in which the molar ratio between the isoquercitrin, L-arginine, and the ascorbic acid or alkali salt is 1:1.6-2.6:0.16-1.95.

Classes IPC  ?

• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
• A61K 9/48 - Préparations en capsules, p. ex. de gélatine, de chocolat

Abrégé

A composition containing L-arginine and a glycosyl compound of formula (I): in which R is a moiety formed of a monosaccharide, a disaccharide, or an oligosaccharide including three to five monosaccharides; and the composition contains the glycosyl compound and L-arginine in a molar ratio of 1:1.6 to 1:3.0. Also disclosed is a method for preparing such a composition, as well as a composition prepared by the method.

Classes IPC  ?

• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
• A61K 47/18 - AminesAmidesUréesComposés d’ammonium quaternaireAcides aminésOligopeptides ayant jusqu’à cinq acides aminés
• A61K 8/00 - Cosmétiques ou préparations similaires pour la toilette
• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs

Abrégé

A method of obtaining a rutin-rich extract from a plant and a rutin-rich extract of Uncaria elliptica thus obtained.

Classes IPC  ?

• C07H 17/07 - Benzo[b]pyranones-4
• A23L 1/30 - contenant des additifs (A23L 1/308 a priorité);;
• A61K 36/18 - Magnoliophyta (angiospermes)

Abrégé

A composition containing L-arginine and a glycosyl compound of formula (I): in which R is a moiety formed of a monosaccharide, a disaccharide, or an oligosaccharide including three to five monosaccharides; and the composition contains the glycosyl compound and L-arginine in a molar ratio of 1:1.6 to 1:3.0. Also disclosed is a method for preparing such a composition, as well as a composition prepared by the method.

Classes IPC  ?

• A23L 33/10 - Modification de la qualité nutritive des alimentsProduits diététiquesLeur préparation ou leur traitement en utilisant des additifs
• A61K 8/00 - Cosmétiques ou préparations similaires pour la toilette
• A61K 31/7048 - Composés ayant des radicaux saccharide et des hétérocycles ayant l'oxygène comme hétéro-atome d'un cycle, p. ex. leucoglucosane, hespéridine, érythromycine, nystatine
• A61K 47/18 - AminesAmidesUréesComposés d’ammonium quaternaireAcides aminésOligopeptides ayant jusqu’à cinq acides aminés