COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING KIDNEY AND/OR LIVER DISEASES VIA ANTIINFLAMMATION, ANTIOXIDATION, ANTIFIBROSIS, AND UREMIC TOXIN EXCRETION, COMPRISING COMPLEX (NEPROBIN) OF GANODERMA LUCIDUM EXTRACT AND ROBINIA PSEUDOACACIA FLOWER EXTRACT AS ACTIVE INGREDIENT
The present invention relates to a composition for preventing, ameliorating, or treating kidney and liver diseases, comprising a complex (NEPROBIN) of Ganoderma lucidum extract and Robinia pseudoacacia flower extract as an active ingredient. The complex provided from the present invention exhibits excellent effects in preventing kidney damage, maintaining kidney function, and regenerating kidney tissue by means of inhibition of NO production, reduction in cytokine (TNF-a) and Crp gene expression, increase in glutathione, reduction in ROS production, and increase in uremic toxin excretion, and exhibits excellent effects in preventing liver damage and improving liver function by means of inhibition of NO production, reduction in cytokine (IL6) and MCP1 and CXCL1 gene expression, increase in glutathione, suppression of expression of fibrosis markers (ACTA2, Vim, COL3A1) of hepatic stellate cells, restoration of GSH in liver tissue, increase in antioxidant enzyme activity, and suppression of expression of antiinflammatory- and antifibrotic-related genes and proteins, and thus, the complex is applicable as a pharmaceutical composition for preventing or treating kidney and/or liver diseases, and as a health functional food and food composition for preventing or ameliorating liver diseases.
COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING OBESITY, COMPRISING, AS ACTIVE INGREDIENT, COMPLEX (ASC COMPLEX) OF WITHANIA SOMNIFERA EXTRACT AND SIBERIAN CHRYSANTHEMUM EXTRACT
The present invention relates to a composition for preventing, improving or treating obesity, comprising a complex of an extract of Ashwagandha (Withania somnifera) and an extract of Siberian chrysanthemum (Chrysanthemum zawadskii Herbich var. latilobum (Maxim.) Kitamura) as an active ingredient.
The present invention relates to a composition for preventing, improving or treating obesity, comprising a complex of an extract of Ashwagandha (Withania somnifera) and an extract of Siberian chrysanthemum (Chrysanthemum zawadskii Herbich var. latilobum (Maxim.) Kitamura) as an active ingredient.
The complex provided from the present invention has very excellent effects of inhibiting differentiation of adipocytes, inhibiting lipid accumulation in adipocytes, and inhibiting pancreatic lipase, and thus it can be used in a pharmaceutical composition for preventing or treating obesity and a health functional food and food composition for preventing or improving obesity.
PHARMACEUTICAL COMPOSITION COMPRISING HL-NEUROPION (COMPLEX OF PINUS DENSIFLORA EXTRACT AND ALPINIA OFFICINARUM EXTRACT) AS ACTIVE INGREDIENT FOR IMPROVING COGNITIVE FUNCTION AND TREATING DEMENTIA THROUGH EXCELLENT ANTI-INFLAMMATORY EFFECT, INHIBITION OF NEUROTRANSMITTER DEGRADATION, AND INHIBITION OF AMYLOID BETA AGGREGATION
The present invention relates to: a health functional food, food product, or therapeutic pharmaceutical composition for preventing or ameliorating dementia and cognitive decline, wherein a complex of a Pinus densiflora extract and an Alpinia officinarum extract is included as an active ingredient; and a method for producing same. The complex provided by the present invention was not only found to have excellent acetylcholinesterase inhibitory activity and nitric oxide production inhibitory activity, but was also found to have an activity of improving cognitive decline induced by beta amyloid administration in an animal model, and can thus be used as a health functional food and pharmaceutical for preventing, ameliorating, or treating dementia and cognitive decline.
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
4.
COMPOSITION FOR ANTI-AGING AND SKIN IMPROVEMENT, COMPRISING COMPLEX OF INDIAN GOOSE-BERRY EXTRACT AND BARLEY SPROUT EXTRACT (lB COMPLEX) AS ACTIVE INGREDIENT
The present invention relates to a health functional food, a food and a cosmetic composition for anti-oxidation, wrinkle improvement, elasticity improvement and skin moisturizing comprising a complex of an Indian gooseberry (Phyllanthus emblica) extract and a barley sprout (Hordeum vulgare) as an active ingredient. The complex provided from the present invention has excellent DPPH scavenging activity, elastase inhibitory activity, MMP-1 inhibitory activity and hyaluronic acid content increasing effect, so it can be used as a health functional food, a food and a cosmetic composition for anti-oxidation, wrinkle improvement, elasticity improvement and skin moisturizing.
COMPOSITION FOR ENHANCING EXERCISE PERFORMANCE, COMPRISING, AS ACTIVE INGREDIENT, COMPLEX OF WITHANIA SOMNIFERA EXTRACT AND CHRYSANTHEMUM ZAWADSKII HERBICH VAR. LATILOBUM (MAXIM.) KITAMURA EXTRACT (ASC COMPLEX)
Withania somniferaChrysanthemum zawadskii Herbich var. latilobum (Maxim.) KitamuraChrysanthemum zawadskii Herbich var. latilobum (Maxim.) Kitamura extract. The complex provided in the present invention has very excellent creatine kinase (CK) inhibitory activity and effects of reducing lactic acid production and increasing glycogen production in muscle cells, and thus can be used as a health functional food and a food composition for enhancing exercise performance.
