JIANGSU KANGREN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO. LTD. (China)
Inventor
Xiao, Wei
Liu, Shijuan
Wang, Zhendong
Yang, Xiaoxiao
Zhang, Siyuan
Fan, Yewen
Bai, Weirong
Deng, Chenchen
Cao, Miaomiao
Wang, Jing
Abstract
Disclosed is an immune response-improving composition, characterized in that the composition comprises, in parts by weight, 5-50 parts of Wolfiporia extensa, 3-30 parts of Lentinula edodes, 2-20 parts of Lycium chinense, 1.5-20 parts of Agaricus subrufescens, 1.5-20 parts of Grifola frondosa, 1.5-20 parts of lily, and 1.5-10 parts of ginseng. The composition and a preparation thereof can promote the proliferation of mouse thymus and spleen cells, increasing the ability of mouse reticuloendothelial system to ingest inert carbon particles, and achieving a significant anti-tumor effect in mice with S180 tumors.
JIANGSU KANGREN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO. LTD. (China)
Inventor
Xiao, Wei
Li, Manman
Zhang, Haitao
Fan, Yewen
Bai, Weirong
Jia, Mingqiang
Abstract
Disclosed is a composition for alleviating physical fatigue, characterized in that: the composition comprises, by weight, 3 to 9 parts of Polygonati rhizoma, 1 to 6 parts of Ganoderma, 1 to 6 parts of Phyllanthi fructus and 1 to 4 parts of Rhodiolae crenulatae radix et rhizoma. Experiments show that the process for extracting the composition extract is simple. In addition, the raw materials used in the formula of the composition are rationally compatible, and the preparation process is simple. The composition can significantly prolong weight-bearing swimming time of mice and reduce the area under a blood lactic acid curve and the serum urea nitrogen content of the mice at three time points before and after exercise. Thus, the composition has the function of alleviating physical fatigue.
JIANGSU KANGREN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO. LTD. (China)
Inventor
Xiao, Wei
Fan, Yewen
Liu, Shijuan
Wang, Zhendong
Zhang, Haitao
Li, Manman
Bai, Weirong
Abstract
Provided is a composition having an immunity-enhancing function, comprising, in parts by weight: 1-12 parts of poria, 0.1-6 parts of Lycium chinense, 0.1-6 parts of semen coicis, 0.1-4 parts of ginseng, and 0.1-4 parts of Glycyrrhiza uralensis. The combined use of the five medicines can promote the cellular immunity and phagocytosis of mice, and has a significant effect of enhancing immunity.
JIANGSU KANGREN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO. LTD. (China)
Inventor
Xiao, Wei
Gao, Ruyi
Cao, Miaomiao
Guo, Xiaoli
Deng, Chenchen
Xu, Mingjun
Liu, Wenying
Abstract
Provided is a composition having digestion promoting function, comprising, in parts by weight, 1-10 parts of hawthorn, 1-15 parts of germinated barley, 1-10 parts of atractylodes macrocephala, 1-15 parts of dried tangerine peel, and 1-10 parts of radix pseudostellariae. The traditional Chinese medicine raw materials are prepared into tablets through extraction and concentration combined with the modern technology. The present invention screens the types and the dosage ratios of excipients, overcomes the bitterness and astringency of traditional Chinese medicine chewable tablets, so that the obtained tablet is good in chewiness, sweet and sour in taste, and beautiful in appearance, and has the health-care function of promoting digestion.
JIANGSU KANGREN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO. LTD. (China)
Inventor
Xiao, Wei
Ding, Yan
Liu, Shijuan
Wang, Jing
Bai, Weirong
Wang, Zhendong
Deng, Chenchen
Abstract
Disclosed is a composition for protecting liver, a preparation method therefor, and application thereof. The composition comprises Puerariae Lobatae Radix, Crataegi Fructus, Taraxaci Herba, Chrysanthemi Flos, and Citri Reticulatae Pericarpium.
