Provided are a health risk monitoring method and apparatus for subsurface soil pollution of impervious surface in urban factories. The method includes the following steps: calculating linkage degree between a target chemical industrial park and the town according to a distance between the target chemical industrial park and each town; and determining a health risk of population affected by the target chemical industrial park by using the linkage degree. The health risk of target population is determined by using the linkage degree, which is helpful for the supervision department to take effective countermeasures in time to ensure public health.
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
The present invention discloses a method for nitrogen removal of wastewater, which achieves the perfect combination of COD removal (Fenton oxidation) and nitrogen removal (Feammox) of wastewater, thereby avoiding the waste of reagents in traditional Fenton oxidation treatment of wastewater.
Disclosed in the present invention is a method for conversion of a back image into a spinal X-ray image based on a conditional generative adversarial network, comprising the following steps: collecting a back image and a spinal X-ray image, and establishing a training set database; using LabelMe to label and preprocess the back image and the spinal X-ray image in the database; using the preprocessed X-ray image to train an object detection model; processing all data sets, and performing image alignment on paired images of the cropped back image and X-ray image of a same patient; training a conditional generative adversarial network model based on a sliding window self-attention mechanism, taking the aligned back image as an input, generating an output matching the X-ray image, and predicting a scoliosis condition; and using internal and external data sets to test the conversion performance of the model. The present invention can be applied to remote diagnosis and treatment and follow-up of spinal deformity, and enhances health monitoring for patients with spinal deformity by doctors.
Disclosed in the present invention is a method for converting a back photo into a spine X-ray image based on a stable diffusion model. A back photo is inputted into a stable diffusion model, alignment processing is performed on the back photo and an X-ray image, the X-ray image is inputted into an encoder, UNet is used for denoising of pure noise, a feature vector of the back photo extracted by means of a fully connected layer is mapped to an intermediate layer of the UNet by means of cross-attention, and finally the generated X-ray image is used to automatically calculate a Cobb angle to predict the illness state of scoliosis. Data required in the present invention is only a back photo captured by a household smartphone or camera, and an X-ray device does not need to be used, thereby reducing the medical treatment cost and the radiation risk; an image similar to an X-ray image is generated by using a stable diffusion model algorithm, thereby improving the image conversion quality and accuracy; and detection of the back spine skeletal structure can be realized, thereby facilitating assessment and prevention of diseases such as spinal deformity.
Disclosed are a nanobody targeting influenza A virus nucleoprotein and an application thereof, and a nucleic acid encoding the nanobody. The present disclosure obtains one nanobody targeting influenza A virus nucleoprotein through construction of a nanobody phage library and phage screening technology. The nanobody targeting influenza A virus nucleoprotein is a VHH antibody fragment having an amino acid sequence shown in SEQ ID NO:1-SEQ ID NO:2. The nanobody in the present disclosure can specifically bind to influenza A virus nucleoprotein, and can be applied to the detection and analysis of influenza A virus, and has broad application prospects in the fields of early warning of the epidemic or outbreak of influenza A virus, as well as the detection of influenza A virus in the environment or human body.
An apparatus for detecting and identifying foreign matter in a shallow stratum on the basis of distributed acoustic wave sensing. The apparatus comprises: a vibration-sensitive optical cable (1), a distributed acoustic wave sensing demodulator (2), a seismic source system (3), a vibration data processing unit (4), a velocity structure inversion unit (5) and an artificial intelligence positioning and identification unit (6), wherein when performing detection and identification, the distributed acoustic wave sensing demodulator (2) transmits a vibration signal to the vibration data processing unit (4) for preprocessing, so as to acquire a waveform signal; the velocity structure inversion unit (5) inverts a shallow stratum underground velocity structure on the basis of the waveform signal, so as to acquire the shallow stratum underground velocity structure; the location of foreign matter in a shallow stratum is identified by means of the underground velocity structure and an abnormal waveform; and the type of the foreign matter in the shallow stratum is identified by means of the artificial intelligence positioning and identification unit (6), image noise reduction and object segmentation. In the present application, a vibration signal is acquired by using a distributed optical cable acoustic wave sensing method, velocity imaging is performed on a shallow stratum velocity structure, and the positioning of shallow stratum underground foreign matter and the identification of the type of the foreign matter are realized by utilizing artificial intelligence. The present application further relates to a method for detecting and identifying foreign matter in a shallow stratum on the basis of distributed acoustic wave sensing.
Disclosed are a preparation method and application of a single-chain antibody fragment targeting SARS-COV-2 nucleocapsid protein, aiming to provide a single-chain antibody fragment with high affinity and strong specificity. The present disclosure obtains three single-chain antibody fragments targeting SARS-COV-2 nucleocapsid protein through construction of a nanobody phage library and phage screening technology. The single-chain antibody fragment consists of a heavy chain variable region, a 15aa connecting peptide, and a light chain variable region connected in sequence, and has an amino acid sequence shown in SEQ ID NO: 1-SEQ ID NO: 3. The single-chain antibody fragment in the present disclosure has excellent binding performance and specificity with the SARS-COV-2 nucleocapsid protein, can be applied to a variety of immunoassay platforms of the SARS-COV-2, and has broad application prospects in the field of SARS-COV-2 detection.
Disclosed are a device and method for detecting and identifying shallow-stratum foreign objects based on distributed acoustic sensing. The device includes a vibrating sensitivity-enhanced fiber optic cable, a distributed acoustic sensing demodulator, a vibrator system, a vibration data processing unit, a velocity structure inversion unit and an AI-aided locating and identification unit. The distributed acoustic sensing demodulator transmits vibration signals to the vibration data processing unit for preprocessing to obtain waveform signals; the velocity structure inversion unit performs inversion to obtain the shallow-stratum underground velocity structure; positions of shallow-stratum foreign objects are identified through the underground velocity structure and abnormal waveforms; and the types of shallow-stratum foreign objects are identified. A distributed acoustic sensing method for fiber optic cables is used to obtain vibration signals, velocity imaging is performed on a shallow-stratum velocity structure, and AI is utilized to achieve locating and type identification of shallow-stratum underground foreign objects.
Provided in the present application is a fast modular multiplication system based on base transformation. The fast modular multiplication system comprises: a precomputation layer, which is used for performing base transformation processing on a first modular multiplication input A and a second modular multiplication input B, which are inputted; a polynomial modular multiplication layer, which is used for sequentially performing grouped multiplication processing and recombination and reduction processing on the first modular multiplication input A and the second modular multiplication input B which have been subjected to base transformation processing; an iterative reduction layer, which is used for sequentially performing several instances of mapping and wiring processing and accumulation processing on a polynomial which has been subjected to the recombination and reduction processing and includes the first modular multiplication input A and the second modular multiplication input B; and a radix restoration layer, which is used for converting, from a radix-X to binary, a polynomial which has been subjected to the last instance of accumulation processing and includes the first modular multiplication input A and the second modular multiplication input B. In the present application, the fast modular multiplication system reduces the usage of circuit hardware, and thus the area of a circuit is saved on, and more advantages in terms of both area and speed exist compared with a conventional modular multiplication system.
G06F 7/72 - Methods or arrangements for performing computations using a digital non-denominational number representation, i.e. number representation without radixComputing devices using combinations of denominational and non-denominational quantity representations using residue arithmetic
10.
Preparation method and application of nanobody targeting dengue virus NS1 protein
Disclosed are a preparation method and application of a nanobody targeting dengue virus NS1 protein. The nanobody targeting dengue virus NS1 protein is a VHH antibody, which is obtained by constructing a nanobody phage library through phage screening technology, and has an amino acid sequence shown in SEQ ID NO: 1. The nanobody in the present disclosure exhibits high affinity and specificity when being bound to the dengue virus NS1 protein, and has advantages of good stability and low cost compared with monoclonal antibodies. Therefore, the nanobody in the present disclosure can be produced on a large scale, and has bright application prospects in the field of dengue virus detection and analysis.
The present invention discloses an irradiation-resistant GaN HEMT with decoupling reverse conduction capability and a fabricating method thereof. First gate region metal and second gate region metal are sectionally distributed on a p-type gallium nitride layer in a gate region of the transistor, where the first gate region metal consists of first Schottky metal layers and second ohmic metal layers, and the second gate region metal only consists of a second Schottky metal layer; dielectric layers are filled between the first gate region metal and the second gate region metal, an interconnection metal layer is arranged above the first gate region metal and is connected to an interconnection metal layer above a source to form a reverse freewheeling diode; and gate metal layers are arranged above the second gate region metal and are used as a real gate of the transistor.
H01L 27/06 - Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including integrated passive circuit elements with at least one potential-jump barrier or surface barrier the substrate being a semiconductor body including a plurality of individual components in a non-repetitive configuration
H01L 29/20 - Semiconductor bodies characterised by the materials of which they are formed including, apart from doping materials or other impurities, only AIIIBV compounds
A photoresist-free optical patterning method for colloidal nanocrystals in a green solvent is provided. A photosensitive ligand structurally similar to the green solvent is introduced to successfully disperse nanocrystals in the green solvent and complete direct photolithography on the nanocrystals. Photosensitive nanocrystals obtained through ligand exchange can be effectively dispersed in the green solvent to absorb spectra emitted by the green solvent, thereby preserving about 90% of photoluminescence quantum yield (PLQY) while keeping the morphology and size unchanged. The present invention solves the problem that nanocrystals cannot be subject to direct photolithography in the green solvent, and is expected to be applied to the commercialization of nanocrystals in the field of electroluminescent and photoluminescent quantum dot displays.
A method for treating refractory organic pollutants in wastewater including: synthesizing an aluminum-based metal oxide with a high specific surface area and surface hydroxyl content; mixing organic pollutants, an oxidant, and chloride ions to yield a reaction solution; adjusting an initial pH value of the reaction solution; and adding the aluminum-based metal oxide to the reaction solution.
