Systems, devices, and techniques are disclosed for differentiating a therapeutic dose and a priming event to properly administer medication to patients. In one example aspect, a method for differentiating therapeutic doses and priming events in administering a medication to a patient includes determining a time window for monitoring dispensing of the medication by an injection pen device. Multiple dispense events each releasing an amount of the medication occur in the time window. The method also includes classifying dispense events prior to a last dispense event in the time window as priming events or therapeutic doses and designating the last dispense event in the time window as a therapeutic dose for facilitating calculation and tracking of a dosage amount for the patient.
G16H 20/13 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers
2.
OVERTAPE DESIGNS FOR DEVICES SUCH AS GLUCOSE SENSORS
Embodiments of the invention provide skin adhesive patches designed to ease a diabetic patient's maneuverability and alignment of a glucose sensing device as the patient adheres the device to their skin. Embodiments of the invention can be adapted for use with a wide variety of medical components that are coupled to the skin of patients, including insulin infusion sets, patch pumps, and all-in-one patch sets.
Fluid reservoir systems are disclosed herein. According to some embodiments, the present technology includes a reservoir defining a cavity and a plunger slidably received within the cavity. The plunger includes a vial interface, a plunger rod extending distally from the vial interface, and a needle extending longitudinally through the plunger rod. The needle has an inlet end at the vial interface and an outlet end proximate a distal portion of the plunger rod. When an outlet end of a vial of fluid medication is coupled to the vial interface, the needle extends through a septum of the vial such that the inlet end of the needle is disposed within the vial. When the plunger is fluidly coupled to the vial, proximal movement of the plunger and vial relative to the reservoir draws the fluid medication out of the vial, through the needle, and into the interior region of the reservoir.
Filters for use with fluid infusion devices are disclosed herein. According to some embodiments, the present technology includes a system for delivering a fluid medication to a patient at an infusion site, the system comprising a fluid conduit configured to transport a fluid medication along at least a portion of a fluid path extending between a reservoir containing the fluid medication and a cannula subcutaneously inserted in a patient at an infusion site, and a filter disposed within the fluid conduit and configured to trap particulates that form in the fluid medication, wherein the filter comprises a porous structure including glycerin.
Techniques related to temporary setpoint values are disclosed. The techniques may involve causing operation of a fluid delivery device in a closed-loop mode for automatically delivering fluid based on a difference between a first setpoint value and an analyte concentration value during operation of the fluid delivery device in the closed-loop mode. Additionally, the techniques may involve obtaining a second setpoint value. The second setpoint value may be a temporary setpoint value to be used for a period of time to regulate fluid delivery, and the second setpoint value may be greater than the first setpoint value. The techniques may further involve causing operation of the fluid delivery device for automatically reducing fluid delivery for the period of time based on the second setpoint value.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16Z 99/00 - Subject matter not provided for in other main groups of this subclass
Medical apparatus for use in monitoring and treatment of diabetes, comprised of infusion pumps, programmers, glucose monitors, glucose strip meters, and programming software and software algorithms sold as an integral component for use in operating such apparatus.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Downloadable mobile application software for mobile devices used to display, manage, monitor, and track blood glucose and insulin for use in diabetes; downloadable and recorded computer software used to operate and manage diabetes and blood glucose medical devices. Devices for monitoring blood glucose for medical purposes; insulin pumps; insulin injectors; insulin pens consisting of insulin injectors, blood glucose sensors, and insulin monitors; medical apparatuses, namely, insulin delivery systems comprised of glucose monitors, insulin monitors, infusion sets, and infusion reservoirs sold as a unit and used to display, manage, monitor, and track blood glucose and insulin for use in diabetes patient management.
09 - Scientific and electric apparatus and instruments
Goods & Services
Downloadable and mobile applications used to measure, collect, transmit, monitor, track and analyze diabetes information and diabetes patient data; downloadable and mobile applications used to operate, monitor and manage diabetes medical devices, insulin pumps and glucose monitors; downloadable and mobile applications used for the monitoring and treatment of diabetes; downloadable computer application software for mobile devices, namely, software for accessing a diabetes patient's medical and physiological data.
9.
INFUSION DEVICES AND RELATED METHODS AND SYSTEMS FOR PREEMPTIVE ALERTING
Techniques disclosed herein relate to infusion devices and alerts. In some embodiments, the techniques may involve determining an expected glucose measurement value after delivery of a correction bolus based on an amount of the correction bolus and a current amount of active insulin in a body of a patient. The techniques may further involve obtaining a current glucose measurement value. The techniques may further involve detecting an anomalous response to the correction bolus responsive to determining that a difference between the current glucose measurement value and the expected glucose measurement value exceeds a predetermined threshold.
A61M 5/168 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Downloadable and recorded computer software and downloadable
mobile applications used to measure, collect, transmit,
monitor, track and analyze diabetes information and patient
data; downloadable and recorded computer software and
downloadable mobile applications used to operate, monitor
and manage medical devices, insulin pumps and glucose
monitors; downloadable and recorded computer software and
downloadable mobile applications used for the monitoring and
treatment of diabetes; computer hardware and peripherals for
use in the medical field; downloadable electronic
publications in the nature of books, manuals, articles,
newsletters and brochures in the field of detection,
monitoring and treatment of diabetes and the use of medical
devices used to detect, monitor and treat diabetes. Medical devices used for the treatment of diabetes; medical
apparatus for diabetes, namely, blood glucose monitors;
medical equipment, namely, instruments and sensors for
measuring blood glucose levels and instruments and sensors
for diabetes monitoring; infusion apparatus for therapeutic
purposes; injection device for pharmaceuticals; medical test
kits for diabetes monitoring for home use. Providing courses of instruction in the field of detection,
monitoring and treatment of diabetes and the use of medical
devices used to detect, monitor and treat diabetes;
providing online non-downloadable electronic publications in
the nature of books, manuals, articles, newsletters and
brochures in the field of detection, monitoring and
treatment of diabetes and the use of medical devices used to
detect, monitor and treat diabetes. Providing temporary use of non-downloadable computer
software used for the detection, monitoring, management, and
treatment of diabetes; providing temporary use of
non-downloadable computer software used to operate, monitor
and manage medical devices, insulin pumps and glucose
monitors. Providing medical information; providing medical information
via a website; providing medical information in the field of
detection, monitoring and treatment of diabetes and the use
of medical devices used to detect, monitor and treat
diabetes.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Downloadable and recorded computer software and downloadable
mobile applications used to measure, collect, transmit,
monitor, track and analyze diabetes information and patient
data; downloadable and recorded computer software and
downloadable mobile applications used to operate, monitor
and manage medical devices, insulin pumps and glucose
monitors; downloadable and recorded computer software and
downloadable mobile applications used for the monitoring and
treatment of diabetes; computer hardware and peripherals for
use in the medical field; downloadable electronic
publications in the nature of books, manuals, articles,
newsletters and brochures in the field of detection,
monitoring and treatment of diabetes and the use of medical
devices used to detect, monitor and treat diabetes. Medical devices used for the treatment of diabetes; medical
apparatus for diabetes, namely, blood glucose monitors;
medical equipment, namely, instruments and sensors for
measuring blood glucose levels and instruments and sensors
for diabetes monitoring; infusion apparatus for therapeutic
purposes; injection device for pharmaceuticals; medical test
kits for diabetes monitoring for home use. Providing courses of instruction in the field of detection,
monitoring and treatment of diabetes and the use of medical
devices used to detect, monitor and treat diabetes;
providing online non-downloadable electronic publications in
the nature of books, manuals, articles, newsletters and
brochures in the field of detection, monitoring and
treatment of diabetes and the use of medical devices used to
detect, monitor and treat diabetes. Providing temporary use of non-downloadable computer
software used for the detection, monitoring, management, and
treatment of diabetes; providing temporary use of
non-downloadable computer software used to operate, monitor
and manage medical devices, insulin pumps and glucose
monitors. Providing medical information; providing medical information
via a website; providing medical information in the field of
detection, monitoring and treatment of diabetes and the use
of medical devices used to detect, monitor and treat
diabetes.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Downloadable and recorded computer software and downloadable
mobile applications used to measure, collect, transmit,
monitor, track and analyze diabetes information and patient
data; downloadable and recorded computer software and
downloadable mobile applications used to operate, monitor
and manage medical devices, insulin pumps and glucose
monitors; downloadable and recorded computer software and
downloadable mobile applications used for the monitoring and
treatment of diabetes; computer hardware and peripherals for
use in the medical field; downloadable electronic
publications in the nature of books, manuals, articles,
newsletters and brochures in the field of detection,
monitoring and treatment of diabetes and the use of medical
devices used to detect, monitor and treat diabetes. Medical devices used for the treatment of diabetes; medical
apparatus for diabetes, namely, blood glucose monitors;
medical equipment, namely, instruments and sensors for
measuring blood glucose levels and instruments and sensors
for diabetes monitoring; infusion apparatus for therapeutic
purposes; injection device for pharmaceuticals; medical test
kits for diabetes monitoring for home use. Providing courses of instruction in the field of detection,
monitoring and treatment of diabetes and the use of medical
devices used to detect, monitor and treat diabetes;
providing online non-downloadable electronic publications in
the nature of books, manuals, articles, newsletters and
brochures in the field of detection, monitoring and
treatment of diabetes and the use of medical devices used to
detect, monitor and treat diabetes. Providing temporary use of non-downloadable computer
software used for the detection, monitoring, management, and
treatment of diabetes; providing temporary use of
non-downloadable computer software used to operate, monitor
and manage medical devices, insulin pumps and glucose
monitors. Providing medical information; providing medical information
via a website; providing medical information in the field of
detection, monitoring and treatment of diabetes and the use
of medical devices used to detect, monitor and treat
diabetes.
Disclosed herein are techniques related to dynamic forecasts. The techniques may involve obtaining, from a medical device, measurement data for a patient; forecasting a plurality of values for a condition of the patient based on a forecasting model and the obtained measurement data; providing a graphical user interface depicting the plurality of forecasted values and comprising a plurality of adjustable graphical user interface elements, each associated with a time period and an activity or event likely to influence the condition; obtaining an adjustment to a first adjustable graphical user interface element; in response to obtaining the adjustment to the first adjustable graphical user interface element, updating at least one of the forecasted values based on the adjustment to the first adjustable graphical user interface element, the obtained measurement data, and the forecasting model; and dynamically updating the graphical user interface to reflect the updated at least one forecasted value.
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
In general, the disclosure describes techniques for generating sounds in fully sealed medical devices. The example techniques for generating sounds in medical devices include the use of a plurality of sound chambers arranged in a stacked configuration that propagate the sound, along with one or more diaphragms configured to vibrate in response to the sound propagating through the medical device. In one or more examples, an external housing that includes an overlay cover may fully enclose the medical device, where the overlay cover (e.g., the entire overlay cover or a part of the overlay cover) also vibrates to propagate the sound out of the medical device.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Downloadable mobile application software for mobile devices used to display, manage, monitor, and track blood glucose and insulin for use in diabetes Devices for monitoring blood glucose for medical purposes; insulin pumps; insulin injectors; insulin pens consisting of insulin injectors, blood glucose sensors, and insulin monitors; medical apparatuses, namely, insulin delivery systems comprised of glucose monitors, insulin monitors, infusion sets, and infusion reservoirs sold as a unit and used to display, manage, monitor, and track blood glucose and insulin for use in diabetes patient management
16.
SYNERGISTIC FEATURES AND FUNCTIONS RELATED TO OPERATION OF A MEDICATION DELIVERY SYSTEM AND A MEAL TRANSACTION APPLICATION
The subject matter of this disclosure generally relates to a medical device system and related methodologies that leverage data associated with the use of a meal transaction application, such as an application for ordering food delivery. Data generated by the meal transaction application can be leveraged by a patient care system or application for purposes of diet or calorie logging. Alternatively or additionally, the meal transaction data can be leveraged for purposes of controlling the administration of therapy by a medication delivery system, such as an insulin infusion pump.
medical apparatus for use in monitoring and treatment of diabetes, comprised of infusion pumps, programmers, glucose monitors, glucose strip meters, and programming software and software algorithms sold as an integral component for use in operating such apparatus
18.
ENERGY MANAGEMENT BASED ON AN OPEN SWITCH CONFIGURATION
A sensor assembly for sensing a physiological characteristic includes a housing, and a power source and a power control switch within the housing. The power control switch is electrically coupled to the power source, and is configured to inhibit delivery of power to one or more components of the sensor assembly when the sensor assembly is in a pre-deployment state, and maintain the delivery of power to the one or more components of the sensor assembly when the sensor assembly is in a deployed state. In some examples, an output of the power control switch is latched by a power latch upon deployment of the sensor assembly.
A glucose biosensor encasement includes a first membrane and a second membrane. The first membrane has a first interlocking segment. The second membrane has a second interlocking segment cooperating with the first interlocking segment of the first membrane to provide a cavity between the first membrane and the second membrane configured to receive a glucose sensor. At least one of the first membrane and the second membrane comprises a semi-permeable portion configured to regulate diffusion characteristics of glucose through the membrane to realize a sensitivity for a sensor in the cavity. A method is also provided.
A system for reducing sensor variability includes a sensor configured to generate real-time data relating to glucose sensitivity. The system causes performance of accessing the real-time data from the sensor relating to glucose sensitivity and inputting the real-time data into a machine learning model. The system also causes performance of estimating by the machine learning model an expected glucose sensitivity based on the real-time data and correcting the glucose sensitivity based on the expected glucose sensitivity.
Disclosed herein are techniques related to determining medical parameters. In some embodiments, the techniques involve: obtaining a metric of insulin dosage for a patient; and determining at least one carbohydrate-to-insulin ratio for the patient based at least in part on a model and using the obtained metric of insulin dosage for the patient, wherein parameters of the model were determined based on data associated with a population of patients.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
Embodiments of the invention provide compositions useful in implantable devices such as analyte sensors as well as methods for making and using such compositions and devices. In typical embodiments of the invention, the device is a glucose sensor comprising a polymeric composition disposed on a flexible assembly within the sensor that includes amounts of one or more immunosuppressant agents designed to provide such sensors with improved material properties such as enhanced biocompatibility.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
23.
DIABETES THERAPY BASED ON DETERMINATION OF FOOD ITEM
Techniques for therapy delivery for diabetes treatment are provided. In some embodiments, the techniques may involve identifying an object as a food item based on a representation of the object. In some embodiments, the techniques may involve generating nutrition information or volume information of the food item. The techniques may involve determining that the nutrition information or the volume information of the food item exceeds a threshold. The techniques may involve determining that the patient's glucose level will rise based on the determination the nutrition information or the volume information of the particular food item exceeds the threshold. The techniques may involve generating therapy information for a patient based on the determination that the patient's glucose level will rise. The techniques may involve automatically administering insulin to the patient to cause the glucose level of the patient to lower to within a predetermined range and based on the therapy information.
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Downloadable and recorded computer software and downloadable mobile applications used to measure, collect, transmit, monitor, track and analyze diabetes information and patient data; downloadable and recorded computer software and downloadable mobile applications used to operate, monitor and manage medical devices, insulin pumps and glucose monitors; downloadable and recorded computer software and downloadable mobile applications used for the monitoring and treatment of diabetes; computer hardware and peripherals for use in the medical field; downloadable electronic publications in the nature of books, manuals, articles, newsletters and brochures in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes.
(2) Medical devices used for the treatment of diabetes; medical apparatus for diabetes, namely, blood glucose monitors; medical equipment, namely, instruments and sensors for measuring blood glucose levels and instruments and sensors for diabetes monitoring; infusion apparatus for therapeutic purposes; injection device for pharmaceuticals; medical test kits for diabetes monitoring for home use. (1) Providing courses of instruction in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes; providing online non-downloadable electronic publications in the nature of books, manuals, articles, newsletters and brochures in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes.
(2) Providing temporary use of non-downloadable computer software used for the detection, monitoring, management, and treatment of diabetes; providing temporary use of non-downloadable computer software used to operate, monitor and manage medical devices, insulin pumps and glucose monitors.
(3) Providing medical information; providing medical information via a website; providing medical information in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Downloadable and recorded computer software and downloadable mobile applications used to measure, collect, transmit, monitor, track and analyze diabetes information and patient data; downloadable and recorded computer software and downloadable mobile applications used to operate, monitor and manage medical devices, insulin pumps and glucose monitors; downloadable and recorded computer software and downloadable mobile applications used for the monitoring and treatment of diabetes; computer hardware and peripherals for use in the medical field; downloadable electronic publications in the nature of books, manuals, articles, newsletters and brochures in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes.
(2) Medical devices used for the treatment of diabetes; medical apparatus for diabetes, namely, blood glucose monitors; medical equipment, namely, instruments and sensors for measuring blood glucose levels and instruments and sensors for diabetes monitoring; infusion apparatus for therapeutic purposes; injection device for pharmaceuticals; medical test kits for diabetes monitoring for home use. (1) Providing courses of instruction in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes; providing online non-downloadable electronic publications in the nature of books, manuals, articles, newsletters and brochures in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes.
(2) Providing temporary use of non-downloadable computer software used for the detection, monitoring, management, and treatment of diabetes; providing temporary use of non-downloadable computer software used to operate, monitor and manage medical devices, insulin pumps and glucose monitors.
(3) Providing medical information; providing medical information via a website; providing medical information in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Downloadable and recorded computer software and downloadable mobile applications used to measure, collect, transmit, monitor, track and analyze diabetes information and patient data; downloadable and recorded computer software and downloadable mobile applications used to operate, monitor and manage medical devices, insulin pumps and glucose monitors; downloadable and recorded computer software and downloadable mobile applications used for the monitoring and treatment of diabetes; computer hardware and peripherals for use in the medical field; downloadable electronic publications in the nature of books, manuals, articles, newsletters and brochures in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes.
(2) Medical devices used for the treatment of diabetes; medical apparatus for diabetes, namely, blood glucose monitors; medical equipment, namely, instruments and sensors for measuring blood glucose levels and instruments and sensors for diabetes monitoring; infusion apparatus for therapeutic purposes; injection device for pharmaceuticals; medical test kits for diabetes monitoring for home use. (1) Providing courses of instruction in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes; providing online non-downloadable electronic publications in the nature of books, manuals, articles, newsletters and brochures in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes.
(2) Providing temporary use of non-downloadable computer software used for the detection, monitoring, management, and treatment of diabetes; providing temporary use of non-downloadable computer software used to operate, monitor and manage medical devices, insulin pumps and glucose monitors.
(3) Providing medical information; providing medical information via a website; providing medical information in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes.
27.
SYSTEMS AND METHODS FOR IMPEDIMETRIC GLUCOSE SENSING USING BORONIC ACID VIOLOGEN (OBBV)
An oxygen-independent analyte sensor includes at least one electrode and an oxygen-independent analyte sensing molecule disposed on the at least one electrode. The oxygen-independent analyte sensing molecule is electrografted on to the at least one electrode. The sensor may process an electrochemical impedance spectroscopy (EIS) parameter value in response to exposure to an analyte.
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
Techniques disclosed herein relate to glucose level measurement and/or management. In some embodiments, the techniques involve obtaining in vivo characteristics of a glucose sensor predicted using fabrication process measurement data associated with the glucose sensor, the in vivo characteristics including an in vivo sensitivity, an in vivo intercept, or a combination thereof; receiving sensor measurement data measured by the glucose sensor, the sensor measurement data including sensor current (Isig), counter voltage (Vcntr), electrochemical impedance spectroscopy (EIS) data, an age of the glucose sensor, or a combination thereof; and estimating a sensor glucose (SG) value using an SG model, wherein input parameters of the SG model include the in vivo characteristics of the glucose sensor and the sensor measurement data, and the SG value is an output of the SG model.
A medicine administration and tracking system includes a delivery device configured to deliver a plurality of doses of medicine over a plurality of days and a computing device configured to receive dose information for each dose. The computing device includes a software application operable to cause the computing device to retrieve the dose information for all doses within a pre-determined period of days, categorize each dose within the pre-determined period of days into one of a plurality of time blocks throughout a 24-hour timeframe, determine a time of interest based on a time block of the plurality of time blocks having the least amount of doses categorized therein, and select a physiological parameter reading from a plurality of physiological parameter readings as a physiological parameter reading of interest based on a proximity of a time of the physiological parameter reading to the determined time of interest.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
A processor-implemented method includes receiving sensor measurement data from a glucose sensor; selecting, based on the sensor measurement data, a first regional sensor glucose (SG) model from a first plurality of regional SG models for respective regions of a first plurality of regions of an input parameter space associated with the sensor measurement data, and a second regional SG model from a second plurality of regional SG models for respective regions of a second plurality of regions of the input parameter space; estimating a first SG value and a second SG value using the first regional SG model and the second regional SG model, respectively; and determining a predicted SG value based on a combination of the first SG value and the second SG value. The input parameter space is partitioned into the first plurality of regions and the second plurality of regions using different partition schemes.
Techniques disclosed herein relate to automatic association of a non-medical device with a medical device. In some embodiments, the techniques involve pre-storing first identification information of a first device in a second device, receiving second identification information of the first device by the second device from the first device, and establishing a secure communication link between the first device and the second device based on determining by the second device that the second identification information corresponds to the first identification information. At least one of the first device or the second device includes a medical device.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
H04L 67/10 - Protocols in which an application is distributed across nodes in the network
H04W 12/03 - Protecting confidentiality, e.g. by encryption
H04W 12/04 - Key management, e.g. using generic bootstrapping architecture [GBA]
An analyte sensor includes a microcontroller, a base layer, a conductive layer disposed on the base layer where the conductive layer includes a working electrode configured to provide a current signal in presence of glucose, an interference rejection membrane (“IRM”) layer disposed on the working electrode where the IRM layer is negatively charged, and an enzyme layer disposed on the IRM layer where the enzyme layer includes an enzyme selected to generate a detectable electrical signal upon exposure to the glucose. The microcontroller is configured to process an electrochemical impedance spectroscopy (EIS) parameter to determine a state of the IRM layer.
Infusion devices are disclosed herein. The present technology includes, for example, an infusion device for delivering a medicament to a body of a user. The device can comprise an insertion assembly comprising a cannula, a reservoir assembly comprising a reservoir configured to receive a medicament, and a trigger assembly configured to trigger insertion of the cannula into the user in response to a command from a remote computing device communicatively coupled to the infusion device.
A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
35.
NUTRITIONAL CONTENT DETERMINATION BASED ON GESTURE DETECTION DATA
Techniques disclosed herein relate to nutritional content determination based on gesture detection data. In some examples, the techniques involve obtaining gesture detection data corresponding to consumption of a food item or a drink, determining nutritional content of the food item or the drink based on the gesture detection data, and causing delivery of insulin in accordance with the nutritional content of the food item or the drink.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
H04W 4/80 - Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
36.
CONTEXTUAL PERSONALIZED CLOSED-LOOP ADJUSTMENT METHODS AND SYSTEMS
Techniques for adjustment of control parameters are provided. In some embodiments, the techniques may involve causing fluid delivery to a patient based on a first value for a control parameter. The techniques may further involve determining an anomalous physiological condition of the patient. The techniques may further involve in response to determining the anomalous physiological condition, causing fluid delivery to the patient based on a second value for the control parameter.
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
A medical device includes a sensor to observe a characteristic of an anatomy, and a sensor base coupled to the sensor. The medical device includes a coupling system to couple the sensor base to the anatomy. The coupling system includes a first adhesive member and a second adhesive member. The first adhesive member is coupled to the sensor base and the second adhesive member is to couple to the anatomy. The second adhesive member includes at least one cut-out to direct moisture to an ambient environment surrounding the medical device.
This invention pertains to systems and components useful for infusing medications such as insulin. Typically, the components are used to deliver insulin to a diabetic patient at a site of infusion over a period of time greater than 4 days. The system components typically comprise a cannula adapted for subcutaneous insertion into a diabetic patient. The system further comprises a fluid conduit adapted to deliver the insulin solution from a medication reservoir to the site of infusion and a depot in operable contact with the fluid conduit. The depot comprises selected materials including a site-loss mitigating agent (such as heparin) which inhibits inflammation at the site of infusion, and encapsulation of the cannula at the site of infusion. The site-loss mitigating agent is not premixed with the insulin, and instead is adapted to contact the insulin solution in the depot as the insulin solution flows from the medication reservoir to the site of infusion.
A61M 5/38 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests with means for eliminating or preventing injection or infusion of air into body using hydrophilic or hydrophobic filters
An insertion set system includes a base configured to be secured to a patient, and a flexible tubing on the base. The flexible tubing has a distal end portion forming a cannula to be inserted into the patient. An inserter having a needle is received by the base. The needle has a channel in which the distal end portion of the flexible tubing is received. The needle is able to slide relative to the flexible tubing, to selectively withdraw the needle off of the distal end portion of the flexible tubing. The base may include a passage for fluid flow arranged transverse to the axial dimension of the distal end portion of the flexible tubing.
Techniques for monitoring a physiological condition of a patient are provided. In some embodiments, the techniques may involve obtaining a predictive association model associated with the patient, wherein the predictive association model comprises an association of two or more categorical state values that are predictive of the patient consuming a meal. The techniques may further involve obtaining real-time data associated with the patient. The techniques may further involve determining a current state of the patient based at least in part on the real-time data by transforming the real-time data into two or more current state categorical values. The techniques may further involve predicting consumption of a meal in response to determining the two or more current state categorical values match the two or more categorical state values of the association.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
09 - Scientific and electric apparatus and instruments
Goods & Services
Downloadable and mobile applications used to measure, collect, transmit, monitor, track and analyze diabetes information and diabetes patient data; downloadable and mobile applications used to operate, monitor and manage diabetes medical devices, insulin pumps and glucose monitors; downloadable and mobile applications used for the monitoring and treatment of diabetes; downloadable computer application software for mobile devices, namely, software for accessing a diabetes patient's medical and physiological data
Disclosed herein are techniques related to making trend based adjustments to insulin dosage. In some embodiments, the techniques may involve obtaining, based on glucose measurements performed on a person, a glucose value and a glucose rate of change (ROC). An initial insulin amount to deliver to the person is calculated based on this glucose value. However, an adjustment value can be obtained in response to a determination that the glucose value exceeds a glucose threshold, and that the glucose ROC exceeds an ROC threshold. The adjustment value represents an adjustment to be applied to the initial insulin amount when the glucose threshold and the ROC threshold are both exceeded. The adjustment value can be predetermined, based on earlier glucose measurements performed on the person. For instance, the adjustment value and the thresholds can be jointly determined through a computer simulation using a person-specific physiological model.
Infusion devices, systems, and related operating methods are provided. A method of detecting an anomalous condition with respect to a fluid path involves providing energy to an actuation arrangement to produce actuation, wherein the actuation arrangement is coupled to a plunger configured to deliver fluid via the fluid path, monitoring an orientation of the actuation arrangement using a sensing arrangement, and detecting an anomalous condition based on the orientation of the actuation arrangement.
A simple, disposable sensing device for sensing an analyte is housed in a single case. The sensing device can transmit sensor data to monitoring device(s). The sensing device includes: a case having a lower major wall adapted to be mounted against a patient's skin, and an upper opposing major wall; a sensor extending from the case and having a distal end sensitive to the analyte to produce an electrical signal, and a proximal end within the case having electrical contacts; a printed circuit board assembly within the case supported by one of the major walls to receive the electrical signal via the electrical contacts; and an elastomeric pad disposed in the case and biased by the other major wall to urge the proximal end of the sensor into contact with the printed circuit board assembly and maintain an electrical connection between the electrical contacts and the printed circuit board assembly.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
Techniques for automatic network configuration based on biometric authentication are described herein. In some embodiments, the techniques may involve obtaining first biometric data from a first device that is substantially attachable to or substantially worn on a body of a user. The techniques may further involve obtaining second biometric data from a second device that is substantially attachable to or substantially worn on the body of the user. The techniques may further involve comparing the first biometric data and the second biometric data. The techniques may further involve determining that the first biometric data and the second biometric data correspond to the same user based on the comparison. The techniques may further involve establishing a communication link with the second device based on the determination that the second device is attached to the body of the user.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
H02J 7/00 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
H04W 4/80 - Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
Disclosed herein are techniques related to predicting a physiological condition of a user. In some embodiments, the techniques may involve obtaining one or more glucose concentration values measured from a user; applying, to the one or more glucose concentration values measured from the user, a first glucose prediction model for a first prediction horizon; obtaining, based on applying the first glucose prediction model, a first predicted glucose value of the user; and predicting a second predicted glucose value of the user for a second prediction horizon that is less than the first prediction horizon, based on the first predicted glucose value and at least one glucose concentration value of the one or more glucose concentration values. In some scenarios, the physiological condition may include, for example, hypoglycemia or hyperglycemia.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
47.
MICRO MODELS AND LAYERED PREDICTION MODELS FOR ESTIMATING SENSOR GLUCOSE VALUES AND REDUCING SENSOR GLUCOSE SIGNAL BLANKING
Methods, systems, and devices for improving continuous glucose monitoring (“CGM”) are described herein. More particularly, the methods, systems, and devices describe applying micro machine learning models to generate predicted sensor glucose values. The system may use the predicted sensor glucose values to display a sensor glucose value to a user. The layered models may generate more reliable sensor glucose predictions across many scenarios, leading to a reduction of sensor glucose signal blanking. The methods, systems, and devices described herein further comprise applying a plurality of micro model to estimate sensor glucose values under outlier conditions. The system may prioritize the models that are trained for certain outlier conditions when the system detects those outlier condition based on the sensor data.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
48.
INTELLIGENT MEDICATION DELIVERY SYSTEMS AND METHODS
Systems, devices, and techniques are disclosed for administering and tracking medicine to patients and providing health management capabilities for patients and caregivers. In some aspects, a system includes an injection pen device including a dose setting mechanism, a dispensing mechanism, and an electronics unit to generate dose data associated with a dispensing event of a dose of the medicine dispensed from the injection pen device and time data associated with the dispensing event; a mobile device in wireless communication to receive and process the dose data; and a software application configured to determine a recommended dose based on health data and contextual data associated with a user of the injection pen device, the software application including a learning dose calculator module to adaptively calculate the recommended dose of the medicine based on time-relevant and circumstances-relevant data specific to the user of the injection pen device.
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
A61M 5/34 - Constructions for connecting the needle
G01D 5/244 - Mechanical means for transferring the output of a sensing memberMeans for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for convertingTransducers not specially adapted for a specific variable using electric or magnetic means influencing characteristics of pulses or pulse trainsMechanical means for transferring the output of a sensing memberMeans for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for convertingTransducers not specially adapted for a specific variable using electric or magnetic means generating pulses or pulse trains
G01D 5/347 - Mechanical means for transferring the output of a sensing memberMeans for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for convertingTransducers not specially adapted for a specific variable using optical means, i.e. using infrared, visible or ultraviolet light with attenuation or whole or partial obturation of beams of light the beams of light being detected by photocells using displacement encoding scales
Medical devices used for the treatment of diabetes; medical apparatus for diabetes, namely, blood glucose monitors; medical equipment, namely, instruments and sensors for measuring blood glucose levels and instruments and sensors for diabetes monitoring; infusion apparatus for therapeutic purposes; injection device for pharmaceuticals; medical test kits for diabetes monitoring for home use; medical apparatus and equipment for use in electronic acquisition, capture, processing, presentation, storage and transmission of patient's medical and physiological data for use in programming, monitoring and operating medical devices used for the treatment and management of diabetes.
Medical devices used for the treatment of diabetes; medical apparatus for diabetes, namely, blood glucose monitors; medical equipment, namely, instruments and sensors for measuring blood glucose levels and instruments and sensors for diabetes monitoring; infusion apparatus for therapeutic purposes; injection device for pharmaceuticals; medical test kits for diabetes monitoring for home use; medical apparatus and equipment for use in electronic acquisition, capture, processing, presentation, storage and transmission of patient's medical and physiological data for use in programming, monitoring and operating medical devices used for the treatment and management of diabetes.
51.
ERROR HANDLING IN INFUSION DEVICES WITH DISTRIBUTED MOTOR CONTROL AND RELATED OPERATING METHODS
Techniques disclosed herein relate to operating a motor using a first control module and a second control module. The techniques may involve detecting, by the first control module, after loading application code for execution by the first control module and the second control module, an anomalous condition. The techniques may further involve in response to detection of the anomalous condition, disabling, by the first control module, input power to the motor. The techniques may further involve resetting the first control module and the second control module to a boot loader stage.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
A61M 5/168 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
52.
Nutritional content determination based on gesture detection data
Techniques disclosed herein relate to nutritional content determination based on gesture detection data. In some embodiments, the techniques involve obtaining gesture detection data corresponding to consumption of a food item or a drink; determining, based on the gesture detection data, nutritional content of the food item or the drink; and causing delivery of insulin in accordance with the nutritional content of the food item or the drink.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
H04W 4/80 - Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
53.
DETERMINATION OF ADJUSTMENTS TO FLUID DELIVERY SETTINGS
Infusion systems, infusion devices, and related operating methods are provided. In one example, a computer-implemented method includes identifying, based on an input meal size category of a meal event and a plurality of groups of historical meal events associated with a plurality of meal size categories for a person, a group of historical meal events having an associated meal size category that corresponds to the input meal size category, determining at least one person-specific variable representative of historical meal events in the identified group of historical meal events, determining a bolus insulin dosage based at least in part on the at least one person-specific variable, and causing administration of insulin to the person based on the bolus insulin dosage.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
The disclosed techniques include applying one or more voltage pulses to a working electrode of a sensor probe. The techniques may also involve measuring, using a current sensor, a set of one or more current responses corresponding to the applied one or more voltage pulses, wherein the set of one or more current responses form a quasi-Cottrell profile that approximates a portion of a Cottrell curve. The techniques may further involve comparing a characteristic of the quasi-Cottrell profile to sets of predetermined Cottrell profiles. The techniques may further involve calibrating the current sensor based on the comparison.
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/1495 - Calibrating or testing in vivo probes
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
The present technology includes, for example, an insertion assembly comprising a frame including a tubular sidewall defining an internal cavity and a slot extending longitudinally along a portion of the sidewall. The insertion assembly further comprises a medical device configured to be inserted into the user's skin and a carrier carrying the medical device and at least partially disposed within the internal cavity of the frame. The carrier can be axially movable within the frame from a first, cocked position to a second extended position proximate. The carrier can include a protrusion disposed within the slot of the frame and configured to slide within the slot when the carrier moves axially within the frame. A ratio of a height of the protrusion to a width of the protrusion is greater than 1.
The present technology includes, for example, a seal assembly for a medicament infusion device. The seal assembly can comprise an annular dock seal comprising an upper surface, a lower surface, a radially inner surface, a radially outer surface, and a through-hole extending between the radially outer and inner surfaces and defining a first fluid flow path. The seal assembly can comprise a seal housing at least partially surrounding the dock seal and having an upper flange, a lower flange, a side portion configured to contact at least a portion of the radially outer surface of the dock seal to define an annular channel between the side portion of the seal housing and the radially outer surface of the dock seal, and a second fluid flow path extending through the side portion such that the second fluid flow path is in fluid communication with the first fluid flow path.
A flexible tubing for a cannula has a hollow tubing body having a length dimension from a first end to a second end, and an outer diameter of no more than 0.9 mm. The tubing body has a section of enhanced flexibility of a greater flexibility than one or more other sections of the tubing body. The section of enhanced flexibility is spaced from the first end of the tubing body by a distance D, where D is within a range of 3.0 mm to 5.0 mm for a flexible tubing having a length of about 9.0 mm, and where D is within a range of 1.0 mm to 2.9 mm for a flexible tubing having a length of about 6.0 mm.
Techniques for automatically configuring a medical device with user-specific configuration data are provided. In some embodiments, the techniques may involve determining, by a first medical device, that the first medical device is being removed from service on a patient based at least in part on detecting removal of a portion of the first medical device from contact with or being coupled to the patient. The techniques may further involve in response to determining that the first medical device is being removed from service on the patient, communicating user-specific configuration data used by the first medical device to a second medical device, wherein the second medical device is a replacement medical device for the first medical device.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
59.
USE OF ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY (EIS) IN GROSS FAILURE ANALYSIS
Electrochemical Impedance Spectroscopy (EIS) is used in conjunction with continuous glucose monitors and continuous glucose monitoring (CGM) to enable in-vivo sensor calibration, gross (sensor) failure analysis, and intelligent sensor diagnostics and fault detection. An equivalent circuit model is defined, and circuit elements are used to characterize sensor behavior.
A61B 5/0537 - Measuring body composition by impedance, e.g. tissue hydration or fat content
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/0538 - Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1468 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/1495 - Calibrating or testing in vivo probes
A continuous glucose monitoring system may utilize electrode current (Isig) signals, Electrochemical Impedance Spectroscopy (EIS), and Vcntr values to optimize sensor glucose (SG) calculation in such a way as to enable reduction of the need for blood glucose (BG) calibration requests from users.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1468 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means
This disclosure generally relates to medical devices that include a transmitter assembly positioned on top of a sensor assembly. A sensor assembly includes a sensor base having a bottom surface and a top surface having an interface. The interface accommodates a sensor stack that includes at least one sensor head having electrical contact pads connected to an elastomeric connector. The sensor assembly further includes a mounting base having a first side that attaches to the bottom surface of the sensor base, and a second side that adheres to a patient's skin. A transmitter assembly includes a transmitter shell and a transmitter cap having an interface that engages with the sensor base. Also, the transmitter assembly includes electrical contacts disposed on the transmitter cap that connect with the electrical contact pad(s) of the sensor assembly.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A method of estimating a value of a physiological condition may be performed by an electronic device including one or more processors. The method involves generating a simulated measurement using an actual measurement from a first sensor as input to a translation model. The actual measurement includes one or more measurement parameters output by the first sensor as an indication of the value of the physiological condition. The simulated measurement includes one or more measurement parameters that a second sensor would output given the same value of the physiological condition. The method further involves estimating the value of the physiological condition through inputting the simulated measurement to an estimation model. The estimation model is configured to map the one or more measurement parameters that the second sensor would output to an estimated value for the physiological condition.
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1495 - Calibrating or testing in vivo probes
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G06F 18/214 - Generating training patternsBootstrap methods, e.g. bagging or boosting
G06N 3/088 - Non-supervised learning, e.g. competitive learning
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G16H 70/60 - ICT specially adapted for the handling or processing of medical references relating to pathologies
63.
METHODS, SYSTEMS, AND DEVICES FOR CALIBRATION AND OPTIMIZATION OF GLUCOSE SENSORS AND SENSOR OUTPUT
A continuous glucose monitoring system may utilize externally sourced information regarding the physiological state and ambient environment of its user for externally calibrating sensor glucose measurements. Externally sourced factory calibration information may be utilized, where the information is generated by comparing metrics obtained from the data used to generate the sensor's glucose sensing algorithm to similar data obtained from each batch of sensors to be used with the algorithm in the future. The output sensor glucose value of a glucose sensor may also be estimated by analytically optimizing input sensor signals to accurately correct for changes in sensitivity, run-in time, glucose current dips, and other variable sensor wear effects. Correction actors, fusion algorithms, EIS, and advanced ASICs may be used to implement the foregoing, thereby achieving the goal of improved accuracy and reliability without the need for blood-glucose calibration, and providing a calibration-free, or near calibration-free, sensor.
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61B 5/1468 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
G01N 27/02 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
64.
METHODS, SYSTEMS, AND DEVICES FOR IMPROVED SENSORS FOR CONTINUOUS GLUCOSE MONITORING
Methods, systems, and devices for continuous glucose monitoring. More particularly, the methods, systems, and devices describe a working electrode with a GOx sensor and a background electrode in which the background electrode has no GOx sensor. The system may then compare the first signal and the second signal to detect ingestion of a medication by the user. The system may generate a sensor glucose value based on the comparison.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
65.
AMBULATORY INFUSION PUMP DEVICE WITH AN EPICYCLIC INSERTER
In some embodiments, an infusion device can include a reservoir configured to hold a medicament, a first epicyclic gear arrangement comprising a first output, a second epicyclic gear arrangement comprising a second output, a first trocar coupled to the first output and movably coupled to a sensor electrode, and a second trocar coupled to the second output and movably coupled to an infusion cannula that is fluidically coupled to the reservoir. Actuation of the first epicyclic gear arrangement can drive linear travel of the first trocar and/or the sensor electrode, and actuation of the second epicyclic gear arrangement can drive linear travel of the second trocar and/or the infusion cannula.
An analyte sensor device includes a housing, a sensor, and a printed circuit board assembly (PCBA) within the housing and including a circuit and a first plurality of contacts. The sensor includes a proximal end within the housing and a distal end outside of the housing. The proximal end includes a second plurality of contacts electrically connected to the first plurality of contacts on the PCBA. The distal end includes one or more electrodes configured to measure a concentration level of an analyte in a body of a user. The circuit is operable to detect electrical connection between the first plurality of contacts and the second plurality of contacts within the housing while the distal end of the sensor is outside the body of the user or a fluid.
Techniques for contextual adjustment of insulin adjustment curves are provided. In some embodiments, the techniques may involve identifying a reference insulin absorption parameter for a patient based on demographic information. The techniques may further involve determining an adjusted insulin absorption parameter based on the reference insulin absorption parameter and context of the patient. The techniques may further involve delivering insulin to the patient based on the adjusted insulin absorption parameter.
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
Ambulatory infusion pumps, durable assemblies, and disposable assemblies, including energy sources. reservoirs, baseplates, and related components therefor, as well as component combinations and related methods.
A system includes one or more processors and one or more processor-readable storage media storing instructions which, when executed by the one or more processors, cause performance of obtaining an insulin-on-board (IOB) value, wherein the IOB value is a quantity of insulin remaining in a patient following delivery of a bolus of insulin, scaling a total daily dose (TDD) value by a factor, to generate a result having a value that is less than the TDD value, based on determining that the IOB value is greater than the result, identifying a condition in which the patient's glucose level will continue to decrease after suspension of basal insulin dosage delivery, and responsive to identifying the condition, causing performance of an action for preventing the patient's glucose level from falling into a hypoglycemic range in combination with the suspension of basal insulin dosage delivery.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
70.
DETERMINATION OF ADJUSTMENTS TO FLUID DELIVERY SETTINGS
Techniques disclosed herein relate generally to diabetes therapy management. In some examples, the techniques involve obtaining therapy-related data (e.g., including sensor glucose data and meal data) of a user of an insulin delivery device for a time period of a plurality of time periods, determining whether the therapy-related data associated with the time period is well-fit data by determining whether a physiological model for the user can be fitted to the therapy-related data associated with the time period, determining one or more parameters of the physiological model by fitting the physiological model to well-fit data associated with the time period, and causing the insulin delivery device to deliver insulin to the user based on the one or more parameters of the physiological model.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
Embodiments are provided for dynamic management of charge. The techniques may involve charging, using a first charging rate, an energy storage element to an intermediate state of charge, wherein the energy storage element is interchangeable with an in-use energy storage element. The techniques may further involve responsive to at least an identification of an anomalous condition of a device powered by the in-use energy storage element, the anomalous condition resulting in the in-use energy storage element being discontinued from use, charging, using a second charging rate, the energy storage element to a target state of charge, wherein the second charging rate is different from the first charging rate.
A device includes a glucose monitor comprising at least one sensor electrode configured to sense signals indicative of interstitial glucose level of a patient. The device also includes a memory and one or more processors implemented in circuitry and in communication with the memory. The one or more processors are configured to cause delivery of a cleaning electrical current to the at least one sensor electrode. The cleaning electrical current is one or more electrochemical cleaning pulses configured to at least partially remove, in vivo and from the sensor electrode, excipients associated with the delivery of a fluid that includes insulin.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1468 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
73.
IMPLANTABLE POLYMER SURFACES EXHIBITING REDUCED IN VIVO INFLAMMATORY RESPONSES
Embodiments of the invention provide optimized polymeric surfaces adapted for use with implantable medical devices as well as methods for making and using such polymeric surfaces. These polymer surfaces have a constellation of features that function to inhibit or avoid an inflammatory immune response generated by implantable medical devices. Typical embodiments of the invention include an implantable glucose sensor used in the management of diabetes having a polymer surface with the disclosed constellation of features.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving oxidoreductase
C12Q 1/54 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving glucose or galactose
74.
INSULIN INFUSION DEVICE WITH CONFIGURABLE TARGET BLOOD GLUCOSE VALUE FOR AUTOMATIC BASAL INSULIN DELIVERY OPERATION
Techniques disclosed herein relate to configurable target glucose values. In some embodiments, the techniques may involve modifying a glucose setpoint from a first target value to a second target value, wherein the second target value is lower than the first target value. The techniques may further involve regulating a glucose level of a patient to the modified glucose setpoint by controlling insulin delivery. The techniques may further involve after a time period has elapsed, reverting the glucose setpoint to the first target value.
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
75.
SYSTEMS AND METHODS FOR ASSESSING SENSOR SURFACE AREA ENCAPSULATION IN VITRO AND IN VIVO
A glucose sensor includes a working electrode, sensor electronics configured to periodically measure electrode current signal (Isig) values for the working electrode and counter voltage values (Vcntr) for the glucose sensor, one or more processors, and one or more processor-readable media. The one or more processor-readable media stores instructions which, when executed by the one or more processors, cause performance of: generating Electrochemical Impedance Spectroscopy (EIS) parameter values for the working electrode based on an EIS procedure; estimating a reaction surface area of the glucose sensor based on least one of Isig values, Vcntr values, or the EIS parameter values; determining a difference between the estimated reaction surface area and an expected reaction surface area of the glucose sensor; comparing the determined difference to a predetermined threshold value; and adjusting a calibration factor when the determined difference is below the predetermined threshold value.
A method of optimizing operation of a glucose sensor includes performing an electrochemical impedance spectroscopy (EIS) procedure to obtain imaginary impedance values for an electrode of a glucose sensor, calculating a change value as a difference between a threshold reference for the imaginary impedance values and a most-recent imaginary impedance value, and obtaining measurements of the calibration factor for the glucose sensor. The method also includes comparing the change value to a first threshold and the calibration factor to a second threshold and determining, based on the comparison, whether sensor data from the glucose sensor is valid.
Embodiments of the invention provide amperometric analyte sensors having membranes made from materials selected to transport analytes such as glucose to an enzyme within the sensor while simultaneously inhibiting the movement of interfering species such as acetaminophen to the electrode within the sensor. While embodiments of the invention can be used in a variety of contexts, typical embodiments of the invention include glucose or ketone sensors used in the management of diabetes.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
Techniques for detection of occurrence of a meal are provided. In some embodiments, the techniques may involve obtaining a plurality of glucose measurements indicative of a glucose level in a body of a patient during an analysis interval. The techniques may involve determining one or more glucose measurement statistics based on the plurality of glucose measurements. The techniques may involve determining a likelihood of the patient having consumed a meal during the analysis interval based on the one or more glucose measurement statistics that are correlative to an occurrence of a meal for the patient. The techniques may involve detecting an occurrence of the meal during the analysis interval based on the likelihood of the patient having consumed the meal during the analysis interval.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G06N 7/01 - Probabilistic graphical models, e.g. probabilistic networks
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Educational toys, games and playthings. Providing education relating to diabetes for children; educational and instruction services relating to arts, crafts, sports and general knowledge; providing online non-downloadable electronic publications in the nature of books, manuals, articles, newsletters and brochures in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect monitor and treat diabetes. Providing treatment information for diabetes to children; providing medical information; providing medical information in the field of detection, monitoring and treatment of diabetes and the use of medical devices.
80.
BLOOD GLUCOSE ESTIMATION BASED ON RATE OF CHANGE INFORMATION
Disclosed herein are techniques related to blood glucose estimation based on rate of change information. In some embodiments, the techniques may involve obtaining a sensor glucose value. The techniques may also involve calculating a sensor glucose rate of change based on the sensor glucose value. The techniques may further involve determining an estimated glucose bias value corresponding to the sensor glucose rate of change. The determining may be based on applying, to the sensor glucose rate of change, a predictive model for estimating glucose bias values corresponding to differences between blood glucose measurements and sensor glucose values. Additionally, the techniques may involve adjusting the sensor glucose value based on accounting for the estimated glucose bias value.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
81.
INTELLIGENT MEDICATION DELIVERY SYSTEMS AND METHODS FOR MEDICINE DOSE CALCULATION AND REPORTING
Systems, devices, and techniques are disclosed for administering and tracking medicine to patients and providing health management capabilities for patients and caregivers. In some aspects, a system includes an injection pen device in communication with a mobile communication device having a software application to determine a recommended dose based on prior dose data, analyte data, and nutrient data and to generate a report illustrative of a relationship between the medicine data, the health data, and the contextual data.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
A61M 5/24 - Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
Techniques disclosed herein relate to food analysis and glucose level management. In some examples, the techniques involve determining a consumption of a first food item by a user, receiving data indicative of a glucose level of the user, determining an effect of the first food item on the glucose level of the user based on a change of the glucose level of the user, and storing the effect of the first food item on the glucose level of the user to a database that includes data indicating effects of individual food items on the glucose level of the user. In some examples, the techniques also involve providing one or more recommendations for managing the glucose level of the user based on the data in the database and a food item consumed by the user.
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
Disclosed herein are techniques for communication of information. In some embodiments, the techniques involve receiving, at an intermediate device from a remote device, a request to initiate a first communication session. The techniques may further involve responsive to receiving the request, establishing a second communication session between the intermediate device and a medical device. The techniques may further involve responsive to establishing the second communication session, automatically transmitting, by the intermediate device to the remote device, an acknowledgement that establishes the first communication session between the intermediate device and the remote device. The techniques may further involve streaming updated control parameters to the medical device via the second communication session.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G05B 15/02 - Systems controlled by a computer electric
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16Z 99/00 - Subject matter not provided for in other main groups of this subclass
84.
SYSTEMS AND METHODS FOR DRIVING ELECTROMAGNETIC MOTORS OF MEDICAMENT INFUSION PUMPS
Systems and methods for driving electrical motors of medicament infusion pumps are disclosed. An infusion device for delivering a medicament to a body of a user can include a reservoir to contain medicament, a dispenser to cause medicament to be moved out of the reservoir, and a motor operably coupled to the dispenser. The motor can include a stator defining a central opening and a rotor removably disposed therein. A controller coupled to the stator is configured to (1) supply a first signal to the stator to cause the rotor to rotate in a first direction for a first rotational amount less than a full rotation; and (2) to then supply a second signal to the stator to cause the rotor to rotate in a second, opposite direction for a second rotational amount greater than the first, thereby causing medicament to be dispensed from the reservoir via the dispenser.
A sensor device includes a housing configured to be secured to a patient and a seal structure located within the housing. A sensor probe having at least one substrate is supported by the housing. The substrate has a first length portion and a second length portion. The first length portion is external to the housing and is configured to be inserted into the patient when the housing is secured to the patient. The second length portion is in or on the housing and has a section that extends through the seal structure. That section has at least one side edge having an undulating edge pattern that enhances a seal effect of the seal structure at the section of the second length portion of the at least one substrate. The undulating edge pattern may be an edge wave pattern having a plurality of peaks or a plurality of valleys.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
86.
COLOROMETRIC SENSOR FOR THE NON-INVASIVE SCREENING OF GLUCOSE IN SWEAT IN PRE AND TYPE 2 DIABETES
Described here are patches and methods for measuring glucose in sweat (and tears and the like). In general, the patches comprise an adhesive layer adapted to bond to skin of an individual, a substrate layer disposed over the adhesive layer and comprising a glucose sensing complex including a chromogen that changes color in the presence of certain concentrations of glucose, and a cover. In typical embodiments, the substrate layer has elements formed to direct and accumulate sweat that migrates from the skin of the individual to the glucose sensing complex. Methods of using the invention can comprise cleaning the skin surface, collecting sweat in a patch comprising this microfluidic constellation of elements, and observing concentrations of glucose collected in the sweat, for example either visually, or by using a smartphone or other computer processing device.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/1477 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means non-invasive
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
G01N 33/66 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving blood sugars, e.g. galactose
Disclosed herein are techniques related to product consumption recommendations. In some embodiments, the techniques may involve determining, based on glucose data of a user and activity data indicating movement of the user during an activity, a recommendation associated with a consumption of a product by the user to maintain a glucose level within a target range during the activity, and, in response to the recommendation indicating that the consumption of the product is recommended, providing the recommendation to the user.
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1477 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means non-invasive
G06K 7/10 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation
G06K 7/14 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation using light without selection of wavelength, e.g. sensing reflected white light
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
88.
PREDICTIVE INFUSION DEVICE OPERATIONS AND RELATED METHODS AND SYSTEMS
Techniques for fluid delivery are provided. In some embodiments, the techniques may involve monitoring a value representative of a physiological condition in a body of a user. The techniques may further involve operating in a first operational mode of a fluid delivery device based on the value representative of the physiological condition. The techniques may further involve transitioning to a second operational mode of the fluid delivery device based at least in part on the value representative of the physiological condition relative to a threshold and a time that has been spent in the first operational mode of the fluid delivery device.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16Z 99/00 - Subject matter not provided for in other main groups of this subclass
89.
DETERMING A WIRELESS COMMUNICATION INTERFACE FOR COMMUNICATING IN A NETWORK INCLUDING A MEDICAL DEVICE
Disclosed are methods and corresponding systems for determining a wireless communication interface for communicating between a first device and a second device. The first device and the second device can be part of a network that includes a medical device. In some instances, the medical device is the source or destination of data being communicated between the first device and the second device. The wireless communication interface can be one of a plurality of wireless communication interfaces and is determined based on one or more factors including: a proximity of the first device to the second device, a quality of service level of a communication link established using the wireless communication interface, a security level of the data being communicated between the first device and the second device, or any combination thereof.
Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes, and associated architectures, as well as methods for making and using such sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Computer hardware for use in electronic acquisition, capture, processing, presentation, storage and transmission of patient's medical and physiological data for use in programming, monitoring and operating medical devices used for the treatment and management of diabetes Medical devices used for the treatment of diabetes; medical apparatus for diabetes, namely, blood glucose monitors; medical equipment, namely, instruments and sensors for measuring blood glucose levels and instruments and sensors for diabetes monitoring; infusion apparatus for therapeutic purposes; injection device for pharmaceuticals; medical test kits for diabetes monitoring for home use
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Computer hardware for use in electronic acquisition, capture, processing, presentation, storage and transmission of patient's medical and physiological data for use in programming, monitoring and operating medical devices used for the treatment and management of diabetes Medical devices used for the treatment of diabetes; medical apparatus for diabetes, namely, blood glucose monitors; medical equipment, namely, instruments and sensors for measuring blood glucose levels and instruments and sensors for diabetes monitoring; infusion apparatus for therapeutic purposes; injection device for pharmaceuticals; medical test kits for diabetes monitoring for home use
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Downloadable and recorded computer software and downloadable mobile applications used to measure, collect, transmit, monitor, track and analyze diabetes information and patient data; Downloadable and recorded computer software and downloadable mobile applications used to operate, monitor and manage medical devices, insulin pumps and glucose monitors; Downloadable and recorded computer software and downloadable mobile applications used for the monitoring and treatment of diabetes; computer hardware and peripherals for use in the medical field; downloadable electronic publications in the nature of books, manuals, articles, newsletters and brochures in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes Medical devices used for the treatment of diabetes; medical apparatus for diabetes, namely, blood glucose monitors; medical equipment, namely, instruments and sensors for measuring blood glucose levels and instruments and sensors for diabetes monitoring; infusion apparatus for therapeutic purposes; injection device for pharmaceuticals; medical test kits for diabetes monitoring for home use Providing courses of instruction in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes; providing online non-downloadable electronic publications in the nature of books, manuals, articles, newsletters and brochures in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes Providing temporary use of non-downloadable computer software used for the detection, monitoring, management, and treatment of diabetes; providing temporary use of non-downloadable computer software used to operate, monitor and manage medical devices, insulin pumps and glucose monitors Providing medical information; providing medical information via a website; providing medical information in the field of detection, monitoring and treatment of diabetes and the use of medical devices used to detect, monitor and treat diabetes
94.
Methods, systems, and devices for calibration and optimization of glucose sensors and sensor output
A continuous glucose monitoring system may utilize externally sourced information regarding the physiological state and ambient environment of its user for externally calibrating sensor glucose measurements. Externally sourced factory calibration information may be utilized, where the information is generated by comparing metrics obtained from the data used to generate the sensor's glucose sensing algorithm to similar data obtained from each batch of sensors to be used with the algorithm in the future. The output sensor glucose value of a glucose sensor may also be estimated by analytically optimizing input sensor signals to accurately correct for changes in sensitivity, run-in time, glucose current dips, and other variable sensor wear effects. Correction actors, fusion algorithms, EIS, and advanced ASICs may be used to implement the foregoing, thereby achieving the goal of improved accuracy and reliability without the need for blood-glucose calibration, and providing a calibration-free, or near calibration-free, sensor.
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61B 5/1468 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
G01N 27/02 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
95.
Continuous analyte sensor quality measures and related therapy actions for an automated therapy delivery system
Techniques disclosed herein relate to continuous analyte sensor quality measures. In some embodiments, the techniques may involve obtaining a sensor-generated value that is indicative of a physiological characteristic of a user of a medical device. The techniques may further involve causing, in response to obtaining a sensor quality metric that indicates accuracy of the sensor-generated value, configuration of a quality-specific operating mode of the medical device, the quality-specific operating mode comprising regulation of basal and bolus deliveries of a fluid medication based on the obtained sensor quality metric.
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
96.
Regulating delivery of insulin to a body of a user by a fluid delivery device
Techniques related to temporary setpoint values are disclosed. The techniques may involve causing operation of a fluid delivery device in a closed-loop mode for automatically delivering fluid based on a difference between a first setpoint value and an analyte concentration value during operation of the fluid delivery device in the closed-loop mode. Additionally, the techniques may involve obtaining a second setpoint value. The second setpoint value may be a temporary setpoint value to be used for a period of time to regulate fluid delivery, and the second setpoint value may be greater than the first setpoint value. The techniques may further involve causing operation of the fluid delivery device for automatically reducing fluid delivery for the period of time based on the second setpoint value.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16Z 99/00 - Subject matter not provided for in other main groups of this subclass
Techniques disclosed herein relate generally to notification generation in a medical device system. In some embodiments, the techniques involve detecting a failure to receive an acknowledgement of a first notification at a mobile device within a predetermined time frame, and delivering, to a medical device, a second notification that indicates the failure to receive the acknowledgement of the first notification at the mobile device within the predetermined time frame.
G06F 11/07 - Responding to the occurrence of a fault, e.g. fault tolerance
G06F 11/14 - Error detection or correction of the data by redundancy in operation, e.g. by using different operation sequences leading to the same result
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
98.
Personalized closed loop optimization systems and methods
Techniques disclosed herein involve automatically adjusting a control parameter for an operating mode of a medical device. In some embodiments, the techniques involve obtaining data pertaining to a physiological condition of a patient during operation of the medical device. In some embodiments, the techniques further involve determining an optimized value for the control parameter using the data pertaining to the physiological condition of the patient and a cost function, wherein the cost function disproportionately penalizes for an amount of time that a physiological parameter is below a lower bound of a target range and includes a first weighting factor that is dependent on an amount of time that the physiological parameter is outside of the target range, and a second weighting factor, different from the first weighting factor, dependent on the amount of time that the physiological parameter is below the lower bound of the target range.
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
99.
CONTROLLING MEDICAL INFUSION DEVICE OPERATION AND FEATURES BASED ON DETECTED PATIENT SLEEPING STATUS
A processor-implemented method for controlling delivery of insulin to a user of an insulin infusion device involves: obtaining user status sensor data indicative of a sleeping status of a user of an insulin infusion device, and controlling operation of the insulin infusion device in accordance with the sleeping status of the user.
A continuous glucose monitoring system may utilize externally sourced information regarding the physiological state and ambient environment of its user for externally calibrating sensor glucose measurements. Externally sourced factory calibration information may be utilized, where the information is generated by comparing metrics obtained from the data used to generate the sensor's glucose sensing algorithm to similar data obtained from each batch of sensors to be used with the algorithm in the future. The output sensor glucose value of a glucose sensor may also be estimated by analytically optimizing input sensor signals to accurately correct for changes in sensitivity, run-in time, glucose current dips, and other variable sensor wear effects. Correction actors, fusion algorithms, EIS, and advanced ASICs may be used to implement the foregoing, thereby achieving the goal of improved accuracy and reliability without the need for blood-glucose calibration, and providing a calibration-free, or near calibration-free, sensor.
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61B 5/1468 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
G01N 27/02 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
