Whitehead Institute for Biomedical Research

United States of America

 
Total IP 319
Total IP Rank # 4,062
IP Activity Score 3/5.0    141
IP Activity Rank # 4,888

Patents

Trademarks

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152 0
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Last Patent 2025 - Reprogramming of somatic cells
First Patent 1985 - Transmissible, mammalian genes a...

Latest Inventions, Goods, Services

2025 Invention Regulation of transcription through ctcf loop anchors. Disclosed are methods of altering express...
2024 Invention Imaging-based pooled genetic screens with highly multiplexed phenotypes. The present disclosure g...
Invention Reprogramming of somatic cells. The disclosure relates to a method of reprogramming one or more ...
Invention Trigger nucleic acids and rna-binding proteins for upregulating gene expression. The present dis...
Invention Trigger nucleic acids and rna-binding proteins for upregulating gene expression. The present disc...
Invention Compositions and methods for making epigenetic modifications. The disclosure provides, in variou...
Invention Compositions and methods for generating genomic structural variation in plants. Provided herein a...
Invention Methods of editing dna methylation. The invention relates to methods of modifying DNA methylatio...
Invention Labeling of antibodies. Provided herein are methods for producing site specific PEG modification...
Invention Methods for reprogramming somatic cells. The invention provides methods for reprogramming somati...
Invention Compositions and methods for making epigenetic modifications. The disclosure provides, in various...
Invention Compositions and methods for making epigenetic modifications. e.g.e.g.e.g., a human) in need ther...
Invention Single-domain antibodies directed against gasdermin d and their use. The present invention is con...
2023 Invention Methods of altering gene expression by perturbing transcription factor multimers that structure r...
Invention Chromosome neighborhood structures and methods relating thereto. Work described herein reveals 3...
Invention Engineered macrophages for use in treating cancer. The present disclosure relates to pharmaceutic...
Invention Compositions and methods for treating cancer with interferon-omega and analogs thereof. The prese...
Invention Combination of macrophage-directed immunotherapy and cytokines for treatment of cancer. The prese...
Invention Enzymatic synthesis of kavalactones and flavokavains. Disclosed are methods, compositions, prote...
Invention Regulation of transcription through ctcf loop anchors. Disclosed are methods of altering expressi...
Invention Antiparasitic agents and methods. Methods of reducing viability of a parasite in a subject involv...
Invention Rna-binding by transcription factors. Expression of a target gene is modulated by an agent that m...
Invention Methods and systems for quantifying partitioning of agents in vivo based on partitioning of agent...
Invention In vitro. Small molecule therapeutics can concentrate in distinct intracellular environments, som...
Invention Methods and compositions for treating a premature stop codon-mediated disorder. Modified tRNAs c...
Invention Compositions and methods for mammalian genetics and uses thereof. The invention provides composi...
Invention Compositions and methods of a high-throughput screen to identify compounds that alter macrophage-...
Invention The combination of macrophage-directed immunotherapy and targeted agents for treatment of cancer....
Invention Nanobody based imaging and targeting of ecm in disease and development. Methods for developing d...
Invention Innate immune checkpoint modulators. Provided herein are compositions and methods of modulating ...
Invention Innate immune checkpoint modulators. Provided herein are compositions and methods of modulating m...
2022 Invention Wnt pathway stimulation in reprogramming somatic cells with nuclear reprogramming factors. The i...
Invention Ribosomal biosynthesis of moroidin peptides in plants. An alternative route to moroidin-type bic...
Invention Ribosomal biosynthesis of moroidin peptides in plants. An alternative route to moroidin-type bicy...
Invention Uses of rhodoquinone for the treatment of disease. Provided herein are compounds of Formulae (I)...
Invention Uses of rhodoquinone for the treatment of disease. Provided herein are compounds of Formulae (I) ...
Invention Methods and agents for decreasing insulin resistance. Disclosed herein are methods and agents fo...
Invention Human plasma-like medium. In some aspects, described herein are cell culture media that are usef...
Invention Cdc20 variants resistant to anti-mitotic drugs and related methods and compositions. Disclosed a...
Invention Methods for labeling and targeting cells. Disclosed herein are compositions and methods for labe...
Invention Methods of editing dna methylation. The invention relates to methods of modifying DNA methylation...
Invention Methods and compositions for efficient production of biofuels and bioplastics from toxic feedstoc...
Invention Compositions and methods for production of salidroside, icariside d2, and precursors of salidrosi...
2021 Invention Modulating transcriptional condensates. Disclosed herein are methods of modulating condensate de...
Invention Methods of modulating sex ratio. Disclosed herein are compositions, methods, and transgenic anim...
Invention Viral condensates and methods of use thereof. Provided herein are methods of screening for agent...
Invention The kinase nek10 and its use in treating and diagnosing bronchiectasis and other respiratory diso...
2020 Invention Overlapping therapeutic strategies for cystinosis treatment and cosmetic skin darkening. Disclos...