The present invention relates to a sound wave absorption structure, a sound transmission apparatus, a device and a manufacturing method. The acoustic wave absorption structure comprises a plurality of acoustic wave absorption materials arranged at intervals along a preset axis. The distance between every two adjacent acoustic wave absorption materials in the direction of extension of the preset axis meets a preset condition. Each acoustic wave absorption material has a first inclination angle relative to the preset axis, an acoustic wave incident to each acoustic wave absorption material has a second inclination angle relative to the preset axis, and when the first inclination angle and the second inclination angle are symmetrical about the preset axis, the first inclination angle is the absorption inclination angle of the acoustic wave absorption material. At least some of the acoustic wave absorption materials are configured to be inclinedly arranged relative to the preset axis within a range where the absorption inclination angle of the at least some of the acoustic wave absorption materials is increased/decreased by a preset angle. The acoustic wave absorption structure can achieve sound absorption and noise reduction in a target direction.
A wide bandgap semiconductor structure for an irradiation characteristic test includes a substrate with metal plates and a wide bandgap semiconductor part. The wide bandgap semiconductor part includes a gallium nitride layer, a barrier layer, P-type gallium nitride layers, source ohmic metal layers, and drain ohmic metal layers. The P-type gallium nitride layers are connected to a gate interconnection metal layer via gate metal layers and metal lead wires. A gate top metal layer is provided on the gate interconnection metal layer. Each source ohmic metal layer is provided with a source interconnection metal layer and source top metal layers. Each drain ohmic metal layer is provided with a drain interconnection metal layer and drain top metal layers. The wide bandgap semiconductor part is connected to the metal plates through the source top metal layers, the drain top metal layers, and the gate top metal layer.
H10D 30/47 - FETs having zero-dimensional [0D], one-dimensional [1D] or two-dimensional [2D] charge carrier gas channels having 2D charge carrier gas channels, e.g. nanoribbon FETs or high electron mobility transistors [HEMT]
H01L 21/66 - Testing or measuring during manufacture or treatment
H10D 62/85 - Semiconductor bodies, or regions thereof, of devices having potential barriers characterised by the materials being Group III-V materials, e.g. GaAs
H10D 64/62 - Electrodes ohmically coupled to a semiconductor
16.
GaN HEMT device for irradiation damage detection and detection and manufacturing method therefor
The present invention discloses a GaN HEMT device for irradiation damage detection which comprises a substrate layer, a gallium nitride layer, a barrier layer and a dielectric layer. A p-type gallium nitride layer is provided on the barrier layer. A drain and a source are respectively located at an inner side and an outer side of the p-type gallium nitride layer and provided on the gallium nitride layer. A Schottky metal layer is provided on the p-type gallium nitride layer. A first ohmic metal layer and a second ohmic metal layer are respectively located at an inner side and an outer side of the p-type gallium nitride layer and provided on the barrier layer. The second ohmic metal layer includes inner gear electrodes and outer gear electrodes, which are interdigital with each other.
G01R 31/00 - Arrangements for testing electric propertiesArrangements for locating electric faultsArrangements for electrical testing characterised by what is being tested not provided for elsewhere
G01R 31/26 - Testing of individual semiconductor devices
G01R 31/27 - Testing of devices without physical removal from the circuit of which they form part, e.g. compensating for effects due to surrounding elements
G01R 31/28 - Testing of electronic circuits, e.g. by signal tracer
G01R 31/30 - Marginal testing, e.g. by varying supply voltage
Jiangsu Jichuang Atomic Cluster Technology Research Institute Co., Ltd. (China)
Nanjing University (China)
Inventor
Song, Fengqi
Zhang, Minhao
Liu, Xueyu
Tang, Sichen
Chen, Ning
Abstract
A method for doping a two-dimensional material based on cluster ion implantation, including selecting a two-dimensional material sample to place same on a substrate; determining the selected implantation parameters by Monte Carlo particle tracing algorithm on the two-dimensional material sample; replacing the two-dimensional material sample, and placing a two-dimensional material thin film, wherein the thickness of the two-dimensional material thin film is ≤10 nm; selecting a determined implantation parameter to form a cluster beam and acting on a two-dimensional material thin film; changing the implantation parameters to form different cluster beams and acting on the two-dimensional material thin film; performing annealing on the two-dimensional material thin film implanted with cluster ions to repair the damage caused by implantation. The method is applicable to two-dimensional semiconductor materials by using ion clusters for implantation such that damage to the crystal lattice by the ion implantation is reduced.
H01J 37/317 - Electron-beam or ion-beam tubes for localised treatment of objects for changing properties of the objects or for applying thin layers thereon, e.g. ion implantation
H01J 37/24 - Circuit arrangements not adapted to a particular application of the tube and not otherwise provided for
18.
METHOD AND APPARATUS FOR TRAINING SIMULATED HARDWARE NEURAL NETWORK
A method and apparatus for training a simulated hardware neural network. The method comprises: inputting training information into a simulated hardware neural network, the simulated hardware neural network establishing a response to an input signal, and measuring an output result of the simulated hardware neural network; injecting a perturbation signal into a specific network node while the simulated hardware neural network runs, and measuring a response produced by the perturbation signal; and updating intrinsic parameters of the simulated hardware neural network on the basis of the results of the two measurements.
The present invention discloses a GaN HEMT transistor with impact energy release capability for use in aerospace irradiation environment and preparation method thereof. The transistor includes a substrate layer, a gallium nitride layer, a barrier layer, and a gate structure successively arranged from bottom to top. The gallium nitride layers on both sides of the barrier layer are respectively provided with a source electrode and a drain electrode on the top surface. The gate structure is located near the source electrode and includes a p-type gallium nitride layer, a dielectric layer, an Ohmic metal pillar, and a Schottky metal layer. The present invention solves the breakdown problem caused by the inability to release impact energy during the switching process by introducing an asymmetric multi-integrated gate structure.
H01L 29/778 - Field-effect transistors with two-dimensional charge carrier gas channel, e.g. HEMT
H01L 29/20 - Semiconductor bodies characterised by the materials of which they are formed including, apart from doping materials or other impurities, only AIIIBV compounds
A voltage-controlled three-terminal magnon transistor is provided, including a ferroelectric layer, a magnetic layer, a generation terminal, a control terminal, a detection terminal, and a bottom electrode. After a current is inputted into the generation terminal, a magnon is generated in the magnetic layer. The detection terminal is made of a heavy metal material, which can convert the magnon in the magnetic layer into a charge flow. When a voltage pulse applied between the control terminal and the bottom electrode exceeds a critical value, non-volatile polarization and non-volatile strain states of the ferroelectric layer change, which in turn affects a transmission capability of the magnon in the magnetic layer based on a magnetoelectric coupling effect between the ferroelectric layer and the magnetic layer. In addition, a voltage signal of the detection terminal exhibits a regular loop change behavior with a change of the voltage pulse.
The present invention provides a voltage-controlled three-terminal magnon transistor, comprising a ferroelectric layer, a magnetic layer, a generation terminal, a control terminal, a detection terminal, and a bottom electrode, wherein the generation terminal generates magnons in the magnetic layer when the current is introduced; the detection terminal is made of a heavy metal material, and can convert the magnons in the magnetic layer into a charge flow; and when a voltage pulse applied between the control terminal and the bottom electrode exceeds a critical value, the non-volatile electric polarization and the non-volatile strain state of the ferroelectric layer are changed, so that the transmission capability of the magnons in the magnetic layer is affected by the magnetoelectric coupling effect between the ferroelectric layer and the magnetic layer, and a voltage signal of the detection terminal shows a regular loop change behavior as the voltage pulse changes. Furthermore, also disclosed in the present invention are a control method and preparation method for the device. The three-terminal magnon transistor disclosed in the present invention can work in a wide temperature range including room temperature, has a high on-off ratio and is non-volatile.
Disclosed in the present invention is a deep learning-based method for assisting in surgical level selection in adolescent idiopathic scoliosis (AIS), comprising the following steps: collecting data according to a standard, and establishing a database; using LabelMe to label and preprocess collected image data; taking the labeled and preprocessed image as an input to train a network model, wherein the network model adopts a combination of two deep learning frameworks which are UNet and YOLOv8; using the trained network model to perform image segmentation of a spine X-ray anteroposterior film, and giving a category label to each segmentation area; and in light of prior knowledge, calculating the confidence for a surgery on the basis of the position and categories of levels given by the network model. The method can help a doctor quickly and accurately determine a surgical fusion level in AIS, and manual intervention is not needed in the whole process from input of X-ray images to confidence calculation.
A cell electrical activity imaging apparatus based on an electrochemically modulated ion lens, and a measurement method. The apparatus comprises: an electrochemical modulation module used for applying a modulation voltage of a fixed frequency to a cell; a laser adjustment module used for introducing monochromatic laser into interference scattering imaging and adjusting the intensity and spot size of the laser; an imaging detection module used for recording a change in the surface charge density of a cell membrane generated along with an electrical activity of the cell; and a signal input module connected to the imaging detection module and the electrochemical modulation module and used for inputting a modulation signal and controlling imaging acquisition. Electrochemical modulation is introduced into interference scattering imaging, so that under voltage modulation, by directly detecting a scattering field of the ion lens on the surface of the cell membrane, information on the electrical activity of the cell at the level of the whole cell and the level of a single ion channel can be obtained.
Provided in the present application are a processing method and processing apparatus for a smart contract on a blockchain. The processing method comprises: acquiring a first syntax tree corresponding to a source contract; identifying risk nodes from the first syntax tree, wherein the risk nodes relate to risk operations; and performing at least one of the following processings on the first syntax tree to obtain a second syntax tree: replacing a first risk node among the risk nodes with a first security node, wherein the first risk node relates to a first risk operation, the first security node relates to a first security operation, and the first security operation is used to replace the first risk operation; alternatively, adding a permission checking condition to a second risk node among the risk nodes, wherein the permission checking condition is used to determine the identity of a caller when a function indicated by the second risk node is called. The solution of the embodiments of the present application helps to improve the security of a smart contract.
