C25B 9/19 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms
C25B 9/65 - Means for supplying currentElectrode connectionsElectric inter-cell connections
C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
C25B 9/17 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof
2.
COMPOSITIONS AND METHODS FOR RESTORING SUSCEPTIBILITY TO PYRETHROID INSECTICIDES IN RESISTANT POPULATIONS
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (USA)
Inventor
O'Neal, Matthew
Valmorbida, Ivair
Coates, Brad
Arnemann, Jonas
Abstract
Disclosed are double stranded RNA molecules that are toxic to aphids including those that are resistant to pyrethroid insecticides. In particular, interfering RNA molecules capable of interfering with a voltage-gated sodium channel subunit h1 (vgsc-h1) target gene and that are toxic to aphids are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants or as the active ingredient in insecticidal compositions, to confer protection from aphid damage are disclosed.
A01N 57/10 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Reuel, Nigel Forest
Kallmyer, Nathaniel
Abstract
Various embodiments disclosed relate to a sensor assembly probe for determining enzymatic activity. The sensor assembly probe includes an aqueous medium including one or more fluorescent hydrophobic semi-conductive nanoparticles dispersed therein. The assembly further includes an ionic polymer coating at least a portion of a surface of the one or more fluorescent hydrophobic semi-conductive nanoparticles. The assembly further includes a substrate for an enzyme, the substrate disposed between at least two of the one or more fluorescent hydrophobic semi-conductive nanoparticles, the substrate including at least ionic group.
C12Q 1/34 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase
4.
PORCINE SAPOVIRUS ISOLATES AND IMMUNOGENIC COMPOSITIONS THEREFROM
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Zhang, Jianqiang
Tian, Liying
Aljets, Ethan
Abstract
The present disclosure is directed to novel porcine sapoviruses (SaV) isolates, including SaV serially propagated in cell culture, all of which are useful in the preparation of immunogenic compositions and vaccines for treating and preventing disease in swine.
C07K 14/085 - Picornaviridae, e.g. coxsackie virus, echovirus, enterovirus
C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
A61K 31/711 - Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
5.
ESCHERICHIA COLI NHAA MEMBRANE PROTEIN DRUG TARGET AND IMMUNOGENIC COMPOSITIONS THEREFROM
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
HARBIN VETERINARY RESEARCH INSTITUTE (China)
Inventor
Li, Ganwu
Zhang, Haobo
Jiang, Fengwei
Mao, Zhao
Abstract
Escherichia coli nhaAnhaA gene are provided, as are immunogenic compositions therefrom and methods of inducing an immune response against ExPEC in a subject.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Narasimhan, Balaji
Ross, Kathleen A.
Kelly, Sean M.
Mallapragada, Surya K.
Wannemuehler, Michael J.
Abstract
ppp-carboxyphenoxy)hexane (CPH), sebacic anhydride (SA); a SA homopolymer; a CPTEG:CPH copolymer; a CPTEG:SA copolymer; a CPH:SA copolymer; a CPH homopolymer; or a polyester, at least one immunogenic protein of a sarbecovirus; and at least one adjuvant, wherein a first amount of the immunogenic protein and a first amount of the adjuvant are encapsulated within the biodegradable particles, and methods of using the same.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Semrau, Jeremy D.
Dispirito, Alan
Peng, Peng
Abstract
The present disclosure relates to systems and methods for the production of methanobactins. In particular, the disclosure provides modified bacteria and methods of use thereof for production of methanobactin.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Kise, Michio
Johnson, Lee, A.
Zumdome, Lee, E.
Ellerbach, Joseph, J.
Hubner, Cary, S.
Martin, Robert, W.
Morales, Oscar De Jesus
Powell, Levi, John
Hadacek, James, Bailey
Lichtenwalner, Jr., Houstin
Ferren, Bran
Engel, Colin, D.
Abstract
A shield for assembly between a furrow opening disk and a closing system of a planter row unit. The shield includes a front portion adjacent a rear portion, the front and rear portions span between top and bottom edges. A visualization system for a planter row unit having closing system and furrow opening disks. An illumination unit projects an active illumination at an angle onto the trench or furrow formed by the furrow opening disks.
A01B 76/00 - Parts, details or accessories of agricultural machines or implements, not provided for in groups
A01B 15/16 - DiscsScrapers for cleaning discsSharpening attachments
A01B 69/00 - Steering of agricultural machines or implementsGuiding agricultural machines or implements on a desired track
G01B 11/25 - Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures by projecting a pattern, e.g. moiré fringes, on the object
9.
METHODS OF MAKING, PROTECTING, AND DELIVERING STABLE PREBIOTIC COMPOSITIONS
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Curtzwiler, Greg
Lyte, Mark
Abstract
Compositions providing stable and protected prebiotic to provide a prebiotic delivery system to fortify feed, food or water sources for digestion activation of a dopamine precursor are disclosed. The compositions provide a protectant material and a prebiotic dopamine precursor. Methods of making stable protected prebiotic compositions, methods of delivering a fortified feed, food or water source, and methods of treating subjects with the compositions providing stable and protected prebiotics are also disclosed.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Reuel, Nigel Forest
Chan, Yee Jher
Abstract
A variety of applications can include cell-responsive structures to provide enhanced sensitivity of a resonant sensor in cell detection. A cell- responsive layer can be structured over a resonant sensor. The arrangement of the resonant sensor and the cell-responsive layer can be implemented as a resonant sensor to measure changes in cells. With the cell-responsive layer responsive to cells proximate to the cell-responsive layer, changes in resonant frequency of the arrangement of the resonant sensor and the cell-responsive layer over time at which the cells are proximate to the cell-responsive layer can be monitored. Interrogating the resonant sensor can be conducted wirelessly along with wirelessly transmitting data collected from the interrogation. Additional apparatus, systems, and methods are disclosed.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Jiang, Shan
Li, Yifan
Mort, Rebecca Jane
Abstract
An additive for a water-based wood stain includes a polymeric particle including a polymer that includes a repeating unit formed from a compound having the formula X-L1288)alkenyl containing one or more carbon-carbon double bonds, L111010)alkylene interrupted by 0, 1, 2, or 3 heteroatoms chosen from O and NR1wherein R11512020)hydrocarbyl, or substituted or unsubstituted phenyl. The polymeric particle has a particle size in solution of 10 nm to 2000 nm.
C09D 133/00 - Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereofCoating compositions based on derivatives of such polymers
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Cochran, Eric, William
Forrester, Michael, J.
Hohmann, Austin
Hernandez, Nacu
Kuehl, Baker
Williams, Ronald, Christopher
Abstract
The present application is directed to an asphalt pavement product comprising: a reclaimed asphalt pavement product (RAP); and an emulsified product mixed with the RAP, said emulsified product comprising: water; one or more surfactants; one or more stabilizers; one or more polymers; and one or more compounds of formula (I): wherein R and A are as described herein. The present application is also directed to methods of paving a road course using the emulsified product.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Cochran, Eric William
Kraus, George A.
Lee, Ting-Han
Forrester, Michael
Abstract
The present application is directed to a polymer comprising a moiety of formula (I) wherein A, B, X, Y, i, j, s, and k are as described herein and salts thereof and to a process of preparing such a polymer.
C08G 63/189 - Acids containing aromatic rings containing two or more aromatic rings containing condensed aromatic rings containing a naphthalene ring
C08G 63/199 - Acids or hydroxy compounds containing cycloaliphatic rings
C08G 63/685 - Polyesters containing atoms other than carbon, hydrogen, and oxygen containing nitrogen
C08G 69/26 - Polyamides derived from amino carboxylic acids or from polyamines and polycarboxylic acids derived from polyamines and polycarboxylic acids
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Lyte, Mark
Abstract
The present disclosure relates to use of probiotic compositions and/or histamine degrading enzymes for the control of histamine in a farm production animal, companion animal, aquaculture, or a human, to reduce or eliminate the incidence of necrotizing enterocolitis and/or related inflammatory conditions in the gastrointestinal tract or skin, and behavioral conditions. The disclosure also relates to the probiotic compositions and/or histamine degrading enzymes.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Reuel, Nigel Forest
Kallmyer, Nathaniel
Abstract
Various aspects of the instant disclosure relate to a sensor assembly probe for determining enzymatic activity. The sensor assembly probe includes a fluorescent semi-conductive nanoparticle and a solid phase substrate for a predetermined enzyme, the fluorescent semi-conductive nanoparticle adsorbed thereto or at least partially embedded therein.
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
C12Q 1/34 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase
16.
