Provided is an antiperspirant composition from which an even coating can be formed on the skin. This antiperspirant composition comprises ammonium glycyrrhizinate (component A), chlorohydroxyaluminum (component B), ethanol (component C), and water (component D), wherein the content of the component A is 0.05-1.0 mass%, the content of the component B is 3.0-30.0 mass%, the mass ratio of the content of the component C to the content of the component A is 20.0 or greater, the mass ratio of the content of the component D to the content of the component A is 10.0 or greater, and the mass ratio of the content of the component D to the content of the component B is 0.8 or greater.
Provided is a hair cleansing agent composition capable of improving foaming properties and foam elasticity and suppressing the squeakiness of hair during washing with water. A hair cleansing agent composition according to the present invention contains an N-acylamino acid-based surfactant (component A), an alkyl glycol carboxylic acid-based surfactant (component B), a cationized polymer (component C), and water (component D).
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
The present invention provides a composition excellent in antiseptic property and safety. This preservative composition contains the following ingredients A and B. Ingredient A: 1,2-decanediol Ingredient B: at least one selected from the group consisting of 7-9 C 1,2-alkanediol, sodium polyphosphate, and ethylhexylglycerol
Provided is a water-in-oil emulsion cosmetic composition that, compared to oil-based cosmetic compositions having the same properties, can realize better spread. The water-in-oil emulsion cosmetic composition according to the present invention comprises: an oily component selected from the group consisting of animal/vegetable oils and hydrocarbon oils, having a melting point of 65-100°C, and being solid at 25°C (component A); an oily component selected from the group consisting of vegetable oils and fatty acid triglycerides, and being liquid at 25°C (component B); a non-ionic surfactant having a linear saturated alkyl chain with at least 13 carbons and having an HLB value of 2.8-8.0 (component C); and water (component D), where the content of component D is 15.0-50.0 mass%.
Provided is an emulsified hair cosmetic composition that exhibits an excellent finger combability upon application and after heat treatment, and that exhibits an excellent post-heat-treatment hair manageability and an excellent persistence thereof. The emulsified hair cosmetic composition according to the present invention contains levulinic acid (component A), a cationic surfactant (component B), a C8-24 aliphatic alcohol (component C), a silicone compound (component D), and water (component E).
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
Provided is a haircare emulsion composition which satisfactorily spreads and is capable of heightening hair-raising power. This haircare emulsion composition comprises: component A, which is either component A1 or component A2, the component A1 being a vegetable oil having a melting point of 30-50°C and/or an ester oil having a melting point of 30-50°C and the component A2 being the component A1 and vaseline; a wax (component B) having a melting point exceeding 50°C; a specific thickening polymer (component C); and water (component D). The content of the component A1 is 50.0 mass% or higher with respect to the component A which is taken as 100 mass%, the total content of the component A and the component B is 10.0-40.0 mass%, the content of the component A is 10.0-50.0 mass% with respect to the total content of the component A and the component B, which is taken as 100 mass%, and the content of the component C is 0.1-1.0 mass%.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
A61K 8/92 - Oils, fats or waxesDerivatives thereof, e.g. hydrogenation products
A61Q 5/06 - Preparations for styling the hair, e.g. by temporary shaping or colouring
7.
REGULATOR FOR PRIMARY CILIA OF IMMUNE-RELATED CELLS AND USE THEREOF
The present invention addresses the problem of providing a regulator for primary cilia of immune-related cells and a technique for the use thereof. Use is made of a regulator for primary cilia of immune-related cells that contains at least one selected from the group consisting of silymarin, silybin, dehydrosilybin, annonacin and quercetin.
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/357 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY (Japan)
Inventor
Toriyama, Manami
Fujita, Fumitaka
Okada, Fumihiro
Morita, Akimichi
Nakamura, Motoki
Abstract
The present invention provides a novel method for detecting an indicator of T cell lymphoma. The method for detecting an indicator of T cell lymphoma includes the step of detecting acetylated tubulin in a T cell that has been collected from a subject.
The purpose of the present invention is to provide an aerosol spray hair cosmetic whereby a matte texture having considerably reduced gloss can be imparted to hair, and the occurrence of a precipitate in the aerosol spray hair cosmetic immediately after manufacture thereof can be suppressed. This aerosol spray hair cosmetic comprises an aerosol spray container, a hair cosmetic composition, and a propellant, the hair cosmetic composition including an anionic film-forming polymer and/or an amphoteric film-forming polymer (component A), a silicone-modified acrylic resin (component B), and ethanol (component C), the total content of component A and component B in 100 mass% of the hair cosmetic composition being 1.5-12.0 mass%, and the mass ratio (content of component B/content of component A) thereof being 0.3-6.50, and the propellant including dimethyl ether (component X).
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
A61K 8/891 - Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
A61Q 5/06 - Preparations for styling the hair, e.g. by temporary shaping or colouring
Provided is a cosmetic composition which can be improved in the feeling of adhesion and applicability to a subject while also improving the richness thereof. The cosmetic composition according to the present invention comprises a compound represented by formula (1) (a component A), a compound represented by formula (2) (a component B), a polyglycerin fatty acid ester in which 2 to 6 fatty acids are bonded via ester bonds to polyglycerin and the average number of moles of glycerin added is 4 to 12 (a component C), an aliphatic alcohol having 12 to 24 carbon atoms (a component D) and water (a component E). R1-N+333X-(1) (In formula (1), R1represents a linear or branched aliphatic hydrocarbon group having 12 to 22 carbon atoms, and X-represents Cl-or Br-). R2366-N+333Z-(2) (In formula (2), R2represents a linear or branched aliphatic hydrocarbon group having 11 to 21 carbon atoms, and Z-represents Cl-or Br-.)
A61K 8/891 - Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
A61K 8/898 - Polysiloxanes containing atoms other than silicon, carbon, oxygen and hydrogen, e.g. dimethicone copolyol phosphate containing nitrogen, e.g. amodimethicone, trimethyl silyl amodimethicone or dimethicone propyl PG-betaine
A61K 8/92 - Oils, fats or waxesDerivatives thereof, e.g. hydrogenation products
PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY (Japan)
Inventor
Toriyama, Manami
Fujita, Fumitaka
Okada, Fumihiro
Morita, Akimichi
Nakamura, Motoki
Abstract
Provided is a novel method for detecting an indicator of T-cell lymphoma. This method for detecting an indicator of T-cell lymphoma comprises a step for detecting acetylated tubulin in T cells collected from a subject.
C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
A61K 31/136 - Amines, e.g. amantadine having aromatic rings, e.g. methadone having the amino group directly attached to the aromatic ring, e.g. benzeneamine
A61K 31/537 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosolsInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
Provided is a hairstyling agent composition with which a matte effect can be provided even when in the form of a water-based hairstyling agent. The hairstyling agent composition according to one embodiment of the present invention comprises ingredient A, which is an emulsion of a polymer having a mean particle size of 30 nm or larger, ingredient B, which is a water-soluble thickener, and ingredient C, which is water, wherein the ingredient A content is 0.1 to 20.0% by mass.
