A bifidobacterium enrichment agent and a use thereof in high-density fermentation. The components of the bifidobacterium enrichment agent include potassium carbonate, arginine, methionine, serine, vitamin C, vitamin B1, vitamin B5, thymine, and calcium pantothenate. The bifidobacterium enrichment agent is added to a basal medium for high-density fermentation, so that the proliferation performance of bifidobacteria can be significantly improved, and the production efficiency can be improved, providing the possibility of preparing a highly active bifidobacterium fermentation liquor, and also providing support for the subsequent preparation and application of bacterial agents.
C12N 1/38 - Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factorsStimulation of growth by removal of a chemical compound
An adjustable condensation apparatus for light volatile oil, comprising a condenser (1) and a valve pipe assembly (3) embedded on the top of the condenser (1). A condensation pipeline (4) is disposed inside the condenser (1), and the valve pipe assembly (3) is arranged close to the condensation pipeline (4). The valve pipe assembly (3) comprises a short connecting pipe (31) embedded on the top of the condenser (1) and located on the inner side of the condensation pipeline (4), a plurality of short connecting guide ports (33) extending from the short connecting pipe (31) towards the condensation pipeline (4), and a valve core (32) movably disposed inside the short connecting pipe (31) and configured to control opening and closing of the plurality of short connecting guide ports (33). The condensation pipeline (4) comprises a condensation pipe (43), the condensation pipe (43) is provided with a plurality of water retaining parts (44), and condensed water can be collected at the condensation pipe (43) by means of the water retaining parts (44), so that a liquid oil-water mixture formed by condensation flows on a water surface in the condensation pipe (43). By avoiding rapid increase in the viscosity of the volatile oil in the oil-water mixture due to an excessively low temperature and reducing the contact between the light volatile oil in the oil-water mixture and the condensation pipe (43), the loss of the light volatile oil adhering to the pipe inner wall of the condensation pipe (43) is reduced, so that the yield of the volatile oil is improved.
A composition having an anti-tumor effect and a use. The composition comprises the following components in parts by weight: 0.1-100 parts of sea cucumber peptides, 0.1-100 parts of albumin peptides, and 0.1-100 parts of wheat oligopeptides. The provided composition has an anti-tumor effect, wherein the sea cucumber peptides can significantly reduce the growth and reproduction speed of tumor cells, can inhibit tumors, can effectively protect the normal function of immune organs, and are safer compared to clinical drugs; the albumin peptide has the effects of remarkably improving mouse cell and humoral immunity, and the wheat oligopeptide is extracted from natural wheat protein, so as to be rich in wheat gluten having wheat protein, which plays an important role in slowing down the reduction of skeletal muscle protein caused by large exercise training loads, etc. The composition can have the effect of inhibiting tumor cell metastasis, and has important theoretical and practical significance for developing anti-tumor products.
Provided are a composition for inhibiting inflammatory responses and promoting angiogenesis and wound healing, and the use thereof. The composition comprises the following components in parts by weight: 0.1-100 parts of a wheat oligopeptide, 0.1-100 parts of a marine fish skin collagen oligopeptide and 0.1-100 parts of a hemoglobin polypeptide. The composition is obtained by means of using the marine fish skin collagen oligopeptide, the wheat oligopeptide and the hemoglobin polypeptide as main ingredients and combining same with a chamomile extract and calcium β-hydroxy-β-methylbutyrate. The effect of promoting wound healing is achieved by means of inhibiting inflammation responses and promoting angiogenesis, wherein multiple aspects of wound healing are taken into account. The composition provides a great practical significance for the development of a product for promoting wound healing.
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
5.
PORIA, CINNAMOMI RAMULUS, ATRACTYLODIS MACROCEPHALAE RHIZOMA AND GLYCYRRHIZAE RADIX ET RHIZOMA DECOCTION EXTRACT AND PREPARATION METHOD THEREFOR
A Poria, Cinnamomi ramulus, Atractylodis macrocephalae rhizome and Glycyrrhizae radix et rhizoma decoction extract and a preparation method therefor. The extract is composed of a Poria, Cinnamomi ramulus, Atractylodis macrocephalae rhizome and Glycyrrhizae radix et rhizoma decoction extract powder and excipients, wherein the excipients are maltodextrin and micropowder silica gel, and the modification ratio of the extract powder, the maltodextrin and the micropowder silica gel is 64-74 : 25-39 : 1. By means of the preparation method, the moisture-proof performance and the direct compression performance of the Poria, Cinnamomi ramulus, Atractylodis macrocephalae rhizome and Glycyrrhizae radix et rhizoma decoction extract powder are improved, and the effect of the subsequent preparation process is improved.
