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2024
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Invention
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Modulators of chromosome 9 open reading frame 72 gene expression and uses thereof.
The present d... |
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Invention
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T cell modifying compounds and uses thereof.
Methods and compositions for modifying T-cells in w... |
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Invention
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Engineered blood brain barrier penetrant aav capsids. This application relates to engineering AAV... |
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Invention
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Fitness maturation of engineered aav capsid stac-102. This application relates to engineering AAV... |
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Invention
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Zinc finger protein transcription factors for repressing nav1.7 expression. The present disclosur... |
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Invention
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Engineering aav.
The present disclosure provides methods and compositions to develop AAV capsids... |
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Invention
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Methods and compositions for the treatment of rare diseases.
The present disclosure is in the fi... |
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2023
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Invention
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Engineered target specific nucleases.
Described herein are engineered nucleases comprising mutat... |
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Invention
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Assays for lysosomal storage diseases. The disclosure provides the methods of detecting an anti-l... |
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Invention
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Methods and compositions for treating huntington's disease.
Disclosed herein are compositions co... |
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Invention
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Compositions and methods for producing recombinant aav.
Provided herein are nucleic acid constru... |
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Invention
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Methods and compositions for modification of a cystic fibrosis transmembrane conductance regulato... |
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Invention
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Methods for the treatment of beta-thalassemia.
Described herein are methods and compositions for... |
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Invention
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Serine recombinase systems for site-specific gene editing. The present disclosure provides engine... |
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2022
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Invention
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Novel zinc finger fusion proteins for nucleobase editing. Provided herein are base editor systems... |
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Invention
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Methods and compositions for nuclease-mediated targeted integration of transgenes into mammalian ... |
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Invention
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Genetic modification of cytokine inducible sh2-containing protein (cish) gene.
The present discl... |
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Invention
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Methods and compositions for treatment of a genetic condition.
Methods and compositions for a ge... |
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Invention
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Methods for use of viral vector constructs for the treatment of fabry disease.
The present discl... |
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Invention
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Methods for use of viral vector constructs for the treatment of fabry disease. The present disclo... |
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Invention
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Methods and compositions for the treatment of neurologic disease.
Nucleases and methods of using... |
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Invention
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Targeted disruption of t cell and/or hla receptors.
Disclosed herein are methods and composition... |
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Invention
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Tau modulators and methods and compositions for delivery thereof.
The present disclosure is in t... |
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Invention
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Targeted disruption of t cell receptor genes using engineered zinc finger protein nucleases.
Dis... |
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Invention
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Mog-binding proteins and uses thereof. The present invention relates to the development of a nove... |
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Invention
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Mog-binding proteins and uses thereof. e.g., e.g., antibody or fragment thereof) capable of bindi... |
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Invention
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Liver-specific constructs, factor viii expression cassettes and methods of use thereof.
Describe... |
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Invention
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Methods for the treatment of sickle cell disease. Disclosed herein are ex vivo methods and compos... |
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Invention
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Antigen binders specific for il-23r and uses thereof. IL23R overexpression has been described as ... |
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Invention
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Ciita targeting zinc finger nucleases.
Disclosed herein are zinc finger nucleases for cleaving a... |
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Invention
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Methods and compositions for modulating pd1.
Disclosed herein are methods and compositions for m... |
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2021
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Invention
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Improved pharmaceutical compositions containing adeno-associated viral vector.
The present inven... |
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Invention
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Generation of cd4+ effector and regulatory t cells from human pluripotent stem cells.
Provided h... |
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Invention
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Novel zinc finger protein transcription factors for repressing alpha-synuclein expression.
The p... |
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Invention
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Methods of detecting anti-aav antibodies.
The disclosure relates to total antibody assays, inclu... |
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Invention
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Assays for fabry disease treatment.
The disclosure provides the enzyme and non-enzyme replacemen... |
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Invention
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Zinc finger fusion proteins for nucleobase editing.
Provided herein are base editor systems comp... |
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Invention
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Methods and compositions for expressing phenylalanine hydroxylase.
The present disclosure provid... |
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Invention
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Zinc finger protein transcription factors for repressing tau expression.
The present disclosure ... |
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2020
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Invention
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Novel compositions and methods for producing recombinant aav.
Provided herein are nucleic acid c... |
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Invention
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Compositions and methods for genome engineering.
The present disclosure provides push-pull donor... |
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Invention
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Zinc finger nuclease variants for treating or preventing lysosomal storage diseases.
The present... |
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Invention
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Zinc finger protein transcription factors for treatment of prion disease.
The present disclosure... |
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2016
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G/S
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Biochemicals, namely, engineered proteins for the regulation of human, animal, plant, viral and m... |
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2010
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G/S
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Medical and scientific research and development, clinical testing, and consultation related there... |
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2002
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G/S
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Chemicals used in industry, science and photography, as well as in agriculture, horticulture and ... |
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2001
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G/S
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Engineered proteins that regulate the genetic transcription process for use in pharmaceutical res... |
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G/S
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DNA binding proteins for the regulation of human, plant and microbial genes for use in pharmaceut... |
