The present invention relates to pyropheophorbide a analogues and their pharmaceutically acceptable salts, and compositions comprising pyropheophorbide a analogues and their pharmaceutically acceptable salts. Pyropheophorbide a analogues and pharmaceutically acceptable salts thereof are suitable for use in photodynamic therapy, cytoluminescent therapy and photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment. The present invention also relates to the use of pyropheophorbide a analogues and pharmaceutically acceptable salts thereof in the manufacture of a phototherapeutic or photodiagnostic agent, and to a method of photodynamic therapy, cytoluminescent therapy or photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment.
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
C07D 487/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes dans le système condensé, non prévus par les groupes dans lesquels le système condensé contient au moins quatre hétérocycles
The present invention relates to purpurin analogues and their pharmaceutically acceptable salts, and compositions comprising purpurin analogues and their pharmaceutically acceptable salts. Purpurin analogues and pharmaceutically acceptable salts thereof are suitable for use in photodynamic therapy, cytoluminescent therapy and photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment. The present invention also relates to the use of purpurin analogues and pharmaceutically acceptable salts thereof in the manufacture of a phototherapeutic or photodiagnostic agent, and to a method of photodynamic therapy, cytoluminescent therapy or photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment.
A61K 31/40 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
C07D 487/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes dans le système condensé, non prévus par les groupes dans lesquels le système condensé contient au moins quatre hétérocycles
3.
PORPHYRIN AND PHOSPHONIUM-PORPHYRIN BASED COMPOUNDS FOR PHOTODYNAMIC THERAPY AND DIAGNOSTICS
The present invention relates to chlorin e6 analogues and their pharmaceutically acceptable salts, and compositions comprising chlorin e6 analogues and their pharmaceutically acceptable salts. Chlorin e6 analogues and pharmaceutically acceptable salts thereof are suitable for use in photodynamic therapy, cytoluminescent therapy and photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment. The present invention also relates to the use of chlorin e6 analogues and pharmaceutically acceptable salts thereof in the manufacture of a phototherapeutic or photodiagnostic agent, and to a method of photodynamic therapy, cytoluminescent therapy or photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment.
C07F 9/6561 - Composés hétérocycliques, p. ex. contenant du phosphore comme hétéro-atome du cycle contenant des systèmes de plusieurs hétérocycles déterminants condensés entre eux ou condensés avec un carbocycle ou un système carbocyclique commun, avec ou sans autres hétérocycles non condensés
A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
A61N 5/06 - Thérapie par radiations utilisant un rayonnement lumineux
C07D 487/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes dans le système condensé, non prévus par les groupes dans lesquels le système condensé contient au moins quatre hétérocycles
The present invention relates to chlorin e6 analogues and their pharmaceutically acceptable salts, and compositions comprising chlorin e6 analogues and their pharmaceutically acceptable salts. Chlorin e6 analogues and pharmaceutically acceptable salts thereof are suitable for use in photodynamic therapy, cytoluminescent therapy and photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment. The present invention also relates to the use of chlorin e6 analogues and pharmaceutically acceptable salts thereof in the manufacture of a phototherapeutic or photodiagnostic agent, and to a method of photodynamic therapy, cytoluminescent therapy or photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment.
C07H 15/26 - Radicaux acycliques ou carbocycliques substitués par des hétérocycles
C07D 487/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes dans le système condensé, non prévus par les groupes dans lesquels le système condensé contient au moins quatre hétérocycles
The present invention relates to phyllochlorin analogues and their pharmaceutically acceptable salts, and compositions comprising phyllochlorin analogues and their pharmaceutically acceptable salts. Phyllochlorin analogues and pharmaceutically acceptable salts thereof are suitable for use in photodynamic therapy, cytoluminescent therapy and photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment. The present invention also relates to the use of phyllochlorin analogues and pharmaceutically acceptable salts thereof in the manufacture of a phototherapeutic or photodiagnostic agent, and to a method of photodynamic therapy, cytoluminescent therapy or photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment.
C07D 487/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes dans le système condensé, non prévus par les groupes dans lesquels le système condensé contient au moins quatre hétérocycles
A61K 31/41 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec plusieurs hétéro-atomes cycliques, l'un au moins étant l'azote, p. ex. tétrazole
C07F 9/6561 - Composés hétérocycliques, p. ex. contenant du phosphore comme hétéro-atome du cycle contenant des systèmes de plusieurs hétérocycles déterminants condensés entre eux ou condensés avec un carbocycle ou un système carbocyclique commun, avec ou sans autres hétérocycles non condensés
A61K 41/10 - Inactivation ou décontamination d'une préparation médicinale avant son administration à un animal ou une personne
C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées
6.
