Abstract

The present specification provides an antisense oligomer, or a pharmaceutically acceptable salt thereof, or a hydrate of the antisense oligomer or the salt having a length of 15 to 30 bases, comprising a base sequence complementary to a base sequence in a target region, wherein the target region comprises a sequence of at least 10 consecutive bases in at least one region selected from the group consisting of a 5′ UTR region, a nsp1 region, a nsp10 region, an RNA-dependent RNA polymerase region, an ORF10 region, and a 3′ UTR region in the genome RNA of SARS-CoV-2, or a complementary sequence thereof, wherein the antisense oligomer, or the pharmaceutically acceptable salt thereof, or the hydrate of the antisense oligomer or the salt has an antiviral effect on a virus selected from the group consisting of SARS-CoV-2, SARS-CoV-1, and MERS-CoV.

IPC Classes  ?

• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A61P 31/14 - Antivirals for RNA viruses

Abstract

The present specification provides an antisense oligonucleotide or a pharmaceutically acceptable salt or hydrate thereof targeting a particular region in genomic RNA of SARS-CoV-2, a pharmaceutical composition comprising the antisense oligonucleotide or the pharmaceutically acceptable salt or hydrate thereof, etc.

IPC Classes  ?

• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

Abstract

A biodegradable resin composition is usable for producing a molded article having high biodegradability particularly in the ocean. The biodegradable resin composition contains a biodegradable resin and one or more components selected from agarose, sodium alginate, casein, and keratin. The content of the biodegradable resin is 50% by weight or more.

IPC Classes  ?

• C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones
• C08L 67/02 - Polyesters derived from dicarboxylic acids and dihydroxy compounds

Abstract

An object of the present invention is to provide an antiviral nucleic acid, etc. against SARS-COV-2 SARS-COV-2, SARS-COV-1, or MERS-COV and/or a method for treating and/or preventing viral infection using the nucleic acid, etc. The present invention relates to, for example, an antiviral nucleic acid or a pharmaceutically acceptable salt or hydrate thereof targeting a sequence in at least one target region selected from the group consisting of 5′ UTR region, nsp3 region, 3C-like proteinase region, nsp9 region, RNA-dependent RNA polymerase region, helicase region, 3′-to-5′ exonuclease region, 2′-O-ribose methyltransferase region, S region including S1 region and S2 region, E region, M region, and N region in genomic RNA of SARS-COV-2, wherein the virus is SARS-COV-2, SARS-COV-1, or MERS-COV.

IPC Classes  ?

• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A61K 31/712 - Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
• A61K 31/7125 - Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
• A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
• A61P 31/12 - Antivirals

Abstract

A promoter on an AAV vector was changed to an Iba1 promoter, and a configuration that combined a miR-9 complementary sequence (miR-9T) and a miR-129 complementary sequence (miR-129T) was adopted. An exogenous gene was clarified to be efficiently and specifically expressed in microglia by using this vector, resulting in that an AAV vector that could efficiently and specifically express an exogenous gene in microglia of the central nervous system, was found.

IPC Classes  ?

• C12N 15/86 - Viral vectors
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy

Abstract

Provided is a motor control device capable of improving efficiency in real time by a neural network structure that directly derives, in a learning manner, an output signal providing optimal efficiency. A motor control device 1 is adapted to control a motor 6, and includes a neural network compensator 11 that receives input signals and repeats learning based on forward propagation and backpropagation thereby to derive an output signal providing optimal efficiency. Input signals are a motor current, a motor parameter and torque, and the like, and output signals are a current command value and a current phase command value. The motor 6 is controlled on the basis of an output signal derived by the neural network compensator 11.

IPC Classes  ?

• H02P 21/00 - Arrangements or methods for the control of electric machines by vector control, e.g. by control of field orientation
• H02P 21/13 - Observer control, e.g. using Luenberger observers or Kalman filters
• H02P 21/18 - Estimation of position or speed
• H02P 21/22 - Current control, e.g. using a current control loop
• G06N 3/084 - Backpropagation, e.g. using gradient descent

Abstract

Fucosylated α1-acid glycoprotein (fAGP) was found to be useful for the diagnosis of pancreatic cancer and malignant intraductal papillary mucinous neoplasm (IPMC), resulting in the finding of a new biomarker for pancreatic cancer or malignant intraductal papillary mucinous neoplasm (IPMC), in particular, a new biomarker useful for rapid diagnosis of malignant intraductal papillary mucinous neoplasm (IPMC) that increases the accuracy of malignant intraductal papillary mucinous neoplasm (IPMC) and aids conventional imaging diagnosis by making a suitable preoperative diagnosis of a benign neoplasm or a malignant neoplasm in intraductal papillary mucinous neoplasm (IPMN).

IPC Classes  ?

• G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals

Abstract

A blood measurement device (10) includes a light emitting part (11) that emits a light beam that is to transmit through a measurement site (18), a light receiving part (19) that receives the light beam that has transmitted through the measurement site (18), an integrating sphere part (14) interposed in an optical path along which the light beam emitted from the light emitting part (11) reaches the light receiving part (19), the integrating sphere part (14) having formed inside a reflection surface (26) that reflects the light beam, a light entry part (23) which is an opening provided at the integrating sphere part (14) and through which the light beam applied from the light emitting part (11) enters an inside of the integrating sphere part (14), and a light exit part (16) which is an opening provided at the integrating sphere part (14) and through which the light beam reflected by the reflection surface (26) of the integrating sphere part (14) is emitted from the integrating sphere part (14) toward the measurement site (18).

IPC Classes  ?

• A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
• A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value

Abstract

It is an object of the present invention to provide a therapeutic drug for carcinomatous peritonitis. According to the present invention, a therapeutic drug for carcinomatous peritonitis which comprises an antibody which recognizes a transferrin receptor, is provided.

IPC Classes  ?

• C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
• A61P 35/00 - Antineoplastic agents
• A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
• A61P 1/18 - Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes

Abstract

Provided is a blood measurement device capable of accurately estimating the amount of a component contained in blood by passing light beams for calculating the amount of the component contained in blood along the same optical axis. A blood measurement device 10 of the present invention includes a light emitting part 11 having a first light emitting part 111 and a second light emitting part 112, a light receiving part 19, an actuator 16, and a computation and control part 17 that estimates a glucose level and controls operation of the actuator 16. When applicating a first light beam from the first light emitting part 111 to a measurement site, the computation and control part 17 causes the actuator 16 to move a light emission point of the first light emitting part 111 onto an optical axis 22 defined to penetrate through the measurement site, and when applicating a second light beam from the second light emitting part 112 to the measurement site, the computation and control part 17 causes the actuator 16 to move a light emission point of the second light emitting part 112 onto the optical axis 22.

IPC Classes  ?

• A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
• A61B 5/00 - Measuring for diagnostic purposes Identification of persons

Abstract

An electrode for a redox flow battery, including a plate-shaped carbon electrode material, in which uniform consecutive macropores are formed in a three-dimensional network form and contact interface between carbon particles does not exist, in which: an average macropore diameter of the carbon electrode material is in a range of from 6 μm to 35 μm; an interplanar distance of (002) planes of a graphite crystallite in the carbon electrode material is in a range of from 0.33 nm to 0.40 nm; and a crystallite size of a graphite crystallite in a c-axis direction in the carbon electrode material is in a range of from 0.9 nm to 8.5 nm.

IPC Classes  ?

• H01M 4/583 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx
• H01M 8/18 - Regenerative fuel cells, e.g. redox flow batteries or secondary fuel cells
• H01M 4/04 - Processes of manufacture in general
• H01M 4/36 - Selection of substances as active materials, active masses, active liquids

Abstract

An imaging device includes a varifocal lens and an imaging sensor which outputs a signal corresponding to light. The imaging sensor includes a photoelectric conversion unit which converts light into an electric charge, electric charge reading regions, transfer control electrodes, a gate control circuit which sequentially applies control signals to the transfer control electrodes to correspond to the position of the focal point of the varifocal lens, and a reading circuit which outputs a signal corresponding to the amount of the electric charge transferred to the electric charge reading regions. The gate control circuit repeats an operation of outputting each of the control signals when the position of the focal point is located in the focal ranges during a frame period.

IPC Classes  ?

• H04N 25/50 - Control of the SSIS exposure
• H04N 25/77 - Pixel circuitry, e.g. memories, A/D converters, pixel amplifiers, shared circuits or shared components
• G02B 7/28 - Systems for automatic generation of focusing signals
• H04N 13/236 - Image signal generators using stereoscopic image cameras using a single 2D image sensor using varifocal lenses or mirrors

Abstract

A volumetric display capable of high-speed image presentation includes a resonance-type liquid lens having a focal length that is periodically adjusted using resonance of a liquid. An image projector projects an image toward a viewpoint position of a user via the resonance-type liquid lens. Further, the image projector projects an image toward the viewpoint position within a shorter time period than one-tenth of a variation cycle of the focal length. The image projector includes an LED and a DMD, for example.