Disclosed in the present invention is a method for simulating the transport of a reactive solute in groundwater in a three-dimensional fracture network, which method is used for simulating a reactive transport pattern of a solute in groundwater in a fracture medium. The method can take into consideration the detailed depiction of the transport process of a reactive solute in a fracture and the hydraulic connection between the fracture and surrounding rock, thereby affecting the spatial distribution of a water flow field and a chemical field in a fracture network; and a water flow field and chemical field coupling model in a three-dimensional fracture network is constructed to simulate the hydraulic connection between the fracture and the surrounding rock, so as to study the transport process of a reactive solute in groundwater in the fracture network. The method provided in the present invention comprises: taking into consideration the transport of a reactive solute in groundwater in a fracture and the hydraulic connection between the fracture and surrounding rock; constructing a model for the process of coupling a water flow field and a chemical field; and carrying out numerical simulation on the transport of the reactive solute in groundwater in a three-dimensional fracture network. The simulation technique provided in the present invention can provide a scientific and rational theoretical basis for the study of space-time distribution of reactive transport of a target solute in groundwater in a fracture network.
G06F 30/28 - Design optimisation, verification or simulation using fluid dynamics, e.g. using Navier-Stokes equations or computational fluid dynamics [CFD]
A nanocrystal photoresist-free photolithographic method based on an organophosphine ligand.By means of introducing an organic molecule containing a phosphorus group to serve as a photosensitive ligand to convert a nanocrystal into a photosensitive coating, direct patterning is realized. The solution solves the problem of effectively reducing the performance loss of the nanocrystal during the process of completing patterning, and has the following advantages: 1) high regiospecificity/stereospecificity; 2) a photosensitive interval being adjustable, and being suitable for photolithography using DUV, i-line and h-line light sources; 3) having high reaction sensitivity and requiring an extremely low exposure dose; and 4) being insensitive to the environment, being operable in an air atmosphere, involving mild reaction conditions and being easily operated. The process is expected to be applied to the commercialization of nanocrystals in the field of electroluminescent and photoluminescent quantum dot displays.
A compact rotary algae biofilm reactor includes an algae biofilm module and a light guide module. The algae biofilm module includes a plurality of rotary members and a reaction tank. In the rotary member, an algae biofilm growth carrier and a power transmission belt are wound on a driving shaft and a driven shaft. A top end of the rotary member is fixed on a fixing frame while a bottom end thereof is submerged in the reaction tank. The light guide module includes a rotatable lens holder. The rotatable lens holder is fixedly provided with a linear Fresnel lens on an upper end thereof and is provided with a light guide plate on a lower end thereof. One side of the linear Fresnel lens is provided with a step motor configured to control the linear Fresnel lens to rotate with an angle of sunlight.
A Cu+/Li+double-ion conductor and a high-power all-solid-state lithium battery, which belong to the technical field of solid-state lithium batteries. A Cu+/Li+ double-ion conductor is constructed, and on the basis of the double-ion conductor, a high-speed ion pathway connecting a positive electrode active material and a composite positive electrode electrolyte is constructed, thereby realizing rapid migration of ions at an interface, and greatly improving the rate capability of a battery.
A deep learning-based method for predicting the settleability of activated sludge includes: (1) collecting a plurality of activated sludge samples, acquiring raw data of images of the plurality of activated sludge samples, cleaning the raw data of the images, and standardizing data sizes of the images; (2) calculating a sludge volume index (SVI) for each of the plurality of activated sludge samples; (3) establishing, by using a ResNet50 deep neural network, a model for predicting the settleability of activated sludge; and (4) predicting the settleability of a target activated sludge using the model established in (3).
Jiangsu Jichuang Atomic Cluster Technology Research Institute Co., Ltd. (China)
Nanjing University (China)
Inventor
Song, Fengqi
Zhang, Minhao
Xie, Suyuan
Ji, Wei
Tan, Yuanzhi
Chen, Jun
Zhang, Kangkang
Liu, Bowen
Gu, Luwei
Abstract
An atomic-scale cluster storage and compute device is successively provided with a substrate and oxide layer, a gate electrode, and a gate dielectric layer from bottom to top; at least one conductive electrode is provided on the gate dielectric layer, and one nanoscale gap is provided on each conductive electrode; two sides of the nanoscale gap are a source electrode and a drain electrode, and a combined molecular system is provided in the nanoscale gap; the combined molecular system is a composite system of one or more functional atoms and a single molecule, which forms good contact with a source electrode and a drain electrode, and the combined molecular system has the feature of a single electric dipole and bistable state. A combined molecular system of a single molecule with several functional atoms is constructed; the combined molecular system has the feature of a single electric dipole and bistable state.
Disclosed in the present invention are a geographic position-based high-speed rail mobile communication 6G fully-decoupled network uplink transmission method and system. The method comprises: according to geographic positions of a train and each uplink base station, performing line-of-sight channel mapping, so as to serve as channel estimation to carry out a secondary combining joint reception processing of the uplink signals; designing a deep learning neural network, taking the mapped line-of-sight channel as an input, and outputting a multi-user joint precoding that meets constraint conditions; performing offline training on a network by using historical channel data of each position; in an actual deployment stage, inputting a line-of-sight channel corresponding to the train position, the network outputting a joint precoding at the corresponding position, so as to achieve transmission without feedback. Compared with a traditional precoding design solution, the present invention solves the problem in a high-speed rail scenario of untimely channel feedback and large resource overhead due to high-speed movement, improves the frequency effect of wireless communication in a high-speed rail scenario, and provides an effective uplink transmission method for future high-speed rail mobile communications.
A method for reducing mDON concentration in wastewater, including a) acquiring a kinetics associated with production and consumption of a mDON of an activated sludge system, and importing a kinetic expression of the mDON into a conventional activated sludge model No. 1 (ASM1) to build a kinetic equation for the mDON; b) inputting component variables, parameter variables, model matrices, process rate equation and operating parameters of a predictive model into a simulation software to build an ASM-mDON model; c) inputting initial values of the component variables and the parameter variables into the simulation software for model initialization; d) acquiring initial mDON kinetic and sensitivity analysis results, selecting corresponding parameters, calibrating kinetic and stoichiometric parameters of the ASM-mDON model using a parameter estimation function of the simulation software; and e) replacing the initial values of the ASM-mDON model with optimal values obtained in d).
The present invention belongs to the technical field of nanobodies, and specifically relates to an anti-ouabain nanobody and the use thereof. The amino acid sequence of the anti-ouabain nanobody is as shown in SEQ ID NO. 1. The nucleotide sequence thereof is as shown in SEQ ID NO. 2. The antibody has a good affinity to ouabain, can neutralize and antagonize the pharmacological activity of ouabain, and can be used to detect the content of ouabain in a solution in combination with an ELISA method. The present invention provides a method for constructing an ouabain antibody having a light weight, a high thermostability and a high detection sensitivity, and provides a research tool for deeply exploring the new biological functions of endogenous ouabain.
The present invention relates to a double-acid catalyst and a method for preparing furfural by catalyzing hemicellulose or xylose. The double-acid catalyst comprises choline chloride, a Bronsted acid, and a Lewis acid at a molar ratio of 1:1:1-4, and is in a deep eutectic state. The method comprises the following steps: adding into a reaction kettle a hemicellulose or xylose raw material, and the double-acid catalyst as a water phase, then adding an oil phase extraction agent, and carrying out catalytic dehydration and hydrolysis reactions in the reaction kettle to generate furfural, wherein the oil phase extraction agent continuously extracts the furfural from the water phase in the reaction process until the reaction is finished. According to the present invention, the choline chloride is combined with the Lewis acid and the Bronsted acid to form a deep eutectic solvent as the double-acid catalyst, and the deep eutectic solvent is used in the process of preparing furfural by catalyzing hemicellulose or xylose, thereby reducing the activation energy required by the reaction, and increasing the yield of the furfural. In addition, the water phase and the catalyst in the preparation process can both be recycled, thereby reducing the energy consumption and the production cost.
B01J 31/34 - Catalysts comprising hydrides, coordination complexes or organic compounds containing in addition, inorganic metal compounds not provided for in groups of chromium, molybdenum or tungsten
The present invention belongs to the technical field of wastewater treatment and more specifically relates to a method for accurately controlling dissolved oxygen of an aerobic wastewater treatment system. The system integrates the functions of online monitoring and dissolved oxygen control of system parameters of a wastewater treatment plant, can acquire data of the dissolved oxygen concentration, openings of air valves, air quantity of a fan, influent quality and quantity of the wastewater treatment system in real time, automatically calculates ideal values of the air quantity of the fan and the openings of the air valves according to a target value of the dissolved oxygen concentration by a server, screens an optimal adjusting mode on the basis of a certain condition, and finally sends an instruction to the fan or the air valves to realize the accurate control of dissolved oxygen of the wastewater treatment system.
A method for producing an electrochemiluminescence nanoprobe according to an embodiment includes: a hot exciton nanoparticle synthesis step of polymerizing a hot exciton organic luminescent molecule and a copolymer molecule to synthesize hot exciton nanoparticles; and a hot exciton nanoparticle modification step of modifying the obtained hot exciton nanoparticles with an oligonucleotide chain modified with a quencher molecule to obtain modified hot exciton nanoparticles.
C09K 11/07 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials having chemically-interreactive components, e.g. reactive chemiluminescent compositions
C08F 8/34 - Introducing sulfur atoms or sulfur-containing groups
C12Q 1/34 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase
An alternating electric field-driven gallium nitride (GaN)-based nano-light-emitting diode (nanoLED) structure with an electric field enhancement effect is provided. The GaN-based nanoLED structure forms a nanopillar structure that runs through an indium tin oxide (ITO) layer, a p-type GaN layer, a multiple quantum well (MQW) active layer and an n-type GaN layer and reaches a GaN buffer layer; and the nanopillar structure has a cross-sectional area that is smallest at the MQW active layer and gradually increases towards two ends of a nanopillar, forming a pillar structure with a thin middle and two thick ends. The shape of the GaN-based nanopillar improves the electric field strength within the QW layer in the alternating electric field environment and increases the current density in the QW region of the nanopillar structure under current driving, forming strong electric field gain and current gain, thereby improving the luminous efficiency of the device.
