Goods & Services

Logiciels; logiciels dans le domaine medical; logiciels de santé visant à optimiser le rendement en plaquettes lors de la production de concentrés plaquettaires à partir de la couche leuco-plaquettaire; appareils de laboratoire pour le prélèvement et le traitement du sang. Services scientifiques et technologiques ainsi que services de recherches et de conception y relatifs dans le domaine médical, à savoir le domaine du traitement du sang, le domaine de la conservation du sang, des composants sanguins, des organes, des cellules et des tissus, le domaine des masques de protection respiratoire, le domaine des solutions injectables médicamenteuses et non médicamenteuses; élaboration, développement, conception, maintenance, configuration, mise à jour de logiciels; élaboration, développement, conception, maintenance, mise à jour de logiciels dans le domaine médical; élaboration, développement, conception, maintenance, mise à jour de logiciels de santé visant à optimiser le rendement en plaquettes lors de la production de concentrés plaquettaires à partir de la couche leuco-plaquettaire.

Goods & Services

Laboratory apparatus for treating blood; Laboratory apparatus for sampling blood; Automatic laboratory agitators for sampling blood; Laboratory apparatus for the separation of blood into blood components including plasma, platelets and red blood cells; Laboratory centrifuges for the separation of blood into blood components including plasma, platelets and red blood cells; Apparatus and instruments for the automatic preparation of blood components; Laboratory welding machines for tubes of plastic; Laboratory welding machines for blood bag tubes; Laboratory high-frequency welding machines for tubes of plastic. Medical devices, instruments, apparatus and equipment for the withdrawal, collection, storage, treatment, analysis, sampling, filtering, separation and/or administration of blood, blood components; Blood donation monitor; Blood transfusion apparatus; Blood transfusion devices; Sampling containers for medical use; Syringes and syringe needles for medical use; Medical catheters for blood transfusion; Tube connectors for medical use; Clips for medical tubing; Pressure regulators, flow controllers, pressure sensors, blood sampling devices for medical purposes; Pumps for medical purposes; Collection bags for medical purposes; Filters for blood or blood components for medical purposes; Lighting machines for reducing pathogens of the blood and transfusion devices for reducing pathogens of the blood (medical apparatus); Machines for separating blood into blood components (medical apparatus); Medical welding machines for tubes of plastic; Medical welding machines for blood bag tubes; Medical high frequency welding machines for tubes of plastic; Blood collection instruments; Blood sample collection instruments; Blood testing instruments; blood collectors; Medical instruments and apparatus for platelet collection; Filters for blood and blood components for medical use (for blood transfusion); Filters for blood and blood components for medical use (for removing white blood cells for the purposes of transfusion); Filters for blood and blood components for medical use (for removing pathogens for transfusion purposes); Filters for blood and blood components for medical use (for removing prions for transfusion purposes); Blood bags for medical purposes (medical instruments and apparatus); chairs for medical use; Armchairs for medical purposes. Technical consultancy in the field of processes for the withdrawal, collection, storage, treatment, analysis, sampling, filtering, separation and/or administration of blood, blood components.

Abstract

The invention relates to a medical device (1) that consists of a needle (2) mounted in a hub (3) and case (6) that presents a receptacle (7) in which the previously mentioned needle is positioned, this case being held on the hub (3) by means of a ring (8) that is held immobile axially around a proximal range (9a) of the hub by forming between them a proximal interface (10a) designed to ensure rotational solidarization of the hub (3) / ring (8) assembly, this ring presenting a distal edge that is connected to a proximal edge of the case (6) by means of a crown of material (17) designed to be severed by the relative rotation between the case (6) and the hub (3) / ring (8) assembly with a view to being able to use the needle (2), with the receptacle (7) being sealed by a combination of the proximal interface (10a) and the crown (17), which is continuous.

IPC Classes  ?

• A61M 5/158 - Needles
• A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
• A61M 5/50 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile

Goods & Services

Pharmaceutical products such as solutions for treating blood and blood components; bags containing the origin of blood treatment solutions; none of the aforesaid goods being preparations for treating colds or flu. Medical devices for blood treatment; associated medical kits comprised of equipment, such as filters, pouches, and pipes, for blood plasma treatment and purification; parts and components of all the aforesaid devices.

Goods & Services

Pharmaceutical products such as solutions for treating blood and blood components; bags containing the origin of blood treatment solutions; none of the aforesaid goods being preparations for treating colds or flu. Medical devices for blood treatment; associated medical kits comprised of equipment, such as filters, pouches, and pipes, for blood plasma treatment and purification; parts and components of all the aforesaid devices.

Goods & Services

Pharmaceutical and veterinary products; sanitary products for medicine; dietetic substances for medical use; infusion solutions for medical use such as electrolyte, saline, medicated, dextrose, Ringer's lactate, mannitol solutions; rinsing solutions for medical use; solutions for fluid replacement and blood replacement for medical use; blood preservation solutions, blood components; products, substances and solutions or media for the collection, preservation, storage, treatment, nutrition, culture, freezing, thawing, washing, reinjection, processing, transplantation of biological cells, organs and tissues; disinfectants, preparations for enteral and parenteral nutrition, all these goods pertaining to the licensed pharmacy trade. Protective respiratory masks for industrial use; software based on RFID technology for encoding, identifying, tracking and monitoring data relating to blood, blood components and/or pharmaceuticals; laboratory apparatus for blood treatment; laboratory apparatus for blood sampling; automatic laboratory stirrers for blood sampling; laboratory apparatus for separating a composite biological fluid into one or more components; laboratory apparatus for separating blood into blood components such as plasma, platelets and red blood cells; laboratory centrifuges for separating a biological fluid into one or more components; laboratory centrifuges for separating blood into blood components such as plasma, platelets and red blood cells; parts and constituent parts of the aforesaid apparatus and centrifuges; laboratory instruments, such as radiation-emitting apparatus for the analysis of biological fluids, radiation devices for the treatment of body fluids; apparatus and instruments for automatic preparation of blood components; laboratory welders for plastic tubes; laboratory welders for blood bag tubes; high-frequency laboratory welders for plastic tubes. Medical devices for taking of samples, collecting, storing, treating, analyzing, sampling, filtering, separating and/or delivering of blood, blood compounds, biological cells, organs and/or tissues; transfusion devices for medical use; containers for taking samples for medical use; dropper devices for medical use (droppers, dropper bottles); syringes and needles for syringes for medical use; containers and apparatus for the delivery of enteral and parenteral solutions for medical use; catheters of all kinds; connectors for tubes for medical use, clips for tubes for medical use; injection sites for medical use; needleless connectors, needleless ports, needleless injection sites for medical use, medical valves; pressure regulators, flow controllers, pressure sensors, blood sampling devices for medical use; pumps for medical use, collection bags for medical use; filters for blood or blood constituents for medical use; medical fluid delivery apparatus; face masks for medical use; protective respiratory masks for medical use; illumination machines for reducing blood pathogens and transfusion devices for reducing blood pathogens (medical apparatus); machine for separating blood into blood components (medical apparatus); welders for medical use for plastic tubes; welders for medical use for blood bag tubes; high-frequency welders for medical use for plastic tubes; parts and components for all the aforesaid goods. Scientific and technological services as well as research and design services relating thereto in the medical field, namely, the field of blood treatment, the field of the preservation of blood, blood components, organs, cells and tissues, in the field of protective respiratory masks, the field of medicated and non-medicated injectable solutions. Medical services for the collection, preservation, storage, treatment, nutrition, culture, freezing, thawing, washing, reinjection, processing and transplantation of biological cells, organs and tissues.

Abstract

The invention relates to a method for selectively removing leukocytes and erythrocytes from a platelet-concentrated product, the method comprising passing a platelet-concentrated and leukocyte-depleted product through a porous element which is a barrier to erythrocytes, the porous element which is a barrier to erythrocytes comprising at least one porous membrane made of a hydrophilic material, the pores of the membrane having a nominal size of between 1 μm and 4 μm, and an absolute pore size of between 2 μm and 5 μm.

IPC Classes  ?

• A61K 35/16 - Blood plasmaBlood serum
• A61K 35/19 - PlateletsMegacaryocytes
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
• B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties

IPC Classes  ?

• A61K 35/19 - PlateletsMegacaryocytes
• A61M 1/02 - Blood transfusion apparatus
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation

Abstract

The invention relates to a method for obtaining a product having an increased blood platelet concentration and a reduced anti-A and/or anti-B antibody content, said method comprising: - assembling one or more leukocyte/platelet layers obtained by centrifugation of whole blood, - bringing said assembly into contact with a set of particles capable of binding anti-A and/or anti-B antibodies, for a time sufficient to bind anti-A and/or anti-B antibodies to said particles, so as to obtain a mixture of assembly of leukocyte/platelet layers and of particles bound or not bound to anti-A and/or anti-B antibodies, - separating said mixture by centrifugation, so as to obtain a pellet comprising red blood cells and particles bound or not bound to anti-A and/or anti-B antibodies, and a supernatant of a product having an increased platelet concentration and a reduced anti-A and/or anti-B antibody content, and - extracting said thus separated product having an increased platelet concentration and a reduced anti-A and/or anti-B antibody content.

IPC Classes  ?

• A61K 35/19 - PlateletsMegacaryocytes
• A61M 1/02 - Blood transfusion apparatus
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• B01D 61/00 - Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltrationApparatus, accessories or auxiliary operations specially adapted therefor
• C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor

Goods & Services

(1) Produits pharmaceutiques tels que solutions destinées au traitement du sang et de composants sanguins; sacs contenant à l'origine des solutions pour le traitement du sang; aucun des produits précités n'étant des préparations pour le traitement des rhumes ou de la grippe. (2) Dispositifs médicaux pour traitement du sang; kits médicaux connexes composés des équipements, tels que filtres, poches et tuyaux, permettant le traitement et la purification du plasma sanguin; pièces et parties constitutives de tous les dispositifs précités.

