The Government of the United States, as represented by the Secretary of the Army (USA)
Inventeur(s)
Preece, Bradley L.
Hall, John M.
Abrégé
For see-through AR displays, the current state of art uses geometric correction to lower the display location error, however this is far from an ideal solution and requires knowing range or pose of the devices. A dual-function optic for eye display & camera is disclosed, wherein a sensor camera imaging optics pipeline with a virtual projection point at an eye's retina reduces parallax errors to zero.
Government of the United States, as represented by the Secretary of the Army (USA)
Inventeur(s)
Costello, Leo Andrew
Abrégé
A parabolic mixing nozzle including a body having an internal flow channel having a well and a plurality of parabolic shaped channels extending through the well and wherein each of the plurality of parabolic shaped channels converge together and open into an exit passage to disrupt the laminar flow of material through the parabolic mixing nozzle and a method of making products using the parabolic mixing nozzle.
B01F 25/432 - Tubes de mélange, p. ex. dans lesquels la matière est déplacée dans une direction radiale ou partiellement inversée avec des moyens pour diviser l’écoulement de matière en écoulements secondaires séparés et pour repositionner et recombiner ces écoulements secondairesMélange croisé, p. ex. en amenant la couche extérieure de la matière plus près de l'axe du tube ou vice-versa
B01F 25/433 - Tubes de mélange dans lesquels la forme du tube influence le mélange, p. ex. tubes de mélange ayant une section transversale variable ou pourvus de profils s'étendant vers l'intérieur
B01F 25/46 - Buses d’homogénéisation ou d’émulsification
B01F 101/00 - Mélange caractérisé par la nature des matières mélangées ou par le domaine d'application
B29C 45/17 - Éléments constitutifs, détails ou accessoiresOpérations auxiliaires
B29K 105/24 - Présentation, forme ou état de la matière moulée réticulée ou vulcanisée
B33Y 80/00 - Produits obtenus par fabrication additive
3.
URETHANE-MODIFIED COLD MIX ASPHALT REPAIR COMPOSITION AND METHOD OF MAKING
United States of America as Represented by The Secretary of The Army (USA)
Inventeur(s)
Cox, Benjamin C.
Casillas, Sadie E.
Abrégé
In one embodiment, a cold mix asphalt composition comprises an aggregate blend including an aggregate and a filler; and a cold mix asphalt binder including a urethane-modified asphalt binder mixed with the aggregate blend to form the cold mix asphalt composition.
United States of America as Represented by The Secretary of The Army (USA)
Inventeur(s)
Bidner, Nathaniel Jackson
Wattier, Joshua Dylan
Abrégé
In one embodiment, an enclosure device for a printed circuit board (PCB) includes an enclosure wall structure enclosing an enclosure interior which has a PCB space in which to dispose the PCB. The enclosure wall structure includes therein an internal geometry of a monolithic heat exchanger core of a monolithic heat exchanger having a plurality of internal channels. The enclosure wall structure includes one or more vents. One or more fans are configured to drive air via one or more inlets from an enclosure exterior outside of the enclosure wall structure through the internal channels and out of the one or more vents. A plurality of misters are disposed at a plurality of misting locations external of the enclosure wall structure to deliver a misting fluid to the plurality of misting locations for cooling an exterior of the enclosure wall structure.
THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Widder, Mark W.
Carbaugh, Chance M.
Van Der Schalie, William H.
Lanteri, Charlotte A.
Akers, Kevin S.
Abrégé
In this disclosure, a zebrafish model is established for rapid screening of potential drug candidates for prevention and treatment of sepsis. To this end, three endpoints (mortality, tail-fin edema, and reactive oxygen species detection) screening method is established to identify drugs of potential use among approved drugs and/or novel small molecules, and 16 drugs were identified, which target serotonin receptors, receptor tyrosine kinases, dietary supplements, antihistamine drugs, serotonin uptake inhibitors, monoamine oxidase inhibitors, and other antipsychotic drugs.
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
Government of the United States as Represented by the Secretary of the Army (USA)
Inventeur(s)
Doona, Christopher
Liu, Richard
Swager, Timothy
Abrégé
The present disclosure relates to methods and compositions used therein to dye via a bifunctional diazirene compound high-performance textiles including para-aramid (polymers of co-polymers), ultra-high molecular weight polyethylene (UHMWPE), or nylon as filament yarns and/or spun yarns of fibers or fiber-blends thereof and in a manner more quickly and more environmentally friendly.
D06P 1/384 - Procédés généraux de teinture ou d'impression des textiles ou procédés généraux de teinture du cuir, des fourrures ou des substances macromoléculaires solides de toutes formes, classés selon les teintures, les pigments ou les substances auxiliaires utilisés utilisant des colorants réactifs le groupe réactif n'étant pas directement lié au groupe hétérocyclique
D02G 3/02 - Filés ou fils caractérisés par la matière ou par les matières dont ils sont composés
Government of the United States as Represented by the Secretary of the Army (USA)
Inventeur(s)
Polk, Amee
Gardner, Warren
Kauzlarich, Michael
Sickler, Todd
Dilworth, Tobias
Craft, Kathleen
Vanvolkenburg, Tessa
Lakey, Ashley
May, Joseph
Abrégé
A portable decontamination chamber including an outer container defining a first internal volume; an interior receptacle positioned within the first internal volume and defining a second internal volume that is configured to receive an item to be decontaminated; an insulating liner configured to be positioned within the first internal volume between an interior surface of the outer container and an exterior surface of the interior receptacle; a thermite compact configured to be positioned within the first internal volume and in contact with at least a portion of the exterior surface of the interior receptacle; and an initiator configured to ignite the thermite compact to induce a biological decontamination temperature within the second internal volume in order to thoroughly and rapidly decontaminate material tainted with unwanted biological matter in a readily deployable package without the generation of additional gaseous products that increase the pressure within the decontamination chamber.
A61L 2/04 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contactAccessoires à cet effet utilisant des phénomènes physiques de la chaleur
C06B 33/12 - Compositions contenant des particules de métal, alliage, bore, silicium, sélénium ou tellure avec au moins un matériau fournissant de l'oxygène, qui est soit un oxyde métallique, soit un sel, organique ou inorganique, susceptible de donner un oxyde métallique le matériau étant formé de plusieurs composés donneurs d'oxygène
F42B 3/11 - Amorces-détonateurs pour ces cartouches caractérisées par le matériau utilisé, p. ex. pour l'enveloppe de l'amorce-détonateur ou pour les fils électriques
F42B 3/113 - Amorces-détonateurs pour ces cartouches déclenchées par voie optique, p. ex. par laser, par lampe-éclair
The Government of the United States, as Represented by the Secretary of the Army (USA)
Inventeur(s)
Pandya, Jignesh D.
Shear, Deborah
Modi, Hiren
Musyaju, Sudeep
Scultetus, Anke H.
Abrégé
A method for treating traumatic brain injury include administering to a patient having traumatic brain injury and in need of treatment an effective amount of a composition comprising resveratrol triacetate or esterified resveratrol. The traumatic brain injury may be a penetrating brain injury.
A61K 31/222 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides acycliques, p. ex. pravastatine avec des composés ayant des groupes aromatiques, p. ex. dipivéfrine, ibopamine
A61K 31/22 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides acycliques, p. ex. pravastatine
A61K 31/221 - Esters, p. ex. nitroglycérine, sélénocyanates d'acides carboxyliques d'acides acycliques, p. ex. pravastatine avec des composés ayant un groupe amino, p. ex. acétylcholine, acétylcarnitine
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
The Government of the United States, as Represented by the Secretary of the Army (USA)
Inventeur(s)
Vega, Saul J.
Snider, Eric J.
Abrégé
Methods, devices, systems, and computer-readable media are described for providing adaptive and closed loop hemorrhagic shock resuscitation. A computing device may cause activation of an automated tourniquet configured to impede extremity bleeding. The computing device may additionally cause activation of an adaptive resuscitation controller by determining a desired mean arterial pressure setpoint and causing, based on the desired mean arterial pressure setpoint, the adaptive resuscitation controller to infuse fluids into the patient. The computing device may then monitor component pressure measurements of the automated tourniquet and blood pressure parameters of the patient. The computing device may then, based on the component pressure measurements, cause modification of one or more operating parameters of the automated tourniquet. The computing device may additionally and/or alternatively, based on comparing the blood pressure parameters to the desired mean arterial pressure setpoint, cause the adaptive resuscitation controller to infuse fluids into the patient.
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
A61B 5/021 - Mesure de la pression dans le cœur ou dans les vaisseaux sanguins
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux
A61M 5/142 - Perfusion sous pression, p. ex. utilisant des pompes
G16H 20/17 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p. ex. pour s’assurer de l’administration correcte aux patients administrés par perfusion ou injection
G16H 20/30 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p. ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies ou des activités physiques, p. ex. la physiothérapie, l’acupression ou les exercices
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santéTIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
10.
Phosphodiesterase 4 Inhibitor Decreases Thrombosis in Simulated ECMO Model
THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Ross, Evan
Bynum, James A.
Cap, Andre P.
Abrégé
A majority of military casualties occur during the pre-hospital period. The cause of death is largely associated with massive traumatic bleeding that leads to organ damage due to sustained hypoxia. Currently, therapeutics are lacking at the point of injury to mitigate hypoxic damage and maintain the survivability of severe hemorrhage prior to reaching medical facilities. This invention addresses that by introducing a method of co-administering prolyl hydroxylase domain inhibitor (PHDi, MK-8617), anti-fibrinolytic agent (tranexamic acid), and bradykinin receptor antagonist (icatibant) as anti-hemorrhage agents in combination with resuscitation fluid treatment with colloid solution of 25% human albumin that has an advantage of relatively small volume requirement to maintain blood volume. In addition, a kit comprising anti-hemorrhage agents that can be easily carried to the battlefield is also provided here. The therapeutic application of those agents on or near the point of injury can stabilize hypoxia inducible factor-1 alpha and enhance blood clot formation, which improves the patient's cellular adaptation to hypoxia and reduce hemorrhage, and thus can decrease organ failure and increase the patient's survivability.
The United States of America, as represented by the Secretary of the Army (USA)
Inventeur(s)
Chavez, David
Sabatini, Jesse
Guzmán, Pablo
Wingard, Leah
Johnson, Eric
Abrégé
Disclosed herein are embodiments of an energetic compound and methods of making and using the same. Energetic compound embodiments disclosed herein exhibit physical and chemical properties that facilitate their use in various applications, such as high energy propellant plasticizers, melt-castable explosives, and the like. Efficient and safe method embodiments for making the disclosed energetic compound embodiments are described herein.