H01L 33/08 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a plurality of light emitting regions, e.g. laterally discontinuous light emitting layer or photoluminescent region integrated within the semiconductor body
H01L 33/00 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof
H01L 33/02 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies
H01L 33/06 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a quantum effect structure or superlattice, e.g. tunnel junction within the light emitting region, e.g. quantum confinement structure or tunnel barrier
H01L 33/12 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a stress relaxation structure, e.g. buffer layer
H01L 33/24 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a particular shape, e.g. curved or truncated substrate of the light emitting region, e.g. non-planar junction
H01L 33/32 - Materials of the light emitting region containing only elements of group III and group V of the periodic system containing nitrogen
The present invention relates to the field of material preparation. Disclosed are a poly(carbazole phosphonic acid) material and a preparation method therefor and a use thereof. The poly(carbazole phosphonic acid) material provided by the present invention has better stability, and the good film-forming property of the said material and the interaction between macromolecular chains can effectively solve the problems of poor compactness, easy diffusion and the like of traditional carbazole phosphonic acid small molecules, thereby producing a stable photoelectric device based on poly(carbazole phosphonic acid). The synthesis method for poly(carbazole phosphonic acid) is simple and rapid and involves mild reaction conditions. An obtained poly(carbazole phosphonic acid) material is dissolved in methylbenzene, chlorobenzene, chloroform, dichloromethane, methanol, ethanol, isopropanol and other single or mixed solvents, and is processed into thin films by means of processes such as spin coating, blade coating, slit coating, dip coating, spraying, and then a photoelectric device based on the poly(carbazole phosphonic acid) material is prepared. The present application has important scientific significance and an extremely high industrial value.
H10K 30/20 - Organic devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation comprising organic-organic junctions, e.g. donor-acceptor junctions
40.
SYNTHESIS METHOD FOR LAYERED BIMETAL-BASED NANO LANTHANUM MATERIAL THAT SYNCHRONOUSLY LOCKS PHOSPHORUS, REMOVES ALGAE AND REDUCES TURBIDITY, AND USE THEREOF
33 thin film thicknesses; in addition, the solution can greatly improve the flexibility in design, compactness, mechanical stability, temperature stability and power tolerance of devices.
A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
C07C 309/81 - Halides of sulfonic acids having halosulfonyl groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
The present invention discloses an in-situ testing system for semiconductor device in aerospace irradiation environment. The present invention includes a static testing unit, a static testing channel, a dynamic testing unit, a dynamic testing channel, and a channel switching control unit; the static testing unit is connected to the device under test through the static testing channel, and is used to output static testing signals and display the static testing data of the device under test; the dynamic testing unit is connected to the device under test through the dynamic testing channel, and is used to output dynamic testing signals and display the dynamic testing data of the device under test; the channel switching control unit is connected to the static testing channel and the dynamic testing channel, respectively. This invention can achieve static, dynamic, and degradation testing of third-generation semiconductor device in aerospace irradiation environment.
Method for confirming ownership of digital assets based on hash algorithm and method for tracing to a source of digital assets based on hash algorithm are provided. Entities involved in confirming the ownership of digital assets include an original user, a CA authentication center and a digital asset authentication center. The process of confirming the ownership includes generating a one-time CA certificate by the original user, authenticating the digital assets by the digital asset authorization center and the original user, generating an ownership confirming document by the original user, creating a quantum digital signature by a three-party, and the like. The method for tracing includes generating subsidiary documents in real time, constructing a unique identity for a digital asset at an accessing moment, traceability analysis, and so on.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
An ocean current detection device and method based on double-helix and double-core vibration fiber-optic cable, comprises a double-core fiber-optic cable and a φ-OTDR system; the double-core fiber-optic cable comprises a first and a second optical fiber core, provided symmetrically in the double helix structure. The terminate ends of the first and the second optical fiber core are connected, and the start end of the first or the second optical fiber core is connected with the φ-OTDR system. When measuring the ocean current characteristics in the target sea area, the double-core fiber-optic cable is provided underwater to generate vortex-induced vibration. The φ-OTDR system is provided for emitting laser towards the cable, receiving returned double-core vibration signals, extracting vibration characteristics from the double-core vibration signals to determine ocean current characteristics, including ocean current flow velocity and direction, to improve the detection accuracy.
G01P 5/26 - Measuring speed of fluids, e.g. of air streamMeasuring speed of bodies relative to fluids, e.g. of ship, of aircraft by measuring the direct influence of the streaming fluid on the properties of a detecting optical wave
G01P 13/02 - Indicating direction only, e.g. by weather vane
46.
MONITORING SYSTEM AND METHOD FOR BROKEN WIRES IN PCCP BASED ON DISTRIBUTED OPTICAL FIBER SENSING
A monitoring system and method for broken wires in PCCP based on distributed optical fiber sensing relates to the technical field of optical fiber sensing. The monitoring system for broken wires in PCCP comprises a Sagnac interferometer, a Φ-OTDR system, a dual loopback system and a signal processing system. The Sagnac interferometer comprises a first laser, a first optical coupler, a first delay optical fiber, a Faraday rotating mirror and a first photodetector. The Φ-OTDR system comprises a second laser, a second optical coupler, an acousto-optic modulator, a circulator, a third optical coupler and a second photodetector. The dual loopback system comprises a wavelength division multiplexer and a second delay optical fiber. The invention solves the problems of low positioning accuracy, limited frequency measurement range, detection dead zone and high computing pressure in monitoring broken wires in PCCP.
CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE (China)
HUAZHONG AGRICULTURAL UNIVERSITY (China)
Inventor
Dong, Xianchi
Liu, Wen
Ding, Jianping
Shi, Yu
Xu, Shutong
Xu, Jianbo
Abstract
Provided are a protein containing an amino acid sequence capable of binding to a peptide fragment of a substrate GPRP, a fibrinogen-like protein 1 (FGL1) containing the amino acid sequence, and a fibrinogen domain (FD) of the FGL1, wherein a single FD protein also has a function the same as or similar to that of the FGL1. The FGL1 and FD, which have different action mechanisms from existing drugs, can inhibit fibrin assembly in the process of thrombogenesis by means of competing for fibrin substrate binding pockets. The FGL1 and FD can have a stronger affinity to the substrate by means of mutation, thereby effectively enhancing a usage effect of drugs for treating thrombus.
Disclosed in the present invention are a method and device for imaging and calculation, and a computer readable medium. The method comprises: extracting a field of view image of a target field of view, and searching the field of view for a specific target; according to the attribute of the specific target, determining a calculation kernel corresponding to the specific target, wherein the calculation kernel is expressed by a weight value matrix; performing convolution calculation in an imaging region by using the calculation kernel; and performing searching and matching on the field of view image to obtain a feature map corresponding to the specific target.
The present invention provides a method and a system for predicting carbon emission from agricultural land, relates to the technical field of carbon emission prediction, comprising: Using the CLUMondo model to predict the agricultural land area of the target area at a future time; Determining methane emissions from paddy fields at a future time based on the area of rice planted in the agricultural land area; Determining the direct and indirect nitrous oxide emissions at a future time based on the nitrogen input to the agricultural land area; Determining methane emissions from animal enteric fermentation, methane emissions from animal manure management, and nitrous oxide emissions from animal manure management based on the number of animals in the agricultural land area.
G06Q 10/04 - Forecasting or optimisation specially adapted for administrative or management purposes, e.g. linear programming or "cutting stock problem"
A metal-resin composite, a surface treatment method, and a substrate of a printed circuit board (PCB) for high-frequency and high-speed signal transmission comprise a surface-treated metal, and the surface-treated metal includes a nano-scale pore array that is used for filling of a resin and vertically extends from a surface to an interior of a metal, where nano-scale pillars are provided to extend from bottoms to openings of nano-scale pores of the nano-scale pore array. The pillar-in-pore structure makes a resin entering a nano-scale pore have an ultra-high anchoring effect on a resin body outside the nano-scale pore. Therefore, on the premise of not using an additive such as a T liquid or a coupling agent, the present disclosure greatly improves a tensile bonding strength at an interface between a resin body and a metal substrate, and also eliminates a decline in an interfacial bonding strength of a composite.
B29C 45/14 - Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mouldApparatus therefor incorporating preformed parts or layers, e.g. injection moulding around inserts or for coating articles
An arrayed nanopore micro-current signal parallel measurement apparatus (2), comprising a gating apparatus (A) of a nanopore multi-path measurement unit, a multi-path nanopore current signal amplifying and signal processing apparatus (C), a multi-path nanopore current signal acquisition apparatus (B), an FPGA control chip (12), and a single-chip microcomputer (14). The arrayed nanopore micro-current signal parallel measurement apparatus can achieve high-bandwidth amplification and measurement of an arrayed nanopore micro-current signal, and ensures a signal sampling bandwidth by means of the high sampling rates of a bandwidth compensation circuit and an analog-to-digital converter. The gating apparatus (A) of the nanopore multi-path measurement unit can acquire the nanopore micro-current signal of a specified channel in a directional or polling manner, thereby achieving grouping control and polling sampling of a multi-path nanopore detection system. The arrayed nanopore micro-current signal parallel measurement apparatus not only can be applied to acquisition and reading of micro-current signals in nanopore protein molecule sequencing, but also can be used for detection of other micro-current measurement systems such as ion channel drug screening and single-particle collision electrochemical detection.
Disclosed are a scenario test method and apparatus of a driving control system, a medium, and a device. According to the method, a state transition diagram is input, and then the test coverage of each state transition in the state transition diagram is gradually implemented on the basis of the state transition diagram and by means of a cyclic iterative variation of a scenario sample. When the cyclic iterative variation is performed, a simulation output of the scenario sample is used as a reference, so that an iterative process can quickly converge the purpose of corresponding state transitions thereof completing coverage testing. The present invention can visually test the processing capability and level of the driving control system for a driving environment, and has high test efficiency.
A nano porin-based high-throughput detection device, comprising a biochip (1), bilayer membranes (3), a micro-well group (12), micro-wells (7), and a pool body structure (13). One or more micro-well groups (12) are arranged on the biochip (1); the micro-well group (12) comprises a plurality of micro-wells (7); the whole pool body structure (13) is of a cylindrical structure with an upper opening and a lower opening; the pool body structure (13) is integrally tiled on the upper surface of the biochip (1) and is tightly connected to the biochip (1); an inner cavity of the pool body structure (13) is separately communicated with the plurality of micro-wells (7); a polar medium (4) containing porins (18) is injected into the inner cavity of the pool body structure (13); a micro-well opening (8) of each micro-well (7) is provided with a bilayer membrane (3); the porins (18) are inserted onto the bilayer membranes (3). According to the nano porin-based high-throughput detection device, the membrane forming throughput can be improved, the types of membranes formed at the same timer are increased, the membrane forming efficiency is improved, and various porins (18) can be accommodated.