Goods & Services

Cell culture media being cell culture substances and cell culture solutions for the collection, preservation, storage, processing, nutrition, culture, freezing, thawing, washing, reinjection, transformation and transplantation of biological cells, organs and tissues, all the foregoing for research and medical research use; cell growth media being cell growth substances and cell growth solutions for the collection, preservation, storage, processing, nutrition, culture, freezing, thawing, washing, reinjection, transformation and transplantation of biological cells, organs and tissues, all the foregoing for research and medical research use Pharmaceutical products for the treatment of viral and infectious diseases, and veterinary products in the nature of dietary supplements for animals; hygienic products for medicine, namely, antibacterial soap for medical use; dietetic substances in the nature of dietic foods, dietic beverages, and dietic infusions adapted for medical use; infusion solutions for medical use, namely, electrolytes for medical use, saline solution for medical purpose, dextrose solution for medical purposes, sugar based solutions for medical purposes, sugar substitute solutions for medical purposes; medical rinsing solutions, namely, saline solutions and saline wash for medical use; fluid replacement and blood replacement solutions, namely, electrolytes for medical use, saline solution for medical purposes, dextrose solution for medical purpose, sugar based solutions for medical purposes, sugar substitute solutions for medical purposes; anticoagulant solutions for the storage of blood and blood components disinfectants for cleaning pharmaceutical laboratories; enteral and parenteral nutritional supplement preparations, all being pharmaceutically made Medical electric welding machines used with laboratory plastic tubes, blood bag tubes; medical high-frequency laboratory electric welders for plastic tubes, blood bag tubes; parts and components for all the aforementioned products Respiratory protection masks for industrial use; downloadable data processing software based on RFID technology for coding, identifying, tracking and controlling data relating to blood, blood components and pharmaceutical products; laboratory equipment for blood processing, namely, test tubes; laboratory equipment for blood collection, namely, scientific research specimen collection devices in the nature of tubes, swabs, bags, for the collection of blood; laboratory equipment for blood processing, namely, laboratory centrifuges; automatic laboratory shakers being automatic laboratory centrifuges for blood collection; laboratory equipment for separating a composite biological fluid into one or more components, namely, a laboratory centrifuge; laboratory equipment for separating blood into blood components such as plasma, platelets and red blood cells, namely, a laboratory centrifuge; laboratory centrifuges for separating a biological fluid into one or more components; laboratory centrifuges for the separation of blood into blood components such as plasma, platelets and red blood cells; parts and components of the aforementioned apparatus and centrifuges; laboratory instruments, namely, a radiation-emitting electronic apparatus for the analysis of biological fluids; laboratory electronic radiation devices for the treatment processing of body fluids for research use; apparatus and instruments for the automatic preparation of blood components, namely, laboratory centrifuges ; research storage product, namely, petri dishes for the collection, preservation, storage, processing, culture, freezing, thawing, washing, reinjection, transformation and transplantation of biological cells, organs and tissues Medical specimen collection devices in the nature of glass slides, cup, bags for the collection and storage, of blood, blood compounds, biological cells, organs and tissues; transfusion device sets for medical use; withdrawal medical waste containers for medical use; dropper devices for medical use, namely, droppers for administering medication, sold empty, dropper bottles for administering medication, sold empty, eye droppers for medical purposes; syringes and needles for syringes for medical use; dosage dispenser containers and dosage dispenser apparatus containers for administering enteral and parenteral solutions to patients for medical use; catheters of all kinds; connectors for drainage tubes, connectors for transfusion tubes, and connectors for tubes for administering drugs, all the foregoing for medical use, clips being clamps for tubes for medical and surgical use; injection sites being a medical port for medical use; needleless medical connectors to connect intravenous (IV) catheters, administration sets, and syringes, without the use of a needle ; medical needleless ports, needleless injection sites being port devices for medical use, medical valves being cardiac valves for surgical procedures; apparatus for taking blood samples consisting of medical pressure regulators, flow controllers, pressure transducers, for medical use ; pumps for medical use, namely, infusion pumps for delivering measured amounts of solutions into the bloodstream over time ; sampling bags for medical use, namely, blood collection bags for medical purposes; filters for blood or blood components for medical use; medical fluid administration devices, namely fluid warmers for the intravenous administration of fluids; face masks for medical use; respiratory protection masks for medical use; medical illumination machines being a pathogen reduction technology system for the reduction of blood pathogens and transfusion set medical devices for the reduction of blood pathogens; machine for the separation of blood into blood components for medical purposes Pet restraining devices consisting of harnesses and/or restraining straps, for use in veterinary care Scientific and technological services as well as research and design services all the foregoing in the medical field, and in the fields of blood processing, conservation of blood, blood components, organs, cells and tissues, the field of respiratory protection masks, the field of medicinal and non-medicinal injectable solutions; online, non- downloadable data processing software based on RFID technology for coding, identifying, tracking and controlling data relating to blood, blood components and pharmaceutical products Medical services, namely, medical laboratory analysis services featuring the collection, preservation, storage, processing, nutrition, cultivation, freezing, thawing, washing, reinjection, transformation and transplantation of biological cells, organs and tissues, all the foregoing relating to the treatment of persons

Goods & Services

Pharmaceutical products such as solutions for use in connection with the processing of blood and blood components; bags which initially contain solutions for processing blood; none of the foregoing being preparation for the treatment of colds or influenza. Medical devices for treating blood; Related medical kits; Parts and fittings for the aforesaid devices.

Goods & Services

Pharmaceutical products such as solutions for use in connection with the processing of blood and blood components; bags which initially contain solutions for processing blood; none of the foregoing being preparation for the treatment of colds or influenza. Medical devices for treating blood; Related medical kits; Parts and fittings for the aforesaid devices.

Goods & Services

Pharmaceutical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic substances adapted for medical use; Perfusion solutions for medical purposes, including electrolyte, saline, medicated, dextrose, Ringer lactate solutions, mannitol solutions; Rinsing solutions for medical purposes; Solutions for temporary fluid replacement and for blood replacement, for medical purposes; Solutions for preserving blood, blood components; Preparations, substances and solutions or media for collecting, preserving, storing, treating, feeding, growing, freezing, thawing, washing, reinjecting, processing, transplanting biological cells, organs and tissues; Disinfectants, Preparations for enteral and parenteral feeding, All the aforesaid materials and preparations falling under the pharmaceutical monopoly. Protective respiratory masks for industrial purposes; RFID-based computer software for coding, identifying, monitoring and controlling data relating to blood, blood components and/or pharmaceutical preparations; Laboratory apparatus for treating blood; Laboratory apparatus for sampling blood; Automatic laboratory agitators for sampling blood; Laboratory apparatus for the separation of composite biological fluids into one or more components; Laboratory apparatus for the separation of blood into blood components including plasma, platelets and red blood cells; Laboratory centrifuges for the separation of biological fluids into one or more components; Laboratory centrifuges for the separation of blood into blood components including plasma, platelets and red blood cells; Parts and components for the aforesaid apparatus and centrifuges; Laboratory instruments, For example: Apparatus emitting radiation for analysing biological fluids, radiation devices for the treatment of bodily fluids; Apparatus and instruments for the automatic preparation of blood components; Laboratory welding machines for tubes of plastic; Laboratory welding machines for blood bag tubes; Laboratory high-frequency welding machines for tubes of plastic. Medical devices for the withdrawal, collection, storage, processing, analysis, sampling, filtering, separation and/or administration of blood, blood components, biological cells, organs and/or tissues; Transfusion devices for medical purposes; Sampling containers for medical use; Dropper devices for medical purposes (droppers, dropper bottles); Syringes and syringe needles for medical use; Containers and apparatus for administering enteral and parenteral solutions, for medical purposes; Catheters of all kinds; Connectors for tubes for medical use, fastenings for tubes for medical use; Injection sites for medical purposes; Needleless connectors, needleless ports, needleless injection sites for medical purposes, Medical valves; Pressure regulators, flow controllers, pressure sensors, blood sampling devices for medical purposes; Pumps for medical purposes, Collection bags both for medical purposes; Filters for blood or blood components for medical purposes; Medical fluid administration equipment; Face masks for medical purposes; Protective respiratory masks for medical purposes; Lighting machines for reducing pathogens of the blood and transfusion devices for reducing pathogens of the blood (medical apparatus); Machines for separating blood into blood components (medical apparatus); Medical welding machines for tubes of plastic; Medical welding machines for blood bag tubes; Medical high frequency welding machines for tubes of plastic; Parts and fittings for all the aforesaid goods. Scientific and technological services and research and design relating thereto in the field of medicine, namely the field of blood processing, the field of blood preservation, blood component preservation, organ preservation, cell and tissue preservation, the field of protective respiratory masks, the field of injectable medicated and non-medicated solutions. Medical services for the collection, preservation, storage, treatment, nutrition, culture, freezing, thawing, washing, reinjection, transformation and transplantation of biological cells, organs and tissues.

Abstract

Dispositif pour souder un tube souple.
L'invention concerne un dispositif (1) pour souder un tube souple par
radiofréquence
comprenant :
- un organe de pincement (2) comprenant une tête de soudage formée d'une
première électrode (3) et d'une deuxième électrode (4),
- une source d'énergie configurée pour alimenter en énergie électrique le
dispositif à
souder, et
- un organe de soudure comprenant un générateur de radiofréquence et un
convertisseur d'énergie radiofréquence, lesdites première et deuxième
électrodes
(3,4), ladite source d'énergie, ledit générateur de radiofréquence et ledit
convertisseur d'énergie formant entre eux un circuit électrique ayant une
impédance,
ledit convertisseur d'énergie comprenant au moins deux inducteurs montés en
série
avec la première et deuxième électrode (3,4) de l'organe de soudure et un
élément
de contrôle du passage de courant électrique configure pour couper le passage
dudit
courant électrique dans l'un des inducteurs de sorte à maintenir constante
l'impédance du circuit électrique pendant la soudure.

IPC Classes  ?