CHLORIN K ANALOGUES SUITABLE FOR USE IN PHOTODYNAMIC THERAPY (PDT)
The present invention relates to chlorin k analogues and their pharmaceutically acceptable salts, and compositions comprising chlorin k analogues and their pharmaceutically acceptable salts. Chlorin k analogues and pharmaceutically acceptable salts thereof are suitable for use in photodynamic therapy, cytoluminescent therapy and photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment. The present invention also relates to the use of chlorin k analogues and pharmaceutically acceptable salts thereof in the manufacture of a phototherapeutic or photodiagnostic agent, and to a method of photodynamic therapy, cytoluminescent therapy or photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment.
C07D 491/22 - Composés hétérocycliques contenant dans le système cyclique condensé, à la fois un ou plusieurs cycles comportant des atomes d'oxygène comme uniques hétéro-atomes du cycle, et un ou plusieurs cycles comportant des atomes d'azote comme uniques hétéro-atomes du cycle, non prévus dans les groupes , , ou dans lesquels le système condensé contient au moins quatre hétérocycles
A61K 31/409 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p. ex. sulpiride, succinimide, tolmétine, buflomédil ayant quatre de ces cycles, p. ex. dérivés de la porphine, bilirubine, biliverdine
C09K 11/06 - Substances luminescentes, p. ex. électroluminescentes, chimiluminescentes contenant des substances organiques luminescentes
G01N 33/58 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des substances marquées
09 - Appareils et instruments scientifiques et électriques
16 - Papier, carton et produits en ces matières
35 - Publicité; Affaires commerciales
36 - Services financiers, assurances et affaires immobilières
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
45 - Services juridiques; services de sécurité; services personnels pour individus
Produits et services
Computer software and computer programmes for managing data and for data processing; computer software and computer programmes for use in the field of intellectual property; computer software and publications in electronic form supplied online from databases and/or facilities provided on the Internet (including websites); downloadable computer application software in the fields of intellectual property and brand creation; computer software to enable searching of data; application development tool programs for personal handheld computers; data recordings including audio, video, still and moving images and text; downloadable electronic publications. Printed matter; printed publications, leaflets, pamphlets, brochures, reports, manuals and books; information circulars; diaries; calendars; note pads, notecards; greetings cards; stationery and writing instruments; photographs; drawings; instructional publications; instructional and teaching materials. Business research services; business consultation services; business searching, enquiries and investigations; provision of information and advisory services all relating to the aforesaid services; business information and advisory services; business appraisals and evaluations in business matters; compilation and provision of company information; preparation of business and/or market reports; database management; business franchising advisory services; brand creation services; rebranding services; market research services; marketing advice and consultancy services; provision of information, consultancy and advisory services relating to all the aforesaid services. Financial appraisals and evaluations of intellectual property assets and portfolios; intellectual property valuation services; business appraisals for financial valuation in the field of intellectual property. Education and training services in the field of intellectual property; seminars, workshops, conferences, symposia and exhibitions; library services; publishing services; providing online electronic publications; translation services; provision of information, consultancy and advisory services relating to all the aforesaid services. Technical searching and research services; technical drawings; preparation of technical drawings; new product development services; design of brand names, brand design services; design of trade marks; graphic design services; website design and creation; website design consultancy; website development; website management and maintenance; website hosting services; computer programming services; provision of information; trade mark creation services; consultancy and advisory services relating to all the aforesaid services. Legal services; intellectual property agency and attorney services; professional, advisory, licensing and consultation services relating to intellectual property; professional advisory and consultancy services relating to industrial and intellectual property; establishment, filing, prosecution, protection, management, maintenance, renewal, exploitation, acquisition, licensing and enforcement of intellectual property rights; searching and research services relating to intellectual property; legal research services; intellectual property agency services; patent agency services; trade mark agency services; intellectual property auditing services; provision of expert appraisals relating to intellectual property; legal information services; legal mediation services; legal support services; legal investigation and research services; legal consultancy services; legal watching services; legal advocacy services; legal services relating to copyright licensing, management, exploitation and enforcement; legal due diligence services; computer software licensing services; legal document preparation services; trade mark monitoring [legal services]; record keeping services in relation to intellectual property; provision of information; brand management services; name creation services; consultancy and advisory services relating to all the aforesaid services.