SOFT MAGNETIC WIRE/STRIP ARRAY FOR MOTOR STATOR AND ROTOR
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
UT-BATTELLE, LLC (USA)
Inventor
Cui, Jun
Ouyang, Gaoyuan
Anderson, Iver, E.
Kramer, Matthew
Raminosoa, Tsarafidy
Abstract
A novel, architecture for al motor rotor and stator of an electrical motor device as well as other electromagnetic device using soft magnetic wires and/or strips bundled and shaped to provide a desired magnetic flux path.
H02K 3/04 - Windings characterised by the conductor shape, form or construction, e.g. with bar conductors
H02K 3/02 - Windings characterised by the conductor material
H02K 3/30 - Windings characterised by the insulating material
H02K 15/02 - Processes or apparatus specially adapted for manufacturing, assembling, maintaining or repairing of dynamo-electric machines of stator or rotor bodies
H02K 1/02 - Details of the magnetic circuit characterised by the magnetic material
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Verhoeven, David
Miller, Wyatt Allen
Narasimhan, Balaji
Kimber, Michael
Jones, Douglas
Abstract
This present disclosure provides RNA expression systems based on sequences from plant viruses, insect viruses, and flaviviruses that eliminate the need for expensive modifications. Methods to express and package an RNA polynucleotide without the need for in vitro transcription and lipid nanoparticles are provided. Also provided are methods to package an RNA polynucleotide using synthetic polyanhydride nanoparticles that are stable at room temperature and suitable for delivery by nasal spray.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (USA)
Inventor
Anderson, Iver, E.
White, Emma, Marie Hamilton
Johnson, Duane
Argibay, Nicolas
Kustas, Andrew, B.
Chandross, Michael
Puckett, Raymond, V.
Abstract
Refractory-reinforced multiphase high entropy alloys (RHEAs) advantageously providing high strength and fracture toughness in an as-AM deposited condition and other conditions are described.
C22F 1/04 - Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of aluminium or alloys based thereon
C22F 1/18 - High-melting or refractory metals or alloys based thereon
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Lyte, Mark
Abstract
The present disclosure is directed to dopamine producing probiotics to increase immune responses to vaccination and to provide increased immune protection. The present disclosure is further directed to dopamine producing synbiotic compositions, formulations, plants, and synthetic compounds and their use for targeted clinical and veterinary applications, for example, in promoting health and well-being and enhancing vaccine efficacy. The present disclosure also provides an approach for optimization of synbiotic delivery of a probiotic or other dopamine producing product with a dopamine precursor to beneficially aid in the use of such products for a variety of conditions and diseases, and particularly in the field of vaccines, whether prophylactic or therapeutic.
APPARATUS, SYSTEMS, AND METHODS FOR TUNING THE STRUCTURE, CONDUCTIVITY, AND/OR WETTABILITY OF LASER INDUCED GRAPHENE FOR A VARIETY OF FUNCTIONS INCLUDING MULTIPLEXED OPEN MICROFLUIDIC ENVIRONMENTAL BIOSENSING AND ENERGY STORAGE DEVICES
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Claussen, Jonathan
Chen, Bolin
Gomes, Carmen L.
Abstract
Apparatus, systems, and methods for tuning the structure, conductivity, and/or wettability of laser induced graphene for a variety of functions including but not limited to multiplexed open microfluidic environmental biosensing and energy storage devices. Aspects of this invention introduce a one-step, mask-free process to create, pattern, and tune laser-induced graphene (LIG) with a ubiquitous CO2 laser or other laser. The laser parameters are adjusted to create LIG with different electrical conductivity, surface morphology, and surface wettability without the need for post chemical modification. This can be done with a single lasing. By optionally introducing a second (or third, fourth, or more) lasing(s), the LIG characteristics can be changed in just the same one step of using the laser scribing without other machines or sub-systems. One example is a second lasing with the same laser sub-system at low laser power, wherein the wettability of the LIG can be significantly altered. Such films presented unique superhydrophobicity owing to the combination of the micro/nanotextured structure and the removal of the hydrophilic oxygen-containing functional groups. The ability to tune the wettability of LIG while retaining high electrical conductivity and mechanical robustness allows rational design of LIG based on application.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Tessonnier, Jean-Philippe
Cochran, Eric William
Shanks, Brent Howard
Gansebom, Dustin
Abdolmohammadi, Sanaz
Forrester, Michael J.
Abstract
The present application relates to a polymer comprising a moiety of formula: (I) wherein R, R1, X, n, o, s, m, i, and j are as described herein and salts thereof and to a process of preparing such a polymer.
C08L 67/00 - Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chainCompositions of derivatives of such polymers
C08L 77/06 - Polyamides derived from polyamines and polycarboxylic acids
C08L 33/06 - Homopolymers or copolymers of esters of esters containing only carbon, hydrogen, and oxygen, the oxygen atom being present only as part of the carboxyl radical
C08L 67/02 - Polyesters derived from dicarboxylic acids and dihydroxy compounds
C11D 11/00 - Special methods for preparing compositions containing mixtures of detergents
22.
MEASURING SEED COTTON PROPERTIES USING NEAR INFRARED SENSING
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Wigdahl, Jeffrey, S.
Askey, Jeffrey, C.
Just, John, P.
Abstract
Systems and methods are provided for determining properties of seed cotton based on measurements from a near-infrared (NIR) sensor. The determined properties are indicative of a quality of the seed cotton. The NIR sensor is mounted on harvesting equipment to acquire quality data during harvesting. The quality data may be mapped to field location and/or forwarded on in preparation of further processing.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Cui, Jun
Ott, Ryan, T.
Tang, Wei
Liu, Xubo
Nlebedim, Cajetan, Ikenna
Ouyang, Gaoyuan
Pan, Chaochao
Abstract
A method for fabrication of an anisotropic magnet comprises placing magnet alloy feedstock particles in a deformable metallic container and thermomechanically working the filled container in a manner to elongate the filled container and reduce its cross- sectional area to consolidate the magnet alloy particles to an elongated shape and impart a preferential grain texture to the consolidated, elongated shape. The consolidated, elongated shape is machined to a near-final magnet shape that has a smaller dimension such as magnet length and that includes a metallic tubular skin thereon.
H01F 41/02 - Apparatus or processes specially adapted for manufacturing or assembling magnets, inductances or transformersApparatus or processes specially adapted for manufacturing materials characterised by their magnetic properties for manufacturing cores, coils or magnets
THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (USA)
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
UNIVERSITY OF WASHINGTON (USA)
ALLIANCE FOR SUSTAINABLE ENERGY LLC (USA)
Inventor
Henze, Gregor P.
Smith, Joshua R.
Sarkar, Soumik
Florita, Anthony J.
Jacoby, Margarite
Nezhad, Mohamadtaghi Katanbaf
Saffari, Ali
Tan, Sin Yong
Abstract
An integrated occupancy sensing system includes one or more radio frequency identification (RFID) sensor nodes and one or more base station units. Each of the one or more RFID sensor nodes includes at least one of (1) an image sensor, (2) an acoustic energy sensor, (3) a temperature sensor, (4) an illuminance sensor, or (5) a relative humidity sensor. Each of the one or more base station units is configured to be connected to a power source to emit a continuous wave carrier signal and to receive a reflected signal. Each of the one or more RFID sensor nodes is configured to receive and reflect the continuous wave carrier signal. In response to receiving the reflected signal from the one or more RFID sensor nodes, at least one of the base station units is configured to infer the likelihood of human occupancy in the building.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Cochran, Eric, W.
Hernandez, Nacu
Forrester, Michael, J.
Kuehl, Baker, W.
Hohmann, Austin
Abstract
The present application relates to a thermoplastic graft copolymer including one or more thermoplastic polymers of formula (I): and a branched chain thermoplastic polymer of formula (II): where R1, R2, R3, R4, R4', AETAG, a, b, c, d, and e are as described herein. Also disclosed is the process for preparing the thermoplastic copolymer and its uses.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Cochran, Eric, W.
Williams, R., Chris
Hernandez, Nacu
Hohmann, Austin
Kuehl, Baker, W.
Forrester, Michael, J.
Abstract
The present application relates to a thermoplastic graft copolymer including one or more thermoplastic polymers of formula (I): and a branched chain thermoplastic polymer of formula (II): where R1, R1', R2, R2', R3, R4, R4', AETAG, a, b, c, e, f, g, h, i, and j are as described herein. Also disclosed is the process for preparing the thermoplastic copolymer and its uses.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Mochel, Jonathan P.
