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2025
|
Invention
|
Use of glutamate modulating agents with immunotherapies to treat cancer.
Disclosed are methods o... |
|
|
Invention
|
Methods of use for kv7 channel activators.
Provided herein are compounds and pharmaceutical comp... |
|
|
Invention
|
Riluzole prodrugs and their use.
Pharmaceutical compositions of the invention include substitute... |
|
|
Invention
|
Pyrazolyl compounds as kv7 channel activators.
Provided herein are optionally substituted pyrazo... |
|
|
Invention
|
Bifunctional degraders of galactose-deficient immunoglobulins.
A composition of matter including... |
|
2024
|
Invention
|
Sublingual formulation of riluzole.
Disclosed is sublingual administration of riluzole. In parti... |
|
|
Invention
|
Acyl benzo[d]thiazol-2-amine and their methods of use.
Disclosed are acyl benzo[d]thiazol-2-amin... |
|
2023
|
Invention
|
Benzoimidazol benzomidazol-1,2-yl amides as kv7 channel activators. Optionally substituted benzoi... |
|
|
Invention
|
Prodrugs of riluzole and their method of use.
Pharmaceutical compositions of the invention inclu... |
|
|
Invention
|
Riluzole prodrugs and their use. Pharmaceutical compositions of the invention include substituted... |
|
|
Invention
|
Use of riluzole prodrugs to treat ataxias. Disclosed are methods of treating ataxia by administer... |
|
|
Invention
|
Use of riluzole prodrugs to treat ataxias.
Disclosed are methods of treating ataxia by administe... |
|
|
Invention
|
Methods of treating glioblastoma with prodrugs of riluzole.
Provided is a method of treating gli... |
|
|
Invention
|
Kv7 channel activators compositions and methods of use. Provided herein are optionally substitute... |
|
|
Invention
|
Indolizine derivatives for treating trpm3-mediated disorders.
The invention relates to compounds... |
|
|
Invention
|
Pyrazolo[1,5-a]pyridine derivatives for treating trpm3-mediated disorders.
The invention relates... |
|
|
Invention
|
Indazole derivatives for treating trpm3-mediated disorders.
The invention relates to compounds t... |
|
|
Invention
|
New derivatives for treating trpm3 mediated disorders.
The invention relates to compounds that a... |
|
|
Invention
|
Pyrazolyl compounds as kv7 channel activators. Provided herein are optionally substituted pyrazol... |
|
|
Invention
|
Pyrazolo[1,5-a]pyridin-2,3-yl amides as kv7 channel activators.
Compounds such as those represen... |
|
|
Invention
|
Pyrazolo[1,5-a]pyridin-2,3-yl amides as kv7 channel activators. Pyrazolo[1,5-a]pyridin-2,3-yl ami... |
|
2022
|
Invention
|
Conjugated antibodies for treating diseases.
An agent including a human plasma immunoglobulin mo... |
|
|
Invention
|
Conjugated antibodies for treating diseases. An agent including a human plasma immunoglobulin moi... |
|
|
Invention
|
Use of riluzole, riluzole prodrugs or riluzole analogs with immunotherapies to treat cancers.
Di... |
|
|
Invention
|
Antibody drug conjugates using mates technology for delivering cytotoxic agents.
Among other thi... |
|
|
Invention
|
Agents for directed conjugation techniques and conjugated products.
Among other things, the pres... |
|
|
Invention
|
Compositions including conjugated therapy enhancers.
A composition including a first compound ha... |
|
|
Invention
|
Bifunctional degraders of galactose-deficient immunoglobulins.
An agent including a glycan-speci... |
|
|
Invention
|
Small molecules that bind to tdp-43 for the treatment of als and related disorders.
The present ... |
|
|
Invention
|
Technologies for preventing or treating infections.
Among other things, the present disclosure p... |
|
|
Invention
|
Use of riluzole prodrugs to treat alzheimer's disease.
Disclosed are methods of treating a patie... |
|
2021
|
Invention
|
Compositions and methods for treating obsessive-compulsive disorder.
Disclosed herein is a metho... |
|
|
Invention
|
Topical formulations of (1s)-1-phenyl-2-pyridin-2-ylethanamine.
Provided is a pharmaceutical for... |
|
|
Invention
|
Process for the preparation of verdiperstat.
An improved process for preparing verdiperstat is d... |
|
|
Invention
|
Method of treating amyotrophic lateral sclerosis with myeloperoxidase inhibitor.
Provided is a m... |
|
2020
|
Invention
|
Prodrugs of myeloperoxidase inhibitors.
Disclosed are prodrugs of myeloperoxidase (MPO) inhibito... |
|
|
Invention
|
Cd38-binding agents and uses thereof.
Among other things, the present disclosure provides compou... |
|
|
Invention
|
Prodrugs of riluzole and their method of use. Pharmaceutical compositions of the invention includ... |