IPC Classes  ?

• G02B 30/50 - Optical systems or apparatus for producing three-dimensional [3D] effects, e.g. stereoscopic images the image being built up from image elements distributed over a 3D volume, e.g. voxels
• H04N 13/388 - Volumetric displays, i.e. systems where the image is built up from picture elements distributed through a volume
• H04N 13/365 - Image reproducers using digital micromirror devices [DMD]
• H04N 13/398 - Synchronisation thereofControl thereof
• G02F 1/29 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the position or the direction of light beams, i.e. deflection
• G02F 1/33 - Acousto-optical deflection devices
• G03B 21/00 - Projectors or projection-type viewersAccessories therefor
• G03B 21/20 - Lamp housings

Abstract

The present invention aims to develop a compound and a reagent having long phosphorescence lifetimes, for use in imaging of a hypoxic cell/tissue or for use in measurement/quantification of the oxygen concentration thereof. The present invention provides a reagent for measuring oxygen concentration, comprising a compound represented by the following General Formula (I) or (II). The present invention aims to develop a compound and a reagent having long phosphorescence lifetimes, for use in imaging of a hypoxic cell/tissue or for use in measurement/quantification of the oxygen concentration thereof. The present invention provides a reagent for measuring oxygen concentration, comprising a compound represented by the following General Formula (I) or (II). The present invention aims to develop a compound and a reagent having long phosphorescence lifetimes, for use in imaging of a hypoxic cell/tissue or for use in measurement/quantification of the oxygen concentration thereof. The present invention provides a reagent for measuring oxygen concentration, comprising a compound represented by the following General Formula (I) or (II). wherein R1 and R2 each independently represent hydrogen or a C1-C6 hydrocarbon group; and X− represents a counter anion.

IPC Classes  ?

• C07F 15/00 - Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
• A61K 49/00 - Preparations for testing in vivo
• G01N 21/64 - FluorescencePhosphorescence

Abstract

B>1), thereby forming a more moderate electric field region. A reduced gold fine particle group (average particle size: 20 nm) was self-assembled on a transparent polyester resin film and half-submerged and fixed. This base material was repeatedly immersed in an electroless gold plating solution so that gold particles were deposited on the gold fine particles. 10 microliters of a protein solution was added dropwise to this nanostructured substrate, and crystallized by a hanging drop vapor diffusion method.

IPC Classes  ?

• C30B 29/58 - Macromolecular compounds
• B01J 19/12 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing electromagnetic waves
• C07K 1/30 - ExtractionSeparationPurification by precipitation
• C30B 7/00 - Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
• C30B 30/04 - Production of single crystals or homogeneous polycrystalline material with defined structure characterised by the action of electric or magnetic fields, wave energy or other specific physical conditions using magnetic fields
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites

Abstract

The present invention aims to provide a fluorescent reagent capable of highly sensitive imaging of a lipid droplet at a level ranging from cultured cells to individuals. A lipid droplet detection reagent including a compound represented by the following General Formula (I) is provided. 3; and y represents an integer of 0 to 5.

IPC Classes  ?

• C07D 519/00 - Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or
• G01N 21/64 - FluorescencePhosphorescence
• G01N 33/92 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving lipids, e.g. cholesterol

Abstract

1 is an aliphatic hydrocarbon group having 10 to 26 carbon atoms.

IPC Classes  ?

• C07H 15/04 - Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of a saccharide radical
• C07H 7/02 - Acyclic radicals

Abstract

There is provided with a porphyrin compound represented by Formula (I) or a salt thereof; 6 alkyl group, and Rx is a substituent represented by General Formula. The porphyrin compound is useful as a cancer therapeutic agent, photosensitizer and fluorescent probe.

IPC Classes  ?

• C07H 17/02 - Heterocyclic radicals containing only nitrogen as ring hetero atoms
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation

Abstract

A method for detecting a gene mutation(s), the method comprising the steps of: hybridizing a single-stranded circular DNA and a primer with a target polynucleotide containing a first region and a second region adjacent to the 3′-side of the first region and containing a mutation; performing a nucleic acid amplification reaction by rolling circle amplification based on formation of a complex of the target polynucleotide, the primer, and the single-stranded circular DNA; and detecting amplified nucleic acid with a detection reagent. In this method, the single-stranded circular DNA contains a sequence complementary to the first region of the target polynucleotide, a primer-binding sequence adjacent to the 5′-side thereof, and preferably a sequence complementary to a detection reagent-binding sequence. The oligonucleotide primer contains a region having a sequence complementary to the second region of the target polynucleotide, and a region adjacent to the 3′-side thereof and having a sequence complementary to the primer-binding sequence of the single-stranded circular DNA.

IPC Classes  ?

• C12Q 1/6827 - Hybridisation assays for detection of mutation or polymorphism

Abstract

Methods are provided for predicting a response to an anti-PD-1 antibody or anti-PD-L1 antibody therapy based on a new biomarker and for evaluating a malignancy of cancer. The method for predicting a response of a subject to an anti-PD-1 antibody or anti-PD-L1 antibody therapy includes measuring an expression level of LAT1 in a sample collected from a cancer tissue of the subject; and predicting a response of the subject to the anti-PD-1 antibody or anti-PD-L1 antibody therapy based on the expression level of LAT1. The method for evaluating a malignancy of cancer in a subject includes staining a sample collected from a cancer tissue of the subject with an anti-LAT1 antibody and an anti-PD-L1 antibody; and evaluating a malignancy of the cancer in the subject based on a presence or absence of a LAT1-positive and PD-L1-positive site.

IPC Classes  ?

• C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
• A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
• A61K 31/423 - Oxazoles condensed with carbocyclic rings
• A61P 35/00 - Antineoplastic agents
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

Provided is a substance capable of effectively suppressing cancer metastasis or a pharmaceutical composition that effectively acts on an inflammatory disease. The pharmaceutical composition is a pharmaceutical composition containing, as an active ingredient, an antibody or an antibody fragment thereof having antigen-binding activity for an S100A8/A9 heterodimer, and blocks interaction between S100A8/A9 and a group of receptors therefor, to thereby strongly suppress cancer metastasis both in vitro and in vivo, or alleviate inflammation. That is, the anti-S100A8/A9 antibody or the antibody fragment thereof can strongly suppress cancer metastasis or alleviate inflammation, by virtue of its blocking action on the interaction between S100A8/A9 and the group of receptors therefor.

IPC Classes  ?

• C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies
• C07K 16/46 - Hybrid immunoglobulins
• C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
• A61P 11/00 - Drugs for disorders of the respiratory system
• A61P 35/04 - Antineoplastic agents specific for metastasis
• A61K 39/00 - Medicinal preparations containing antigens or antibodies

Abstract

A sound insulating member includes a mass section and spring sections. The mass section is disposed so as to have a gap with respect to an outer panel which divides an internal space of a vehicle body and outside thereof, and includes at least a part which has a planar shaped form. The plurality of spring sections are disposed on the mass section at a side of the mass section facing an outer panel. Each of the spring sections has a hollow film member having airtightness and flexibility, and a gas sealed inside the film member. The film member has a first stepped section and a second stepped section that are formed in a stepped shape in an arrangement direction of the outer panel and the mass section.

IPC Classes  ?

• B60R 13/07 - Water drainage or guide means not integral with roof structure
• B60R 13/08 - Insulating elements, e.g. for sound insulation
• B60R 13/02 - Trim mouldingsLedgesWall linersRoof liners
• B62D 25/00 - Superstructure sub-unitsParts or details thereof not otherwise provided for

Abstract

A DNA methylation editing kit comprises: (1) a fusion protein of inactivated CRISPR-associated endonuclease Cas9 (dCas9) having no nuclease activity and a tag peptide array in which plural tag peptides are linked by linkers, or an RNA or DNA coding therefor; (2) a fusion protein(s) of a tag peptide-binding portion and a methylase or demethylase, or an RNA(s) or DNA(s) coding therefor; and (3) a guide RNA(s) (gRNA(s)) comprising a sequence complementary to a DNA sequence within 1 kb of a desired site of methylation or demethylation, or a DNA(s) expressing the gRNA(s).

IPC Classes  ?