G01N 27/26 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variablesInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by using electrolysis or electrophoresis
54.
LAND USE STRUCTURE PATTERN LAYER MINING METHOD BASED ON GRAPH CONVOLUTIONAL NETWORK
The present invention relates to a land use structure pattern layer mining method based on a graph convolutional network, which comprises the following steps: obtaining land use data; constructing a graph structure; generating a label input model; training the label input model by means of a graph convolutional network model, and generating a graph embedding; utilizing a spatially constrained multivariate clustering method to perform separation on the graph embedding, and obtaining a layered partition structure from partitions to each level of sub-partitions; separately using land use type frequency characteristics for each year of land use data to construct region-level primitives for each region; and representing temporo-spatial changes to the land use structure of a region according to the changes to region-level primitives of said region in different years. The influence of multiple orders of neighboring areas are taken into account when the primitives are constructed, partitioning can be carried out according to differences in land use spatial structures, and layered land use structure patterns and dynamic characteristics thereof can be effectively mined.
NANJING STAR HIDDEN TECHNOLOGY DEVELOPMENT CO., LTD. (China)
Inventor
Lai, Yun
Wang, Cong
Chu, Hongchen
Mou, Wenri
Abstract
The present invention relates to a wave-absorbing structure and a device. The wave-absorbing structure comprises a metasurface structure and at least one wave-absorbing material provided on the metasurface structure; the metasurface structure is provided with a plurality of metasurface units, each metasurface unit has a corresponding regulation and control parameter, and the regulation and control parameter of each metasurface unit is configured to: convert, on the metasurface structure, an incident electromagnetic wave into at least one pair of surface waves which can be absorbed by the at least one wave-absorbing material; and the at least one pair of surface waves propagate in opposite directions along the metasurface structure and overlap at the position of the at least one wave-absorbing material. According to the wave-absorbing structure, a metasurface structure is use to replace a resonant cavity, an optical splitter and a phase shifter in a conventional laboratory structure, reducing the complexity of an electromagnetic wave-absorbing system, and successfully bringing a coherent wave-absorbing scenario into a general electromagnetic environment.
Method for confirming ownership of digital assets based on hash algorithm and method for tracing to a source of digital assets based on hash algorithm are provided. Entities involved in confirming the ownership of digital assets include an original user, a CA authentication center and a digital asset authentication center. The process of confirming the ownership includes generating a one-time CA certificate by the original user, authenticating the digital assets by the digital asset authorization center and the original user, generating an ownership confirming document by the original user, creating a quantum digital signature by a three-party, and the like. The method for tracing includes generating subsidiary documents in real time, constructing a unique identity for a digital asset at an accessing moment, traceability analysis, and so on.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
H04L 9/06 - Arrangements for secret or secure communicationsNetwork security protocols the encryption apparatus using shift registers or memories for blockwise coding, e.g. D.E.S. systems
57.
TEMPERATURE MEASUREMENT METHOD AND APPARATUS BASED ON PASSIVE RFID TAG
A temperature measurement method based on a passive RFID tag. The method comprises: acquiring a circuit temperature feature of a tag multiple times, and establishing a tag temperature-feature correspondence; and estimating, by using the tag temperature-feature correspondence and the current circuit temperature feature of the tag, the temperature of an environment where the tag is located, wherein the circuit temperature feature of the tag is the persistence time within which a passive RFID tag can operate normally during a discharging process after the tag is fully charged. By means of the method, a robust and accurate temperature measurement is achieved, and a tag can be directly deployed on an existing commercial RFID device without modifying the hardware of the tag and a reader.
G01K 11/00 - Measuring temperature based on physical or chemical changes not covered by group , , , or
G06K 19/07 - Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards with integrated circuit chips
58.
IMAGING SYSTEM, PREPARATION METHOD, AND IMAGE CAPTURING APPARATUS
The present invention relates to an imaging system, a preparation method, and an image capturing apparatus. The imaging system successively comprises, from an object side to an image side along an optical axis: a light source, configured to provide light irradiated to a sample; an imaging lens group, configured to receive light transmitted by the sample to image the sample at least once; and a phase modulation unit, configured to modulate light transmitted by the imaging lens group to form an expected sample image on an imaging surface of the imaging system. A plane where the phase modulation unit is located and a plane where the light source is located are a pair of conjugate planes; no lens or lens group for Fourier transform is introduced into at least an optical path between the plane where the phase modulation unit is located and the imaging surface of the imaging system. According to the imaging system, more diverse imaging effects can be achieved without changing an original microscopic imaging optical path basically, the resolution reduction can be avoided, and the imaging quality can be improved.
Disclosed in the present application are an AC current sensor and a wireless charging chip. The AC current sensor includes an integrator circuit, a differentiator circuit, and a calibration circuit. The integrator circuit is configured to perform integration on a voltage on which filter processing is performed across an inductor in a TX coil. The differentiator circuit is configured to perform differentiation on a voltage on which filter processing is performed across a capacitor in the TX coil. The calibration circuit is configured to sample and compare output signals of the integrator circuit and the differentiator circuit, and adjust output results of the integrator circuit and the differentiator circuit until the output results are the same. In this case, the output result of the differentiator circuit may be used to calculation for a current flowing through the TX coil.
A method of characterizing an analyte or the interaction between the analyte and an agent in a nanopore system, wherein the nanopore system comprises a protein nanopore disposed in a membrane that separates a first conductive liquid medium from a second conductive liquid medium, wherein the protein nanopore is MspA, MspA homolog or variant thereof, wherein the analyte has an conformation and the analyte with the conformation can be accommodated in the vestibule of the MspA, the MspA homolog or the variant thereof but cannot translocate through the MspA, the MspA homolog or the variant thereof, the method comprising: i) applying an electrical potential difference between the first conductive liquid medium and the second conductive liquid medium to drive the analyte into the nanopore, and optionally contacting the agent with the analyte; ii) measuring an ionic current through the protein nanopore to provide a tested current pattern that contains at least ionic current measured during the analyte is in the vestibule of the MspA, the MspA homolog or the variant thereof; iii) associating the tested current pattern with at least one characteristic of the analyte or the interaction between the analyte and an agent.
A conjugate may have formula (1), i.e., M-[(L1)a-(L2)b-(D)c] (1), wherein M is a biological macromolecule having a nucleophilic functional group, M is linked to L1 with the nucleophilic functional of M, D is a functional molecule, L2 is a linker, and L1 is a compound of formula 1
A conjugate may have formula (1), i.e., M-[(L1)a-(L2)b-(D)c] (1), wherein M is a biological macromolecule having a nucleophilic functional group, M is linked to L1 with the nucleophilic functional of M, D is a functional molecule, L2 is a linker, and L1 is a compound of formula 1
A conjugate may have formula (1), i.e., M-[(L1)a-(L2)b-(D)c] (1), wherein M is a biological macromolecule having a nucleophilic functional group, M is linked to L1 with the nucleophilic functional of M, D is a functional molecule, L2 is a linker, and L1 is a compound of formula 1
wherein R is —F or —OH, and L2 is linked to R1, R3 or R2, a is an integer of 1 to 10, b, c is each independently an integer of 0 to 10, provided that b and c are not simultaneously 0. R1, R2, and R3, may independently be H, optionally substituted alkyl, or optionally substituted aryl, and R1, may be H or isotope thereof Δ C may link R1 and a C linking R2 form a ring.
A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
NANJING STAR HIDDEN TECHNOLOGY DEVELOPMENT CO., LTD. (China)
Inventor
Chu, Hongchen
Lai, Yun
Xiong, Xiang
Peng, Ruwen
Wang, Mu
Abstract
The present disclosure relates to a transmission structure and a preparation method thereof. The transmission structure includes a plurality of first transmission units and a plurality of second transmission units, and difference between a first transmission phase of a transmitted electromagnetic wave of the first transmission unit and a second transmission phase of a transmitted electromagnetic wave of the second transmission unit is the same or similar within a preset frequency range. The plurality of first and second transmission units are arranged randomly on a surface. The first transmission unit has a first matrix, a first medium block is disposed inside the first matrix, and a thickness of the first matrix between the first medium block and an electromagnetic wave incident surface of the first transmission unit is a non-zero first thickness. The second transmission unit has a second matrix, a second medium block is disposed inside the second matrix, a thickness of the second matrix between the second medium block and an electromagnetic wave incident surface of the second transmission unit is a non-zero second thickness, and the first and second thicknesses are configured to enable the first and second transmission units to have a large phase difference of reflected electromagnetic waves in a wide frequency range.
Disclosed in the present invention are a biological wastewater treatment process reconstruction method and system based on machine learning. The method comprises: collecting influent and effluent water basic quality, ecological risk and process information data in a biological wastewater treatment procedure, and performing data preprocessing; performing feature extraction on biological wastewater treatment processes and performing multi-unit representation; constructing effluent water basic quality prediction models and effluent water ecological risk prediction models of different biological treatment multi-unit combined processes, and inspecting whether same are up to standard; simulating and reconstructing different biological wastewater treatment short-range unit combined processes, and inspecting whether the effluent water quality is up to standard in scenarios with different influent water qualities; and assessing the ecological risk of reconstructed biological treatment short-range unit combined processes, the effluent water quality of which is up to standard, and determining an optimal biological wastewater treatment process. By means of the present invention, a new biological treatment process that meets the requirements of the effluent water basic quality being up to standard and the biological risk being the lowest can be determined for scenarios with different influent water qualities, thereby removing the selection limitation of existing biological treatment process methods.
An isolated nucleic acid, a plasmid or viral vector thereof and a pharmaceutical composition thereof, and a method for treating a disease. The nucleic acid and the vector comprise at least one RNA fragment capable of inhibiting gene expression and/or a targeting tag having a targeting function, can be delivered into a host body, are enriched in an organ tissue of a host, and are self-assembled to form and secrete an exosome and target a target tissue, thereby treating the disease.