09 - Appareils et instruments scientifiques et électriques
16 - Papier, carton et produits en ces matières
35 - Publicité; Affaires commerciales
36 - Services financiers, assurances et affaires immobilières
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
45 - Services juridiques; services de sécurité; services personnels pour individus
Produits et services
Computer software and computer programmes for managing data and for data processing; computer software and computer programmes for use in the field of intellectual property; computer software and publications in electronic form supplied online from databases and/or facilities provided on the Internet (including websites); downloadable computer application software in the fields of intellectual property and brand creation; computer software to enable searching of data; application development tool programs for personal handheld computers; data recordings including audio, video, still and moving images and text; downloadable electronic publications. Printed matter; printed publications, leaflets, pamphlets, brochures, reports, manuals and books; information circulars; diaries; calendars; note pads, notecards; greetings cards; stationery and writing instruments; photographs; drawings; instructional publications; instructional and teaching materials. Business research services; business consultation services; business searching, enquiries and investigations; provision of information and advisory services all relating to the aforesaid services; business information and advisory services; business appraisals and evaluations in business matters; compilation and provision of company information; preparation of business and/or market reports; database management; business franchising advisory services; brand creation services; rebranding services; market research services; marketing advice and consultancy services; provision of information, consultancy and advisory services relating to all the aforesaid services. Financial appraisals and evaluations of intellectual property assets and portfolios; intellectual property valuation services; business appraisals for financial valuation in the field of intellectual property. Education and training services in the field of intellectual property; seminars, workshops, conferences, symposia and exhibitions; library services; publishing services; providing online electronic publications; translation services; provision of information, consultancy and advisory services relating to all the aforesaid services. Technical searching and research services; technical drawing; preparation of technical drawings; new product development services; design of brand names, brand design services; design of trade marks; graphic design services; website design and creation; website design consultancy; website development; website management and maintenance; website hosting services; computer programming services; trademark creation services; provision of information, consultancy and advisory services relating to all the aforesaid services. Legal services; intellectual property agency and attorney services; professional, advisory, licensing and consultation services relating to intellectual property; professional advisory and consultancy services relating to industrial and intellectual property; establishment, filing, prosecution, protection, management, maintenance, renewal, exploitation, acquisition, licensing and enforcement of intellectual property rights; searching and research services relating to intellectual property; legal research services; intellectual property agency services; patent agency services; trade mark agency services; intellectual property auditing services; provision of expert appraisals relating to intellectual property; legal information services; legal mediation services; legal support services; legal investigation and research services; legal consultancy services; legal watching services; legal advocacy services; legal services relating to copyright licensing, management, exploitation and enforcement; legal due diligence services; computer software licensing services; legal document preparation services; trade mark monitoring [legal services]; record keeping services in relation to intellectual property; brand management services; name creation services; provision of information, consultancy and advisory services relating to all the aforesaid services.
The present invention relates to phyllochlorin analogues and their pharmaceutically acceptable salts, and compositions comprising phyllochlorin analogues and their pharmaceutically acceptable salts. Phyllochlorin analogues and pharmaceutically acceptable salts thereof are suitable for use in photodynamic therapy, cytoluminescent therapy and photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment. The present invention also relates to the use of phyllochlorin analogues and pharmaceutically acceptable salts thereof in the manufacture of a phototherapeutic or photodiagnostic agent, and to a method of photodynamic therapy, cytoluminescent therapy or photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment.
C07D 487/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes dans le système condensé, non prévus par les groupes dans lesquels le système condensé contient au moins quatre hétérocycles
A61K 31/41 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec plusieurs hétéro-atomes cycliques, l'un au moins étant l'azote, p. ex. tétrazole
The present invention relates to chlorin e4 analogues and their pharmaceutically acceptable salts, and compositions comprising chlorin e4 analogues and their pharmaceutically acceptable salts. Chlorin e4 analogues and pharmaceutically acceptable salts thereof are suitable for use in photodynamic therapy, cytoluminescent therapy and photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment. The present invention also relates to the use of chlorin e4 analogues and pharmaceutically acceptable salts thereof in the manufacture of a phototherapeutic or photodiagnostic agent, and to a method of photodynamic therapy, cytoluminescent therapy or photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment.
C07D 487/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes dans le système condensé, non prévus par les groupes dans lesquels le système condensé contient au moins quatre hétérocycles
A61K 31/41 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec plusieurs hétéro-atomes cycliques, l'un au moins étant l'azote, p. ex. tétrazole
The present invention relates to reduced chlorin analogues and their pharmaceutically acceptable salts, and compositions comprising reduced chlorin analogues and their pharmaceutically acceptable salts. Reduced chlorin analogues and pharmaceutically acceptable salts thereof are suitable for use in photodynamic therapy, cytoluminescent therapy and photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment. The present invention also relates to the use of reduced chlorin analogues and pharmaceutically acceptable salts thereof in the manufacture of a phototherapeutic or photodiagnostic agent, and to a method of photodynamic therapy, cytoluminescent therapy or photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment.