• C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
• C12N 15/90 - Stable introduction of foreign DNA into chromosome
• C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans
• C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
• C12N 9/10 - Transferases (2.)
• C12N 15/09 - Recombinant DNA-technology
• C07K 16/44 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere
• C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof

Abstract

A method of detecting a target molecule, the method comprising: forming a complex of a target molecule, a capture oligonucleotide, an oligonucleotide primer, and a single-stranded circular DNA; performing a nucleic acid amplification reaction by rolling circle amplification based on the formation of the complex; and detecting amplified nucleic acid; wherein the single-stranded circular DNA contains a first region, and a second region linked to the 3′-side of the first region, and preferably further contains a sequence complementary to a detection reagent-binding sequence; the primer contains a first aptamer sequence which binds to the target molecule, and a sequence which is linked to the 3′-side of the first aptamer sequence and is complementary to the first region of the single-stranded circular DNA; and the capture oligonucleotide contains a sequence complementary to the second region of the single-stranded circular DNA, and a second aptamer sequence which is linked to the 3′-side of the sequence complementary to the second region and binds to the target molecule.

IPC Classes  ?

• C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
• C12N 15/115 - Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith
• C12Q 1/6844 - Nucleic acid amplification reactions
• C07D 277/66 - Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2

Abstract

narrow: 0.4% or more and 15% or less.

IPC Classes  ?

• C01B 31/08 - Active carbon
• H01M 4/90 - Selection of catalytic material
• H01M 12/06 - Hybrid cellsManufacture thereof composed of a half-cell of the fuel-cell type and of a half-cell of the primary-cell type with one metallic and one gaseous electrode
• H01M 8/10 - Fuel cells with solid electrolytes
• B01J 21/18 - Carbon
• H01M 12/08 - Hybrid cellsManufacture thereof composed of a half-cell of a fuel-cell type and a half-cell of the secondary-cell type
• B01J 37/08 - Heat treatment
• H01M 4/587 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx for inserting or intercalating light metals
• H01M 4/583 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx
• H01M 4/133 - Electrodes based on carbonaceous material, e.g. graphite-intercalation compounds or CFx
• C01B 32/05 - Preparation or purification of carbon not covered by groups , , ,
• C01B 32/306 - Active carbon with molecular sieve properties
• H01M 8/1004 - Fuel cells with solid electrolytes characterised by membrane-electrode assemblies [MEA]
• H01M 8/1018 - Polymeric electrolyte materials

Abstract

2 to a culture vessel, and culturing the cells for 14 to 42 days.

IPC Classes  ?

• C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
• C12N 5/0797 - Stem cellsProgenitor cells
• C12N 5/074 - Adult stem cells
• C12N 5/0735 - Embryonic stem cellsEmbryonic germ cells
• C12N 5/0793 - Neurons
• C12N 5/079 - Neural cells

Abstract

The present invention provides a novel nucleoside derivative or a salt thereof, a polynucleotide synthesis reagent, a method for producing a polynucleotide, a polynucleotide, and a method for producing a binding nucleic acid molecule. The nucleoside derivative or a salt thereof of the present invention is represented by the following chemical formula (1). 1 is a hydrogen atom or a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms.

IPC Classes  ?

• C07H 19/10 - Pyrimidine radicals with the saccharide radical being esterified by phosphoric or polyphosphoric acids
• C07H 19/20 - Purine radicals with the saccharide radical being esterified by phosphoric or polyphosphoric acids
• C12N 15/115 - Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• C07H 1/00 - Processes for the preparation of sugar derivatives
• C07H 21/00 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
• C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
• C07H 21/02 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical

Abstract

A method of producing a conditional knockout animal, and techniques related thereto, e.g., a method of efficiently producing a floxed animal, are provided. By introducing recombinase recognition sequences such as loxP into both ends of a target region on a chromosome at different timings, an animal having the pair of recombinase recognition sequences on the chromosome, such as a floxed animal, is produced.

IPC Classes  ?

• A01K 67/027 - New or modified breeds of vertebrates
• C12N 15/873 - Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos

Abstract

The purpose of the present invention is to provide an injectable sol into a body, suited for delivery through a catheter, and usable for tissue perforation closure, ulcer protection, or vascular embolization. Provided are a sol for tissue perforation closure, a sol for ulcer protection, and a sol for vascular embolization, each containing from 0.6 mass % to 3 mass % of a collagen, water, from 200 mM to 330 mM sodium chloride, and a buffer and having a pH from 6.0 to 9.0.

IPC Classes  ?

• A61L 24/10 - PolypeptidesProteins
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 47/02 - Inorganic compounds
• A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
• A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
• A61L 31/14 - Materials characterised by their function or physical properties
• A61K 9/06 - OintmentsBases therefor
• A61L 27/24 - Collagen
• A61L 31/04 - Macromolecular materials

Abstract

Object of the present invention is to provide a safe sol for submucosal local injection which gels and creates a mucosal elevation having a high retention rate of mucosal elevation height when locally injected into a digestive submucosa. Provided is a sol for submucosal local injection containing from 0.2 mass % to 1.2 mass % of a collagen, water, a buffer, and from 200 mM to 420 mM sodium chloride.

IPC Classes  ?

• A61L 31/04 - Macromolecular materials
• A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
• A61L 31/16 - Biologically active materials, e.g. therapeutic substances
• A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
• A61K 9/06 - OintmentsBases therefor
• A61B 17/32 - Surgical cutting instruments
• A61L 31/14 - Materials characterised by their function or physical properties
• A61L 33/12 - Polypeptides, proteins or derivatives thereof
• A61B 17/28 - Surgical forceps
• A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
• A61K 47/02 - Inorganic compounds

Abstract

A carbon catalyst has improved catalytic activity, and an electrode and a battery include the carbon catalyst. A carbon catalyst includes a metal and phosphorus atoms, wherein a ratio of a concentration (atomic %) of the phosphorus atoms exhibiting a peak having a peak top within a range of 132.5±0.3 eV and having a full width at half maximum of 2.0±0.5 eV, which is obtained by peak separation of a phosphorus atom P2p peak, with respect to a concentration (atomic %) of carbon atoms in X-ray photoelectron spectroscopic measurement is 0.0005 or more.

IPC Classes  ?

• H01M 4/90 - Selection of catalytic material
• B01J 21/18 - Carbon
• B01J 27/185 - PhosphorusCompounds thereof with iron group metals or platinum group metals
• B01J 31/02 - Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides

Abstract

The present invention provides a novel nucleoside derivative or a salt thereof, a polynucleotide synthesis reagent, a method for producing a polynucleotide, a polynucleotide, and a method for producing a binding nucleic acid molecule. The nucleoside derivative or a salt thereof of the present invention is represented by the following chemical formula (1): 1 is a hydrogen atom or a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms.

IPC Classes  ?

• C07H 19/10 - Pyrimidine radicals with the saccharide radical being esterified by phosphoric or polyphosphoric acids
• C07H 19/067 - Pyrimidine radicals with ribosyl as the saccharide radical
• C07H 19/073 - Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
• C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies
• C12N 15/115 - Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith
• C07H 21/00 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Abstract

The present invention provides a novel molecule that can be used for detection of sIgA. The sIgA-binding nucleic acid molecule of the present invention is characterized in that it binds to secretory immunoglobulin A (sIgA) with a dissociation constant of 37.7 nM or less, and preferably includes a polynucleotide consisting of any of base sequences of SEQ ID NOs: 1 to 12 or a partial sequence thereof, for example. According to the sIgA-binding nucleic acid molecule of the present invention, it is possible to detect sIgA in saliva.

IPC Classes  ?

• C12N 15/115 - Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith
• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
• C12N 15/09 - Recombinant DNA-technology

Abstract

The present invention provides a novel nucleoside derivative or a salt thereof, a polynucleotide synthesis reagent, a method for producing a polynucleotide, a polynucleotide, and a method for producing a binding nucleic acid molecule. The nucleoside derivative or a salt thereof of the present invention is represented by the following chemical formula (1): 1 is a hydrogen atom or a straight-chain or branched, saturated or unsaturated hydrocarbon group having 2 to 10 carbon atoms.

IPC Classes  ?

• C07H 19/02 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radicalNucleosidesMononucleotidesAnhydro derivatives thereof sharing nitrogen
• C07H 19/04 - Heterocyclic radicals containing only nitrogen as ring hetero atom
• C07H 19/14 - Pyrrolo-pyrimidine radicals
• C07H 19/20 - Purine radicals with the saccharide radical being esterified by phosphoric or polyphosphoric acids
• C07H 21/02 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
• C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
• C12N 15/115 - Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith
• C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies

Abstract

broad, is 0.374 nm or more.

IPC Classes  ?

• H01M 4/96 - Carbon-based electrodes
• C01B 32/05 - Preparation or purification of carbon not covered by groups , , ,
• B01J 23/80 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with zinc, cadmium or mercury
• H01M 4/90 - Selection of catalytic material
• H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
• H01M 8/10 - Fuel cells with solid electrolytes

Abstract

A simple production process is provided of a perfluoroalkyl compound that uses monohydroperfluoroalkane as a starting material, the perfluoroalkyl compound being an important intermediate of organic electronic materials, medicine, agricultural chemicals, functional polymer materials and the like. With monohydroperfluoroalkane is reacted a base and then a carbonyl compound to produce an alcohol having a perfluoroalkyl group. For example, potassium hydroxide is made to interact with trifluoromethane, and a reaction with a carbonyl compound is induced to produce an alcohol having a trifluoromethyl group.