• B29C 65/04 - Dielectric heating, e.g. high-frequency welding

Abstract

The invention relates to an apparatus (21) for the treatment, by electromagnetic irradiation at a predetermined dose, of a biological fluid contained in an irradiation receptacle, the irradiation receptacle having at least one wall which is permeable to the electromagnetic radiation. The apparatus comprises: a recess (22) which is configured to receive the irradiation receptacle (22) containing the biological fluid; one or more light sources which emit the electromagnetic radiation; an information collection device (34) which is configured to collect information regarding a parameter of the irradiation receptacle; and a control unit which is configured to: (i) obtain information regarding a parameter of the irradiation receptacle; (ii) determine a target irradiation dose on the basis of the information regarding the parameter and the predetermined dose; and (iii) irradiate the irradiation receptacle with the target irradiation dose, the information regarding the parameter of the irradiation receptacle comprising the transmittance value of the wall of the irradiation receptacle.

IPC Classes  ?

• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61J 1/10 - Bag-type containers
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
• A61K 41/17 - Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
• A61M 1/02 - Blood transfusion apparatus
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation

IPC Classes  ?

• A61J 1/10 - Bag-type containers
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
• A61K 41/17 - Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61M 1/02 - Blood transfusion apparatus
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation

Abstract

The invention relates to a pouch system (1) for the treatment of a biological fluid by electromagnetic irradiation, said pouch system comprising at least one element consisting of an irradiation pouch (2) intended to contain the biological fluid to be irradiated, said irradiation pouch (2) being made of a material that is permeable to said electromagnetic radiation, said pouch system (1) further comprising at least one protective film (26a, 26b) covering said irradiation pouch (2), said protective film (26a, 26b) being made of a gas-barrier polymer material having a permeability to oxygen of less than or equal to 100 cm3/m2/24 h at a temperature of 23°C and relative humidity of 50%.

IPC Classes  ?

• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61J 1/10 - Bag-type containers
• A61K 41/17 - Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• A61M 1/02 - Blood transfusion apparatus

IPC Classes  ?

• A61J 1/10 - Bag-type containers
• A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
• A61K 41/17 - Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61M 1/02 - Blood transfusion apparatus
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation

Abstract

The invention relates to a pouch system (1) for the treatment of a biological fluid by electromagnetic irradiation, said pouch system comprising at least one element consisting of an irradiation pouch (2) intended to contain the biological fluid to be irradiated, said irradiation pouch (2) being made of a material that is permeable to said electromagnetic radiation, said pouch system (1) further comprising at least one protective film (26a, 26b) covering said irradiation pouch (2), said protective film (26a, 26b) being made of a gas-barrier polymer material having a permeability to oxygen of less than or equal to 100 cm3/m2/24 h at a temperature of 23°C and relative humidity of 50%.

IPC Classes  ?

• A61J 1/10 - Bag-type containers
• A61K 41/17 - Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61M 1/02 - Blood transfusion apparatus
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation

Abstract

The invention relates to a pouch system (1) for treating a biological fluid by electromagnetic irradiation, the pouch system comprising at least one element consisting of an irradiation pouch (2) intended to contain the biological fluid to be irradiated, the irradiation pouch (2) being made of a material that is permeable to the electromagnetic radiation, the pouch system further comprising one or more other elements made of one or more materials formulated without phthalates or terephthalates.

IPC Classes  ?

• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61J 1/10 - Bag-type containers
• A61K 41/17 - Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• A61M 1/02 - Blood transfusion apparatus
• A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor

Goods & Services

Laboratory welding machines for tubes of plastic or Laboratory welding machines for bags of plastic; Laboratory welding machines for blood tube and bag systems; Laboratory high-frequency welding machines for tubes of plastic or Laboratory high-frequency welding machines for bags of plastic; Laboratory welding equipment and apparatus for hermetically sealing tubes or bags of plastic. Medical welding machines for tubes of plastic or Medical welding machines for bags of plastic; Medical welding machines for blood tube and bag systems; Medical high frequency welding machines for tubes of plastic or Medical high-frequency welding machines for bags of plastic; Medical devices for hermetically sealing tubes or bags of plastic.

Abstract

A method and system for producing apoptotic mononuclear cells. The invention relates to a method for producing apoptotic mononuclear cells contained in a fraction of peripheral blood from a donor, said method comprising the step consisting in subjecting said blood fraction to ultraviolet irradiation having a wavelength of between 200 nm and 320 nm, wherein said irradiation is arranged to induce a difference between the degree of apoptosis of the irradiated cells and that of the non-irradiated cells of greater than 15%, 48 hours after the irradiation, so as to obtain apoptotic mononuclear cells capable of modulating the immune response in a patient.

IPC Classes  ?

• C02F 1/32 - Treatment of water, waste water, or sewage by irradiation with ultraviolet light
• A61K 35/17 - LymphocytesB-cellsT-cellsNatural killer cellsInterferon-activated or cytokine-activated lymphocytes
• A61K 35/15 - Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cellsMyeloid precursor cellsAntigen-presenting cells, e.g. dendritic cells
• A61L 2/10 - Ultraviolet radiation
• A61L 9/20 - Ultraviolet radiation
• A61P 37/00 - Drugs for immunological or allergic disorders
• A61P 37/06 - Immunosuppressants, e.g. drugs for graft rejection
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers

Abstract

The invention relates to a filtration unit (1) for enabling the selective leucocytapheresis of a fluid containing blood platelets, comprising an external pouch provided with at least one inlet orifice (2) and at least one outlet orifice (3), the pouch enclosing a porous element (4) interposed between said orifices, the porous element enclosing a leucocytapheresis medium impregnated with a polymer, the polymer having the general formula -(A)m-(B)n- (I), wherein A is a unit originating from an alkoxyalkyl acrylate or alkoxyalkyl methacrylate monomer, B is a unit originating from a hydrophobic polymerisable monomer, and m and n are integers, the sum of which, m+n, is equal to 100, m being an integer greater than 80.

IPC Classes  ?

• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• A61M 1/38 - Removing constituents from donor blood and returning remainder to body
• A61M 1/02 - Blood transfusion apparatus
• B01D 39/14 - Other self-supporting filtering material

Abstract

The invention relates to a device (24) for welding a portion of a flexible container (2), the device (24) comprising: - a tray (25) for receiving the container to be welded (2), - a welding device (26) configured to switch from one of the following states to the other: an open state wherein the portion of the container (2) to be welded is placed in the welding device (26) without being clamped, a clamping state wherein the portion of the container (2) to be welded is clamped, and a welding state which comes after the clamping state wherein the portion of the container (2) to be welded is welded, and - an actuating device (27) configured to actuate the welding device (26) at least from the clamping state to the open state without passing through the welding state and from the clamping state to the welding state.

IPC Classes  ?

• B29C 65/02 - Joining of preformed partsApparatus therefor by heating, with or without pressure
• B29C 65/04 - Dielectric heating, e.g. high-frequency welding
• B29C 65/08 - Joining of preformed partsApparatus therefor by heating, with or without pressure using ultrasonic vibrations
• B29C 65/14 - Joining of preformed partsApparatus therefor by heating, with or without pressure using wave energy or particle radiation
• B29C 65/18 - Joining of preformed partsApparatus therefor by heating, with or without pressure using heated tool

Goods & Services

Pharmaceutical and veterinary preparations; Pharmaceutical products for the treatment of joint disease; Intra-articular injectable pharmaceuticals, including based on hyaluronic acid for the treatment of joint diseases; Hyaluronic acid for medical use for the treatment of joint diseases; Intra-articular injectable pharmaceuticals based on platelet-rich plasma for the treatment of joint diseases; Pain relief medications and anti-inflammatory drugs; Joint lavage solutions; Sanitary preparations for medical purposes; Dietetic substances adapted for medical use; Disinfectants; Rinsing solutions for medical purposes; Preparations for enteral and parenteral feeding; Solutions for temporary fluid replacement and for blood replacement, for medical purposes; Solutions for preserving blood, blood components, organs and/or tissues. Protective respiratory masks for industrial purposes; RFID-based computer software for coding, identifying, monitoring and controlling data relating to blood, blood components and/or pharmaceutical preparations; Laboratory apparatus for treating blood; Laboratory apparatus for sampling blood; Automatic laboratory agitators for sampling blood; Laboratory apparatus for the separation of composite biological fluids into one or more components; Laboratory apparatus for the separation of blood into blood components including plasma, platelets and red blood cells; Laboratory centrifuges for the separation of biological fluids into one or more components; Laboratory centrifuges for the separation of blood into blood components including plasma, platelets and red blood cells; Parts and components for the aforesaid apparatus and centrifuges; Laboratory instruments, For example: Apparatus emitting radiation for analysing biological fluids, radiation devices for the treatment of bodily fluids; Apparatus and instruments for the automatic preparation of blood components; Laboratory welding machines for tubes of plastic; Laboratory welding machines for blood bag tubes; Laboratory high-frequency welding machines for tubes of plastic; Electronic databases containing information relating to joint disease diagnosis and treatment; Computer hardware, computers, software, computer peripheral devices and electronic instruments for receiving, processing, reproducing, transmitting and storing clinical and medical data, medical and clinical sounds and images relating to joint disease diagnosis and treatment. Medical devices for the withdrawal, collection, storage, processing, analysis, sampling, filtering, separation and/or administration of blood, blood components, biological cells, organs and/or tissues; Transfusion devices for medical purposes; Sampling containers for medical use; Dropper devices for medical purposes (droppers, dropper bottles); Syringes and syringe needles for medical use; Syringes and sets for intra-articular injection; Containers and apparatus for administering enteral and parenteral solutions, for medical purposes; Catheters of all kinds; Connectors for tubes for medical use, fastenings for tubes for medical use; Injection sites for medical purposes; Needleless connectors, needleless ports, needleless injection sites for medical purposes, Medical valves; Pressure regulators, flow controllers, pressure sensors, blood sampling devices for medical purposes; Pumps for medical purposes, Collection bags both for medical purposes; Filters for blood or blood components for medical purposes; Medical fluid administration equipment; Face masks for medical purposes; Protective respiratory masks for medical purposes; Lighting machines for reducing pathogens of the blood and transfusion devices for reducing pathogens of the blood (medical apparatus); Machines for separating blood into blood components (medical apparatus); Medical welding machines for tubes of plastic; Medical welding machines for blood bag tubes; Medical high frequency welding machines for tubes of plastic; Medicated preparation kits containing platelet-rich plasma for the treatment of joint diseases; Walking sticks for medical purposes; Clothing, headgear and footwear, braces and supports, for medical purposes; Medical apparatus for diagnosing orthopaedic disorders and for rehabilitation; Compression garments; Orthopaedic soles; Orthopaedic footwear; Gloves for medical purposes; Compression gloves for pain relief; Orthopaedic splints; Knee crutches; Treadmills for medical use in physiotherapeutic exercise; Parts and fittings for all the aforesaid goods; All the aforesaid goods not being for use in surgical robotics, surgical guidance or implants.

