Mileutis Ltd.

Israel

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2025 (YTD) 1
2024 3
2023 6
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2020 4
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IPC Class
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans 8
A61K 38/01 - Hydrolysed proteinsDerivatives thereof 7
A61K 38/00 - Medicinal preparations containing peptides 5
A61K 38/07 - Tetrapeptides 5
A61K 38/08 - Peptides having 5 to 11 amino acids 5
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Status
Pending 3
Registered / In Force 22

1.

USE OF COMPOSITION COMPRISING CASEIN HYDROLYSATE FOR THE TREATMENT OF INFLAMMATORY SKIN CONDITIONS

      
Application Number IL2024050732
Publication Number 2025/022394
Status In Force
Filing Date 2024-07-24
Publication Date 2025-01-30
Owner MILEUTIS LTD. (Israel)
Inventor
  • Iscovich, Javier
  • Iscovich, Jose Mario

Abstract

The present invention provides a method for preventing or treating inflammatory skin conditions, by administering a composition comprising at least one milk derived protein. The present invention further relates to a method for moisturizing dry skin, skin softening, reducing skin itching, reducing skin peeling, reducing skin redness, reducing rough skin, reducing skin swelling, reducing skin cracking, renewal skin cells, preserving hand skin or any combination thereof.

IPC Classes  ?

  • A61K 35/20 - MilkWheyColostrum
  • A61K 8/64 - ProteinsPeptidesDerivatives or degradation products thereof
  • A61K 38/01 - Hydrolysed proteinsDerivatives thereof
  • A61P 17/00 - Drugs for dermatological disorders
  • A61P 37/00 - Drugs for immunological or allergic disorders
  • A61Q 19/00 - Preparations for care of the skin

2.

ENHANCED MILK QUALITY

      
Application Number IL2024050486
Publication Number 2024/236580
Status In Force
Filing Date 2024-05-16
Publication Date 2024-11-21
Owner MILEUTIS LTD. (Israel)
Inventor
  • Iscovich, Jose Mario
  • Iscovich, Javier

Abstract

The current disclosure relates to a method of increasing milk quality in lactating mammals comprising administering a composition comprising at least one casein derived peptide.

IPC Classes  ?

  • A23C 9/00 - Milk preparationsMilk powder or milk powder preparations
  • A23C 9/12 - Fermented milk preparationsTreatment using microorganisms or enzymes
  • A23C 9/142 - Milk preparationsMilk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
  • A23C 9/20 - Dietetic milk products not covered by groups
  • A23C 19/05 - Treating milk before coagulationSeparating whey from curd
  • A23J 1/20 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from milk, e.g. caseinObtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from whey
  • A23J 3/10 - Casein
  • A23L 33/19 - Dairy proteins
  • A23L 33/00 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof
  • A61K 38/01 - Hydrolysed proteinsDerivatives thereof
  • A61K 38/07 - Tetrapeptides
  • A61K 38/08 - Peptides having 5 to 11 amino acids
  • A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
  • C07K 5/103 - Tetrapeptides the side chain of the first amino acid being acyclic, e.g. Gly, Ala
  • C07K 5/11 - Tetrapeptides the side chain of the first amino acid containing more amino groups than carboxyl groups, or derivatives thereof, e.g. Lys, Arg
  • C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
  • A23K 10/10 - Animal feeding-stuffs obtained by microbiological or biochemical processes
  • A23K 10/20 - Animal feeding-stuffs from material of animal origin
  • A23K 20/147 - Polymeric derivatives, e.g. peptides or proteins
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants

3.

COMPOSITIONS AND METHODS FOR MODULATING MAMMARY DISORDERS AND CONDITIONS

      
Application Number 18557393
Status Pending
Filing Date 2022-04-28
First Publication Date 2024-06-27
Owner MILEUTIS LTD. (Israel)
Inventor
  • Iscovich, Jose Mario
  • Iscovich, Javier

Abstract

The present disclosure provides compositions and methods for modulating various mammary' disorders and conditions. The disclosure further provides a therapeutic combination of a composition of at least one casein protein or casein-derived peptide; and a teat seal composition.

IPC Classes  ?

