A system includes an apparatus configured to mix water, an acid/electrolyte concentrate, an osmotic concentrate, and a neutralizing buffer to produce a supply dialysate, a supply chamber configured to store the supply dialysate, a first filter that is configured to receive the supply dialysate from the supply chamber and to remove contaminants from the supply dialysate, a second filter, and one or more valves that: in a first configuration allow the second filter to receive a spent dialysate from the patient drain line to capture biological components from the spent dialysate such that the spent dialysate is dispensed via the system drain line, and in a second configuration allow the second filter to receive the supply dialysate to remove further contaminants from the supply dialysate such that the supply dialysate and the biological components are dispensed via the patient fill line.
In a fluorometer diagnostic mode, a system moves water and a fluorescent probe material from a mixing chamber to a fluorometer. In a filter diagnostic mode, the system moves water and a fluorescent probe material from the mixing chamber into an inlet such that (i) a first portion of the water and the fluorescent probe material moves out of a bypass outlet and back to the mixing chamber and (ii) a second portion of the water moves through the filter to the fluorometer. In a dialysate dispensing mode, the system moves a dialysate and the fluorescent probe material from the mixing chamber into the inlet such that (i) a first portion of the dialysate and the fluorescent probe material moves out of the bypass outlet and back to the mixing chamber and (ii) a second portion of the dialysate moves through the filter and to the fluorometer.
A system includes a housing, a water supply line, a dialysate supply line, a drain line, and a patient line each extending from the housing. The system also includes a first port, a second port, a third port, and a fourth port that are accessible from outside the housing. The first port can connect to the water supply line, the second port can connect to the dialysate supply line, the third port can connect to the drain line, and the fourth port can connect to the patient line. The system also includes a first flush line, a second flush line, and a third flush line each contained within the housing. The first flush line terminates at the first port and the third port, the second flush line terminates at the second port, and the third flush line terminates at the fourth port and at the drain line within the housing.
Peritonitis sensors, including peritonitis sensors for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, an APD system includes a disposable set, a portion of which is at least partially aligned with a peritonitis sensor. The peritonitis sensor can be configured to capture one or more peritonitis measurements from the solution in the disposable set. The APD system can determine whether one or more peritonitis measurements indicate the presence of peritonitis in a patient from which the solution is drained. In some embodiments, if the APD system determines that one or more peritonitis measurements indicate peritonitis, the APD system can alert a user of the system to the presence of peritonitis in the patient.
Transfer sets with filters, including transfer sets with filters for peritoneal dialysis (PD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, a transfer set includes a first connector configured to be coupled to a disposable set of a PD system, a second connector configured to be coupled to a catheter of the PD system, and a fluid channel extending between the first connector and the second connector. The transfer set further includes a filter positioned within the fluid channel and configured to filter contaminants from solution flowing within the fluid channel between the first connector and the second connector. In some embodiments, the transfer set further includes a one-way valve positioned between the filter and the second connector and configured to prevent fluid from flowing through the one-way valve in a direction toward the filter.
Pressure sensors, including optical pressure sensors for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, an APD system includes a diaphragm positioned over an opening in a cavity of a disposable set. The diaphragm has an outer surface and an inner surface opposite the outer surface. The diaphragm is configured to deform in response to a force applied against the diaphragm due to pressure of fluid within the cavity. The APD system further includes a pressure sensor configured to measure a pressure of the fluid within cavity. The pressure sensor includes a light source and a photosensor. The light source is configured to irradiate the outer surface of the diaphragm with light, and the photosensor is configured to measure an amount of the light that is reflected off of the outer surface of the diaphragm and directed
Identification Systems, Including Anti-Counterfeit and Anti-Reuse Identification Systems for Automated Peritoneal Dialysis Systems, and Associated Systems, Devices, and Methods
Identification systems, including anti-counterfeit and anti-reuse identification systems for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, an APD system includes an identification system having at least one identification sensor configured to read device identifiers associated with disposable components of the APD system. The disposable components can include cassettes or source bags containing dialysate solution. In some embodiments, the identification system can (a) compare a device identifier of a disposable component to a whitelist of valid device identifiers, (b) determine whether the device identifier is valid, unused, and/or non-expired, and/or (c) based on the determination, determine whether to use the disposable component to execute an exchange treatment. In some embodiments, the APD system can include (i) a mount configured to receive the disposable component and (ii) a plunger mechanism configured to physically damage the disposable component after it has been used.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
10.
PRESSURE SENSORS, INCLUDING PRESSURE SENSORS FOR AUTOMATED PERITONEAL DIALYSIS SYSTEMS, AND ASSOCIATED SYSTEMS, DEVICES, AND METHODS
Pressure sensors, including pressure sensors for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, an APD system includes a diaphragm positioned over an opening in a disposable set that includes one or more fluid lines. The diaphragm is affixed to the disposable set about a periphery of the opening. The APD system further includes a pressure sensor configured to measure a pressure of fluid flowing through the disposable set. The pressure sensor includes a load cell and an indenter. The indenter can be moveable along an axis such that, when the diaphragm is aligned with the axis, a convexly curved surface of the indenter can be positioned against the diaphragm. When the indenter is contacting the diaphragm, the load cell can measure a force applied to the load cell by the diaphragm and/or by the fluid flowing through the disposable set.
Damping devices, including damping devices for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, a damping device includes a body portion, a first membrane, and a second membrane. The body portion can include a first side, a second side opposite the first side, an inlet, and a cavity fluidly coupled to the inlet. The cavity can be defined at least in part by a lumen in the body portion extending from the first side to the second side. The first membrane can be affixed to the first side of the body portion such that the first membrane hermetically seals the cavity at the first side. The second membrane can be affixed to the second side of the body portion such that the second membrane hermetically seals the cavity at the second side.
A system includes an apparatus configured to mix water, an acid/ electrolyte concentrate, an osmotic concentrate, and a neutralizing buffer to produce a supply dialysate, a supply chamber configured to store the supply dialysate, a first filter that is configured to receive the supply dialysate from the supply chamber and to remove contaminants from the supply dialysate, a second filter, and one or more valves that: in a first configuration allow the second filter to receive a spent dialysate from the patient drain line to capture biological components from the spent dialysate such that the spent dialysate is dispensed via the system drain line, and in a second configuration allow the second filter to receive the supply dialysate to remove further contaminants from the supply dialysate such that the supply dialysate and the biological components are dispensed via the patient fill line.
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
A61M 60/113 - Extracorporeal pumps, i.e. the blood being pumped outside the patient’s body incorporated within extracorporeal blood circuits or systems in other functional devices, e.g. dialysers or heart-lung machines
A61M 60/37 - Haemodialysis, haemofiltration or diafiltration
A61M 60/508 - Electronic control means, e.g. for feedback regulation
Transfer sets with filters, including transfer sets with filters for peritoneal dialysis (PD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, a transfer set includes a first connector configured to be coupled to a disposable set of a PD system, a second connector configured to be coupled to a catheter of the PD system, and a fluid channel extending between the first connector and the second connector. The transfer set further includes a filter positioned within the fluid channel and configured to filter contaminants from solution flowing within the fluid channel between the first connector and the second connector. In some embodiments, the transfer set further includes a one-way valve positioned between the filter and the second connector and configured to prevent fluid from flowing through the one-way valve in a direction toward the filter.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
A61M 39/00 - Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
B01D 61/00 - Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltrationApparatus, accessories or auxiliary operations specially adapted therefor
B01D 71/00 - Semi-permeable membranes for separation processes or apparatus characterised by the materialManufacturing processes specially adapted therefor
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
Identification systems, including anti-counterfeit and anti-reuse identification systems for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, an APD system includes an identification system having at least one identification sensor configured to read device identifiers associated with disposable components of the APD system. The disposable components can include cassettes or source bags containing dialysate solution. In some embodiments, the identification system can (a) compare a device identifier of a disposable component to a whitelist of valid device identifiers, (b) determine whether the device identifier is valid, unused, and/or non-expired, and/or (c) based on the determination, determine whether to use the disposable component to execute an exchange treatment. In some embodiments, the APD system can include (i) a mount configured to receive the disposable component and (ii) a plunger mechanism configured to physically damage the disposable component after it has been used.
Pressure sensors, including optical pressure sensors for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, an APD system includes a diaphragm positioned over an opening in a cavity of a disposable set. The diaphragm has an outer surface and an inner surface opposite the outer surface. The diaphragm is configured to deform in response to a force applied against the diaphragm due to pressure of fluid within the cavity. The APD system further includes a pressure sensor configured to measure a pressure of the fluid within cavity. The pressure sensor includes a light source and a photosensor. The light source is configured to irradiate the outer surface of the diaphragm with light, and the photosensor is configured to measure an amount of the light that is reflected off of the outer surface of the diaphragm and directed toward the photosensor.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
G01L 7/00 - Measuring the steady or quasi-steady pressure of a fluid or a fluent solid material by mechanical or fluid pressure-sensitive elements
G01L 9/00 - Measuring steady or quasi-steady pressure of a fluid or a fluent solid material by electric or magnetic pressure-sensitive elementsTransmitting or indicating the displacement of mechanical pressure-sensitive elements, used to measure the steady or quasi-steady pressure of a fluid or fluent solid material, by electric or magnetic means
16.
PERITONITIS SENSORS, INCLUDING PERITONITIS SENSORS FOR AUTOMATED PERITONEAL DIALYSIS SYSTEMS, AND ASSOCIATED SYSTEMS, DEVICES, AND METHODS
Peritonitis sensors, including peritonitis sensors for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, an APD system includes a disposable set, a portion of which is at least partially aligned with a peritonitis sensor. The peritonitis sensor can be configured to capture one or more peritonitis measurements from the solution in the disposable set. The APD system can determine whether one or more peritonitis measurements indicate the presence of peritonitis in a patient from which the solution is drained. In some embodiments, if the APD system determines that one or more peritonitis measurements indicate peritonitis, the APD system can alert a user of the system to the presence of peritonitis in the patient.
Peritonitis sensors, including peritonitis sensors for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, an APD system includes a disposable set, a portion of which is at least partially aligned with a peritonitis sensor. The peritonitis sensor can be configured to capture one or more peritonitis measurements from the solution in the disposable set. The APD system can determine whether one or more peritonitis measurements indicate the presence of peritonitis in a patient from which the solution is drained. In some embodiments, if the APD system determines that one or more peritonitis measurements indicate peritonitis, the APD system can alert a user of the system to the presence of peritonitis in the patient.
Pressure sensors, including pressure sensors for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, an APD system includes a diaphragm positioned over an opening in a disposable set that includes one or more fluid lines. The diaphragm is affixed to the disposable set about a periphery of the opening. The APD system further includes a pressure sensor configured to measure a pressure of fluid flowing through the disposable set. The pressure sensor includes a load cell and an indenter. The indenter can be moveable along an axis such that, when the diaphragm is aligned with the axis, a convexly curved surface of the indenter can be positioned against the diaphragm. When the indenter is contacting the diaphragm, the load cell can measure a force applied to the load cell by the diaphragm and/or by the fluid flowing through the disposable set.
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
B01D 61/00 - Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltrationApparatus, accessories or auxiliary operations specially adapted therefor
F16K 7/12 - Diaphragm cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage with flat, dished, or bowl-shaped diaphragm
19.
PRESSURE SENSORS, INCLUDING PRESSURE SENSORS FOR AUTOMATED PERITONEAL DIALYSIS SYSTEMS, AND ASSOCIATED SYSTEMS, DEVICES, AND METHODS
Pressure sensors, including pressure sensors for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, an APD system includes a diaphragm positioned over an opening in a disposable set that includes one or more fluid lines. The diaphragm is affixed to the disposable set about a periphery of the opening. The APD system further includes a pressure sensor configured to measure a pressure of fluid flowing through the disposable set. The pressure sensor includes a load cell and an indenter. The indenter can be moveable along an axis such that, when the diaphragm is aligned with the axis, a convexly curved surface of the indenter can be positioned against the diaphragm. When the indenter is contacting the diaphragm, the load cell can measure a force applied to the load cell by the diaphragm and/or by the fluid flowing through the disposable set.
A61B 5/021 - Measuring pressure in heart or blood vessels
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
B01D 61/00 - Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltrationApparatus, accessories or auxiliary operations specially adapted therefor
F16K 7/12 - Diaphragm cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage with flat, dished, or bowl-shaped diaphragm
20.
ARTIFICIAL INTELLIGENCE AND/OR MACHINE LEARNING BASED SYSTEMS, DEVICES, AND METHODS FOR DESIGNING PATIENT PRESCRIPTIONS
Methods and systems for generating a prescription using an artificial intelligence or machine learning model are described herein. The method can include receiving, from a therapeutic machine, a new prescription request for a patient, the new prescription request including one or more data items associated with the patient and one or more data items associated with a treatment of the patient, and using the machine learning model to determine a recommended prescription for the patient based on the one or more data items associated with the patient and one or more data items associated with the treatment of the patient. The method can also include transmitting the recommended prescription to a medical professional for approval, and in response to receiving user input from the medical professional, generating a final prescription based on the received user input, and storing the final prescription for later transmittal to the therapeutic machine.
Damping devices, including damping devices for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, a damping device includes a body portion, a first membrane, and a second membrane. The body portion can include a first side, a second side opposite the first side, an inlet, and a cavity fluidly coupled to the inlet. The cavity can be defined at least in part by a lumen in the body portion extending from the first side to the second side. The first membrane can be affixed to the first side of the body portion such that the first membrane hermetically seals the cavity at the first side. The second membrane can be affixed to the second side of the body portion such that the second membrane hermetically seals the cavity at the second side.
patents