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
A retinomorphic sensor array and a convolution method are used for image processing therefor, wherein the optoelectronic sensor has a vertically stacked heterostructure provided with a bottom electrode, a dielectric layer, a channel layer, a source electrode and a drain electrode on a base, the source and drain electrode are mutually opposite and are arranged at two ends of the channel layer, the bottom electrode, the source and drain electrode are made of a material used by a flexible electrode, an inert metal or a semimetal, the dielectric layer is made of an insulating material, the channel layer is made of a bipolar material, and the base comprises a substrate and an insulating material layer generated on a surface of the substrate.
H01L 31/113 - Devices sensitive to infrared, visible or ultraviolet radiation characterised by field-effect operation, e.g. junction field-effect photo- transistor being of the conductor-insulator- semiconductor type, e.g. metal- insulator-semiconductor field-effect transistor
Provided are an imaging method and apparatus, and a medium. The method includes: for a target field of view, performing photographing and quantification at a first resolution, to obtain a first image that has a first bit width; for the target field of view, performing photographing and differential processing at a second resolution, to obtain a second image that has a second bit width, wherein the differential processing includes: for a pixel point obtained by photographing at the second resolution, quantifying the difference between the pixel point and a neighboring pixel point of the pixel point, to obtain a quantified difference a value of a corresponding pixel point in the second image; and fusing the first image with the second image, to obtain a third image, wherein the first resolution is lower than the second resolution, and the first bit width is higher than the second bit width.
Embodiments of the present disclosure provide a detection device for laser spot welding micro-weld spot quality based on laser ultrasound. The device includes: a nanosecond pulsed laser configured to emit a laser; the polarizing beam splitter configured to perform a laser beam splitting, wherein a laser beam after performing the laser beam splitting by the polarizing beam splitter enter an energy detector and a beam splitter mirror, respectively; the beam splitter mirror configured to perform the laser beam splitting on the laser entering the beam splitter mirror, wherein a laser beam after performing the laser beam splitting enter a photodetector and a light reflecting mirror, respectively; an aperture configured for the laser beam passing through the light reflecting mirror, the laser passing through a scanning galvanometer to reach a multi-axis displacement platform; the multi-axis displacement platform configured to place and/or move a sample.
B23K 31/12 - Processes relevant to this subclass, specially adapted for particular articles or purposes, but not covered by any single one of main groups relating to investigating the properties, e.g. the weldability, of materials
68.
METHOD FOR CORRECTING DOT PRODUCT ERROR OF VARIABLE RESISTOR ARRAY
Disclosed is a method for correcting a dot product error of a variable resistor array. The method includes: (1) initializing and writing a target conductance matrix into the variable resistor array; (2) calculating an effective conductance matrix of the variable resistor array; and (3) comparing the effective conductance matrix obtained in step (2) with the target conductance matrix, finishing executing the method in a case that a convergence condition is satisfied, and otherwise, continuing to execute steps as follows: multiplying a difference matrix by an adjustment coefficient η, such that an error conductance matrix is obtained; adjusting a conductance matrix Gwrite of actual variable resistors to Gwrite=G′write− Gerror, where Gerror is the error conductance matrix, G′write is a conductance matrix actually written into variable resistors last time; and executing steps (2) and (3) repeatedly after adjustment until a stop condition in step (3) is satisfied.
G06F 7/544 - Methods or arrangements for performing computations using exclusively denominational number representation, e.g. using binary, ternary, decimal representation using non-contact-making devices, e.g. tube, solid state deviceMethods or arrangements for performing computations using exclusively denominational number representation, e.g. using binary, ternary, decimal representation using unspecified devices for evaluating functions by calculation
The present invention relates to the field of solid-phase extraction, and particularly to a solid-phase extraction material, and a preparation method and use thereof. The preparation method includes prepolymerizing the monomers N-vinylpyrrolidone and divinylbenzene in the presence of a chain transfer agent, adding prepolymer dropwise to an emulsion of monodispersed seed microspheres, swelling, and reacting to prepare white spheres; and functionalizing the white spheres, to obtain the solid-phase extraction material. The solid-phase extraction material prepared by the reaction has good spherical morphology, large specific surface area, and high ion exchange capacity. The prepared solid-phase extraction material functions in the separation and enrichment of PPCPs by means of a variety of forces with a high extraction rate. The extraction rate is basically maintained between 85% and 105%, and acidic, alkaline, neutral and amphoteric substances is capable of being selectively separated.
A bioorthogonal cycloaddition reaction is provided, as well as the use in assembly of TAC-type molecules and use in preparation of bioconjugates. A method of performing a coupling reaction, comprising providing a first structure comprising a dione group or derivative thereof and a second structure capable of providing anionic furan-2-olate or derivative thereof.
C07D 307/77 - Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
72.
Silicon carbide-based lateral PN junction extreme ultraviolet detector based on selective-area ion implantation, and preparation method thereof
The present invention discloses a novel silicon carbide-based lateral PN junction extreme ultraviolet detector with enhanced detection performance based on selective-area ion implantation, including an N-type ohmic contact lower electrode, an N-type substrate and a lightly-doped epitaxial layer which are connected sequentially from bottom to top, where the lightly-doped epitaxial layer is an N-type lightly-doped epitaxial layer or a P-type lightly-doped epitaxial layer; in a case that the lightly-doped epitaxial layer is an N-type or P-type lightly-doped epitaxial layer, a P-type or N-type well region is formed on the surface of the N-type or P-type lightly-doped epitaxial layer through the selective-area ion implantation, a P-type or N-type ohmic contact upper electrode is arranged on the P-type or N-type well region, and the P-type or N-type ohmic contact upper electrode is provided with a metal conductive electrode along its periphery.
H01L 31/103 - Devices sensitive to infrared, visible or ultraviolet radiation characterised by only one potential barrier or surface barrier the potential barrier being of the PN homojunction type
The present disclosure provides methods, compositions, and kits for high-throughput single-cell analysis, such as nucleic acid analysis. In some embodiments, methods, compositions and kits for indexing a plurality of samples are provided. In some embodiments, methods, compositions and kits for high-throughput single-cell nucleic acid analysis, such as RNA sequencing are provided. The present disclosure allows fast, efficient and convenient cell labeling and sample pooling without being limited by cell types.
C12Q 1/6881 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
74.
METHOD FOR RECYCLING SILVER FROM WASTE IC CHIPS USING SOLUBLE STARCH
A method for recycling silver from a waste IC chip include: heating to disassemble an IC chip, and crushing the IC chip into powders; adding the powders to a nitric acid solution, heating, centrifuging and collecting a first filtrate; adding soluble starch to the first filtrate, where a mass concentration ratio of the soluble starch to Fe in the first filtrate is 5.20-7.30; heating a resulting mixture to 130-175° C. for a first hydrothermal reaction, separating a precipitate from the first hydrothermal reaction and collecting a second filtrate; heating the second filtrate to 160-230° C. for a second hydrothermal reaction, separating a solid from the second hydrothermal reaction and collecting a third filtrate; drying, grinding, and sieving the solid to obtain silver powders; and adding alkali to the third filtrate to form a precipitate of Cu, and separating the precipitate to yield copper hydroxide.
B22F 9/04 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using physical processes starting from solid material, e.g. by crushing, grinding or milling
B22F 9/24 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using chemical processes with reduction of metal compounds starting from liquid metal compounds, e.g. solutions
A display module, a backlight module and a display apparatus. The display module comprises a main waveguide (102), an external light source (101) enters a waveguide layer by means of the main waveguide (102), and multiple paths of secondary waveguides (111-119) are fanned out by means of a light beam coupling unit (103), each path of secondary waveguide (111-119) corresponding to one row of pixels; and a high-collimation light beam is output after light output from pixel waveguides (121-130) pass through a collimating lens (150) and a light beam conversion structure (160). The backlight module comprises a pixel display module and two layers of electrowetting prism arrays (4, 5), and the collimated decoherence light passes through the two layers of electrowetting prism arrays (4, 5) to achieve angular deflection in the XY direction. The display apparatus comprises a backlight module, and upper and lower polarizers (6, 10), upper and lower TFT glass substrates (7, 9), a liquid crystal layer (8), a color filter layer (11), and a display phase plate (12) which are arranged at the light exiting end of the backlight module. The light passes through the display phase plate (12) to form left and right eye fields of view, thus generating a real 3D effect. By means of voltage control, the present invention not only improves the resolution and observation field of view of 3D display, but also achieves free switching between a 2D observation mode and a 3D observation mode.
G02B 30/33 - Optical systems or apparatus for producing three-dimensional [3D] effects, e.g. stereoscopic images by providing first and second parallax images to an observer’s left and right eyes of the autostereoscopic type involving directional light or back-light sources
A light guide plate (100), a backlight module, and a display device. The light guide plate (100) comprises: a light incident surface (110); a light emergent surface (120) connected to the light incident surface (110); and a bottom surface (130) arranged opposite the light emergent surface (120). The bottom surface (130) comprises a first region (S region) and a second region (P region) which are sequentially arranged in a direction away from the light incident surface (110). The distance from any point in the first region (S region) to the light incident surface (110) is less than the distance from any point in the second region (P region) to the light incident surface (110). A plurality of first light guide points (140) and a plurality of second light guide points (150) are provided in the first region (S region). A plurality of first light guide points (140) are provided in the second region (P region). The first light guide points (140) have first reflective surfaces (141) facing the light incident surface (110). Included angles between the first reflective surfaces (141) and the bottom surface (130) are first included angles (α1). The second light guide points (150) have second reflective surfaces (151) facing the light incident surface (110). Included angles between the second reflective surfaces (151) and the bottom surface (130) are second included angles (α2). The first included angles (α1) and the second included angles (α2) are less than or equal to 5°. Furthermore, the first included angles (α1) are smaller than the second included angles (α2). The light guide plate (100) can achieve narrow viewing angle display without affecting light-emitting uniformity.