  • A61K 38/01 - Hydrolysed proteinsDerivatives thereof
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 33/245 - BismuthCompounds thereof
  • A61K 38/07 - Tetrapeptides
  • A61K 38/08 - Peptides having 5 to 11 amino acids
  • A61K 38/10 - Peptides having 12 to 20 amino acids
  • A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
  • A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

4.

COMPOSITIONS AND METHODS FOR MODULATING MAMMARY DISORDERS AND CONDITIONS

      
Application Number IL2023051181
Publication Number 2024/105668
Status In Force
Filing Date 2023-11-15
Publication Date 2024-05-23
Owner MILEUTIS LTD. (Israel)
Inventor
  • Iscovich, Jose Mario
  • Iscovich, Javier

Abstract

The present invention provides compositions and methods for treating intramammary infection in lactating mammals during lactation and providing a continuous milk production and milking in lactating mammals during lactation, wherein somatic cell count in milk, milk electrical conductivity or combination thereof are increased.

IPC Classes  ?

  • A61K 35/20 - MilkWheyColostrum
  • A61K 38/01 - Hydrolysed proteinsDerivatives thereof
  • A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
  • A61K 38/38 - Albumins
  • A61K 38/40 - Transferrins, e.g. lactoferrins, ovotransferrins
  • A61P 15/14 - Drugs for genital or sexual disordersContraceptives for lactation disorders, e.g. galactorrhoea

5.

Miscellaneous Design

      
Application Number 1724571
Status Registered
Filing Date 2023-03-21
Registration Date 2023-03-21
Owner MILEUTIS LTD (Israel)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Intramammary and intrauterine veterinary preparations; intramammary and intrauterine pharmaceutical and medical preparations for human use; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of mastitis, breast inflammation, mammary infections, and mammary disorders; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of metritis; pharmaceutical preparations, veterinary preparations, and medical preparations for the prevention and treatment of uterine infections; veterinary preparations for increasing milk production and improving feed efficiency; animal feed additive for use as a nutritional supplement for medical purposes; pharmaceutical and medical preparations for increasing milk production; veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations and medical preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations, veterinary preparations and medical preparations for the involution of the udder or the mammary gland; pharmaceutical preparations, veterinary preparations and medical preparations for reduction of somatic cell count; veterinary preparations, and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms related to infections in lactating animals during the lactation period; veterinary and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in lactating animals; pharmaceutical and medical preparations for the prevention and treatment of lactation-related medical conditions; pharmaceutical preparations, veterinary preparations and medical preparations for the treatment and prevention of infections, diseases, disorders and conditions in poultry, and for promoting growth or the welfare of poultry; pharmaceutical and medical preparations for the prevention or treatment of buccal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of central, peripherical and neuronal nervous system conditions; pharmaceutical and medical preparations for the prevention or treatment of gastro-intestinal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of diseases, disorders and conditions of the skeletal system and the bones; medical and veterinary preparations to regulate and adapt the mammalian gut microbiome for disease prevention and wellness; pharmaceutical preparations, medical preparations, and veterinary preparations for the treatment of wounds, or damages to the skin and tissues; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of dermatological disorders, or skin diseases, disorders and conditions related to hyperactive immune response, or allergic reactions and conditions; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of medical conditions and diseases associated with immunostimulation or immunomodulation; synthetic and biological peptides for the treatment of conditions and diseases associated with immunostimulation, or for immunomodulation; pharmaceutical, medical and veterinary preparations.

6.

