Goods & Services

Biological assays for research purposes; biological kits comprising arrays and reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising arrays for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use Biological medical and veterinary assays for medical and diagnostic testing purposes; biological kits comprising arrays for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising arrays and reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for medical and/or veterinary use Multi-well plates that can be used in chemical or biological analysis for scientific, laboratory or medical research use Scientific research and development; research and development in the field of assays for the detection and measurement of biological and chemical analytes in samples taken from cells, organisms, and the environment, and research and development regarding the selection, screening, testing, imaging and diagnostics of said samples; providing biological and biochemical sample testing for others through the performance of assays in the fields of scientific and clinical research

Goods & Services

Feature of downloadable computer software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information; feature of downloadable software for controlling the operation of biochemical, biological and chemical analyzers; feature of downloadable software for designing and executing scientific, biological, biochemical and chemical testing and experiments; feature of recorded computer software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information; feature of recorded software for controlling the operation of biochemical, biological and chemical analyzers; feature of recorded software for designing and executing scientific, biological, biochemical and chemical testing and experiments; feature of downloadable and recorded computer software for data management and analysis of biological assays, pharmaceutical screenings, and biological and pharmaceutical testing; feature of downloadable and recorded computer software for data management and analysis of imaging and biological diagnostics; feature of downloadable and recorded computer software allowing administrators and supervisors to assign roles and grant permission to designated users to utilize certain data and information, and perform assigned tasks, associated with scientific, biological, biochemical and chemical research and analysis Providing a website featuring temporary use of non-downloadable software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information; providing a website featuring temporary use of non-downloadable software for performing the assignment of roles, granting of permissions, and designating users to utilize certain data and information, and perform assigned tasks; providing a website featuring temporary use of non-downloadable computer software for data management and analysis of biological assays, pharmaceutical screenings, and biological and pharmaceutical testing; providing a website featuring temporary use of non-downloadable computer software for data management and analysis of imaging and biological diagnostics, controlling the operation of biochemical, biological and chemical analyzers, and designing and executing scientific, biological, biochemical and chemical testing and experiments; providing a website featuring temporary use of a feature of non-downloadable software used for allowing administrators and supervisors to assign roles and grant permission to designated users to utilize certain data and information, and perform assigned tasks, associated with scientific, biological, biochemical and chemical research and analysis

Abstract

Systems and methods for calibrating sample assays are provided. Systems may include assay devices and components for carrying out calibration and sample assays. Systems may further include processing components and storage units configured for receiving calibration information, determining calibration models and parameters, and applying calibration parameters to sample data. Systems may further include components for operating in a networked environment. Methods may include techniques and processes for carrying out calibration and sample assays, determining calibration models and parameters, and applying calibration parameters to sample data.

IPC Classes  ?

• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• G06F 17/18 - Complex mathematical operations for evaluating statistical data

Goods & Services

Biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific, and research use; reagents for scientific use. Reagents for medical research use; Diagnostic reagents for medicinal and veterinary use; Biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and veterinary use. Laboratory consumable, namely, plates having multiple wells that can be used in chemical or biological analysis for scientific, laboratory, or medical research use; laboratory consumable, namely, plates having multi-well arrays that can be used in chemical or biological analysis for scientific, laboratory, or medical research use. Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; Providing biological and biochemical sample testing services for others for scientific research purposes through the performance of assays in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis, namely, data analysis relating to the detection and measurement of biomarkers in biological and biochemical samples in the fields of scientific and clinical research.

Goods & Services

Biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific, and research use; reagents for scientific use. Reagents for medical research use; Diagnostic reagents for medicinal and veterinary use; Biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and veterinary use. Laboratory consumable, namely, plates having multiple wells that can be used in chemical or biological analysis for scientific, laboratory, or medical research use; laboratory consumable, namely, plates having multi-well arrays that can be used in chemical or biological analysis for scientific, laboratory, or medical research use. Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; Providing biological and biochemical sample testing services for others for scientific research purposes through the performance of assays in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis, namely, data analysis relating to the detection and measurement of biomarkers in biological and biochemical samples in the fields of scientific and clinical research.

Goods & Services

(1) Biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific, and research use (2) Reagents for scientific and medical research use; Diagnostic reagents for medicinal and veterinary use; Biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and veterinary use (3) Laboratory consumable, namely, plates having multiple wells that can be used in chemical or biological analysis for scientific, laboratory, or medical research use; laboratory consumable, namely, plates having multi-well arrays that can be used in chemical or biological analysis for scientific, laboratory, or medical research use (1) Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; Providing biological and biochemical sample testing services for others for scientific research purposes through the performance of assays in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis, namely, data analysis relating to the detection and measurement of biomarkers in biological and biochemical samples in the fields of scientific and clinical research

Goods & Services

Biological assays for research purposes; biological kits comprising arrays and reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising arrays for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use. Biological medical and veterinary assays for medical and diagnostic testing purposes; biological kits comprising arrays and reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising arrays for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use. Biological, biochemical and chemical analyzers for performing assays, selection, testing, imaging and diagnostics of biological, biochemical and chemical samples; multi-well plates that can be used in chemical or biological analysis for scientific, laboratory or medical research use; cartridges that can be used in chemical or biological analysis for scientific, laboratory or medical research use; laboratory apparatus, namely, lateral flow test assays, strips, and kits used in chemical or biological analysis for scientific, laboratory or medical research use; recorded software for the computing, sensing, recording, and transmitting of data and information in the fields of scientific research and development, research and development in the fields of biological reagents and chemicals in the fields of science, medicine and laboratory research, research and development in the field of assays for the detection and measurement of biological and chemical analytes, biological, chemical, biochemical, environmental sample testing and diagnostics for others in the fields of scientific and clinical research, and monitoring for the presence of biological, chemical, biochemical, and environmental agents in the nature of pollutants, infectious agents, toxic agents, and hazardous agents for scientific research purposes; downloadable software for the computing, sensing, recording, and transmitting of data and information in the fields of scientific research and development, research and development in the fields of biological reagents and chemicals in the fields of science, medicine and laboratory research, research and development in the field of assays for the detection and measurement of biological and chemical analytes, biological, chemical, biochemical, environmental sample testing and diagnostics for others in the fields of scientific and clinical research, and monitoring for the presence of biological, chemical, biochemical, and environmental agents in the nature of pollutants, infectious agents, toxic agents, and hazardous agents for scientific research purposes; scientific apparatuses for the computing, sensing, recording, and transmitting of data and information in the fields of scientific research and development, research and development in the fields of biological reagents and chemicals in the fields of science, medicine and laboratory research, research and development in the field of assays for the detection and measurement of biological and chemical analytes, biological, chemical, biochemical, environmental sample testing and diagnostics for others in the fields of scientific and clinical research, and monitoring for the presence of biological, chemical, biochemical, and environmental agents in the nature of pollutants, infectious agents, toxic agents, and hazardous agents for scientific research purposes; wearable cameras; wearable activity trackers; wearable computers in the nature of smartwatches; wearable computers in the nature of smartglasses; eyewear; sunglasses; recorded software for controlling the operation of biochemical, biological and chemical analyzers; downloadable computer software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information; downloadable software for controlling the operation of biochemical, biological and chemical analyzers; downloadable software for designing and executing scientific, biological, biochemical and chemical testing and experiments; recorded computer software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information; recorded software for designing and executing scientific, biological, biochemical and chemical testing and experiments; downloadable and recorded computer software for data management and analysis of biological assays, pharmaceutical screenings, and biological and pharmaceutical testing; downloadable and recorded computer software for data management and analysis of imaging and biological diagnostics; downloadable and recorded computer software allowing administrators and supervisors to assign roles and grant permission to designated users to utilize certain data and information, and perform assigned tasks, associated with scientific, biological, biochemical and chemical research and analysis. Medical devices; medical instruments. Clothing; footwear; hats; caps. Toys; games. Educational services; entertainment services. Providing a website featuring temporary use of non-downloadable software used for the computing, sensing, recording, and transmitting of data and information (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); research and development in the field of assays for the detection and measurement of biological and chemical analytes in samples taken from cells, organisms, and the environment, and research and development regarding the selection, screening, testing, imaging and diagnostics of said samples; scientific research and development; providing biological, chemical, biochemical, and environmental sample testing and diagnostics for others through the performance of assays in the fields of scientific and clinical research; monitoring for the presence of biological, chemical, biochemical, and environmental agents in the nature of pollutants, infectious agents, toxic agents, and hazardous agents for scientific research purposes; scientific services, namely, epidemiological testing for scientific research, clinical research, and medical research purposes; scientific research consulting in the field of assays for the detection and measurement of analytes in biological, chemical, biochemical, and environmental samples, and scientific research consulting regarding the selection, screening, testing, imaging and diagnostics of said samples; providing a website featuring temporary use of non-downloadable software for performing the assignment of roles, granting of permissions, and designating users to utilize certain data and information, and perform assigned tasks (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); providing a website featuring temporary use of non-downloadable software used for allowing administrators and supervisors to assign roles and grant permission to designated users to utilize certain data and information, and perform assigned tasks, associated with scientific, biological, biochemical and chemical research and analysis (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); providing a website featuring temporary use of non-downloadable software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); providing a website featuring temporary use of non-downloadable computer software for data management and analysis of biological assays, pharmaceutical screenings, and biological and pharmaceutical testing (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); providing a website featuring temporary use of non-downloadable computer software for data management and analysis of imaging and biological diagnostics, controlling the operation of biochemical, biological and chemical analyzers, and designing and executing scientific, biological, biochemical and chemical testing and experiments (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations).