Provided is a cosmetic composition in which caking is suppressed while the cosmetic composition contains a powder. A cosmetic composition containing: component (A), which is a powder that is an octenyl succinic acid starch ester metal salt and/or talc; component (B), which is an oily component having an IOB value of 0-0.45; component (C), which is ethanol; and component (D), which is water, the component (A) content proportion being 0.01-15.0 mass%, the component (C) content proportion being 25.0-80.0 mass%, and the mass ratio [component (B)/component (A)] of component (B) and component (A) being 0.003-3.0.
B01J 13/00 - Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided forMaking microcapsules or microballoons
Provided is an aerosol spray hairstyling product that can easily be styled, has superior styling power to shape the hair and superior restylability, and has superior spray stability. The aerosol spray hairstyling product according to the present invention comprises an aerosol spray container, a hairstyling product composition, and a propellant including liquefied petroleum gas. The hairstyling product composition can be sprayed in mist form. The hairstyling product composition: contains a component A including at least one component A1 from among polyoxyethylene-hardened castor oil (component A1) and a polyoxyethylene alkyl ether (component A2), ethanol (component B), and water (component C); does not contain or contains no more than 0.1% by mass of a coating-forming polymer; and does not contain or contains no more than 0.1% by mass of a thickener. The included amount of component A1 is 50.0% by mass or more out of 100% by mass of component A. The included amounts of components A, B, and C are 10.0–48.0% by mass, 30.0–85.0% by mass, and 5.0–25.0% by mass out of 100% by mass of the hairstyling product composition.
NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION, HEALTH AND NUTRITION (Japan)
Inventor
Toriyama, Manami
Fujita, Fumitaka
Okada, Fumihiro
Ishii, Ken
Abstract
Provided is a method whereby an objective indicator of an immune-related disease can be rapidly and easily detected, the method comprising detecting, as an indicator of an immune-related disease, a difference in the result of observing a primary cilium of an immune-related cell between a subject specimen and a normal specimen.
An immortalized sweat gland myoepithelial cell which expresses α-SMA and pan-cytokeratin and has a sphere forming ability after subculture at least 5 times. A method for producing immortalized sweat gland myoepithelial said method comprising: while culturing a cell structure, wherein sweat gland myoepithelial cells are exposed on a surface, in a state of being suspended in a medium, transferring an immortalizing gene into the cells; and then culturing the transgenic structure thus obtained in a state of being suspended in the medium to thereby obtain immortalized sweat gland myoepithelial cells.
Provided is a hairstyling agent composition in which the viscosity increase caused by the incorporation of a clay mineral is suppressed. The hairstyling agent composition according to one aspect of the present invention comprises a component A: a clay mineral, component B: polyphosphoric acid or a salt thereof, and component C: water.
Provided is an emulsified hair-dressing composition containing diatomite, and methylpolysiloxane which has a dynamic viscosity of 3-400 cSt at 25°C, wherein a mass ratio of the content of the diatomite to the content of the methylpolysiloxane which has a dynamic viscosity of 3-400 cSt at 25°C is 0.12-3.0.
Provided is a method for observing a sebaceous gland, the method making it possible to observe dynamics of a sebaceous gland which dynamics are close to dynamics of a sebaceous gland in a living body. The method includes: an anchoring step of anchoring a sebaceous gland structure to a support so that a sebaceous gland that is included in the sebaceous gland structure and is to be observed and the support are not in biological contact with each other, the sebaceous gland structure being obtained by removing all or part of each of dermis and hypodermis from a skin tissue; and an observation step of observing the sebaceous gland structure obtained in the anchoring step.
Provided is a hairstyling agent composition in which α-ketoglutaric acid is used as a hairstyling component. Also provided is a hairstyling agent composition having excellent moisture resistance for styled hair. This hairstyling agent composition contains component (A), α-ketoglutaric acid, and component (B), water and/or ethanol. With regard to the hairstyling agent composition, the content ratio of component (A) is 0.01 to 0.8 mass% and the pH is 6.8 or less.
A hair styling composition containing: component (A): one or more compounds selected from the group consisting of polyoxyalkylene alkyl ether phosphoric acids and salts thereof, and polyoxyalkylene alkenyl ether phosphoric acids and salts thereof; component (B): a non-ionic surfactant; component (C): a wax having a melting point of 25°C or higher and/or a hydrocarbon oil having a melting point of 25°C or higher; and component (D): a silicone oil having a kinematic viscosity at 25°C of 60 cSt or lower, the hair styling composition being such that the component (C) content is 6.0-28.0 mass% and the component (D) content is 1.0-15.0 mass%.
A skin cleanser composition which contains a scrubbing agent, and which is configured such that: the scrubbing agent contains at least one fatty acid ester that is selected from the group consisting of tri-fatty acid (C14-26) glyceryl esters, fatty acid (C14-26) polyglyceryl esters and tetra-fatty acid (C14-26) pentaerythtyl esters; and the average particle diameter of the scrubbing agent is 100-1,700 μm.
Provided is a skin cleanser composition that is gentle on the skin yet has cleansing power comparable to conventional scrubbing-agent-containing cleansers and peeling cleansers. A skin cleanser composition according to the present invention contains: a higher fatty acid and/or a salt thereof (component (A)); fibrous cellulose (component (B1)) and/or defatted rice bran (component (B2)); a cationic polymer (component (C)); and water (component (D)). The component (A) content rate is 5.0–50.0 mass%, the component (B1) and/or component (B2) content rate is 0.1–10.0 mass%, and the component (C) content rate is 0.05–2.0 mass%.
Provided is a method for observing a sebaceous gland whereby the dynamics of the sebaceous gland can be observed under close to in vivo conditions. The method for observing a sebaceous gland comprises: a fixation step for fixing a sebaceous gland structure, which is prepared by removing the dermis and the subcutaneous tissue, each partly or completely, from a skin tissue, to a support in such a manner that the sebaceous gland to be observed in the sebaceous gland structure is not brought into biological contact with the support; and an observation step for observing the sebaceous gland structure obtained in the fixation step.
Provided is a cosmetic that: has two aqueous layers and an oil layer that are stable; and has excellent aesthetics. The cosmetic contains: a dextrin (component A) having a weight-average molecular weight of 50,000–300,000; a polyethylene glycol (component B) having a weight-average molecular weight of 4,000–30,000; an electrolyte (component C); an ionic surfactant (component D); water (component E), and an oily component (component F). Relative to the total volume of the cosmetic excluding component F, the content ratio of component A is 2.0%–10.0% by mass, the content ratio of component B is 2.0%–10.0% by mass, and the content ratio of component C is 0.05%–1.4% by mass.
Provided is a skin cosmetic composition capable of including a comparatively large amount of oil and having excellent transparency and storage stability. The skin cosmetic composition contains a component A, a component B, a component C, a component D, a component E, a component F, a component G, and a component H. The mass ratio (B/A) of component B to component A is 5.5–18.0. Component A is a phospholipid; component B is a polyoxyethylene sterol ether having an average of 15–50 oxyethylene moles added thereto and/or a polyoxyethylene stanol ether having an average of 15–50 oxyethylene moles added thereto; component C is a C12–24 monovalent aliphatic alcohol having a branched chain; component D is at least one type of polyvalent alcohol selected from the group consisting of propylene glycol, dipropylene glycol, and 1, 3–butylene glycol; component E is water; component F is a sterol; component G is an oil; and component H is a polyoxyethylene hydrogenated castor oil having an average of 5–30 oxyethylene moles added thereto.