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A23G 3/48 - Sweetmeats, confectionery or marzipanProcesses for the preparation thereof characterised by the composition containing plants or parts thereof, e.g. fruits, seeds, extracts
JIANGSU KANGREN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO. LTD. (China)
Inventor
Xiao, Wei
Yu, Guifang
Hu, Baoling
Hu, Junhua
Yan, Xianguang
Wang, Jing
Hu, Hanfei
Wei, Yingchun
Wang, Zhenzhong
Abstract
A method for determining the composition of lutein, in which high performance liquid chromatography is employed for measurement. The chromatographic conditions comprise: using YMC Carotenoid C30 as a chromatographic column; using methanol/water as mobile phase A and methyl tert-butyl ether as mobile phase B; the elution procedure comprises 0-30 min with 0% to 50% B, and 30-40 min with 50% B, where the ratio of methanol to water is 88-100:12-0. The method uses a high-active ingredient all-trans lutein as a measurement index, and can accurately and effectively evaluate the quality of a lutein product. The chromatographic conditions used can achieve effective separation of all-trans lutein and main cis-isomers and isomers thereof and accurate quantification of the all-trans lutein.
JIANGSU KANGREN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO. LTD. (China)
Inventor
Xiao, Wei
Cao, Miaomiao
Gao, Ruyi
Liu, Shijuan
Xu, Mingjun
Yu, Guifang
Zhang, Haitao
Bai, Weirong
Abstract
A composition with a hypolipidemic function, a preparation method therefor and an application thereof. The composition comprises fructus lycii, fructus hippophae, radix notoginseng, and flos carthami.
JIANGSU KANGREN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO. LTD. (China)
Inventor
Xiao, Wei
Bai, Weirong
Yang, Xufang
Yu, Guifang
Guo, Xiaoli
Wu, Yun
Abstract
Disclosed is a composition with a chloasma removal function, comprising 1-12 parts of Angelicae sinensis radix, 1-15 parts of Paeoniae radix alba, 1-10 parts of Cyperi rhizoma, 1-12 parts of Cuscutae semen and 2-10 parts of Glycyrrhizae radix et rhizoma. Drugs, health-care products and food products containing the composition are selected from tablets, chewable tablets, effervescent tablets, hard capsules, soft capsules, granules, syrups, wines and an oral liquid. Experiments have shown that the composition and a preparation involving same can significantly reduce the average chloasma area of a subject and the color score, and no new chloasma is generated, and compared with a blank control group, the composition and the preparation involving same have significant differences.
JIANGSU KANGREN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO. LTD. (China)
Inventor
Xiao, Wei
Wang, Zhendong
Liu, Shijuan
Yang, Xiaoxiao
Zhang, Siyuan
Abstract
An immunity-enhancing composition, comprising the following components in parts by weight: 28-34 parts of Wolfiporia extensa, 14-18 parts of Agaricus subrufescens, 8-12 parts of Grifola frondosa, and 4-6 parts of Panax ginseng. The raw ingredients Wolfiporia extensa, Agaricus subrufescens, Grifola frondosa, and Panax ginseng are all both food and medicine, and have no toxic side effects. When preparing crude polysaccharide extracts, a water extraction process is employed for performing multiple extractions to improve the dissolution of the crude polysaccharides in the raw materials, and a vacuum concentration process is used for enriching and concentrating the raw material extract solution, increasing the crude polysaccharide content, protecting the active ingredients from being destroyed, and retaining the characteristic aroma components and flavours of the raw materials, benefiting digestion and absorption by the body.
JIANGSU KANGREN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO. LTD. (China)
Inventor
Xiao, Wei
Xu, Mingjun
Deng, Chenchen
Gao, Ruyi
Cao, Miaomiao
Bai, Weirong
Abstract
A composition having an immunity-enhancing function and a preparation method therefor. The composition comprises any four or more of fructus ligustri lucidi, Herba Ecliptae, radix astragali, codonopsis pilosula, and poria cocos.