2015
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Invention
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Methods for the prevention and treatment of major adverse cardiovascular events using compounds t... |
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Invention
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Double strand compositions comprising differentially modified strands for use in gene modulation.... |
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Invention
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Compositions and methods for modulating angiopoietin-like 3 expression. Provided herein are metho... |
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Invention
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Modulation of apolipoprotein (a) expression.
Compounds, compositions and methods are provided fo... |
2014
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Invention
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5' and 2' bis-substituted nucleosides and oligomeric compounds prepared therefrom.
The present i... |
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Invention
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Oligomeric compounds comprising bicyclic nucleosides and having reduced toxicity.
In certain emb... |
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Invention
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Modulation of signal transducer and activator of transcription 3 (stat3) expression. Disclosed he... |
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Invention
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Compounds and methods for modulating apolipoprotein c-iii expression for improving a diabetic pro... |
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Invention
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Compositions and methods for modulation of target nucleic acids. The present disclosure pertains ... |
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Invention
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Compositions and methods for optimizing cleavage of rna by rnase h.
The present invention provid... |
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Invention
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Compounds and methods for modulating non-coding rna. Provided herein are antisense compounds and ... |
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Invention
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Chimeric oligomeric compounds comprising alternating regions of northern and southern conformatio... |
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Invention
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Compositions and methods for modulating apolipoprotein (a) expression. Provided herein are oligom... |
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Invention
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Compositions and methods for modulating apolipoprotein c-iii expression. Provided herein are olig... |
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Invention
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Compositions and methods. Provided herein are oligomeric compounds with conjugate groups. In cert... |
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Invention
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Conjugated antisense compounds and their use. Provided herein are oligomeric compounds with conju... |
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Invention
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Compositions and methods for modulating hbv and ttr expression. Provided herein are oligomeric co... |
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Invention
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Compositions and methods for modulation nucleic acids through nonsense mediated decay. Disclosed ... |
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Invention
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Compounds and methods for modulating expression apob.
The present disclosure describes short ant... |
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Invention
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Compositions and methods for modulating tau expression. Disclosed are methods for modulating spli... |
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Invention
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Modulation of inflammatory responses by c-reactive protein. Disclosed herein are compositions and... |
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Invention
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Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) po... |
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Invention
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Selective antisense compounds and uses thereof. The present disclosure provides oligomeric compou... |
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Invention
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Method off preparing oligomeric compounds. Provided herein are methods for the synthesis of oligo... |
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Invention
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Compositions and methods for modulation of smn2 splicing in a subject. Disclosed herein are compo... |
2013
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Invention
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Competitive modulation of micrornas. The present invention provides compounds and methods for com... |
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Invention
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Compositions and methods for in vivo delivery of antisense compounds. The present invention provi... |
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Invention
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Antisense compounds and uses thereof. The present invention provides compounds comprising oligonu... |
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Invention
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Cancer treatment. In certain embodiments, methods, compounds, and compositions for treating B-cel... |
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Invention
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Methods for modulating c9orf72 expression. Disclosed herein are methods for reducing expression o... |
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Invention
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Compositions for modulating c9orf72 expression. Disclosed herein are compositions and methods for... |
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Invention
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Methods for monitoring c9orf72 expression. Disclosed herein are methods for monitoring expression... |
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Invention
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Antisense compounds and uses thereof. The present disclosure provides oligomeric compounds. Certa... |
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Invention
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Modulation of androgen receptor expression. Certain embodiments are directed to compounds and com... |
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Invention
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Oligomeric compounds comprising bicyclic nucleosides and uses thereof. The present invention prov... |
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Invention
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Selective antisense compounds and uses thereof. The present invention provides oligomeric compoun... |
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Invention
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Methods of treating kennedy's disease. Certain embodiments are directed to methods of amelioratin... |
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Invention
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Modulation of copper related diseases by ctr1. Disclosed herein are antisense compounds and metho... |
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Invention
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Method of preparing oligomeric compounds using modified capping protocols. Provided herein are me... |
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Invention
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Combination therapy for the treatment of cancer. The present embodiments relate to combinations o... |
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Invention
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Modulation of renin-angiotensin system (ras) related diseases by angiotensinogen. Disclosed herei... |
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Invention
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Modulation of ube3a-ats expression. Certain embodiments are directed to methods and compounds for... |
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Invention
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Compounds and method for improved cellular uptake of antisense compounds. The present invention p... |
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Invention
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Antisense modulation of fibroblast growth factor receptor 4 expression. Antisense compounds, comp... |
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Invention
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Antisense compounds targeting genes associated with fibronectin. The present invention provides c... |
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Invention
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Antisense compounds targeting genes associated with fibronectin. Provided are compounds comprisin... |
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Invention
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Methods and compositions for modulating apolipoprotein(a) expression. Disclosed herein are antise... |
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Invention
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Modulation of enhancer rna mediated gene expression. Disclosed herein are methods and compounds f... |
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Invention
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Antisense compounds and methods of use thereof.
Disclosed herein are compounds, compositions and... |