Provided is a composition for skin cosmetics capable of giving a smooth feeling while suppressing a dry skin feeling after use. This composition for skin cosmetics contains component (A): talc and/or silica, component (B): starch aluminum octenylsuccinate, component (C): ethanol, and component (D): water, wherein the content of the component (A) is 0.5-15.0 mass%, the content of the component (B) is 0.5-15 mass%, the content of the component (C) is 20.0-70.0 mass%, and the content of the component (D) is 10.0-75.0 mass%.
Provided is a hair styling agent composition that has excellent coatability and hair-style hold as well as excellent hair-style retention for fine hair. This hair-styling agent composition comprises: (component A) a hydrocarbon selected from the group consisting of microcrystalline waxes and polyethylene waxes; (component B) a hydrocarbon selected from the group consisting of paraffin waxes, Fischer-Tropsch waxes, and ceresin; and (component C) dimethylpolysiloxane having a kinetic viscosity of 0.5-2.5 mm2/s. The content of component A is 0.5-20.0% by mass, and the content of component B is 0.5-20.0% by mass. The mass ratio of the content of component A to component B is 0.20-10.0.
Provided is a hair cosmetic composition that enables better conditioning properties and higher hair dyeing strength. This hair cosmetic composition contains a basic dye (component A) and polyoctanium-67 (component B), and contains no anionic surfactant or contains no more than 0.1 mass% anionic surfactant, contains no cationic surfactant or contains no more than 0.5 mass% cationic surfactant, and contains no amphoteric surfactant or contains no more than 0.5 mass% amphoteric surfactant.
This skin cleanser composition contains: 5.0-50 mass% of a higher fatty acid and/or a salt thereof; 1.0-10 mass% of silica; 0.1-4.0 mass% of a cationic polymer; and 0.5-10 mass% of a sugar alcohol.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
A61K 8/19 - Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
Provided is an aerosol foam hairstyling agent composition which exhibits an excellent styling ability for standing hair upright, styling ability for firmly consolidating hair into bundles, application properties, and usability. This aerosol foam hairstyling agent composition contains: 10.0-50.0 mass% of a compound (component A) selected from the group consisting of polyoxyethylene hydrogenated castor oil (60E.O.-120E.O.), polyoxyethylene cetyl ether (2E.O.-60E.O.), and polyoxyethylene stearyl ether (2E.O.-60E.O.); polyoxyethylene hydrogenated castor oil (component B) having a polyoxyethylene group exhibiting an average added molar number of 30-50; ethanol (component C); and 10.0-86.0 mass% of water (component D). Therein, the mass ratio of component B/component A is 0.10-1.00, and the mass ratio of component C/component A is 0.30-1.80.
Provided is a hair cosmetic that is an oil gel containing water and polyhydric alcohol, the hair cosmetic imparting softness to hair, providing exceptional styling ability, and being capable of suppressing stickiness. A hair cosmetic that contains the following component (A), the following component (B), the following component (C), the following component (D), the following component (E), and the following component (F), the component (A) content being 0.1-5.0% by mass, the component (B) content being 3.0-50.0% by mass, the component (C) content being 0.5-20.0% by mass, the component (D) content being 0.3-20.0% by mass, the component (E) content being 10.0-95.0% by mass, and the component (F) content being 0.3-50.0% by mass. Component (A): one or more compounds selected from the group consisting of polyoxyalkylene alkyl ether phosphoric acid, salts thereof, polyoxyalkylene alkenyl ether phosphoric acid, and salts thereof. Component (B): one or more polyhydric alcohols selected from the group consisting of glycerin, diglycerin, polyethylene glycol, and sugar alcohols. Component (C): water. Component (D): a silicone compound having a viscosity at 25°C of 10,000,000-30,000,000 mPa∙s. Component (E): a volatile oil. Component (F): an ester oil and/or a vegetable oil.
A61K 8/891 - Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
A61K 8/892 - Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a hydroxy group, e.g. dimethiconol
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
Provided is an emulsified hairdressing composition which shows a good hair raising ability (lift-up ability), allows to easily form a hair tress and is smoothly spreadable on the hair. The emulsified hairdressing composition comprises: component (A) carnauba wax; component (B) castor oil; and component (C) one or more oily agents selected from the group consisting of a cyclic silicone, methyl trimethicone, ethyl trisiloxane, trisiloxane, caprylyl methicone and dimethyl polysiloxane having a viscosity at 25°C of 0.1-2.0 mPa.s.
Provided is a gel cosmetic that imparts a moist and fresh feeling at application, shows an elastic texture at application and exerts a long-lasting coverage effect. An oil-in-water type gel cosmetic which comprises components (A) to (E) as specified below, wherein: the content of component (D) is 0.1-1.0 mass%; the content of component (B) is 0.2-1.2 mass%; and the ratio by mass of the content of component (B) to the content of component (A) [component (B)/component (A)] is 1.0-15.0. Component (A): a polymer comprising at least a structural unit derived from (meth)acrylic acid and/or an alkyl (meth)acrylate and a structural unit derived from a (meth)acrylic acid polyoxyethylene alkyl ether. Component (B): a polymer comprising a structural unit derived from acryloyldimethyl taurate. Component (C): a specific monoglycerol fatty acid ester. Component (D): an aliphatic alcohol having 12-24 carbon atoms. Component (E): water.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
A61K 8/891 - Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION, HEALTH AND NUTRITION (Japan)
Inventor
Fujita Fumitaka
Saito Kaori
Okada Fumihiro
Ishii Ken
Abstract
Provided is a TRP channel activity inhibitor capable of effectively inhibiting the activity of TRP channels, wherein the TRP channel activity inhibitor is characterized by containing aluminum ions as an active ingredient for inhibiting the activity of TRP channels.
Provided is an oil-based cosmetic that imparts a feeling of thickness when applied and exhibits excellent massaging properties. This oil-based cosmetic contains a component (A) and has a flash point of 190-215°C. Component (A): a polyglycerol fatty acid ester, which is an ester between a polyglycerol and an unsaturated fatty acid and/or branched-chain fatty acid, and which has an HLB value of 8.0-14.0.
An external preparation for skin, characterized by comprising ethanol, a powder, a cationic polymer and water, wherein the ethanol content is 50.0 to 80.0% by mass.
A61K 8/84 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions other than those involving only carbon-to-carbon unsaturated bonds
Provided is an antiperspirant which serves to control secretion of sweat from sweat glands and is capable of doing so by acting on sweat glands without closing sweat pores, the antiperspirant containing, as an active ingredient to control secretion of sweat from sweat glands, at least one type of pentacyclic compound selected from the group consisting of compounds represented by formula (I) and derivatives thereof, and compounds represented by formula (VII) and derivatives thereof.