A Farfarae flos and Asteris radix et rhizoma cough-relieving granule composition and a preparation method therefor. The composition comprises the following components: an inclusion complex, an extract powder and a filler comprising lactose and dextrin. The preparation method therefor comprises: extracting Zingiberis rhizoma recens, Asari radix et rhizoma and Magnoliae flos to obtain an volatile oil and medicine residue 1; then performing enzymolysis on Ephedrae herba to obtain an enzymolysis solution and medicine residue 2; decocting Asteris radix et rhizoma, Farfarae flos, Pinelliae rhizoma praeparatum, Xanthii fructus, the medicine residue 1 and the medicine residue 2 with water, combining same with the enzymolysis solution, and then drying same to obtain the extract powder; then performing the inclusion of the volatile oil to obtain the inclusion complex; and finally, mixing the inclusion complex, the extract powder and the filler for granulation to obtain the Farfarae flos and Asteris radix et rhizoma cough-relieving granule composition.
A61K 36/17 - Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Anemarrhenae and is prepared into various conventional pharmaceutical formulations through processes such as pulverization, water decoction and alcohol extraction. The traditional Chinese medicine composition is effective in preventing and treating allergic diseases, hepatitis B and AIDS, elevating leukocytes, preventing and treating radiation injury, reducing toxic and side effects resulting from radiotherapy and chemotherapy, improving the male sexual function, enhancing immunity of the human body and alleviating physical fatigue.
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
Cordyceps sinensis powder and/or 1 to 120 parts by weight of Cordyceps, or is a composition consisting of water and/or alcohol extracts of the above raw materials as active components.
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
Cordyceps sinensis powder, Flos Rosae Rugosae, and Rhizoma Anemarrhenae and is prepared into various conventional pharmaceutical formulations through processes such as pulverization, water decoction and alcohol extraction. The traditional Chinese medicine composition is effective in preventing and treating allergic diseases, hepatitis B and AIDS, elevating leukocytes, preventing and treating radiation injury, reducing toxic and side effects resulting from radiotherapy and chemotherapy, improving the male sexual function, enhancing immunity of the human body and alleviating physical fatigue.
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
Cordyceps sinensis powder and/or 1 to 120 parts by weight of Cordyceps, or is a composition made from water and/or alcohol extracts of the above raw materials as active components. The allergic diseases include allergic rhinitis, allergic dermatitis, urticaria, and/or allergic asthma.
Disclosed is a traditional Chinese medicine combination for regulating immune function and its preparation, wherein the combination is prepared from Chinese medicine including Radix Panacis Quinquefolii, Ganoderma, fermentative cordyceps sinensis powder, Flos Rosae Rugosae, Rhizoma Anemarrhenae, Bulbus Lilii and the like as raw materials by disintegrating, water grilling, alcohol extraction etc. to obtain various clinically acceptable formulations. The combination has the effects of preventing and curing hypersensitivity disease, hepatitis B and AIDS, increasing leucocyte, preventing radiation injury, decreasing the by-effect of chemotherapy and radiotherapy, improving male sexual function, strengthening immunity, and alleviating physical fatigue.
A pharmaceutical composition is made of the following raw materials or water and/or ethanol extract of the following raw materials. The raw materials comprises (in parts by weight): ganoderma lucidum (5-200), American ginseng or ginseng (5-150), and cordyceps fungus powder (1-90) and/or cordyceps (1-120), and further comprises one or more of rosa rugosa thumb (5-90), ganoderma lucidum spore powder (5-150), pseudostellaria heterophylla (10-400), codonopsis pilosula (3-400), and astragalus membranaceus (3-400). The clinical trial indicates that the composition is capable of reducing the HIV viral load in AIDS patients, increasing the number of CD4+ cells and improving the immunity of the patients, has no evident toxic and side effect, and is suitable for long-term use.
The present invention aims to provide a composition for preventing and treating Hepatitis B, and comprises the following raw material in weight proportion: 5-200 portions of ganoderma lucidum, 5-150 portions of radix panacis quinquefolii or radix ginseng, 1-90 portions of fermented cordyceps sinensis powder and/or 1-120 portions of cordyceps, or a composition composed by the water and/or alcohol extract of the raw material as the active ingredient. The invention is used in preparing health care products or medicines for preventing and treating hepatitis B.
A61K 36/39 - Convolvulaceae (Morning-glory family), e.g. bindweed
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A use of a composition in preparing health care products and medicines for preventing and treating allergic diseases. The composition is produced from and comprises the following raw material in weight proportion: 5-200 portions of ganoderma lucidum, 5-150 portions of radix panacis quinquefolii or radix ginseng, 1-90 portions of fermented cordyceps sinensis powder and/or 1-120 portions of cordyceps, or a composition composed by the water and/or alcohol extract of the raw material as the active ingredient. Said allergic diseases include allergic rhinitis, allergic dermatitis, urticaria, and allergic asthma.
An application of a composition for alleviating sexual dysfunction. The composition comprises the following raw materials in parts by weight: 5-200 parts of ganoderma lucidum, 5-150 parts of American ginseng or ginseng, 1-90 parts of cordyceps fungus powder and/or 1-120 parts of cordyceps; or the composition consists of water and/or ethanol extract of the above raw materials as active ingredients.
An application of a composition in preparing a health care product or medicine for preventing and treating leukopenia caused by radiotherapy and chemotherapy. The composition is made of the following raw materials expressed in parts by weight: 5-200 parts of ganoderma lucidum, 5-150 parts of American ginseng or ginseng, 1-90 parts of cordyceps fungus powder and/or 1-120 parts of cordyceps; or the composition consists of water and/or ethanol extract of the above raw materials as active ingredients.
A composition for alleviating toxic and side effect of chemotherapy on malignant tumor patients and an application thereof. The composition contains the following raw materials expressed in parts by weight: 5-200 parts of ganoderma lucidum, 5-150 parts of American ginseng or ginseng, 1-90 parts of cordyceps fungus powder and/or 1-120 parts of cordyceps; or the composition consists of water and/or ethanol extract of the above raw materials as active ingredients.
Cordyceps, and these ingredients are made from Chinese crude drugs or from Chinese crude drug extracts in amounts equivalent to those of the Chinese crude drugs. The composition may further contain 5-90 parts by weight of Flos Rosae Rugosae. The present invention also relates to the use of said composition in the manufacture of prophylactic or therapeutic health foods or medicaments for reducing blood lipids, for resisting oxidation, and for enhancing anoxia endurance. The medicine composition of the present invention can be prepared into any conventional dosage forms by adding any pharmaceutically acceptable auxiliary agents.
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
The present invention aims at providing an application of a peptide of a soft-shell turtle in preparing a medicament for the prevention of a neoplastic disease. The oligopeptide of the soft-shell turtle of the present invention uses the soft-shell turtle as a main ingredient, with small peptides having a distribution of molecular weights of less than 10,000 daltons, where molecular weights ranging between 140 and 1,000 daltons accounts for over 50%.
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
The present invention aims at providing an application of a peptide of a soft-shell turtle in preparing a medicament having a protective feature against radiation hazards. The oligopeptide of the soft-shell turtle of the present invention uses the soft-shell turtle as a main ingredient, with small peptides having a distribution of molecular weights of less than 10,000 daltons, where molecular weights ranging between 140 and 1,000 daltons accounts for over 50%.
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
A61P 39/06 - Free radical scavengers or antioxidants
A61P 17/16 - Emollients or protectives, e.g. against radiation
A traditional Chinese medicine composition for enhancing the human immune function. The traditional Chinese medicine composition consists of 5-150 parts of American ginseng by weight, 5-160 parts of Ganoderma lucidum by weight, 1-90 parts of fermented Cordyceps powder by weight and/or 1-120 parts of Cordyceps sinensis by weight, wherein the sources of raw material are Chinese medicinal materials or Chinese herb extracts, the amount of the latter being equivalent to the amount of the crude version of the above-mentioned Chinese medicinal materials; additionally, 5-90 parts of rose flower by weight can also be added. To the above-mentioned composition is added any pharmaceutically acceptable excipient, and any conventional dosage form including but not limited to tablets, granules, capsules, oral liquids, syrups and pills is prepared using conventional methods of traditional Chinese medicine preparation.
A use of traditional Chinese medicine composition for manufacturing a health food or medicament for preventing and alleviating physical fatigue. The composition, which is prepared by Chinese crude drugs or Chinese herb extracts equivalenting to the amount of crude drugs, consists of Radix Panacis Quinquefolii 5-90 parts by weight, Ganoderma 5-160 parts by weight, fermental Cordyceps Sinensis powder and/or Cordyceps 1-120 parts by weight. The composition also contains Flos Rosae Rugosae 5-90 parts by weight. The present invention also relates to the use of said composition can be used to manufacture a health food or medicament for reducing blood lipid, resisting oxidation and enhancing anoxia endurance. The medicine composition as described can also be added into any pharmaceutically acceptable excipients, and then be prepared into any conventional dosage forms.
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