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Widstrom, Matthew D.
Kofinas, Peter
Cresce, Arthur V.
Xu, Kang
Ludwig, Kyle B.
Abrégé
The present invention is directed to aqueous solid polymer electrolytes that comprise a lithium salt and an ionic liquid, and battery cells comprising the same. The present invention is also directed to methods of making the electrolytes and methods of using the electrolytes in batteries and other electrochemical technologies.
H01M 10/0565 - Matériaux polymères, p. ex. du type gel ou du type solide
H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
H01M 4/505 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de manganèse d'oxydes ou d'hydroxydes mixtes contenant du manganèse pour insérer ou intercaler des métaux légers, p. ex. LiMn2O4 ou LiMn2OxFy
H01M 4/58 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFyEmploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de structures polyanioniques, p. ex. phosphates, silicates ou borates
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
14.
Portable test system for uniform chemical concentration testing of personal protection products and method of use
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Yurechko, Steven A
Abrégé
An apparatus for testing personal protection equipment or devices comprising an enclosure body having an air-inflatable support structure that receives an air-transferable chemical and air to maintain a substantially rigid structural integrity; a nozzle connected to the air-inflatable support structure, wherein the nozzle releases air and the air-transferable chemical from the air-inflatable support structure into the interior of the enclosure body for a selected period of time as a concentration of the air-transferable chemical in the interior of the enclosure body is at a steady state of uniformity; and a panel integrated into the enclosure body that passively releases air from the enclosure body.
United States of America as Represented by The Secretary of the Army (USA)
Inventeur(s)
Sirkis, Daniel M.
Glazier, Steven D.
Ambler, James A.
Abrégé
In one embodiment, contamination detection includes attaching a front-facing side of a detector enclosure to a ripper of a ripper machine. The detector enclosure includes a rear-facing side having a rear-facing window, two lateral-facing sides, and a bottom-facing side. A detector is disposed inside the detector enclosure. The ripper is inserted into a soil to position the rear-facing window, the two lateral-facing sides, and the bottom-facing side of the detector enclosure below a soil surface of the soil. The ripper is moved horizontally through the soil leading with the front-facing side of the detector enclosure to detect subsurface contamination via the rear-facing window using the detector.
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Fancher, Charlie
Marlow, Bonnie L.
Nicolich, Kathryn
Backes, Kelly
Malvania, Neel
Cox, Kevin Christopher
Meyer, David Henry
Kunz, Paul D.
Hill, Joshua Cartwright
Holland, William Knox
Abrégé
A system for automatically locking a control laser in a Rydberg atomic sensor may comprise an atomic vapor cell, a probe laser configured to excite the atoms in the atomic vapor cell to an intermediate energy state, and a control laser configured to excite the one or more atoms in the atomic vapor cell from the intermediate energy state to a higher energy state. The light generated by the control laser may be dithered at a pre-determined frequency. The system further comprises a photodiode configured to convert light received from the vapor cell into an electrical signal, a lock-in amplifier configured to generate an error signal based on the electrical signal received from the photo diode and a received reference oscillation frequency, and a servo configured to receive the generated error signal from the lock-in amplifier and adjust a frequency of the control laser based on the received error signal.
The Research Foundation for the State University of New York (USA)
THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Waickman, Adam
Wegman, Adam
Currier, Jeffrey
Friberg, Heather
Mccracken, Michael
Gromowski, Gregory
Abrégé
The present disclosure relates to IgA antibodies and antigen binding fragments thereof and to cocktails of antibodies and antigen binding fragments that neutralize virus infection without contributing to antibody-dependent enhancement of dengue virus infection. The present disclosure also relates to immortalized B cells that produce, and to epitopes that bind to, such antibodies and antigen binding fragments.
United States of America as Represented by The Secretary of the Army (USA)
Inventeur(s)
Jo, Kyoo D.
Hong, Sungmin
Song, Yin
Cropek, Donald M.
Oh, Seung J.
Kim, Hyunjung Anna
Abrégé
In one embodiment, a 3D printing system includes: a stage on which a substrate is disposed; first and second syringe pumps; first and second syringes; a hydrodynamic flow focusing nozzle having a central channel coupled to the first syringe to receive a printing ink and two side channels on two sides of the central channel and coupled to the second syringe to receive a sheath fluid to pinch the central channel; and a pulse generator to apply an electric potential between the hydrodynamic flow focusing nozzle and the substrate to deposit the printing ink on the substrate on-demand and control ejection frequency of the printing ink. The first syringe pump is controllable to adjust a printing ink flow rate of the printing ink to deposit the printing ink onto the substrate. The second syringe pump is controllable to adjust a sheath fluid flow rate of the sheath fluid.
B82B 3/00 - Fabrication ou traitement des nanostructures par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
19.
Systems, Methods and Media for Estimating Compensatory Reserve and Predicting Hemodynamic Decompensation Using Physiological Data
Mayo Foundation for Medical Education and Research (USA)
The Government of The United States, as Represented by the Secretary of the Army (USA)
Inventeur(s)
Techentin, Robert W.
Curry, Timothy B.
Joyner, Michael J.
Holmes, Iii, David R.
Haider, Clifton R.
Felton, Christopher L.
Gilbert, Barry K.
Van Dorn, Charlotte Sue
Carey, William A.
Convertino, Victor A.
Abrégé
In accordance with some embodiments, systems, methods, and media for estimating compensatory reserve and predicting hemodynamic decompensation using physiological data are provided. In some embodiments, a system for estimating compensatory reserve is provided, the system comprising: a processor programmed to: receive a blood pressure waveform of a subject; generate a first sample of the blood pressure waveform with a first duration; provide the sample as input to a trained CNN that was trained using samples of the first duration from blood pressure waveforms recorded from subjects while decreasing the subject's central blood volume, each sample being associated with a compensatory reserve metric; receive, from the trained CNN, a first compensatory reserve metric based on the first sample; and cause information indicative of remaining compensatory reserve to be presented.
A61B 5/02 - Détection, mesure ou enregistrement en vue de l'évaluation du système cardio-vasculaire, p. ex. mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin
A61B 5/00 - Mesure servant à établir un diagnostic Identification des individus
A61B 5/021 - Mesure de la pression dans le cœur ou dans les vaisseaux sanguins
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
G06N 3/004 - Vie artificielle, c.-à-d. agencements informatiques simulant la vie
G06N 3/008 - Vie artificielle, c.-à-d. agencements informatiques simulant la vie fondés sur des entités physiques commandées par une intelligence simulée de manière à reproduire des formes de vie intelligentes, p. ex. fondés sur des robots reproduisant les animaux ou les humains dans leur apparence ou leur comportement
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Wilke, Douglas E
Abrégé
A filter adaptor is provided for a respirator that allows the respirator to accommodate filters that have a different connection interface than the filter connection on the respirator. The adaptor includes a body having a first surface and an opposite second surface and defines a through hole. Mask locking tabs on the first surface engage with a complementary bayonet attachment the respirator. A first wall on the first surface and an inlet port gasket thereon nests within a complementary inlet port on the respirator to form an air-tight seal between the first wall and the inlet port. A valve ring on the first surface of the body engages an inlet valve on the respirator. A second wall on the second surface includes filter locking tabs that engage with a complementary filter opening of a filter. A filter gasket around the second wall forms an air-tight seal between the filter opening and the adaptor.
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Hoffman, Brian
Smith, Alex
Colonnello, Michael
Binter, Eric
Abrégé
A remote weapon system (RWS) for an unmanned ground vehicle (UGV) includes a dedicated weapon, multi-axis gimbal and ammunition handling capabilities with all operations functioning remotely and wirelessly. The RWS comprises system-level and component-level safety features which preclude the weapon of the remote weapon system from being operable if removed from the remote weapon system.
The United States of America as represented by the Secretary of the Army (USA)
Inventeur(s)
Kirk, John
Landry, Richard D
Abrégé
Apparatuses are disclosed herein for holding and securing an item. In one embodiment the item holder includes at least one layer of material between two outer layers of material. The two outer layers are made of a different material than the material of the at least one layer of material. Portions of the two outer layers and the at least one layer are secured together to form an opened ended receptacle for receiving an item. A set of hook/loop fasteners are secured to the exterior of the receptacle. The item holder also includes a material loop adapted to receive the receptacle. The material loop includes an interior surface that includes a second set of hook/loop fasters adapted to contact the first set of hook/loop fasteners. Although not required, an insertion tool may be used for insertion of receptacle into the material loop.
F41C 33/02 - Étuis, c.-à-d. gaines de pistolets, p. ex. de revolvers, comportant des moyens pour les porter ou pour le porter sur soi, p. ex. à la ceinture ou sous le bras
A45F 5/02 - Systèmes de fixation des objets aux vêtements
United States of America as Represented by The Secretary of the Army (USA)
Inventeur(s)
Rycroft, Taylor E
Donohue, Griffin
Abrégé
In one embodiment, a flotation apparatus for treating a liquid medium includes a flotation body; one or more UV lamps connected to the flotation body to be submerged in the liquid medium from the flotation body; and a filter screen connected to the flotation body to be submerged in the liquid medium upstream of the one or more UV lamps. The filter screen extends downward below a surface of the liquid medium to a lowest level which is disposed at or below a lowest level of the one or more UV lamps.
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (USA)
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Gollihar, Jimmy Dale
Goike, Jule
Hsieh, Ching-Lin
Horton, Andrew P.
Gardner, Elizabeth
Boutz, Daniel
Ellington, Andrew
Marcotte, Edward
Mclellan, Jason S.
Georgiou, George
Ippolito, Gregory C.
Abrégé
Provided herein are antibodies and antibody fragments that bind to SARS-COV-2 spike protein. Methods of using these antibodies in in vitro methods are provided. Methods of using these antibodies in vivo to treat or prevent SARS-COV-2 infections are also provided.
C07K 16/10 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant de virus de virus à ARN
A61P 31/14 - Antiviraux pour le traitement des virus ARN
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
25.
Combination of Cationic Polyacrylamide and Xanthan as Flocculation Agents for Harmful Algal Blooms
United States of America as Represented by The Secretary of the Army (USA)
Inventeur(s)
Cender, Clinton J
Page, Martin A
Kennedy, Alan J
Abrégé
A water treatment system that includes cationic polyacrylamide (cPAM) and xanthan (i.e., xanthan gum) effectively treats water contaminated with microorganisms such as harmful algal blooms (HAB). The combination of cPAM and xanthan forms cohesive thread-like flocs with the microorganisms entrapped therein. The flocs are then separated from the aqueous media, thereby removing the microorganisms. The combination of cPAM and xanthan has dramatically reduced toxicity compared to cPAM alone.