A61K 31/56 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids
A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
The present invention pertains to an aerosol product having a liquid concentrate and a propellant filled in a container body, wherein the liquid concentrate contains components A, B, and C indicated below, and the propellant contains a liquefied petroleum gas. Such an aerosol product exhibits high stability of lysozyme chloride, and thus is preferably applicable for use in deodorant agents. Component A: lysozyme chloride. Component B: non-ionic surfactant. Component C: water.
Provided is an antiperspirant composition having an excellent antiperspiration effect, and an excellent prolonged body-odor prevention effect. An antiperspirant composition according to the present invention contains: an ethanol (component A); an antiperspirant component (component B); a hydrophobized hydroxyalkyl cellulose (component C); a film-forming polymer (component D) selected from the group consisting of an acrylic acid type film-forming polymer (component D1) and a nonionic film-forming polymer (component D2); and water (component E).
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION, HEALTH AND NUTRITION (Japan)
Inventor
Saito Kaori
Fujita Fumitaka
Okada Fumihiro
Ishii Ken
Abstract
Provided is a method for evaluating a test sample, said method making it easy to evaluate whether a test sample has the effect of suppressing cytokine production in skin cells, wherein the cytokine production suppressing effect of the test sample is evaluated on the basis of a physiological event triggered by the test sample through TRPM4 in TRPM4-expressing cells.
C07D 417/10 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing aromatic rings
C07J 43/00 - Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta[a]hydrophenanthrene skeleton
NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION, HEALTH AND NUTRITION (Japan)
Inventor
Toriyama Manami
Fujita Fumitaka
Okada Fumihiro
Ishii Ken
Abstract
Provided is a method whereby an objective indicator of an immune-related disease can be rapidly and easily detected, the method comprising detecting, as an indicator of an immune-related disease, a difference in the result of observing a primary cilium of an immune-related cell between a subject specimen and a normal specimen.
A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
A61P 37/06 - Immunosuppressants, e.g. drugs for graft rejection
A61P 43/00 - Drugs for specific purposes, not provided for in groups
This actuator (1) for an aerosol container is provided with: a spherical rolling body 3; and a holder 4 having a recessed section 41 that rollably holds the rolling body. The bottom section of the holder 4 is provided with a stem connection part 42 that has a discharge passage 7 of the content of the aerosol container 2 and that is fitted to a stem 23, the discharge passage 7 communicating with an injection hole 77 formed inside the recessed section 41. In the recessed section 41, a plurality of spherical protrusions 81, 82 are provided protruding to the same height and spaced apart from each other on each of the internal surface near the bottom section and the internal surface along an opening edge. The discharge passage 7 is provided with a middle orifice that reduces the injection pressure of the content. Thus, the rolling body 3 rolls smoothly at all times, a certain amount of the content may be stably supplied, and the rolling body 3 is prevented from popping out.
Provided is a second preparation for such a hair treatment agent that a first preparation and a second preparation can be mixed together satisfactorily and the attachability of the resulting mixture onto hair can be improved. A second preparation for a hair treatment agent according to the present invention is a second preparation to be used in a multi-pack hair treatment agent provided with at least a first preparation containing no oxidation dye or containing an oxidation dye and also containing an alkali agent and a second preparation containing an oxidizing agent. The second preparation contains a tertiary amine-type cationic surfactant.
Provided is a hairdressing agent composition that exhibits an excellent spreadability during application, an excellent curl reproducibility, and an excellent curl retention. The hairdressing agent composition comprises: a component (A): an oil that is in a liquid form at 25°C; a component (B): xanthan gum; a component (C): an acrylic acid-based thickener; and a component (D): a cationic film-forming polymer. The component (D) is preferably Polyquaternium-11. This hairdressing agent composition preferably comprises a component (E): a polyoxypropylene sorbitol. The component (C) is preferably a carboxy vinyl polymer and/or an alkyl-modified carboxy vinyl polymer.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
A61K 8/891 - Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
A61Q 5/06 - Preparations for styling the hair, e.g. by temporary shaping or colouring
50.
COMPOSITION FOR HAIR TREATMENT AND MIST COSMETIC FOR HAIR TREATMENT
Provided is a composition for hair treatment, the composition being filled into a container and being capable of sustaining dressed hairstyle for a long time without collapse of the dressed hairstyle even if an external impact is exerted on hair, when the composition is discharged in a mist form through a pump-type dispenser or a trigger-type dispenser. This composition for hair treatment, which is filled into a container and is discharged in a mist form through a pump-type dispenser or a trigger-type dispenser, contains: a film-forming polymer (component A); an oxidation alkylene addition polymer of sugar alcohol (component B); and an ethanol (component C).
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
Provided is a hairstyling composition which is in a highly stable state and can give styled hair having heightened moisture resistance. The hairstyling composition of the present invention comprises a polyoxyethylene alkyl ether (component A) in which the average number of moles of the added oxyethylene groups is 20-50 and the alkyl has 16-22 carbon atoms, a film-forming polymer (component B) having a weight-average molecular weight of 30,000-150,000 and obtained using an alkyl (meth)acrylate as an essential monomer ingredient, polyoxyethylene hydrogenated castor oil (component C), and water (component D), wherein the content of the component A is 30.0-45.0 mass%, the content of the component B is 0.1 mass% or greater, and the content of the component C is 0.1-5.0 mass%, the mass ratio of the content of the component A to the content of the component B being 5.0 or greater.
A61K 8/39 - Derivatives containing from 2 to 10 oxyalkylene groups
A61K 8/02 - Cosmetics or similar toiletry preparations characterised by special physical form
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
The present invention relates to an oil-in-water-type skin cosmetic containing: an oil selected from the group consisting of cholesterol fatty acid esters, cholestanol fatty acid esters, phytosterol fatty acid esters, and phytostanol fatty acid esters and a component selected from the group consisting of ultraviolet absorbers; a nonionic surfactant having a polyoxyethylene chain the HLB of which is 14.5-20.0; a polymer or the like containing a structural unit derived from acryoyldimethyltaurate; and water. The present invention provides an oil-in-water-type skin cosmetic having excellent stability as well as excellent water resistance and feel on use.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
Provided is a semi-solid cleaning agent having superior storage stability although the amount of a higher fatty acid and a salt thereof blended into the semi-solid cleaning agent is small. This semi-solid cleaning agent contains a component (A) that is a higher fatty acid and/or a salt thereof, a component (B) that is a higher alcohol which is solid at 20ºC and has 16-20 carbon atoms, and a component (C) that is a carboxyvinyl polymer, wherein the content ratio of the component (A) is 5.0-25.0 mass%. The component (C) is preferably an alkyl-modified carboxyvinyl polymer.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
Provided is a foamy skin cleanser in which a stock solution and a propellant are filled in an aerosol container, wherein the stock solution is characterized by containing components A, B, C and D below, Component A: a higher fatty acid and/or a salt thereof Component B: a fatty acid ester oil which is liquid at room temperature Component C: water Component D: a polyethylene glycol fatty acid ester-type nonionic surfactant. The foamy skin cleanser according to the present invention may be used for the face, hands, body, scalp or hair, etc.