IPC Classes  ?

• C07C 29/38 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy groups, e.g. O-metal by reaction with aldehydes or ketones
• C07C 31/125 - Monohydroxylic acyclic alcohols containing five to twenty-two carbon atoms
• C07C 33/46 - Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic part
• C07C 35/48 - Halogenated derivatives
• C07C 43/23 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
• C07C 209/68 - Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
• C07C 211/48 - N-alkylated amines
• C07C 231/12 - Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
• C07C 233/15 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
• C07C 41/30 - Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
• C07C 209/78 - Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton from carbonyl compounds, e.g. from formaldehyde, and amines having amino groups bound to carbon atoms of six-membered aromatic rings, with formation of methylene-diarylamines

Abstract

An RNA detection kit comprising: (i) a single-stranded circular DNA template containing: a sequence of 10 to 30 bases complementary to a first portion of a target RNA; a primer-binding sequence of 7 to 8 bases adjacent to 5′-side thereof; and a sequence complementary to a detection reagent-binding sequence such as a guanine quadruplex-forming sequence; (ii) an oligonucleotide primer containing: a sequence of 8 to 15 bases complementary to a second portion adjacent to the 3′-side of the first portion of the target RNA; and a sequence of 7 to 8 bases adjacent to 3′-side thereof and complementary to the primer-binding sequence of the single-stranded circular DNA template; and (iii) a detection reagent such as a guanine quadruplex-binding reagent; is provided.

IPC Classes  ?

• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
• C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
• C12Q 1/6844 - Nucleic acid amplification reactions

Abstract

A DNA methylation editing kit comprises: (1) a fusion protein of inactivated CRISPR-associated endonuclease Cas9 (dCas9) having no nuclease activity and a tag peptide array in which plural tag peptides are linked by linkers, or an RNA or DNA coding therefor; (2) a fusion protein(s) of a tag peptide-binding portion and a methylase or demethylase, or an RNA(s) or DNA(s) coding therefor; and (3) a guide RNA(s) (gRNA(s)) comprising a sequence complementary to a DNA sequence within 1 kb of a desired site of methylation or demethylation, or a DNA(s) expressing the gRNA(s).

IPC Classes  ?

• C12N 9/00 - Enzymes, e.g. ligases (6.)ProenzymesCompositions thereofProcesses for preparing, activating, inhibiting, separating, or purifying enzymes
• C12N 15/90 - Stable introduction of foreign DNA into chromosome
• C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans
• C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
• C12N 9/10 - Transferases (2.)
• C12N 15/09 - Recombinant DNA-technology
• C07K 16/44 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere
• C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof

Abstract

An effective amount of botulinum toxin type B is administered to a subject in need thereof for treating Raynaud's phenomenon. Botulinum toxin type B may be in a form of an injection, and may be locally administered to a disease affected site, in a dose of 200 to 400 units per disease affected site.

IPC Classes  ?

• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61P 9/00 - Drugs for disorders of the cardiovascular system

Abstract

2 or more at a hydrogen pressure of 10 MPa.

IPC Classes  ?

• C01B 3/00 - HydrogenGaseous mixtures containing hydrogenSeparation of hydrogen from mixtures containing itPurification of hydrogen
• B01J 20/20 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising free carbonSolid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising carbon obtained by carbonising processes
• B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
• B01J 20/30 - Processes for preparing, regenerating or reactivating
• C01B 32/05 - Preparation or purification of carbon not covered by groups , , ,
• C01B 32/318 - Preparation characterised by the starting materials

Abstract

To provide a method for joining metal members, in which joining can be performed at relatively lower temperature, and deformation caused when joining the metal members can be reduced. The present invention includes a step of joining a plurality of metal members with a sheet sandwiched between the joining surfaces of the plurality of metal members, wherein the sheet is obtained by forming an organic acid metal salt film on the surface of a metal sheet; wherein aluminum or an aluminum alloy is used as the metal members, and a sheet made of any one of zinc, copper and magnesium is used as the metal sheet.

IPC Classes  ?

• B23K 31/02 - Processes relevant to this subclass, specially adapted for particular articles or purposes, but not covered by any single one of main groups relating to soldering or welding
• B23K 20/16 - Non-electric welding by applying impact or other pressure, with or without the application of heat, e.g. cladding or plating with interposition of special material to facilitate connection of the parts, e.g. material for absorbing or producing gas
• B23K 1/20 - Preliminary treatment of work or areas to be soldered, e.g. in respect of a galvanic coating
• B23K 20/02 - Non-electric welding by applying impact or other pressure, with or without the application of heat, e.g. cladding or plating by means of a press
• B23K 20/233 - Non-electric welding by applying impact or other pressure, with or without the application of heat, e.g. cladding or plating taking account of the properties of the materials to be welded without ferrous layer
• B23K 20/24 - Preliminary treatment
• B23K 103/10 - Aluminium or alloys thereof
• B23K 103/20 - Ferrous alloys and aluminium or alloys thereof
• B23K 103/12 - Copper or alloys thereof

Abstract

[Problem] To provide highly heat-resistant and radiation-resistant radiation measuring equipment. [Solution] Provided are a charged particle radiation measuring method and a charged particle radiation measuring device using a scintillator comprising a phosphor in which the main component is a SiAlON phosphor.

IPC Classes  ?

• C09K 11/64 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing aluminium
• G01T 1/20 - Measuring radiation intensity with scintillation detectors
• G01T 1/202 - Measuring radiation intensity with scintillation detectors the detector being a crystal
• C09K 11/70 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing phosphorus
• C09K 11/77 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing rare earth metals

Abstract

The present invention is characterized by comprising: an acid leaching step for obtaining a leach liquid by causing leaching of, by means of an acid, a metal mixture at least containing vanadium and at least one type of a divalent or trivalent metal selected from nickel, cobalt, manganese, palladium, platinum, copper, and zinc; a complex generation step for adding an ammoniacal alkaline aqueous solution to the leach liquid for adjusting the pH to 10-12 and generating, in the alkaline aqueous solution, an ammine complex of a divalent or trivalent metal ion and an anion complex of a tetravalent and/or pentavalent vanadium ion; a divalent or trivalent metal recovery step for adding a carrier having a carboxyl group to the alkaline aqueous solution in which the ammine complex and the anion complex are generated, causing the divalent or trivalent metal ion in the ammine complex to be selectively adsorbed onto the carrier, and recovering the divalent or trivalent metal ion; and a vanadium recovery step for recovering vanadium from the anion complex contained in the alkaline aqueous solution after the divalent or trivalent metal ion is recovered.

IPC Classes  ?

• C22B 34/00 - Obtaining refractory metals
• C22B 34/22 - Obtaining vanadium
• C22B 3/24 - Treatment or purification of solutions, e.g. obtained by leaching by physical processes, e.g. by filtration, by magnetic means by adsorption on solid substances, e.g. by extraction with solid resins
• C22B 3/44 - Treatment or purification of solutions, e.g. obtained by leaching by chemical processes
• C22B 3/06 - Extraction of metal compounds from ores or concentrates by wet processes by leaching in inorganic acid solutions
• H01M 8/18 - Regenerative fuel cells, e.g. redox flow batteries or secondary fuel cells

Abstract

1H-NMR measurement, a second peak at a position corresponding to a chemical shift of from −2 ppm to −20 ppm with respect to a first peak attributed to gaseous hydrogen.

IPC Classes  ?

• C01B 3/00 - HydrogenGaseous mixtures containing hydrogenSeparation of hydrogen from mixtures containing itPurification of hydrogen
• C01B 32/00 - CarbonCompounds thereof
• C01B 32/318 - Preparation characterised by the starting materials
• C01B 32/336 - Preparation characterised by gaseous activating agents
• B01J 20/20 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising free carbonSolid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising carbon obtained by carbonising processes
• B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
• G01N 24/08 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance

Abstract

The present invention applies carbon nanotubes to catalyst particles, thereby providing catalyst particles which are usable in fluidized bed reactions, have high catalytic activity, and are easy to handle. The catalyst particles are carbon nanotube-coated catalyst particles which each comprise a carrier particle and a coating layer disposed on the surface of the carrier particle, wherein the carrier particles are flowable in fluidized beds and the coating layer comprises carbon nanotubes which have metal nanoparticles supported thereon and/or which have been doped with nitrogen or boron. The carbon nanotube-coated catalyst particles are flowable in fluidized bed reactions.

IPC Classes  ?