Allenspach Jorn, Karin
Gabriel, Vojtech
Zdyrski, Christopher
Abstract
The present invention relates to hepatic organoids and uses thereof. The compositions include models for the study of developmental biology of the liver and other epithelial tissues, drug discovery and toxicity screening, infectious disease biology of various infectious agents, and personalized medicines. Methods for seeding canine intestinal organoids, maintaining an organoid monolayer, and monitoring monolayer integrity are provided. Methods and systems for culturing, freezing, and recovering the frozen organoid cells are also provided. The hepatic organoids may also be used to treat a subject in need, or for identifying a preferred therapeutic agent.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Li, Ganwu
Arruda, Bailey
Shen, Huigang
Zheng, Ying
Abstract
Disclosed herein are methods for detecting and producing PoMV. Further, disclosed herein are immunogenic and/or vaccine compositions and methods for treating or preventing PoMV. The compositions and methods include immunogenic portions of PoMV including entry proteins. In at least particular cases, a mutated version of a portion of the PoMV is utilized, such as a deglycosylated, or amino acid substituted mutant of the spike protein.
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
G01N 33/567 - ImmunoassayBiospecific binding assayMaterials therefor using specific carrier or receptor proteins as ligand binding reagent utilising isolate of tissue or organ as binding agent
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
C12P 21/04 - Cyclic or bridged peptides or polypeptides, e.g. bacitracin
C12N 15/00 - Mutation or genetic engineeringDNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purificationUse of hosts therefor
C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
29.
METAL ORGANIC FRAMEWORKS COMPRISING COPPER IONS AND PROCESSES FOR PREPARING SAME
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
UT-BATTELLE, LLC (USA)
Inventor
Monaco, Steven J.
Lee, Richard J.
Levine, Alan M.
Wistrom, Jonathan Lyle
Peroutka-Bigus, Nathan Drew
Theodore, Merlin
Paranthaman, Mariappan Parans
Bellaire, Bryan Howard
Abstract
Provided is a metal organic framework (MOF) comprising copper ions. Also provided are resin powders, granules or pellets comprising the MOF. In some embodiments, the resin powders, granules or pellets are antimicrobial. Also provided are fibers or sheets comprising the MOF. In some embodiments, the fibers or sheets are antimicrobial. Processes for preparing the MOF are also provided.
C08G 63/68 - Polyesters containing atoms other than carbon, hydrogen, and oxygen
B01J 20/22 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising organic material
C08G 63/91 - Polymers modified by chemical after-treatment
30.
USE OF METHANOBACTIN FOR TREATMENT OF IRON-RELATED DISEASES
HELMHOLTZ ZENTRUM MUENCHEN - DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (Germany)
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (USA)
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Zischka, Hans
Dispirito, Alan Angelo
Semrau, Jeremy David
Abstract
The present invention relates to a methanobactin reducing Fe3+ ions to Fe2+ ions for use in medicine and a pharmaceutical composition comprising said methanobactin as well as to a process for reducing Fe3+ ions to Fe2+ ions ex vivo.
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A61P 7/00 - Drugs for disorders of the blood or the extracellular fluid
31.
BACILLUS SUBTILIS STRAIN WITH STRONG INHIBITION OF ENTEROPATHOGENIC AND FOODBORNE PATHOGENIC BACTERIA
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Mandic Mulec, Ines
Šimunovic, Katarina
Štefanic, Polonca
Erega, Andi
Smole Možina, Sonja
Klancnik, Anja
Zhang, Qijing
Sahin, Orhan
Abstract
Bacillus subtilisCampylobacter jejuniBacillus subtilisBacillus subtilis strain PS-216. The present invention also provides feed or food compositions and probiotic compositions comprising this strain.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Williams, Ronald, Christopher
Cochran, Eric, W.
Huisman, Theodore
Buss, Ashley, F.
Pinto, Irvin
Hernandez, Nacu
Podolsky, Joseph
Forrester, Michael, J.
Staver, Maxwell, D.
Kuehl, Baker, W.
Hohmann, Austin, D.
Abstract
Provided herein are an emulsified asphalt product and an emulsified coating product. Both emulsified products contain one or more rejuvenators of formula (I) or formula (X). The emulsified asphalt product is useful for improving the performance of aged or brittle resinous binders in paving applications while the emulsified coating product is similarly useful in roofing applications. Also provided herein is a treated bituminous pavement where the performance grade varies with depth.
C09D 123/36 - Coating compositions based on homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bondCoating compositions based on derivatives of such polymers modified by chemical after-treatment by reaction with nitrogen-containing compounds, e.g. by nitration
B32B 27/08 - Layered products essentially comprising synthetic resin as the main or only constituent of a layer next to another layer of a specific substance of synthetic resin of a different kind
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Fay, Iii, James E.
Vigil, Dr. Richard Dennis
Soderquist, Dr. John A.
Heller, Andrew S.
Deo, Trung Lo
Lynch, Cameron
Manfre, Danilo R.
Schmittmann, Dr. Beate
Abstract
An entrainment-based filtering system for use in connection with a facemask or respirator that includes: a filter housing defining an interior volume comprising at least one airflow pathway having an airflow pathway length that is longer than the length of the interior volume and spaced within the interior volume; and a plurality of entrainment substrates. The plurality of entrainment substrates is positioned within the at least one airflow pathway and the plurality of substrates and the dimensions of the at least one airflow pathway together function to entrain particles on the surface of the chemically coated entrainment substrates and prevent at least 95% of particles traveling through the at least one airflow pathway from exiting the entrainment-based filter.
IOWA STATE UNIVERSITY RESEARCHFOUNDATION, INC. (USA)
Inventor
Tessonnier, Jean-Philippe
Shanks, Brent, Howard
Cochran, Eric, William
Hadel, Joseph, Eugene
Dell'Anna, Marco, Nazareno
Carter, Prerana
Abstract
The present application relates to a process for preparation of a compound of Formula (I): wherein R1, R2, and R3are as described herein and salts thereof and to a process of preparing such a compound. The present application also relates to a polymer of Formula (V): wherein R3, Y, i, j, s, and m are as described herein and to a process for preparation of such polymers.
C07C 67/08 - Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
C08K 5/12 - EstersEther-esters of cyclic polycarboxylic acids
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Tessonnier, Jean-Philippe
Shanks, Brent, Howard
Cochran, Eric, William
Hadel, Joseph, Eugene
Dell'Anna, Marco, Nazareno
Carter, Prerana
Gansebom, Dustin
Abstract
The present application is directed to processes for the preparation of compounds of Formulae (I), (IV), and (IVb) as described herein. The application further relates to compounds of Formula (IVb) as described herein. Additional embodiments are directed to a processes for the preparation of polymers of Formulae (X), (XVIII), (XIII), and (XIV) as well as to polymers of Formula (XIII) also described herein.
H01F 1/057 - Alloys characterised by their composition containing rare earth metals and magnetic transition metals, e.g. SmCo5 and IIIa elements, e.g. Nd2Fe14B
H01F 1/053 - Alloys characterised by their composition containing rare earth metals
H01F 1/047 - Alloys characterised by their composition
H01F 1/01 - Magnets or magnetic bodies characterised by the magnetic materials thereforSelection of materials for their magnetic properties of inorganic materials
H01F 1/00 - Magnets or magnetic bodies characterised by the magnetic materials thereforSelection of materials for their magnetic properties
37.
MONOTERPENOID AND PHENYLPROPANOID CARBONATE ESTERS AND METHODS OF THEIR MAKING AND USE AS REPELLENTS
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Klimavicz, James
Coats, Joel
Abstract
The present application relates to compounds of formulae (I)-(VII) as defined herein, compositions containing these compounds, methods of their use, and methods of making. The compounds have nematacide activity.
C08G 81/02 - Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers at least one of the polymers being obtained by reactions involving only carbon-to-carbon unsaturated bonds
B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Claussen, Jonathan
Gomes, Carmen, L.
