The invention relates to a feeding device (1) for feeding small parts, in particular closure elements, comprising a vibrating spiral conveyor (20) having an outlet (200), a feed rail (20), which is arranged downstream of the outlet in the feed direction, and a vibratory drive (201, 211, 221), wherein, by means of the vibratory drive (201, 211, 212), vibrations can be applied to the vibrating spiral conveyor (20) to move the small parts in the direction of the outlet (200) and to the feed rail (21) to move the small parts along the feed rail (21), wherein an intermediate rail (22) is arranged between the outlet (200) of the vibrating spiral conveyor (20) and the feed rail (21), wherein vibrations can be applied to the intermediate rail (22) by means of the vibratory drive (201, 211, 221) to move the small parts along the intermediate rail (22) in the direction of the feed rail (21), wherein a monitoring device (3), associated with the intermediate rail (22), is provided, wherein the monitoring device (3) is designed to detect an abnormality and/or disturbance in the movement of the small parts along the intermediate rail (22), and wherein the feeding device is designed to temporarily interrupt the application of vibrations to the intermediate rail (22) and to the vibrating spiral conveyor (20) to rectify an abnormality and/or disturbance without interrupting the application of vibrations to the feed rail (21) for moving the small parts along the feed rail (21). The invention further relates to a method for feeding small parts.
B65G 47/14 - Devices for feeding articles or materials to conveyors for feeding articles from disorderly-arranged article piles or from loose assemblages of articles arranging or orientating the articles by mechanical or pneumatic means during feeding
B65G 27/02 - Jigging conveyors comprising helical or spiral channels or conduits for elevation of materials
The invention relates to a method and a device for unpacking a plurality of containers packed together in a shrink film and combined to form a package having at least two rows, wherein the shrink film has an upper side, which is associated with openings of the containers, and an opposite lower side, wherein the package (1) is provided in such a way that the upper side (100) of the shrink film (10) points downwards, and/or wherein, after or during opening of the shrink film (10), a frame (240) is placed around the opened package (1), said frame surrounding the opened package (1).
The invention relates to a device (2) and a method for filling a plurality of containers (1) in a nest (10) comprising columns (101) and rows (102), in particular for filling nested ampoules or carpules, wherein a container positioned in a column (101) is filled with a filling needle (200), the container (1) to be filled in the column (101) is lifted out of the nest (10) by a lifting device (24) before the filling process and/or during the filling process, and the container (1) to be filled is secured against tilting on the lifting device (24) during the lifting process.
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 3/30 - Methods or devices for controlling the quantity of the material fed or filled by volumetric measurement
B65B 57/14 - Automatic control, checking, warning or safety devices responsive to absence, presence, abnormal feed, or misplacement of articles or materials to be packaged and operating to control, or stop, the feed of articles or material to be packaged
B65B 3/26 - Methods or devices for controlling the quantity of the material fed or filled
B65B 43/59 - Means for supporting containers or receptacles during the filling operation vertically movable
B65B 39/12 - Nozzles, funnels or guides for introducing articles or materials into containers or wrappers movable towards, or away from, container or wrapper during filling or depositing
B65B 7/16 - Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
B65B 7/28 - Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
B65B 55/02 - Sterilising, e.g. of complete packages
The invention relates to a method and a device (2) for filling a plurality of containers (1) in a nest (10) comprising columns (101) and rows (102), in particular for filling nested ampoules or cartridges, wherein a plurality, in particular all, of the containers arranged in a column (101) are each simultaneously filled by way of a filling needle (200), wherein a sensor device (21) in each case detects when a defined fill level is reached during the filling operations of the containers (1), and wherein detection of the defined fill level being reached triggers a stop signal for the filling operation of the respective container (1).
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 3/30 - Methods or devices for controlling the quantity of the material fed or filled by volumetric measurement
B65B 43/54 - Means for supporting containers or receptacles during the filling operation
B65B 57/14 - Automatic control, checking, warning or safety devices responsive to absence, presence, abnormal feed, or misplacement of articles or materials to be packaged and operating to control, or stop, the feed of articles or material to be packaged
The invention relates to a device and a method for ensuring the sterilization of objects, products, and/or components which contact objects and/or products in a clean room, wherein an air flow is provided in the clean room over a component (20, 30), which is arranged in the clean room, and to an object, a product, and/or a component which contacts the object and/or product. A cover (10) made of a sterilizable material, in particular a material which can be autoclaved, can be arranged on the component (20, 30) or upstream of the component (20, 30) such that a contamination of the air flow being guided over the component (20, 30) is prevented on the component (20) by means of the cover (10). The invention additionally relates to the use of a cover (10) in order to ensure sterilization of objects in a clean room.
