Kuleon LLC

United States of America

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2025 September 2
2025 (YTD) 7
2024 6
2023 4
IPC Class
C07D 209/04 - IndolesHydrogenated indoles 6
A61K 31/33 - Heterocyclic compounds 4
A61K 31/395 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins 4
A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole 3
C07D 209/16 - Tryptamines 2
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Status
Pending 3
Registered / In Force 14
Found results for  patents

1.

SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME

      
Application Number 19170457
Status Pending
Filing Date 2025-04-04
First Publication Date 2025-09-18
Owner Kuleon LLC (USA)
Inventor
  • Forest, Jeremy
  • Gilles, David

Abstract

Serotonin receptor modulators and methods of making and using the same are disclosed herein.

IPC Classes  ?

  • C07D 471/04 - Ortho-condensed systems
  • A61K 31/343 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
  • A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
  • A61K 31/423 - Oxazoles condensed with carbocyclic rings
  • A61K 31/428 - Thiazoles condensed with carbocyclic rings
  • A61K 31/437 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
  • C07D 405/04 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
  • C07D 409/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring- member bond
  • C07D 413/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring- member bond
  • C07D 417/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings directly linked by a ring-member-to-ring- member bond
  • C07D 421/04 - Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring- member bond

2.

7-methyl indole analogs and dosage forms containing the same

      
Application Number 19215938
Grant Number 12441683
Status In Force
Filing Date 2025-05-22
First Publication Date 2025-09-11
Grant Date 2025-10-14
Owner Kuleon, LLC (USA)
Inventor Gilles, David

Abstract

Hallucinogenic and non-hallucinogenic serotonin receptor agonists are disclosed herein in addition to methods of making and using the same.

IPC Classes  ?

3.

AZEPINO ANALOGS AND METHODS OF MAKING AND USING THE SAME

      
Application Number US2024057374
Publication Number 2025/117491
Status In Force
Filing Date 2024-11-26
Publication Date 2025-06-05
Owner KULEON LLC (USA)
Inventor
  • Forest, Jeremy
  • Gilles, David

Abstract

The present application relates to azepino compounds analogs, as well as methods of using them for treating and preventing a variety of conditions.

IPC Classes  ?

  • A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
  • A61K 31/403 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
  • A61K 36/24 - Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
  • C07D 487/00 - Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups
  • A61P 25/32 - Alcohol-abuse
  • A61P 25/34 - Tobacco-abuse
  • A61P 25/36 - Opioid-abuse

4.

Serotonin Receptor Agonists and Methods of Making and Using the Same

      
Application Number 18716589
Status Pending
Filing Date 2022-12-21
First Publication Date 2025-05-08
Owner Kuleon LLC (USA)
Inventor Gilles, David

Abstract

The present application relates to serotonin receptor agonists, including azepino compounds, as well as methods of using them for treating and preventing a variety of conditions.

IPC Classes  ?

  • C07D 517/04 - Ortho-condensed systems
  • A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
  • C07D 487/04 - Ortho-condensed systems
  • C07D 495/04 - Ortho-condensed systems

5.

Mixed serotonin 5-HT2A/2C receptor agonists and methods for treating pain and depression

      
Application Number 18968441
Grant Number 12344582
Status In Force
Filing Date 2024-12-04
First Publication Date 2025-03-20
Grant Date 2025-07-01
Owner Kuleon, LLC (USA)
Inventor Gilles, David

Abstract

Hallucinogenic and non-hallucinogenic serotonin receptor agonists are disclosed herein in addition to methods of making and using the same.

IPC Classes  ?

6.

SALTS AND SOLID FORMS OF BENZOTHIOPHENE AND BENZOSELENOPHENE SEROTONIN RECEPTOR MODULATORS

      
Application Number US2024043028
Publication Number 2025/042885
Status In Force
Filing Date 2024-08-20
Publication Date 2025-02-27
Owner KULEON LLC (USA)
Inventor
  • Dickinson, Cody
  • Forest, Jeremy
  • Gilles, David

Abstract

Disclosed herein are salts and solid forms of the benzoselenophene and benzothiophene analogs described herein.

IPC Classes  ?

  • A61K 31/395 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
  • A61K 31/38 - Heterocyclic compounds having sulfur as a ring hetero atom
  • A61K 31/4743 - QuinolinesIsoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having sulfur as a ring hetero atom
  • A61K 31/33 - Heterocyclic compounds

7.

SEROTONIN RECEPTOR MODULATORS FOR THE TREATMENT OF ADDICTIONS AND OVERDOSES

      
Application Number US2024043027
Publication Number 2025/042884
Status In Force
Filing Date 2024-08-20
Publication Date 2025-02-27
Owner KULEON LLC (USA)
Inventor
  • Dickinson, Cody
  • Forest, Jeremy
  • Gilles, David

Abstract

Hallucinogenic and non-hallucinogenic serotonin receptor agonists are disclosed herein in addition to methods of using them for treating and preventing addictions and overdoses.

IPC Classes  ?

  • C07C 45/00 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atomsPreparation of chelates of such compounds
  • C10G 3/00 - Production of liquid hydrocarbon mixtures from oxygen-containing organic materials, e.g. fatty oils, fatty acids
  • A61K 31/475 - QuinolinesIsoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine

8.