Abstract

The application is directed to a device housing. The device housing includes a first light device, the first light device including a first electrical supply configured to provide an electrical signal to a first light emitting diode (LED), the first LED separated from a first surface of a diffuser film by a space, wherein the diffuser film includes a second surface, opposite the first surface, the second surface configured to contact a first light pipe.

IPC Classes  ?

• F21V 8/00 - Use of light guides, e.g. fibre optic devices, in lighting devices or systems
• F21V 3/00 - GlobesBowlsCover glasses
• F21Y 113/10 - Combination of light sources of different colours
• F21Y 115/10 - Light-emitting diodes [LED]
• G08B 5/36 - Visible signalling systems, e.g. personal calling systems, remote indication of seats occupied using electric transmissionVisible signalling systems, e.g. personal calling systems, remote indication of seats occupied using electromagnetic transmission using visible light sources

Abstract

The present invention relates to methods, devices and systems for associating assay information with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system includes a reader adapted to read/erase/write information from/to an assay consumable identifier associated with the assay consumable. Various types of assay information are described, as well as methods of using such information in the conduct of an assay by an assay system.

IPC Classes  ?

• G01N 37/00 - Details not covered by any other group of this subclass

Abstract

The present invention relates to methods, devices and systems for associating consumable data with an assay consum- able used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are de- scribed, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instru- ments, systems, and methods, for performing automated biological assays.

IPC Classes  ?

• G01N 21/66 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
• G01N 21/76 - ChemiluminescenceBioluminescence
• G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
• G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
• G01N 37/00 - Details not covered by any other group of this subclass

Abstract

The disclosure relates to methods, compositions, and kits for detecting and analyzing surface marker displaying agents (SMDAs). The disclosure further relates to methods for detecting, diagnosing, monitoring response to treatment or recurrence, or predicting overall survival, progression-free survival or duration of response in a subject suspected of having colorectal cancer (CRC) comprising performing one or more assays on at least one biological sample from the subject to detect one or more specific populations of EVs.

IPC Classes  ?

• C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
• C12Q 1/6834 - Enzymatic or biochemical coupling of nucleic acids to a solid phase
• C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

Abstract

The disclosure relates to methods and kits for detecting, quantifying, or both, phosphorylated tau (p-tau) in a biological sample. The disclosure further provides methods for detecting brain-associated tau polypeptide, a brain injury or a neurodegenerative disease in a subject, determining the eligibility of individuals for participation in clinical trials for brain injury and/or neurodegenerative disease treatments, distinguishing between individuals with brain injury and/or neurodegenerative disease and without brain injury and/or neurodegenerative disease, and monitoring response to treatment of the same.

IPC Classes  ?

• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

Electrochemical cells and methods for their production are provided. In particular, multi-well assay plates including multi-electrode wells are provided. The multi-electrode wells contain multiple electrodes that are electrically isolated from one another, permitting the various electrodes of the various wells to be addressed in any suitable combination.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• G01N 27/327 - Biochemical electrodes
• G01N 27/403 - Cells and electrode assemblies
• G01N 27/49 - Systems involving the determination of the current at a single specific value, or small range of values, of applied voltage for producing selective measurement of one or more particular ionic species

Abstract

The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

IPC Classes  ?

• G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• B01L 9/00 - Supporting devicesHolding devices
• F24F 11/30 - Control or safety arrangements for purposes related to the operation of the system, e.g. for safety or monitoring
• G06K 7/14 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation using light without selection of wavelength, e.g. sensing reflected white light
• G06Q 10/087 - Inventory or stock management, e.g. order filling, procurement or balancing against orders
• G06Q 10/10 - Office automationTime management
• G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
• G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
• G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
• H04B 1/3827 - Portable transceivers

Goods & Services

Reagents for scientific use; biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and research use; biological kits comprising arrays for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and research use; biological kits comprising reagents and arrays for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and research use. Reagents for medical use; reagents for veterinary use; medical and biological diagnostic assays for testing biological samples for medical or veterinary use; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for medical use; biological kits comprising arrays for the detection of biological analytes and for use in the fields of biological and diagnostic testing for medical use; biological kits comprising reagents and arrays for the detection of biological analytes and for use in the fields of biological and diagnostic testing for medical use. Multi-well plates, namely, plates having multi-well arrays, that can be used in chemical or biological analysis for scientific, laboratory or medical research use; biological, biochemical and chemical analyzers for performing assays, selection, testing, and imaging of biological, biochemical, chemical, and environmental samples.

Goods & Services

Biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific, and research use Reagents for scientific and medical research use; Diagnostic reagents for medicinal and veterinary use; Biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and veterinary use Laboratory consumable, namely, plates having multiple wells that can be used in chemical or biological analysis for scientific, laboratory, or medical research use; laboratory consumable, namely, plates having multi-well arrays that can be used in chemical or biological analysis for scientific, laboratory, or medical research use Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; Providing biological and biochemical sample testing services for others for scientific research purposes through the performance of assays in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis, namely, data analysis relating to the detection and measurement of biomarkers in biological and biochemical samples in the fields of scientific and clinical research

Goods & Services

Biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific, and research use Reagents for scientific and medical research use; Diagnostic reagents for medicinal and veterinary use; Biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and veterinary use Laboratory consumable, namely, plates having multiple wells that can be used in chemical or biological analysis for scientific, laboratory, or medical research use; laboratory consumable, namely, plates having multi-well arrays that can be used in chemical or biological analysis for scientific, laboratory, or medical research use Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; Providing biological and biochemical sample testing services for others for scientific research purposes through the performance of assays in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis, namely, data analysis relating to the detection and measurement of biomarkers in biological and biochemical samples in the fields of scientific and clinical research

Goods & Services

Biological assays for research purposes; kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; reagents for scientific and medical research use. Diagnostic reagents for medicinal and veterinary use; biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use. Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; sample testing services in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis.

Abstract

The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
• G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses

Abstract

The present disclosure relates to a method of detecting a nucleic acid analyte, the method comprising contacting an electrode surface comprising a plurality of capture oligonucleotides immobilized on the electrode surface with a solution comprising: a plurality of nucleic acid analytes; and a plurality of detection oligonucleotides, wherein each of the plurality of detection oligonucleotides comprises a first portion and a second portion adjacent to each other, wherein the first portion comprises a sequence that is complementary to a sequence in the capture oligonucleotide and the second portion comprises a sequence that is complementary to a sequence in the nucleic acid analyte.

IPC Classes  ?

• C12Q 1/6825 - Nucleic acid detection involving sensors
• C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
• C12Q 1/6855 - Ligating adaptors

Abstract

The present disclosure relates to a method of detecting a nucleic acid analyte, the method comprising contacting an electrode surface comprising a plurality of capture oligonucleotides immobilized on the electrode surface with a solution comprising: a plurality of nucleic acid analytes; and a plurality of detection oligonucleotides, wherein each of the plurality of detection oligonucleotides comprises a first portion and a second portion adjacent to each other, wherein the first portion comprises a sequence that is complementary to a sequence in the capture oligonucleotide and the second portion comprises a sequence that is complementary to a sequence in the nucleic acid analyte.