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
O'Donnell, Jr., Brian J
Kiley, Jeffrey M
Dean, Amy L
Glorioso, Michael C
Richter, Michael
Lester, Donnie
Abrégé
A vehicle or shipping-container monitoring system is provided. The system is used to sample the interior environment of the container and if needed, clear a potentially hazardous material from the interior of the container prior to conventional opening. The system includes a monitoring assembly affixed to a first through-penetration in the vehicle container, an evacuation assembly affixed to a second through-penetration in the vehicle container, and an intake penetration with a cap affixed to a third through-penetration in the vehicle container. A method is also provided to assess the interior of a vehicle or shipping container for hazardous gases or vapors prior to opening the container.
The Government of the United States, as Represented by the Secretary of the Army (USA)
Inventeur(s)
Filippov, Andrey
Nikolich, Mikeljon
Abrégé
Compositions and methods of improving an immunological response in a human subject suffering from a Pseudomonas aeruginosa in a wound comprising the step of:
(i) administering one or more isolated and purified strains of Pseudomonas aeruginosa and one or more pharmaceutically acceptable carriers or adjuvants to the wounded area of the human subject, said genomic phages interacting with innate and adaptive immune system of the human subject, while providing biological protection and/or wound recovery or stimulation; and
(ii) co-administering one or more additional genomic phages selected from genomic phages selected from Myoviridae, Podoviridae and Siphoviridae interacts and one or more pharmaceutically acceptable carriers or adjuvants to the wounded area of the human subject.
Government of the United States as Represented by the Secretary of the Army (USA)
Inventeur(s)
Fasel, Benjamin P.
Colanto, David S.
Dilalla, Robert V.
Kayhart, Tony
Abrégé
A functionally graded structure for a protective device includes a plurality of lattice structures including at least a first lattice structure having a first geometry and a second lattice structure having a second geometry. The first lattice structure with the first geometry has a first compression response property and the second lattice structure with the second geometry has a second compression response property that is different from the first compression response property.
The Government of the United States, as represented by the Secretary of the Army (USA)
Inventeur(s)
Badger, Stephen
Chen, Shuguang
Abrégé
Various embodiments relate to antenna panels with different geometries. Two or more log-periodic panels, such as log-periodic antenna panels, can be arranged along about the same plane next to one another. In one example, two panels can be employed, a first panel and a second panel. These panels can have a geometry, with the first panel having a first geometry and the second panel having a second geometry that is a mirror of the first geometry.
H01Q 11/10 - Antennes à variations périodiques ou logarithmiques
H01Q 21/08 - Réseaux d'unités d'antennes, de même polarisation, excitées individuellement et espacées entre elles les unités étant espacées le long du trajet rectiligne ou adjacent à celui-ci
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Adams, Kevin G.
Abrégé
An ammunition projectile puller includes a body with one or more jaws to engage the projectile. The jaws can generally displace axially or radially relative to an axis of a through opening, and/or rotate around an axis transverse to the through axis, all within a predetermined range of motion. The jaws obtain a reliable purchase on the projectile to facilitate the extraction. The extracted projectile is cleared from the puller by the insertion of the next projectile to be extracted. The device is thus self-locating, self-locking, self-clearing, tolerant of projectile variation, operable with different projectile types and calibers, reliable, and efficient.
UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Preece, Bradley L.
Hall, John M.
Abrégé
For see-through AR displays, the current state of art uses geometric correction to lower the display location error, however this is far from an ideal solution and requires knowing range or pose of the devices. A dual-function optic for near-to-eye display & camera is disclosed, wherein a sensor camera imaging optics pipeline with a virtual projection point at an eye's retina reduces parallax errors to zero.
Government of the United States as Represented by the Secretary of the Army (USA)
Inventeur(s)
Fasel, Benjamin P.
Colanto, David S.
Dilalla, Robert V.
Kayhart, Tony
Abrégé
A functionally graded structure for a protective device includes a plurality of lattice structures including at least a first lattice structure having a first geometry and a second lattice structure having a second geometry. The first lattice structure with the first geometry has a first compression response property and the second lattice structure with the second geometry has a second compression response property that is different from the first compression response property.
Government of the United States as Represented by the Secretary of the Army (USA)
Inventeur(s)
Fasel, Benjamin P
Colanto, David S
Dilalla, Robert V
Kayhart, Tony
Abrégé
A functionally graded structure for a protective device includes a plurality of lattice structures including at least a first lattice structure having a first geometry and a second lattice structure having a second geometry. The first lattice structure with the first geometry has a first compression response property and the second lattice structure with the second geometry has a second compression response property that is different from the first compression response property.
United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Ucak-Astarlioglu, Mine G
Hanna, Hayden A
Grotke, Michael J
Mcclelland, Zackery B
Moser, Robert D
Abrégé
A composite product includes basalt fibers and a liquid polymer resin mixed with a curing agent and infused into the basalt fibers. A method of making the composite product includes mixing a liquid polymer resin with a curing agent to form a resin matrix; infusing the resin matrix into basalt fibers; and curing the basalt fibers infused with the resin matrix to form the composite product. The method may further include adding an additive including at least one of graphene or graphite to the liquid polymer resin and the curing agent, and mixing the additive with them to form the resin matrix which is infused into the basalt fibers. It may further include weighing the additive, at about 0.1% to 0.3% of a weight of the liquid polymer resin and curing agent, to be added to the liquid polymer resin and curing agent.
The Government of the United States, as Represented by the Secretary of the Army (USA)
The Secretary of State for Defence of the United Kingdom of Great Britain and Northern Ireland (Royaume‑Uni)
Inventeur(s)
Buller, Mark Jonathan
Delves, Simon K.
Abrégé
In a general form, a running complexity analysis is computed for the skin temperature and heart rate measures as they both provide different views of the control of the thermoregulatory system. Initial Tsk and HR complexities at rest may form a baseline or normalization factor used to individualize the system. In at least one embodiment, the ratio of HR complexity to Tsk complexity is an indication of the individual's thermoregulatory strain level with one implementation for the thermoregulatory strain index.
THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Kugelman, Jeffrey R.
Larson, Peter A.
Kumar, Raina
Sanchez-Lockhart, Mariano
Abrégé
Provided herein are methods for next generation sequencing a target using universal adapter technologies and identifying and reducing error by distinguishing the signals from sequencing the target based on the location on the flow cell of the signals from sequencing the sample identifying region(s) of the adapters.
C12Q 1/6806 - Préparation d’acides nucléiques pour analyse, p. ex. pour test de réaction en chaîne par polymérase [PCR]
C12Q 1/6876 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes
C40B 50/08 - Synthèse en phase liquide, c.-à-d. dans laquelle tous les blocs servant à créer la bibliothèque sont en phase liquide ou en solution au cours de la création de la bibliothèqueProcédés particuliers de clivage à partir du support liquide
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Parker, Jason
Kayhart, Tony
Kubiak, Damian
Sykes, Robert
Abrégé
A method of forming a net shape preform for a high performance ballistic helmet includes preparing one or more full prepreg plies, preparing one or more filler prepreg plies, wherein a shape and orientation of one filler prepreg ply of the one or more filler prepreg plies is different from a shape and orientation of another filler prepreg ply of the one or more filler prepreg plies, layering the one or more full prepreg plies with one or more filler prepreg plies to form a ply stack and deforming a portion of the ply stack while constraining the ply stack by applying in-plane tensional force to the ply stack to form the net-shape preform.
B29C 70/56 - Tensionnage des renforcements avant ou pendant le façonnage
B29C 70/46 - Façonnage ou imprégnation par compression pour la fabrication d'objets de longueur définie, c.-à-d. d'objets distincts utilisant des moules opposables, p. ex. pour déformer des préimprégnés [SMC] ou des "prepregs"
B29K 77/00 - Utilisation de polyamides, p. ex. polyesteramides, comme matière de moulage
B29K 105/08 - Présentation, forme ou état de la matière moulée contenant des agents de renforcement, charges ou inserts de grande longueur, p. ex. ficelles, mèches, mats, tissus ou fils
Government of the United States, as represented by the Secretary of the Army (USA)
Inventeur(s)
Burguess, Victor Wilhelm
Rickert, Ii, Frederick Carl
Abrégé
A method of installing an underbody kit to a vehicle comprising providing a rapid underbody kit deployment crate comprising a pallet, at least one inflatable bladder, and at least one cover; removing the at least one cover from the pallet; placing the underbody kit onto the pallet and the at least one inflatable bladder; securing the at least one cover back onto the pallet; transporting the rapid underbody kit deployment crate to an assembly location; removing the at least one cover from the pallet; driving the vehicle over the rapid underbody kit deployment crate; inflating the at least one inflatable bladder to vertically lift the underbody kit into installation position; installing the underbody kit to an underbody of the vehicle; deflating the at least one inflatable bladder by releasing the fluid from the at least one inflatable bladder; and driving the vehicle away from the rapid underbody kit deployment crate.
B62D 65/02 - Assemblage de sous-ensembles ou de composants avec la caisse ou entre eux, ou positionnement de sous-ensembles ou de composants par rapport à la caisse ou à d'autres sous-ensembles ou d'autres composants
B62D 21/15 - Châssis, c.-à-d. armature sur laquelle une carrosserie peut être montée comportant des moyens amortisseurs de chocs, p. ex. châssis conçus pour changer de forme ou de dimensions d'une façon définitive ou temporaire à la suite d'une collision avec un autre corps
The United States of America as represented by the Secretary of the Army (USA)
Inventeur(s)
Cho, Sang-Yen
Zhou, Weimin
Abrégé
An optoelectronic device apparatus using active, frequency-selective metasurfaces to achieve retroreflection at a pre-determined single frequency and optionally provide signal modulation on the reflected light beam. The apparatus may use several active, frequency-selective metasurfaces to replace traditional optical lens and mirrors.
G02F 1/19 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p. ex. commutation, ouverture de porte ou modulationOptique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur basés sur des éléments à réflexion ou réfraction variable non prévus dans les groupes
H04B 10/11 - Dispositions spécifiques à la transmission en espace libre, c.-à-d. dans l’air ou le vide
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Peterson, Gregory W.
Epps, Iii, Thomas H.
Abrégé
2+ (I)
4 perfluoroalkyl; m is independently in each occurrence an integer of 0 to 12 inclusive; p is an integer of 0 to 36 inclusive, to form an amide, a thioamide, or an ester; Ar is a 1,3,5-modified phenyl, and 1.4>×>0. A process of synthesis thereof and the use to chemically modify a gaseous reactant are also provided.