Abstract

The invention relates to a system for treating a biological fluid such as blood or a blood component, by selective removal of a target substance, comprising a treatment bag (2) provided with at least one inlet opening (3) and at least one outlet opening (4), the treatment bag containing an assembly of particles (5) having an affinity for the target substance, the assembly comprising small particles having a size less than 15 pm, the system further comprising a barrier means (6) formed of at least one porous membrane made of a hydrophilic material, the pores of the membrane being calibrated at a size capable of preventing the passage of the small particles, namely less than 3 pm.

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus

Abstract

The invention relates to a system for treating a biological fluid such as blood or a blood component, by selective removal of a target substance, comprising a treatment bag (2) provided with at least one inlet opening (3) and at least one outlet opening (4), the treatment bag containing an assembly of particles (5) having an affinity for the target substance, the assembly comprising small particles having a size less than 15 pm, the system further comprising a barrier means (6) formed of at least one porous membrane made of a hydrophilic material, the pores of the membrane being calibrated at a size capable of preventing the passage of the small particles, namely less than 3 pm.

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus

Goods & Services

Laboratory equipment and apparatus, namely, separating and welding devices for connecting tubes of plastic material; equipment and apparatus for sterile connection of tubes of plastic material (laboratory apparatus and instruments). Medical devices, namely separating and welding devices for connecting tubes of plastic material; medical devices for sterile connection of tubes of plastic material.

Abstract

The invention relates to a filtration unit (1) intended to allow the leucocytapheresis of the blood or of a blood product, comprising an external pouch (2) provided with at least one inlet orifice (3) and with at least one outlet orifice (4), the pouch containing a porous element interposed between said orifices, said porous element comprising at least one leucocytapheresis medium (8) that works by adsorbing and/or by filtering out the leucocytes, and at least one layer of nonwoven (7) provided with a plurality of bumps, each of the bumps having a perforation passing through it in the heightwise direction to form a relief-perforated nonwoven layer.

IPC Classes  ?

• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• A61M 1/02 - Blood transfusion apparatus
• B01D 39/16 - Other self-supporting filtering material of organic material, e.g. synthetic fibres
• B01D 39/18 - Other self-supporting filtering material of organic material, e.g. synthetic fibres the material being cellulose or derivatives thereof
• D04H 1/485 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties the fleeces or layers being consolidated by mechanical means, e.g. by rolling by needling or like operations to cause entanglement of fibres in combination with at least one other method of consolidation in combination with weld-bonding
• D04H 1/54 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties by welding together the fibres, e.g. by partially melting or dissolving
• D04H 1/72 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres characterised by the method of forming fleeces or layers, e.g. reorientation of fibres the fibres being randomly arranged

Goods & Services

(1) Équipements et appareils de laboratoire, nommément soudeuses pour raccorder des tubes de laboratoire en matière plastique; équipement et appareils de laboratoire, nommément soudeuses de tubes pour couper et souder de façon stérile des tubes de laboratoire en matière plastique. (2) Dispositifs médicaux, nommément soudeuses pour raccorder des tubes médicaux en matière plastique pour le traitement du sang et d'autres fluides biologiques; dispositifs médicaux, à savoir soudeuses de tubes pour couper et souder de façon stérile des tubes médicaux en matière plastique pour le traitement du sang et d'autres fluides biologiques.

Goods & Services

Laboratory equipment and apparatus, namely separating and welding devices in the nature of sealers for joining laboratory tubes of plastic material; Laboratory Equipment and apparatus, namely sterile tube sealers for cutting and welding of laboratory tubes of plastic material Medical devices, namely, separating and welding devices in the nature of sealers for joining medical tubes of plastic material for processing blood and other biological fluid; Medical devices, namely sterile tube sealers for cutting and welding medical tubes of plastic material for processing blood and other biological fluids

Abstract

Bag system (1) for collecting blood from an animal, comprising a collection bag (2) fluidly connected, by means of a first tubing (4) associated with an inlet port of the collection bag (2), to a first sampling needle (3), a second sampling needle (4) being connected by means of a second tubing (6), the second sampling needle (5) having an outer diameter that is different from the first sampling needle (3).

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus

Abstract

The invention relates to a composition for preserving platelets, comprising an additive solution containing (a) sodium chloride and (b) an acetate compound or a citrate compound or a combination thereof, and a red blood cell aggregation agent chosen from dextran having a molecular weight of 50 kDa or more, polyvinylpyrrolidone having a molecular weight of 40 kDa or more and polyethylene glycol having a molecular weight of 20 kDa or more, or a combination thereof.

IPC Classes  ?

• A01N 1/02 - Preservation of living parts
• A61K 35/19 - PlateletsMegacaryocytes
• C12N 5/078 - Cells from blood or from the immune system

Abstract

Disclosed is a device (23) for collecting a target volume of blood in a collecting bag connected to a collection needle via a flexible tube, comprising a plate (26) for the collecting bag, a clamping device (1) for clamping the flexible tube comprising (a) a bearing element having a bearing surface, (b) a clamping element having a clamping surface, the clamping element being able to move between an open position in which the flexible tube positioned between the bearing and clamping surfaces is not deformed and a closed position in which the flexible tube positioned between the bearing and clamping surfaces is closed off, and (c) a control unit configured to determine the volume of blood collected, and move the clamping element from the open position to an intermediate position, when the determined volume of blood collected reaches a predetermined volume.

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus
• A61B 5/15 - Devices for taking samples of blood
• A61B 5/157 - Devices for taking samples of blood characterised by integrated means for measuring characteristics of blood

Abstract

The invention relates to a clamping device (1) for clamping a flexible tube (2), comprising: - a bearing element (3) comprising a bearing surface (4), - a clamping element (5) comprising a clamping surface (6), said clamping element (5) being able to move between at least an obturation position in which a flexible tube placed between the bearing surface (4) and the clamping surface (6) is obstructed, and a closed position in which the bearing surface (4) and the clamping surface (5) are in contact, and - a control unit configured to: - actuate the clamping element (5) from the open position towards the closed position until it is blocked, - detect the position of the blocked clamping element (5), - determine the presence or absence of a flexible tube (2) according to the position of the clamping element (5) that has thus been detected.

IPC Classes  ?

• A61M 39/28 - Clamping means for squeezing flexible tubes, e.g. roller clamps

Abstract

The invention relates to a method for grafting a fibrous element for eliminating antibodies from blood or a blood component, said fibrous element having carboxylic acid functions, said method involving impregnating a fibrous element having carboxylic acid functions with a grafting solution comprising at least one oligosaccharide derivative that can bind to at least one antibody, said oligosaccharide derivative having at least one amine function, such as to ensure covalent bridging by formation of an amide bond between the oligosaccharide derivative and said fibrous element, the grafting solution comprising said oligosaccharide derivative solubilised in an organic solvent.

IPC Classes  ?

• B01J 20/32 - Impregnating or coating
• B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties

Goods & Services

Laboratory equipment and apparatus, Such as separating and welding devices for connecting tubes of plastic; Equipment and apparatus for the sterile joining of tubes of plastic. Medical device, Such as separating and welding devices for connecting tubes of plastic; Medical devices for the sterile joining of tubes of plastic.

Abstract

The invention relates to a method for preparing an irradiated platelet lysate, comprising the following steps: provision of a platelet lysate in order to obtain a starting platelet lysate, said starting platelet lysate comprising (i) platelet factors including growth factors and (ii) plasma proteins including coagulation factors and proteins other than the coagulation factors; and irradiation of the starting platelet lysate using UVC radiation with a wavelength of between 200 and 280 nm, in order to obtain a platelet lysate irradiated with UVC radiation, said irradiation being arranged to retain at least 75% of the total protein concentration of the starting platelet lysate, while reducing, by at least 20%, the concentration of at least one of the coagulation factors including fibrinogen, factor II, factor VII, factor IX, factor X and factor XI of the starting platelet lysate.

IPC Classes  ?

• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• C12N 5/078 - Cells from blood or from the immune system

Abstract

The invention relates to a method for preparing an irradiated platelet lysate, comprising the following steps: provision of a starting platelet lysate comprising (i) platelet factors including growth factors and (ii) plasma proteins including coagulation factors and proteins other than the coagulation factors; and double irradiation of the starting platelet lysate, using UVC radiation and ionizing radiation, said double irradiation with UVC radiation and ionizing radiation being arranged to retain at least 75% of the total protein concentration of the starting platelet lysate, while reducing, by at least 40%, the concentration of at least one of the coagulation factors including fibrinogen, factor II, factor VII, factor IX, factor X and factor XI of the starting platelet lysate.

IPC Classes  ?

• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• C12N 5/078 - Cells from blood or from the immune system

Abstract

The invention relates to an infusion system (1) comprising a bladder (2) comprising a first compartment (3) with a first solution and a second compartment (4) with a second solution, the first compartment (3) being provided with an inlet tube (5) and an outlet tube (6), and a connecting device (8) fluidly connecting the first compartment (3) and the second compartment (4), a reversible flow shutter (9) being interposed in the connecting device (8), said shutter being adapted, based on the differential pressure between the upstream and downstream of said shutter, to prevent or allow the flow of the second solution, the inlet tube (5) of the first compartment (3) opening into the first compartment (3) at a level higher than that at which the outlet tube (6) of the first compartment (3) opens.

IPC Classes  ?

• A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
• A61J 1/10 - Bag-type containers
• A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe
• A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor

Abstract

The invention concerns a protective case (18) for components of a bag system intended for treating a biological fluid, said bag system consisting of at least one filtration unit (2) for filtering the biological fluid, said protective case (18) comprising a cavity having a first space intended to receive said filtration unit (2) and at least one second space, said cavity being formed between a base element (19) and an element forming a lid (20) positioned removably on said base element (19), holding means for holding the filtration unit in said first space being arranged in said cavity, said holding means and the element forming a lid (20) operating in combination to prevent any movement of the filtration unit (2) inside the protective case (18), when said filtration unit (2) is arranged inside said holding means.