IPC Classes  ?

• C12Q 1/6816 - Hybridisation assays characterised by the detection means
• C12Q 1/6825 - Nucleic acid detection involving sensors

Goods & Services

Biological assays for research purposes; kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific, and research use; reagents for scientific and medical research use. Diagnostic reagents for medicinal and veterinary use; biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and veterinary use (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations). Laboratory consumable, namely, plates having multiple wells that can be used in chemical or biological analysis for scientific, laboratory, or medical research use. Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; sample testing services in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis.

Goods & Services

Biological assays for research purposes; kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; reagents for scientific and medical research use. Diagnostic reagents for medicinal and veterinary use; biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations). Multi-well plates that can be used in chemical or biological analysis for scientific, laboratory or medical research use. Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; sample testing services in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis.

Goods & Services

Biological assays for research purposes; kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; reagents for scientific and medical research use. Diagnostic reagents for medicinal and veterinary use; biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations). Multi-well plates that can be used in chemical or biological analysis for scientific, laboratory or medical research use. Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; sample testing services in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis.

Goods & Services

Biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific, and research use; Reagents for scientific and medical research use Diagnostic reagents for medicinal and veterinary use; Biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and veterinary use Laboratory consumable, namely, plates having multiple wells that can be used in chemical or biological analysis for scientific, laboratory, or medical research use; laboratory consumable, namely, plates having multi-well arrays that can be used in chemical or biological analysis for scientific, laboratory, or medical research use Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; Providing biological and biochemical sample testing services for others for scientific research purposes through the performance of assays in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis, namely, data analysis relating to the detection and measurement of biomarkers in biological and biochemical samples in the fields of scientific and clinical research

Goods & Services

(1) Biological assays for research purposes; kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; reagents for scientific and medical research use. (2) Diagnostic reagents for medicinal and veterinary use; biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use. (1) Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; sample testing services in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis.

Goods & Services

(1) Reagents for scientific use; biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and research use; biological kits comprising arrays for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and research use; biological kits comprising reagents and arrays for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and research use. (2) Reagents for medical use; reagents for veterinary use; medical and biological diagnostic assays for testing biological samples for medical or veterinary use; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for medical use; biological kits comprising arrays for the detection of biological analytes and for use in the fields of biological and diagnostic testing for medical use; biological kits comprising reagents and arrays for the detection of biological analytes and for use in the fields of biological and diagnostic testing for medical use. (3) Multi-well plates, namely, plates having multi-well arrays, that can be used in chemical or biological analysis for scientific, laboratory or medical research use; biological, biochemical and chemical analyzers for performing assays, selection, testing, and imaging of biological, biochemical, chemical, and environmental samples.

Goods & Services

Biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific, and research use Reagents for scientific and medical research use; Diagnostic reagents for medicinal and veterinary use; Biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and veterinary use Laboratory consumable, namely, plates having multiple wells that can be used in chemical or biological analysis for scientific, laboratory, or medical research use; laboratory consumable, namely, plates having multi-well arrays that can be used in chemical or biological analysis for scientific, laboratory, or medical research use Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; Providing biological and biochemical sample testing services for others for scientific research purposes through the performance of assays in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis, namely, data analysis relating to the detection and measurement of biomarkers in biological and biochemical samples in the fields of scientific and clinical research

Goods & Services

Biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific, and research use; Reagents for scientific and medical research use Diagnostic reagents for medicinal and veterinary use; Biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and veterinary use Laboratory consumable, namely, plates having multiple wells that can be used in chemical or biological analysis for scientific, laboratory, or medical research use; laboratory consumable, namely, plates having multi-well arrays that can be used in chemical or biological analysis for scientific, laboratory, or medical research use Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; Providing biological and biochemical sample testing services for others for scientific research purposes through the performance of assays in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis, namely, data analysis relating to the detection and measurement of biomarkers in biological and biochemical samples in the fields of scientific and clinical research

Goods & Services

Biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific, and research use Reagents for scientific and medical research use; Diagnostic reagents for medicinal and veterinary use; Biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and veterinary use Laboratory consumable, namely, plates having multiple wells that can be used in chemical or biological analysis for scientific, laboratory, or medical research use; laboratory consumable, namely, plates having multi-well arrays that can be used in chemical or biological analysis for scientific, laboratory, or medical research use Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; Providing biological and biochemical sample testing services for others for scientific research purposes through the performance of assays in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis, namely, data analysis relating to the detection and measurement of biomarkers in biological and biochemical samples in the fields of scientific and clinical research

Goods & Services

Biological assays for research purposes; biological kits comprising arrays and reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use Biological medical and veterinary assays for medical and diagnostic testing purposes; biological kits comprising arrays and reagents for detection and measurement of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use Multi-well plates that can be used in chemical or biological analysis for scientific, laboratory or medical research use Research and development in the fields of assays, selection, screening, testing, imaging and diagnostics; providing biological and biochemical sample testing for others through the performance of assays in the fields of scientific and clinical research

Goods & Services

(1) Biological assays for research purposes; biological kits comprising arrays and reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising arrays for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use. (2) Biological medical and veterinary assays for medical and diagnostic testing purposes; biological kits comprising arrays and reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising arrays for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use. (3) Biological, biochemical and chemical analyzers for performing assays, selection, testing, imaging and diagnostics of biological, biochemical and chemical samples; multi-well plates that can be used in chemical or biological analysis for scientific, laboratory or medical research use; cartridges that can be used in chemical or biological analysis for scientific, laboratory or medical research use; laboratory apparatus, namely, lateral flow test assays, strips, and kits used in chemical or biological analysis for scientific, laboratory or medical research use; recorded software for the computing, sensing, recording, and transmitting of data and information in the fields of scientific research and development, research and development in the fields of biological reagents and chemicals in the fields of science, medicine and laboratory research, research and development in the field of assays for the detection and measurement of biological and chemical analytes, biological, chemical, biochemical, environmental sample testing and diagnostics for others in the fields of scientific and clinical research, and monitoring for the presence of biological, chemical, biochemical, and environmental agents in the nature of pollutants, infectious agents, toxic agents, and hazardous agents for scientific research purposes; downloadable software for the computing, sensing, recording, and transmitting of data and information in the fields of scientific research and development, research and development in the fields of biological reagents and chemicals in the fields of science, medicine and laboratory research, research and development in the field of assays for the detection and measurement of biological and chemical analytes, biological, chemical, biochemical, environmental sample testing and diagnostics for others in the fields of scientific and clinical research, and monitoring for the presence of biological, chemical, biochemical, and environmental agents in the nature of pollutants, infectious agents, toxic agents, and hazardous agents for scientific research purposes; scientific apparatuses for the computing, sensing, recording, and transmitting of data and information in the fields of scientific research and development, research and development in the fields of biological reagents and chemicals in the fields of science, medicine and laboratory research, research and development in the field of assays for the detection and measurement of biological and chemical analytes, biological, chemical, biochemical, environmental sample testing and diagnostics for others in the fields of scientific and clinical research, and monitoring for the presence of biological, chemical, biochemical, and environmental agents in the nature of pollutants, infectious agents, toxic agents, and hazardous agents for scientific research purposes; wearable cameras; wearable activity trackers; wearable computers in the nature of smartwatches; wearable computers in the nature of smartglasses; eyewear; sunglasses; recorded software for controlling the operation of biochemical, biological and chemical analyzers; downloadable computer software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information; downloadable software for controlling the operation of biochemical, biological and chemical analyzers; downloadable software for designing and executing scientific, biological, biochemical and chemical testing and experiments; recorded computer software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information; recorded software for designing and executing scientific, biological, biochemical and chemical testing and experiments; downloadable and recorded computer software for data management and analysis of biological assays, pharmaceutical screenings, and biological and pharmaceutical testing; downloadable and recorded computer software for data management and analysis of imaging and biological diagnostics; downloadable and recorded computer software allowing administrators and supervisors to assign roles and grant permission to designated users to utilize certain data and information, and perform assigned tasks, associated with scientific, biological, biochemical and chemical research and analysis. (4) Medical devices; medical instruments. (5) Clothing; footwear; hats; caps. (6) Toys; games. (1) Educational services; entertainment services. (2) Providing a website featuring temporary use of non-downloadable software used for the computing, sensing, recording, and transmitting of data and information (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); research and development in the field of assays for the detection and measurement of biological and chemical analytes in samples taken from cells, organisms, and the environment, and research and development regarding the selection, screening, testing, imaging and diagnostics of said samples; scientific research and development; providing biological, chemical, biochemical, and environmental sample testing and diagnostics for others through the performance of assays in the fields of scientific and clinical research; monitoring for the presence of biological, chemical, biochemical, and environmental agents in the nature of pollutants, infectious agents, toxic agents, and hazardous agents for scientific research purposes; scientific services, namely, epidemiological testing for scientific research, clinical research, and medical research purposes; scientific research consulting in the field of assays for the detection and measurement of analytes in biological, chemical, biochemical, and environmental samples, and scientific research consulting regarding the selection, screening, testing, imaging and diagnostics of said samples; providing a website featuring temporary use of non-downloadable software for performing the assignment of roles, granting of permissions, and designating users to utilize certain data and information, and perform assigned tasks (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); providing a website featuring temporary use of non-downloadable software used for allowing administrators and supervisors to assign roles and grant permission to designated users to utilize certain data and information, and perform assigned tasks, associated with scientific, biological, biochemical and chemical research and analysis (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); providing a website featuring temporary use of non-downloadable software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); providing a website featuring temporary use of non-downloadable computer software for data management and analysis of biological assays, pharmaceutical screenings, and biological and pharmaceutical testing (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); providing a website featuring temporary use of non-downloadable computer software for data management and analysis of imaging and biological diagnostics, controlling the operation of biochemical, biological and chemical analyzers, and designing and executing scientific, biological, biochemical and chemical testing and experiments (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations).