• B01J 23/755 - Nickel
• B01J 35/02 - Solids
• B01J 35/06 - Fabrics or filaments
• B01J 37/02 - Impregnation, coating or precipitation
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
• C01B 32/158 - Carbon nanotubes
• C01B 32/168 - After-treatment
• B01J 8/18 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes with fluidised particles
• B01J 21/04 - Alumina
• B01J 21/18 - Carbon
• B01J 23/745 - Iron
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
• C01B 3/04 - Production of hydrogen or of gaseous mixtures containing hydrogen by decomposition of inorganic compounds, e.g. ammonia
• C01B 21/02 - Preparation of nitrogen
• B82Y 40/00 - Manufacture or treatment of nanostructures

Abstract

The present invention provides a method for detection of an inflammatory reaction, which comprises using a transformant or transgenic non-human animal transfected with a vector comprising a promoter for a gene encoding an inflammatory cytokine, a gene encoding a reporter protein, a gene encoding the inflammatory cytokine, and a gene encoding a proteolytic signal sequence to thereby detect an inflammatory reaction induced upon inflammatory stimulation in the transformant or in the transgenic non-human animal.

IPC Classes  ?

• C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
• A01K 67/00 - Rearing or breeding animals, not otherwise provided forNew or modified breeds of animals
• C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression
• A01K 67/027 - New or modified breeds of vertebrates
• C12N 15/09 - Recombinant DNA-technology
• A61K 49/00 - Preparations for testing in vivo
• A61K 31/70 - CarbohydratesSugarsDerivatives thereof

Abstract

narrow: 0.4% or more and 15% or less.

IPC Classes  ?

• C01B 31/00 - Carbon; Compounds thereof
• H01M 4/90 - Selection of catalytic material
• B01J 37/08 - Heat treatment
• B01J 21/18 - Carbon
• H01M 8/10 - Fuel cells with solid electrolytes
• H01M 12/06 - Hybrid cellsManufacture thereof composed of a half-cell of the fuel-cell type and of a half-cell of the primary-cell type with one metallic and one gaseous electrode
• H01M 12/08 - Hybrid cellsManufacture thereof composed of a half-cell of a fuel-cell type and a half-cell of the secondary-cell type
• H01M 8/1004 - Fuel cells with solid electrolytes characterised by membrane-electrode assemblies [MEA]
• H01M 8/1018 - Polymeric electrolyte materials
• H01M 4/133 - Electrodes based on carbonaceous material, e.g. graphite-intercalation compounds or CFx
• H01M 4/583 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx
• H01M 4/587 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx for inserting or intercalating light metals
• C01B 32/05 - Preparation or purification of carbon not covered by groups , , ,

Abstract

An existing ultrasonic diagnostic device is used to obtain a color flow image of a target object whose stiffness is to be measured. At this time, a vibration exciter applies a micro vibration with a frequency of n/4 (n represents an odd number equal to or larger than 1) to the target object with respect to a burst frequency of an ultrasonic pulse to generate a shear elastic wave. As a result, a striped pattern corresponding to the stiffness of the target object caused by the shear elastic wave appears on a display of the ultrasonic diagnostic device as a shear elastic wave detection image.

IPC Classes  ?

• A61B 8/08 - Clinical applications
• A61B 8/14 - Echo-tomography
• A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
• A61B 8/06 - Measuring blood flow

Abstract

The present invention provides a useful medicament for the treatment and/or prophylaxis of a disease associated with the enhancement of OPN production including cancer, which comprises a compound of formula: 7, m, n, p, X, and Y are as defined in the specification, a pharmaceutically acceptable salt thereof.

IPC Classes  ?

• C07C 235/50 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
• C07C 235/48 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
• C07C 233/36 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
• C07C 233/78 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
• C07C 233/62 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
• C07D 309/08 - Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
• C07D 471/04 - Ortho-condensed systems
• C07D 213/81 - AmidesImides
• C07C 235/60 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho- position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
• C07C 237/22 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
• C07C 237/42 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
• C07D 209/14 - Radicals substituted by nitrogen atoms, not forming part of a nitro radical
• C07C 237/34 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
• A61K 31/437 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
• A61K 31/4045 - Indole-alkylaminesAmides thereof, e.g. serotonin, melatonin
• A61K 31/4409 - Non-condensed pyridinesHydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
• A61K 31/445 - Non-condensed piperidines, e.g. piperocaine
• A61K 31/40 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
• A61K 31/351 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
• A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
• A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
• A61K 31/397 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
• A61K 31/166 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon atom of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
• A61K 31/165 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
• C07D 205/04 - Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
• C07D 207/16 - Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
• C07D 211/60 - Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
• C07D 333/38 - Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

Provided is an implantable spacer that can be placed in a body and can be easily removed after placement. The implantable spacer includes a tube which is folded or bent at one or a plurality of positions to form partial sections adjacent to each other; fixing threads which are disposed along a direction transverse to the partial sections in order to maintain the shape of the tube; and a trigger thread for catching the fixing threads being in a releasable state.

IPC Classes  ?

• A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

Abstract

Disclosed is a nucleoside derivative of formulae (I-1) or a salt thereof: 3, B, X, Y, and k are described herein. Also provided are a 5′-phosphate ester and a 3′-phosphoramidite derivative of the nucleoside derivative and substrate solutions thereof. A polynucleotide is produced using the 5′-phosphate ester or 3′-phosphoramidite derivative of the nucleoside derivative. A library of the produced polynucleotide is used in a method of selecting a nucleic acid aptamer. Further provided is a vesicular endothelial growth factor binding agent of formula (i).

IPC Classes  ?

• C07H 19/20 - Purine radicals with the saccharide radical being esterified by phosphoric or polyphosphoric acids
• C07H 19/073 - Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
• C07H 19/10 - Pyrimidine radicals with the saccharide radical being esterified by phosphoric or polyphosphoric acids
• C12N 15/115 - Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith
• C07H 19/16 - Purine radicals
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• C07H 19/173 - Purine radicals with 2-deoxyribosyl as the saccharide radical
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof

Abstract

An electroconductive film for an actuator is formed from a gel composition including carbon nanofibers, an ionic liquid, and a polymer. The carbon nanofibers are produced with an aromatic mesophase pitch by melt spinning.

IPC Classes  ?

• H01L 41/08 - Piezo-electric or electrostrictive elements
• H01L 41/193 - Macromolecular compositions
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
• H01B 1/24 - Conductive material dispersed in non-conductive organic material the conductive material comprising carbon-silicon compounds, carbon, or silicon
• B82Y 15/00 - Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
• D01D 5/00 - Formation of filaments, threads, or the like
• D01F 9/145 - Carbon filamentsApparatus specially adapted for the manufacture thereof by decomposition of organic filaments from pitch or distillation residues
• B32B 27/08 - Layered products essentially comprising synthetic resin as the main or only constituent of a layer next to another layer of a specific substance of synthetic resin of a different kind
• B32B 27/20 - Layered products essentially comprising synthetic resin characterised by the use of special additives using fillers, pigments, thixotroping agents
• H01L 41/29 - Forming electrodes, leads or terminal arrangements

Abstract

First, the present invention involves adding a curing catalyst to a phenolic resin, polyvinyl alcohol, a pore-forming agent, and a cross-linking agent, and mixing, casting, heating, and drying the same. Next, the plate-shaped porous phenolic resin obtained thereby which has uniform consecutive macropores having an average pore diameter in the range of 3 to 35 μm and formed in a three-dimensional network pattern is immersed with an organic solvent. Thereafter, this block is extracted and pressure is applied thereto. It is possible to obtain plate-shaped activated carbon for use in an electrode of a power-storage device by carbonizing and activating a block which has undergone this procedure by keeping the same at an increased temperature.

IPC Classes  ?

• H01G 11/24 - Electrodes characterised by structural features of the materials making up or comprised in the electrodes, e.g. form, surface area or porosityElectrodes characterised by the structural features of powders or particles used therefor
• H01G 11/34 - Carbon-based characterised by carbonisation or activation of carbon
• H01G 11/42 - Powders or particles, e.g. composition thereof
• H01G 11/26 - Electrodes characterised by their structure, e.g. multi-layered, porosity or surface features
• H01G 11/50 - Electrodes characterised by their material specially adapted for lithium-ion capacitors, e.g. for lithium-doping or for intercalation
• H01G 11/86 - Processes for the manufacture of hybrid or EDL capacitors, or components thereof specially adapted for electrodes
• C01B 32/354 - After-treatment
• C01B 32/336 - Preparation characterised by gaseous activating agents

Abstract

Disclosed herein is an osteopontin production inhibitor capable of preventing a disease resulting from increased production of osteopontin. The osteopontin production inhibitor contains a dictyopyrone derivative or a dihydrodictyopyrone derivative as an active ingredient. The dictyopyrone derivative is preferably a compound represented by Chemical Formula 1 or 2, and the dihydrodictyopyrone derivative is preferably a compound represented by Chemical Formula 3 or 4.

IPC Classes  ?