HAIAN INSTITUTE OF HIGH-TECH RESEARCH, NANJING UNIVERSITY (China)
Inventor
Tang, Shaochun
Jia, Suyue
Yang, Peng
Lu, Hongbin
Wu, Yang
Huang, Ye
Abstract
22 nano-scale phase change material is prepared by means of a sol-gel method in combination with a microemulsion method under alkaline conditions. The material prepared in the present application has a particle size of about 500 nm, a phase change temperature of 27.7ºC, a phase change latent heat of 159.74 J/g, and a thermal decomposition temperature that is 50ºC higher than the thermal decomposition temperature of n-octadecane.
Provided in the present disclosure are a memory unit, a storage method, a memory array, a memory and a manufacturing method therefor. The storage method uses at least one three-dimensional dynamic random access memory unit and comprises: applying a suitable voltage to a selected gate layer used for storing information, so that a charge coupling layer controlled by the gate layer carries out dynamic random storage of information, first and second doped type material layers writing and resetting involved information in collaboration with each other; applying a suitable voltage to a selected gate layer for reading, so as to alter the on-off capability of a signal reading layer controlled by the gate layer, thereby reading out a voltage or current related to the information as third and fourth doped type material layers respectively serve as a source and a drain of the signal reading layer; and performing information storage in such a way of stacking layer by layer in the vertical direction or partition by partition in the horizontal direction the information stored in a plurality of gate layers. The method provided by the present disclosure can separate writing paths from reading paths, and has the characteristics such as high storage density, high speed and low power consumption.
The disclosure relates to an activity recognition method of a large receptive field (LRF) large-kernel attention convolution network based on a large receptive field, the method includes the following steps: collecting an action signal, carrying out a preprocessing and a data partition on the action signal to obtain a data set; and training an LRF large-kernel attention convolution network model based on the data set, and introducing a trained LRF large-kernel attention convolution network model into a mobile wearable recognition device for human posture recognition.
G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
80.
SILICA-ENCAPSULATED NANO-PHASE CHANGE MATERIAL AND PREPARATION METHOD THEREOF
HAIAN INSTITUTE OF HIGH-TECH RESEARCH, NANJING UNIVERSITY (China)
Inventor
Tang, Shaochun
Jia, Suyue
Yang, Peng
Lu, Hongbin
Wu, Yang
Huang, Ye
Abstract
A silica-encapsulated nano-phase change material and its preparation method are provided. An n-octadecane SiO2 nanoscale phase change material is prepared by sol-gel and microemulsion coupling under alkaline conditions using silica as the shell material and n-octadecane as the core material in a microcapsule and using ethyl n-silicate as the silica source, cetyltrimethylammonium bromide as the emulsifier, and water and ethanol as the solvents. The materials prepared have a particle size of about 500 nm, a phase transition temperature of 27.7° C., a latent heat of phase transition of 159.74 J/g, and an elevated thermal decomposition temperature of 50° C. increase compared with that of the existing n-octadecane.
CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE (China)
HUAZHONG AGRICULTURAL UNIVERSITY (China)
Inventor
Dong, Xianchi
Liu, Wen
Ding, Jianping
Shi, Yu
Xu, Shutong
Xu, Jianbo
Abstract
Provided are a protein comprising an amino acid sequence capable of binding to a substrate GPRP peptide fragment, a fibrinogen like protein 1 (FGL1) comprising the amino acid sequence, and a fibrinogen domain (FD) thereof, and an individual FD protein has the same or similar function as the FGL1. The FGL1 and the FD can inhibit the assembly of fibrin in a thrombogenesis process by competing for a fibrin substrate-binding pocket. By means of mutations, the FGL1 and the FD can have stronger substrate affinity, such that the using effect of a thrombus treatment drug can be effectively enhanced.
An optical phased array device, which can flexibly set the light splitting weight and has good scalability, includes a light splitting network, phase shifters, and emission units. Among them, the light splitting network of the device can set the optical power weight of the array element freely and has good scalability. The light splitting network of optical phased array consists of a series of basic elements, each of which can realize uniform or non-uniform light splitting of N channels. The light splitting network adopts a tree topology. The tree network structure can be freely designed, and the components used by the network nodes can also be freely selected. By freely designing the structure of the light splitting network and the components used by each node, the optical output distribution of the network can be set, so that the far field distribution of the optical phased array can be optimized.
G02B 27/00 - Optical systems or apparatus not provided for by any of the groups ,
G02B 6/28 - Optical coupling means having data bus means, i.e. plural waveguides interconnected and providing an inherently bidirectional system by mixing and splitting signals
83.
METHOD FOR REGULATING THERMAL BOUNDARY CONDUCTANCE BETWEEN METAL AND INSULATOR
Provided is a method for regulating a thermal boundary conductance between a metal and an insulator, including: arranging a metal on a surface of an insulator, a contact surface between the metal and the insulator being a boundary between the metal and the insulator; and the insulator including a ferroelectric, a piezoelectric, or a pyroelectric; applying an external electric field or stress to the ferroelectric, and adjusting a magnitude of the external electric field or stress, or an included angle between a direction of the external electric field or stress with the boundary to regulate the thermal boundary conductance; or applying a stress to the piezoelectric, and adjusting a magnitude of the stress, or an included angle between a direction of the stress with the boundary to regulate the thermal boundary conductancer; or adjusting a temperature of the pyroelectric to regulate the thermal boundary conductance.
H01B 3/00 - Insulators or insulating bodies characterised by the insulating materialsSelection of materials for their insulating or dielectric properties
H01B 1/02 - Conductors or conductive bodies characterised by the conductive materialsSelection of materials as conductors mainly consisting of metals or alloys
H01B 3/10 - Insulators or insulating bodies characterised by the insulating materialsSelection of materials for their insulating or dielectric properties mainly consisting of inorganic substances metallic oxides
H01B 13/00 - Apparatus or processes specially adapted for manufacturing conductors or cables
H01B 13/22 - SheathingArmouringScreeningApplying other protective layers
84.
RNA PLASMID DELIVERY SYSTEM AND APPLICATION THEREOF
Provided are an RNA plasmid delivery system and an application thereof. The RNA plasmid delivery system comprises a plasmid carrying an RNA fragment required to be delivered; the plasmid can be enriched in an organ tissue of a host, and spontaneously forms an exosome containing the RNA fragment in the organ tissue of the host, and therefore can enter and be combined with a target tissue to deliver the RNA fragment into the target tissue. The RNA delivery system is safe, reliable, good in druggability, and strong in universality.
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
85.
VIRAL VECTOR-BASED RNA DELIVERY SYSTEM AND USE THEREOF
Provided are a viral vector-based RNA delivery system and a use thereof. The RNA delivery system comprises a viral vector. The viral vector carries an RNA fragment needing to be delivered, and can be enriched in organ tissues of a host. In the host organ tissues, the viral vector can endogenously and spontaneously form a composite structure containing the RNA fragment. The composite structure can enter and bind to target tissues, and feed the RNA fragment into the target tissues. The viral vector has a targeting tag. The composite structure is an exosome. The viral vector RNA delivery system is safe and reliable, and has good druggability and high universality.
Disclosed are a TLR7-IFN I signaling pathway activated mouse in-vivo cell, a humanized systemic lupus erythematosus mouse having the cell, a construction method for the mouse, and a use of the mouse in medical research. Specifically, a TLR7-IFN I signaling pathway of a cell is activated by administering a TLR7 agonist Resiquimod, such that the mouse exhibits a similar phenotype of a patient with systemic lupus erythematosus, and a plasmid expressing human Flt3L and a DNA derived from autologous activated lymphocytes are injected into the mouse, such that the humoral immune response of B cells of the mouse is promoted, and B cell subpopulation imbalance and autoantibody generation are induced, thereby constructing the humanized systemic lupus erythematosus mouse. According to the humanized systemic lupus erythematosus mouse, immune disorders and corresponding phenotypes are induced in a human immune system, such that the humanized systemic lupus erythematosus mouse is more beneficial to screening a novel targeted drug.
Provided are a gene circuit, an RNA delivery system and the use thereof. Specifically, the gene circuit comprises at least an RNA fragment capable of inhibiting gene expression and/or a targeting tag having a targeting function. The gene circuit can be delivered to a host, enriched in organ tissues of the host and self-assembled to form a complex structure, and inhibits gene expression by means of the RNA fragment, thereby treating diseases. The delivery system comprises the gene circuit and a delivery carrier capable of delivering the gene circuit to organ tissues of a host for enrichment. The provided gene circuit has a targeting function and a treatment function, can quickly and accurately reach target organs and target tissues to exert a treatment effect, and is highly efficient with good results. The safety and reliability of the provided RNA delivery system are fully verified, and the RNA delivery system has good druggability, high universality, and great economic benefits and application prospects.
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
88.
RNA DELIVERY SYSTEM FOR TREATMENT OF HUNTINGTON'S DISEASE
An RNA delivery system for the treatment of Huntington's disease. The system comprises a viral vector, the viral vector carries RNA fragments capable of treating Huntington's disease, the viral vector is capable of enrichment in organ tissues of a host and endogenously and spontaneously forming a complex containing the RNA fragments capable of treating Huntington's disease in the organ tissues of the host, and the complex can deliver the RNA fragments into a target tissue to treat Huntington's disease. The safety and reliability of the RNA delivery system for the treatment of Huntington's disease have been fully verified. The system has good medicinal properties, strong versatility, and has economic benefits and application prospects.
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A61K 9/00 - Medicinal preparations characterised by special physical form
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
The present invention discloses a container equipment for enclosed transportation and heterotopic and aerobic stabilization of reserved garbage, which includes a container body and a functional lining provided on an inner wall of the container body, wherein the functional lining is provided with a circulating air low-temperature evaporation system, a water distribution and drainage system and a heating and insulating system; the circulating air low-temperature evaporation system includes an air inlet manifold, an air distribution perforated pipe, a base plate water discharge and air distribution groove and a top plate water distribution and air guide groove, an air extraction perforated pipe, a fan, an air outlet pipe and a quicklime dehydration and deodorization system; the water distribution and drainage system includes a percolate feeding pipe, a fiber capillary water distribution pipe, the top plate water distribution and air guide groove, a side drain, a main drain and a percolate discharge pipe; the heating and insulating system includes a base plate hydrothermal manifold, a bottom hydrothermal coil, a peripheral hydrothermal layer, a bottom air insulating layer and a peripheral air insulating layer. The present invention also discloses a method for using the container equipment described above. The present invention achieves a fully-enclosed transportation of solid waste and a heterotopic and aerobic stabilization process.