Goods & Services

Reagents for scientific and medical research use; Reagent kits for scientific and medical research use comprising labeled antibodies or label for antibodies, namely, biological reagentsused to detect and measure biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use Diagnostic reagents for medicinal use; Reagent kits for diagnostic medical purposes comprising labeled antibodies or label for antibodies, namely, biological reagents used to detect and measure biological analytes for use in the fields of biological and diagnostic testing for medical and/or veterinary use

Abstract

The disclosure relates to methods and kits for detecting, quantifying, or both, phosphorylated tau (p-tau) in a biological sample. The disclosure further provides methods for detecting brain-associated tau polypeptide, a brain injury or a neurodegenerative disease in a subject, determining the eligibility of individuals for participation in clinical trials for brain injury and/or neurodegenerative disease treatments, distinguishing between individuals with brain injury and/or neurodegenerative disease and without brain injury and/or neurodegenerative disease, and monitoring response to treatment of the same.

IPC Classes  ?

• G01N 33/541 - Double or second antibody
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

The invention relates to kits and components thereof used in the conduct of solid-phase binding assays.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• C12Q 1/6804 - Nucleic acid analysis using immunogens
• C12Q 1/6816 - Hybridisation assays characterised by the detection means
• C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

Devices and methods for determining whether a contact of a liquid dispenser with a liquid based on sound and/or for determining a liquid volume in the liquid dispenser are provided. According to an embodiment, the liquid dispenser includes a sound generator and an acoustic sensor, and at least one of the sound generator or the acoustic sensor is disposed within the dispense chamber portion. According to an embodiment, the liquid dispenser includes a sound generator and an acoustic sensor, and further includes one or more side conduits, where at least one of the sound generator or the acoustic sensor is disposed within a cavity of a respective one of the one or more side conduits, wherein the cavity and a connector of each of the one or more side conduits are free from resonance within a frequency range of the sound sensed by the acoustic sensor.

IPC Classes  ?

• G01N 1/14 - Suction devices, e.g. pumpsEjector devices
• G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
• G01V 1/02 - Generating seismic energy
• G01V 1/16 - Receiving elements for seismic signalsArrangements or adaptations of receiving elements

IPC Classes  ?

• G01J 1/02 - Photometry, e.g. photographic exposure meter Details
• G01N 21/66 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
• G01N 21/76 - ChemiluminescenceBioluminescence
• G02B 13/18 - Optical objectives specially designed for the purposes specified below with lenses having one or more non-spherical faces, e.g. for reducing geometrical aberration
• G02B 27/00 - Optical systems or apparatus not provided for by any of the groups ,
• G03B 17/55 - Details of cameras or camera bodiesAccessories therefor with provision for heating or cooling, e.g. in aircraft
• H05K 7/20 - Modifications to facilitate cooling, ventilating, or heating

IPC Classes  ?

• F21V 5/00 - Refractors for light sources
• F21V 15/01 - Housings, e.g. material or assembling of housing parts
• F21V 23/00 - Arrangement of electric circuit elements in or on lighting devices
• G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light

Goods & Services

reagents and biological reagents for scientific or medical research use; chemicals for use in the fields of science; chemicals for use in medical and laboratory research for use in industry and science reagents and biological reagents, namely, clinical medical reagents automated assay systems comprising analyzers and other scientific equipment and apparatuses used for performing assays, selection, screening, testing, imaging and diagnostics of biological, biochemical, environmental and chemical samples, not for medical purposes; biological, biochemical and chemical analyzers for performing assays, selection, testing, imaging and diagnostics of biological, biochemical and chemical samples; scientific research equipment and scientific apparatus for use in the performance of assays, selection, testing, imaging and diagnostics of biological, biochemical and chemical samples; computer hardware and peripheral devices used to control and operate portable electronic and scientific instruments in a laboratory setting; Wearable cameras; wearable activity trackers; wearable computers in the nature of smartwatches; wearable computers in the nature of smart glasses; eyewear; sunglasses; recorded software for controlling the operation of biochemical, biological and chemical analyzers; downloadable computer software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information; downloadable software for controlling the operation of biochemical, biological and chemical analyzers; downloadable software for designing and executing scientific, biological, biochemical and chemical testing and experiments; recorded computer software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information; recorded software for designing and executing scientific, biological, biochemical and chemical testing and experiments; downloadable and recorded computer software for data management and analysis of biological assays, pharmaceutical screenings, and biological and pharmaceutical testing; downloadable and recorded computer software for data management and analysis of imaging and biological diagnostics; downloadable and recorded computer software allowing administrators and supervisors to assign roles and grant permission to designated users to utilize certain data and information, and perform assigned tasks, associated with scientific, biological, biochemical and chemical research and analysis Medical imaging apparatus; medical radiation apparatus; medical ultrasound apparatus; medical diagnostic instruments for the analysis of body fluids; medical apparatus and instruments for monitoring patient vital signs, heart rate, pulse, blood pressure, respiratory rate, body temperature, oxygen saturation levels; Medical diagnostic apparatus and instruments for detecting, and testing for, cardiovascular diseases and disorders, respiratory diseases and disorders, blood diseases and disorders, hematologic diseases and disorders, infectious diseases, neurological diseases and disorders, cancer, gastrointestinal diseases and disorders, renal diseases and disorders, urinary diseases and disorders, musculoskeletal and bone diseases and disorders, ophthalmology diseases and disorders, endocrinal diseases and disorders, metabolic disease and disorders, reproductive diseases and disorders, prenatal diseases and disorders, genetic diseases and disorders, immunological diseases and disorders, allergies; Medical apparatus and instruments for the treatment of cardiovascular diseases and disorders, respiratory diseases and disorders, neurological diseases and disorders, pain, cancer, oncological diseases and disorders, orthopedic and musculoskeletal conditions and injuries; renal and urinary diseases and disorders, wounds, skin disorders and diseases, ophthalmology diseases and disorders, gastrointestinal diseases and disorders, reproductive diseases and disorders, audiologic diseases and disorders, diseases and disorders of the ears, nose, and throat, endocrinal diseases and disorders, metabolic diseases and disorders, mental health and neuropsychopathic diseases and disorders, dental diseases and disorders; Medical apparatus and instruments for body rehabilitation; Electronic stimulation apparatus for nerves, muscles, and skin for physical therapy purposes clothing, namely, socks, pants, shirts, tops, hats, sweatshirts, sweaters, underwear, scarves, gloves, bathing suits, swimwear, pajamas, coats, jackets, vests, shorts, hoodies, pullovers, dresses, skirts, headbands, wristbands, robes; caps being headwear; footwear Infant toys; ride-on toys; wind-up toys; stuffed and plush toys; mechanical toys; inflatable toys; construction toys; water toys; squeeze toys; electronic learning toys; children's multiple activity toys; toy furniture; toy cars; toy vehicles; toy figures; action figures; board games; tabletop games; parlour games; card games; action skill games; arcade games custom manufacture of reagents, and chemicals and chemical products for use in the fields of science, medicine and laboratory research for others Entertainment services, namely, development, creation, production and post-production services of multimedia entertainment content; entertainment services in the nature of live musical performances; entertainment media production services for motion pictures, television, and the Internet, entertainment services in the nature of recording, production, and post-production services in the field of music; entertainment services in the nature of creation, development, and production of television programming; Multimedia entertainment services in the nature of development, production and post-production services in the fields of video and films; Entertainment services in the nature of development, creation, production, distribution, and post-production of television shows; Entertainment services in the nature of development, creation, production, distribution, and post-production of motion pictures; Entertainment services, namely, providing temporary use of non-downloadable electronic games, interactive games and non-downloadable video games; Entertainment services, namely, providing podcasts in the field of science and science fiction; Entertainment services, namely, an ongoing multimedia program featuring science, science fiction, drama, comedy, romance, fantasy distributed via various platforms across multiple forms of transmission media; Educational services, namely, providing classes, seminars, workshops, and training courses of instruction in the fields of science, medicine, laboratory and scientific research, and the use of and scientific and medical laboratory technology instruments and apparatus; Educational services, namely, providing webinars and e-learning programs in the fields of science, medicine, laboratory and scientific research, and the use of and scientific and medical laboratory instruments and apparatus; Providing training services in the fields of science, medicine, laboratory and scientific research, and the use of scientific and medical laboratory instruments and apparatus; Providing training for certification in the fields of science, medicine, laboratory and scientific research, and the use of scientific and medical laboratory instruments and apparatus scientific research and development; research and development in the fields of biological reagents and chemicals for use in the fields of science, medicine and laboratory research; providing a website featuring temporary use of non-downloadable software for performing the assignment of roles, granting of permissions, and designating users to utilize certain data and information, and perform assigned tasks; providing a website featuring temporary use of non-downloadable software used for allowing administrators and supervisors to assign roles and grant permission to designated users to utilize certain data and information, and perform assigned tasks, associated with scientific, biological, biochemical and chemical research and analysis; providing a website featuring temporary use of non-downloadable software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information; providing a website featuring temporary use of non-downloadable computer software for data management and analysis of biological assays, pharmaceutical screenings, and biological and pharmaceutical testing; providing a website featuring temporary use of non-downloadable computer software for data management and analysis of imaging and biological diagnostics, controlling the operation of biochemical, biological and chemical analyzers, and designing and executing scientific, biological, biochemical and chemical testing and experiments