IPC Classes  ?

• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• A61M 1/02 - Blood transfusion apparatus
• B04B 5/04 - Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers

Abstract

The invention relates to a filtration unit (1) for filtering a fluid, comprising a rigid housing consisting of a first and a second housing member (2, 3) between which a filtration medium (4) is disposed, said housing having an inlet and an outlet conduit, each of said housing members comprising at least one dome-shaped portion (13, 14) delimited by a perimeter and having an inner wall (15, 16) extending from said perimeter to an apex (17, 18), and an outer wall (19,20) extending from the apex (17, 18) to the perimeter, wherein at least one of the inlet and outlet conduits opens out through the outer wall (19, 20), the inner wall (15, 16) and the outer wall (19, 20) respectively extend in a median plane forming therebetween an angle strictly greater than 90°, and the apex (17,18) has an outer curved profile extending between the median planes at the junction between the inner wall (15, 16) and the outer wall (17, 18).

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation

Abstract

The invention relates to a filtration unit (1) for filtering a fluid, comprising a housing consisting of a first housing element (2) and a second housing element (3) between which a filtration medium (4) is arranged in such a way as to define an inflow compartment (5) for the fluid to be filtered and an outflow compartment (6) for the filtered fluid, said housing comprising an inflow conduit (7) flowing into the inflow compartment (5) and an outflow conduit (8) flowing into the outflow compartment (6), each of said housing elements comprising a bottom (9, 10) extending in a median plane (P5, P6) while being surrounded by a periphery. Said housing elements (2, 3) are interconnected tightly around the periphery thereof, and the housing has a peripheral edge (27) with a curved outer profile that extends between the median planes (P5 P6) of the bottoms.

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation

Goods & Services

Non-medical apparatus and instruments for the automatic preparation of blood components for non-medical purposes, namely, blood separators for separating whole blood into components such as plasma, platelets and red blood cells; component parts for the aforementioned, sold as a unit, namely, filter holders, barcode readers, mixers, automatic cannula breakers, splash guards Medical apparatus and instruments for the automatic preparation of blood components for medical purposes, namely, blood separators for separating whole blood into blood components such as plasma, platelets and red blood cells; all the aforesaid apparatus being for the supply of products used for medical, therapeutic and diagnostic purposes

Goods & Services

Apparatus and instruments for automatic preparation of blood components. Medical apparatus and instruments for automatic preparation of blood components.

Goods & Services

Laboratory instruments, namely radiation devices for the treatment of body fluids. Medical devices, namely radiation devices for the treatment of body fluids.

Goods & Services

Pharmaceutical products, namely products, substances and solutions for the collection, preservation, storage, treatment, freezing, nutrition, cultivation, thawing, washing or transplanting of organs and tissues. Medical devices, namely flexible plastic bags and rigid plastic bottles for the collection, preservation, storage, treatment, freezing, nutrition, cultivation, thawing, washing or transplanting of organs and tissues.

Abstract

The invention relates to a filtration unit (1) for filtering a fluid, including a rigid housing formed of a first housing element (2) and a second housing element (3) between which is arranged a filtration medium (4), said filtration medium having a maximum thickness (Em) in said housing, the first housing element (2) and the second housing element (3) including first and second inner projections (14, 15), respectively, which extend in the housing, said inner projections (14, 15) being arranged to compress the filtration medium along the periphery thereof to an inner thickness (Ei) that is smaller than the maximum thickness (Em), the first and second housing elements (2, 3) further including first and second outer projections (16, 17), respectively, which extend in the housing, said outer projections being arranged to compress the filtration medium (4) to an outer thickness (Ee) of between 80% and 110% of the inner thickness (Ei).

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus
• A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation

Goods & Services

Supplements for cell culture media, for scientific purposes, with the exclusion of diagnostic purposes; Blood-based preparations rich in growth factors, for scientific purposes, with the exclusion of diagnostic purposes. Supplements for cell culture media, for medical and clinical purposes, with the exclusion of diagnostic purposes; Blood-based preparations rich in growth factors, for medical and clinical purposes, with the exclusion of diagnostic purposes. Medical devices containing supplements for cell culture media, other than for diagnostic purposes; Medical devices containing blood-based preparations rich in growth factors, other than for diagnostic purposes.

Abstract

A method for sterilising a platelet lysate in the liquid state comprising at least the endogenous growth factors TGF beta 1, EGF, PDGF-AB, IGF-1, VEGF and bFGF, said method comprising freezing said liquid platelet lysate in order to obtain a frozen platelet lysate and irradiating said frozen platelet lysate with ionising radiation in order to obtain a sterilised platelet lysate, said irradiation being adapted so as to preserve at least 80% of the concentration of at least one of the endogenous growth factors chosen from the group consisting of TGF beta 1, EGF, PDGF-AB, IGF-1 and VEGF.

IPC Classes  ?

• A61L 2/02 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor using physical phenomena
• A61L 2/08 - Radiation
• C07K 14/475 - Growth factorsGrowth regulators
• C12N 5/078 - Cells from blood or from the immune system

Abstract

A method for sterilising a platelet lysate in the liquid state comprising at least the endogenous growth factors TGF beta 1, EGF, PDGF-AB, IGF-1, VEGF and bFGF, said method comprising freezing said liquid platelet lysate in order to obtain a frozen platelet lysate and irradiating said frozen platelet lysate with ionising radiation in order to obtain a sterilised platelet lysate, said irradiation being adapted so as to preserve at least 80% of the concentration of at least one of the endogenous growth factors chosen from the group consisting of TGF beta 1, EGF, PDGF-AB, IGF-1 and VEGF.

IPC Classes  ?

• C12N 5/078 - Cells from blood or from the immune system
• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor

Abstract

The invention describes a method for separating blood constituents and analyzing the blood constituents (1, 10), comprising the method steps of pumping blood constituents (11, 101) from a first container (23) into a second container (24), the blood constituents in the first container (23) being separated into a light phase and a heavy phase, with one of the two phases being pumped from the first container (23) into the second container (24) and with the first container (23) being connected to the second container (24) by way of a connection piece (29), recording measurement values for determining the amount of the phase (12, 102) pumped from the first container (23) into the second container (24) and recording optical measurement values for determining the hemoglobin and/or lipid content of the phase (13, 103) pumped from the first container (23) into the second container (24), the recording of the optical measurement values for determining the hemoglobin and/or lipid content being carried out during the pumping process.

IPC Classes  ?

• G01N 33/49 - Physical analysis of biological material of liquid biological material blood
• A61M 1/02 - Blood transfusion apparatus
• G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated

Goods & Services

Supplements of cell culture media for scientific purposes, excluding use for diagnostic purposes; products derived from blood rich in growth factors, for scientific purposes, excluding use for diagnostic purposes. Supplements of cell culture media for medical and clinical use, excluding use for diagnostic purposes; products derived from blood rich in growth factors, for medical and clinical use, excluding use for diagnostic purposes. Medical devices containing supplements of cell culture media, excluding use for diagnostic purposes; medical devices containing products derived from blood rich in growth factors, excluding use for diagnostic purposes.

Abstract

The invention relates to a matrix in ball form comprising cross-linked fibrinogen, the matrix being free from fibrin, as well as to a method for preparing such a matrix, comprising the following steps: (a) providing an initial composition comprising fibrinogen and a platelet factor, (b) injecting said initial composition into an oil heated to a temperature of 50 °C to 80 °C so as to form an emulsion, (c) mixing the emulsion thus obtained at a temperature of 50 °C to 80 °C until a matrix in ball form is obtained, and (d) isolating the matrix thus obtained. The matrix is used as a cell carrier.

IPC Classes  ?

• C12M 1/12 - Apparatus for enzymology or microbiology with sterilisation, filtration, or dialysis means
• A61L 27/56 - Porous or cellular materials
• C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor

Goods & Services

(1) Compléments de milieux de culture de cellules, nommément, lysat de plaquettes sanguines, à usage scientifique, à l'exclusion de l'usage à des fins de diagnostic; Produits dérivés du sang riches en facteurs de croissance, nommément, lysat de plaquettes sanguines, à usage scientifique, à l'exclusion de l'usage à des fins de diagnostic. (2) Compléments de milieux de culture de cellules, nommément, lysat de plaquettes sanguines, à usage médical et clinique, à l'exclusion de l'usage à des fins de diagnostic; Produits dérivés du sang riches en facteurs de croissance, nommément, lysat de plaquettes sanguines, à usage médical et clinique, à l'exclusion de l'usage à des fins de diagnostic; Dispositifs médicaux, nommément, poches et flacons, contenant des compléments de milieux de culture de cellules, nommément, lysat de plaquettes sanguines, à l'exclusion de l'usage à des fins de diagnostic; Dispositifs médicaux, nommément, poches et flacons, contenant des produits dérivés du sang riches en facteurs de croissance, nommément, lysat de plaquettes sanguines, à l'exclusion de l'usage à des fins de diagnostic.

Abstract

The invention relates to a process for using a cell culture system in order to carry out a sequence of operations on said cells, said culture system comprising an assortment of sterile devices, said assortment of sterile devices comprising: - a culture device (1) comprising a culture container (4) suitable for culturing cells, - more than one transfer device (2) intended to enable the movement of fluid towards the culture device (1) or from said culture device (1), said transfer device (2) comprising at least one empty pouch (14) in fluidic communication with a primary transfer tubing (15) connected to which is one or more secondary transfer tubings (16), and - a multiple coupling device (3) in order to couple the culture device (1) to more than one transfer device (2), said multiple coupling device (3) comprising a plurality of coupling tubings (7), said process comprising the steps consisting in: (a) sterilely connecting one of the coupling tubings (7) of the multiple coupling device (3) to one of the transfer tubings (16) of the transfer device (2), (b) carrying out, in a closed system, an operation on the cells to be cultured, (c) once the operation has been carried out, disconnecting said transfer device (2) from said multiple coupling device (3), and (d) repeating the steps (a) to (c) with another transfer device (2) in order to carry out another operation on the cells.