Neuroplastogens and non-hallucinogenic serotonin 5-HT2A receptor modulators

      
Application Number 18741888
Grant Number 12275701
Status In Force
Filing Date 2024-06-13
First Publication Date 2024-10-17
Grant Date 2025-04-15
Owner Kuleon, LLC (USA)
Inventor Gilles, David

Abstract

Hallucinogenic and non-hallucinogenic serotonin receptor agonists are disclosed herein in addition to methods of making and using the same.

IPC Classes  ?

9.

SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME

      
Application Number US2024023960
Publication Number 2024/215824
Status In Force
Filing Date 2024-04-11
Publication Date 2024-10-17
Owner KULEON LLC (USA)
Inventor Forest, Jeremy

Abstract

The present application relates to serotonin receptor agonists, including pyridinyl compounds, as well as methods of using them for treating and preventing a variety of conditions.

IPC Classes  ?

  • A61K 31/395 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
  • A61K 31/4162 - 1,2-Diazoles condensed with heterocyclic ring systems
  • A61K 31/424 - Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
  • A61K 31/33 - Heterocyclic compounds

10.

Serotonin Receptor Agonists and Methods of Making and Using the Same

      
Application Number 18614982
Status Pending
Filing Date 2024-03-25
First Publication Date 2024-09-05
Owner Kuleon LLC (USA)
Inventor Gilles, David

Abstract

Serotonin receptor agonists, including conformationally constrained serotonin receptor agonists, and methods of making and using the same are disclosed herein.

IPC Classes  ?

  • C07D 491/052 - Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
  • C07D 209/16 - Tryptamines
  • C07D 491/048 - Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered

11.

Neuroplastogens and non-hallucinogenic serotonin 5-HT2A receptor modulators

      
Application Number 18536542
Grant Number 12012380
Status In Force
Filing Date 2023-12-12
First Publication Date 2024-06-13
Grant Date 2024-06-18
Owner Kuleon LLC (USA)
Inventor Gilles, David

Abstract

Hallucinogenic and non-hallucinogenic serotonin receptor agonists are disclosed herein in addition to methods of making and using the same.

IPC Classes  ?

12.

Methods of treating psychological disorders through the administration of serotonin 5-HT2C receptor modulators

      
Application Number 18360976
Grant Number 12187678
Status In Force
Filing Date 2023-07-28
First Publication Date 2024-04-18
Grant Date 2025-01-07
Owner Kuleon, LLC (USA)
Inventor Gilles, David

Abstract

Hallucinogenic and non-hallucinogenic serotonin receptor agonists are disclosed herein in addition to methods of making and using the same.

IPC Classes  ?

13.

SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME

      
Application Number US2023076172
Publication Number 2024/077203
Status In Force
Filing Date 2023-10-06
Publication Date 2024-04-11
Owner KULEON LLC (USA)
Inventor
  • Gilles, David
  • Forest, Jeremy

Abstract

Serotonin receptor modulators and methods of making and using the same are disclosed herein.

IPC Classes  ?

  • A61K 31/395 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
  • A61K 31/13 - Amines, e.g. amantadine
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/33 - Heterocyclic compounds

14.

TRICYCLIC AND TETRACYCLIC SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME

      
Application Number US2023022465
Publication Number 2023/225043
Status In Force
Filing Date 2023-05-17
Publication Date 2023-11-23
Owner KULEON LLC (USA)
Inventor Gilles, David

Abstract

Tricyclic and tetracyclic compounds, analogs, and methods of making and using the same.

IPC Classes  ?

  • A61K 31/395 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
  • A61K 31/404 - Indoles, e.g. pindolol
  • A61K 31/095 - Sulfur, selenium or tellurium compounds, e.g. thiols
  • A61K 31/10 - SulfidesSulfoxidesSulfones
  • A61K 31/33 - Heterocyclic compounds

15.

Benzoselenophene, benzothiophene, and benzofuran analogs and methods of modulating the serotonin 5-HT2C receptor

      
Application Number 18306652
Grant Number 11780807
Status In Force
Filing Date 2023-04-25
First Publication Date 2023-08-17
Grant Date 2023-10-10
Owner Kuleon, LLC (USA)
Inventor Gilles, David

Abstract

Hallucinogenic and non-hallucinogenic serotonin receptor agonists are disclosed herein in addition to methods of making and using the same.

IPC Classes  ?

16.

SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME

      
Application Number US2022053583
Publication Number 2023/122135
Status In Force
Filing Date 2022-12-21
Publication Date 2023-06-29
Owner KULEON LLC (USA)
Inventor Gilles, David

Abstract

The present application relates to serotonin receptor agonists, including azepino compounds, as well as methods of using them for treating and preventing a variety of conditions.

IPC Classes  ?

  • C07D 517/14 - Ortho-condensed systems
  • A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

17.

POLYPODAL SEROTONERGIC COMPOUNDS AND PRODRUGS OF SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS

      
Application Number US2022053910
Publication Number 2023/122320
Status In Force
Filing Date 2022-12-23
Publication Date 2023-06-29
Owner KULEON LLC (USA)
Inventor Gilles, David

Abstract

Monopodal and polypodal serotonergic drugs, including prodrugs of serotonin receptor agonists and antagonists.

IPC Classes  ?

  • C07D 209/16 - Tryptamines
  • C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
  • C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
  • C07D 413/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
  • C07D 403/06 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
  • A61K 31/4045 - Indole-alkylaminesAmides thereof, e.g. serotonin, melatonin
  • A61P 25/22 - Anxiolytics