• C07D 213/02 - Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
• A61K 31/45 - Non-condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
• A61K 31/366 - Lactones having six-membered rings, e.g. delta-lactones
• A61K 31/4412 - Non-condensed pyridinesHydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring

Abstract

An active material used for an electrochemical device utilizing Li ion conduction, and capable of improving cycle stability. The object is attained by providing an active material used for an electrochemical device utilizing Li ion conduction, including an active substance capable of absorbing and releasing a Li ion, and an Na ion conductor disposed on the surface of the active substance and having a polyanionic structure.

IPC Classes  ?

• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/58 - Selection of substances as active materials, active masses, active liquids of inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFySelection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
• H01G 11/06 - Hybrid capacitors with one of the electrodes allowing ions to be reversibly doped thereinto, e.g. lithium ion capacitors [LIC]
• H01G 11/30 - Electrodes characterised by their material
• H01G 11/50 - Electrodes characterised by their material specially adapted for lithium-ion capacitors, e.g. for lithium-doping or for intercalation

Abstract

There is provided a wiring substrate including an electrode including Cu or a Cu alloy, a plating film having a film including at least Pd, formed on the electrode, and a solder which is bonded onto the plating film by heating, has a melting point of lower than 140° C., and includes Pd dissolved therein, a Pd concentrated layer being absent between the solder and the electrode.

IPC Classes  ?

• H05K 1/09 - Use of materials for the metallic pattern
• H05K 3/10 - Apparatus or processes for manufacturing printed circuits in which conductive material is applied to the insulating support in such a manner as to form the desired conductive pattern
• B23K 1/19 - Soldering, e.g. brazing, or unsoldering taking account of the properties of the materials to be soldered
• B23K 1/00 - Soldering, e.g. brazing, or unsoldering
• C25D 7/00 - Electroplating characterised by the article coated
• B23K 35/26 - Selection of soldering or welding materials proper with the principal constituent melting at less than 400°C
• C22C 13/02 - Alloys based on tin with antimony or bismuth as the next major constituent
• H05K 3/24 - Reinforcing of the conductive pattern
• B23K 1/008 - Soldering within a furnace

Abstract

2/g or more, and a porosity of 15% or more, each of which is measured by a mercury intrusion method at room temperature, the polyethylene porous film being obtained by forming pores only by drawing a film containing an ultrahigh molecular weight polyethylene having a viscosity average molecular weight of from 1 million to 15 million and a polyethylene having a weight average molecular weight of from 10,000 to 800,000 at a mass ratio of from 50:50 to 99:1. The polyethylene porous film is produced by molding a film using a mixture of the ultrahigh weight polyethylene and the polyethylene having a weight average molecular weight of from 10,000 to 800,000, biaxially drawing the film, then heat-treating and redrawing the film to form pores in the film.

IPC Classes  ?

• B29C 55/02 - Shaping by stretching, e.g. drawing through a dieApparatus therefor of plates or sheets
• B01D 71/26 - Polyalkenes
• H01M 2/16 - Separators; Membranes; Diaphragms; Spacing elements characterised by the material
• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B32B 3/26 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layerLayered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a layer with cavities or internal voids
• B32B 27/08 - Layered products essentially comprising synthetic resin as the main or only constituent of a layer next to another layer of a specific substance of synthetic resin of a different kind
• B32B 27/32 - Layered products essentially comprising synthetic resin comprising polyolefins
• B29K 23/00 - Use of polyalkenes as moulding material
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries

Abstract

TASK It is an object of the present invention to provide a hydrogel having excellent mechanical properties and capable of being produced simply by using and mixing an industrially easily obtainable polymer having high versatility and clay particles, and to provide a method of producing the hydrogel. MEANS OF SOLVING THE PROBLEM A hydrogel-forming composition is characterized by containing a polyelectrolyte (A), clay particles (B), and a dispersant (C) for the clay particles.

IPC Classes  ?

• C08K 3/32 - Phosphorus-containing compounds
• C08K 3/34 - Silicon-containing compounds
• C08J 3/075 - Macromolecular gels

Abstract

TASK It is an object of the present invention to provide a hydrogel having excellent mechanical properties and capable of being produced simply by using and mixing an industrially easily obtainable polymer having high versatility and clay particles, and to provide a method of producing the hydrogel. MEANS OF SOLVING THE PROBLEM A hydrogel-forming composition is characterized by containing a polyelectrolyte (A), clay particles (B), and a dispersant (C) for the clay particles.

IPC Classes  ?

• C08L 33/06 - Homopolymers or copolymers of esters of esters containing only carbon, hydrogen, and oxygen, the oxygen atom being present only as part of the carboxyl radical
• C08J 3/075 - Macromolecular gels
• C08K 3/34 - Silicon-containing compounds
• C08K 3/32 - Phosphorus-containing compounds
• C08K 3/20 - OxidesHydroxides

Abstract

2/g, a micropore volume within a range of 0.4 to 1.0 mL/g, and an average micropore width within a range of 0.7 to 1.2 nm. Provided is an activated carbon for an electrode of a power storage device suitable for an electric double layer capacitor that has high capacitance during charging and discharging at high current density and excellent endurance against charging at a high voltage of 3 V or more and a lithium-ion capacitor having excellent endurance against charging at a high voltage of 4 V or more.

IPC Classes  ?

• H01G 9/00 - Electrolytic capacitors, rectifiers, detectors, switching devices, light-sensitive or temperature-sensitive devicesProcesses of their manufacture
• H01G 9/04 - Electrodes
• H01G 9/145 - Liquid electrolytic capacitors
• C01B 31/00 - Carbon; Compounds thereof
• H01G 11/34 - Carbon-based characterised by carbonisation or activation of carbon
• H01G 11/06 - Hybrid capacitors with one of the electrodes allowing ions to be reversibly doped thereinto, e.g. lithium ion capacitors [LIC]
• H01G 11/86 - Processes for the manufacture of hybrid or EDL capacitors, or components thereof specially adapted for electrodes
• H01G 11/24 - Electrodes characterised by structural features of the materials making up or comprised in the electrodes, e.g. form, surface area or porosityElectrodes characterised by the structural features of powders or particles used therefor
• C01B 32/336 - Preparation characterised by gaseous activating agents

Abstract

There is provided a metal fine particle association suitably applied to an electrode catalyst to achieve even higher output leading to reduction in amount of the catalyst used, and a process for producing the same, that is, a metal fine particle association including a plurality of metal fine particles that have a mean particle diameter of 1 nm to 10 nm and are associated to form a single assembly, an association mixture including the metal fine particle association and a conductive support; a premix for forming an association, including metal fine particles, a metal fine particle dispersant made of a hyperbranched polymer, and a conductive support; and a method for producing the association mixture.

IPC Classes  ?

• H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
• H01M 4/92 - Metals of platinum group
• H01M 4/88 - Processes of manufacture
• H01M 4/90 - Selection of catalytic material
• B22F 1/00 - Metallic powderTreatment of metallic powder, e.g. to facilitate working or to improve properties
• B22F 9/24 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using chemical processes with reduction of metal compounds starting from liquid metal compounds, e.g. solutions
• C22C 5/04 - Alloys based on a platinum group metal
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
• H01M 8/1007 - Fuel cells with solid electrolytes with both reactants being gaseous or vaporised

Abstract

A crystallization substrate of the present invention includes a noble metal vapor-deposited film having an absorbance in a 500 to 1,000 nm wavelength range and formed in all or part of one surface of the substrate. The noble metal vapor-deposited film has an average thickness of 0.1 to 60 nm. The noble metal vapor-deposited film is a continuous film with a pit formed by vapor deposition in part of the film and surrounded by the continuous film.

IPC Classes  ?

• C30B 29/58 - Macromolecular compounds
• B01J 19/08 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor
• C30B 7/00 - Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
• C12N 9/36 - Hydrolases (3.) acting on glycosyl compounds (3.2) acting on beta-1, 4 bonds between N-acetylmuramic acid and 2-acetylamino 2-deoxy-D-glucose, e.g. lysozyme
• C23C 14/18 - Metallic material, boron or silicon on other inorganic substrates

Abstract

A wiring substrate includes an electrode including Cu or a Cu alloy, and a plated film including an electroless nickel-plated layer formed on the electrode and an electroless gold-plated layer formed on the electroless nickel-plated layer. The electroless nickel-plated layer is formed by co-precipitation of Ni, P, Bi, and S, the electroless nickel-plated layer includes a content of P of 5% by mass or more and less than 10% by mass, a content of Bi of 1 ppm by mass to 1,000 ppm by mass, and a content of S of 1 ppm by mass to 2,000 ppm by mass, and a mass ratio of the content of S to the content of Bi (S/Bi) is more than 1.0.

IPC Classes  ?