[Problem] To allow the manufacturing costs of a nozzle unit (3) for simultaneously discharging two kinds of contents from a first stem (42) and a second stem (43) which are provided adjacent to each other in the radial direction on one end side of a cylindrical aerosol can (2) to be reduced compared to the discharge tools of patent documents 1 and 2; and allow a component detachment operation accompanying a passage cleaning process for discharging contents to be simply performed for the nozzle unit (3). [Solution] This nozzle unit (3) is composed of the two components of a base (5) and a discharge head (6). The discharge head (6) has a nozzle (61) and a frame part (62). The nozzle (61) is connected to each of the first stem (42) and the second stem (43), and merges the contents, respectively discharged from the first stem (42) and the second stem (43), to thereby discharge the contents to the outside. The frame part (62) has a lock section (62e) detachably locked to the base (5), responds to a pressing operation of the nozzle (61), and supports the nozzle (61) so that the nozzle can be tilted. The base (5) has an locked part (52a) to which the lock section (62e) of the discharge head (6) is locked.
B05B 9/04 - Spraying apparatus for discharge of liquid or other fluent material without essentially mixing with gas or vapour characterised by means for supplying liquid or other fluent material with pressurised or compressible containerSpraying apparatus for discharge of liquid or other fluent material without essentially mixing with gas or vapour characterised by means for supplying liquid or other fluent material with pump
B65D 81/32 - Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
Provided is an aerosol spray hairdressing agent composition that is capable of 1) improving hair styling performance during hairdressing, 2) enhancing the retention of hair styling performance, 3) enhancing the performance of re-styling of hair, and 4) providing a matte and natural finish for the hair. The aerosol spray hairdressing agent composition according to the present invention comprises an anionic film-forming polymer (component A), silica (component B), and polyoxyethylene hydrogenated castor oil (component C) containing a polyoxyethylene group having an average addition molar number of 50-100, wherein the contained amount of component A is 0.4-3.5 mass%, and the contained amount of component B is 1.0-10.0 mass%, and the contained amount of component C is 0.8-5.5 mass%.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
A method for observing the dynamics of sweat glands and a method for evaluating a substance of interest, which are useful for development of a preparation for external application, such as a cosmetic. In each of the methods, an observation sample is used, which is prepared by staining all sweat glands, which are isolated alive, with a staining reagent, and then holding the all sweat glands on a support using at least one material selected from the group consisting of collagen, agarose, basement membrane matrix, poly-D-lysine and a membrane.
An immortalized sweat gland myoepithelial cell which expresses α-SMA and pan-cytokeratin and has a sphere forming ability after subculture at least 5 times. A method for producing immortalized sweat gland myoepithelial cells, said method comprising: while culturing a cell structure, wherein sweat gland myoepithelial cells are exposed on the surface, in a state of being suspended in a medium, transferring an immortalizing gene into the cells; and then culturing the transgenic structure thus obtained in a state of being suspended in the medium to thereby obtain immortalized sweat gland myoepithelial cells.
Provided is a foamed skin cleanser used in aerosol-type foamer containers, wherein the foamed skin cleanser has excellent foaming power, can form a dense and creamy foam, and also has excellent foaming sustainability (foaming persistence). This foamed skin cleanser contains a stock solution and a propellant which are filled in an aerosol container, the stock solution containing component A: N-acylamino acid salt, component B: polyglycerin fatty acid ester, component C: monoglycerin fatty acid ester, component D: xanthan gum and/or cellulosic thickener, component E: polyhydric alcohol, and component F: water.
Provided is a hairdressing agent composition in which a reduction in viscosity over time is suppressed while containing an acrylic film-forming polymer and a thickening agent. This hair dressing agent composition contains the following components A, B, C, and D: component A, phytic acid; component B, an acrylic polymer obtained using monomer components B1 and B2 as monomer components (monomer component B1, an alkyl (meth)acrylate ester, and monomer component B2, an alkylacrylamide and/or diacetone acrylamide); component C, a thickening agent; and component D, water.
A61K 8/55 - Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing phosphorus
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
A61Q 5/06 - Preparations for styling the hair, e.g. by temporary shaping or colouring
Provided is a hairdressing agent composition which exhibits excellent operability when hairdressing, can form fine hair bundles, which is excellent in terms of hair bundle smoothing characteristics (arranging ability), causing hair bundles to stand up from the roots and maintaining a hairstyle for a long period of time, and suppresses glossiness following hairdressing. The hairdressing agent composition contains: A, one or more powders selected from the group consisting of silica, talc, titanium oxide and mica; B, polyoxyethylene hardened castor oil including B1 (polyoxyethylene hardened castor oil having an average of 45-65 added moles of EO) and B2 (polyoxyethylene hardened castor oil having an average of 75-125 added moles of EO); C, a polymer obtained using (meth)acrylic acid and/or an alkyl ester of (meth)acrylic acid and a (meth)acrylic acid polyoxyethylene alkyl ether; D, a carboxyvinyl polymer and/or an alkyl-modified carboxyvinyl polymer; and E, water. The content of component A is 0.5-5.0 mass%, the total content of components B1 and B2 is 3.0-25.0 mass%, the content of component C is 0.1-1.5 mass%, the content of component D is 0.05-1.5 mass%, and the [B1/(B1+B2)] mass ratio is 0.1-0.9.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
A61K 8/92 - Oils, fats or waxesDerivatives thereof, e.g. hydrogenation products
A61Q 5/06 - Preparations for styling the hair, e.g. by temporary shaping or colouring
A method for observing a sebaceous gland, the method being useful for such applications as developing a cosmetic material or other external preparation, and including (I) a step for culturing, in a floating state in a medium, a sebaceous gland structure in which the dermis and all or a portion of the subcutaneous tissue is removed from a skin tissue, and (II) a step for observing the cultured sebaceous gland structure obtained in step (I).
The present invention provides a hair dressing composition that is capable of 1) increasing the volume of hair, 2) forming numerous fine hair bundles, 3) bringing together the tips of fine hair bundles, and 4) providing curly shapes to the fine hair bundles. The hair dressing composition according to the present invention comprises: silica (component A); a compound (component B) selected from the group consisting of polyoxyethylene-polyoxypropylene random copolymers having a number average molecular weight of 10,000-20,000 and a polyoxypropylene sorbitol having a number average molecular weight of 300-1,000; polyoxyethylene hydrogenated castor oil (component C); and polyglyceryl eicosanedioic acid/tetradecanedioic acid (component D), wherein the respective contained amounts of component A, component B, component C, and component D fall within specific ranges, and the mass ratio of the contained amount of component D to the contained amount of component A falls within a specific range.
This TRPA1 activity inhibitor contains a compound represented by formula (I) wherein R1, R2, R3 and R4 each independently represent a hydrogen atom or a methyl group, and R5, R6, R7 and R8 each independently represent a hydrogen atom, a methyl group or -O-R9-OH (in the formula, R9 represents an alkylene group optionally having a substituent group), provided that at least one group of R5, R6, R7 and R8 is -O-R9-OH.
Provided is a hair dye composition having an exceptional hyperchromic effect for nonionic blue dyes. A hair dye composition containing a component A: HC blue 2 and a component B: glyceryl caprate. The mass ratio [component B/component A] of the component B content with respect to the component A content is preferably 0.1 or higher. The component A content in the hair dye composition is preferably 0.1-3.0% by mass, and the component B content is preferably 0.01-3.0% by mass.
