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2021
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Invention
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Solid forms of 1-(5-(3-(7-(3-fluorophenyl)-3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyrid... |
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2020
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Invention
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Methods of treating cartilage disorders through inhibition of clk and dyrk. Provided herein are m... |
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Invention
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Pyrazole derivatives as modulators of the wnt/b-catenin signaling pathway. Pyrazole compounds (I)... |
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2019
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Invention
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Indazole containing macrocycles and therapeutic uses thereof. Indazole macrocycle compounds of fo... |
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Invention
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B- and y -diketones and y -hydroxyketones as wnt/ b -catenin signaling pathway activators.
The p... |
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Invention
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1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof.
Provided herein are compounds accordin... |
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Invention
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5-heteroaryl substituted indazole-3-carboxamides and preparation and use thereof. Indazole compou... |
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2018
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Invention
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3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof.
Azaindazol... |
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Invention
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Diazanaphthalen-3-yl carboxamides and preparation and use thereof. Diazanaphthalene compounds for... |
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Invention
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6-(5-membered heteroaryl)isoquinolin-3-yl-(5-membered heteroaryl) carboxamides and preparation an... |
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Invention
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6-(6-membered heteroaryl & aryl)isoquinolin-3-yl carboxamides and preparation and use thereof. Is... |
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Invention
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6-(5-membered heteroaryl)isoquinolin-3-yl carboxamides and preparation and use thereof. Isoquinol... |
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2017
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Invention
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Single-dose, ready-to-use injectable formulations. Provided are single-dose, ready-to-use formula... |
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Invention
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Methods of using indazole-3-carboxamides and their use as wnt/b-catenin signaling pathway inhibit... |
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Invention
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Process for preparing n-(5-(3-(7-(3-fluorophenyl)-3h-imidazo[4,5-c]pyridin-2-yl)-1h-indazol-5-yl)... |
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Invention
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Isoquinolin-3-yl carboxamides and preparation and use thereof. Isoquinoline compounds for treatin... |
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2016
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Invention
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2-(1h-indazol-3-yl)-3h-imidazo[4,5-c]pyridines and their anti-inflammatory uses thereof. Indazole... |
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Invention
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Treatment of osteoarthritis. Provided are compositions and methods for treating osteoarthritis in... |
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Invention
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3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof. 4-Aza... |
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Invention
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3-(1h-pyrrolo[2,3-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof. 6-Aza... |
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Invention
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3-(1h-pyrrolo[2,3-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof. 7-Aza... |
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Invention
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3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof. 7-Aza... |
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Invention
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3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof. 4-Aza... |
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Invention
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3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof. 4-Azaindaz... |
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Invention
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3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof. 4-Aza... |
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Invention
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3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof. Indazole compounds f... |
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Invention
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3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof. Indazole compounds f... |
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Invention
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3-(1h-indol-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof. 6-Azaindazole compoun... |
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Invention
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3-(1h-indol-2-yl)-1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof. 7-Azaindazole compoun... |
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Invention
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3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof. 6-Aza... |
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Invention
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3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof. 6-Aza... |
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Invention
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3-(1h-indol-2-yl)-1h-indazoles and therapeutic uses thereof. Indazole compounds for treating vari... |
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Invention
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3-(1h-indol-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof. 4-Azaindazole compoun... |
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Invention
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3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof. 7-Aza... |
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Invention
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3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof. 4-Aza... |
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Invention
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3-(1h-pyrrolo[2,3-c]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof. Indazole compounds f... |
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Invention
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3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof. 4-Aza... |
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2015
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Invention
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2-(1h-indazol-3-yl)-1h-imidazo[4,5-c]pyridine and therapeutic uses thereof. Indazole compounds fo... |
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Invention
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3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof. Azaind... |
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Invention
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2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof. Indazole compounds fo... |
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Invention
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3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof. Azaind... |
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Invention
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3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof. Azaind... |
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Invention
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3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof. Azaindazole... |
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Invention
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3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof. Azaind... |
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Invention
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3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof. Azaind... |
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Invention
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Gamma-diketones for treatment and prevention of aging skin and wrinkles. The present disclosure r... |
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Invention
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5-substituted indazole-3-carboxamides and preparation and use thereof. Indazole compounds for tre... |
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2014
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Invention
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Gamma-diketones as wnt/beta -catenin signaling pathway activators. The present disclosure provide... |
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Invention
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3-(benzoimidazol-2-yl)-indazole inhibitors of the wnt signaling pathway and therapeutic uses ther... |