MILEUTIS

      
Application Number 1724572
Status Registered
Filing Date 2023-03-21
Registration Date 2023-03-21
Owner MILEUTIS LTD (Israel)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Intramammary and intrauterine veterinary preparations; intramammary and intrauterine pharmaceutical and medical preparations for human use; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of mastitis, breast inflammation, mammary infections, and mammary disorders; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of metritis; pharmaceutical preparations, veterinary preparations, and medical preparations for the prevention and treatment of uterine infections; veterinary preparations for increasing milk production and improving feed efficiency; animal feed additive for use as a nutritional supplement for medical purposes; pharmaceutical and medical preparations for increasing milk production; veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations and medical preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations, veterinary preparations and medical preparations for the involution of the udder or the mammary gland; pharmaceutical preparations, veterinary preparations and medical preparations for reduction of somatic cell count; veterinary preparations, and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms related to infections in lactating animals during the lactation period; veterinary and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in lactating animals; pharmaceutical and medical preparations for the prevention and treatment of lactation-related medical conditions; pharmaceutical preparations, veterinary preparations and medical preparations for the treatment and prevention of infections, diseases, disorders and conditions in poultry, and for promoting growth or the welfare of poultry; pharmaceutical and medical preparations for the prevention or treatment of buccal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of central, peripherical and neuronal nervous system conditions; pharmaceutical and medical preparations for the prevention or treatment of gastro-intestinal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of diseases, disorders and conditions of the skeletal system and the bones; medical and veterinary preparations to regulate and adapt the mammalian gut microbiome for disease prevention and wellness; pharmaceutical preparations, medical preparations, and veterinary preparations for the treatment of wounds, or damages to the skin and tissues; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of dermatological disorders, or skin diseases, disorders and conditions related to hyperactive immune response, or allergic reactions and conditions; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of medical conditions and diseases associated with immunostimulation or immunomodulation; synthetic and biological peptides for the treatment of conditions and diseases associated with immunostimulation, or for immunomodulation; pharmaceutical, medical and veterinary preparations.

7.

Geometric Shape design

      
Application Number 225177700
Status Pending
Filing Date 2023-03-21
Owner MILEUTIS LTD (Israel)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

(1) Intramammary and intrauterine veterinary preparations; intramammary and intrauterine pharmaceutical and medical preparations for human use; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of mastitis, breast inflammation, mammary infections, and mammary disorders; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of metritis; pharmaceutical preparations, veterinary preparations, and medical preparations for the prevention and treatment of uterine infections; veterinary preparations for increasing milk production and improving feed efficiency; animal feed additive for use as a nutritional supplement for medical purposes; pharmaceutical and medical preparations for increasing milk production; veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations and medical preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations, veterinary preparations and medical preparations for the involution of the udder or the mammary gland; pharmaceutical preparations, veterinary preparations and medical preparations for reduction of somatic cell count; veterinary preparations, and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms related to infections in lactating animals during the lactation period; veterinary and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in lactating animals; pharmaceutical and medical preparations for the prevention and treatment of lactation-related medical conditions; pharmaceutical preparations, veterinary preparations and medical preparations for the treatment and prevention of infections, diseases, disorders and conditions in poultry, and for promoting growth or the welfare of poultry; pharmaceutical and medical preparations for the prevention or treatment of buccal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of central, peripherical and neuronal nervous system conditions; pharmaceutical and medical preparations for the prevention or treatment of gastro-intestinal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of diseases, disorders and conditions of the skeletal system and the bones; medical and veterinary preparations to regulate and adapt the mammalian gut microbiome for disease prevention and wellness; pharmaceutical preparations, medical preparations, and veterinary preparations for the treatment of wounds, or damages to the skin and tissues; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of dermatological disorders, or skin diseases, disorders and conditions related to hyperactive immune response, or allergic reactions and conditions; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of medical conditions and diseases associated with immunostimulation or immunomodulation; synthetic and biological peptides for the treatment of conditions and diseases associated with immunostimulation, or for immunomodulation; pharmaceutical, medical and veterinary preparations.

8.

MILEUTIS

      
Application Number 225177800
Status Pending
Filing Date 2023-03-21
Owner MILEUTIS LTD (Israel)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