Provided in the present invention are a genetically modified mouse cell, a mouse having a humanized immune system containing said mouse cell, and a construction method for the humanized mouse. The method comprises: inactivating a GFI1 gene on a mouse, and without sublethal irradiation, directly carrying out a humanized modeling process by injecting hematopoietic stem cells, wherein the dosage of the hematopoietic stem cells can be reduced to one eighth of an original reference dose.
A structure of a two-dimensional material-based device having an air-gap and a method for preparing same comprises a substrate, a gate, an dielectric, a two-dimensional material-based film, and source and drain electrodes; the air-gap is formed between the two-dimensional material-based film and the side wall of the dielectric on the gate, or the air-gap is formed between the dielectric and the gate; two-dimensional material-based devices of the above structure utilize the ductility and flexibility of two-dimensional materials to reduce the coupling between the gate and the source/drain electrodes, thereby reducing the parasitic capacitance and the circuit delay; also, the structure ensures that a part of the contact region of the source and drain electrodes with the two-dimensional material can be controlled by the gate, and can thus avoid the reduction in electrical properties and keep a low resistance of the device.
A polycationic polysaccharide and an application thereof is disclosed. Specifically, the polycationic polysaccharide consists of a polysaccharide and a polyamine compound, and is a positively charged polycationic polysaccharide obtained by reacting a polysaccharide with an amine-containing or polyamine compound. The polycationic polysaccharide is applied in a biomedical functional material of an antibacterial biofilm, a biomedical device, and an antibacterial functional material.
C08L 5/00 - Compositions of polysaccharides or of their derivatives not provided for in group or
A61K 31/715 - Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkagesDerivatives thereof, e.g. ethers, esters
A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
93.
Preparation method and application of clay/tannic acid/metal ion composite material for efficient adsorption of antibiotics
QUANZHOU INSTITUTE FOR ENVIRONMENTAL PROTECTION INDUSTRY, NANJING UNIVERSITY (China)
Inventor
Yang, Hu
Chang, Qianqian
Abstract
A preparation method and an application of a clay/tannic acid/metal ion composite material for efficient adsorption of antibiotics are provided, which relate to the field of water environment treatments. A clay/tannic acid/metal ion composite adsorbent is prepared, preparation method and operation process are simple, synthesis time is short, and yield is large. A raw material used is tannic acid, which has a wide range of sources, is non-toxic, biodegradable, and has no risk of secondary pollution, due to abundant phenolic hydroxyl groups in tannic acid, the tannic acid can not only chelate with the metal ions, but also adsorb pollutants from water, when combined with the clay and the metal ions, a composite body is formed, which has a rougher surface, and adsorption active sites are increased, thereby effectively increasing adsorption, and improving an adsorption performance for pollutants. The clay/tannic acid/metal ion composite adsorbent has good adsorption effect for antibiotics.
C02F 1/28 - Treatment of water, waste water, or sewage by sorption
B01J 20/02 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material
B01J 20/12 - Naturally occurring clays or bleaching earth
B01J 20/24 - Naturally occurring macromolecular compounds, e.g. humic acids or their derivatives
B01J 20/30 - Processes for preparing, regenerating or reactivating
It is disclosed a method and system based on machine learning for reconstructing biological wastewater treatment processes; the method includes: acquiring influent and effluent basic quality, ecological risk and process information data on the biological wastewater treatment process, and performing data preprocessing; performing feature extraction and multi-unit characterization on the biological wastewater treatment process; constructing effluent basic quality prediction models and effluent ecological risk prediction models of different biological treatment multi-unit combination processes, and performing standard-reaching validation; simulating and reconstructing different biological wastewater treatment short-range unit combination processes, and performing effluent quality standard-reaching validation under different influent quality scenarios; and evaluating ecological risk of the reconstructed short-range biological treatment unit combination processes with the effluent quality up to standard, and determining the optimal biological wastewater treatment process.
The present disclosure discloses a method for modifying a DNA by utilizing a glycosylase and an oxyamine compound, including the following steps: conducting solid phase synthesis of a DNA strand carrying a non-canonical base; reacting the DNA strand carrying a non-canonical base under the catalysis of the glycosylase which selectively recognizes the non-canonical base, to produce a DNA strand carrying an abasic site; and reacting the DNA strand carrying the abasic site with the oxyamine compound to generate a DNA modified with a chemical functional group. This method can realize diverse site-directed modification of the DNA, can be used to study the base structure-function relationship of a functional DNA, and construct a functional DNA with higher activity. The present method is simple and easy to use, and can reduce the cost and the time required for modification. The modified functional DNA has higher activity and can provide better tool molecules for biotechnology, disease diagnosis and treatment.
Haian Institute of High-Tech Research, Nanjing University (China)
Inventor
Tang, Shaochun
Zhang, Rong
Xiang, Bo
Shen, Yuchun
Abstract
Disclosed is a method for preparing a three-dimensional porous nano composite cooling film in large scale. The cooling film is prepared from 0.1-0.5 parts of cellulose acetate, 1-5 parts of water, 20-100 parts of acetone, an additive, and 10-20 parts of nano microspheres through a cooperative formulation of cellulose acetate, nano microsphere materials and the additive. The composite cooling film is obtained by self-deposition of cellulose acetate and nano microspheres, and liquid volatilization during film forming process leads to formation of the three-dimensional porous structure. The film has an effect of enhancing radiation of infrared heat into space, which could significantly reduce a temperature of a substrate surface and achieve rapid and strong cooling. The film could achieve effective cooling without external power and other active cooling equipment, with or without sunlight.
C04B 26/28 - Polysaccharides or derivatives thereof
B29C 39/00 - Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressureApparatus therefor
C04B 20/00 - Use of materials as fillers for mortars, concrete or artificial stone according to more than one of groups and characterised by shape or grain distributionTreatment of materials according to more than one of the groups specially adapted to enhance their filling properties in mortars, concrete or artificial stoneExpanding or defibrillating materials
C04B 38/00 - Porous mortars, concrete, artificial stone or ceramic warePreparation thereof
C04B 40/00 - Processes, in general, for influencing or modifying the properties of mortars, concrete or artificial stone compositions, e.g. their setting or hardening ability
97.
PHOTORESIST-FREE OPTICAL PATTERNING METHOD FOR COLLOIDAL NANOCRYSTALS IN GREEN SOLVENT
The present invention relates to the technical field of nanomaterials and optical etching, and provides a photoresist-free optical patterning method for colloidal nanocrystals in a green solvent. A photosensitive ligand structurally similar to the green solvent is introduced to successfully disperse nanocrystals in the green solvent and perform photolithography directly on the nanocrystals. Photosensitive nanocrystals obtained through ligand exchange can be effectively dispersed in the green solvent to absorb an emission spectrum emitted by the green solvent, thereby preserving about 90% of photoluminescence quantum yield (PLQY) while keeping the morphology and size unchanged. The scheme solves the problem that nanocrystals cannot be subject to direct photolithography in the green solvent, and is expected to be applied to the commercialization of nanocrystals in the field of electroluminescent and photoluminescent quantum dot displays.
The present disclosure relates to a solar battery including a first cell, and a second cell, and a first charge transport layer, a transparent conductive layer, a second charge transport layer and a polysilicon layer are disposed between the first photoelectric conversion layer of the first cell and the second photoelectric conversion layer of the second cell, and the second charge transport layer is disposed between the polysilicon layer and the transparent conductive layer, and the charge transport property of the second charge transport layer is the same as that of the polysilicon layer. In the solar battery of the present disclosure, a first charge transport layer, a transparent conductive layer, a second charge transport layer and a polysilicon layer are sequentially arranged between the first photoelectric conversion layer and the second photoelectric conversion layer. Especially the second charge transport layer may protect the polysilicon layer, may effectively transport the same type of charges, and avoid recombination phenomena at the interface or inside the film, thereby effectively improving the efficiency of the battery. The solar battery of this disclosure also has the characteristics of simple structure, simple and convenient manufacturing process, and low cost.
H10K 30/57 - Photovoltaic [PV] devices comprising multiple junctions, e.g. tandem PV cells
H10K 30/40 - Organic devices sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation comprising a p-i-n structure, e.g. having a perovskite absorber between p-type and n-type charge transport layers
99.
DEVICE AND METHOD FOR PARALLELIZING ANALOG IN-MEMORY COMPUTING BASED ON FREQUENCY DIVISION MULTIPLEXING
A device for parallelizing analog in-memory computing based on frequency division multiplexing comprises an input circuit, a memory array and an output circuit, wherein an input of the memory array is connected with an output of the input circuit, and an output of the memory array is connected with an input of the output circuit; the input circuit modulates k data in each row of m×k input data matrix into each path of frequency division multiplexing signals for output by using k different frequency sources; the memory array comprises m×n memory elements, memory weights thereof form an m×n matrix, and m×1 input frequency division multiplexing signals are parallel-processed in the memory array; and the output circuit demodulates and separates each path of frequency division multiplexing signals output by the memory array into k data.
ECL-BASED ELECTRODE, MANUFACTURING METHOD FOR ECL-BASED ELECTRODE, ECL SENSOR, MANUFACTURING METHOD FOR ECL SENSOR, METHOD FOR ECL DETECTION OF NUCLEIC ACID-SPECIFIC SITE MODIFICATION, AND KIT FOR NUCLEIC ACID MODIFICATION DETECTION USED FOR METHOD FOR ECL DETECTION OF NUCLEIC ACID-SPECIFIC SITE MODIFICATION
A manufacturing method for an ECL (Electrochemiluminescence)-based electrode according to an embodiment includes a step of mixing an electrocatalytic solution and metal nanoparticles and thereafter dropping a mixed particle suspension onto the surface of an electrode and obtaining a base electrode co-modified by an electrocatalyst-metal nanoparticle.
G01N 21/66 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