IPC Classes  ?

• C12M 1/00 - Apparatus for enzymology or microbiology
• C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus

Abstract

The invention concerns a filtering unit (1) intended to allow the leukoreduction of the blood or of a blood component, comprising an outer shell (2) provided with at least one inlet opening (3) and at least one outlet opening (4), the shell enclosing a porous element interposed between said openings, said porous element enclosing at least one prefilter (7) for eliminating the aggregates and at least one leukoreduction medium (8) for leukoreduction by adsorption and/or by filtration of the leukocytes, the prefilter (7) for eliminating the aggregates comprising at least one coherent non-woven web comprising a mixture of first discontinuous thermoplastic fibres and second discontinuous thermoplastic fibres of which the melting point is lower than that of said first fibres, said first and second fibres being linked to each other by thermal junctions.

IPC Classes  ?

• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• B01D 39/16 - Other self-supporting filtering material of organic material, e.g. synthetic fibres
• A61M 1/02 - Blood transfusion apparatus

Goods & Services

Supplements for cell culture media, for scientific purposes, with the exclusion of diagnostic purposes; Blood-based preparations rich in growth factors, for scientific purposes, with the exclusion of diagnostic purposes. Supplements for cell culture media, for medical and clinical purposes, with the exclusion of diagnostic purposes; Blood-based preparations rich in growth factors, for medical and clinical purposes, with the exclusion of diagnostic purposes. Medical devices containing supplements for cell culture media, not for diagnostic purposes; Medical devices containing blood-based preparations rich in growth factors, not for diagnostic purposes.

Goods & Services

Pharmaceutical preparations for use for extracorporeal photophoresis, immunotherapy using cells modified by photochemistry, extracorporeal photochemotherapy.

Goods & Services

Pharmaceutical preparations for use for extracorporeal photophoresis, immunotherapy using cells modified by photochemistry, extracorporeal photochemotherapy.

Abstract

The invention relates to a method for extracting at least one first and one second blood component contained in a primary bag (2) of a bag system (1) which also includes at least one satellite bag (3) for collecting the first blood component in fluid communication with the primary bag (2), and a satellite bag (4) for collecting the second blood component arranged on the flow path defined between the primary bag (2) and the satellite bag (3), said method including the steps of: restricting the satellite bag (4) to a first volume; compressing the first bag (2) such as to extract the first blood component and transfer same at least partially into the satellite bag (3) passing by the satellite bag (4) restricted to the first volume; after extracting the first blood component, restricting the satellite bag (4) to a second volume; continuing to compress the primary bag (2) such as to extract the second blood component and transfer same at least partially into the satellite bag (4) restricted to the second volume.

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus

Goods & Services

Laboratory apparatus for blood treatment; laboratory apparatus for blood sampling; automatic laboratory stirrers for blood sampling. Medical devices for blood treatment; blood sampling devices.

Abstract

The invention concerns a connector (3) for an infusion bag (1) comprising at least first and second tubular bodies (4, 5) each forming an access opening and a base (6) extending around said first and second tubular bodies (4, 5), said base (6) being formed from a plate (7) comprising a welding area (8) intended to be welded to the walls of an infusion bag, the plate (7) further comprising a gripping area (9) that extends outside said welding area (8) between the first and second tubular bodies (4, 5), said gripping area (9) having a sufficient size and rigidity to allow gripping.

IPC Classes  ?

• A61J 1/10 - Bag-type containers
• A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor

Abstract

The invention relates to a connector (3) for an infusion bag comprising at least a first tubular body (4) forming an access opening, said tubular body (4) being provided with a bushing (14) having a perforable transverse wall (15) for ensuring the tight closure of the access opening, a perforable stopper (16) arranged hermetically on said transverse wall (15), and a cap (17) for compressing said perforable stopper (16) mounted on said bushing (14) onto the tubular body (4), the surface of said transverse wall (15) which is in contact with the stopper (16) being curved so as to locally increase the compression of said perforable stopper (16) between said cap (17) and said tubular body (4).

IPC Classes  ?

• A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
• A61J 1/10 - Bag-type containers
• A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe

Goods & Services

Automatic laboratory stirrers for blood sampling Medical devices for blood treatment, namely, blood mixers for medical purposes; blood sampling devices, namely, apparatus for mixing blood

Abstract

The invention pertains to an infusion system (1) comprising a set of pouches comprising at least one first pouch (2) and a second pouch (3), said first pouch (2) containing or intended to contain a first solution, said first pouch (2) having at least one first intake tube (4) forming an intake orifice and a second output tube (5) forming an output orifice, said first and second tubes each being arranged in an edge gasket (6) of said pouch, and said second pouch (3) containing or intended to contain a second solution; a connection device (10) placing or intended to place in fluid communication the first pouch (2) with its intake tube (4) and the second pouch (3); said edge gasket (6) comprising an extension (13) protruding towards the interior of said first pouch (2) so as to redirect the flow of the second solution coming from the second pouch (3) from the direct flow path between the intake tube (4) and output tube (5).

IPC Classes  ?

• A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
• A61J 1/10 - Bag-type containers
• A61M 5/315 - PistonsPiston-rodsGuiding, blocking or restricting the movement of the rodAppliances on the rod for facilitating dosing

Goods & Services

Laboratory apparatus for treating blood; Laboratory apparatus for sampling blood; Automatic laboratory agitators for sampling blood. Medical devices for treating blood; Blood collection devices.

Abstract

The invention concerns a method for preserving placental whole blood for the short term, in particular just after removal. The method comprises the steps of: introducing the placental whole blood into an air barrier storage bag, and storing said bag containing the placental blood at a temperature higher than 0°C and lower than 40°C. Moreover, the invention concerns a system of bags for implementing said method. The system comprises a collecting bag (1) in fluid communication, via a first tube (2) combined with an inlet opening of the collecting bag, with at least one extraction needle (3), and an air barrier storage bag (4), said bag being in fluid communication with the collecting bag.

IPC Classes  ?

• A01N 1/02 - Preservation of living parts
• A61J 1/10 - Bag-type containers

Abstract

The invention relates to an apparatus (9) for extracting at least one blood component contained in a primary bag (1) of a system of bags, said system of bags further including at least one bag (4) of solution containing an additive solution for said blood component, and at least one satellite bag (3) for collecting said blood compound with said additive solution added thereto, said bags (1, 3, 4) being connected to one another by tubes, said apparatus including: an extraction device (14) for extracting the blood compound by compressing the primary bag (1), a monitoring device (15) for enabling said extracted compound or said combination of the extracted compound and the additive solution to be transferred to the collecting satellite bag (3) via the tubes, an agitation device (16) for agitating the collecting satellite bag (3), and a drive system for controlling said extraction device (14), said monitoring device (15) and the agitation device (16), said system being designed so as to enable the uniform mixing of the extracted blood compound and the additive solution.

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus

Abstract

The invention relates to an apparatus (9) for extracting at least one blood component contained in a primary bag (1) of a system of bags, said system of bags further including at least one bag (4) of solution containing an additive solution for said blood component, and at least one satellite bag (3) for collecting said blood compound with said additive solution added thereto, said bags (1, 3, 4) being connected to one another by tubes, said apparatus including: an extraction device (14) for extracting the blood compound by compressing the primary bag (1), a monitoring device (15) for enabling said extracted compound or said combination of the extracted compound and the additive solution to be transferred to the collecting satellite bag (3) via the tubes, an agitation device (16) for agitating the collecting satellite bag (3), and a drive system for controlling said extraction device (14), said monitoring device (15) and the agitation device (16), said system being designed so as to enable the uniform mixing of the extracted blood compound and the additive solution.

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus

Abstract

The present invention relates to a centrifuge pod (11) which comprises a body (12) intended to accept products for treatment and a pivot-mounted lid (15) for sealing the contents of the pod. A rotary catch (19) mounted on the lid locks the lid to the body of said pod. A return element (32) such as a spring mounted in the hinge keeps said lid open at an oblique angle when the catch is not locked. In this way, an operator will immediately notice that a lid is not locked. In addition, if he attempts to close the lid of the centrifuge, the lid of the open pod will strike the lid of the centrifuge, preventing it from closing. The lid hinge is designed so that an operator has to open the lid to 180° in order to be able to remove it.

IPC Classes  ?

• B04B 5/04 - Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
• B04B 7/06 - Safety devices

Abstract

The invention relates to a centrifuge comprising a vertical shaft (11) rotated by a motor and a balancing mechanism (32) for balancing the parts secured to said vertical shaft (11), said mechanism comprising: a plate (10, 14) secured to the vertical shaft; at least one compensating mass (13, 15) moving freely on the plate (10, 14), said mass being designed to limit the imbalance of the parts secured to the vertical shaft (11); and a mechanism for blocking the compensating mass, said blocking mechanism being designed to immobilise the compensating mass (13, 15) on the plate when the rotational speed exceeds a pre-determined value.

IPC Classes  ?

• B04B 9/10 - Control of the driveSpeed regulating
• B04B 9/14 - Balancing rotary bowls
• F16F 15/36 - Correcting- or balancing-weights or equivalent means for balancing rotating bodies, e.g. vehicle wheels operating automatically

Abstract

The invention relates to a method for controlling the rotational speed of a vertical shaft (11) of a centrifuge. A control module controls the rotational speed of the shaft and receives, from a sensor (37), signals relating to the level of vibrations measured inside the centrifuge. First, the rotation of the shaft is accelerated until a first pre-determined speed NI lower than a speed set value is reached, then it is decelerated until a second pre-determined speed N2 is reached. The control module determines the maximum vibration level during the acceleration and deceleration. If the vibration level has not exceeded a certain threshold, the centrifuge cycle for reaching the speed set value is launched. In order to improve said method, at least one compensating mass (13, 15) is positioned during the acceleration in order to limit the imbalance of the parts secured to the shaft (11). The invention also relates to the associated centrifuge and control program.

IPC Classes  ?

