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2023
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Invention
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Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith.
Pro... |
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2022
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Invention
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Treatment of cancer with tor kinase inhibitors.
Provided herein are methods for treating or prev... |
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Invention
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Substituted diaminocarboxamide and diaminocarbonitrile pyrimidines, compositions thereof, and met... |
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Invention
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Pyrazino[2,3-b]pyrazine mtor kinase inhibitors for oncology indications and diseases associated w... |
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2021
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Invention
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Solid forms of 2-(tert-butylamino)-4-((1r,3r,4r)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-... |
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Invention
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Isotopologues of 2-(tert-butylamino)-4-((1r,3r,4r)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-... |
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Invention
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Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith. Prov... |
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2020
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Invention
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Substituted pyrazino[2,3-b]pyrazines as mtor kinase inhibitors. Provided herein are Heteroaryl Co... |
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2019
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Invention
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Methods for treating cancer using tor kinase inhibitor combination therapy.
Provided herein are ... |
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Invention
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Isotopologues of 2-(tert butylamino)-4-((1r,3r,4r)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-... |
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2018
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Invention
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Formulations of 2-(tert-butylamino)-4-((1r,3r,4r)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5... |
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Invention
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Solid forms of (1s,4s)-4-(2-(((3s,4r)-3-fluorotetrahydro-2h-pyran-4-yl)amino)-8-((2,4,6-trichloro... |
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Invention
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Pharmaceutical compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-(trans)-4-methoxycycloh... |
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Invention
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Methods for treating cancer using dihydropyrazino-pyrazine compound combination therapy. Provided... |
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Invention
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Treatment of cancer with tor kinase inhibitors. Provided herein are methods for treating or preve... |
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2017
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Invention
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Pharmaceutical formulations, processes, solid forms and methods of use relating to 1-ethyl-7-(2-m... |
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Invention
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H)-one, a solid form there of and methods of their use. Provided herein are compositions of 7-(6-... |
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Invention
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Formulations of 2-(tert-butylamino)-4-((1r,3r,4r)-3-hydroxy-4methylcyclohexylamino)-pyrimidine-5-... |
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Invention
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Substituted pyrazino[2,3-b]pyrazines as mtor kinase inhibitors. Provided herein are methods for t... |
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Invention
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Methods for treating cancer using tor kinase inhibitor combination therapy comprising administeri... |
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Invention
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Solid forms of (1s,4s)-4-(2-(((3s4r)-3-fluorotetrahydro-2h-pyran-4-yl) amino)-8-((2,4,6-trichloro... |
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Invention
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Treatment of cancer with dihydropyrazino-pyrazines. Provided herein are methods for treating or p... |
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Invention
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Methods of treating a cancer using substituted pyrrolopyrimidine compounds, compositions thereof.... |
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Invention
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Pharmaceutical compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclo... |
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2016
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Invention
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Methods for measurement of inhibition of c-jun n-terminal kinase in skin. Provided herein are met... |
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Invention
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Solid forms of 1-ethyl-7-(2-methyl-6-(1h-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino [2,... |
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Invention
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Solod forms 4-((4-(cyclopentyloxy)-5-(2-methylbenzo[d] oxazol-6-yl)17h-pyrrolo[2,3-d]pyrimidin-2-... |
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Invention
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Methods of treatment using substituted diaminopyrimidyl compounds. Provided herein are uses of di... |
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Invention
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Modulation of stem cell and progenitor cell differentiation, assays, and uses thereof.
The prese... |