C07D 487/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes dans le système condensé, non prévus par les groupes dans lesquels le système condensé contient au moins quatre hétérocycles
A61K 31/41 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec plusieurs hétéro-atomes cycliques, l'un au moins étant l'azote, p. ex. tétrazole
The present invention relates to phyllochlorin analogues and their pharmaceutically acceptable salts, and compositions comprising phyllochlorin analogues and their pharmaceutically acceptable salts. Phyllochlorin analogues and pharmaceutically acceptable salts thereof are suitable for use in photodynamic therapy, cytoluminescent therapy and photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment. The present invention also relates to the use of phyllochlorin analogues and pharmaceutically acceptable salts thereof in the manufacture of a phototherapeutic or photodiagnostic agent, and to a method of photodynamic therapy, cytoluminescent therapy or photodynamic diagnosis, for example, for treating or detecting a tumour, or for antiviral treatment.
C07D 487/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes dans le système condensé, non prévus par les groupes dans lesquels le système condensé contient au moins quatre hétérocycles
A61K 31/41 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec plusieurs hétéro-atomes cycliques, l'un au moins étant l'azote, p. ex. tétrazole
09 - Appareils et instruments scientifiques et électriques
16 - Papier, carton et produits en ces matières
35 - Publicité; Affaires commerciales
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
45 - Services juridiques; services de sécurité; services personnels pour individus
Produits et services
Computer software and computer programmes for managing data and for data processing; computer software and computer programmes for use in the field of intellectual property; computer software and publications in electronic form supplied online from databases and/or facilities provided on the Internet (including websites); computer software to enable searching of data; application development tool programmes for personal handheld computers; data recordings including audio, video, still and moving images and text; downloadable electronic publications; none of the aforesaid goods relating to veterinary care or animal welfare. Printed publications in the field of intellectual property; printed reports; newsletters; brochures, guides, manuals, pamphlets and leaflets; information circulars; diaries; calendars; stationery and writing instruments; photographs; drawings; instructional and teaching materials; none of the aforesaid goods relating to veterinary care or animal welfare. Brand management services; name creation services; market research services; business information and advisory services; business research services; business enquiries and investigations; compilation and provision of company information; preparation of business and/or market reports; database management; business franchising advisory services; marketing advice and consultancy services. Education and training services in the field of intellectual property; seminars, workshops, conferences, symposia and exhibitions; library services; publishing services; providing online electronic publications; translation services; translation services; none of the aforesaid services relating to veterinary care or animal welfare. Technical searching and research services; drawing services; preparation of technical drawings; new product development services. Professional advisory and consultancy services, all relating to industrial and intellectual property; intellectual property portfolio management and auditing; legal services; legal searching and research services; management, establishment, enforcement, maintenance and exploitation of patents, industrial designs, trade marks, copyright and other intellectual property rights; intellectual property agency and attorney services; due diligence services; computer software licensing services; record keeping services in relation to intellectual property.
14.
CHLORIN DERIVATIVE USEFUL IN PHOTODYNAMIC THERAPY AND DIAGNOSIS
The present invention relates to chlorin e4 sodium and a process for its preparation. Chlorin e4 sodium is suitable for use in photodynamic therapy, cytoluminescent therapy and photodynamic diagnosis, for example for treating or detecting a tumour. The present invention also relates to a pharmaceutical composition comprising chlorin e4 sodium, to the use of chlorin e4 sodium in the manufacture of a phototherapeutic or photodiagnostic agent, and to a method of photodynamic therapy, cytoluminescent therapy or photodynamic diagnosis, for example for treating or detecting a tumour.
C07D 487/22 - Composés hétérocycliques contenant des atomes d'azote comme uniques hétéro-atomes dans le système condensé, non prévus par les groupes dans lesquels le système condensé contient au moins quatre hétérocycles
A61K 31/41 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à cinq chaînons avec plusieurs hétéro-atomes cycliques, l'un au moins étant l'azote, p. ex. tétrazole
A61P 3/00 - Médicaments pour le traitement des troubles du métabolisme
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
A61P 17/00 - Médicaments pour le traitement des troubles dermatologiques
A61P 19/00 - Médicaments pour le traitement des troubles du squelette
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Intellectual property services; legal services; intellectual property advisory, licensing and consultancy services; technical and legal searching and research services; management, establishment, enforcement, maintenance and exploitation of patents, industrial designs, trade marks, copyright and other intellectual property rights; intellectual property agency and attorney services; translation of programs services; drawing services; preparation of technical drawings; new product development services.
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Printed matter; printed publications; leaflets, pamphlets, brochures; reports; manuals and books; instructional publications; instructional and teaching materials. Business research services; business consultation services; business searching, inquiries and investigations; provision of information and advisory services all relating to the aforesaid services. Legal services; intellectual property services; professional, advisory, licensing and consultation services relating to intellectual property; establishment, filing, prosecution, protection, management, maintenance, exploitation, licensing and enforcement of intellectual property rights; searching and research services relating to intellectual property; legal research services; Intellectual property agency services; patent agency services; trade mark agency services; name and trade mark creation services; translation services; computer programming services; provision of information and advisory services relating to all the aforesaid services.