• B04B 9/10 - Control of the driveSpeed regulating
• B04B 9/14 - Balancing rotary bowls

Abstract

The invention relates to a container (1) including an outer shell having two flexible walls (2) combined together so as to from at least one main compartment (3) containing or intended to contain a fluid, said container (1) further including at least one flow pipe (4), one end of which leads into said main compartment (3), and the other end of which extends beyond said flexible walls (2), said flow pipe (4) being combined with said flexible walls (2) along a proximal joint (6) and a distal joint (7) that is separate from the proximal joint (6), said flexible walls (2) surrounding the portion of the flow pipe (4) between said joints (6, 7) so as to form a closed, inaccessible sealing chamber (8) around said flow pipe portion (4).

IPC Classes  ?

• A61J 1/10 - Bag-type containers
• A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
• B29C 65/18 - Joining of preformed partsApparatus therefor by heating, with or without pressure using heated tool
• B65D 75/30 - Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
• A61J 1/18 - Arrangements for indicating condition of container contents, e.g. sterile condition

Abstract

The invention relates to the use of a material capable of binding itself to the prion protein in order to remove, in an organic material, the etiologic agent inducing a novel neurodegenerative disease other than Creutzfeldt Jakob diseases.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61M 1/02 - Blood transfusion apparatus

Abstract

The invention relates to a kit for preserving a biological product including a three-dimensional bag (1) intended for holding said biological product, said bag (1) having a substantially constant three-dimensional geometry during the use thereof, as well as a casing (2) intended for packing said bag, said casing (2) including a cavity (3) arranged such as to receive said bag (1), said cavity (3) having a substantially constant three-dimensional geometry during the use thereof, and a slot (4) being provided along one edge of said cavity such as to enable said bag (1) to be inserted in said cavity (3), a front strip (5) and a rear strip (6) extending on the outside away from said slot (4), said strips being intended for being combined with one another in order to provide an airtight seal of said cavity (3) of the casing (2).

IPC Classes  ?

• A61J 1/10 - Bag-type containers
• A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor

Abstract

The invention relates to a kit for preserving a biological product including a three-dimensional bag (1) intended for holding said biological product, said bag (1) having a substantially constant three-dimensional geometry during the use thereof, as well as a casing (2) intended for packing said bag, said casing (2) including a cavity (3) arranged such as to receive said bag (1), said cavity (3) having a substantially constant three-dimensional geometry during the use thereof, and a slot (4) being provided along one edge of said cavity such as to enable said bag (1) to be inserted in said cavity (3), a front strip (5) and a rear strip (6) extending on the outside away from said slot (4), said strips being intended for being combined with one another in order to provide an airtight seal of said cavity (3) of the casing (2).

IPC Classes  ?

• A01N 1/02 - Preservation of living parts
• A61J 1/16 - Holders for containers
• A61J 1/10 - Bag-type containers
• A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor

Goods & Services

PHARMACEUTICAL PRODUCTS, NAMELY, SOLUTIONS FOR USE IN CONNECTION WITH THE PROCESSING OF BLOOD AND BLOOD COMPONENTS FOR MEDICAL PURPOSES, BAGS FILLED WITH SOLUTIONS FOR PROCESSING BLOOD FOR MEDICAL PURPOSES; NONE OF THE FOREGOING BEING PREPARATIONS OF THE TREATMENT OF COLDS OR INFLUENZA MEDICAL DEVICES FOR PROCESSING BLOOD, NAMELY, MEDICAL KITS COMPRISED OF BLOOD FILTERS, POUCHES AND PLASTIC TUBING; POUCH AND CONTAINER SYSTEMS COMPRISING BLOOD COLLECTION BAGS FOR MEDICAL PURPOSES FOR THE PROCESSING OF BLOOD OR BLOOD COMPONENTS

Abstract

The invention relates to a device intended to break at least one closure element (20) located inside a flexible tube (21), said closure element (20) having a first part (22) and a second part (23), said parts being separated by a weakening zone (24), it being possible to break said weakening zone (24) in order to enable fluid to flow inside said flexible tube (21), said device comprising an assembly (26) for holding said flexible tube (21), said assembly (26) comprising a fixed element (27) provided with a first housing (28) intended to hold a first portion of said flexible tube, and a mobile element (29) provided with a second housing (30) intended to hold a second portion of said flexible tube, the two housings (28, 30) being aligned along a centre line (31) defining a neutral position of the mobile element (29), said device comprising a member (36) for moving the mobile element (29) to either side of its neutral position so as to be able to break the weakening zone (24) of the closure element (20).

IPC Classes  ?

• A61M 39/22 - Valves or arrangement of valves

Abstract

The invention relates to a device intended to break at least one closure element (20) located inside a flexible tube (21), said closure element (20) having a first part (22) and a second part (23), said parts being separated by a weakening zone (24), it being possible to break said weakening zone (24) in order to enable fluid to flow inside said flexible tube (21), said device comprising an assembly (26) for holding said flexible tube (21), said assembly (26) comprising a fixed element (27) provided with a first housing (28) intended to hold a first portion of said flexible tube, and a mobile element (29) provided with a second housing (30) intended to hold a second portion of said flexible tube, the two housings (28, 30) being aligned along a centre line (31) defining a neutral position of the mobile element (29), said device comprising a member (36) for moving the mobile element (29) to either side of its neutral position so as to be able to break the weakening zone (24) of the closure element (20).

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus
• A61M 39/22 - Valves or arrangement of valves

Goods & Services

Medical devices, namely pouches designed to contain a solution for a drip.

Goods & Services

Protective respiratory masks for industrial purposes, including single-use masks; Masks incorporating valves; Half-face filter masks for industrial purposes, for respiratory protection; Filters for protective respiratory masks for industrial purposes. Protective respiratory masks for medical purposes, surgical masks, protective masks for use by medical personnel.

Abstract

The invention relates to a method for expanding and/or preserving cells inside a culture vessel (1) containing a culture medium, said method providing for the renewal of said culture medium by means of a culture medium stream, at least a portion of which comes from a culture medium volume contained in a gas-enrichment vessel (7) of said culture medium, said enrichment vessel (7) further containing a gas volume which is separated from the culture medium volume by a free interface, said gas volume being renewed by means of a gas stream which is introduced into the enrichment vessel (7) directly into the gas volume, the flow of said stream being arranged so as to enable a gas exchange between said culture medium volume and said gas volume at the interface thereof.

IPC Classes  ?

• C12M 1/04 - Apparatus for enzymology or microbiology with gas introduction means
• C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
• C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor

Goods & Services

Protective respiratory masks for industrial purposes; RFID-based computer software for coding, identifying, monitoring and controlling data relating to blood, blood components and/or pharmaceutical preparations. Medical devices for the withdrawal, collection, storage, processing, analysis, sampling, filtering, separation and/or administration of blood, blood components, biological cells, organs and/or tissues; Transfusion devices for medical purposes; Perfusion devices for medical purposes; Sampling containers for medical use; Infusion and collection containers for medical use; Dropper devices for medical purposes (droppers, dropper bottles); Syringes and syringe needles for medical use; Containers and apparatus for administering enteral and parenteral solutions, for medical purposes; Catheters of all kinds; Connectors for tubes for medical use, fastenings for tubes for medical use; Injection sites for medical purposes; Needleless connectors, needleless ports, needleless injection sites for medical purposes, Medical valves; Pressure regulators, flow controllers, pressure sensors, blood sampling devices for medical purposes; Pumps for medical purposes, Medical infusion pumps; Drip devices for medical purposes; Drip bags, sample bags for medical purposes; Filters for blood or blood components for medical purposes; Apparatus for administering medical fluids, perfusion kits for medical purposes; Face masks for medical purposes; Protective respiratory masks for medical purposes; Lighting machines for reducing pathogens of the blood and transfusion devices for reducing pathogens of the blood (medical apparatus); Machines for separating blood into blood components (medical apparatus); Parts and fittings for all the aforesaid goods. Scientific and technological services and research and design relating thereto in the field of medicine, namely the field of blood processing, the field of blood preservation, blood component preservation, organ preservation, cell and tissue preservation, the field of protective respiratory masks, the field of injectable medicated and non-medicated solutions. Medical services for the collection, preservation, storage, treatment, nutrition, culture, freezing, thawing, washing, reinjection, transformation and transplantation of biological cells, organs and tissues.

Abstract

The invention relates to a stable, liquid, ready-to-use ketoprofen formulation for parenteral administration, including ketoprofen dissolved in a solely aqueous solvent to which a buffering agent has been added, said formulation being adjusted to a pH greater than 5.5 and less than 6.5.

IPC Classes  ?

• A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
• A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
• A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
• A61K 9/08 - Solutions

Goods & Services

Medical devices, namely pouches for holding biological preparations, in particular blood or blood components.

Abstract

The invention relates to a bag system (1) for receiving and collecting a sample of a biological fluid or of one of the components thereof, comprising: - at least one main bag (2) for receiving the biological fluid or one of the components thereof, said main bag (2) being provided with at least one inlet orifice (25) and with an outlet orifice (26) for the fluid, - at least one secondary bag (21) for receiving the biological fluid or one of the components thereof, said bag (21) being in fluid communication with the main bag (2) by way of at least one other tube (28) connected to an orifice (27) of the secondary bag (21) and to one (26) of said orifices of the main bag (2), and – at least one sampling container (3) in fluid communication with said main bag (2) by way of a tube (5) connected to a second outlet orifice (7) of the main bag (2), so as to be able to receive a sample of the fluid contained in said bag, said sampling container (3) being provided with an access orifice (4) to the sample, and comprising an opening device (9) mounted in said orifice (4) of the container, said opening device (9) having a zone of weakness (10) designed to be able to be broken so as to permit access to the sample by way of the orifice (4) of said container.

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus
• A61J 1/12 - Bag-type containers with means for holding samples of contents
• A61B 5/15 - Devices for taking samples of blood

Abstract

The invention relates to a method for modifying the physical, chemical and/or biological properties of a fluid by irradiation using a metered amount of radiation, said method including feeding a flow of fluid to be irradiated into an irradiation chamber and applying said metered amount of radiation onto the flow of fluid to be irradiated in a predetermined portion of the irradiation chamber, said flow being focused in said portion according to a shape arranged so that said metered amount modifies the properties of said fluid. The invention also relates to a system for implementing said method.