B01D 71/82 - Matériaux macromoléculaires non prévus spécifiquement dans un seul des groupes caractérisés par la présence de groupes déterminés, p. ex. introduits par un post-traitement chimique
United States of America as Represented by The Secretary of the Army (USA)
Inventeur(s)
Arnett, Clint M.
Page, Martin A.
Cropek, Donald M.
Boyd, Ashley N.
Lange, Justin
Abrégé
A system and method for producing a recombinant Moringa oleifera coagulant protein (MO) in Bacillus includes the expression of a recombinant nucleic acid encoding the MO protein fused or linked to a Bacillus signal peptide (SP). The nucleic acid can also be modified by codon optimization for enhanced expression of the MO protein in bacteria. The recombinant MO protein has coagulation/flocculation activity and can be used in the treatment of contaminated water, particularly drinking water. Vectors and nucleic acid constructs encoding the MO protein and SP, and host bacterial cells are also disclosed.
C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli
C12N 15/75 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p. ex. Lactobacillus, Micromonospora pour Bacillus
Government of the United States as Represented by the Secretary of the Army (USA)
Inventeur(s)
Bruno, Ferdinando F
Bernabei, Manuele
Chiappa, Ltc Andrea
Ziegler, David
Farhadi, Nicole F
Abrégé
The disclosed subject matter relates to a method of treating of asbestos or asbestos-containing material, comprising applying to the asbestos or asbestos-containing material a composition including a treatment compound comprising at least one of hexafluoro titanium di-ammonium, potassium hexafluoro zirconate. ammonium hexafluoro phosphate. ammonium hexafluoro stannate, ammonium hexafluoro germanate, ammonium tetrafluoro borate or ammonium heptafluoro tantalite; and a fluorine scavenger compound.
G01N 21/35 - CouleurPropriétés spectrales, c.-à-d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p. ex. spectrométrie d'absorption atomique en utilisant la lumière infrarouge
G01N 1/22 - Dispositifs pour prélever des échantillons à l'état gazeux
the United States of America as represented by the Secretary of the Army (USA)
Inventeur(s)
Oppenheim, Rebecca T.
Smith, Brian J.
Kennedy, Kevin D.
Abrégé
A firearm with a real-time cartridge counter display function, comprising a firearm body, a cartridge clip, a scope, and ammunition cartridge or cartridges loaded within the cartridge clip.
F41A 9/62 - Chargeurs ou magasins munis de dispositifs indiquant le nombre de cartouches restant dans le chargeur, p. ex. indication de la dernière cartouche
F41G 1/38 - Appareils de visée télescopiques spécialement adaptés aux armes à feu individuelles ou aux pièces d'artillerieLeurs supports ou leurs montures
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Peterson, Gregory W.
Epps, Iii, Thomas H.
Abrégé
4 perfluoroalkyl; m is independently in each occurrence an integer of 0 to 12 inclusive; p is an integer of 0 to 36 inclusive, to form an amide, a thioamide, or an ester; Ar is a 1,3,5-modified phenyl, and 1.4>x>0. A process of synthesis thereof and the use to chemically modify a gaseous reactant are also provided.
B01D 71/82 - Matériaux macromoléculaires non prévus spécifiquement dans un seul des groupes caractérisés par la présence de groupes déterminés, p. ex. introduits par un post-traitement chimique
46.
Biofabrication of advanced functional materials using bacterial cellulose scaffolds
The United States of America as represented by the Secretary of the Army (USA)
Inventeur(s)
Terrell, Jessica L.
Jahnke, Justin P.
Abrégé
Gluconacetobacter and culturing media in a container; combining organic additives or inorganic additives with the active cellulose-producing bacteria in the container to produce a cellulose hydrogel matrix composed of entangled bacteria-produced cellulose nanofibers; controlling a concentration of the additives in the cellulose hydrogel matrix; and exposing the cellulose hydrogel matrix in selected thermal environment to create a biofabricated functional material.
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Peterson, Gregory W
Epps, Thomas H
Landers, John M
Abrégé
A polymer-based material includes a polymeric binder and one or more porous active materials that adsorb, chemisorb, decompose, or a combination thereof, a hazardous chemical. The polymeric binder and the one or more porous active materials are combined to form a composite bead. The polymeric binder may include a polyurethane or a styrene-based block copolymer. The porous active materials may comprise metal-organic frameworks, metal oxides, metal hydroxides, and metal hydrates. The one or more porous active materials may be between 1 and 99 wt % of a total composite mass of the composite bead. Alternatively, the one or more porous active materials may be between 80 and 95 wt % of a total composite mass of the composite bead. The hazardous chemical may include a chemical warfare agent, a simulant of chemical warfare agents, and toxic industrial chemicals.
A62D 3/33 - Procédés pour rendre les substances chimiques nuisibles inoffensives ou moins nuisibles en effectuant un changement chimique dans les substances par réaction avec des agents chimiques par fixation chimique de la substance nuisible, p. ex. par chélation ou complexation
A62B 17/00 - Vêtements de protection contre la chaleur, les agents chimiques nuisibles ou pour l'emploi à haute altitude
A62B 18/08 - Parties constitutives des casques ou masques à gaz, p. ex. fenêtres, sangles, transmetteurs de voix, dispositifs de signalisation
A62D 3/35 - Procédés pour rendre les substances chimiques nuisibles inoffensives ou moins nuisibles en effectuant un changement chimique dans les substances par réaction avec des agents chimiques par hydrolyse
A62D 3/38 - Procédés pour rendre les substances chimiques nuisibles inoffensives ou moins nuisibles en effectuant un changement chimique dans les substances par réaction avec des agents chimiques par oxydationProcédés pour rendre les substances chimiques nuisibles inoffensives ou moins nuisibles en effectuant un changement chimique dans les substances par réaction avec des agents chimiques par combustion
A62D 5/00 - Composition des matériaux pour revêtements ou vêtements protecteurs contre les agents chimiques nuisibles
C08J 3/20 - Formation de mélanges de polymères avec des additifs, p. ex. coloration
A62D 101/02 - Substances pour la guerre chimique, p. ex. inhibiteurs de la cholinestérase
A62D 101/08 - Résidus de combustion toxiques, p. ex. substances toxiques contenues dans des cendres volantes provenant de l'incinération de déchets
48.
COATING COMPRISING A TRANSITION METAL DICHALCOGENIDE, AND COATED ARTICLES AND METHODS RELATING THERETO
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Voevodin, Andrey
Aouadi, Samir
Berman, Diana
Berkebile, Stephen
Cairns, Euan
Abrégé
A coated article includes a substrate, and a coating disposed on a surface of the substrate. The coating comprises a transition metal dichalcogenide (TMD). A method of forming a coating includes dispersing a transition metal dichalcogenide (TMD) and optionally tungsten carbide in a solvent to form a mixture, spraying the mixture on a surface of a substrate, evaporating the solvent, and forming a coating on the substrate comprising the TMD.
C23C 24/10 - Revêtement à partir de poudres inorganiques en utilisant la chaleur ou une pression et la chaleur avec formation d'une phase liquide intermédiaire dans la couche
Government of the United States, as Represented by the Secretary of the Army (USA)
Inventeur(s)
Burguess, Victor Wilhelm
Rickert, Ii, Frederick Carl
Abrégé
An rapid underbody kit deployment crate including a pallet, at least one inflatable bladder, and at least one cover, wherein the underbody lift kit is constructed and arranged to store, ship, and vertically lift and lower an underbody kit for installation and removal of an underbody kit to and from a vehicle.
B62D 65/02 - Assemblage de sous-ensembles ou de composants avec la caisse ou entre eux, ou positionnement de sous-ensembles ou de composants par rapport à la caisse ou à d'autres sous-ensembles ou d'autres composants
B62D 21/15 - Châssis, c.-à-d. armature sur laquelle une carrosserie peut être montée comportant des moyens amortisseurs de chocs, p. ex. châssis conçus pour changer de forme ou de dimensions d'une façon définitive ou temporaire à la suite d'une collision avec un autre corps
The Government of the United States, as Represented by the Secretary of the Army (USA)
Inventeur(s)
Janssen, Robert S.
Novack, David
Chung, Wai Kwan
Glenn, Andrew M.
Ward, Lucy A.
Abrégé
The present disclosure relates to immunogenic compositions comprising at least one Yersinia pestis (Y. pestis) antigen, an aluminum salt adjuvant, and an oligonucleotide comprising an unmethylated cytidine-phospho-guanosine (CpG) motif. The immunogenic compositions are suitable for stimulating an immune response against Y. pestis in a subject in need thereof. The present disclosure also relates to kits and methods using the immunogenic compositions, or two separate compositions which together comprise the antigen, the aluminum salt adjuvant, and the oligonucleotide.
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p. ex. par les adjuvants chimiques
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Peterson, Gregory W.
Epps, Iii, Thomas H.
Abrégé
4 perfluoroalkyl; m is independently in each occurrence an integer of 0 to 12 inclusive; p is an integer of 0 to 36 inclusive, to form an amide, a thioamide, or an ester; Ar is a 1,3,5-modified phenyl, and 1.4>x>0. A process of synthesis thereof and the use to chemically modify a gaseous reactant are also provided.
B01D 71/82 - Matériaux macromoléculaires non prévus spécifiquement dans un seul des groupes caractérisés par la présence de groupes déterminés, p. ex. introduits par un post-traitement chimique
B01J 31/16 - Catalyseurs contenant des hydrures, des complexes de coordination ou des composés organiques contenant des complexes de coordination
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Landers, John M.
Karwacki, Christopher J.
Tovar, Trenton M.
Peterson, Gregory W.
Abrégé
The present invention relates to single thread composite fibers comprising at least one binder and at least one active catalyst for the capture and degradation of chemical threats such as chemical warfare agents (CWA), biological warfare agents, and toxic industrial chemicals (TIC) and a method for producing the same. The invention fibers are applicable to the fields of protective garments, filtration materials, and decontamination materials.
B01J 35/00 - Catalyseurs caractérisés par leur forme ou leurs propriétés physiques, en général
A62D 3/30 - Procédés pour rendre les substances chimiques nuisibles inoffensives ou moins nuisibles en effectuant un changement chimique dans les substances par réaction avec des agents chimiques
B01J 21/06 - Silicium, titane, zirconium ou hafniumLeurs oxydes ou hydroxydes
Government of the United States as Represented by the Secretary of the Army (USA)
Inventeur(s)
Mccusker, Kathryn L
Drown, Robert E
Hurley, Matthew J
Lujan, Alfredo
Abrégé
A knee pad assembly includes a protective member, a hard shell member and a hinge member connecting the protective member and the hard shell member. A first end of the hard shell member is connected to the hinge member. A second end of the hard shell member opposing the first end has an upper lip member and a lower lip member, the upper lip member and the lower lip member defining a recessed member that extends from one side of second end of the hard shell member to another side of the second end of the hard shell member.