(1) Intramammary and intrauterine veterinary preparations; intramammary and intrauterine pharmaceutical and medical preparations for human use; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of mastitis, breast inflammation, mammary infections, and mammary disorders; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of metritis; pharmaceutical preparations, veterinary preparations, and medical preparations for the prevention and treatment of uterine infections; veterinary preparations for increasing milk production and improving feed efficiency; animal feed additive for use as a nutritional supplement for medical purposes; pharmaceutical and medical preparations for increasing milk production; veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations and medical preparations for the prevention and treatment of bacterial infections, disorders, conditions, and diseases; pharmaceutical preparations, veterinary preparations and medical preparations for the involution of the udder or the mammary gland; pharmaceutical preparations, veterinary preparations and medical preparations for reduction of somatic cell count; veterinary preparations, and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms related to infections in lactating animals during the lactation period; veterinary and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in lactating animals; pharmaceutical and medical preparations for the prevention and treatment of lactation-related medical conditions; pharmaceutical preparations, veterinary preparations and medical preparations for the treatment and prevention of infections, diseases, disorders and conditions in poultry, and for promoting growth or the welfare of poultry; pharmaceutical and medical preparations for the prevention or treatment of buccal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of central, peripherical and neuronal nervous system conditions; pharmaceutical and medical preparations for the prevention or treatment of gastro-intestinal diseases, disorders and conditions; pharmaceutical and medical preparations for the prevention or treatment of diseases, disorders and conditions of the skeletal system and the bones; medical and veterinary preparations to regulate and adapt the mammalian gut microbiome for disease prevention and wellness; pharmaceutical preparations, medical preparations, and veterinary preparations for the treatment of wounds, or damages to the skin and tissues; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of dermatological disorders, or skin diseases, disorders and conditions related to hyperactive immune response, or allergic reactions and conditions; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of medical conditions and diseases associated with immunostimulation or immunomodulation; synthetic and biological peptides for the treatment of conditions and diseases associated with immunostimulation, or for immunomodulation; pharmaceutical, medical and veterinary preparations.

9.

Miscellaneous Design

      
Serial Number 79367537
Status Registered
Filing Date 2023-03-21
Registration Date 2025-01-07
Owner MILEUTIS LTD (Israel)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Intramammary and intrauterine veterinary preparations for treating mastitis, mammary infections, uterine infections, myometrium infection and intrauterine infections; intramammary and intrauterine pharmaceutical and medical preparations for human use for treating mastitis, mammary infections, and intrauterine infections; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of mastitis, breast inflammation, mammary infections and mammary inflammation; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of metritis; pharmaceutical preparations, veterinary preparations, and medical preparations for the prevention and treatment of uterine infections; veterinary preparations for increasing milk production and improving feed efficiency, namely for treating gastro-intestinal diseases, anorexia, and for use as growth promoters; animal feed additive for use as a nutritional supplement for medical purposes; pharmaceutical and medical preparations for increasing milk production, namely for treating mastitis, mammary infections, and for involution of the mammary glands; veterinary preparations for the prevention and treatment of bacterial infections; pharmaceutical preparations and medical preparations for the prevention and treatment of bacterial infections; pharmaceutical preparations, veterinary preparations and medical preparations for mammary and udder involution; pharmaceutical preparations, veterinary preparations and medical preparations for reduction of somatic cell count in milk, namely for treating mammary and udder inflammations; veterinary preparations, and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms related to infections in lactating animals during the lactation period; veterinary and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in lactating animals, namely for treating mammary pain, mammary infections, and edema; pharmaceutical and medical preparations for the prevention and treatment of lactation-related medical conditions, namely for treating mammary pain, mammary infections, and edema; pharmaceutical preparations, veterinary preparations and medical preparations for the treatment and prevention of infections in poultry, and for use as growth promoters of poultry; pharmaceutical and medical preparations for the prevention or treatment of buccal diseases, disorders and conditions, namely mucositis and buccal infections; pharmaceutical and medical preparations for the prevention or treatment of central, peripherical and neuronal nervous systems diseases; pharmaceutical and medical preparations for the prevention or treatment of gastro-intestinal diseases; pharmaceutical and medical preparations for the prevention or treatment of diseases of the musculo-skeletal system; medical and veterinary preparations to regulate and adapt the mammalian gut microbiome for disease prevention and wellness; pharmaceutical preparations, medical preparations, and veterinary preparations for the treatment of wounds, and damages to the skin and tissues, namely skin and tissue infections; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of dermatological disorders, and skin diseases, related to hyperactive immune response, or allergies; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of immunostimulation and immunomodulation; synthetic and biological peptides for the treatment of immunostimulation, and immunomodulation; pharmaceutical, medical and veterinary preparations to regulate and adapt the mammalian buccal, gastrointestinal and vaginal-vulvar microbiome for disease prevention and wellness

10.

