Isis Pharmaceuticals, Inc.

United States of America

Create a watch for Isis Pharmaceuticals, Inc.
Total IP 208
Total IP Rank # 6,376
IP Activity Score 0/5.0    0
IP Activity Rank # 1,705,386

Patents

Trademarks

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Last Patent 2016 - Methods for the prevention and t...
First Patent 1984 - Method for inhibiting propagatio...

Latest Inventions, Goods, Services

2015 Invention Methods for the prevention and treatment of major adverse cardiovascular events using compounds t...
Invention Double strand compositions comprising differentially modified strands for use in gene modulation....
Invention Compositions and methods for modulating angiopoietin-like 3 expression. Provided herein are metho...
Invention Modulation of apolipoprotein (a) expression. Compounds, compositions and methods are provided fo...
2014 Invention 5' and 2' bis-substituted nucleosides and oligomeric compounds prepared therefrom. The present i...
Invention Oligomeric compounds comprising bicyclic nucleosides and having reduced toxicity. In certain emb...
Invention Modulation of signal transducer and activator of transcription 3 (stat3) expression. Disclosed he...
Invention Compounds and methods for modulating apolipoprotein c-iii expression for improving a diabetic pro...
Invention Compositions and methods for modulation of target nucleic acids. The present disclosure pertains ...
Invention Compositions and methods for optimizing cleavage of rna by rnase h. The present invention provid...
Invention Compounds and methods for modulating non-coding rna. Provided herein are antisense compounds and ...
Invention Chimeric oligomeric compounds comprising alternating regions of northern and southern conformatio...
Invention Compositions and methods for modulating apolipoprotein (a) expression. Provided herein are oligom...
Invention Compositions and methods for modulating apolipoprotein c-iii expression. Provided herein are olig...
Invention Compositions and methods. Provided herein are oligomeric compounds with conjugate groups. In cert...
Invention Conjugated antisense compounds and their use. Provided herein are oligomeric compounds with conju...
Invention Compositions and methods for modulating hbv and ttr expression. Provided herein are oligomeric co...
Invention Compositions and methods for modulation nucleic acids through nonsense mediated decay. Disclosed ...
Invention Compounds and methods for modulating expression apob. The present disclosure describes short ant...
Invention Compositions and methods for modulating tau expression. Disclosed are methods for modulating spli...
Invention Modulation of inflammatory responses by c-reactive protein. Disclosed herein are compositions and...
Invention Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) po...
Invention Selective antisense compounds and uses thereof. The present disclosure provides oligomeric compou...
Invention Method off preparing oligomeric compounds. Provided herein are methods for the synthesis of oligo...
Invention Compositions and methods for modulation of smn2 splicing in a subject. Disclosed herein are compo...
2013 Invention Competitive modulation of micrornas. The present invention provides compounds and methods for com...
Invention Compositions and methods for in vivo delivery of antisense compounds. The present invention provi...
Invention Antisense compounds and uses thereof. The present invention provides compounds comprising oligonu...
Invention Cancer treatment. In certain embodiments, methods, compounds, and compositions for treating B-cel...
Invention Methods for modulating c9orf72 expression. Disclosed herein are methods for reducing expression o...
Invention Compositions for modulating c9orf72 expression. Disclosed herein are compositions and methods for...
Invention Methods for monitoring c9orf72 expression. Disclosed herein are methods for monitoring expression...
Invention Antisense compounds and uses thereof. The present disclosure provides oligomeric compounds. Certa...
Invention Modulation of androgen receptor expression. Certain embodiments are directed to compounds and com...
Invention Oligomeric compounds comprising bicyclic nucleosides and uses thereof. The present invention prov...
Invention Selective antisense compounds and uses thereof. The present invention provides oligomeric compoun...
Invention Methods of treating kennedy's disease. Certain embodiments are directed to methods of amelioratin...
Invention Modulation of copper related diseases by ctr1. Disclosed herein are antisense compounds and metho...
Invention Method of preparing oligomeric compounds using modified capping protocols. Provided herein are me...
Invention Combination therapy for the treatment of cancer. The present embodiments relate to combinations o...
Invention Modulation of renin-angiotensin system (ras) related diseases by angiotensinogen. Disclosed herei...
Invention Modulation of ube3a-ats expression. Certain embodiments are directed to methods and compounds for...
Invention Compounds and method for improved cellular uptake of antisense compounds. The present invention p...
Invention Antisense modulation of fibroblast growth factor receptor 4 expression. Antisense compounds, comp...
Invention Antisense compounds targeting genes associated with fibronectin. The present invention provides c...
Invention Antisense compounds targeting genes associated with fibronectin. Provided are compounds comprisin...
Invention Methods and compositions for modulating apolipoprotein(a) expression. Disclosed herein are antise...
Invention Modulation of enhancer rna mediated gene expression. Disclosed herein are methods and compounds f...
Invention Antisense compounds and methods of use thereof. Disclosed herein are compounds, compositions and...