• B05D 5/12 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain a coating with specific electrical properties
• B28B 19/00 - Machines or methods for applying the material to surfaces to form a permanent layer thereon
• C23C 18/00 - Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coatingContact plating
• H01C 17/06 - Apparatus or processes specially adapted for manufacturing resistors adapted for coating resistive material on a base
• H05K 3/00 - Apparatus or processes for manufacturing printed circuits
• H05K 1/09 - Use of materials for the metallic pattern
• C23C 18/36 - Coating with one of iron, cobalt or nickelCoating with mixtures of phosphorus or boron with one of these metals using reducing agents using hypophosphites
• C23C 18/44 - Coating with noble metals using reducing agents
• C23C 18/16 - Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coatingContact plating by reduction or substitution, i.e. electroless plating
• H05K 3/24 - Reinforcing of the conductive pattern
• C23C 18/50 - Coating with alloys with alloys based on iron, cobalt or nickel

Abstract

Provided are a support for supporting a metal, a metal-supported catalyst, a methanation reaction apparatus, and a method relating thereto that realize effective methanation of carbon monoxide. The support for supporting a metal includes a carbonized material obtained by carbonizing raw materials containing an organic substance and a metal, in which the support is used for supporting a metal that exhibits a catalytic activity for a methanation reaction of carbon monoxide. The metal-supported catalyst includes: a support formed of a carbonized material obtained by carbonizing raw materials containing an organic substance and a metal; and a metal that exhibits a catalytic activity for a methanation reaction of carbon monoxide, the metal being supported on the support.

IPC Classes  ?

• C07C 1/04 - Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon from oxides of carbon from carbon monoxide with hydrogen
• B01J 23/755 - Nickel
• C01B 3/58 - Separation of hydrogen or hydrogen containing gases from gaseous mixtures, e.g. purification by contacting with solidsRegeneration of used solids including a catalytic reaction
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
• B01J 23/75 - Cobalt

Abstract

Provided is a negative-electrode active material, which is capable of constituting a lithium ion secondary cell exhibiting excellent cell characteristics. The negative-electrode active material for a lithium ion secondary cell of the invention includes a mixed material of silicon oxide particles composed of silicon oxide and rod-shaped iron oxide particles composed of iron oxide. It is preferable to use iron oxide particles having a plurality of pores in a surface, and an electrode reaction is effectively carried out.

IPC Classes  ?

• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• C01G 49/06 - Ferric oxide [Fe2O3]
• H01M 4/485 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of mixed oxides or hydroxides for inserting or intercalating light metals, e.g. LiTi2O4 or LiTi2OxFy
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

A hydrogel having mechanical properties and capable of being produced simply by using and mixing an industrially obtainable polymer having high versatility and clay particles, and to provide a method of producing the hydrogel. A hydrogel-forming composition is characterized by containing a polyelectrolyte, clay particles, and a dispersant for the clay particles.

IPC Classes  ?

• C08L 33/06 - Homopolymers or copolymers of esters of esters containing only carbon, hydrogen, and oxygen, the oxygen atom being present only as part of the carboxyl radical
• C08K 3/32 - Phosphorus-containing compounds
• C08K 3/34 - Silicon-containing compounds
• C08K 3/20 - OxidesHydroxides

Abstract

A hydrogel having excellent mechanical properties and capable of being produced simply by using and mixing an industrially easily obtainable polymer having high versatility and clay particles, and to provide a method of producing the hydrogel. A hydrogel-forming composition is characterized by containing a polyelectrolyte, clay particles, and a dispersant for the clay particles.

IPC Classes  ?

• C08K 3/32 - Phosphorus-containing compounds
• C08K 3/34 - Silicon-containing compounds

Abstract

Provided is a method of producing a carbon catalyst having an improved activity. The method of producing carbon catalyst including a carbonization step of carbonizing raw materials containing an organic compound as a carbon source, a metal, and an electrically conductive carbon material to produce a carbonized material; a metal impregnation step of impregnating the carbonized material with a metal; and a heat treatment step of subjecting the carbonized material impregnated with the metal to a heat treatment.

IPC Classes  ?

• B01J 20/00 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof
• H01M 4/90 - Selection of catalytic material

Abstract

A frictional-force variable compact of the invention includes: a first surface; a second surface; insulation portion; and an electroconductive portion electrically conducting the first surface to the second surface.

IPC Classes  ?

• B32B 3/24 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a discontinuous layer, i.e. apertured or formed of separate pieces of material characterised by an apertured layer, e.g. of expanded metal
• B32B 7/02 - Physical, chemical or physicochemical properties
• F16F 7/08 - Vibration-dampersShock-absorbers with friction surfaces rectilinearly movable along each other
• C10M 171/00 - Lubricating compositions characterised by purely physical criteria, e.g. containing as base-material, thickener or additive, ingredients which are characterised exclusively by their numerically specified physical properties, i.e. containing ingredients which are physically well defined but for which the chemical nature is either unspecified or only very vaguely indicated
• B32B 3/26 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layerLayered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a layer with cavities or internal voids

Abstract

A carbon catalyst which has high catalytic activity and can achieve high catalyst performance is provided. The carbon catalyst comprises nitrogen. The energy peak area ratio of the first nitrogen atom whose electron in the 1s orbital has a binding energy of 398.5±1.0 eV to the second nitrogen atom whose electron in the 1s orbital has a binding energy of 401±1.0 eV (i.e., the value of (the first nitrogen atom)/(the second nitrogen atom)) of the nitrogen introduced into the catalyst is 1.2 or less.

IPC Classes  ?

• H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
• C01B 31/02 - Preparation of carbon; Purification
• H01G 9/26 - Structural combinations of electrolytic capacitors, rectifiers, detectors, switching devices, light-sensitive or temperature-sensitive devices with each other
• H01G 11/38 - Carbon pastes or blendsBinders or additives therein
• H01M 4/587 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx for inserting or intercalating light metals
• H01M 4/88 - Processes of manufacture
• H01M 4/90 - Selection of catalytic material
• H01M 4/96 - Carbon-based electrodes
• H01M 8/1018 - Polymeric electrolyte materials
• H01G 11/34 - Carbon-based characterised by carbonisation or activation of carbon
• H01M 8/10 - Fuel cells with solid electrolytes

Abstract

Provided are a carbon catalyst for hydrogen production having an excellent catalytic activity, a production method therefor, and a method of producing hydrogen using the catalyst. The carbon catalyst for hydrogen production is a carbon catalyst, which is obtained by carbonizing a raw material including an organic substance and a transition metal, the catalyst being used for hydrogen production by thermal decomposition of a hydrocarbon compound and/or an oxygen-containing organic compound. Further, the carbon catalyst for hydrogen production may be obtained by loading an alkaline earth metal on a carbonized material produced by the carbonization.

IPC Classes  ?

• B01J 23/755 - Nickel
• B01J 23/745 - Iron
• C01B 3/26 - Production of hydrogen or of gaseous mixtures containing hydrogen by decomposition of gaseous or liquid organic compounds of hydrocarbons using catalysts
• B01J 23/75 - Cobalt
• B01J 21/18 - Carbon
• B01J 23/78 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with alkali- or alkaline earth metals or beryllium
• B01J 23/34 - Manganese
• B01J 23/02 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the alkali- or alkaline earth metals or beryllium
• B01J 23/74 - Iron group metals
• B01J 37/06 - Washing
• B01J 37/08 - Heat treatment
• C01B 3/22 - Production of hydrogen or of gaseous mixtures containing hydrogen by decomposition of gaseous or liquid organic compounds

Abstract

Provided is a carbon catalyst having an improved catalytic activity, a production method therefor, and an electrode and a battery which use the carbon catalyst. The carbon catalyst is obtained by carbonizing a raw material including an organic substance containing a nitrogen atom and metals, and includes iron and/or cobalt, and copper as the metals. Further, the carbon catalyst has a crystallinity of 41.0% or less, which is determined by X-ray diffractometry, a nitrogen atom-to-carbon atom ratio of 0.7 or more, which is determined by X-ray photoelectronic spectrometry, and an oxygen reduction-starting potential of 0.774 V (vs. NHE) or more.

IPC Classes  ?

• H01M 4/13 - Electrodes for accumulators with non-aqueous electrolyte, e.g. for lithium-accumulatorsProcesses of manufacture thereof
• H01M 4/133 - Electrodes based on carbonaceous material, e.g. graphite-intercalation compounds or CFx
• H01M 4/1393 - Processes of manufacture of electrodes based on carbonaceous material, e.g. graphite-intercalation compounds or CFx
• H01M 4/88 - Processes of manufacture
• B01J 29/00 - Catalysts comprising molecular sieves
• B01J 21/18 - Carbon
• B01J 23/40 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of noble metals of the platinum group metals
• H01M 4/90 - Selection of catalytic material
• H01M 4/96 - Carbon-based electrodes
• H01M 8/10 - Fuel cells with solid electrolytes

Abstract

A method of manufacturing a PTFE stretched film that has higher tensile strength at its breaking point. In the method, a resin composition is obtained by mixing an emulsion of PTFE (A) with a number average molecular weight of 5×106 or more and an emulsion of PTFE (B) with a number average molecular weight of 1×106 to 4×106 so that the solid content ratio (A/B) of the PTFE (A) and the PTFE (B) is 99/1 to 10/90. The mixed emulsion is subjected to compression molding in a melted state under a reduced-pressure atmosphere to obtain a film.