A41D 13/06 - Vêtements protecteurs de travail ou de sport, p. ex. blouses de chirurgien ou vêtements protégeant des coups ou des chocs protégeant uniquement une partie particulière du corps les genoux ou les pieds
A41D 13/05 - Vêtements protecteurs de travail ou de sport, p. ex. blouses de chirurgien ou vêtements protégeant des coups ou des chocs protégeant uniquement une partie particulière du corps
54.
PROLYL HYDROXYLASE DOMAIN INHIBITOR TREATMENT TO IMPROVE SURVIVABILITY OF HEMORRHAGIC SHOCK
THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Cap, Andrew P.
Bynum, James A.
Wu, Xiaowu
Abrégé
A majority of military casualties occur during the pre-hospital period. The cause of death is largely associated with massive traumatic bleeding that leads to organ damage due to sustained hypoxia. Currently, therapeutics are lacking at the point of injury to mitigate hypoxic damage and maintain the survivability of severe hemorrhage prior to reaching medical facilities. This invention addresses that by introducing a method of co-administering prolyl hydroxylase domain inhibitor (PHDi, MK-8617), anti-fibrinolytic agent (tranexamic acid), and bradykinin receptor antagonist (icatibant) as anti-hemorrhage agents in combination with resuscitation fluid treatment with colloid solution of 25% human albumin that has an advantage of relatively small volume requirement to maintain blood volume. In addition, a kit comprising anti-hemorrhage agents that can be easily carried to the battlefield is also provided here. The therapeutic application of those agents on or near the point of injury can stabilize hypoxia inducible factor-1 alpha and enhance blood clot formation, which improves the patient's cellular adaptation to hypoxia and reduce hemorrhage, and thus can decrease organ failure and increase the patient's survivability.
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 31/137 - Arylalkylamines, p. ex. amphétamine, épinéphrine, salbutamol, éphédrine
A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p. ex. indolizine, bêta-carboline
A61K 31/4418 - Pyridines non condenséesLeurs dérivés hydrogénés ayant un carbocycle lié directement à l'hétérocycle, p. ex. cyproheptadine
A61K 31/472 - Isoquinoléines non condensées, p. ex. papavérine
A61K 31/506 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime non condensées et contenant d'autres hétérocycles
A61K 31/513 - PyrimidinesPyrimidines hydrogénées, p. ex. triméthoprime ayant des groupes oxo liés directement à l'hétérocycle, p. ex. cytosine
A61K 31/5377 - 1,4-Oxazines, p. ex. morpholine non condensées et contenant d'autres hétérocycles, p. ex. timolol
A61K 47/26 - Hydrates de carbone, p. ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharidesLeurs dérivés, p. ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61P 7/04 - AntihémorragiquesProfacteurs de coagulationAgents hémostatiquesAgents antifibrinolytiques
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Dindl, Frank
Jones, Kenneth
Abrégé
A recoilless gun system, comprising a gun assembly and associated ammunition for use with the gun assembly employs an integral barrel and a rear inserted ammunition round. The recoilless gun system may combine a laser initiator and a polymer cased ammunition to enable a lightweight system. In such embodiments, the cartridge case is made from a polymer that resists high pressure before extruding into small gaps.
F41A 1/10 - Canons sans recul, c.-à-d. armes à feu munies d'un système de propulsion qui ne produit pas de recul utilisant un projectile antagoniste pour équilibrer le recul
56.
Dynamic graphical user interface generation and update based on intelligent network communications
The United States of America as represented by the Secretary of the Army (USA)
Inventeur(s)
Hartnett, Regina A.
Abrégé
Ways to provide information via dynamic user interfaces including Dynamic InfoGraphics (DIG) are described. DIG representations may include various elements, such as text, icons and other graphics, tags, links, etc. and may be implemented via various types of displays or operating environments. Users may include, for example, pilots, soldiers, commanders, drivers, game players, etc. Information provided via DIG may include, for instance, data received from various types of sensors, communications received from other parties or resources, calculated or otherwise determined information (e.g., predictions associated with artificial intelligence (AI) resources such as autonomous or semi-autonomous intelligent agents), and/or other appropriate information (e.g., user inputs). The received information may be applied to one or more DIG representations or templates. AI features may be used to predict future actions, paths, goals or targets, etc. The DIG representation(s) may be updated as updated sensor information is received and/or predictions are generated.
G06F 3/048 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI]
G06F 3/0484 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] pour la commande de fonctions ou d’opérations spécifiques, p. ex. sélection ou transformation d’un objet, d’une image ou d’un élément de texte affiché, détermination d’une valeur de paramètre ou sélection d’une plage de valeurs
57.
Shaped charge devices, systems, and related methods of use
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Galloway, Kevin C.
Neely, Kelsay E.
Valles, Aimee J.
Clark, Robert J.
Frederick, Jesse L.
Abrégé
Shaped charge devices, systems, and related methods of use. A housing sheet is configurable to form at least part of a shaped charge enclosure enclosing a shaped charge and biasing an explosion in a desired direction. The housing sheet can include one or more incisions in at least one surface thereof. The housing sheet can have at least one connection mechanism integrally formed therein, and the housing sheet can be configurable to form a plurality of sizes of shaped charge housing portions. The housing sheet can also provide for forming a plurality of dimensions of the shaped charge enclosure.
The Government of the United States, as represented by the Secretary of the Army (USA)
Inventeur(s)
Scenna, Richard
Gupta, Ashwani
Abrégé
A method for controlling a fuel reformation reaction in a fuel reformation reactor is provided. Furthermore, a non-transitory computer-readable storage medium is provided, which is configured to store a program for controlling a fuel reformation reaction in a fuel reformation reactor. In addition, a fuel reformation system for controlling a fuel reformation reaction is provided, which includes a fuel reformation reactor and a control unit.
C01B 3/36 - Production d'hydrogène ou de mélanges gazeux contenant de l'hydrogène par réaction de composés organiques gazeux ou liquides avec des agents gazéifiants, p. ex. de l'eau, du gaz carbonique, de l'air par réaction d'hydrocarbures avec des agents gazéifiants avec l'oxygène ou des mélanges contenant de l'oxygène comme agents gazéifiants
59.
HIGH VOLTAGE AQUEOUS ELECTROLYTE SYSTEM FOR LITHIUM METAL OR GRAPHITE ANODE
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Xu, Kang
Wang, Chunsheng
Yang, Chongyin
Abrégé
The present invention is directed to aqueous solid state electrolytes that comprise a fluoride additive to stabilize the interface between the anode and aqueous electrolyte. The present invention is also directed to methods of making the solid state electrolyte materials and methods of using the solid state electrolyte materials in batteries and other electrochemical technologies.
H01M 10/0567 - Matériaux liquides caracterisés par les additifs
H01M 4/131 - Électrodes à base d'oxydes ou d'hydroxydes mixtes, ou de mélanges d'oxydes ou d'hydroxydes, p. ex. LiCoOx
H01M 4/134 - Électrodes à base de métaux, de Si ou d'alliages
H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
H01M 4/505 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de manganèse d'oxydes ou d'hydroxydes mixtes contenant du manganèse pour insérer ou intercaler des métaux légers, p. ex. LiMn2O4 ou LiMn2OxFy
H01M 4/583 - Matériau carboné, p. ex. composés au graphite d'intercalation ou CFx
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
United States of America as Represented by The Secretary of the Army (USA)
Inventeur(s)
Wattier, Joshua D.
Bidner, Nathaniel J.
Abrégé
In one embodiment, an enclosure device for a printed circuit board (PCB) comprises: an enclosure wall structure including therein a heater exchanger, a pipe to direct a cooling liquid through the heat exchanger, and a ducting to direct a gas through the heat exchanger to be cooled by the cooling liquid; and a PCB space adjacent to a portion of the enclosure wall structure for receiving the PCB. The ducting includes a downstream duct disposed downstream of the heat exchanger and extending through the portion of the enclosure wall structure adjacent to the PCB space to direct the cooled gas to the portion of the enclosure wall structure adjacent to the PCB space.
United States of America as Represented by The Secretary of the Army (USA)
Inventeur(s)
Smith, David L
Abrégé
An apparatus for guiding fish through a body of water having a water flow includes one or more hydrofoil element oriented in the body of water to produce an asymmetric flow field that has a fast, low turbulent flow on one side of the element and a slow, high turbulent flow on the other side of the element. Positively rheotactic fish have a preference for one side versus the other and so are guided in a desired direction. Systems and method that utilize the apparatus can be used to guide fish away from infrastructure such as dams, locks, levees, flood weirs, and other diversion points.
United States of America as Represented by The Secretary of the Army (USA)
Inventeur(s)
Church, Joshua Q.
Gonzalez, Megan E.
Richards, James E.
Salter, Richard C.
Seale, Maria A.
Ruvinsky, Alicia I.
Abrégé
The invention relates to a game simulating research and development of a product. The game may comprise a central board, function cards, form cards, a player board and HR Meeple. The central board may comprise an endless outside track. The game may comprise three phases. A concept phase may involve: creating a product requirements document; recoding the product requirements document; collecting starting resources; building an initial team; and assigning initial tasking. A development phase may comprise: following turn and round rules; completing player actions; and assigning HR units to a facility. A prototyping phase wherein a final product is made.
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (USA)
THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Krebs, Shelly
Modjarrad, Kayvon
Michael, Nelson
Dussupt, Vincent
Donofrio, Gina C.
Townsley, Samantha
Abrégé
The present disclosure is directed to monoclonal antibodies, or antigen-binding fragments thereof, that bind to coronavirus spike proteins, including the spike protein of SARS-CoV-2. These antibodies demonstrate high affinity binding to epitopes on the coronavirus spike protein and/or broad cross-reactivity to the spike protein of various coronaviruses. Compositions comprising the anti-coronavirus antibodies, nucleic acids encoding for the antibodies, recombinant expression vectors, and host cells are also disclosed. The present disclosure is also directed to methods of diagnosing, preventing or treating coronavirus infections, including infections or disease caused by SARS-CoV-2.
United States of America as Represented by The Secretary of the Army (USA)
Inventeur(s)
Oh, Seung J.
Wood, Tanner J.
Abrégé
A 3D bioprinter having a visible light source to photocure biomaterial is disclosed. The 3D bioprinter prints visible light-curable biomaterial along with viable cells, and visible light photocures the biomaterial while maintaining cell viability. Visible light 3D bioprinter systems and methods of printing are further disclosed.