The invention relates to a method and a device for finding objects (2, 3, 4, 5) in a filling and/or sealing and/or post-processing installation, in particular for the pharmaceutical industry, before a decontamination cycle, before start of production and/or after an end of production, wherein a camera system (10) is used to record an image of a region (6) of the filling and/or sealing and/or post-processing installation, and wherein, on the basis of the image, an artificial intelligence model (AI model) (120) trained to identify the objects (2, 3, 4, 5) is used to check whether an object (2, 3, 4, 5) is present in the region (6) of the filling and/or sealing and/or post-processing installation. The invention also relates to a computer program for finding objects (2, 3, 4, 5) in a filling and/or sealing and/or post-processing installation.
G05B 19/418 - Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control [DNC], flexible manufacturing systems [FMS], integrated manufacturing systems [IMS] or computer integrated manufacturing [CIM]
G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
7.
METHOD FOR CLEANING AN INSTALLATION, INSTALLATION HAVING A CLEANING SYSTEM, AND USE OF A CLEANING SYSTEM IN AN INSTALLATION
The invention relates to a method for cleaning an installation for producing and/or processing highly active substances, such as for preparing and/or filling pharmaceuticals or biopharmaceuticals, using a hand-guided cleaning apparatus (10), such as a cleaning lance and/or a cleaning brush, wherein, in a cleaning cycle, an actual movement of the cleaning apparatus (10) is detected by a sensor device (12), a deviation of the actual movement from a target movement is determined, and the cleaning cycle is evaluated on the basis of the determined deviation. The invention also relates to an installation (3) having a cleaning system and to the use of a cleaning system for cleaning an installation (3). Finally, the invention relates to a computer program product.
The invention relates to a device (1) for removing containers (2) from a nest (20) or tray (22), wherein the containers (2) are arranged in the nest (20) or tray (22) in a plurality of container rows (201, 202, ..., 212). The device comprises a handling device (4) with a first gripping unit (31) and a second gripping unit (32), wherein the handling device (4) is configured to position the first gripping unit (31) on a first container row of the number of container rows (201, 202, ..., 212) of a nest (20) or tray (22) arranged in a transfer position (60), to grip at least one container (2) from the first container row using the first gripping unit (31), and to move the at least one container (2) gripped using the first gripping unit (31) into a first depositing position (51), and to position the second gripping unit (32) on a second container row of the number of container rows (201, 202, ..., 212) of the nest (21) or tray (22) arranged in the transfer position (60), in order to grip at least one container (2) from the second container row using the second gripping unit (32), and to move the at least one container (2) gripped using the second gripping unit into the first depositing position (51) and/or a second depositing position (52). The invention further relates to a method for removing containers from a nest or tray.
B25J 9/04 - Programme-controlled manipulators characterised by movement of the arms, e.g. cartesian co-ordinate type by rotating at least one arm, excluding the head movement itself, e.g. cylindrical co-ordinate type or polar co-ordinate type
B65B 43/46 - Feeding or positioning bags, boxes, or cartons in the distended, opened, or set-up stateFeeding preformed rigid containers, e.g. tins, capsules, glass tubes, glasses, to the packaging positionLocating containers or receptacles at the filling positionSupporting containers or receptacles during the filling operation using grippers
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
B65B 21/12 - Introducing or removing single bottles, or groups of bottles, e.g. for progressive filling or emptying of containers using grippers engaging bottles, e.g. bottle necks
B65B 21/18 - Introducing or removing groups of bottles, for filling or emptying containers in one operation using grippers engaging bottles, e.g. bottle necks
B65B 69/00 - Unpacking of articles or materials, not otherwise provided for
B65G 47/08 - Devices for feeding articles or materials to conveyors for feeding articles from a single group of articles arranged in orderly pattern, e.g. workpieces in magazines spacing or grouping the articles during feeding
B65B 65/00 - Details peculiar to packaging machines and not otherwise provided forArrangements of such details
B65G 47/91 - Devices for picking-up and depositing articles or materials incorporating pneumatic, e.g. suction, grippers
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
The invention relates to an apparatus and a method for straightening a foil bag (2) with a sterile object (20) packaged therein, wherein the foil bag (2) is pierced by means of a hollow needle (40), gas is injected into the foil bag (2), and a detaching force is applied to the foil bag (2) before piercing into the foil bag (2), with the result that the foil bag (2) is detached from the sterile object (20) packaged therein at least in a region which lies opposite the hollow needle (40).