IPC Classes  ?

• B29C 43/14 - Compression moulding, i.e. applying external pressure to flow the moulding materialApparatus therefor of articles of definite length, i.e. discrete articles in several steps
• B29C 55/00 - Shaping by stretching, e.g. drawing through a dieApparatus therefor
• B29C 55/12 - Shaping by stretching, e.g. drawing through a dieApparatus therefor of plates or sheets multiaxial biaxial
• B29C 55/16 - Shaping by stretching, e.g. drawing through a dieApparatus therefor of plates or sheets multiaxial biaxial simultaneously
• B29C 43/00 - Compression moulding, i.e. applying external pressure to flow the moulding materialApparatus therefor
• C08J 5/18 - Manufacture of films or sheets
• C08L 27/18 - Homopolymers or copolymers of tetrafluoroethene
• B29C 47/92 - Measuring, controlling or regulating
• B29C 43/36 - Moulds for making articles of definite length, i.e. discrete articles
• B29C 47/00 - Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor (extrusion blow-moulding B29C 49/04)
• B29C 43/56 - Compression moulding under special conditions, e.g. vacuum
• B29K 27/18 - PTFE, i.e. polytetrafluorethene

Abstract

A method for producing an ultra-high-molecular-weight polyethylene porous membrane, including: a step of molding a film using an ultra-high-molecular-weight polyethylene raw material; a step of biaxially stretching the obtained film in X-axis and Y-axis directions at a temperature of from a melting point of the film to 180° C.; and a pore-forming step of stretching the stretched film along at least one axis of the X-axis and Y-axis at from 142° C. to 170° C. Alternatively, a method for producing an ultra-high-molecular-weight polyethylene film, including: a step of molding a film by two steps of press-molding and roll-molding using an ultra-high-molecular-weight polyethylene raw material; and a step of biaxially stretching the film obtained in the above step, in X-axis and Y-axis directions at a temperature of from a melting point of the film to 180° C.

IPC Classes  ?

• B29C 67/00 - Shaping techniques not covered by groups , or
• B29D 7/01 - Films or sheets
• B29C 55/00 - Shaping by stretching, e.g. drawing through a dieApparatus therefor
• B29C 55/14 - Shaping by stretching, e.g. drawing through a dieApparatus therefor of plates or sheets multiaxial biaxial successively
• B29C 55/18 - Shaping by stretching, e.g. drawing through a dieApparatus therefor of plates or sheets by squeezing between surfaces, e.g. rollers
• C08J 5/18 - Manufacture of films or sheets
• B29K 23/00 - Use of polyalkenes as moulding material
• B29K 105/04 - Condition, form or state of moulded material cellular or porous

Abstract

An electrode for use in a fuel cell comprises a flexible carbon-fiber nonwoven fabric and a fuel cell catalyst, such as a metal catalyst or a carbon alloy catalyst, supported on the surfaces of the carbon fibers constituting the flexible carbon-fiber nonwoven fabric. The flexible carbon-fiber nonwoven fabric is formed by carbonizing a nonwoven fabric obtained by electrospinning a composition containing: an electrospinnable macromolecular substance; an organic compound that is different from the macromolecular substance; and a transition metal. This structure allows the provision of an electrode, for use in a fuel cell, which uses a flexible carbon-fiber nonwoven fabric as a substrate and combines the functions of a gas-diffusion layer and an electrocatalyst layer.

IPC Classes  ?

• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/90 - Selection of catalytic material
• H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
• H01M 8/10 - Fuel cells with solid electrolytes

Abstract

Provided is a carbon catalyst for a cathode of a direct fuel cell, which selectively promotes an oxygen reduction reaction even when crossover of a fuel compound occurs. The carbon catalyst for a cathode of a direct fuel cell exhibits an oxygen-reducing catalytic activity in an electrolytic solution containing a fuel compound for the direct fuel cell, and exhibits substantially no catalytic activity to oxidize the fuel compound in the electrolytic solution.

IPC Classes  ?

• H01M 8/22 - Fuel cells in which the fuel is based on materials comprising carbon or oxygen or hydrogen and other elementsFuel cells in which the fuel is based on materials comprising only elements other than carbon, oxygen or hydrogen

Abstract

3/g or more, and a ratio of a total mesoporous volume to a total microporous volume per unit weight of 5 or more. In addition, the hydrogen-storing carbon material may have a nitrogen content of 0.5 wt % or more and less than 20 wt %. In addition, the hydrogen-storing carbon material may have a stable potential of −1.28 V or more when a cathode current with respect to the hydrogen-storing carbon material is held at 1,000 mA/g in electrochemical measurement by chronopotentiometry involving using the hydrogen-storing carbon material in a working electrode in a three-electrode method.

IPC Classes  ?

• H01B 1/06 - Conductors or conductive bodies characterised by the conductive materialsSelection of materials as conductors mainly consisting of other non-metallic substances

Abstract

1,580) in a Raman spectrum of 0.3 or more and 1.0 or less. In addition, the support for carrying a catalyst may be obtained by carbonizing the raw materials to obtain a carbonized material, subjecting the carbonized material to a metal removal treatment, and subjecting the resultant to a heat treatment.

IPC Classes  ?

• H01M 4/13 - Electrodes for accumulators with non-aqueous electrolyte, e.g. for lithium-accumulatorsProcesses of manufacture thereof
• H01M 4/90 - Selection of catalytic material
• H01M 4/92 - Metals of platinum group
• C01B 31/04 - Graphite
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
• H01M 4/66 - Selection of materials

Abstract

3 particles that generate a conversion electrode reaction, the binder component is a mixture of polyamide acid and partially imidized polyamide acid. The electrode layer is configured so that a concentration of the binder component decreases as distanced from the current collector.

IPC Classes  ?

• H01M 4/52 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
• H01M 4/131 - Electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
• H01M 4/1391 - Processes of manufacture of electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

Disclosed is a method for producing a ultra high molecular weight polyethylene film, which comprises: a step of forming a film using a ultra high molecular weight polyethylene material; a step of biaxially drawing the film obtained in the step in the x-axis direction and in the y-axis direction at a temperature not less than the melting point of the ultra high molecular weight polyethylene material; and the step of shrinking the film along at least one of the x-axis direction and y-axis direction. By this method, a ultra high molecular weight polyethylene film having high tensile strength at break, high tear strength and excellent uniformity can be efficiently produced at low cost.

IPC Classes  ?

• B29C 55/16 - Shaping by stretching, e.g. drawing through a dieApparatus therefor of plates or sheets multiaxial biaxial simultaneously
• C08J 5/18 - Manufacture of films or sheets
• B29C 55/00 - Shaping by stretching, e.g. drawing through a dieApparatus therefor
• B29C 55/10 - Shaping by stretching, e.g. drawing through a dieApparatus therefor of plates or sheets multiaxial
• B29C 55/12 - Shaping by stretching, e.g. drawing through a dieApparatus therefor of plates or sheets multiaxial biaxial
• B29C 55/14 - Shaping by stretching, e.g. drawing through a dieApparatus therefor of plates or sheets multiaxial biaxial successively
• B29K 23/00 - Use of polyalkenes as moulding material

Abstract

Disclosed is a compound characterized by comprising a linker, an oxygen-concentration-responsive phosphorophore which is linked to a first end of the linker, and a fluorophore which is lined to a second end of the linker. In the compound, it is preferred that the triplet level of the phosphorophore be lower than that of the fluorophore. The compound can be used as an oxygen-responsive luminescent probe.

IPC Classes  ?

• C09K 11/00 - Luminescent, e.g. electroluminescent, chemiluminescent, materials
• C09K 11/87 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing platinum group metals

Abstract

In a schlieren optical system, a laser beam is passed through the jet flow and the ambient around the jet flow, and a high speed sampling is performed using a high speed photo sensor while displacing measurement points. The value obtained by sampling represents a result of the optical path caused curved by a density gradient generated in an arc-shape from the center of the jet flow. The value is subjected to a high speed discrete Fourier transform and decomposed into frequency components which constitute the noise. Thereafter, Abel inversion is performed on data belonging to a particular frequency to obtain a density gradient in the radial direction from the center of the jet flow. The obtained density gradient is visualized in a graph display, so that the position of the sound source and the state of the jet flow can be accurately grasped.

IPC Classes  ?

• G01N 21/41 - RefractivityPhase-affecting properties, e.g. optical path length