Provided is a hair dye composition which suppresses dyeing affinity with skin, despite having sufficient dyeing affinity with hair. This hair dye composition includes: component A, namely HC blue 16; component B, namely at least one dye selected from the group consisting of basic orange 31, basic red 51, basic red 76, basic yellow 87, and basic yellow 57; component C, namely HC blue 2; and component D, namely at least one dye selected from the group consisting of HC yellow 4 and HC yellow 2. It is preferable that the content of component A be 0.05-3.0 mass%, the content of component B be 0.005-1.5 mass%, the content of component C be 0.1-1.5 mass%, and the content of component D be 0.01-0.5 mass%.
The present invention pertains to a skin cosmetic which contains: a nonionic surfactant (component A); one or more types of compounds (component B) selected from a group consisting of C5-10 1,2-alkanediol and phenoxyethanol; dipropylene glycol (component C); myristoyl glutamate (component D); and water (component E).
An emulsified cosmetic containing components A-E, wherein the content of component A is 0.1-1.0 mass%, the content of component B is 0.4 mass% or less, the content of component C is 0.3 mass% or less, the content of component D is 4.0 mass% or less, the mass ratio (component B/component A) of component B to component A is 0.10 or higher, the mass ratio (component C/component A) of component C to component A is 0.02 or higher, and the mass ratio (component D/component A) of component D to component A is 0.4-7.0, inclusive. Component A: (acrylate/beheneth-25 methacrylate) copolymer. Component B: carboxyvinyl polymer and/or alkyl-modified carboxyvinyl polymer. Component C: xanthan gum. Component D: phospholipid. Component E: water.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
Provided is a hair dye composition which suppresses dyeing affinity with skin, despite having sufficient dyeing affinity with hair. This hair dye composition includes: component A, namely HC blue 16; component B, namely at least one dye selected from the group consisting of basic brown 16 and basic brown 17; component C, namely at least one dye selected from the group consisting of HC yellow 4 and HC yellow 2; and component D, namely HC blue 2. It is preferable that the content of component A be 0.05-3.0 mass%, the content of component B be 0.05-1.0 mass%, the content of component C be 0.01-0.5 mass%, and the content of component D be 0.1-1.5 mass%.
Provided is a hair dye composition which suppresses dyeing affinity with skin, despite having sufficient dyeing affinity with hair. This hair dye composition includes: component A, namely basic blue 124; component B, namely at least one dye selected from the group consisting of basic orange 31, basic red 51, basic red 76, basic yellow 87, and basic yellow 57; component C, namely HC blue 2; and component D, namely at least one dye selected from the group consisting of HC yellow 4 and HC yellow 2. It is preferable that the content of component A be 0.005-0.5 mass%, the content of component B be 0.005-1.5 mass%, the content of component C be 0.1-1.5 mass%, and the content of component D be 0.01-0.5 mass%.
The purpose of the present invention is to provide a scalp care product which causes neither itching nor pain of the scalp even though used continuously and which can exert excellent hair growing and hair restoring effects. The scalp care product according to the present invention comprises: component A which is sphinganine; component B which is at least one member selected from among menthol, menthyl glyceryl ether and menthyl lactate; and component C which is pantothenyl alcohol. The scalp care product according to the present invention may further comprise component D which is polyoxyethylene-hardened castor oil.
The present invention relates to an emulsion cosmetic comprising a component A, a component B, a component C and a component D as mentioned below, wherein the content of the component A is 0.5 to 4.0% by mass, the sum total (B+C) of the content of the component B and the content of the component C is 0.5 to 6.0% by mass, and the ratio (B/(B+C)) of the content of the component B to the total content of the component B and the component C is 0.15 to 0.85 by mass: the component A: a phospholipid, the component B: glyceryl monobehenate, the component C: glyceryl monostearate, and the component D: water. The emulsion cosmetic according to the present invention can be used as a cosmetic, such as a milky lotion and a cream, which can impart a full-bodied sensation to the skin.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
The present invention pertains to a cosmetic composition containing components A-F below, wherein the mass ratio (B/A) of component B to component A is 5.5-18.0. Component A is a phospholipid, component B is a polyoxyethylene sterol ether having an average addition mole number of oxyethylene of 15-50 and/or a polyoxyethylene stanol ether having an average addition mole number of oxyethylene of 15 to 50, component C is a monovalent aliphatic alcohol having a branched chain of 12-24 carbon atoms, component D is at least one polyhydric alcohol selected from the group consisting of propylene glycol, dipropylene glycol, and 1,3-butylene glycol, component E is water, and component F is a ceramide and/or a sterol. This cosmetic composition can be used as-is as a cosmetic, or can be used as a formulation component in a skin lotion or the like.
The present invention pertains to an emulsified cosmetic containing component A, component B, component C, component D, and component E, wherein the content of component A is 0.2-3.5 mass%, the content of component B is 0.2-2.0 mass%, the content of component D is 0.3 mass% or less, the mass ratio (C/A) of component C to component A is 0.03-0.35, and the mass ratio (D/A) of component D to component A is 0.045 or more. Component A is an aluminum starch octenylsuccinate, component B is a glyceryl monobehenate, component C is a Xanthan gum, component D is a carboxyvinyl polymer and/or an alkyl-modified carboxyvinyl polymer, and component E is water. This emulsified cosmetic can be used as a cosmetic, such as a milky lotion or cream that can impart elasticity and a moisturized feeling to the skin.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
A method for observing the dynamics of sweat glands and a method for evaluating a substance of interest, which are useful for the development of a preparation for external application, such as a cosmetic. In each of the methods, an observation sample is used, which is prepared by staining all sweat glands, which are isolated alive, with a staining reagent and then holding the all sweat glands on a support using at least one material selected from the group consisting of collagen, agarose, a basement membrane matrix, poly-D-lysine and a membrane.
The present invention addresses the problem of providing a scrubbing agent, which gives an excellent feeling in using without any unpleasant skin irritation or discomfort feeling of foreign body, exerts an appropriate scrubbing effect and is eco-friendly, and a skin cleansing composition comprising the scrubbing agent. The scrubbing agent according to the present invention is characterized by comprising hydrocarbon wax particles, preferably hydrocarbon wax particles selected from the group consisting of petroleum-derived hydrocarbon wax particles and synthetic hydrocarbon wax particles. The skin cleansing composition according to the present invention is characterized by comprising the scrubbing agent.
Provided is a hair styling product composition having excellent stability of greasy character as well as minimal stickiness and excellent application properties and hair styling ability. The hair styling product composition pertaining to the present invention includes: a polyoxyethylene alkyl ether (component A) having a polyoxyethylene group, the average number of moles thereof added being 30 to 50, and having a cetyl group or a stearyl group; a polyoxyethylene alkyl ether (component B) having a polyoxyethylene group, the average number of moles thereof added being 5 to 25, and having a cetyl group or a stearyl group; and water (component C); and in the hair styling product composition pertaining to the present invention, the content of component A is 20.0 mass% to 35.0 mass%, and the content of component B is 3.0 mass% to 10.0 mass%.