The invention relates to a method and a device for monitoring a filling and/or closing installation and/or a post-processing installation, in particular for the pharmaceutical industry, wherein an image of a transport, infeed and/or outfeed region (2, 3, 6) of the filling and/or closing and/or post-processing installation is taken using a camera system (10) and, wherein on the basis of the image, by use of an artificial intelligence model (AI model) (120) that is trained to detect primary packaging means in the transport, infeed and/or outfeed region (2, 3, 6) and to classify detected primary packaging means, it is determined in which image positions primary packaging means are present, and detected primary packaging means are assigned to a class. The invention further relates to a filling and/or closing installation and/or post-processing installation and to a computer program for monitoring a filling and/or closing installation and/or post-processing installation.
B65B 57/14 - Automatic control, checking, warning or safety devices responsive to absence, presence, abnormal feed, or misplacement of articles or materials to be packaged and operating to control, or stop, the feed of articles or material to be packaged
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
11.
METHOD AND DEVICE FOR REMEDYING DISTURBANCES IN A FILLING AND/OR SEALING AND/OR POST-PROCESSING INSTALLATION
The invention relates to a method and a device for handling of disturbances in a filling and/or closing and/or post-processing installation for the pharmaceutical industry using a manipulator (14), wherein a path along which the manipulator (14) is moved for collision-free handle of the disturbance is planned in such a way that travel paths of the manipulator (14) which influence a primary air supply (5) of primary packaging means and/or of components of the filling and/or closing and/or post-processing installation which are in contact with the primary packaging means are minimized. The invention further relates to a filling and/or closing and/or post-processing installation and a computer program for a filling and/or closing and/or post-processing installation.
B65B 57/08 - Automatic control, checking, warning or safety devices responsive to absence, presence, abnormal feed, or misplacement of binding or wrapping material, containers, or packages and operating to stop, or to control the speed of, the machine as a whole
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
The invention relates to a device for removing a closing element from a transport section, in particular a supply section, of a filling and/or closing machine, in particular for the pharmaceutical industry, using a manipulator (3), the device comprising an end effector (2), which can be connected to the manipulator (3) releasably without tools or not releasably without tools for a handling for removing the closing element (4), and a needle (20), wherein the end effector (2) has a holder (22) on which the needle (20) is attached and/or which is produced integrally with the needle (20), and/or wherein the end effector has gripper elements so that the needle (20) can be gripped by the end effector, and wherein the closing element (4) can be speared by the needle (20) and the speared closing element (4) can be removed from the transport section. The invention further relates to a method for removal of a closing element from the transport section using a needle (20), and a use of a needle (20) for removal of a closing element from a transport section of a filling and/or closing machine.
The invention relates to a feeding device (1) for feeding small parts, in particular closure elements, comprising a vibrating spiral conveyor (20) having an outlet (200), a feed rail (20), which is arranged downstream of the outlet in the feed direction, and a vibratory drive (201, 211, 221), wherein, by means of the vibratory drive (201, 211, 212), vibrations can be applied to the vibrating spiral conveyor (20) to move the small parts in the direction of the outlet (200) and to the feed rail (21) to move the small parts along the feed rail (21), wherein an intermediate rail (22) is arranged between the outlet (200) of the vibrating spiral conveyor (20) and the feed rail (21), wherein vibrations can be applied to the intermediate rail (22) by means of the vibratory drive (201, 211, 221) to move the small parts along the intermediate rail (22) in the direction of the feed rail (21), wherein a monitoring device (3), associated with the intermediate rail (22), is provided, wherein the monitoring device (3) is designed to detect an abnormality and/or disturbance in the movement of the small parts along the intermediate rail (22), and wherein the feeding device is designed to temporarily interrupt the application of vibrations to the intermediate rail (22) and to the vibrating spiral conveyor (20) to rectify an abnormality and/or disturbance without interrupting the application of vibrations to the feed rail (21) for moving the small parts along the feed rail (21). The invention further relates to a method for feeding small parts.