Abstract

The invention relates to methods and kits for determining a SARS-CoV-2 strain in a sample. The invention also provides methods and kits for detecting a single nucleotide polymorphism (SNP) in a target nucleic acid, wherein the target nucleic acid is a SARS-CoV-2 nucleic acid. The invention further provides methods and kits for detecting one or more antibody biomarkers in a sample.

IPC Classes  ?

• G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances

Abstract

The present invention is directed to methods for improving assay specificity and performance in binding assays.

IPC Classes  ?

• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• C12Q 1/6832 - Enhancement of hybridisation reaction
• C12Q 1/6837 - Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
• C12Q 1/6844 - Nucleic acid amplification reactions

Abstract

The disclosure relates to method and kits for highly specific detection and quantification of extracellular vesicles (EVs) by targeting at least two EV surface markers using binding reagents. The binding reagents contain hybridisation sequences and primer binding regions, the hybridisation sequences are ligated and amplified using primers. The disclosure further relates to methods and kits for isolating EVs using capture entities, splint entities and staple entities wherein the capture entity comprises a labile linkage.

IPC Classes  ?

• C12Q 1/6816 - Hybridisation assays characterised by the detection means
• C12Q 1/6855 - Ligating adaptors
• C12Q 1/6869 - Methods for sequencing
• C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes

Abstract

The invention relates to novel compositions comprising an electrochemiluminescence (ECL) co-reactant. In embodiments, the composition further comprises an ionic component, a surfactant, or combination thereof. In embodiments, the ECL co-reactant is triethanolamine (TEA), tert-butyldiethanolamine (tBDEA), methyldiethanolamine (MDEA), 3-[Bis-(2-hydroxy-ethyl)-amino]-propane-1-sulfonic acid (DEA-PS), or a combination thereof. Methods of using the compositions and kits comprising the compositions are also provided herein.

IPC Classes  ?

• G01N 21/76 - ChemiluminescenceBioluminescence
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances

IPC Classes  ?

• C12Q 1/6813 - Hybridisation assays
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

IPC Classes  ?

• G01N 21/66 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
• G01N 21/76 - ChemiluminescenceBioluminescence
• H04N 25/71 - Charge-coupled device [CCD] sensorsCharge-transfer registers specially adapted for CCD sensors

Abstract

The invention relates to methods for conducting binding assays in an assay device that includes one or more storage and use zone. The storage zones of the assay device are configured to house one or more reagents used in an assay conducted in the use zone of the device.

IPC Classes  ?

• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• C12Q 1/6823 - Release of bound markers
• C12Q 1/6832 - Enhancement of hybridisation reaction
• C12Q 1/6834 - Enzymatic or biochemical coupling of nucleic acids to a solid phase
• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor

Abstract

The present invention is directed to methods for reducing cross-reactivity between species employed in multiplexed immunoassays.

IPC Classes  ?

• C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
• C12Q 1/6813 - Hybridisation assays
• C12Q 1/6834 - Enzymatic or biochemical coupling of nucleic acids to a solid phase
• G01N 33/542 - ImmunoassayBiospecific binding assayMaterials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals

Abstract

The present invention relates to assays, methods, and kits to assess traumatic brain injury (TBI) in a subject. The present invention also relates to ultrasensitive assays for GFAP, tau, CKBB, IL-1β, IL-2, IL-6, IL-10, IL-22, IP-10, TNFα, TSLP, NFL, and/or NFH.

IPC Classes  ?

• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
• G01N 21/66 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
• G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations

Goods & Services

Biological assays for research purposes; kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use Reagents for scientific and medical research use; Diagnostic reagents for medicinal and veterinary use; Biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use Multi-well plates that can be used in chemical or biological analysis for scientific, laboratory or medical research use Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; sample testing services in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis

Abstract

A sample collection device having a sample container, a solid phase binding material, and a container sealing component is presented. The sample container may have a housing that forms an opening for receiving a sample, and that encloses a space for holding the sample. The solid phase binding material may be disposed within the space enclosed by the housing of the sample container and may be adapted, when the sample contains an analyte, to bind specifically to the analyte. The container sealing component may be removably attachable to the sample container at the opening thereof, and may be adapted, when attached to the sample container, to form a seal around the opening of the sample container.

IPC Classes  ?

• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
• G01N 1/40 - Concentrating samples
• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• B01D 15/38 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups , e.g. affinity, ligand exchange or chiral chromatography
• C12N 5/0781 - B cellsProgenitors thereof
• C12N 5/0783 - T cellsNK cellsProgenitors of T or NK cells

Goods & Services

Biological assays for research purposes; biological kits comprising arrays and reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising arrays for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use Biological medical and veterinary assays for medical and diagnostic testing purposes; biological kits comprising arrays for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising arrays and reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for medical and/or veterinary use Research and development in the fields of biological and chemical assays, and their uses in selection, screening, testing, imaging and diagnostics; providing biological and biochemical sample testing for others through the performance of assays in the fields of scientific and clinical research

Abstract

We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.

IPC Classes  ?

• G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• B67B 7/00 - Hand- or power-operated devices for opening closed containers
• G01N 21/25 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
• G01N 21/64 - FluorescencePhosphorescence
• G01N 21/66 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
• G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
• G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
• G01N 35/04 - Details of the conveyor system
• G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices

Goods & Services

(1) Biological assays for research purposes; kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; reagents for scientific and medical research use. (2) Diagnostic reagents for medicinal and veterinary use; biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations). (3) Multi-well plates that can be used in chemical or biological analysis for scientific, laboratory or medical research use. (1) Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; sample testing services in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis.