MILEUTIS

      
Serial Number 79367538
Status Registered
Filing Date 2023-03-21
Registration Date 2025-01-07
Owner MILEUTIS LTD (Israel)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Intramammary and intrauterine veterinary preparations for treating mastitis, mammary infections, uterine infections, myometrium infection and intrauterine infections; intramammary and intrauterine pharmaceutical and medical preparations for human use for treating mastitis, mammary infections, and intrauterine infections; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of mastitis, breast inflammation, mammary infections and mammary inflammation; pharmaceutical preparations, veterinary preparations, and medical preparations for the treatment and prevention of metritis; pharmaceutical preparations, veterinary preparations, and medical preparations for the prevention and treatment of uterine infections; veterinary preparations for increasing milk production and improving feed efficiency, namely for treating gastro-intestinal diseases, anorexia, and for use as growth promoters; animal feed additive for use as a nutritional supplement for medical purposes; pharmaceutical and medical preparations for increasing milk production, namely for treating mastitis, mammary infections, and for involution of the mammary glands; veterinary preparations for the prevention and treatment of bacterial infections; pharmaceutical preparations and medical preparations for the prevention and treatment of bacterial infections; pharmaceutical preparations, veterinary preparations and medical preparations for mammary and udder involution; pharmaceutical preparations, veterinary preparations and medical preparations for reduction of somatic cell count in milk, namely for treating mammary and udder inflammations; veterinary preparations, and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms related to infections in lactating animals during the lactation period; veterinary and pharmaceutical preparations for increasing the welfare and comfort of lactating animals, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in lactating animals, namely for treating mammary pain, mammary infections, and edema; pharmaceutical and medical preparations for the prevention and treatment of lactation-related medical conditions, namely for treating mammary pain, mammary infections, and edema; pharmaceutical preparations, veterinary preparations and medical preparations for the treatment and prevention of infections in poultry, and for use as growth promoters of poultry; pharmaceutical and medical preparations for the prevention or treatment of buccal diseases, disorders and conditions, namely mucositis and buccal infections; pharmaceutical and medical preparations for the prevention or treatment of central, peripherical and neuronal nervous systems diseases; pharmaceutical and medical preparations for the prevention or treatment of gastro-intestinal diseases; pharmaceutical and medical preparations for the prevention or treatment of diseases of the musculo-skeletal system; medical and veterinary preparations to regulate and adapt the mammalian gut microbiome for disease prevention and wellness; pharmaceutical preparations, medical preparations, and veterinary preparations for the treatment of wounds, and damages to the skin and tissues, namely skin and tissue infections; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of dermatological disorders, and skin diseases, related to hyperactive immune response, or allergies; pharmaceutical preparations, medical preparations, and veterinary preparations for the prevention and treatment of immunostimulation and immunomodulation; synthetic and biological peptides for the treatment of immunostimulation, and immunomodulation; pharmaceutical, medical and veterinary preparations to regulate and adapt the mammalian buccal, gastrointestinal and vaginal-vulvar microbiome for disease prevention and wellness

11.

COMPOSITIONS AND METHODS FOR MODULATING MAMMARY DISORDERS AND CONDITIONS

      
Application Number IL2022050442
Publication Number 2022/229965
Status In Force
Filing Date 2022-04-28
Publication Date 2022-11-03
Owner MILEUTIS LTD. (Israel)
Inventor
  • Iscovich, Jose Mario
  • Iscovich, Javier

Abstract

The present disclosure provides compositions and methods for modulating various mammary' disorders and conditions. The disclosure further provides a therapeutic combination of a composition of at least one casein protein or casein-derived peptide; and a teat seal composition.

IPC Classes  ?

  • A61K 38/07 - Tetrapeptides
  • A61K 38/08 - Peptides having 5 to 11 amino acids
  • A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
  • A61K 31/29 - Antimony or bismuth compounds
  • C07K 5/10 - Tetrapeptides
  • C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
  • A61P 15/14 - Drugs for genital or sexual disordersContraceptives for lactation disorders, e.g. galactorrhoea
  • A61P 31/04 - Antibacterial agents

12.

