Abstract

An apparatus for the extraction of compounds from botanical material using a condensable gas solvent includes an extraction chamber and a cyclonic separator. The cyclonic separator includes a cyclone chamber having a cyclonic tangential fluid inlet. A solvent flow path extends from the extraction chamber to the cyclonic tangential fluid inlet. A sonic flow nozzle is positioned in the solvent flow path upstream of the cyclonic tangential fluid inlet.

IPC Classes  ?

• B01D 11/02 - Solvent extraction of solids
• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A61K 36/185 - Magnoliopsida (dicotyledons)

Abstract

Described are methods for determining a recommended dosage and/or variety of cannabis for a subject based on genetic testing. The presence or absence of genetic variants in a sample from the subject is determined and used to determine a recommended dosage of cannabis, estimate the sensitivity of the subject to cannabis, or select a subject for the treatment of a medical condition. In some embodiments the genetic variants include polymorphisms in or near CYP2C9, CYP3A4 and/or CYP2C19, optionally that are associated with cannabinoid metabolism. The recommended dosage may be for a specific variety of cannabis for treating a medical condition.

IPC Classes  ?

• C12Q 1/6809 - Methods for determination or identification of nucleic acids involving differential detection
• A61K 31/05 - Phenols
• A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
• C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
• C07D 311/80 - DibenzopyransHydrogenated dibenzopyrans
• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
• C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
• G01N 33/48 - Biological material, e.g. blood, urineHaemocytometers

Abstract

An apparatus for the comminution of a botanical feedstock includes a vessel, a screen positioned in the vessel above a first feedstock outlet and spaced from the top of the vessel, and a blade rotatably mounted above and generally parallel to the screen. The blade has a leading side, a trailing side, and a radial blade length. At least a portion of the leading side has a cutting edge and at least a portion of the trailing side has a downwardly extending trailing portion. The downwardly extending trailing portion has a lower edge having a plurality of discontinuities along a radial length of the trailing portion. The cutting edge is spaced from the upper surface of the screen by a first distance and a lowermost portion of the lower edge is spaced from the upper surface of the screen by a second distance.

IPC Classes  ?

• B02C 18/08 - Disintegrating by knives or other cutting or tearing members which chop material into fragmentsMincing machines or similar apparatus using worms or the like with rotating knives within vertical containers
• A24B 7/00 - Cutting tobacco
• B02C 18/18 - KnivesMountings thereof
• B02C 23/10 - Separating or sorting of material, associated with crushing or disintegrating with separator arranged in discharge path of crushing or disintegrating zone
• B02C 23/16 - Separating or sorting of material, associated with crushing or disintegrating with separator defining termination of crushing or disintegrating zone, e.g. screen denying egress of oversize material

Goods & Services

Downloadable electronic publications, namely, newsletters, brochures, reports and guides in the field of cannabis Computer services, namely, creating an online community for registered users to participate in discussions, get feedback from their peers, from virtual communities, and engage in social networking in the field of cannabis