Goods & Services

(1) Biological assays for research purposes; kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; reagents for scientific and medical research use. (2) Diagnostic reagents for medicinal and veterinary use; biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations). (3) Multi-well plates that can be used in chemical or biological analysis for scientific, laboratory or medical research use. (1) Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; sample testing services in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis.

Goods & Services

(1) Biological assays for research purposes; kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific, and research use; reagents for scientific and medical research use. (2) Diagnostic reagents for medicinal and veterinary use; biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and veterinary use (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations). (3) Laboratory consumable, namely, plates having multiple wells that can be used in chemical or biological analysis for scientific, laboratory, or medical research use. (1) Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; sample testing services in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis.

Abstract

The disclosure relates to methods and kits for detecting tau, e.g., tau that is phosphorylated at amino acid position T181 (pTau181), tau that is phosphorylated at amino acid position T217 (pTau217), and/or total tau. The disclosure further provides methods for distinguishing between individuals whose cognitive condition will remain stable and whose cognitive condition will decline during their lifetime. The disclosure also provides methods for determining the eligibility of individuals for participation in clinical trials for Alzheimer's disease treatments. Also provided are methods for distinguishing between individuals with Alzheimer's disease and non-Alzheimer's dementia, and for monitoring response to treatment for Alzheimer's disease.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• C12Q 1/6844 - Nucleic acid amplification reactions
• G01N 21/76 - ChemiluminescenceBioluminescence

Abstract

Described herein is a method for detecting an oligonucleotide in a sample, and in particular, to a method for detecting sense and antisense strands of an oligonucleotide duplex in a sample.

IPC Classes  ?

• C12Q 1/6816 - Hybridisation assays characterised by the detection means

Abstract

Described herein is a method for detecting an oligonucleotide in a sample, and in particular, to a method for detecting sense and antisense strands of an oligonucleotide duplex in a sample.

IPC Classes  ?

• C12Q 1/6834 - Enzymatic or biochemical coupling of nucleic acids to a solid phase
• C12Q 1/44 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase involving esterase
• C12Q 1/6818 - Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer

Abstract

The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
• G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses

Goods & Services

Reagents for scientific use; Biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and research use; biological kits comprising arrays for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and research use; biological kits comprising reagents and arrays for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and research use Reagents for medical use; reagents for veterinary use; medical and biological diagnostic assays for testing biological samples for medical or veterinary use; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for medical use; biological kits comprising arrays for the detection of biological analytes and for use in the fields of biological and diagnostic testing for medical use; biological kits comprising reagents and arrays for the detection of biological analytes and for use in the fields of biological and diagnostic testing for medical use Multi-well plates, namely, plates having multi-well arrays, that can be used in chemical or biological analysis for scientific, laboratory or medical research use; biological, biochemical and chemical analyzers, namely, electronic analyzers for testing and analyzing chemical and biological substances for the presence, absence, or quantity of target chemicals for performing assays, selection, testing, and imaging of biological, biochemical, chemical, and environmental samples

Goods & Services

Biological assays for research purposes; kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; Reagents for scientific and medical research use Diagnostic reagents for medicinal and veterinary use; Biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; Providing biological and biochemical sample testing services for others for scientific research purposes through the performance of assays in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis

Goods & Services

Research and development in the field of biology, chemistry, biochemistry, microbiology, and genetics; scientific research and development.

Goods & Services

Biological assays for research purposes; biological kits comprising arrays and reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising arrays for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use. Biological medical and veterinary assays for medical and diagnostic testing purposes; biological kits comprising arrays and reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising arrays for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use. Multi-well plates that can be used in chemical or biological analysis for scientific, laboratory or medical research use; cartridges for use in chemical or biological analysis for scientific, laboratory or medical research use.