Provided is a hairdressing composition which can sustain sufficient hairdressing performance and yet considerably prevent the occurrence of flaking. The hairdressing composition according to the present invention comprises silica (component A), a compound (component B) selected from the group consisting of polyoxyethylene cholesteryl ether and polyoxyethylene phytosterol, a clay mineral (component C) and a polysaccharide-type compound (component D), wherein the content of silica (component A) is 0.5-10.0 mass% inclusive.
The present invention addresses the problem of providing an oil-based cleansing cosmetic that sufficiently exhibits the advantageous cleansing effect of cleansing cosmetics while having remarkably excellent storage stability as a preparation. This oil-based cleansing cosmetic is characterized by comprising: a component (A), namely an oil agent selected from the group consisting of hydrocarbon oils and silicone oils; a component (B), namely glyceryl tribehenate; and a component (C), namely glyceryl behenate/eicosadioate. In addition, the oil-based cleansing cosmetic preferably contains a component (D), namely dipentaerythrityl tripolyhydroxystearate.
The purpose of the present invention is to provide: a warmth-imparting cosmetic that has good spreadability at the time of application, that does not feel sticky, that makes it possible to sufficiently impart an optimal feeling of warmth, and that washes off well; and a warmth-imparting cosmetic that has remarkably excellent storage stability as a preparation. This warmth-imparting cosmetic is characterized by comprising (A) a polyhydric alcohol, (B) a non-ionic surfactant having an HLB value of 8-16, (C) glyceryl tribehenate, and (D) glyceryl behenate/eicosadioate. The warmth-imparting cosmetic is also characterized by either not containing water or by containing water and having a water content of 1 mass% or less in 100 mass% of the cosmetic.
The purpose of the present invention is to provide: a warmth-imparting cleansing cosmetic that has good spreadability at the time of application, that does not feel sticky, that makes it possible to sufficiently impart an optimal feeling of warmth, and that has an excellent cleansing effect; and a warmth-imparting cleansing cosmetic that has remarkably excellent storage stability as a preparation. This warmth-imparting cleansing cosmetic is characterized by comprising (A) a polyhydric alcohol, (B) an oil agent selected from the group consisting of hydrocarbon oils and silicone oils, (C) glyceryl tribehenate, (D) glyceryl behenate/eicosadioate, and (E) lipophilic glyceryl monostearate. The warmth-imparting cleansing cosmetic is also characterized by either not containing water or by containing water and having a water content of 1 mass% or less in 100 mass% of the cosmetic.
A61K 8/39 - Derivatives containing from 2 to 10 oxyalkylene groups
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
The purpose of the present invention is to provide a composition for scalp, which, when applied onto scalp by a jet-spray mode, can exhibit improved impregnatability, attachability, dripping-preventing properties, anti-sticking properties and moisture-retaining properties on the scalp. The composition for scalp according to the present invention is packed in a jet-spray trigger container or a jet-spray pump container and is applied onto scalp by a jet-spray mode. The composition for scalp comprises a component A that is a diesterification product of a cyclohexanedicarboxylic acid and a polyoxyalkylene alkyl ether, a component B that is ethanol, a component C that is a polyhydric alcohol and a component D that is a thickening agent, and has a viscosity of 50 to 600 mPa·s inclusive at 25ºC.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
The present invention provides a body odor suppressing agent that contains activated carbon and that has excellent body odor suppressing effects, causes no black soiling on an object to be coated, and has excellent practical aptitude. The present invention also provides a body odor suppressing agent having an excellent feeling of use when the agent is applied to the skin. The present invention further provides a body odor suppressing agent capable of preventing nozzles from clogging when the agent is packed into a spray container and used. The body odor suppressing agent of the present invention includes a titanium oxide-coated activated carbon including an activated carbon having an average particle diameter of 15 to 50 μm and a titanium oxide present over the surface of the activated carbon.
The present invention relates to a foamy cosmetic material obtained by charging a stock liquid and a propellant in an aerosol container, wherein the stock liquid contains a powder selected from among the group consisting of a silicone-coated silica and a silica-coated silicone, and the content of the powder in the stock liquid is 5.0 mass% or more. According to the present invention, it is possible to provide a foamy cosmetic material which is an extremely fine and smooth foam and which exhibits excellent foam stability. According to the present invention, it is also possible to provide a foamy cosmetic material which does not cause stickiness and which can impart a dry and silky feeling.
An oily composition for the hair is provided which exhibits an excellent storage stability effect, has good spreadability on the palm of the hand and on the hair, has excellent finger-combability during styling, allows styling without being sticky, and leaves hair with separation after styling. This oily composition for the hair is characterized by containing a component (A): a hydrocarbon oil that is solid at room temperature and/or a wax that is solid at room temperature, a component (B): a tris (trimethylsiloxy)silyl propylcarbamic acid pullulan, a component (C): a volatile hydrocarbon oil, and a component (D): 12-hydroxystearic acid, and by containing substantially no water.
An oily composition for the hair is provided which exhibits an excellent storage stability effect, has good spreadability on the palm of the hand and on the hair, exhibits excellent hairstyling holding power, and does not result in stickiness after hairstyling. This oily composition for the hair is characterized by containing a component (A): a hydrocarbon oil that is solid at room temperature and/or a wax that is solid at room temperature, a component (B): a (norbornene/tris (trimethylsiloxy)silyl norbornene copolymer, a component (C): a volatile hydrocarbon oil, and a component (D): 12-hydroxystearic acid, and by containing substantially no water.
The present invention provides a cleansing lotion that is simple and capable of exhibiting superior effects in inhibition and improvement of skin roughness and/or acne and also provides a sheet cosmetic product containing the cleansing lotion. A cleansing lotion according to the present invention is used for an application selected from the group consisting of an application for sensitive skin, an application for acne prevention, and an application for acne improvement, and is characterized by containing an anti-inflammatory agent, a bactericidal agent, a fatty acid ester nonionic surface active agent, a moisturizing agent, and water. A sheet cosmetic product according to the present invention is characterized by comprising a sheet base material and the cleansing lotion with which the sheet base material is impregnated.
A liquid topical preparation for skin, containing component A: nylon powder, component B: bentonite and/or Laponite, component C: an organic salt and/or an inorganic salt, component D: a nonionic surfactant, and component E: water, the component A content being 0.5-5.0 mass%, the component B content being 0.4 mass% or less, the component C content being 0.1-3.0 mass%, and the mass ratio of the component A content to the component B content [(component A content)/(component B content)] being 100 or less. The liquid topical preparation for skin of the present invention can be used, for example, as a lotion.
The present invention provides an emulsified deodorant composition and a deodorant comprising the emulsified deodorant composition, in which, after being applied on an object, a germicide lasts dramatically longer on the object. The emulsified deodorant composition is characterized by containing: component A, a polyether-modified silicone; component B, a (dimethicone/vinyl dimethicone) cross-polymer; component C, 2–ethylhexyl palmitate; component D, an antiperspirant; component E, a germicide; and component F, water. The deodorant is characterized by comprising a container and the emulsified deodorant composition, wherein the container is filled with the emulsified deodorant composition.