IMILAC

      
Application Number 221151500
Status Registered
Filing Date 2022-09-01
Registration Date 2025-05-02
Owner Mileutis Ltd. (Israel)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

(1) Veterinary preparations for use in livestock for the prevention and treatment of mastitis and mammary infections; veterinary and pharmaceutical preparations for the treatment and prevention of mastitis in livestock; animal production efficiency enhancing veterinary preparations to aid in milk production in lactating animals and improving feed efficiency; veterinary preparations for the prevention and treatment of intramammary infections; veterinary and pharmaceutical preparations for the involution of the mammary gland in livestock; veterinary and pharmaceutical preparations for shortening the dry-off period in livestock; veterinary and pharmaceutical preparations for reduction of somatic cell count in livestock; veterinary and pharmaceutical preparations for increasing the welfare and comfort of livestock, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in livestock

13.

MILAC

      
Application Number 221151600
Status Registered
Filing Date 2022-09-01
Registration Date 2025-05-02
Owner Mileutis Ltd. (Israel)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

(1) Veterinary preparations for use in livestock for the prevention and treatment of mastitis and mammary infections; veterinary and pharmaceutical preparations for the treatment and prevention of mastitis in livestock; veterinary preparations for the prevention and treatment of intramammary infections; veterinary and pharmaceutical preparations for the involution of the mammary gland in livestock; veterinary and pharmaceutical preparations for reduction of somatic cell count in livestock; veterinary and pharmaceutical preparations for increasing the welfare and comfort of livestock, namely, to reduce, eliminate and treat symptoms related to infections in livestock during the lactation period

14.

IMILAC

      
Application Number 1568067
Status Registered
Filing Date 2020-05-21
Registration Date 2020-05-21
Owner Mileutis Ltd. (Israel)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Veterinary products, namely, preparations for use in livestock; veterinary and pharmaceutical preparations for the treatment and prevention of mastitis in livestock; animal production efficiency enhancing veterinary preparations for increasing milk production and improving feed efficiency; intramammary veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions and diseases; veterinary and pharmaceutical preparations for the involution of the mammary gland in livestock; veterinary and pharmaceutical preparations for shortening the dry-off period in livestock; veterinary and pharmaceutical preparations for reduction of somatic cell count in livestock; veterinary and pharmaceutical preparations for increasing the welfare and comfort of livestock, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in livestock.

15.

MILAC

      
Application Number 1541371
Status Registered
Filing Date 2020-05-21
Registration Date 2020-05-21
Owner Mileutis Ltd. (Israel)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Veterinary products, namely, preparations for use in livestock; veterinary and pharmaceutical preparations for the treatment and prevention of mastitis in livestock; intramammary veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions and diseases; veterinary and pharmaceutical preparations for the involution of the mammary gland in livestock; veterinary and pharmaceutical preparations for reduction of somatic cell count in livestock; veterinary and pharmaceutical preparations for increasing the welfare and comfort of livestock, namely, to reduce, eliminate and treat symptoms related to infections in livestock during the lactation period.

16.

IMILAC

      
Serial Number 79301189
Status Registered
Filing Date 2020-05-21
Registration Date 2021-07-27
Owner Mileutis Ltd. (Israel)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Veterinary and pharmaceutical preparations for the treatment and prevention of mastitis in livestock; animal production efficiency enhancing veterinary preparations for increasing milk production and improving feed efficiency; intramammary veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions and diseases; veterinary and pharmaceutical preparations for the involution of the mammary gland in livestock; veterinary and pharmaceutical preparations for shortening the dry-off period in livestock; veterinary and pharmaceutical preparations for reduction of somatic cell count in livestock; veterinary and pharmaceutical preparations for increasing the welfare and comfort of livestock, namely, to reduce, eliminate and treat symptoms involved with the dry-off period in livestock

17.

MILAC

      
Serial Number 79289809
Status Registered
Filing Date 2020-05-21
Registration Date 2021-03-16
Owner Mileutis Ltd. (Israel)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Veterinary and pharmaceutical preparations for the treatment and prevention of mastitis in livestock; intramammary veterinary preparations for the prevention and treatment of bacterial infections, disorders, conditions and diseases; veterinary and pharmaceutical preparations for the involution of the mammary gland in livestock; veterinary and pharmaceutical preparations for reduction of somatic cell count in livestock; veterinary and pharmaceutical preparations for increasing the welfare and comfort of livestock, namely, to reduce, eliminate and treat symptoms related to infections in livestock during the lactation period

18.