IPC Classes  ?

• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor

Goods & Services

Pharmaceutical preparations such as solutions for use in the processing of blood and blood components; solutions contained in pouches for the processing, by photochemical means or by illumination, of blood or blood components in order to reduce pathogens; except preparations for the treatment of colds or influenza. Medical devices for processing blood; pouch and container systems for the processing, by photochemical means or by illumination, of blood or blood components in order to reduce pathogens; parts and constituents of all the aforesaid devices.

Abstract

A filtration unit (1) for a biological fluid, comprising an external jacket formed from two flexible films (2, 3) between which the edge (4) of a filter medium (5) is connected along a peripheral seal (6) so as to form, on either side of said filter medium, an inlet compartment (7) and an outlet compartment (8), said filtration unit also comprising an inlet port (10) in communication with said inlet compartment and an outlet port (11) in communication with said outlet compartment, each of the films (2, 3) comprising at least one tongue (12, 13, 14, 15) which extends out from the peripheral seal (6), a port (10, 11) being connected between two tongues (12, 13, 14, 15) of in each case one film (2, 3), and the peripheral seal (6) having a discontinuity (16, 17) between one of said tongues (12, 15) and the filter medium (5) in order that the port (10, 11) and the compartment (7, 8) are in communication.

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus
• B01D 63/00 - Apparatus in general for separation processes using semi-permeable membranes
• B01D 63/08 - Flat membrane modules
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation

Abstract

Method for stimulating the proliferation of differentiated cells belonging to the chondrogenic lineage, comprising the step of culturing the differentiated cells in a culture medium comprising glycylglycine in an amount sufficient to stimulate the proliferation of said cells.

IPC Classes  ?

• C12N 5/077 - Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells

Goods & Services

Pharmaceutical and veterinary preparations; sanitary preparations for medical purposes; dietetic substances adapted for medical use; disinfectants; infusion solutions for medical use such as electrolyte solutions, saline, medicated, dextrose, Ringer's lactate, mannitol solutions; rinsing solutions for medical use; preparations for enteral and parenteral nutrition; fluid replacement and blood rehabilitation solutions for medical use; solutions for preservation of blood, blood components, organs and/or tissues for medical use. Respiratory protective masks for industrial purposes; software based on RFID technology for encoding, identifying, monitoring and controlling data concerning blood, blood components and/or pharmaceutical preparations. Medical devices for drawing, collection, storage, treatment, analysis, sample selection, filtration, separation and/or administration of blood, of blood composites, of biological cells, of organs and/or tissues; transfusion devices for medical use; infusion devices for medical use; sampling containers for medical use; infusion and collection containers for medical use; dropper devices for medical purposes (droppers, dropper bottles); syringes and syringe needles for medical purposes; containers and apparatus for administration of enteral and parenteral solutions for medical use; catheters of all types; tube connectors for medical use, tube fasteners for medical use; injection ports for medical use; needleless connectors, needleless ports, needleless injection ports for medical use, medical valves; pressure controllers, flow regulators, pressure sensors, blood sampling devices for medical use; pumps for medical purposes, infusion pumps for medical use; infusion devices for medical use; infusion bags, blood collection bags for medical use; filters for blood and blood components for medical use; apparatus for administration of medical liquids, infusion sets for medical use; facial masks medical use; respiratory protective masks for medical use; illumination machines for reducing blood pathogens, and transfusion devices for reducing blood pathogens (medical apparatus); machine for separating blood into blood components (medical apparatus); parts and component parts for all the above goods. Scientific and technological services and research and design relating thereto in the medical field, namely in the field of treating blood, the field of preserving blood, blood components, organs, cells and tissues, the field of respiratory protective masks, the field of medicated and non-medicated solutions for injection. Medical services for the collection, preservation, storage, treatment, nutrition, culture, freezing, thawing, washing, reinjection, transformation and transplantation of biological cells, organs and tissues.

Goods & Services

Pharmaceutical and veterinary preparations; sanitary preparations for medical purposes; dietetic substances adapted for medical use; disinfectants; perfusion solutions for medical purposes, including electrolyte, saline, medicated, dextrose, Ringer lactate solutions, mannitol solutions; rinsing solutions for medical purposes; preparations for enteral and parenteral feeding; solutions for temporary fluid replacement and for blood replacement, for medical purposes; solutions for preserving blood, blood components; preparations, substances and solutions or media for collecting, preserving, storing, treating, feeding, growing, freezing, thawing, washing, reinjecting, processing, transplanting biological cells, organs and tissues. Protective respiratory masks for industrial purposes; RFID-based computer software for coding, identifying, monitoring and controlling data relating to blood, blood components and/or pharmaceutical preparations. Medical devices for the withdrawal, collection, storage, processing, analysis, sampling, filtering, separation and/or administration of blood, blood components, biological cells, organs and/or tissues; transfusion devices for medical purposes; perfusion devices for medical purposes; sampling containers for medical use; infusion and collection containers for medical use; dropper devices for medical purposes (droppers, dropper bottles); syringes and syringe needles for medical use; containers and apparatus for administering enteral and parenteral solutions, for medical purposes; catheters of all kinds; connectors for tubes for medical use, fastenings for tubes for medical use; injection sites for medical purposes; connectors without needles, ports without needles, injection sites without needles for medical purposes, medical valves; pressure regulators, flow controllers, pressure sensors, blood sampling devices for medical purposes; pumps for medical purposes, perfusion pumps for medical purposes; drip devices for medical purposes; drip bags, sample bags for medical purposes; filters for blood or blood components for medical purposes; apparatus for administering medical fluids, perfusion kits for medical purposes; face masks for medical purposes; protective respiratory masks for medical purposes; lighting machines for reducing pathogens of the blood and transfusion devices for reducing pathogens of the blood (medical apparatus); machines for separating blood into blood components (medical apparatus); parts and fittings for all the aforesaid goods. Scientific and technological services and research and design relating thereto in the field of medicine, namely the field of blood processing, the field of blood preservation, blood component preservation, organ preservation, cell and tissue preservation, the field of protective respiratory masks, the field of injectable medicated and non-medicated solutions. Medical services for the collection, preservation, storage, treatment, nutrition, culture, freezing, thawing, washing, reinjection, transformation and transplantation of biological cells, organs and tissues.

Abstract

The invention relates to an irradiation apparatus for inactivating pathogens
and/or
leukocytes in a biological fluid such as a platelet suspension and/or plasma
comprising:
a casing, a support member for carrying at least one irradiation bag
containing the
biological fluid, a light source comprising two banks of light disposed above
and below
the support member, and an agitating system for moving the support member, the
light
source generating UVC light of suitable intensity to inactivate pathogens
and/or
leukocytes and the agitation system moving the support member in an orbital
path with
predetermined amplitude and rotational frequency suitable to expose the whole
biological fluid to UVC.

IPC Classes  ?

• A61L 2/10 - Ultraviolet radiation
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• C12N 7/04 - Inactivation or attenuationProducing viral sub-units

Abstract

The invention relates to an irradiation apparatus for inactivating pathogens and/or leukocytes in a biological fluid such as a platelet suspension and/or plasma comprising: a casing (2), a support member (3) for carrying at least one irradiation bag (19) containing the biological fluid, a light source (4) comprising two banks of light (5, 6) disposed above and below the support member (3), and an agitating system (25) for moving the support member (3), the light source generating UVC light of suitable intensity to inactivate pathogens and/or leukocytes and the agitation system moving the support member in an orbital path with predetermined amplitude and rotational frequency suitable to expose the whole biological fluid to UVC.

IPC Classes  ?

• A61L 2/10 - Ultraviolet radiation
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• C12N 7/04 - Inactivation or attenuationProducing viral sub-units

Abstract

The invention relates to a filtration unit intended to allow the selective elimination of target substances from a fluid such as blood or a blood component, comprising an outer envelope formed from two flexible sheets joined together over their periphery along a bond line so as to define an inner volume, the envelope containing a filtering medium which delimits, on both sides of said bond line, an inlet compartment of the fluid to be filtered and an outlet compartment of the filtrate, each of the compartments being provided with an element - respectively an inlet and outlet element - for bringing said compartment into communication with the outside, said elements being connected between the sheets and comprising a flow channel that passes through the bond line, said unit being characterized in that at least one channel is offset relative to the bond line towards the compartment with which said channel is in communication.

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• B29C 65/00 - Joining of preformed partsApparatus therefor

Abstract

The invention relates to a filtration unit intended to allow the selective elimination of target substances from a fluid such as blood or a blood component, comprising an outer envelope formed from two flexible sheets joined together over their periphery along a bond line so as to define an inner volume, the envelope containing a filtering medium which delimits, on both sides of said bond line, an inlet compartment of the fluid to be filtered and an outlet compartment of the filtrate, each of the compartments being provided with an element - respectively an inlet and outlet element - for bringing said compartment into communication with the outside, said elements being connected between the sheets and comprising a flow channel that passes through the bond line, said unit being characterized in that at least one channel is offset relative to the bond line towards the compartment with which said channel is in communication.

IPC Classes  ?

• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• B29C 65/00 - Joining of preformed partsApparatus therefor
• A61M 1/02 - Blood transfusion apparatus

Abstract

The present invention relates to a blood bag system, a method for its manufacture, and a process for reducing pathogens and leucocytes in biological fluids in particular in therapeutic quantities of platelet concentrates (PC) contained in the blood bag system, using UV-light and agitation, wherein part of the plasma of the PC is optionally exchanged against a platelet additive solution.

IPC Classes  ?

• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61M 1/02 - Blood transfusion apparatus
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• C12N 7/04 - Inactivation or attenuationProducing viral sub-units

Abstract

The present invention relates to a blood bag system, a method for its manufacture, and a process for reducing pathogens and leucocytes in biological fluids in particular in therapeutic quantities of platelet concentrates (PC) contained in the blood bag system, using UV-light and agitation, wherein part of the plasma of the PC is optionally exchanged against a platelet additive solution.

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus
• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61J 1/00 - Containers specially adapted for medical or pharmaceutical purposes
• C12N 7/04 - Inactivation or attenuationProducing viral sub-units
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation