THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (USA)
Inventor
Arazi, Itzhak
Grotewold, Erich
Kenea, Hawi Deressa
Castaneda Mendez, Oscar Fernando
Barg, Rivka
Abstract
A Solanaceous plant exhibiting a facultative parthenocarpy and at least 80 % of fruit yield being devoid of homeotic aberrations and comprising a loss-of-function mutation in &MBP22 gene is provided. Also provided are methods of producing and using same.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Gur, Amit
Paris, Harry Stuart
Tzuri, Galil
Abstract
A Cucurbita pepo subsp. pepo plant is provided. The Cucurbita pepo subsp. pepo plant comprises a genome having a loss of function mutation in a Cp4.1LG13g07780 gene or ortholog thereof, wherein the loss of function mutation confers a multiflowering (mf) trait. Also provided are methods of producing and using such plants.
A01H 6/34 - Cucurbitaceae, e.g. bitter melon, cucumber or watermelon
C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
3.
METHODS AND SYSTEMS FOR COLORIMETRIC DETECTION OF QUIESCENT COLLETOTRICHUM IN HARVESTED FRUIT
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Eltzov, Evgeni
Alkan, Noam
Abstract
The present invention is in the general area of post-harvest fruit disease detection, more pertinently the present invention is directed towards methods for colorimetric detection of pathogenic fungi in their latent phase in harvested fruit, using a paper/plate -based reverse transcription loop- mediated isothermal amplification (RT-LAMP). The present invention provides a paper-based device for performing reverse transcription loop-mediated isothermal amplification (RT-LAMP) with real-time simultaneous detection of C. gloeosporioides latent infections in tomatoes. RT- LAMP -based PAD platform comprises a paper substrate on which the RNA amplification reaction occurs. The assay provided by the present invention is highly specific for the latent stage of C. gloeosporioides with an analytical sensitivity of 0.5 pg of total extracted RNA, with results obtained within 40 min and hence can be efficiently employed for identifying C. gloeosporioides in resource-limited setting.
C12Q 1/6865 - Promoter-based amplification, e.g. nucleic acid sequence-based amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Schaffer, Arthur Aaron
Schaffer, Amos Avraham
Cohen, Shahar
Klutzky, Galina
Doron-Faigenboim, Adi
Eselson, Elena
Davidovich-Rikanati, Rachel
Abstract
Methods for modification of the cucurbitacin biosynthetic pathway by inhibition of cucurbitacin biosynthetic pathway enzymes in plants and plant cells, production of cucurbit plants and plant cells having modified cucurbitacin and cucurbitacin derivatives, plants and plant cells modified thereby and their propagation, and compositions comprising the modified plants and plant cells are provided.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Halachmi, Ilan
Godo, Assaf
Lepar, Joseph
Glasser, Tzach
Bar Shamai, Alon
Abstract
A system for monitoring livestock of small ruminants comprises: (a) a physically limited receptacle configured for singly accessible by the small ruminants; (b) a drinking trough configured for metering water consumed by an animal; (c) a weighbridge configured for weighing the animal; (d) an IR animal presence sensor; (e) an RFID identification reader; and (f) a control unit. The drinking trough is cooperatively arranged with the weighbridge such that the small ruminant during drinking from the drinking trough stand on the weighbridge. The IR animal presence sensor and RFID identification reader are disposed in proximity of the drinking trough. The control unit is configured for attributing water consumption readings measured by the water meter and live weight readings measured by the weighbridge of the small ruminant identified by the RFID identification reader within a time period of presence detected by the IR animal presence sensor.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Mechrez, Guy
Benhaim, Avital
Shpigelman, Ziv
Feldbaum, Reut
Abstract
The present invention is directed to hybrid casein nanoparticles comprising a polynucleotide bound thereto, methods of manufacturing thereof and use thereof such as for intracellular delivery of polynucleotides to a plant.
C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
7.
HYPERSPECTRAL IMAGING METHOD AND SYSTEM USING A FLOCK OF SENSORS
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
RAMOT AT TEL AVIV UNIVERSITY LTD. (Israel)
Inventor
Klapp, Iftach
Sochen, Nir
Reshef, Liad
Oz, Navot
Berman, Omri
Goldstein, Eitan
Mendlovic, David
Zilberberg, Liron
Abstract
A method and system for hyperspectral imaging uses a flock of at least two sensors which provide images of an overlapped region-of-interest in at least two different spectral bands. The latter may include a visual band and one or more infrared bands. Using a variety of calibration, registration, super-resolution, and data fusion algorithms, a signal processor corrects and analyzes the images to form a hyperspectral image cube with high spatial resolution. The signal processor typically is in communication with or integrated with a tracking station, and it may be spaceborne, airborne, shipborne, or gound-based. An exemplary neural network is provided for implementation of the method for hyperspectral imaging.
H04N 23/11 - Cameras or camera modules comprising electronic image sensorsControl thereof for generating image signals from different wavelengths for generating image signals from visible and infrared light wavelengths
8.
BIODEGRADABLE ULVAN ARTICLES, USES AND PREPARATION THEREOF
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
SHENKAR - ENGINEERING. DESIGN. ART (Israel)
ISRAEL OCEANOGRAPHIC AND LIMNOLOGICAL RESEARCH, LTD. (Israel)
Inventor
Solomon, Eitan
Lewitus, Dan
Klin, Gavriel
Abstract
There is provided an ulvan article (e.g. an ulvan-based film, an ulvan-based package, etc.) obtained by a hot melt processing, such as by extrusion, or hot press molding. The ulvan article is optionally characterized a water content between about 1 and about 25%. Furthermore, methods for manufacturing or shaping of ulvan-based articles from Ulva extracts via hot melt processing (e.g. extrusion, hot press molding, etc.) are also provided.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Eyal, Yoram
Goldenberg, Livnat
Carmi, Nir
Sherman, Amir
Ophir, Ron
Abstract
A citrus plant is provided. The plant comprises a genome having a loss of function mutation in a Cg2g000710 gene or ortholog thereof, wherein the citrus plant is a natural producer of coumarin or furanocoumarin (FC). Also provided are methods of producing such plants.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Poverenov, Elena
Itzhakov, Rafael
Abstract
The present application provides hydrogel comprising an amine-containing macromolecule and an oxidized nucleoside, compositions and kits comprising the same, method for preparing them and uses thereof.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61L 31/12 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material
A61L 31/16 - Biologically active materials, e.g. therapeutic substances
A61L 24/00 - Surgical adhesives or cementsAdhesives for colostomy devices
A61K 49/18 - Nuclear magnetic resonance [NMR] contrast preparationsMagnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
11.
ESTIMATION OF A CROP COEFFICIENT VECTOR BASED ON MULTISPECTRAL REMOTE SENSING
The state of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Org. (Israel)
Inventor
Rozenstein, Offer
Tanny, Josef
Kaplan, Grigorii
Abstract
A system and method for estimating a crop coefficient vector (CCV) uses one or more remote sensors that provide multispectral images of a crop growing area. The CCV includes a crop coefficient estimate, KC, and at least one of a leaf area index estimate, LAI, and a crop height estimate, CH. The system includes one or more remote sensing subsystems (RSS); a preprocessor configured to generate harmonized spectral data from multispectral images; a vegetation index (VI) processor to calculate VIs from the harmonized spectral data; a storage medium containing pre-determined regression coefficients; and a CCV processor configured to calculate an estimated CCV. The RSS includes an image sensor mounted on a platform which may be airborne, such as an unmanned aerial vehicle, or space-borne, such as an orbiting satellite. The image sensor includes visual and/or infrared bands.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Koltai, Hinanit
Mechrez, Guy
Shalev, Nurit
Benhaim, Avital
Abstract
Provided herein is a composition comprising a hydrogel covalently bound to a functional moiety, wherein the hydrogel comprises a cross linkable biopolymer and a first cell population; the cross linkable biopolymer is at least partially crosslinked by a crosslinking agent within the hydrogel; and the functional moiety has a binding affinity to a cell. Furthermore, a method of growing cells using the composition of the invention, and a method of manufacturing the composition using a kit disclosed herein are also provided.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Cinnamon, Yuval
Ben-Tal Cohen, Enbal
Abstract
The present disclosure relates to deoxyribonucleic acid (DNA) editing agents, and their use in preparing DNA-edited cells and birds. The present disclosure further relates to gene-edited or genetically modified avians and gene-edited or genetically modified avian primordial germ cells (PGCs) for producing gene-edited or genetically modified avians (birds) that can serve as surrogate hosts for donor PGCs. The present disclosure further relates to methods for producing avian strains that can produce viable embryos and offspring, in both sexes, and for their subsequent use as surrogate hosts for donor PGCs.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Mechrez, Guy
Mani, Karthik Ananth
Dombrovsky, Aviv
Abstract
A composition comprising an emulsion comprising a plurality of core-shell particles is provided. Furthermore, an insecticidal composition and use thereof so as to prevent or arrest growth of an insect or aphid is also provided. Further, a method for preventing or inhibiting growth of an insect or aphid on a plant or within the area under cultivation is provided.
A01N 25/24 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients to enhance the sticking of the active ingredients
15.
PICKERING EMULSION FOR COATING ENTOMOPATHOGENIC NEMATODES
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (USA)
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (USA)
Inventor
Ment, Dana
Mechrez, Guy
Karasik, Liliya
Ramakrishnan, Jayashree
Shapiro-Ilan, David I.
Wu, Shaohui
Abstract
Provided herein is a composition comprising a Pickering emulsion comprising a plurality of core-shell particles encapsulating an entomopathogenic organism. Furthermore, a method for controlling a pest on or within a plant or at the area under cultivation is provided.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Cinnamon, Yuval
Ben-Tal Cohen, Enbal
Abstract
The present disclosure relates to deoxyribonucleic acid (DNA) editing agents, and their use in preparing genetically modified cells and birds. The present disclosure further relates to fertile genetically modified avians and genetically modified avian primordial germ cells (PGCs) for producing sterile genetically modified avians (birds) that can serve as surrogate hosts for donor PGCs. The present disclosure further relates to methods for producing fertile avian strains that can produce a population of embryos and offspring, in both sexes, all of which are sterile and viable, and further relates to their subsequent use as sterile surrogate hosts for donor PGCs.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Shimshoni, Jakob
Paz Kagan, Tarin
Birenboim, Matan
Kengisbuch, David
Chen, Yaira
Sadeh, Alona
Maurer, Dalia
Chalupowicz, Daniel
Abstract
A method and respective system are described. The method provides classification of cannabis inflorescence, and comprising: grinding said cannabis inflorescence; and determining a spectrogram of ground cannabis inflorescence; and providing data indicative of said spectrogram to trained machine learning system, pretrained on classification of material composition of cannabis inflorescence, to thereby obtain output data indicative of at least one of composition of selected cannabinoids and terpenes in said cannabis inflorescence, and varieties of said cannabis inflorescence.
G01N 21/25 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 21/359 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
G01N 21/62 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
B07C 5/342 - Sorting according to other particular properties according to optical properties, e.g. colour
G01N 21/84 - Systems specially adapted for particular applications
18.
PARTICLES COMPRISING DOUBLE STRANDED RNA AND USE OF SAME IN AGRICULTURE
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Fluhr, Robert
Alkan, Noam
Abstract
The present invention is directed to an anti-fungal composition including a plurality of particles including: at least one dsRNA molecule including a nucleic acid sequence complementary to at least one transcript of at least one essential gene of a fungus, and methods of using same.
A01N 25/22 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients stabilising the active ingredients
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Biran, Jakob
Cnaani, Avner
Segev, Adi
Slosman, Tatiana
Abstract
A fish of a tilapia genus comprising a loss-of-function mutation in a slc45a2 gene, wherein the mutation is in a homozygous form, and wherein the loss-of-function mutation results in an albino-red phenotype of the fish is disclosed. Methods of generating the fish are also disclosed.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
BAR-ILAN UNIVERSITY (Israel)
Inventor
Mechrez, Guy
Mani, Karthik Ananth
Cohen, Raz
Pirmatova, Madina
Bareket, Yifat
Banin, Ehud
Abstract
A composition comprising an emulsion comprising a plurality of particles is provided. An article comprising a substrate, and a plurality of particles comprising a void core and a shell, wherein the plurality of particles are in the form of a coating layer on the substrate is provided. Further, a method for coating a substrate is provided.
B32B 3/26 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layerLayered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a layer with cavities or internal voids
B32B 19/04 - Layered products essentially comprising natural mineral fibres or particles, e.g. asbestos, mica next to another layer of a specific substance
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Salzer, Yael
Lidor, Guy
Rosenfeld, Lavi
Shaked, Ben
Reshef, Liad
Grinshpun, Joseph
Honig, Hen
Shaked, Roi
Abstract
An animal-monitoring apparatus has a housing that engages with an animal's nasal cavities via first and second arm members that each have an animal engagement portion insertable into one of the nasal cavities. A sensor arrangement is carried by the housing and has a thermal sensor and optical sensor(s). At least a portion of the thermal sensor is located in the animal engagement portion of the first or second arm member. The optical sensor(s) is/are located at a terminating end of the animal engagement portion of the first or second arm member. A processing arrangement communicates with the housing and is associated with the sensor arrangement. The processing arrangement processes signals from the thermal sensor to calculate at least one respiration-related bioparameter of the animal, and processes signals from the optical sensor(s) to calculate at least one blood circulation-related bioparameter of the animal.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Raveh, Eran
Vitoshkin, Elena
Abstract
The present disclosure provides a method in an agrivoltaic system comprising photovoltaic panels disposed to cast a shadow on plants when irradiated by sunlight. The photovoltaic panels are controllable for adjusting said shadow. The method comprises obtaining a comparison signal indicative of a comparison between a temperature of ambient air and a temperature of the plants; and controlling one or more of said photovoltaic panels to adjust the shadow cast by said one or more photovoltaic panels on the plants using said comparison signal.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (Israel)
Inventor
Sal-Man, Neta
Vernick, Sefi
Wine, Yariv
Abstract
The present invention relates to diagnostic platform. More specifically, the invention relates to a dual platform composed of a detection and quantification unit and a characterization unit, systems, kits, methods and uses thereof in detection, quantification and characterization of pathogens, the system comprising monoclonal-antibody-based biosensor chips, for detection and/or quantification of pathogens in a sample, and substrate-based biosensor chips for enzymatically profiling the pathogen in the sample.
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
C12Q 1/34 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase
25.
BACTERIUM, MICROBIAL CONSORTIUM COMPRISING THE SAME AND USES THEREOF
C12N 9/24 - Hydrolases (3.) acting on glycosyl compounds (3.2)
C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
C12P 19/14 - Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase, e.g. by alpha-amylase
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Posmanik, Roy
Graber, Ellen Ruth
Bar, Maya
Abstract
The present disclosure provides a method for processing coffee waste, the method comprises (i) subjecting an aqueous mixture comprising parti culated coffee waste and an aqueous medium to hydrothermal conditions, to obtain a coffee waste slurry including particulates; and (ii) separating at least part of the particulates from said coffee waste slurry, to obtain a coffee waste product; wherein, said hydrothermal conditions comprise a temperature above 170°C; and a pressure equal or above 1 MPa. Further provided by the present disclosure is a coffee waste product comprising in an aqueous sample volume of 1 liter any one or combination of the following characteristics: total antioxidant capacity from about 6000 and about 8000 mg Fe(II) eq., total phenolic content from about 2000 and about 3000 mg gallic acid (GA) eq., and total furfural compounds content from about 1000 ppm and 2000 ppm. Finally, the presently disclosed subject matter provides a method comprising applying to a plant or a plant soil an amount of disclosed coffee waste product.
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (Israel)
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Ori, Naomi
Israeli, Alon
Bar, Maya
Abstract
The present invention, is directed to a method for selecting an improved genetically modified Solarium plant, the method including: determining the presence of at least one inactive allele of auxin responsive factor (ARF) 8 gene in the genome of the genetically modified Solanum plant or a part derived therefrom; and (b) selecting a genetically modified Solanum plant determined as having a genome including the at least one inactive allele of ARF8 gene, wherein the improvement is at least any one of: (i) increased yield; (ii) increased resistance to a pathogen; (iii) earlier fruit setting; and (iv) any combination of (i) to (iii), compared to a wild-type variant of said Solanum plant, thereby, selecting an improved genetically modified Solanum plant.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE] (Israel)
ISRAEL OCEANOGRAPHIC & LIMNOLOGICAL RESEARCH LTD. (Israel)
Inventor
Ron, Michael
Shirak, Andrey
Seroussi, Eyal
Rosenfeld, Hanna
Meiri Ashkenazi, Iris
Abstract
The invention relates to a sex determination (SD) marker of a male Mugilidae fish comprising a nucleic acid sequence corresponding to a sequence of a Follicle-stimulating hormone receptor (FSHR) gene of said fish and including at least one male (Y) specific nucleotide difference when compared to a corresponding sequence on a FSHR gene of a female Mugilidae fish. The invention further concerns uses of this sex determination marker in methods of early sex determination in a Mugilidae fish, methods of sex-reversal of a Mugilidae fish prior to appearance of a sex phenotype, and methods for producing a mono-sex population of Mugilidae fishes.
A61K 31/568 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstane, testosterone
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Eltzov, Evgeni
Kaur, Manpreet
Abstract
The present invention teaches a bioassay module for detection of pathogenic microorganisms comprising: food specimen deposit element; indicator layer comprising dye; enzymatically digestible substrate layer, forming a barrier between the food specimen deposit element and indicator layer; isolation layer, separating the enzymatically digestible substrate layer from layers underlying the enzymatically digestible substrate layer; separation layer; absorption layer to absorb and display the indicator; wherein the layers are disposed from bottom to top the absorption layer, the separation layer, the indicator layer, the isolation layer, the enzymatically digestible substrate layer, the food specimen deposit element, and enzymatically digestible substrate layer is liquefiable and perforable by enzymes secreted by the pathogenic microorganism in contaminated food disposed in the food specimen deposit element, the digested substrate layer is flowable to the indicator layer via the isolating layer, the liquefied dye flowable to the absorption layer and visible at least from the top layer.
C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
G01N 33/483 - Physical analysis of biological material
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (Israel)
Inventor
Shemesh, Moshe
Rajasekharan, Satish Kumar
Steinberg, Doron
Abstract
A method of generating a biofilm of nomadic bacteria. The method comprises: (a) culturing the nomadic bacteria in an acidic environment under conditions that promote generation of a V-type structure of the nomadic bacteria; and subsequently (b) culturing said nomadic bacteria having a V-type structure on an adherent surface, thereby generating the biofilm comprising the nomadic bacteria. Conditioned media of nomadic bacteria are also disclosed and uses thereof.
A61K 35/744 - Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Mechrez, Guy
Ment, Dana
Ananth Mani, Karthik
Yaakov, Noga
Abstract
Provided herein is a composition comprising a Pickering emulsion comprising a plurality of core-shell particles encapsulating a microbial cell and/or a spore thereof. Furthermore, a method for controlling a pest on or within a plant or at the area under cultivation is provided.
A01N 25/26 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
A01N 55/02 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
A01N 61/02 - Mineral oilsTar oilsTarDistillates, extracts or conversion products thereof
A01N 63/20 - BacteriaSubstances produced thereby or obtained therefrom
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Ezra, David
Deutsch, Ynon
Abstract
The present invention, in some embodiments thereof, is directed to an antimicrobial composition including 8-Nonenoic acid, 4-cumylphenol, an analog thereof, or any combination thereof, and a method of using same, such as for preventing or treating a pathogenic infection in an aquatic organism.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Lapidot, Moshe
Levin, Ilan
Abstract
Methods of producing a tomato plant exhibiting tolerance or resistnce to ToBRFV are provided. Also provided are methods of identifying such plants and plants derived thereby as well as processed products comprising same.
A01H 6/82 - Solanaceae, e.g. pepper, tobacco, potato, tomato or eggplant
C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
C12Q 1/683 - Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Mechrez, Guy
Ananth Mani, Karthik
Yaakov, Noga
Abstract
A composition comprising modified multifunctional inorganic particles is provided. An article or composite comprising a thermoplastic polymer or a plurality of immiscible polymers and the modified particles homogenously distributed therewithin is provided. Further, a method for preparing the composites is provided.
B82B 3/00 - Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
B82B 1/00 - Nanostructures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Shtenberg, Giorgi
Nirala, Narsingh R.
Abstract
A method and system for early detection of Bovine Mastitis (BM) uses enhanced chemiluminescence (CL) to determine Haptoglobin (Hp) levels in highly diluted milk samples. The samples are placed in the wells of one or more bio-functionalized Hemoglobin (Hb) modified CL assay plates. Hp-Hb binding occurs in those samples containing Hp. After a first pre-determined time duration, the wells are treated with a CL solution containing luminol and peroxide, and a colloidal suspension of crosslinked nanoparticles. After a second pre-determined time duration, the CL intensity approaches a steady state value. A processor analyzes CL images provided by a camera in order to measure CL intensity and to determine an estimate of Hp level in each well, based on a pre-determined regression curve. The processor then forms a BM clinical diagnosis by combining the estimated HP levels from wells with different milk sample dilutions.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Alchanatis, Victor
Abstract
A controllable valve unit and corresponding irrigation system are described. The controllable valve is configured for use with an irrigation dripper positioned along an irrigation line. The controllable valve unit is configured to be selectively shiftable between a first open position and a second closed position to selectively control flow of irrigation therethrough. The controllable valve unit comprises at least one magnet, enabling switching of said valve between said first open and said second closed positioned by selective application of magnetic field in its surroundings.
A01G 25/02 - Watering arrangements located above the soil which make use of perforated pipe-lines or pipe-lines with dispensing fittings, e.g. for drip irrigation
F16K 31/06 - Operating meansReleasing devices electricOperating meansReleasing devices magnetic using a magnet
37.
NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND CANNABINOIDS AND USES THEREOF
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Koltai, Hinanit
Shalev, Nurit
Abstract
Non-steroidal anti-inflammatory drugs and cannabinoids are provided. Accordingly, there is provided an article of manufacture comprising as active ingredients a non-steroidal anti-inflammatory drug and a composition comprising phytocannabinoids, wherein the phytocannabinoids comprise at least 80 % CBD and at least one of CBG and THCV. Also provided are methods of using same in the treatment of disease e.g. inflammation, pain and/or fever. Also provided is an article of manufacture comprising as active ingredients a steroid and a composition comprising phytocannabinoids; and its use in therapy.
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
A61K 31/56 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids
A61K 31/58 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (USA)
UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (USA)
Inventor
Raveh, Eran
Albrecht, Ute
Bowman, Kim D.
Tietel, Zipora
Abstract
A composition comprising an HLB -susceptible or tolerant citrus rootstock grafted with an HLB -tolerant or resistant citrus interstock is provided. Also provided are plants comprising same and uses thereof in citrus growth.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Shtenberg, Giorgi
Kumar, Nanda
Blum, Shlomo
Abstract
A label-free optical biosensing system and method provide high sensitivity and specificity for in situ detection and activity estimation of serotypes, such as Botulinum Neurotoxins (BoNT). Pre-fabricated thin-film support structures are treated with a competitive immunoassay coupled to a biochemical cascade reaction, which provides optical signal amplification. When the thin-film support structures receive a target analyte and are exposed to polychromatic light, reaction products cause a change in average refractive index which appears in reflectivity spectra measured by an optical interferometer. Optical signal amplification enables a linear response for serotype concentrations of only a few picograms per millilitre, as well as a level-of-detection threshold of 5.0 picograms per millilitre or less. The specificity and selectivity of the method have been verified in studies using various combinations of different serotypes as a target analyte. Similarly, the serotype activity is estimated by an adjunct sensing platform.
G01N 21/45 - RefractivityPhase-affecting properties, e.g. optical path length using interferometric methodsRefractivityPhase-affecting properties, e.g. optical path length using Schlieren methods
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
40.
IN-LINE EARLY WARNING SYSTEM OF WATER CONTAMINATION WITH ORGANIC MATTER
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Klapp, Iftach
Sela, Shlomo
Borisover, Mikhail
Rosenfeld, Lavi
Abstract
An inline early warning system of water contamination with fluorescence signature comprises: (a) an optical chamber embeddable into a water-supply system and having an internal passage configured for conducting a flow of water to be tested (b) a UV light source configured for illuminating the flow of water via the entrance window and excite tryptophan-like fluorescence at 280 nm and humic-like-fluorescence at 320 - 360 nm; (c) an optical sensor arrangement configured for sensing the tryptophan-like fluorescence and humic-like-fluorescence emissions at 350 nm and 400 to 480 nm via the exit window, respectively; (d) a UV light source configured for illuminating the flow of water via the entrance window and excite natural fluorescence of water contamination; (e) a non-optical sensor arrangement; (f) an acquisition and control unit configured for measuring tryptophan-like fluorescence and humic-like-fluorescence emissions and (g) a processor configured processing obtained measured data.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Bechar, Avital
Bloch, Victor
Finkelshtain, Roee
Abstract
A human-robot system and method for performing an agricultural task, the system including: a robotic manipulator with an agricultural tool coupled to an end effector thereof; an imaging device adapted to capture imagery of a target, the imaging device mechanically coupled to the end effector; a laser distance sensor adapted to measure a distance between the manipulator and the target, the laser distance sensor mechanically coupled to the end effector and collocated with the imaging device; and a control unit including: a processing unit, a monitor and a human-machine interface (HMI), wherein the processing unit is configured to display the imagery on the monitor and to receive markings from the HMI and calculate a trajectory for the manipulator to perform the agricultural task with the tool.
The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Institute) (Israel)
Inventor
Yermiyahu, Uri
Schmilovitch, Zeev
Alchanatis, Victor
Rapaport, Tal
Abstract
A method of measuring element concentration in plant leaves comprises steps of: (a) gathering leaves of plants to be tested; (b) conditioning specimens of said leaves; (c) obtaining raw count-per-second XRF datasets of said specimens; (d) obtaining raw NIR datasets of said specimens; (e) obtaining raw analytical datasets; and (f) assessing concentrations of minerals within said specimens on the basis of said count-per-second XRF, NIR and analytical datasets. The aforesaid method further comprises steps of obtaining white reference radiance datasets and normalizing said raw NIR datasets on the basis thereof and providing NIR reflectance datasets.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
G01N 21/3563 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing solidsPreparation of samples therefor
G01N 21/68 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence using high frequency electric fields
G01N 21/84 - Systems specially adapted for particular applications
G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
43.
USE OF ATTENUATED TOMATO BROWN RUGOSE FRUIT VIRUS FOR PROTECTING CROPS AGAINST SAME VIRUS
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Dombrovsky, Aviv
Smith, Elisheva
Lachman, Oded
Luria, Neta
Abstract
Tm-222 resistant tomato varieties against ToBRFV infection and reducing disease symptoms. Also provided are methods of protecting agricultural crops such as tomatoes against said virus.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Koltai, Hinanit
Shalev, Nurit
Peeri, Hadar
Abstract
Compositions capable of reducing viability, inducing cell cycle arrest and/or reducing proliferation and/or migration of Glioblastoma multiforme (GMB) and ovarian cancer cells and methods of use thereof are provided. The compositions and uses thereof comprise phytocannabinoids.
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/454 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Mechrez, Guy
Ananth Mani, Karthik
Dombrovsky, Aviv
Abstract
A composition comprising an emulsion comprising a plurality of core-shell particles is provided. Furthermore, an insecticidal composition and use thereof so as to prevent or arrest growth of an insect or aphid is also provided. Further, a method for preventing or inhibiting growth of an insect or aphid on a plant or within the area under cultivation is provided.
A01N 25/02 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
B01J 13/00 - Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided forMaking microcapsules or microballoons
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Shemesh, Moshe
Kroupitski, Yulia
Sela, Shlomo
Abstract
A method of generating an antimicrobial agent is disclosed. The method comprises: (a) culturing Bacillus cells in a medium under conditions effective to allow secretion of at least one antimicrobial agent into the medium; and (b) purifying the at least one antimicrobial agent from the medium to generate a purified preparation comprising the at least one antimicrobial agent. Uses of the antimicrobial agents secreted from the Bacillus cells are also disclosed.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
BAR ILAN UNIVERSITY (Israel)
Inventor
Mechrez, Guy
Mani, Karthik Ananth
Maayan, Mor
Banin, Ehud
Abstract
A composition comprising an emulsion comprising a plurality of particles is provided. An article comprising a substrate, and a plurality of particles comprising a core and a shell, wherein the plurality of particles are in the form of a coating layer on the substrate is provided. Further, a method for coating a substrate is provided.
C08J 9/00 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof
C08J 9/28 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Bar, Maya
Leibman, Meirav
Abstract
This invention is related to a mutated plant line that harbors an impaired LeEIXl (Lycopersicon esculentum ethylene inducing xylanase receptor 1) gene. The said mutated plant has an increased defense response and a reduction in disease levels upon pathogen exposure compared to a non-mutated plant of the same population. This invention is also related to the method for increasing a plant defense response and for reducing plant diseases levels, comprised by (a) designing at least one nucleic acid sequence configured to targeting and impairing a plant's LeEIXl gene, (b) applying a gene editing process utilizing said at least one nucleic acid sequence, (c) obtaining at least one mutant plant line, harboring an impaired LeEIXl gene, (d) growing said plant, and (e) inoculating said plant with at least one bacterial biological control agent.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
RAMOT AT TEL AVIV UNIVERSITY LTD. (Israel)
Inventor
Maya, Bar
Leibman, Meirav
Adi, Avni
Abstract
This invention is related to a double mutant plant line that harbors impaired NRC4a (NLR required for cell death) and NRC4b genes. The said double mutant plant has an increased defense response and a reduction in disease levels compared to a non-mutated or a single mutation mutated plant of the same population. This invention is also related to the method for increasing a plant defense response and for reducing plant diseases levels, comprised by (a) configuring one or more nucleic acid sequences to target and impair at least two plant NRC (NLR required for cell death) or NRC ortholog genes, (b) applying a gene editing process utilizing said one or more nucleic acid sequences, (c) obtaining at least one double mutant plant line, harboring two impaired NRC (NLR required for cell death) genes, and (d) growing said plant.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Rozenstein, Offer
Tanny, Josef
Kaplan, Grigorii
Abstract
A system and method for estimating a crop coefficient vector (CCV) uses one or more remote sensors that provide multispectral images of a crop growing area. The CCV includes a crop coefficient estimate, KC, and at least one of a leaf area index estimate, LAI, and a crop height estimate, CH. The system includes one or more remote sensing subsystems (RSS); a preprocessor configured to generate harmonized spectral data from multispectral images; a vegetation index (VI) processor to calculate VIs from the harmonized spectral data; a storage medium containing pre-determined regression coefficients; and a CCV processor configured to calculate an estimated CCV. The RSS includes an image sensor mounted on a platform which may be airborne, such as an unmanned aerial vehicle, or space-borne, such as an orbiting satellite. The image sensor includes visual and/or infrared bands.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Bar, Maya
Abstract
A method for improving a plant trait, comprising steps of: a. obtaining a plant; and b. inoculating said plant with at least one bacterium having at least one of sequences SEQ ID NO:l- SEQ ID NO: 17, as disclosed in the sequence listing of said application, germinating the seed and growing the plant A bacterial formulation useful for the method is disclosed comprising at least one bacterium having at least one of sequences SEQ ID NO:l- SEQ ID NO: 17, as disclosed in the sequence listing of said application.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Assouline, Shmuel
Narkis, Kfir
Abstract
A floating element configured for inhibiting wind flow across a body of liquid so as to suppress liquid evaporation including: a lattice-like structure configured for floating in the body of liquid, the lattice-like structure includes a plurality of elongated portions and joints and a plurality of inner connections configured for creating a plurality of substructure components joined to one another so as to form at least substantially a cubic structure.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Koltai, Hinanit
Shalev, Nurit
Abstract
A bio-ink comprising: (a) at least one polysaccharide; (b) at least one structural protein; and (c) fibrinogen, wherein the polysaccharide is selected from a group consisting of Sodium alginate Chitosan, Hyaluronic acid, Gellan gum, Dextran, Agarose, Poly(ethylene glycol), Pluronic and Carrageenan and the structural protein is selected from a group consisting of Gelatin, Collagen Vitronectin, Laminins and Fibronectin.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Alkan, Noam
Oren-Shamir, Michal
Elad, Yigal
Maurer, Dalia
Feygenberg, Oleg
Abstract
The present invention is directed to methods for improving flavor, coloration, curing, or any combination thereof, of a plant material, including pre-harvest or post-harvest treatment with an effective amount of an aromatic amino acid or an analog thereof.
A01N 37/44 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio-analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio-analogue of a carboxylic group, e.g. amino-carboxylic acids
A01N 25/00 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests
55.
STERILE AVIAN EMBRYOS, PRODUCTION AND USES THEREOF
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Cinnamon, Yuval
Ben-Tal Cohen, Enbal
Abstract
The present disclosure relates to deoxyribonucleic acid (DNA) editing agents, and their use in preparing DNA-edited cells and birds. The present disclosure further relates to gene- edited or genetically modified avians and gene-edited or genetically modified avian primordial germ cells (PGCs) for producing gene-edited or genetically modified avians (birds) that can serve as surrogate hosts for donor PGCs. The present disclosure further relates to methods for producing avian strains that can produce viable embryos and offspring, in both sexes, and for their subsequent use as surrogate hosts for donor PGCs.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (Israel)
SAPIR ACADEMIC COLLEGE (Israel)
ACHVA ACADEMIC COLLEGE (Israel)
Inventor
Ment, Dana
Mendel, Zvi
Zaritsky, Arieh
Kushmaro, Ariel
Barak, Zeev
Sitrit, Yaron
Ben-Dov, Eitan
Mondaca, Lilach Lily
Abstract
The present invention provides protein toxins, their encoding genes, various combinations thereof, cells comprising them, and their use for controlling pests.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
B.G. NEGEV TECHNOLOGIES & APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (Israel)
Inventor
Klapp, Iftach
Kalantar, Aharon
Dashuta, Artium
Edan, Yael
Gur, Amit
Abstract
A method of in-situ estimating volume and mass of a plurality of objects comprises: (a) obtaining at least one image including said plurality of objects; (b) detecting said of objects within said image; (c) individually contouring said objects; (d) individually modelling shapes of said objects; and (e) individually estimating a volume and mass of said objects.
G06V 10/75 - Organisation of the matching processes, e.g. simultaneous or sequential comparisons of image or video featuresCoarse-fine approaches, e.g. multi-scale approachesImage or video pattern matchingProximity measures in feature spaces using context analysisSelection of dictionaries
58.
COMPOSITIONS AND METHODS FOR THE TREATMENT OF UROTHELIAL CANCER
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. (Israel)
Inventor
Koltai, Hinanit
Anis, Omer
Abstract
Compositions capable of reducing viability, initiating apoptosis, inducing cell cycle arrest and/or reducing migration of urothelial carcinoma cells and methods of use thereof are provided. The compositions and uses thereof comprise cannabinoids.
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
59.
COMPOSITIONS OF MICROORGANISMS AND METHODS OF USING SAME
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Ezra, David
Deutsch, Ynon
Gur, Lior
Abstract
The present invention, in some embodiments thereof, is directed to an artificial composition including microorganisms, and a method of using same, such as for preventing or treating a pathogenic infection in an aquatic organism.
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
A01N 63/30 - Microbial fungiSubstances produced thereby or obtained therefrom
A01N 25/00 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests
60.
COMPOSITION OF PREDATORY NEMATODES AND METHODS OF USING SAME
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Brown, Sigal
Oren, Orly
Spiegel, Yitzhak
Mazar, Yinon
Ehlers, Ralf-Udo
Abstract
The present invention is directed to a synthetic nematocidal composition comprising a mixture of developmental stages of a predatory nematode, and methods of using same, such as for protecting a plant from a plant-parasitic nematode.
A01N 25/00 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
61.
MONOCLONAL ANTIBODY-BASED BIOSENSOR FOR POINT-OF-CARE DETECTION OF TYPE III SECRETION SYSTEM EXPRESSING PATHOGENS
B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (Israel)
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Wine, Yariv
Hillman, Yaron
Even, Dan
Lustiger, Dan
Sal-Man, Neta
Braverman, Dor
Gershberg, Jenia
Vernick, Sefi
Ashur, Idan
Abstract
The present disclosure relates to a biosensor chip device usable for identifying and/or quantifying a target in a sample by electrochemical impedance spectroscopy (EIS) analysis. The biosensor chip device disclosed herein comprises a plurality of electrodes connectable to at least one electronic device, wherein, at least one of the electrodes is a working electrode connected directly or indirectly to at least one target binding site and/or moiety. It should be noted that the target binding site and/or moiety specifically binds the at least one target or any component thereof. Still further, in some embodiments, the plurality of electrodes is configured for electrochemical impedance spectroscopy (EIS) analysis of the sample. More specifically, the invention relates to monoclonal-antibody-based biosensor chip, devices, kits and diagnostic methods for detection of pathogens expressing Type III secretion system (T3SS) in a sample.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Vernick, Sefi
Ogungbile, Abraham Oluwafemi
Shapiro, Orr H.
Abstract
The invention relates to immunological -based biosensor chip systems, devices, kits and diagnostic methods for detection, quantification and/or monitoring of at least one target compound, specifically, at least one small molecule compound, specifically, cyanotoxins in a sample. The present disclosure relates to a biosensor chip system usable for identifying and/or quantifying and/or monitoring at least one target in a sample. More specifically, the system comprises at least one of: at least one first and at least one second chip devices. It should be noted that the first chip device comprises a first plurality of electrodes connectable to at least one electronic device. It should be further noted that the first plurality of electrodes is configured for electrochemical impedance spectroscopy (EIS) analysis of the sample. The second chip device comprises a second plurality of electrodes connectable to at least one electronic device. The second plurality of electrodes is configured for electrochemical voltammetry or amperometry analysis of said sample.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Or, Etti
Abstract
In one aspect of the invention, provided herein an agricultural composition comprising a synergistically effective amount of a sulfide compound and of a surfactant. Further, a method of using the composition of the invention such as for enhancing or inducing bud break in a plant, is provided.
A01N 31/00 - Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
A01N 25/30 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Biran, Jakob
Cnaani, Avner
Segev, Adi
Slosman, Tatiana
Abstract
A fish of a tilapia genus comprising a loss-of-function mutation in a slc45a2 gene, wherein the mutation is in a homozygous form, and wherein the loss-of-function mutation results in an albino-red phenotype of the fish is disclosed. Methods of generating the fish are also disclosed.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Spiegelman, Ziv
Hak, Hagit
Loeb Ezra, Joseph
Sherman, Yifat
Abstract
A tomato plant or a part thereof is disclosed. The plant expresses a Tm-22 protein having an amino acid sequence which renders the plant resistant to tomato brown rugose fruit virus (ToBRFV). Methods of generating same are also disclosed. Products generated therefrom are described.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Koltai, Hinanit
Shalev, Nurit
Namdar, Dvora
Mechrez, Guy
Abstract
Cannabinoidal compositions for the treatment of disease are provided. Accordingly, there is provided a method of treating a disease that can benefit from activating macrophages comprising administering to the subject a therapeutically effective amount of a composition comprising a cannabis derived fraction comprising phytocannabinoids, wherein said phytocannabinoids comprise at least 80 % CBD and at least one of CBG and THCV. Also provided is a method of treating a cytokine storm comprising administering to the subject a therapeutically effective amount of a synthetic composition comprising phytocannabinoids, wherein said phytocannabinoids comprise at least 80 % CBD and at least one of CBG and THCV.
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Koltai, Hinanit
Namdar, Dvora
Abstract
Described herein are a method of preparing a vegetable oil, comprising pressing a non- fruit tissue of a date palm offshoot, as well as a vegetable oil and a polysaccharide-containing fraction obtained by such a method. Further described herein is an oil comprising esters of fatty acids, wherein at least 10 weight percent of the fatty acids are linolelaidic acid, as well as compositions comprising a variety of ingredients, such as saccharides and amino acids, as characterized herein, and a method of isolating dihydrouracil from an oil and/or composition described herein. Further described is a method of preparing a vegetable oil, comprising pressing date kernel tissue.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Tietel, Zipora
Tsror, Leah
Abstract
The present application discloses a method for the early detection of bacterial diseases of potato tubers. More particularly, the present application discloses a method for identifying bacteria which cause blackleg and tuber soft rot diseases in potato tubers based on the identification of unique patterns of volatile compounds. The method disclosed herein can serve for the differentiation of non-inoculated samples from inoculated samples, distinguishing and identifying inoculation by different bacterial genera (Pectobacterium and Dickeya spp), different bacterial species and different bacterial sub-species. The detection relies on specific combinations of volatile compounds associated with each of the above-mentioned groups, which can serve as an applicable tool to detect tuber pathologies in storage rooms and shipments.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
Inventor
Alkan, Noam
Poverenov, Elena
Saidi, Lilach
Maurer, Dalia
Feygenberg, Oleg
Abstract
The present invention is related to liquid compositions, kits and to methods for using thereof such as for reducing pathogen load or for prolonging shelf-life of the edible matter.
A01N 37/44 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio-analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio-analogue of a carboxylic group, e.g. amino-carboxylic acids
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (Israel)
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (Israel)
Inventor
Shemesh, Moshe
Galili, Shmuel
Reifen, Ram
Abstract
BacilliBacilli class is disclosed. The method comprises: (a) adding the bacteria to a medium comprising pasteurized starch fibers of a legume of a leguminous plant, and (b) culturing the bacteria under conditions that promote generation of a biofilm of the bacteria on the starch fibers.
C12P 1/04 - Preparation of compounds or compositions, not provided for in groups , by using microorganisms or enzymesGeneral processes for the preparation of compounds or compositions by using microorganisms or enzymes by using bacteria
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE]) (Israel)
Inventor
Ron, Michael
Shirak, Andrey
Seroussi, Eyal
Rosenfeld, Hanna
Meiri Ashkenazi, Iris
Abstract
The invention relates to a sex determination (SD) marker of a male Mugilidae fish comprising a nucleic acid sequence corresponding to a sequence of a Follicle-stimulating hormone receptor (FSHR) gene of said fish and including at least one male (Y) specific nucleotide difference when compared to a corresponding sequence on a FSHR gene of a female Mugilidae fish. The invention further concerns uses of this sex determination marker in methods of early sex determination in a Mugilidae fish, methods of sex-reversal of a Mugilidae fish prior to appearance of a sex phenotype, and methods for producing a mono-sex population of Mugilidae fishes.
B07C 5/342 - Sorting according to other particular properties according to optical properties, e.g. colour
G01N 21/25 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 21/359 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
G01N 21/62 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
G01N 21/84 - Systems specially adapted for particular applications