Casein peptide for use in the treatment of uterine infections

      
Application Number 14946186
Grant Number 09861678
Status In Force
Filing Date 2015-11-19
First Publication Date 2016-11-10
Grant Date 2018-01-09
Owner Mileutis Ltd. (Israel)
Inventor Iscovich, Jose Mario

Abstract

The present disclosure relates to a casein peptide for use in the treatment of an uterine infection in a female mammalian animal, to methods of treatment of such infections by administering to a female mammalian animal at least one casein peptide, to the use of casein peptide for the preparation of a pharmaceutical composition for treatment of uterine infection and to a kit for said treatment. The casein peptide is preferably a casein hydrolysate, e.g. obtained by trypsin hydrolysis of casein protein. The female mammalian animal is, in accordance with some embodiments, a lactating animal, the infection being a post-partum infection.

IPC Classes  ?

  • A01N 37/18 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N, e.g. carboxylic acid amides or imidesThio-analogues thereof
  • A61K 38/00 - Medicinal preparations containing peptides
  • A61P 31/04 - Antibacterial agents
  • A61K 38/01 - Hydrolysed proteinsDerivatives thereof
  • A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/20 - MilkWheyColostrum

19.

Peptides for management of lactation

      
Application Number 14384395
Grant Number 09487557
Status In Force
Filing Date 2013-03-08
First Publication Date 2015-04-02
Grant Date 2016-11-08
Owner MILEUTIS LTD. (Israel)
Inventor
  • Iscovich, Jose Mario
  • Iscovich, Javier

Abstract

The present invention provides novel short peptides that are highly effective in inducing involution in a mammary gland of a lactating mammal and cessation of milk production by the gland. The invention further provides pharmaceutical composition comprising the peptides and methods of use thereof including for treating microbial infection in a mammary gland.

IPC Classes  ?

  • C07K 1/00 - General processes for the preparation of peptides
  • C07K 5/00 - Peptides having up to four amino acids in a fully defined sequenceDerivatives thereof
  • C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
  • A61K 38/07 - Tetrapeptides
  • A61K 38/08 - Peptides having 5 to 11 amino acids
  • C07K 5/11 - Tetrapeptides the side chain of the first amino acid containing more amino groups than carboxyl groups, or derivatives thereof, e.g. Lys, Arg
  • C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans

20.

PEPTIDES FOR MANAGEMENT OF LACTATION

      
Application Number IL2013050214
Publication Number 2013/140388
Status In Force
Filing Date 2013-03-08
Publication Date 2013-09-26
Owner MILEUTIS LTD. (Israel)
Inventor
  • Iscovich, Jose Mario
  • Iscovich, Javier

Abstract

The present invention provides novel short peptides that are highly effective in inducing involution in a mammary gland of a lactating mammal and cessation of milk production by the gland. The invention further provides pharmaceutical composition comprising the peptides and methods of use thereof including for treating microbial infection in a mammary gland.

IPC Classes  ?

  • C07K 5/10 - Tetrapeptides
  • C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
  • C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
  • A61K 38/07 - Tetrapeptides
  • A61K 38/08 - Peptides having 5 to 11 amino acids
  • A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans

21.

Casein peptide for use in the treatment of uterine infections

      
Application Number 13641959
Grant Number 09220751
Status In Force
Filing Date 2011-04-17
First Publication Date 2013-05-02
Grant Date 2015-12-29
Owner Mileutis Ltd. (Israel)
Inventor Iscovich, Jose Mario

Abstract

The present disclosure relates to a casein peptide for use in the treatment of an uterine infection in a female mammalian animal, to methods of treatment of such infections by administering to a female mammalian animal at least one casein peptide, to the use of casein peptide for the preparation of a pharmaceutical composition for treatment of uterine infection and to a kit for said treatment. The casein peptide is preferably a casein hydrolysate, e.g. obtained by trypsin hydrolysis of casein protein. The female mammalian animal is, in accordance with some embodiments, a lactating animal, the infection being a post-partum infection.

IPC Classes  ?

  • A01N 37/18 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N, e.g. carboxylic acid amides or imidesThio-analogues thereof
  • A61K 38/00 - Medicinal preparations containing peptides
  • A61P 31/04 - Antibacterial agents
  • A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
  • A61K 38/01 - Hydrolysed proteinsDerivatives thereof

22.