Goods & Services

biological assays for research purposes; biological kits comprising arrays and reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising arrays for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; Chemically treated non-medical test strips used in chemical or biological analysis for scientific, laboratory or medical research use biological medical and veterinary assays for medical and diagnostic testing purposes; biological kits comprising arrays and reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising arrays for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use biological, biochemical and chemical analyzers for performing assays, selection, testing, imaging and diagnostics of biological, biochemical and chemical samples; Multi-well plates, namely, plates having multi-well arrays that can be used in chemical analysis and biological analysis for scientific, laboratory or medical research use; cartridges for use in chemical or biological analysis for scientific, laboratory or medical research use; laboratory apparatus, namely, lateral flow test assay devices and kits comprising reagents and reaction vessels; recorded software for the computing, sensing, recording, and transmitting of data and information in the fields of scientific research and development, research and development in the fields of biological reagents and chemicals in the fields of science, medicine and laboratory research, research and development in the field of assays for the detection and measurement of biological and chemical analytes, biological, chemical, biochemical, environmental sample testing and diagnostics for others in the fields of scientific and clinical research, and monitoring for the presence of biological, chemical, biochemical, and environmental agents in the nature of pollutants, infectious agents, toxic agents, and hazardous agents for scientific research purposes; downloadable software for the computing, sensing, recording, and transmitting of data and information in the fields of scientific research and development, research and development in the fields of biological reagents and chemicals in the fields of science, medicine and laboratory research, research and development in the field of assays for the detection and measurement of biological and chemical analytes, biological, chemical, biochemical, environmental sample testing and diagnostics for others in the fields of scientific and clinical research, and monitoring for the presence of biological, chemical, biochemical, and environmental agents in the nature of pollutants, infectious agents, toxic agents, and hazardous agents for scientific research purposes; scientific apparatuses for the computing, sensing, recording, and transmitting of data and information in the fields of scientific research and development, research and development in the fields of biological reagents and chemicals in the fields of science, medicine and laboratory research, research and development in the field of assays for the detection and measurement of biological and chemical analytes, biological, chemical, biochemical, environmental sample testing and diagnostics for others in the fields of scientific and clinical research, and monitoring for the presence of biological, chemical, biochemical, and environmental agents in the nature of pollutants, infectious agents, toxic agents, and hazardous agents for scientific research purposes; wearable cameras; wearable activity trackers; wearable computers in the nature of smartwatches; wearable computers in the nature of smartglasses; eyewear; sunglasses; recorded software for controlling the operation of biochemical, biological and chemical analyzers; downloadable computer software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information; downloadable software for controlling the operation of biochemical, biological and chemical analyzers; downloadable software for designing and executing scientific, biological, biochemical and chemical testing and experiments; recorded computer software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information; recorded software for designing and executing scientific, biological, biochemical and chemical testing and experiments; downloadable and recorded computer software for data management and analysis of biological assays, pharmaceutical screenings, and biological and pharmaceutical testing; downloadable and recorded computer software for data management and analysis of imaging and biological diagnostics; downloadable and recorded computer software allowing administrators and supervisors to assign roles and grant permission to designated users to utilize certain data and information, and perform assigned tasks, associated with scientific, biological, biochemical and chemical research and analysis; Medical laboratory research apparatus and instruments for handling, processing, and preparing biological specimens for diagnostic analysis Medical imaging apparatus; medical radiation apparatus; medical ultrasound apparatus; medical diagnostic instruments for the analysis of body fluids; medical apparatus and instruments for monitoring patient vital signs, heart rate, pulse, blood pressure, respiratory rate, body temperature, oxygen saturation levels; Medical diagnostic apparatus and instruments for detecting, and testing for, cardiovascular diseases and disorders, respiratory diseases and disorders, blood diseases and disorders, hematologic diseases and disorders, infectious diseases, neurological diseases and disorders, cancer, gastrointestinal diseases and disorders, renal diseases and disorders, urinary diseases and disorders, musculoskeletal and bone diseases and disorders, ophthalmology diseases and disorders, endocrinal diseases and disorders, metabolic disease and disorders, reproductive diseases and disorders, prenatal diseases and disorders, genetic diseases and disorders, immunological diseases and disorders, allergies; Medical apparatus and instruments for the treatment of cardiovascular diseases and disorders, respiratory diseases and disorders, neurological diseases and disorders, pain, cancer, oncological diseases and disorders, orthopedic and musculoskeletal conditions and injuries; renal and urinary diseases and disorders, wounds, skin disorders and diseases, ophthalmology diseases and disorders, gastrointestinal diseases and disorders, reproductive diseases and disorders, audiologic diseases and disorders, diseases and disorders of the ears, nose, and throat, endocrinal diseases and disorders, metabolic diseases and disorders, mental health and neuropsychopathic diseases and disorders, dental diseases and disorders; Medical apparatus and instruments for body rehabilitation; Electronic stimulation apparatus for nerves, muscles, and skin for physical therapy purposes clothing, namely, socks, pants, shirts, tops, hats, sweatshirts, sweaters, underwear, scarves, gloves, bathing suits, swimwear, pajamas, coats, jackets, vests, shorts, hoodies, pullovers, dresses, skirts, headbands, wristbands, robes; caps being headwear; footwear Infant toys; ride-on toys; wind-up toys; stuffed and plush toys; mechanical toys; inflatable toys; construction toys; water toys; squeeze toys; electronic learning toys; children's multiple activity toys; toy furniture; toy cars; toy vehicles; toy figures; action figures; board games; tabletop games; parlour games; card games; action skill games; arcade games Entertainment services, namely, development, creation, production and post-production services of multimedia entertainment content; entertainment services in the nature of live musical performances; entertainment media production services for motion pictures, television, and the Internet, entertainment services in the nature of recording, production, and post-production services in the field of music; entertainment services in the nature of creation, development, and production of television programming; Multimedia entertainment services in the nature of development, production and post-production services in the fields of video and films; Entertainment services in the nature of development, creation, production, distribution, and post-production of television shows; Entertainment services in the nature of development, creation, production, distribution, and post-production of motion pictures; Entertainment services, namely, providing temporary use of non-downloadable electronic games, interactive games and non-downloadable video games; Entertainment services, namely, providing podcasts in the field of science and science fiction; Entertainment services, namely, an ongoing multimedia program featuring science, science fiction, drama, comedy, romance, fantasy distributed via various platforms across multiple forms of transmission media; Educational services, namely, providing classes, seminars, workshops, and training courses of instruction in the fields of science, medicine, laboratory and scientific research, and the use of and scientific and medical laboratory technology instruments and apparatus; Educational services, namely, providing webinars and e-learning programs in the fields of science, medicine, laboratory and scientific research, and the use of and scientific and medical laboratory instruments and apparatus; Providing training services in the fields of science, medicine, laboratory and scientific research, and the use of scientific and medical laboratory instruments and apparatus; Providing training for certification in the fields of science, medicine, laboratory and scientific research, and the use of scientific and medical laboratory instruments and apparatus providing a website featuring temporary use of non-downloadable software used for the computing, sensing, recording, and transmitting of data and information; Research and development in the field of assays for the detection and measurement of biological and chemical analytes in samples taken from cells, organisms, and the environment, and research and development regarding the selection, screening, testing, imaging and diagnostics of said samples; scientific research and development; providing biological, chemical, biochemical, and environmental sample testing and diagnostics for others through the performance of assays in the fields of scientific and clinical research; monitoring for the presence of biological, chemical, biochemical, and environmental agents in the nature of pollutants, infectious agents, toxic agents, and hazardous agents for scientific research purposes; scientific services, namely, epidemiological testing for scientific research, clinical research, and medical research purposes; scientific research consulting in the field of assays for the detection and measurement of analytes in biological, chemical, biochemical, and environmental samples, and scientific research consulting regarding the selection, screening, testing, imaging and diagnostics of said samples; providing a website featuring temporary use of non-downloadable software for performing the assignment of roles, granting of permissions, and designating users to utilize certain data and information, and perform assigned tasks; providing a website featuring temporary use of non-downloadable software used for allowing administrators and supervisors to assign roles and grant permission to designated users to utilize certain data and information, and perform assigned tasks, associated with scientific, biological, biochemical and chemical research and analysis; providing a website featuring temporary use of non-downloadable software for the collection, editing, organizing, modifying, transmission, storage and sharing of data and information; providing a website featuring temporary use of non-downloadable computer software for data management and analysis of biological assays, pharmaceutical screenings, and biological and pharmaceutical testing; providing a website featuring temporary use of non-downloadable computer software for data management and analysis of imaging and biological diagnostics, controlling the operation of biochemical, biological and chemical analyzers, and designing and executing scientific, biological, biochemical and chemical testing and experiments

Goods & Services

Automated assay systems comprising analyzers and other scientific equipment and apparatuses used for performing assays, selection, screening, testing, imaging and diagnostics of biological, biochemical, environmental and chemical samples. Providing biological, chemical, biochemical, and environmental sample testing and diagnostics for others through the performance of assays in the fields of scientific and clinical research; monitoring for the presence of biological, chemical, biochemical, and environmental agents in the nature of pollutants, infectious agents, toxic agents, and hazardous agents for scientific research purposes; scientific services, namely, epidemiological testing for scientific research, clinical research, and medical research purposes; scientific research consulting in the field of assays for the detection and measurement of analytes in biological, chemical, biochemical, and environmental samples, and scientific research consulting regarding the selection, screening, testing, imaging and diagnostics of said samples.

Abstract

Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.

IPC Classes  ?

• G02B 7/36 - Systems for automatic generation of focusing signals using image sharpness techniques
• G01N 21/25 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
• G01N 21/64 - FluorescencePhosphorescence
• G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations

Goods & Services

(1) Biological assays for research purposes; biological kits comprising arrays and reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising arrays for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use. (2) Biological medical and veterinary assays for medical and diagnostic testing purposes; biological kits comprising arrays and reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising arrays for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use. (3) Multi-well plates that can be used in chemical or biological analysis for scientific, laboratory or medical research use; cartridges for use in chemical or biological analysis for scientific, laboratory or medical research use.

Goods & Services

Biological, biochemical and chemical electrochemiluminescence-based analyzers for performing assays, selection, screening, testing, imaging and diagnostics of biological, biochemical, environmental and chemical samples; all of the forgoing excluding mass spectrometers, mass selective detectors, detectors for use with chromatographs, and goods or services for use with mass spectrometers, mass selective detectors and detectors for use with chromatographs (term considered linguistically incorrect by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations).

Goods & Services

(1) Research and development in the field of biology, chemistry, biochemistry, microbiology, and genetics; scientific research and development.

Goods & Services

biological kits comprising arrays and reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising reagents for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; biological kits comprising arrays for detection and measurement of biological analytes for use in the fields of biological and diagnostic testing for industrial, scientific and/or research use; Biological assays for research purposes Biological medical and veterinary assays for medical and diagnostic testing purposes; biological kits comprising arrays and reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising arrays for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and/or veterinary use Multi-well plates that can be used in chemical or biological analysis for scientific, laboratory or medical research use; Cartridges for use in chemical or biological analysis for scientific, laboratory or medical research use Research and development in the fields of assays, selection, screening, testing, imaging and diagnostics using electrochemiluminescence; providing biological and biochemical sample testing for others through the performance of assays in the fields of scientific and clinical research; scientific research and development

Abstract

Systems and methods for improving assay results obtained by silicon photomultiplier devices are provided. Systems may include assay devices including silicon photomultiplier devices and computing systems. Systems may further include processing components and storage units configured for receiving silicon photomultiplier device input and output information and for determining silicon photomultiplier device temperatures.

IPC Classes  ?

• G01J 1/44 - Electric circuits
• G01N 21/64 - FluorescencePhosphorescence
• G01N 21/76 - ChemiluminescenceBioluminescence

Goods & Services

(1) Automated assay systems comprising analyzers and other scientific equipment and apparatuses used for performing assays, selection, screening, testing, imaging and diagnostics of biological, biochemical, environmental and chemical samples. (1) Providing biological, chemical, biochemical, and environmental sample testing and diagnostics for others through the performance of assays in the fields of scientific and clinical research; monitoring for the presence of biological, chemical, biochemical, and environmental agents in the nature of pollutants, infectious agents, toxic agents, and hazardous agents for scientific research purposes; scientific services, namely, epidemiological testing for scientific research, clinical research, and medical research purposes; scientific research consulting in the field of assays for the detection and measurement of analytes in biological, chemical, biochemical, and environmental samples, and scientific research consulting regarding the selection, screening, testing, imaging and diagnostics of said samples.