B33Y 30/00 - Appareils pour la fabrication additiveLeurs parties constitutives ou accessoires à cet effet
B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
C12N 11/098 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique le support étant un polymère synthétique formé en présence des enzymes ou des cellules microbiennes
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Kesavan, Jana S
Bottiger, Jerold R
Abrégé
The present invention is directed to a passive outdoor air sampler device with various screen types and materials for efficient collection of air particles. Screens are used as a collection surface for aerosolized particles. The air sampler is suitable for long-term use in different outdoor settings with no power requirements.
G01N 15/06 - Recherche de la concentration des suspensions de particules
G01N 1/22 - Dispositifs pour prélever des échantillons à l'état gazeux
B01D 46/00 - Filtres ou procédés spécialement modifiés pour la séparation de particules dispersées dans des gaz ou des vapeurs
F24F 8/10 - Traitement, p. ex. purification, de l'air fourni aux locaux de résidence ou de travail des êtres humains autrement que par chauffage, refroidissement, humidification ou séchage par séparation, p. ex. par filtrage
66.
Renewable highly biobased polybenzoxazine thermosets for composite applications
The United States of America as represented by The Secretary of the Army (USA)
Inventeur(s)
Palmese, Giuseppe R.
Yadav, Santosh K.
Lascala, John J.
Abrégé
Benzoxazine compounds, methods of making them, polymers made therefrom and methods of polymerizing the benzoxazines. These renewable benzoxazine monomers and polymers that utilize the variety of building blocks found in renewable plant biomass, demonstrate excellent processability and large temperature windows for processing of resin systems.
C07D 413/06 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
C07D 307/52 - Radicaux substitués par des atomes d'azote ne faisant par partie d'un radical nitro
C07D 413/14 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant au moins trois hétérocycles
THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Dow, Geoffrey S.
Smith, Bryan L.
Jones, John P.
Shmuklarsky, Moshe
Balasubrahmanyam, Budda
Abrégé
Methods of prevention of symptomatic malaria in a malaria-naïve, G6PD-normal human subject comprising administering to the human subject a compound of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I):
Methods of prevention of symptomatic malaria in a malaria-naïve, G6PD-normal human subject comprising administering to the human subject a compound of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I):
Methods of prevention of symptomatic malaria in a malaria-naïve, G6PD-normal human subject comprising administering to the human subject a compound of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I):
A compound of Formula (I) can be administered prior to potential exposure of a species of Plasmodium, during potential exposure of a species of Plasmodium, and after potential exposure of a species of Plasmodium. The methods of the invention also pertains to kits comprising specific doses of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I), and instructions for administration of dosing quantity and frequency. The methods of the invention also pertain to determining doses of Formula (I) that meet the general regulatory requirement for a drug to be efficacious in the prevention of malaria in malaria-naïve subjects. The methods of the invention further pertain to using the described algorithm to derive dosing regimens which can provide protection against symptomatic malaria in malaria-naïve, G6PD-normal subjects.
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (Royaume‑Uni)
THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (USA)
Inventeur(s)
Bavari, Sina
Kane, Christopher D.
Peat, Andrew James
Soloveva, Veronica
Abrégé
Provided are cathepsin inhibitor compounds and pharmaceutically acceptable salts thereof, and combinations thereof, for use in the treatment or prophylaxis of viral disease in an animal.
A61K 31/55 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p. ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p. ex. azélastine, pentylènetétrazole
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61P 31/14 - Antiviraux pour le traitement des virus ARN
69.
Mass spectrometry ionization based-assay for the detection of enzyme activity and/or presence
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Glaros, Trevor G
Dhummakupt, Elizabeth S
Mach, Phillip M
Carmany, Daniel O
Abrégé
An apparatus and method for detecting an analyte of interest using paper spray mass spectrometry includes a spray material; a sample on the spray material including an enzyme of interest; a solvent to hydrate the sample, promote enzymatic activity, and extract analytes of interest from the sample; a substrate specific to the enzyme of interest, wherein any of the spray material and the solvent includes the substrate; a voltage source to apply a voltage to the spray material to create charged droplets of a mixture containing the sample; and a mass spectrometer to perform spectrometry on the droplets to perform any of: identify the analytes of interest in the sample; and measure a level of inhibition in any enzymes contained in the sample.
C12Q 1/46 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase une estérase une cholinestérase
H01J 49/04 - Dispositions pour introduire ou extraire les échantillons devant être analysés, p. ex. fermetures étanches au videDispositions pour le réglage externe des composants électronoptiques ou ionoptiques
H01J 49/16 - Sources d'ionsCanons à ions utilisant une ionisation de surface, p. ex. émission thermo-ionique ou photo-électrique
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
70.
Weapon energy harvesting by gas turbine electric generator
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Smtih, Alexander
Hoffman, Brian
Colonnello, Michael
Abrégé
A power generation assembly for a weapon system converts waste energy from a firing event to electric power. The power generation assembly directs expanding burning propellant gasses within the weapon system into a turbine array to generate electric current. The electric current is rectified to trickle charge a battery bank which then powers the weapon system.
F41A 13/10 - Ventilateurs ou turbines pour l'évacuation des gaz ou le refroidissement des armes à feu, p. ex. actionnés par la pression des gaz de combustion ou le recul
F41A 19/08 - Systèmes de mise à feu mécaniques actionnés à distanceSystèmes de mise à feu mécaniques actionnés par un cordon tire-feu
71.
Fired cartridge case collectors and methods of use thereof
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Moore, Richard B.
Whittaker, David F
Wallace, Kevin S
Bille, Todd W
Peiffer, Gregory A
Weitz, Steven M
Abrégé
A fired cartridge case collector includes a base having a collection post. The collection post of the base is configured to collect and suspend a fired cartridge case without causing contact to an exterior surface of the fired cartridge case. The fired cartridge case collector also includes a protective envelope having a first end and a second end opposite the first end, wherein the first end of the protective envelope is configured to be removably secured to the base. The protective envelope is configured to prevent contact between an interior surface of the protective envelope and the exterior surface of the fired cartridge case while the protective envelope is removably secured to the base. The fired cartridge case collector permits individual collection, packaging, and non-contact storage of fired gun cartridge cases thereby preserving any DNA or other evidence that may be present.
GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Anderson, Michael Jeffrey
Walker, Jeremy Stephen
Dusenbury, Iv, James Saye
Abrégé
A portable filtration system is described. The system may comprise: a mixing portion, comprising: a pump adaptor and a contaminant regulator. The pump adaptor may comprise: an upper plate, a lower plate, and a screen. The screen may axially extend between the upper and lower plates, wherein the upper plate, the lower plate, and the screen define a channel of a mixing chamber. The contaminant regulator may comprise a through-passage coupled to the upper plate, wherein the through-passage is in fluid communication with the mixing chamber.
Government of the United States, as Represented by the Secretary of the Army (USA)
Inventeur(s)
Hart, Robert James
Smail, Andrew Quintin
Abrégé
A band track including a band having an inner surface, an outer surface, a first side face, and a second side face; a plurality of teeth extending from the inner surface and spaced apart circumferentially around the inner surface; a plurality of lugs extending from the outer surface and each spaced a distance apart circumferentially around the outer surface; a plurality of living hinges defined within the band circumferentially between each of the plurality of teeth; and at least one fiber-reinforcement disposed circumferentially within a neutral plane of the plurality of living hinges and a method of making the same.
High Performance Air Stable Solid Polymer Electrolyte (USA)
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Widstrom, Matthew D.
Kofinas, Peter
Cresce, Arthur V.
Xu, Kang
Abrégé
The present invention is directed to aqueous solid polymer electrolytes that comprise a lithium salt and battery cells comprising the same. The present invention is also directed to methods of making the electrolytes and methods of using the electrolytes in batteries and other electrochemical technologies.
H01M 10/0565 - Matériaux polymères, p. ex. du type gel ou du type solide
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p. ex. batteries à insertion ou intercalation de lithium dans les deux électrodesBatteries à l'ion lithium
H01M 4/58 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de composés inorganiques autres que les oxydes ou les hydroxydes, p. ex. sulfures, séléniures, tellurures, halogénures ou LiCoFyEmploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de structures polyanioniques, p. ex. phosphates, silicates ou borates
H01M 4/505 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de manganèse d'oxydes ou d'hydroxydes mixtes contenant du manganèse pour insérer ou intercaler des métaux légers, p. ex. LiMn2O4 ou LiMn2OxFy
H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
75.
Chemical detection training container and method for use thereof
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Riley, Patrick C
Hauck, Brian C
Abrégé
A sealable sampling container includes a vessel having a bottom and walls upwardly extending therefrom and terminating in a sealing surface, the bottom and the walls defining a volume within the open top container. A gasket is configured to engage with the sealing surface of the vessel and a lid is configured to engage with the gasket at the sealing surface and lock to the vessel. A sampling port is affixed to one side of the vessel or the lid, the sampling port providing fluid communication between the volume within the open top container and an external environment. The sealable sampling container safely stores volatile chemical vapors and enables training on use of chemical detection equipment without resort to ventilation hoods or the use of respiratory protection equipment.
The United States of America, as represented by the Secretary of the Army (USA)
Inventeur(s)
Duron, Christopher M.
Day, Gauge C.
Shrontz, Jessica L.
Taylor, Travis S.
Abrégé
A modular satellite chassis includes frame rails having at least two front frame rails and two back frame rails. Transverse parallel ribs are disposed on the interiors of the front and back frame rails. The ribs on the front frame rails correspond in location to one another and to the ribs on the back frame rails. Each rib has a central longitudinal axis and a narrow first slot disposed along the central longitudinal axis. The ribs are spaced apart by wider second slots. Trays are slidingly received by the second slots on the front frame rails and the corresponding second slots on the back frame rails. A left side panel is connected to an outside of one of the front frame rails and one of the back frame rails. A right side panel is connected to an outside of the other front frame rail and the other back frame rail.
The Government of the United States, as represented by the Secretary of the Army (USA)
Inventeur(s)
Doherty, Laurel A
Soares, Jason W
Arcidiacono, Steven
Pearce, Sarah
Abrégé
An in vitro model of an in vivo gastrointestinal tract including an in vitro model of an in vivo small intestine including a plurality of fermentation vessels and an in vitro model of an in vivo large intestine including a plurality of fermentation vessels is provided. A method of simulating a biotransformation of food product through the human digestive tract using an in vitro model of an in vivo gastrointestinal tract is provided.