CASEIN PEPTIDE FOR USE IN THE TREATMENT OF UTERINE INFECTIONS

      
Application Number IL2011000325
Publication Number 2011/132191
Status In Force
Filing Date 2011-04-17
Publication Date 2011-10-27
Owner MILEUTIS LTD. (Israel)
Inventor Iscovich, Jose Mario

Abstract

The present disclosure relates to a casein peptide for use in the treatment of an uterine infection in a female mammalian animal, to methods of treatment of such infections by administering to a female mammalian animal at least one casein peptide, to the use of casein peptide for the preparation of a pharmaceutical composition for treatment of uterine infection and to a kit for said treatment. The casein peptide is preferably a casein hydrolysate, e.g. obtained by trypsin hydrolysis of casein protein. The female mammalian animal is, in accordance with some embodiments, a lactating animal, the infection being a post-partum infection.

IPC Classes  ?

  • A61K 38/01 - Hydrolysed proteinsDerivatives thereof
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups

23.

Pharmaceutical compositions comprising casein derived peptides and methods of use thereof

      
Application Number 13107331
Grant Number 08338363
Status In Force
Filing Date 2011-05-13
First Publication Date 2011-09-01
Grant Date 2012-12-25
Owner
  • Mileutis Ltd. (Israel)
  • State of Israel, Ministry of Agriculture & Rural Development, Agriculture Research Organization (Israel)
Inventor
  • Iscovich, Jose Mario
  • Silanikove, Nissim
  • Iscovich, Javier

Abstract

The present invention relates to peptides derived from casein and their use in the management of lactating animals, particularly to methods for decreasing the length of the dry period of a lactating livestock animal, for increasing its milk yield and milk hygiene after parturition and for improving the livestock welfare. The present invention further relates to pharmaceutical compositions comprising peptides derived from casein in the form of a sterile solution, which compositions are clear and substantially devoid of micelles.

IPC Classes  ?

  • A61K 38/00 - Medicinal preparations containing peptides
  • A61P 3/02 - Nutrients, e.g. vitamins, minerals
  • C07K 2/00 - Peptides of undefined number of amino acidsDerivatives thereof

24.

Pharmaceutical compositions comprising casein derived peptides and methods of use thereof

      
Application Number 11913239
Grant Number 07968513
Status In Force
Filing Date 2006-05-02
First Publication Date 2009-03-12
Grant Date 2011-06-28
Owner
  • Mileutis Ltd. (Israel)
  • State of Israel (Israel)
Inventor
  • Iscovich, Jose Mario
  • Silanikove, Nissim
  • Iscovich, Javier

Abstract

The present invention relates to peptides derived from casein and their use in the management of lactating animals, particularly to methods for decreasing the length of the dry period of a lactating livestock animal, for increasing its milk yield and milk hygiene after parturition and for improving the livestock welfare. The present invention further relates to pharmaceutical compositions comprising peptides derived from casein in the form of a sterile solution, which compositions are clear and substantially devoid of micelles.

IPC Classes  ?

  • A61K 38/00 - Medicinal preparations containing peptides
  • A61P 3/02 - Nutrients, e.g. vitamins, minerals
  • C07K 2/00 - Peptides of undefined number of amino acidsDerivatives thereof

25.

LIVESTOCK MANAGEMENT FOR IMPROVED REPRODUCTIVE EFFICIENCY

      
Application Number IL2007000469
Publication Number 2007/116410
Status In Force
Filing Date 2007-04-11
Publication Date 2007-10-18
Owner
  • MILEUTIS LTD. (Israel)
  • STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (Israel)
Inventor Iscovich, Jose Mario

Abstract

The present invention relates to methods for controlling the reproductive cycles and weaning in livestock, particularly to the use of casein-derived peptides for estrus induction and reduction of anestrus intervals, enabling early weaning without negatively affecting the livestock welfare. The present invention further relates to estrus synchronization in a livestock herd and to livestock management programs.

IPC Classes  ?

  • A23J 1/20 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from milk, e.g. caseinObtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from whey
  • A23J 3/10 - Casein
  • A23J 1/22 - Drying casein
  • A61K 38/00 - Medicinal preparations containing peptides