Abstract

The present disclosure relates to an automated assay system adapted to receive consumables in the conduct of an assay. The assay system includes at least one of a loading cart, a door support system, a waste storage unit, and a robotic subsystem. The loading cart is configured to organize and transport consumables necessary for the performance of the assay system. The door support system is configured to maintain stability of doors of the automated assay system. The waste storage unit is configured to provide convenient disposal of consumables associated with the automated assay system. The robotic subsystem is configured to transport consumables within the automated assay system.

IPC Classes  ?

• G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• B65D 43/02 - Removable lids or covers
• B65D 43/26 - Mechanisms for opening or closing, e.g. pedal- operated
• B65D 51/24 - Closures not otherwise provided for combined with auxiliary devices for non-closing purposes

Abstract

We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.

IPC Classes  ?

• G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations

Abstract

The present disclosure provides compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the disclosure relates to an assay composition for detecting luminescence, which comprises an alkyl diethanolamine, for example, N-butyldiethanolamine (BDEA). In emodiments, the assay composition comprises 2-dibutylaminoethanol (BDAE).

IPC Classes  ?

• G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances
• G01N 21/66 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence

Abstract

The invention relates to methods and kits for determining a SARS-CoV-2 strain in a sample. The invention also provides methods and kits for detecting a single nucleotide polymorphism (SNP) in a target nucleic acid, wherein the target nucleic acid is a SARS-CoV-2 nucleic acid. The invention further provides methods and kits for detecting one or more antibody biomarkers in a sample.

IPC Classes  ?

• G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses

Abstract

Devices and methods for a microplate lid configured to cover a microwell assay plate are provided. A microplate lid includes a lid panel surrounded by a lid frame. Sidewalls extend downwardly from lid frame. The microplate lid includes various features to improve performance, including features to improve stickability, reduce warping, reduce sample contamination, reduce wear, reduce sample evaporation, facilitate robotic handling, and provide other benefits.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers

Goods & Services

Biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific, and research use Reagents for scientific and medical research use; Diagnostic reagents for medicinal and veterinary use; Biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and veterinary use Laboratory consumable, namely, plates having multiple wells that can be used in chemical or biological analysis for scientific, laboratory, or medical research use; laboratory consumable, namely, plates having multi-well arrays that can be used in chemical or biological analysis for scientific, laboratory, or medical research use Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; Providing biological and biochemical sample testing services for others for scientific research purposes through the performance of assays in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis, namely, data analysis relating to the detection and measurement of biomarkers in biological and biochemical samples in the fields of scientific and clinical research

Goods & Services

Biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific and research use; reagents for scientific purposes; reagents for medical research use Diagnostic reagents for medicinal and veterinary use; Biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and veterinary use Multi-well plates that can be used in chemical or biological analysis for scientific, laboratory or medical research use Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; providing biological and biochemical sample testing services through the performance of assays in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis, namely, data analysis relating to the detection and measurement of biomarkers in samples in the fields of scientific and clinical research

Goods & Services

Biological assays for research purposes; biological kits comprising reagents for the detection of biological analytes and for use in the fields of biological and diagnostic testing for industrial, scientific, and research use Reagents for scientific and medical research use; Diagnostic reagents for medicinal and veterinary use; Biological medical and veterinary assays and reagents for medical and diagnostic testing purposes; biological kits comprising reagents for detection of biological analytes and for use in the fields of biological and diagnostic testing for medical and veterinary use Laboratory consumable, namely, plates having multiple wells that can be used in chemical or biological analysis for scientific, laboratory, or medical research use; laboratory consumable, namely, plates having multi-well arrays that can be used in chemical or biological analysis for scientific, laboratory, or medical research use Research and development in the field of assays for the detection and measurement of molecules, proteins, and peptides in biological samples and environmental samples; Providing biological and biochemical sample testing services for others for scientific research purposes through the performance of assays in the fields of scientific and clinical research; laboratory biomarker analysis services and related data analysis, namely, data analysis relating to the detection and measurement of biomarkers in biological and biochemical samples in the fields of scientific and clinical research

Abstract

An electrochemical cell includes a plurality of working electrode zones disposed, and defining a pattern, on a surface of the cell and at least one auxiliary electrode disposed on the surface. The auxiliary electrode having a defined interfacial potential.

IPC Classes  ?

• G01N 27/49 - Systems involving the determination of the current at a single specific value, or small range of values, of applied voltage for producing selective measurement of one or more particular ionic species
• G01N 27/327 - Biochemical electrodes

Abstract

The present invention is directed to methods for improving assay specificity and performance in binding assays.

IPC Classes  ?

• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
• C12Q 1/6804 - Nucleic acid analysis using immunogens
• G01N 21/66 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
• G01N 21/76 - ChemiluminescenceBioluminescence
• G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
• G01N 33/533 - Production of labelled immunochemicals with fluorescent label
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
• G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances

Abstract

The invention relates to a load support unit for holding and adjusting the orientation of the load. The load support unit includes a lower arm, a upper arm, a mounting swivel, a swivel joint, a knuckle joint and a rotational joint. The mounting swivel allows the load support unit to rotate relative to its surroundings, the swivel joint allows the upper arm to rotate relative to the lower arm, the knuckle joint allows the upper arm to pivot in a rotational direction relative to the lower arm, and the rotational joint allows the load to rotate about the upper arm.

IPC Classes  ?

• F16M 11/14 - Means for attachment of apparatusMeans allowing adjustment of the apparatus relatively to the stand allowing pivoting in more than one direction with ball-joint
• F16M 11/20 - Undercarriages with or without wheels
• F16M 13/02 - Other supports for positioning apparatus or articlesMeans for steadying hand-held apparatus or articles for supporting on, or attaching to, an object, e.g. tree, gate, window-frame, cycle
• H04N 5/64 - Constructional details of receivers, e.g. cabinets or dust covers
• F16M 11/04 - Means for attachment of apparatusMeans allowing adjustment of the apparatus relatively to the stand

IPC Classes  ?

• F16M 11/04 - Means for attachment of apparatusMeans allowing adjustment of the apparatus relatively to the stand
• F16M 11/14 - Means for attachment of apparatusMeans allowing adjustment of the apparatus relatively to the stand allowing pivoting in more than one direction with ball-joint
• F16M 11/20 - Undercarriages with or without wheels
• F16M 13/02 - Other supports for positioning apparatus or articlesMeans for steadying hand-held apparatus or articles for supporting on, or attaching to, an object, e.g. tree, gate, window-frame, cycle
• H04N 5/64 - Constructional details of receivers, e.g. cabinets or dust covers

Abstract

The invention relates to a load support unit for holding and adjusting the orientation of the load. The load support unit includes a lower arm, a upper arm, a mounting swivel, a swivel joint, a knuckle joint and a rotational joint. The mounting swivel allows the load support unit to rotate relative to its surroundings, the swivel joint allows the upper arm to rotate relative to the lower arm, the knuckle joint allows the upper arm to pivot in a rotational direction relative to the lower arm, and the rotational joint allows the load to rotate about the upper arm.

IPC Classes  ?

• F16M 13/02 - Other supports for positioning apparatus or articlesMeans for steadying hand-held apparatus or articles for supporting on, or attaching to, an object, e.g. tree, gate, window-frame, cycle
• F16M 11/14 - Means for attachment of apparatusMeans allowing adjustment of the apparatus relatively to the stand allowing pivoting in more than one direction with ball-joint
• F16M 11/20 - Undercarriages with or without wheels

Abstract

The present invention relates to a system for performing assays on a solid phase to measure the level of analyte in a sample. Such a system may perform immunoassays using electrochemiluminescence (ECL) including a counterbalanced orbital shaking apparatus for assay consumables. The counterbalanced orbital shaking apparatus also incubates the assay consumables, and has a cooling system to maintain a preset temperature within the shaking apparatus.

IPC Classes  ?

• G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
• B01L 1/00 - EnclosuresChambers
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
• G01N 35/04 - Details of the conveyor system
• G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices

Abstract

The invention relates to method and kits for highly specific isolation of extracellular vesicles (EVs) by targeting at least two EV surface markers. The invention further relates to methods and kits for analyzing EVs and their contents.

IPC Classes  ?

• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals