2019
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Invention
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Combination therapy for inducing immune response to disease.
The present invention concerns comp... |
2018
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Invention
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Murine, chimeric, humanized or human anti-tnf-alpha antibodies. The present invention concerns co... |
2017
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Invention
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Disease therapy by inducing immune response to trop-2 expressing cells. + cancer cells. The cytot... |
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Invention
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Multivalent antibody complexes targeting igf-1r show potent toxicity against solid tumors.
The p... |
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Invention
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Combination therapy for inducing immune response to disease. + cancer cells. The cytotoxic immune... |
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Invention
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Murine, chimeric, humanized or human anti-il-6 antibodies. The present invention concerns composi... |
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Invention
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Combination therapy with t-cell redirecting bispecific antibodies and checkpoint inhibitors. The ... |
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Invention
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T-cell redirecting bispecific antibodies for treatment of disease. The present invention concerns... |
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Invention
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Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-loc... |
2016
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Invention
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Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of... |
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Invention
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Dock-and-lock (dnl) complexes for therapeutic and diagnostic use.
Disclosed herein are methods a... |
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Invention
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Tetrameric cytokines with improved biological activity. The present invention concerns methods an... |
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Invention
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Combination therapy for inducing immune response to disease. The present invention concerns combi... |
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Invention
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Compositions and methods of use of immunotoxins comprising ranpirnase (rap) show potent cytotoxic... |
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Invention
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Pegylation by the dock and lock (dnl) technique. The present invention concerns methods and compo... |
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Invention
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Dock-and-lock (dnl) vaccines for cancer therapy.
The present invention concerns methods and comp... |
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Invention
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Multimeric complexes with improved in vivo stability, pharmacokinetics and efficacy.
The present... |
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Invention
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Bispecific antibodies that neutralize both tnf-alpha and il-6: novel therapeutic agent for autoi... |
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Invention
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Immunoconjugates with an intracellularly-cleavable linkage. The invention relates to therapeutic ... |
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Invention
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Combination therapy with anti-cd74 and anti-cd20 antibodies provides enhanced toxicity to b-cell ... |
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Invention
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T-cell redirecting bispecific antibodies for treatment of disease.
The present invention concern... |
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Invention
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Interferon lambda-antibody complexes. The present invention concerns methods and compositions for... |
2015
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Invention
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Dock-and-lock (dnl) constructs for human immunodeficiency virus (hiv) therapy. The present invent... |
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Invention
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Methods and compositions for generating bioactive assemblies of increased complexity and uses.
T... |
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Invention
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Disease therapy by inducing immune response to trop-2 expressing cells. The present invention con... |
2014
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Invention
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Bispecific antibodies that neutralize both tnf-α and il-6: novel therapeutic agent for autoimmune... |
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Invention
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Bispecific antibodies that neutralize both tnf-alpha and il-6: novel therapeutic agent for autoim... |
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Invention
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Stably tethered structures of defined compositions with multiple functions or binding specificiti... |
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Invention
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Multivalent antibody complexes targeting igf-1r show potent toxicity against solid tumors. The pr... |
|
Invention
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Dock-and-lock (dnl) complexes for therapeutic and diagnostic use. Disclosed herein are methods an... |
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Invention
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Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enh... |
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Invention
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Methods and compositions for generating bioactive assemblies of increased complexity and uses. Th... |
2013
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Invention
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Novel strategies for improved cancer vaccines.
The present invention concerns methods and compos... |
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Invention
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Combination therapy with anti-cd74 antibodies provides enhanced toxicity to malignancies, autoimm... |
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Invention
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Multimeric complexes with improved in vivo stability, pharmacokinetics and efficacy. The present ... |