01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Reagents for scientific or medical research use; chemicals
for scientific or laboratory purposes; reagents for
scientific purposes; biological tissue cultures, other than
for medical or veterinary purposes; biological preparations,
other than for medical or veterinary purposes; biological
preparation for use in cell cultures other than for medical
or veterinary use; reagents for medical research. Drug delivery agents; drug delivery agents that facilitate
the delivery of pharmaceutical preparations; bone cement for
surgical and orthopaedic purposes; topical gels for medical
and therapeutic purposes; biological tissue cultures for
medical purposes; biological preparations for medical
purposes; embedding material for dental purposes; materials
for tooth fillings; preparations to facilitate teething;
preparations to develop teething.
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Reagents for scientific or medical research use; chemical preparations for scientific or laboratory purposes; reagents for scientific purposes; biological tissue cultures, other than for medical or veterinary purposes; biological preparations, for use in cell cultures other than for medical or veterinary purposes; biological preparation for use in cell cultures other than for medical or veterinary use; reagents for medical research Drug delivery agents in the form of local injection, transdermal, topical, intradermal dosage, spray, implant that facilitate the delivery of pharmaceutical preparations; drug delivery agents consisting of compounds that facilitate the delivery of pharmaceutical preparations; bone cement for surgical and orthopaedic purposes; topical gels for medical and therapeutic purposes, namely, local hydrogel or sprayable hydrogel improved patient compliance; biological tissue cultures for medical purposes; biological preparations for medical purposes, namely, for the treatment of wound healing, bone defect, spinal cord injury, cell therapy; embedding material in the nature of thermosensitive hydrogel containing polyphosphazene for dental purposes, namely, alveolar bone therapy; materials for tooth fillings; preparations to facilitate teething being teething prophylactics; preparations to develop teething being teething prophylactics
3.
Composition of thermosensitive hydrogels having altered reversible sol-gel transition property, and use thereof
The present invention relates to a thermosensitive hydrogel composition, which while comprising an amino acid ester, polyethylene glycol, and a functional group for the introduction of a functional moiety at an end thereof at a predetermined ratio, comprises a polyphosphazene-based polymer having a controlled length and a content of polyethylene glycol contained therein, in which a reversible sol-gel transition character is altered; a medical polymer hydrogel comprising the polyphosphazene-based polymer; or an ink composition for 3D printing.
B33Y 70/10 - Composites of different types of material, e.g. mixtures of ceramics and polymers or mixtures of metals and biomaterials
B33Y 80/00 - Products made by additive manufacturing
4.
HYDROGEL INCLUSION COMPLEX INCLUDING PHYSIOLOGICALLY ACTIVE MATERIAL BOUND TO THERMOSENSITIVE POLY(PHOSPHAZENE) BY HOST-GUEST INTERACTION USING BETA-CYCLODEXTRIN AND USE THEREOF
Provided is a hydrogel composition including thermosensitive poly(phosphazene) to which a plurality of hydrophobic amino acids, hydrophilic polymers, and host molecules are substituted; and a physiologically active material linked to a guest molecule, wherein the poly(phosphazene) and the physiologically active material form a conjugate by inclusion of the guest molecule in the host molecule via a host-guest interaction.
The present disclosure relates to a pharmaceutical composition for preventing or treating spinal cord injury comprising an imidazole-poly(organophosphazene) hydrogel or a pharmaceutically acceptable salt thereof, a method for preventing or treating spinal cord injury, and a food composition for preventing or ameliorating spinal cord injury.
The imidazole-poly(organophosphazene) hydrogel of the present disclosure has the effect of regenerating the extracellular matrix (ECM) by filling cystic cavities and can thus be effectively used for the prevention and treatment of spinal cord injury by a simple injection method.
Provided is a thermosensitive phosphazene-based polymer including an amino acid ester moiety, a polyethyleneglycol moiety, and a moiety including a sulfate group linked directly or by a linker in a predetermined ratio, a method of preparing the same, and a hydrogel-formable composition including the same. For example, a hydrogel formed from the composition may be used for tissue regeneration or drug delivery or used as a storage, a body tissue regeneration inducer, or a filler in a body.
C08F 30/02 - Homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing phosphorus
A61L 27/16 - Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
A61L 27/36 - Materials for prostheses or for coating prostheses containing ingredients of undetermined constitution or reaction products thereof
The present invention relates to a phosphazene-based polymer comprising an amino acid ester, polyethylene glycol, a group comprising a functional group, and a catechol group linked directly or by a linker to a part of or an entire functional group, in a predetermined ratio. In addition, the present invention relates to a preparation method thereof, and a tissue-adhesive composition comprising the same as an active ingredient.
Provided are a use of chemically-crosslinkable, poly(organophosphazene)s for biomaterials, chemically-crosslinkable poly(organophosphazene)s with a physiologically active substance covalently-bonded thereto, a use thereof for biomaterials, and a process for preparing the same. The chemical crosslinkings can be made by UV irradiation, and/or a crosslinker, and/or an additive, and/or an enzyme, and/or a mixing of at least one polymer.
C12N 9/96 - Stabilising an enzyme by forming an adduct or a compositionForming enzyme conjugates
C08G 69/48 - Polymers modified by chemical after-treatment
C08G 63/91 - Polymers modified by chemical after-treatment
A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
9.
Biodegradable and thermosensitive poly(organophosphazene)-superparamagnetic nanoparticle complex, preparation method and use thereof
2* weighted image, and the poly(organophosphazene) shows a sol-to-gel behavior depending upon the temperature change. The complex is a bound-type where the superparamagnetic ferrite nanoparticle is bonded to phosphazene-based polymer via hydrophobic binding, and a mixed-type where the superparamagnetic ferrite nanoparticle is physically mixed with the phosphazene-based polymer.
B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 49/18 - Nuclear magnetic resonance [NMR] contrast preparationsMagnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
B82Y 15/00 - Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
C08G 79/02 - Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon a linkage containing phosphorus
C08L 85/02 - Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbonCompositions of derivatives of such polymers containing phosphorus