B65G 27/02 - Jigging conveyors comprising helical or spiral channels or conduits for elevation of materials
B65G 27/34 - Jigging conveyors comprising a series of co-operating units
B65G 47/14 - Devices for feeding articles or materials to conveyors for feeding articles from disorderly-arranged article piles or from loose assemblages of articles arranging or orientating the articles by mechanical or pneumatic means during feeding
B07C 5/00 - Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or featureSorting by manually actuated devices, e.g. switches
The invention relates to a method and a device (2) for filling multiple containers (1) in a nest (10) comprising columns (101) and rows (102), in particular for filling nesting ampoules or carpules, wherein multiple, in particular all, containers arranged in a column are filled simultaneously by means of a filling needle (200), wherein, during the filling processes of the containers (1), a reaching of a defined fill level is detected by means of a sensor device (21), and wherein the detected reaching of the defined fill level triggers a stop signal for the filling process of the respective container (1).
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 3/26 - Methods or devices for controlling the quantity of the material fed or filled
B65B 43/59 - Means for supporting containers or receptacles during the filling operation vertically movable
B65B 57/14 - Automatic control, checking, warning or safety devices responsive to absence, presence, abnormal feed, or misplacement of articles or materials to be packaged and operating to control, or stop, the feed of articles or material to be packaged
B67C 3/22 - Bottling liquids or semiliquidsFilling jars or cans with liquids or semiliquids using bottling or like apparatus Details
B67C 3/26 - Filling-headsMeans for engaging filling-heads with bottle necks
B67C 3/28 - Flow-control devices, e.g. using valves
B67C 7/00 - Concurrent cleaning, filling, and closing of bottlesProcesses or devices for at least two of these operations
The invention relates to an apparatus and a method for straightening a foil bag (2) with a sterile object (20) packaged therein, wherein the foil bag (2) is pierced by means of a hollow needle (40), gas is injected into the foil bag (2), and a detaching force is applied to the foil bag (2) before piercing into the foil bag (2), with the result that the foil bag (2) is detached from the sterile object (20) packaged therein at least in a region which lies opposite the hollow needle (40).
The invention relates to a method and a device for monitoring a filling and/or closing installation and/or a post-processing installation, in particular for the pharmaceutical industry, wherein an image of a transport, infeed and/or outfeed region (2, 3, 6) of the filling and/or closing and/or post-processing installation is taken using a camera system (10) and, wherein on the basis of the image, by use of an artificial intelligence model (Al model) (120) that is trained to detect primary packaging means in the transport, infeed and/or outfeed region (2, 3, 6) and to classify detected primary packaging means, it is determined in which image positions primary packaging means are present, and detected primary packaging means are assigned to a class. The invention further relates to a filling and/or closing installation and/or post-processing installation and to a computer program for monitoring a filling and/or closing installation and/or post-processing installation.
The invention relates to a method and a device for handling of disturbances in a filling and/or closing and/or post-processing installation for the pharmaceutical industry using a manipulator (14), wherein a path along which the manipulator (14) is moved for collision-free handle of the disturbance is planned in such a way that travel paths of the manipulator (14) which influence a primary air supply (5) of primary packaging means and/or of components of the filling and/or closing and/or post-processing installation which are in contact with the primary packaging means are minimized. The invention further relates to a filling and/or closing and/or post-processing installation and a computer program for a filling and/or closing and/or post-processing installation.