Rainier Alves Soares, Raquel
Hjort, Robert
Cardoso Pola, Cicero
Abstract
Apparatus and methods of fabrication and use of a highly sensitive and label-free laser-induced graphene (LIG) electrode (10) functionalized with biorecognition agents (e.g. antibodies) (18) to electrochemically quantify a target species (e.g. foodborne pathogen Salmonella enterica serovar Typhimurium). In one example, the LIG electrodes are produced by laser induction on polyimide film (12) in ambient conditions, and circumvent need for high-temperature, vacuum environment, and metal seed catalysts commonly associated with graphene-based electrodes fabricated via chemical vapor deposition processes. After functionalization, the LIG biosensors detect a target species across a wide linear range with a low detection limit, and quick response time without need for sample pre-concentration or redox labeling. These LIG immunosensors displayed high selectivity by non-significant response to other bacteria strains, and demonstrate LIG-based electrodes can be used for electrochemical biosensing and immunosensing. One example for rapid, low-cost pathogen detection in food processing facilities before contaminated foods reach the consumer.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Cho, Michael Wan
Abstract
Disclosed herein are immunogenic and/or vaccine compositions and methods for treating or preventing Severe acute respiratory syndrome (SARS). The compositions and methods include an immunogenic portion of the receptor-binding domain (RBD) of the SARS-CoV-2-2 (COVID-19) spike protein. In at least particular cases, a mutated version of a portion of the RBD is utilized, such as a deglycosylated, or amino acid substituted mutant of the spike protein.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Mellata, Melha
Redweik, Graham
Abstract
The present invention relates to probiotic compositions and methods of using such compositions. In particular, the present invention provides method of using segmented filamentous bacteria to improve gastrointestinal health, reduce bacterial pathogens, and stimulate host immune function in poultry.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
NORTHWESTERN UNIVERSITY (USA)
Inventor
Claussen, Jonathan
Parate, Kshama
Hersam, Mark C.
Rangnekar, Sonal V.
Abstract
Methods and systems of fabrication of high resolution, high-throughput electrochemical sensing circuits on a substrate. High resolution electrochemical sensing circuits are printed by an effective additive technique to the substrate. Optionally, post-print annealing converts electrochemically inactive printed graphene into one that is electrochemically active. The printing can be by aerosol jet printing, but is not necessarily limited thereto. An example is inkjet printing and then the post-print annealing. Ink formulation would be adjusted for effectiveness with inkjet printing. Optionally biorecognition agents can be covalently bonded to the printed graphene for the purpose of electrochemical biosensing. High throughput fabrication of high-resolution graphene circuits (feature sizes in the tens of microns < 50 µm) for electrochemical biosensing is possible by chemical functionalization of the graphene surface with a biological agent.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Lyte, Mark
Abstract
The present invention relates to use of probiotic compositions and/or histamine degrading enzymes for the control of histamine in a farm production animal, companion animal, aquaculture, or a human, to reduce or eliminate the incidence of necrotizing enterocolitis and/or related inflammatory conditions in the gastrointestinal tract or skin, and behavioral conditions. The invention also relates to the probiotic compositions and/or histamine degrading enzymes.
G01K 11/00 - Measuring temperature based on physical or chemical changes not covered by group , , , or
G01K 11/32 - Measuring temperature based on physical or chemical changes not covered by group , , , or using changes in transmittance, scattering or luminescence in optical fibres
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Dalal, Vikram
Keogh, David
Abstract
Disclosed are embodiments of a thin-film photovoltaic technology including a single-junction crystalline silicon solar cell with a photonic-plasmonic back-reflector structure for lightweight, flexible energy conversion applications. The back-reflector enables high absorption for long-wavelength and near-infrared photons via diffraction and light-concentration. The thin-film crystalline silicon solar cell is implemented in a heterojunction design with amorphous silicon, where plasma enhanced chemical vapor deposition (PECVD) is used for all device layers, including a low-temperature crystalline silicon deposition step. Excimer laser crystallization is used to integrate crystalline and amorphous silicon within a monolithic process, where a thin layer of amorphous silicon is converted to a crystalline silicon seed layer prior to deposition of a crystalline silicon absorber layer via PECVD. The crystalline nature of the absorber layer and the back-reflector enable efficiencies higher than what is achievable in other thin-film silicon devices.
H01L 31/036 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by their semiconductor bodies characterised by their crystalline structure or particular orientation of the crystalline planes
H01L 31/0232 - Optical elements or arrangements associated with the device
H01L 31/0376 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by their semiconductor bodies characterised by their crystalline structure or particular orientation of the crystalline planes including amorphous semiconductors
H01L 31/0392 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by their semiconductor bodies characterised by their crystalline structure or particular orientation of the crystalline planes including thin films deposited on metallic or insulating substrates
H01L 31/0352 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by their semiconductor bodies characterised by their shape or by the shapes, relative sizes or disposition of the semiconductor regions
H01L 31/18 - Processes or apparatus specially adapted for the manufacture or treatment of these devices or of parts thereof
H01L 31/0445 - PV modules or arrays of single PV cells including thin film solar cells, e.g. single thin film a-Si, CIS or CdTe solar cells
47.
BIOSOLVENTS USEFUL FOR IMPROVED ASPHALT PRODUCTS UTILIZING RECYCLED ASPHALT PAVEMENT OR OTHER BRITTLE ASPHALT BINDERS SUCH AS VACUUM TOWER BOTTOM
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Cochran, Eric, W.
Hernandez, Nacu
Hohmann, Austin
Williams, Ronald, Christopher
Forrester, Michael
Podolsky, Joseph, H.
Ledtje, Paul
Chen, Conglin
Abstract
The present application is directed to an asphalt binder composition comprising: an asphalt binder; a compound of formula (I): wherein R, A, n, and m are as described herein, a compound of formula (II): wherein R', A', n', and m' are as described herein. The present application is also directed to further compositions, methods of producing an asphalt binder composition, and methods of paving.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Carlson, Steven
Day, Tim
Abstract
Methods for preventing feedlot bovine respiratory diseases employing mirtazapine as pre-shipment treatments are disclosed. Compositions are further disclosed. Beneficially, the methods and compositions provide safe and cost-effective management of a costly disease.
THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (Israel)
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Harari, Ally
Soroker, Victoria
Jurenka, Russell
Abstract
The present invention provides pheromone compositions, kits, and formulations, as well as methods for their use in environmentally-friendly methods of pest control.
A01N 37/06 - Unsaturated carboxylic acids or thio-analogues thereofDerivatives thereof
A01N 25/02 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
A01N 35/02 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aliphatically bound aldehyde or keto groups, or thio-analogues thereofDerivatives thereof, e.g. acetals
A01N 65/00 - Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
A01M 1/02 - Stationary means for catching or killing insects with devices attracting the insects
A01M 1/20 - Poisoning, narcotising, or burning insects
C07D 309/06 - Radicals substituted by oxygen atoms
C07F 9/6568 - Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus atoms as the only ring hetero atoms
50.
PORCINE CIRCOVIRUS TYPE 3 (PCV3) VACCINES, AND PRODUCTION AND USES THEREOF
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Iyer, Arun
Hernandez, Luis, Alejandro
Patterson, Abby
Arruda, Bailey
Gimenez-Lirola, Luis, Gabriel
Anstrom, Dave, Michael
Vaughn, Eric, M.
Abstract
The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 3 (PCV3) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV3 infection.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Reuel, Nigel Forest
Carr, Adam Russell
Abstract
Various embodiments relate to a resonator system that can be used to monitor proteins, cells, or small molecules in a container. A resonant sensor, embedded in or on the container, can have an inductive element and a capacitive element, where the container and resonant sensor are structured such that, when a concentration of the proteins, cells, or small molecules in the container changes, dielectric permittivity and conductivity of the proteins, cells, or small molecules contributes to capacitance of the resonant sensor to affect a resonant frequency shift of the resonant sensor. Interrogating the resonant sensor can be conducted wirelessly along with wirelessly transmitting data collected from the interrogation. Additional apparatus, systems, and methods are disclosed.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
METROPOLITAN WATER RECLAMATION DISTRICT OF GREATER CHICAGO LAW DEPARTMENT (USA)
Inventor
Wen, Zhiyou
Peng, Juan
Gross, Martin A.
Kuldip, Kumar
Kunetz, Thomas
Abstract
A system for reducing total dissolved solids in wastewater can include a vertical reactor (10) that can include a flexible sheet material (12), where the flexible sheet material (12) can be configured to facilitate the growth and attachment of an algal biofilm. The vertical reactor (10) can include a shaft (28), where the shaft (28) can be associated with and can support the flexible sheet material (12), and a drive motor (24), where the drive motor (24) can be coupled with the shaft (28) such that the flexible sheet material (12) can be selectively actuated. The system can include a fluid reservoir (30) containing a portion of wastewater (14) through which the flexible sheet material (12) is configured to pass as well as a stressor operably configured to stimulate the algae to produce an extracellular polymeric substance. A method of reducing total dissolved solids in wastewater (14) includes moving an algal biofilm through the wastewater (14) and moving the algal biofilm through a gas (16).
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Lyte, Mark
Villageliu, Daniel Nicholas
Abstract
Enterococcus spp.Enterococcus spp. genomes which are associated with the production of dopamine. The invention also relates to proteins encoded by such nucleic acid molecules as well as nucleic acid markers which are associated with high dopamine production. Moreover, the invention relates to uses of such molecules, including, but not limited to, transforming or transfecting cells or organisms with constructs containing the nucleic acid molecules to create cells or organisms with enhanced dopamine production. The present invention is also directed to kits for identifying bacteria which may be capable of producing dopamine based on the detection of the nucleic acid molecules.
C12N 1/38 - Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factorsStimulation of growth by removal of a chemical compound
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Cochran, Eric, W.
Hernandez, Nacu
Hohmann, Austin
Williams, Ronald, Christopher
Forrester, Michael
Kuehl, Baker
Chen, Conglin
Abstract
The present application is directed to a composition that includes a polymer comprising two or more units of monomer A, with monomer A being a radically polymerizable plant oil, animal oil, synthetic triglyceride, or mixture thereof and an epoxidized vegetable oil, an epoxidized fatty acid, or an epoxidized fatty ester. The present application is also directed to further compositions, methods of producing a liquid cement composition, and methods of paving.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Hudson, Matthew B.
Selsby, Joshua T.
Abstract
This invention relates to extracellular vesicles and method of isolated tissue-specific extracellular vesicles from bodily fluids. The invention further relates to methods of using extracellular vesicles for diagnostic applications for detecting and monitoring diseases, conditions, and damage in a subject. The invention also relates to methods of using extracellular vesicles for therapeutic applications for treating diseases, conditions, and damage in a subject.
C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
C12N 5/077 - Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Wang, Tong
Acevedo, Nuria
Primacella, Monica
Abstract
This invention relates to a method for inhibiting egg yolk gelation resulting from freezing and thawing. This method comprises treating egg yolk with an effective amount of a compound selected from the group consisting of amino acids, hydrolyzed proteins, hydrolyzed carboxymethyl cellulose, polyethylene glycol, and sorbitan esters, to improve the gelation properties of egg yolk. This invention also relates to an egg yolk-containing product having inhibited susceptibility to gelation resulting from freezing comprising the compound selected from the group consisting of amino acids, hydrolyzed proteins, hydrolyzed carboxymethyl cellulose, polyethylene glycol, and sorbitan esters.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Richards, Mark, P.
Hargrove, Mark
Erazo-Castrejon, Sofia
Alagurajan, Jangannathan
Abstract
The disclosure provides for compositions and methods for preparation of meat substitutes containing clover hemoglobin. Even when oxidized, clover hemoglobin retains a red appearance, thereby avoiding common off-color events that plague other meat substitutes, such as those made using soybean hemoglobin.
A23J 1/14 - Obtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from leguminous or other vegetable seedsObtaining protein compositions for foodstuffsBulk opening of eggs and separation of yolks from whites from press-cake or oil-bearing seeds
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Matthiesen, John Edward
Nelson, Jake William
Tessonnier, Jean-Philippe
Cochran, Eric W.
Abdolmohammadi, Sanaz
Hernandez, Nacu
Abstract
The present invention relates to a polymer comprising a repeating group having the structure of formula (I) wherein R, R1, R2, X, i, j, m, n, o, and s are as described herein. The present invention also relates to a process for preparation of such polymers.
C08G 69/26 - Polyamides derived from amino carboxylic acids or from polyamines and polycarboxylic acids derived from polyamines and polycarboxylic acids
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Balema, Viktor
Pecharsky, Vitalij K.
Johnson, Duane
Abstract
Various embodiments disclosed relate to unsaturated polymers that exhibit electrocaloric properties. The polymers can be useful as heat transfer materials in heating and cooling applications.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Lyte, Mark
Villageliu, Daniel Nicholas
Abstract
The present invention is directed to synbiotic compositions of probiotic strains and prebiotics, along with uses thereof for targeted human and animal applications, for example, in promoting health and well-being and/or treating therapeutic conditions. The present invention is also directed to methods of probiotic selection and detection of strains with the ability to produce neurochemicals in the gastrointestinal tract of a subject, providing a microbial endocrinology-based mechanism and approach for optimization of synbiotic delivery of a probiotic with a neurochemical precursor. Still further the present invention is directed to industrial applications for production of dopamine utilizing methods and media suitable for the same.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Sukhoy, Volodymyr
Stoytchev, Alexander
Abstract
Embodiments of the present disclosure describe an efficient O(n log n) method that implements the Inverse Chirp Z-Transform (ICZT). This transform is the inverse of the well-known forward Chirp Z-Transform (CZT), which generalizes the fast Fourier transform (FFT) by allowing the sampling points to fall on a logarithmic spiral contour instead of the unit circle. Thus, the ICZT can be viewed as a generalization of the inverse fast Fourier transform (IFFT).
C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Hernandez, Nacu
Cochran, Eric
Williams, Ronald, Christopher
Forrester, Michael, John
Bradley, William
Kraus, George
Abstract
The present invention relates to a compound of Formula (I): where ℗ R, R1, R2, R3, and Z are as described herein and to a process for preparing a compound of Formula (I). This invention also relates to a process for the synthesis of a polymer which includes providing a monomer composition, providing a compound of Formula (I), and polymerizing monomers within the monomer composition through controlled free radical polymerization with the compound of Formula (I) to form the polymer.
C07D 207/327 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
BRIGHAM YOUNG UNIVERSITY (USA)
Inventor
Claussen, Jonathan
Das, Suprem
Iverson, Brian
Abstract
In a general aspect, an apparatus can include a first carbon nanotube array that is patterned to define a first electrode having a first plurality of electrode segments. The apparatus can also include a second carbon nanotube array that is patterned to define a second electrode having a second plurality of electrode segments. The second plurality of electrode segments can be interdigitated with the first plurality of electrode segments. The apparatus can further include a biorecognition agent disposed on a surface of the first electrode and disposed on a surface of the second electrode. The first plurality of electrode segments can each have a height-to-width aspect ratio of at least 1 to 1.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (USA)
Inventor
Rios, Orlando
Mccall, Scott
Ott, Ryan
Sims, Zachary, Cole
Stromme, Eric, Thomas
Kesler, Michael
Henderson, Hunter, B.
Mcguire, Michael
Abstract
Disclosed herein are embodiments of rapidly solidified alloys that comprise aluminum, a rare earth element, one or more additional alloying elements, such as aluminum, and an optional additive component. The alloy embodiments exhibit a unique microstructure as compared to microstructures obtained from other alloys that are not rapidly cooled. The disclosed aluminum-rare earth element alloys also exhibit improved mechanical properties without the need for post-processing heat treatments and further do not exhibit substantial coarsening.
C22F 1/04 - Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of aluminium or alloys based thereon
C22C 21/06 - Alloys based on aluminium with magnesium as the next major constituent
C22F 1/00 - Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working
C22F 1/047 - Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of aluminium or alloys based thereon of alloys with magnesium as the next major constituent
66.
BONDED PERMANENT MAGNETS PRODUCED BY ADDITIVE MANUFACTURING
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (USA)
Inventor
Ucar, Huseyin
Paranthaman, Mariappan Parans
Rios, Orlando
Monono, Belther Mojoko
Post, Brian K.
Kunc, Vlastimil
Nlebedim, Cajetan I.
Mccallum, R. William
Mccall, Scott K.
Abstract
A method for producing a bonded permanent magnet, comprising: (i) incorporating a solid precursor material comprising a thermoplastic crosslinkable polymer and magnetic particles into an additive manufacturing device, wherein the crosslinkable polymer has a delayed crosslinking ability; (ii) melting the precursor material by heating it to a temperature of at least and no more than 10C above its glass transition temperature; (iii) extruding the melt through the additive manufacturing device and, as the extrudate exits from the nozzle and is deposited on a substrate as a solidified preform of a desired shape, exposing the resultant extrudate to a directional magnetic field of sufficient strength to align the magnetic particles; and (iv) curing the solidified preform by subjecting it to conditions that result in crosslinking of the thermoplastic crosslinkable polymer to convert it to a crosslinked thermoset. The resulting bonded permanent magnet and articles made thereof are also described.
H01F 1/055 - Alloys characterised by their composition containing rare earth metals and magnetic transition metals, e.g. SmCo5
H01F 1/08 - Magnets or magnetic bodies characterised by the magnetic materials thereforSelection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials metals or alloys in the form of particles, e.g. powder pressed, sintered, or bound together
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Verhoeven, David
Trujillo, Jessie Dorothy
Sponseller, Brett
Abstract
The present invention provides vaccine or immunogenic compositions comprising novel antigens derived from the equine strain of influenza H3N8. These proteins and specific immunogenic domains are effective as primary universal influenza antigens. The disclosed vaccines or immunogenic compositions are highly effective in inducing HA specific antibodies reactive to different influenza viruses, mucosal and systemic immune responses, and cross-protection regardless of influenza virus subtypes. In some embodiments, the vaccine is cross-protective against two or more (e.g., 2, 3, 4, 5, or 6) subtypes of influenza with or without the use of an adjuvant.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
MAGNET APPLICATIONS INC. (USA)
Inventor
Li, Ling
Paranthaman, Mariappan Parans
Kunc, Vlastimil
Post, Brian K.
Rios, Orlando
Fredette, Robert H.
Ormerod, John
Nlebedim, Cajetan Ikenna
Lograsso, Thomas
Abstract
A method for producing a bonded permanent magnet by additive manufacturing, comprising: (i)incorporating components of a solid precursor material into at least one deposition head of at least one multi-axis robotic arm of a big area additive manufacturing (BAAM) system, the components of the solid precursor material comprising a thermoplastic polymer and hard magnetic powder; said deposition head performs melting, compounding, and extruding functions; and said BAAM system has an unbounded open-air build space; and (ii) depositing an extrudate of said solid precursor material layer-by-layer from said deposition head until an object constructed of said extrudate is formed, and allowing the extrudate to cool and harden after each deposition, to produce the bonded permanent magnet. The resulting bonded permanent magnet and articles made thereof are also described.
B29C 64/106 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
A23G 1/18 - Apparatus for conditioning chocolate masses for moulding
A23G 1/20 - Apparatus for moulding, cutting, or dispensing chocolate
A23G 1/50 - Cocoa products, e.g. chocolateSubstitutes therefor characterised by shape, structure or physical form, e.g. products with an inedible support
A23G 3/34 - Sweetmeats, confectionery or marzipanProcesses for the preparation thereof
B29C 64/112 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using individual droplets, e.g. from jetting heads
69.
INSECT TOXIN DELIVERY MEDIATED BY A DENSOVIRUS COAT PROTEIN
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (USA)
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Bonning, Bryony C.
Kemmerer, Mariah
Abstract
A coat protein of Junonia coenia densovirus (JcDNV) is used to deliver attached peptide insect toxin across the gut epithelium of a fall armyworm, Spodoptera frugiperda. A fusion protein comprising VP4 attached to an insect toxin via a peptide linker is developed. A composition comprising a JcDNV coat protein attached to an insect toxin via a peptide linker can be used for insect pest control.
C07K 14/005 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from viruses
C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
70.
SURFACE-HARDENED ALUMINUM-RACE EARTH ALLOYS AND METHODS OF MAKING THE SAME
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (USA)
Inventor
Babu, Sudarsanam Suresh
Henderson, Hunter B.
Dehoff, Ryan R.
Plotkowski, Alex J.
Sims, Zachary C.
Rios, Orlando
Ott, Ryan
Sridharan, Niyanth
Weiss, David
Abstract
Embodiments of surface-hardened aluminum-rare earth alloys and methods of making the alloys are disclosed. In some embodiments, the alloy comprises aluminum and 4 wt% to 60 wt% of a rare earth component X having a maximum solid solubility of ≤ 0.5 wt% in aluminum. The surface-hardened alloy component has an alloy bulk portion and a hardened alloy surface portion. At least a portion of the hardened alloy surface portion has a Vickers hardness that is at least 30% greater than a Vickers hardness of the alloy bulk portion.
C22F 1/04 - Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of aluminium or alloys based thereon
C21D 1/10 - Surface hardening by direct application of electrical or wave energySurface hardening by particle radiation by electric induction
71.
ADDITIVE MANUFACTURING METHODS USING ALUMINUM-RARE EARTH ALLOYS AND PRODUCTS MADE USING SUCH METHODS
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Weiss, David
Sims, Zachary, C.
Dehoff, Ryan, R.
Rios, Orlando
Plotkowski, Alex, J.
Babu, Sudarsanam, Suresh
Ott, Ryan
Sridharan, Niyanth
Henderson, Hunter, B.
Abstract
Described herein are additive manufacturing methods and products made using such methods. The alloy compositions described herein are specifically selected for the additive manufacturing methods and provide products that exhibit superior mechanical properties as compared to their cast counterparts. Using the compositions and methods described herein, products that do not exhibit substantial coarsening, such as at elevated temperatures, can be obtained. The products further exhibit uniform microstructures along the print axis, thus contributing to improved strength and performance. Additives also can be used in the alloys described herein.
C22F 1/04 - Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of aluminium or alloys based thereon
72.
OXY-THIO-NITRIDE MIXED NETWORK FORMER SOLID ELECTROLYTES
H01B 5/00 - Non-insulated conductors or conductive bodies characterised by their form
H01B 1/10 - Conductors or conductive bodies characterised by the conductive materialsSelection of materials as conductors mainly consisting of other non-metallic substances sulfides
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Mudring, Anja-Verena
Prodius, Denis
Nlebedim, Cajetan, Ikenna
Abstract
A chemical dissolution method is provided for use in recycling rare earth metal-containing material such as permanent magnet material including end-of-life magnet shapes, magnet scrap and Terfenol-D alloy material by mixing the rare earth metal-containing material and an aqueous solution of a copper (II) salt to dissolve the material in the solution. The dissolved rare earth metal is then precipitated from the aqueous solution as a rare earth metal compound, such as a rare earth metal oxalate or sulfate from which rare earth metal oxide can be obtained.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Coats, Joel, R.
Norris, Edmund, J.
Klimavicz, James, Scott
Abstract
The present invention relates to monoterpenoid and phenylpropanoid containing derivative compounds, methods of making the compounds, compositions comprising the compounds, and methods of repelling pests using the compounds and/or compositions.
A01N 49/00 - Biocides, pest repellants or attractants, or plant growth regulators containing compounds containing the group wherein m+n≥1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group wherein A means a carbon atom or Y, n ≥ 0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof
A01N 43/16 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom six-membered rings with oxygen as the ring hetero atom
A01N 43/40 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
C07C 69/24 - Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with monohydroxylic compounds
C07C 69/74 - Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
A01N 37/06 - Unsaturated carboxylic acids or thio-analogues thereofDerivatives thereof
A01N 37/08 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing carboxylic groups or thio-analogues thereof, directly attached by the carbon atom to a cycloaliphatic ringDerivatives thereof
A01N 37/10 - Aromatic or araliphatic carboxylic acids, or thio-analogues thereofDerivatives thereof
A01N 43/30 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with two or more hetero atoms five-membered rings with two hetero atoms in positions 1,3 with two oxygen atoms in positions 1,3, condensed with a carbocyclic ring
C07D 305/06 - Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring atoms
C07D 305/08 - Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring atoms
C07D 307/68 - Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
C07D 311/16 - Benzo [b] pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
C07D 333/38 - Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C07D 333/24 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
75.
MONOTERPENOID/PHENYLPROPANOID-CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS HERBICIDES
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Coats, Joel, R.
Klimavicz, James, S.
Norris, Edmund, J.
Bessette, Steven, M.
Lindsay, A., David
Abstract
Disclosed are compounds having a monoterpenoid and/or phenylpropanoid moiety and methods of their making and use as pesticidal compounds, such as herbicides.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Coats, Joel, R.
Klimavicz, James, S.
Norris, Edmund, J.
Bessette, Steven, M.
Lindsay, A., David
Abstract
Disclosed are compounds having a monoterpenoid and/or phenylpropanoid moiety and methods of their making and use as pesticidal compounds, such as insecticidal baits.
A01N 25/00 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests
A01N 25/08 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
77.
MONOTERPENOID/PHENYLPROPANOID CONTAINING COMPOUNDS AND METHODS OF THEIR MAKING AND USE AS SEED TREATMENTS
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Coats, Joel, R.
Klimavicz, James, S.
Norris, Edmund, J.
Bessette, Steven, M.
Lindsay, A., David
Abstract
Disclosed are compounds having a monoterpenoid and/or phenylpropanoid moiety and methods of their making and use as pesticidal compounds, such as seed treatments.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Cochran, Eric, W.
Hernandez, Nacu
Forrester, Michael
Abstract
The present invention relates to a homopolymer, copolymer, block copolymer, and statistical copolymer comprising plural polyol monomeric units. The polyol monomeric units being acrylated and acylated or acetalized. The acrylated and acylated or acetalized polyol monomeric units have an average degree of acrylation which is 1 or more, but less than the number of the hydroxyl groups of the polyol and have an average degree of acylation or acetalization which is 1 or more, but less than the number of the hydroxyl groups of the polyol. The present invention also relates to a method of making the homopolymers, copolymers, block copolymers, and statistical copolymers, and using them in various applications, such as asphalt rubber modifiers, adhesives, or an additive in a fracking fluid for oil fracking.
C08F 20/28 - Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety
C08F 220/28 - Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety
C08F 293/00 - Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
B60C 1/00 - Tyres characterised by the chemical composition or the physical arrangement or mixture of the composition
C09J 133/06 - Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
C04B 26/26 - Bituminous materials, e.g. tar, pitch
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Mudring, Anja-Verena
Prodius, Denis
Abstract
A method is provided for separating different rare earth metal oxalates by mixing the different rare earth metal oxalates in an aqueous solution comprising oxalic acid and an organic base so that at least one rare earth metal oxalate is soluble and at least another rare earth metal oxalate is not soluble. The different rare earth metal oxalates that can be separated can include at least one light rare earth metal oxalate and at least one heavy rare earth oxalate, or different heavy rare earth metal oxalates. The separation method can be incorporated as a step in a solvent extraction method that generates rare earth metal oxalates as an intermediate reaction product to simplify extraction processing and lower extraction costs.
THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF AGRICULTURE (USA)
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Huber, Steven C.
Kim, Sang Yeol
Spalding, Martin H.
Wright, David A.
Abstract
An altered RuBisCO activase (RCA) a-isoform lacking redox activity at its carboxy terminus and genetically altered plants that encode an altered RCA α-isoform having an altered DNA at its 3 ' end (or the exon that encodes the redox-sensitive cysteines that are present at the protein's carboxy terminus) so that the encoded RCA α-isoform lacks redox activity at its carboxy terminus are generated. Genetically altered plants that produce the RCA α-isoform lacking redox activity at its carboxy terminus have an increase in at least one agronomic phenotype. Methods of making the genetic alteration in plants and genetically altered plants are described.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Cochran, Eric, W.
Hernandez, Nacu
Forrester, Michael
Hohmann, Austin
Abstract
The present invention relates to a compound having the structure of formula (I), wherein R1, R2, R3, R4, R5, R6, and R7 are as described herein. The present invention also relates to a process for the preparation of a compound of formula (I) and to a process for the synthesis of a polymer using the compound of formula (I) through controlled free radical polymerization.
C07D 207/327 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
IOWA STATE UNIVERSITY RESEARCH FOUNDATON, INC. (USA)
Inventor
Hernandez, Nacu
Cochran, Eric W.
Williams, Ronald Christopher
Hohmann, Austin
Abstract
The present invention relates to a method of preparing a multiblock copolymer. This method comprises i) providing a block copolymer comprising at least one PA block and at least one PB block, where PA represents a polymer block comprising one or more units of monomer A and PB represents a polymer block comprising one or more units of monomer B, with monomers A and B being the same or different, where the block copolymer contains a chain transfer agent moiety (CTA); ii) providing a radically polymerizable monomer C; and iii) polymerizing the block copolymer with monomer C under conditions effective to achieve a number average degree of polymerization (Nn) for the multiblock copolymer of up to 100,000 without gelation. The present invention relates to a multiblock copolymer comprising at least one PA block, at least one PB block, and at least one PC block. PC block is positioned between PA block and PB block, where PC block is a rubber block, and where PA represents a polymer block comprising one or more units of monomer A, PB represents a polymer block comprising one or more units of monomer B, and PC represents a polymer block comprising one or more units of monomer C, with monomers A and B being the same or different.
C08F 293/00 - Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
C09J 153/00 - Adhesives based on block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bondsAdhesives based on derivatives of such polymers
C08L 95/00 - Compositions of bituminous materials, e.g. asphalt, tar or pitch
83.
NEODYMIUM-IRON-BORON MAGNET WITH SELECTIVE SURFACE MODIFICATION, AND METHOD OF PRODUCING SAME
A bulk high performance permanent magnet comprising a neodymium-iron-boron core having an outer surface, and a coercivity-enhancing element residing on at least a portion of said outer surface, with an interior portion of said neodymium-iron-boron core not having said coercivity-enhancing element therein. Also described herein is a method for producing the high-coercivity bulk permanent magnet, the method comprising: (i) depositing a coercivity-enhancing element on at least a portion of an outer surface of a neodymium-iron-boron core substrate to form a coated permanent magnet; and (ii) subjecting the coated permanent magnet to a pulse thermal process that heats said outer surface to a substantially higher temperature than an interior portion of said neodymium-iron-boron core substrate, wherein said substantially higher temperature is at least 200C higher than said interior portion and is of sufficient magnitude to induce diffusion of said coercivity-enhancing element below said outer surface but outside of said interior portion.
B22F 3/16 - Both compacting and sintering in successive or repeated steps
H01F 1/057 - Alloys characterised by their composition containing rare earth metals and magnetic transition metals, e.g. SmCo5 and IIIa elements, e.g. Nd2Fe14B
H01F 41/08 - Winding conductors onto closed formers or cores, e.g. threading conductors through toroidal cores
84.
MEANS AND METHODS FOR TREATING COPPER-RELATED DISEASES
HELMHOLTZ ZENTRUM MÜNCHEN - DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (Germany)
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (USA)
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Zischka, Hans
Lichtmannegger, Josef
Dispirito, Alan, Angelo
Semrau, Jeremy, David
Abstract
The present invention relates to the field of (bio-)medicine, and more particularly to the treatment of copper-related diseases. Novel means and methods for depleting (excess) copper from organs and/or the circulation are provided. Agents with a high copper binding affinity and stabilized forms thereof are provided, as well as a novel treatment regimen. The means and methods of the present invention are particularly useful for treatment of Wilson Disease, but also for treatment of other conditions.
A61K 31/4166 - 1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
85.
MINIATURIZED CONTINUOUS-FLOW FERMENTING APPARATUS, SYSTEMS, AND METHODS
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Attinger, Daniel
Dong, Liang
Chen, Yuncong
Abstract
A system, method, and apparatus for the fermentation of a beverage by use of continuous flow is provided. The fermented beverage can be any of a wine, beer, mead, ale, soda, cider, or other. The invention provides for small-scale fermentation that can be done in a much shorter time than previous batch fermentations. The small-scale and shortened time allows for variables to be introduced and tested to produce new varieties, flavors, qualities, and other combinations that are inputs of the fermented beverage.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
UNIVERSITY OF BONN (Germany)
Inventor
Schnable, Parick, S.
Liu, Sanzhen
Li, Li
Hochholdinger, Frank
Hey, Stefan
Abstract
Disclosed herein is a method for increasing drought tolerance in a plant. The method includes introducing into the plant an expression construct that includes a heterologous promoter operably linked to a polynucleotide that encodes a RTH6 family member. The method can be performed in monocots and dicots. Also, disclosed herein are plants and expression cassettes that include recombinant DNA that contains a heterologous promoter operably linked to polynucleotides that encodes an RTH5 family member.
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Victoria, Joseph Gilbert
Patterson, Abby Rae
Visek, Callie Ann
Iyer, Arun V.
Hobbs, Lea Ann
Arruda, Bailey Lauren
Arruda, Paulo Henrique Elias
Magstadt, Drew Robert
Schwartz, Kent Jay
Abstract
The present invention relates to a vaccine for protecting a piglet against diseases associated with a novel pestivirus. The vaccine commonly includes a pestivirus antigen and, optionally an adjuvant. Methods for protecting pigs against diseases associated with pestivirus, including but not limited to congenital tremors and methods of producing the pestivirus vaccine are also provided.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Thuo, Martin
Cinar, Simge
Tevis, Ian, D.
Abstract
Undercooled liquid metallic core-shell particles, whose core is stable against solidification at ambient conditions, i.e. under near ambient temperature and pressure conditions, are used to join or repair metallic non-particulate components. The undercooled-shell particles in the form of nano-size or micro-size particles comprise an undercooled stable liquid metallic core encapsulated inside an outer shell, which can comprise an oxide or other stabilizer shell typically formed in-situ on the undercooled liquid metallic core. The shell is ruptured to release the liquid phase core material to join or repair a component(s).
B22F 9/24 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using chemical processes with reduction of metal compounds starting from liquid metal compounds, e.g. solutions
B22F 3/105 - Sintering only by using electric current, laser radiation or plasma
B33Y 30/00 - Apparatus for additive manufacturingDetails thereof or accessories therefor
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Kessler, Michael, Richard
Zhang, Chaoqun
Abstract
Vanillin and vanillyl alcohol were modified into methacrylated derivatives. The structures of vanillin-based monomers were characterized by NMR and FTIR. Renewable polymers were prepared from these vanillin-based monomers. The effects of structure and functionality of the vanillin-based monomers on the thermo-mechanical properties of the resulting polymers were investigated and discussed. Polymers from methacrylated vanillyl alcohol (MVA) demonstrated greater storage moduli, higher glass transition temperatures, and thermal resistance than those from methacrylated vanillin (MV) because of the different functionalities of their monomers.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (USA)
UT-BATTELLE, LLC (USA)
ECK INDUSTRIES INCORPORATED (USA)
Inventor
Ludtka, Gerard M.
King, Alex, H.
Rios, Orlando
Mcguire, Michael, A.
Sims, Zachary, C.
Mccall, Scott, K.
Weiss, David
Thorne, Cori
Abstract
A cast alloy includes aluminum and from about 5 to about 30 weight percent of at least one material selected from the group consisting of cerium, lanthanum, and mischmetal. The cast alloy has a strengthening AI11X3 intermetallic phase in an amount in the range of from about 5 to about 30 weight percent, wherein X is at least one of cerium, lanthanum, and mischmetal. The AI11X3 intermetallic phase has a microstructure that includes at least one of lath features and rod morphological features. The morphological features have an average thickness of no more than 700 um and an average spacing of no more than 10 um, the microstructure further comprising an eutectic microconstituent that comprises more than about 10 volume percent of the microstructure.
B22D 7/02 - Casting compound ingots of two or more different metals in the molten state, i.e. integrally cast
B23K 35/22 - Rods, electrodes, materials, or media, for use in soldering, welding, or cutting characterised by the composition or nature of the material
B23P 17/04 - Metal-working operations, not covered by a single other subclass or another group in this subclass characterised by the nature of the material involved or the kind of product independently of its shape
C21D 1/74 - Methods of treatment in inert gas, controlled atmosphere, vacuum or pulverulent material
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
ZOETIS SERVICES LLC (USA)
Inventor
Zhang, Jianqiang
Chen, Qi
Gauger, Phillip
Madson, Darin
Hardham, John Morgan
Bandrick, Meggan
Calvert, Jay Gregory
Thompson, James Richard
Stoeva, Mira Ivanova
Valdez, Walter
Abstract
The present invention is directed to novel nucleotide and amino acid sequences of Porcine Epidemic Diarrhea Virus ("PEDV"), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine PEDV genotypes and isolates. Diagnostic and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention, as are infectious clones useful in the propagation of the virus and in the preparation of vaccines. Particularly important aspects of the invention include polynucleotide constructs that replicate in tissue culture and in host swine. The invention also provides for novel full length PEDV genomes that can replicate efficiently in host animals and tissue culture.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Li, Ling
Wurtele, Eve Syrkin
Abstract
Method of increasing protein content in a eukaryotic cell comprising an NF-YC4 gene comprising modifying the transcriptional repressor binding site; method of producing a plant with increased protein content comprising crossing and selecting for increased protein content; method of increasing resistance to a pathogen or a pest in a plant comprising an NF-YC4 gene comprising modifying the transcriptional repressor binding site, alone or in further combination with expressing QQS in the plant; method for producing a plant with increased resistance to a pathogen or a pest comprising crossing and selecting for increased resistance to the pathogen or the pest; a cell, collection of cells, tissue, organ, or organism in which the NF-YC4 gene comprises a promoter comprising a transcriptional repressor binding site that has been modified so that the transcriptional repressor cannot prevent transcription of the NF-YC4; hybrid plants; and seeds.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Tessonnier, Jean-Philippe
Matthiesen, John Edward
Abstract
Various embodiments disclosed relate to electrocatalytic hydrogenation of muconic acid and polymers formed from the reaction products thereof. In various embodiments, the present invention provides an electrocatalytic method to prepare 3- hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, adipic acid, or a combination thereof, from muconic acid. The method includes passing current through a catalytic cathode in a reactor including an aqueous acidic solution including muconic acid, a supporting electrolyte, and an anode, so as to generate atomic hydrogen on the cathode surface in an amount effective to hydrogenate the muconic acid to yield a product including 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, adipic acid, or a mixture thereof. Also disclosed is the polymerization of 3-hexene-1,6-dioic acid, 2-hexene-1,6-dioic acid, or a combination thereof with another compound, such as a diamine or a dialcohol, to form a polymer, such as a polyamide or a polyester.
Methods and formulations are provided which can be effectively used to improve milk production and decrease the risk of herd culling in postpartum dairy cattle. The inventive formulations comprise a non-steroidal anti-inflammatory drug, such as meloxicam or sodium salicylate. The inventive method comprises administration of the non-steroidal antiinflammatory drug shortly before, during, and/or after parturition. The inventive methods advantageously provide increased whole-lactation milk yield and increased herd retention with only a very short treatment window.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
NORTH CAROLINA STATE UNIVERSITY (USA)
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (USA)
THE CURATORS OF THE UNIVERSITY OF MISSOURI (USA)
Inventor
Wei, Jun-Zhi
Wu, Gusui
Simmons, Carl R.
Baum, Thomas
Davis, Eric Lee
Hussey, Richard
Mitchum, Melissa G.
Abstract
The present invention comprises methods and compositions for controlling nematode parasitism in host plant. The present invention comprises novel polynucleotides and polypeptides encoded by such polynucleotides comprising one or more nucleic acid sequences disclosed herein having a nucleotide sequence comprising any one of SEQ ID NOs: 162-179, a fragment or variant thereof, or a complement or partial complement or substantial complement thereof, or a polypeptide sequence encoded by SEQ ID NOs: 162-179, or a polypeptide sequence that is a fragment or variant of a polypeptide sequence encoded SEQ ID NOs: 162-179.
C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
96.
IMPROVED ASPHALT PRODUCTS AND MATERIALS AND METHODS OF PRODUCING THEM
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
ARCHER DANIELS MIDLAND CO. (USA)
Inventor
Williams, R., Christopher
Podolsky, Joseph, Herbert
Cochran, Eric, W.
Hagberg, Erik
Buss, Ashley, Faye
Abstract
The present invention relates to a method of producing an improved asphalt. The method includes providing an asphalt and providing a non-esterified and non-etherified reaction product of a sorbitol to isosorbide conversion process. The asphalt is mixed with the non-esterified and non-etherified reaction product of a sorbitol to isosorbide conversion process under conditions effective to produce an improved asphalt. Also disclosed are an asphalt product and a method of making an asphalt material.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION INC. (USA)
ARCHER DANIELS MIDLAND CO. (USA)
Inventor
Christopher, Williams, R.
Podolsky, Joseph, Herbert
Cochran, Eric, W.
Hagberg, Erik
Abstract
The present invention relates to a method of producing an improved asphalt. The method involves providing an asphalt and providing a compound of formula (I), as described herein. The asphalt is mixed with the compound of formula (I) under conditions effective to produce an improved asphalt. Also disclosed are an asphalt product and a method of making asphalt material. The invention further discloses a method of producing an improved asphalt comprising providing a polymer modified asphalt and providing a compound of formula (IIa) or formula (II). The polymer modified asphalt is mixed with the compound of formula (Ila) or formula (IIb) under conditions effective to produce an improved asphalt, which is yet another aspect of the present invention.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Ott, Ryan, T.
Mccallum, Ralph, W.
Jones, Lawrence, L.
Abstract
A method of treating rare earth metal-bearing permanent magnet scrap, waste or other material in a manner to recover the heavy rare earth metal content separately from the light rare earth metal content. The heavy rare earth metal content can be recovered either as a heavy rare earth metal-enriched iron based alloy or as a heavy rare earth metal based alloy.
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (USA)
Inventor
Cochran, Eric, W.
Williams, R., Christopher
Hernandez, Nacu
Ferreira Peralta, Elvira, Joana
Forrester, Michael, John
Abstract
The present invention relates to a thermoplastic copolymer, block copolymer, and statistical copolymer comprising plural acrylated polyol monomeric units having different degrees of acrylation of hydroxyl groups. The acrylated polyol monomeric units have an average degree of acrylation greater than 1 and less than the number of the hydroxyl groups of the polyol. The present invention also relates to a method of making the thermoplastic copolymer, block copolymer, and statistical copolymer, and using them in various applications, such as asphalt rubber modifiers, adhesives, or an additive in a tracking fluid for oil tracking.