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
C12N 5/071 - Cellules ou tissus de vertébrés, p. ex. cellules humaines ou tissus humains
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
C12M 1/40 - Appareillage spécialement destiné à l'utilisation d'enzymes libres, immobilisées ou liées à un support, p. ex. appareils contenant un lit fluidisé d'enzymes immobilisées
C12M 1/36 - Appareillage pour l'enzymologie ou la microbiologie comportant une commande sensible au temps ou aux conditions du milieu, p. ex. fermenteurs commandés automatiquement
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p. ex. par des compteurs de colonies
G01N 33/50 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique
C12M 1/02 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens d'agitationAppareillage pour l'enzymologie ou la microbiologie avec des moyens d'échange de chaleur
78.
BIOMARKERS AND IMMUNOGENIC COMPOSITIONS FOR FILARIAL PARASITES
The United States of America, as Represented by (USA)
Inventeur(s)
Lustigman, Sara
Nutman, Thomas B.
Bennuru, Sasisekhar
Abrégé
Disclosed herein are immunogenic compositions for preventing or treating infection with filarial parasites and biomarkers for diagnosing infection with filarial parasites.
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
C07K 16/18 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
Government of the United States as Represented by the Secretary of the Army (USA)
Inventeur(s)
Merrill, Haile A.
Abrégé
Apparel that is adjustable. For example, in one embodiment, the apparel is provided that includes a torso. The torso includes a front, a back, a first side connecting the front to the back, a second side connecting the front to the back, a bottom, and a top. A plurality of shell fabric portions is on the torso. Each portion in the plurality of portions of shell fabric is adapted to receive an elastomeric member. Bunched fabric is on the first side and second side of the torso. Pleats are on the front of the torso. A centrally located flap is on the torso and has a longitudinal axis that is substantially vertical. Sleeves are connected to the torso. A first zipper track is located on the bottom of the torso. Pants may include a second zipper track adapted to mate with the first zipper track and secure the pants to the torso.
The Government of the United States, as represented by the Secretary of the Army (USA)
Inventeur(s)
Rupper, Greg
Suarez, John
Rudin, Sergey
Reed, Meredith
Shur, Michael
Abrégé
Various embodiments are described that relate to failure determination for an integrated circuit. An integrated circuit can be tested to determine if the integrated circuit is functioning properly. The integrated circuit can be subjected to a specific radiation such that the integrated circuit produces a response. This response can be compared against an expected response to determine if the response matches the expected response. If the response does not match the expected response, then the integrated circuit fails the test. If the response matches the expected response, then the integrated circuit passes the test.
The Government of the United States, as Represented by the Secretary of the Army (USA)
Arcturus Therapeutics, Inc. (USA)
Inventeur(s)
Hooper, Jay W.
Mucker, Eric M.
Chivukula, Padmanabh
Abrégé
A nucleic acid vaccine composition comprising one or more of a plasmid-based nucleic acid vaccine and immunotherapy, as well as a lipid formulation, is provided. In addition, the present invention provides a method of enhancing the potency of plasmid-based DNA vaccines and immunotherapies, by formulating a vaccine and/or immunotherapy in a lipid formulation, which is stable when refrigerated or stored frozen, is then delivered to a vaccinee by either needle/syringe, jet injection, or microneedles. The lipid formulation of the present invention comprises one or more lipid excipients selected from 1,2-Distearoyl-sn-glycero-3-phosphocholine, Cholest-5-en-3β-ol, 1,2-Dimyristoyl-rac-glycero-3-methylpolyoxyethlene, and or more symmetric ionizable cationic lipids. The present invention increases vaccine potency dramatically. It was unexpectedly discovered that the level of immunogen, or immune response molecules, produced in vivo is increased (versus administering merely the vaccine or immunotherapy) and, in the case of a vaccine immunogen, the immune response is enhanced.
A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p. ex. par les adjuvants chimiques
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Hoffman, Brian
Smith, Alex
Colonnello, Michael
Binter, Eric
Abrégé
A remote weapon station (RWS) system for an unmanned ground vehicle (UGV) includes a dedicated weapon, multi-axis gimbal and ammunition handling capabilities with all operations functioning remotely and wirelessly. The RWS system is a gas powered, or self-powered, belt fed, rotating bolt lock weapon. In addition, the RWS is man-portable and air-droppable as the major subsystems may be latched together in the field without tooling or needing to make electrical connections.
GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Bamgboye, Olatunde O.
Bennett, Eric
Abrégé
A communication system provides multimedia communications within and between armored ground combat vehicles (GCVs). The system includes client computers within the armored GCVs providing distributed and interconnected multimedia communications among the client computers. The multimedia communication may include a one-to-one communication, a text communication to a group, an audio communication to a group, or a video communication to a group. Logic providing the distributed and interconnected multimedia communications is not located at a single client computer. The client computers display graphical user interfaces (GUIs) enabling soldiers to select parameters of the communication system with some GUIs providing presence discovery among the armored GCVs. One of the plurality of client computers acts as an origination station and other client computers may be configured as receiving communication station(s). The origination communication station may transmit digital communication data to the receiving communication station(s).
H04L 41/22 - Dispositions pour la maintenance, l’administration ou la gestion des réseaux de commutation de données, p. ex. des réseaux de commutation de paquets comprenant des interfaces utilisateur graphiques spécialement adaptées [GUI]
H04L 65/60 - Diffusion en flux de paquets multimédias
H04L 67/12 - Protocoles spécialement adaptés aux environnements propriétaires ou de mise en réseau pour un usage spécial, p. ex. les réseaux médicaux, les réseaux de capteurs, les réseaux dans les véhicules ou les réseaux de mesure à distance
H04L 69/326 - Protocoles de communication intra-couche entre entités paires ou définitions d'unité de données de protocole [PDU] dans la couche transport [couche OSI 4]
H04W 4/10 - Services de messagerie instantanée vocale ou de messagerie sur appel
84.
Full power blow-back gun with crash safety for lightweight application
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Smith, Alex
Brosseau, Tim
Michlin, Alex
Abrégé
A small lightweight weapon system for integration into an unmanned aerial vehicle comprises a weapon operating group which utilizes blowback operation to fire a full-powered centerfire rifle ammunition. An operating rod of the weapon operating group has an axis of translation offset from the longitudinal axis of the barrel thereby creating a moment couple on the system. A motor assembly controls the operation of the weapon operating group. Through a gear train, actuation of the motor assembly lifts a sear against a return torsion spring, which holds the operating group back when not firing. The gear train comprises a one way flywheel disconnect to increase the torque of the direct current motor and overcome the force of the torsion spring. Intelligent motor commutation and burst control are achieved through an encoder and software package.
F41A 7/08 - Mécanismes d'entraînement des armes à feu à moteur externe, c.-à-d. mécanismes d'entraînement pour déplacer le bloc de culasse pendant le tir automatique en utilisant une force externe
The Government of the United States, as represented by the Secretary of the Army (USA)
Inventeur(s)
Ghebrebrhan, Michael
Wetzel, Eric
Abrégé
The disclosed subject matter relates to relate to fibers, textiles, fabrics, clothing and methods that are retroreflective including fibers having a hollow sheath that is filled with retroreflective particles.
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Judson, John S.
Vankirk, Jessica K.
Senior, David V.
Ackerman, Craig R.
Duke, Daniel
Abrégé
Blast, ballistic, and entry resistant operable window systems include a sliding exterior glazing panel assembly, a sliding interior glazing panel assembly, an exterior frame assembly that receives the sliding exterior glazing panel assembly, an interior frame assembly that receives the sliding interior glazing panel assembly, an exterior gasket for placement between the exterior frame assembly and the wall of the building, a central gasket for placement between the exterior frame assembly and the interior frame assembly, and an interior gasket for placement between the interior frame assembly and the wall of the building. Methods of installation in a wall of a building are also provided.
E06B 5/12 - Portes, fenêtres ou fermetures analogues à buts particuliersStructures de cadrage à leur effet pour protection contre les raids aériens ou autres actes de guerrePortes, fenêtres ou fermetures analogues à buts particuliersStructures de cadrage à leur effet pour d'autres buts de protection contre la pression de l'air, les explosions ou les gaz
E06B 3/26 - Châssis composés, c.-à-d. comprenant un châssis dans ou derrière un autre châssis
E06B 3/54 - Fixation des vitres ou plaques analogues
E06B 3/64 - Fixation de plus d'une vitre au châssis
E06B 5/10 - Portes, fenêtres ou fermetures analogues à buts particuliersStructures de cadrage à leur effet pour protection contre les raids aériens ou autres actes de guerrePortes, fenêtres ou fermetures analogues à buts particuliersStructures de cadrage à leur effet pour d'autres buts de protection
E06B 5/11 - Portes, fenêtres ou fermetures analogues à buts particuliersStructures de cadrage à leur effet pour protection contre les raids aériens ou autres actes de guerrePortes, fenêtres ou fermetures analogues à buts particuliersStructures de cadrage à leur effet pour d'autres buts de protection contre les cambriolages
The United States of America as represented by the Secretary of the Army (USA)
Inventeur(s)
Borel-Donohue, Christoph C.
Abrégé
Methods, systems, and computer code on computer-readable media are provided that are directed to generating area skyline data using a digital elevation or surface models (DEMs or DESs) and shadow casting techniques. Some embodiments use an area of maximum shadow line overlap, for shadow line images based on target location skyline azimuth and elevation angle data, as the best approximation for the position of the target location in an area. Some embodiments select the location showing the best fit to the target skyline azimuth and elevation angle data as the best approximation for the target location.
The United States of America As Represented By the Secretary of The Army (USA)
Inventeur(s)
Sun, Zongxuan
Dong, Xiaonan
Goertemiller, Clifford Francis Webster
Kim, Kenneth Seong-Uk
Kweon, Chol-Bum Mike
Abrégé
In some examples, a method for estimating the cetane number of a fuel includes receiving current engine operating condition measurements from a compression ignition (CI) engine using the fuel, and determining a value for a current engine performance indicator. The method further includes determining a projected engine performance indicator value for the CI engine based on the current estimated cetane number, current engine control signals and the current engine operating condition measurements. The method also includes determining that a difference between the value of the current engine performance indicator and the projected engine performance indicator value is greater than a threshold amount. If the difference is greater than the threshold amount, the method also includes determining a new estimated cetane number.
G07C 5/08 - Enregistrement ou indication de données de marche autres que le temps de circulation, de fonctionnement, d'arrêt ou d'attente, avec ou sans enregistrement des temps de circulation, de fonctionnement, d'arrêt ou d'attente
89.
CLOT RETRACTION ASSAY FOR QUALITY MONITORING OF PLATELET PRODUCTS
THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Nair, Prajeeda M.
Cap, Andrew P.
Muraoka, Wayne T.
Bynum, James A.