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 7/28 - Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
B65B 57/08 - Automatic control, checking, warning or safety devices responsive to absence, presence, abnormal feed, or misplacement of binding or wrapping material, containers, or packages and operating to stop, or to control the speed of, the machine as a whole
The invention relates to a device and a method for freeze-drying products, wherein products are arranged in a drying chamber (2) for a freeze-drying process, wherein energy is supplied to the products arranged in the drying chamber (2) by means of microwaves at least during some parts of the freeze-drying process, and wherein the microwaves are generated by at least one microwave module (6) based on semiconductor technology. The invention also relates to the use of a microwave module (6) based on semiconductor technology in a freeze-drying process.
F26B 3/347 - Electromagnetic heating, e.g. induction heating or heating using microwave energy
F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
The invention relates to a device and a method for freeze-drying products, wherein products for a freeze-drying process are arranged in a drying chamber (2), wherein, during the freeze-drying process, energy is fed at least intermittently to the products arranged in the drying chamber (2) by means of microwaves, and wherein the microwaves are generated by means of at least one microwave module (6) based on semiconductor technology. The invention furthermore relates to the use of a microwave module (6) based on semiconductor technology in a freeze-drying process.
F26B 3/347 - Electromagnetic heating, e.g. induction heating or heating using microwave energy
F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
The invention relates to a method for freeze-drying products in a product chamber (2), said product chamber (2) being connected to a condenser (3) via a valve (4), having the following steps: ∙ a) lowering the pressure in the product chamber (2) and the condenser (3) at a temperature lying below the freezing point of the product until a defined pressure is reached which lies below the atmospheric pressure and above a product-specific nucleation pressure at which nucleation sets in; ∙ b) closing the valve (4) between the product chamber (2) and the condenser (3); ∙ c) maintaining the pressure in the product chamber (2) and further lowering the pressure in the condenser (3); ∙ d) opening the valve (4) between the product chamber (2) and the condenser (3) after or upon reaching the product-specific nucleation pressure in the condenser (3) such that the pressure in the product chamber (2) is lowered to a pressure below the product-specific nucleation pressure. The invention additionally relates to a device for carrying out the method.
F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
A conveying device for conveyed goods, comprising a conveying rake having at least one prong, and a first drive assembly which is operatively connected to the conveying rake. The conveying rake is drivable by the first drive assembly so as to perform a reciprocating movement in the conveying direction and to perform a reciprocating movement in a penetration direction. The conveying device furthermore has a mating rake having at least one prong, and a second drive assembly which is operatively connected to the mating rake. The mating rake is displaceable in the conveying direction in relation to the conveying rake, so as to clamp conveyed goods between the prong of the conveying rake and the assigned prong of the mating rake. A method for operating a conveying device for conveyed goods is also disclosed.
B65G 47/82 - Rotary or reciprocating members for direct action on articles or materials, e.g. pushers, rakes, shovels
B65G 25/02 - Conveyors comprising a cyclically-moving, e.g. reciprocating, carrier or impeller which is disengaged from the load during the return part of its movement the carrier or impeller having different forward and return paths of movement, e.g. walking-beam conveyors
B65G 25/04 - Conveyors comprising a cyclically-moving, e.g. reciprocating, carrier or impeller which is disengaged from the load during the return part of its movement the carrier or impeller having identical forward and return paths of movement, e.g. reciprocating conveyors
B65G 15/14 - Conveyors having endless load-conveying surfaces, i.e. belts and like continuous members, to which tractive effort is transmitted by means other than endless driving elements of similar configuration comprising two or more co-operating endless surfaces with parallel longitudinal axes, or a multiplicity of parallel elements, e.g. ropes defining an endless surface with two or more endless belts the load being conveyed between the belts
The invention relates to a treatment device, comprising at least one excitation apparatus (3, 103, 503) for producing pressure waves, wherein the treatment device (1, 101, 201, 401) comprises a closed treatment chamber (40, 240) for a vacuum process and/or a positive-pressure process, the at least one excitation apparatus (3, 103, 503) can be operated in order to produce, simultaneously or in cycles, at least two pressure waves that interfere in-phase at a focus (20) in order to produce a compression wave and/or an expansion wave for the vacuum process and/or the positive-pressure process at least one time at the focus (20), and the treatment chamber (40, 240) is arranged at the focus (20). The invention further relates to a system comprising at least two treatment devices and a method for producing a vacuum and/or a positive pressure in a treatment chamber.
B01J 19/10 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing sonic or ultrasonic vibrations