A61K 8/894 - Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a polyoxyalkylene group, e.g. cetyl dimethicone copolyol
A61K 8/895 - Polysiloxanes containing silicon bound to unsaturated aliphatic groups, e.g. vinyl dimethicone
Provided is a wiping sheet that comprises a nonwoven fabric containing two kinds of cellulose fiber, and an impregnation liquid that is impregnated within the nonwoven fabric and contains water and ethanol, wherein the number of convexities and concavities of at least 40 µm, as measured by a surface test during wetting under pressure according to the KFX method, is in the range of 10–30, and the basis weight of the nonwoven fabric is 30–100 g/m2. When the wiping sheet is impregnated with a relatively high concentration of a lower alcohol, the wiping sheet exhibits a good liquid-retaining property and has an improved scrubbing feel and tension/springiness.
Provided is an oxidative hair dye that causes minimal scalp irritation and can reduce irritating odors during use, reduce damage to the scalp and hair, and sufficiently dye hair. This oxidative hair dye contains: a first agent, which includes (A) monoethanolamine or the like, (B) carbonate or the like, (C) ammonia, and (D) an oxidative dye; and a second agent, which includes (X) hydrogen peroxide. In the mixture of the first agent and the second agent, the content of (A) is 4.0–7.0 mass%, the content of (B) is 0.20–0.70 mmol/g, the total content of the ammonia and ammonium ions, in terms of ammonia, is 0.20–0.45 mmol/g, and the content of (X) is at least 1.5 mass% and less than 2.7 mass%.
Provided is an oxidative hair dye capable of reducing damage to hair, exhibiting excellent dyeing power, and having excellent storage stability. This oxidative hair dye comprises: a first agent including a component A being a compound selected from the group consisting of ammonia, monoethanolamine, diethanolamine, triethanolamine, and isopropanolamine, a component B being a compound selected from the group consisting of carbonate and hydrogen carbonate, a component C being dialkyl phosphate, a component D being a higher alcohol, and a component E being a oxidative dye; and a second agent including a component X being hydrogen peroxide. The component D content in the first agent is no more than 5.5% by mass and the component X content in a mixture of the first agent and the second agent is at least 1.5% by mass and less than 2.7% by mass.
The present invention provides a water-based cleansing cosmetic including a nonionic surfactant and a compound selected from the group consisting of ethanol, glycerin, diglycerin, polyethylene glycol, sorbitol, and mannitol, wherein the cleansing cosmetic has exceptional stability. The cleansing cosmetic of the present invention is characterized by including 50.0-98.0 mass% of water, 0.1-5.0 mass% of a polyoxyethylene/polyoxypropylene random copolymer having a number-average molecular weight of 10,000-20,000, 0.5-10.0 mass% of a nonionic surfactant, and 0.5-20.0 mass% of a compound selected from the group consisting of ethanol, glycerin, diglycerin, polyethylene glycol, sorbitol, and mannitol.
Provided is a hair styling composition that makes it possible to suppress the occurrence of flaking and stickiness when hair has been styled and to enhance the initial styling power for shaping the hair and the styling holding power after the hair has been shaped. This hair styling composition contains specific content amounts of: particles (component A) selected from the group consisting of silica, calcium carbonate, magnesium carbonate, hydroxyapatite, titanium oxide, zinc oxide, calcium silicate, magnesium silicate, aluminum silicate, and magnesium hydroxide; a compound (component B) selected from the group consisting of polyoxyethylene/polyoxypropylene random copolymers having a number-average molecular weight of from 10,000 to 20,000, and polyoxypropylene sorbitol having a number-average molecular weight of from 300 to 1,000; and an acrylic copolymer (component C) obtained by using diacetoneacrylamide as an essential monomer component.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
Provided is a hair styling product composition that exhibits excellent initial hair styling performance, stickiness, and wash-out performance. The hair styling composition comprises: 0.1-10 mass% of particles (a component (A)) that are selected from the group consisting of silica and the like; a specific sugar compound (a component (B)); a clay mineral (a component (C)); and a polymer (a component (D)) that is obtained using specific monomers and that is selected from the group consisting of a polymer (a component (D1)) that is obtained using two or more monomers that are selected from the group consisting of (meth)acrylic acid and (meth)acrylic acid alkyl esters and a polymer (a component (D2)) that is obtained using a monomer that is selected from the group consisting of (meth)acrylic acid and (meth)acrylic acid esters and a monomer that is selected from the group consisting of (meth)acrylic acid polyoxyethylene alkyl ethers, itaconic acid polyoxyethylene alkyl ethers, and vinyl neodecanoate.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
Provided is a hair styling product composition that exhibits excellent initial hair styling performance, that minimizes the occurrence of flaking and stickiness, that gathers hair together in a supple manner, that maintains styled hair, and that makes it possible to improve the washing out thereof after hair styling. The hair styling product composition comprises: 0.1-10 mass% of particles that are selected from the group consisting of silica, calcium carbonate, magnesium carbonate, hydroxyapatite, titanium oxide, zinc oxide, calcium silicate, magnesium silicate, aluminum silicate, and magnesium hydroxide; a compound that is selected from the group consisting of monosaccharides, disaccharides, and sugar alcohols; polyethylene glycol that has a number average molecular weight of 150-450; polyethylene glycol that has a number average molecular weight of 550-2,000; and polyethylene glycol that has a number average molecular weight of 2,500-4,000.
Provided are a deodorant composition and a deodorant agent using the deodorant composition, allowing for a dramatic increase in the persistence of disinfectant on the application subject, after application. This deodorant composition contains ethanol, the disinfectant, a hydrophobized hydroxyalkyl cellulose, and an ester compound having a molecular weight of 150 or greater. This deodorant agent comprises a container and the deodorant composition filled into the container.
The present invention relates to a deodorant or a refreshing cosmetic material, characterized by including polyurethane particles (component (A)), an anionic polymer (component (B)), ethanol (component (C)), and water (component (D)), wherein the content of component (B) is 0.0001 to 0.008 mass%; the content of component (C) is 30.0 to 70.0 mass%; and the content of component (D) is 20.0 to 69.0 mass%. The main effect of the deodorant or refreshing cosmetic material according to the present invention is that the caking of polyurethane particles is prevented, hence allowing for easy redispersion, despite the deodorant or refreshing cosmetic material containing polyurethane particles and having water and ethanol as dispersion media.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
Provided is a hair styling product composition that increases storage stability by minimizing the sedimentation of a powder during long-term storage or by minimizing the loss of water from and separation of a composition. The hair styling product composition also makes it possible to increase spreadability and conformability by minimizing increases in viscosity at the time of application. The hair styling product composition comprises: particles (a component (A)) that are selected from the group consisting of silica, calcium carbonate, magnesium carbonate, hydroxyapatite, titanium oxide, zinc oxide, calcium silicate, magnesium silicate, aluminum silicate, and magnesium hydroxide; a compound (a component (B)) that is selected from the group consisting of monosaccharides, disaccharides, and sugar alcohols; a clay mineral (a component (C)); and a polysaccharide compound (a component (D)). In the hair styling product composition, the component (A) content is 0.1-10 mass% and the mass ratio of the component (C) content and the component (D) content is 2:1 to 10:1.