Abrégé
This disclosure provides an assay and method for evaluating platelet function by measuring clot retraction in a grooved assay well using light transmittance in a low-volume, micro-plate formatted assay. The method takes advantage of the ability of platelets to draw the fibrin clot toward one side of the microplate well through an optical light path with readings recorded by a microplate reader. The method is rapid, tractable, has high precision, and yields time-series data that is quantitative. This allows clinicians and transfusion medicine practitioners to perform high throughput platelet function testing in patient samples and in blood/platelet products. Clot retraction serves as a functional biomarker to determine platelet function by performing the assay in a vessel that is scored to form a groove in which clot retraction occurs. Multiple samples can be tested simultaneously, and optionally an algorithm can be used to extract relevant parameters from the data.
G01N 33/86 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir le temps de coagulation du sang
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p. ex. verrerie de laboratoireCompte-gouttes
The United States of America as represented by the Secretary of the Army (USA)
Inventeur(s)
Mcintosh, Scotlund
Hepfinger, Lisa Bareiss
Stewardson, Cheryl Ann
Dugas, Anabela
Fairneny, James George
Abrégé
Camouflage patterns on a substrate such as a fabric comprise in a first aspect a substrate having a camouflage pattern with a set of intermixed colored blotches thereon, the colors of the set of intermixed colored blotches being selected from a group of colors comprising an Olive 527 color, a Dark Green 528 color, a Tan 525 color, a Brown 529 color, a Bark Brown 561 color and a Dark Cream 559 color. In another aspect the colors of the set of intermixed colored blotches being selected from a group of colors comprising an Olive 527 color, a Dark Green 528 color, a Light Sage 560 color, a Tan 525 color, a Brown 529 color, a Bark Brown 561 color and a Dark Cream 559 color.
The Government of the United States, as represented by the Secretary of the Army (USA)
Inventeur(s)
Lazzaro, Matthew
Toth, William
Abrégé
Various embodiments are described that relate to random noise addition to a communication. A first secure network can employ a first encryption scheme and a second secure network can employ a second encryption scheme. In order to communicate between the first secure network and the second secure network such that the schemes are not decipherable, random noise can be added to a communication designated to transfer from the first secure network to the second secure network.
THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Ruhl, Douglas Scott
Serra, Renee Makowski
Abrégé
A tongue blade (retractor) with fenestrated suction ports along the length of the blade to remove (suction) smoke, fluid and/or particulate from the oral cavity during surgery (e.g. tonsillectomy, adenoidectomy, oral cavity/tongue/airway procedures). This blade can connect to routine mouth retractors and commonly available suction tubing. It has a groove along the length of the blade to accommodate endotracheal tubes for stabilization and to minimize pressure against the tongue during retraction.
A61B 17/02 - Instruments, dispositifs ou procédés chirurgicaux pour maintenir les blessures ouvertes, p. ex. rétracteursÉcarteurs
A61B 1/267 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments pour les voies respiratoires, p. ex. laryngoscopes, bronchoscopes
A61B 1/015 - Commande de l'alimentation en fluide ou de l'évacuation de fluide
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p. ex. endoscopesDispositions pour l'éclairage dans ces instruments
B01D 46/00 - Filtres ou procédés spécialement modifiés pour la séparation de particules dispersées dans des gaz ou des vapeurs
B01D 29/52 - Filtres à éléments filtrants stationnaires pendant la filtration, p. ex. filtres à aspiration ou à pression, non couverts par les groupes Leurs éléments filtrants à plusieurs éléments filtrants caractérisés par leur agencement relatif montés en parallèle
B01D 37/02 - Revêtement préalable des éléments filtrants ou de la substance filtranteAddition d'adjuvants de filtration au liquide à filtrer
B01D 46/56 - Filtres ou procédés spécialement modifiés pour la séparation de particules dispersées dans des gaz ou des vapeurs avec plusieurs éléments filtrants, caractérisés par leur disposition relative
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (USA)
THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
UNIVERSITY OF MARYLAND, BALTIMORE (USA)
Inventeur(s)
Joyce, Michael Gordon
Modjarrad, Kayvon
Dooley, Helen
Hajduczki, Agnes
Chen, Wei-Hung
Abrégé
Disclosed herein are shark-derived antibodies and binding molecules with high binding affinity for SARS-CoV-2 coronavirus and the use thereof. Some of the shark-derived antibodies and binding molecules also demonstrate cross-reactivity with and neutralization of other related sarbecoviruses. The complementarity determining region (CDR) sequences and binding characteristics for these antibodies and binding molecules are provided. Also disclosed are the use of these antibodies and binding molecules to detect SARS-CoV-2 coronavirus or other related sarbecoviruses or to prevent or treat SARS-CoV-2 coronavirus or other related sarbecovirus infections.
C07K 16/10 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant de virus de virus à ARN
A61P 31/14 - Antiviraux pour le traitement des virus ARN
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
95.
BIOMARKERS OF IMMUNE DYSFUNCTION IN RESPONSE TO CHRONIC STRESS, METHODS OF USE AND DIAGNOSTIC KITS
The Government of the United States, as Represented by the Secretary of the Army (USA)
Inventeur(s)
Muhie, Seid
Jett, Marti
Hammamieh, Rasha
Abrégé
Diagnostic biomarkers for diagnosing immune suppression/dysfunction. The diagnostic biomarkers are genes and/or transcripts that are up or down regulated compared to normal expression when a subject has been stressed either mentally and/or physically. The invention also relates to a method of detecting compromised or suppressed immune response in a subject by comparing certain diagnostic biomarkers in the subject to a control set of diagnostic biomarkers.
C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p. ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
C12Q 1/6809 - Méthodes de détermination ou d’identification des acides nucléiques faisant intervenir la détection différentielle
C12Q 1/6837 - Couplage enzymatique ou biochimique d’acides nucléiques à une phase solide utilisant des réseaux de sondes ou des puces à sondes
THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Pierce, Bradley T.
Stevens, Ryan A.
Tilley, Laura C.
Abrégé
A thermogenic emergency airway management device configured to prevent or treat hypothermia in a patient. The device may be configured to receive inlet air and modify one or more properties of the inlet air to output air at a temperature and/or humidity associated with the prevention and/or treatment of hypothermia. In an embodiment, the device may receive input via a user interface to determine a temperature and/or humidity associated with the air to be output to the patient. In an embodiment, the input may additionally include an amount of air to be output to the patient. In such an embodiment, the device may be configured to cause the amount of air to be output to the patient to prevent and/or treat hypothermia.
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Ioannidis, Nikolaos
Ophir, Zohar
Panchal, Viral
Abbate, Philip
Sullivan, Francis
Young, Ming Wan
Gogos, Costas G.
Abrégé
The present invention is directed to a continuous process for producing a foamable celluloid product by introducing a solid component (comprising nitrocellulose, chemical blowing agent (CBA), stabilizer and alcohol) and a liquid component (comprising camphor and acetone) into a mixer/devolatilizer machine where the chamber is under atmospheric pressure and having significant overhead space. The chamber is comprised of two zones wherein the first zone has a temperature that is less than the second zone and at least one rotor comprising hollow, temperature-controlled arms having a tilted angle affixed to the rotors. The rotors of the mixer/devolatilizer machine act to mix the solid and liquid components under lower shearing forces, lower mechanical stress and longer residence times than those used by twin-screw extruders.
B29C 48/00 - Moulage par extrusion, c.-à-d. en exprimant la matière à mouler dans une matrice ou une filière qui lui donne la forme désiréeAppareils à cet effet
B29C 48/395 - Moyens pour plastifier ou homogénéiser la matière à mouler ou pour la forcer dans la filière ou la matrice utilisant des vis entourées par un fourreau coopérant, p. ex. des extrudeuses à vis simple
B29C 48/29 - Alimentation de l’extrudeuse en matière d’extrusion sous forme liquide
C08J 9/00 - Mise en œuvre de substances macromoléculaires pour produire des matériaux ou objets poreux ou alvéolairesLeur post-traitement
B01F 27/702 - Mélangeurs à agitateurs tournant dans des récipients fixesPétrins avec des agitateurs tournant autour d'un axe horizontal ou incliné avec des palettes, des lames ou des bras comprenant plusieurs arbres, p. ex. dans des chambres de mélange consécutives avec des palettes s’engrenant les unes dans les autres
B29K 1/00 - Utilisation de cellulose, de cellulose modifiée ou de dérivés de cellulose, p. ex. de viscose, comme matière de moulage
98.
Nano-structured alloy material and method of synthesizing
The United States of America as represented by the Secretary of the Army (USA)
Inventeur(s)
Darling, Kristopher A.
Hornbuckle, Billy C.
Fullenwider, Blake P.
Ostlind, Albert M.
Roberts, Anthony J.
Giri, Anit K.
Abrégé
A nano-structured alloy material includes a nanoparticle; a matrix phase surrounding the nanoparticle; and an alkali/alkali Earth metal to alter (i) a material property of the nanoparticle, (ii) a material property of the matrix phase, and (iii) an interaction of the nanoparticle with the matrix phase.
The United States of America as Represented by the Secretary of the Army (USA)
Inventeur(s)
Fancher, Charlie
Marlow, Bonnie L.
Nicolich, Kathryn
Backes, Kelly
Malvania, Neel
Cox, Kevin Christopher
Meyer, David Henry
Kunz, Paul D.
Hill, Joshua Cartwright
Holland, William Knox
Abrégé
A system for automatically locking a control laser in a Rydberg atomic sensor may comprise an atomic vapor cell, a probe laser configured to excite the atoms in the atomic vapor cell to an intermediate energy state, and a control laser configured to excite the one or more atoms in the atomic vapor cell from the intermediate energy state to a higher energy state. The light generated by the control laser may be dithered at a pre-determined frequency. The system further comprises a photodiode configured to convert light received from the vapor cell into an electrical signal, a lock-in amplifier configured to generate an error signal based on the electrical signal received from the photo diode and a received reference oscillation frequency, and a servo configured to receive the generated error signal from the lock-in amplifier and adjust a frequency of the control laser based on the received error signal.
Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (USA)
The Government of the United States, as Represented by the Secretary of the Army (USA)
Inventeur(s)
Joyce, Michael Gordon
Modjarrad, Kayvon
Abrégé
The present disclosure relates to the field of vaccines and binding molecules, as well as preparations and methods of their use in the treatment and/or prevention of disease. Described are vaccines and binding molecules, compositions containing the same, and uses thereof for treating or preventing coronavirus infections, in particular, β-coronaviruses such as SARS- CoV-2, the causative agent of COVID-19, as well as SARS-CoV-1 and other coronaviruses.