A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
6.
COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING OBESITY, COMPRISING, AS ACTIVE INGREDIENT, COMPLEX (ASC COMPLEX) OF WITHANIA SOMNIFERA EXTRACT AND SIBERIAN CHRYSANTHEMUM EXTRACT
Withania somniferaChrysanthemum zawadskii Herbich var. latilobum (Maxim.) KitamuraChrysanthemum zawadskii Herbich var. latilobum (Maxim.) Kitamura extract. The complex provided in the present invention has the excellent effects of inhibiting adipocyte differentiation, inhibiting lipid accumulation in adipocytes, and having pancreatic lipase inhibition activity, and thus can be used as a pharmaceutical composition for preventing or treating obesity and as a health functional food and a food composition for preventing or alleviating obesity.
According to an embodiment of the present disclosure, provided is a hair dyeing composition comprising a phytophenol black complex which essentially comprises gallic acid and protocatechuic aldehyde, potassium alum, and an iron metal salt. When a combination of the phytophenol black complex, potassium alum, and an iron metal salt is used, high dyeing power is obtained, hair dyeing is possible within a short time while being safe to the human body, and various color can be realized on the hair according to the mixing weight ratio of the phytophenol black complex.
A61K 8/368 - Carboxylic acidsSalts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
A61K 8/19 - Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
A61K 8/58 - Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
A61Q 5/06 - Preparations for styling the hair, e.g. by temporary shaping or colouring
A61Q 5/10 - Preparations for permanently dyeing the hair
8.
COMPOSITION FOR ANTI-AGING AND SKIN IMPROVEMENT, COMPRISING COMPLEX OF INDIAN GOOSEBERRY EXTRACT AND BARLEY SPROUT EXTRACT (IB COMPLEX) AS ACTIVE INGREDIENT
Phyllanthus emblicaHordeum vulgareHordeum vulgare) sprout extract as an active ingredient. The complex provided from the present invention exhibits very excellent DPPH scavenging activity, elastase inhibition activity, MMP-1 inhibition activity, and a hyaluronic acid increasing effect and thus may be used for a health functional food, a food, and a cosmetic composition, for antioxidation for skin anti-aging, wrinkle reduction, elasticity improvement, and skin moisturization.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Nutraceuticals for use as a dietary supplement; Nutraceuticals for detoxifying the body, promoting brain health, energy production, cellular health and, immunity health, and for treatment of diabetes, gout, respiratory tract inflammation, and asthma; Food supplements; Protein dietary supplements; Dietetic food supplement; Mineral food supplements; Dietary supplements with a cosmetic effect; Health food supplements made principally of vitamins; Dietary supplements; Dietetic foods adapted for medical purposes; Dietary and nutritionally fortified food products in the nature of supplements adapted for medical purposes; Medicated food supplements for detoxifying the body, promoting brain health, energy production, cellular health and, immunity health, and for treatment of diabetes, gout, respiratory tract inflammation, and asthma; Dietary supplements for medical use; Food supplements for medical purposes; Pharmaceutical preparations for immune modulation and tissue regeneration; Medicines for human purposes, namely, medicines for immune modulation and tissue regeneration; Diet capsules; Vitamin preparations; Dietary and nutritional supplements; Nutritional supplements in the form of capsules, tablets, caplets, powder, syrups, gummies, gels; Detergents for medical purposes
Promoting the goods and services of others by means of operating an on-line comprehensive shopping mall with links to the retail web sites of others; import-export agency services; computerized on-line retail store services in the field of cosmetics; computerized on-line retail store services in the field of food supplements; computerized on-line retail store services in the field of dietary supplement drinks; computerized on-line retail store services in the field of dietary and nutritional supplements; computerized on-line retail store services in the field of nutraceutical for use as a dietary supplement; retail store services in relation to cosmetics; retail store services in relation to food supplements; retail store services in relation to dietary supplement drinks; retail store services in relation to dietary and nutritional supplements; retail store services in relation to nutraceutical for use as a dietary supplement; on-line wholesale and retail store services featuring cosmetics; on-line wholesale and retail store services featuring dietary supplement drinks; on-line wholesale and retail store services featuring food supplements; on-line wholesale and retail store services featuring dietary and nutritional supplements; on-line wholesale and retail store services featuring nutraceutical for use as a dietary supplement; retail store services featuring a wide variety of consumer goods of others; subscription-based online retail store services in the field of cosmetics; subscription-based online retail store services in the field of food supplements; subscription-based online retail store services in the field of dietary and nutritional supplements; subscription-based online retail store services in the field of nutraceutical for use as a dietary supplement
11.
Composition for preventing, alleviating or treating metabolic syndrome accompanied by obesity and/or diabetes, containing, as active ingredient, complex (IB complex) of Indian gooseberry extract and sprout barley extract
The present invention relates to a composition for prevention, improvement or treatment of metabolic syndrome comprising a complex of Indian gooseberry (amla) extract and barley sprout extract as an active ingredient. Specifically, the complex of Indian gooseberry extract and barley sprout extract reduces a body weight, blood sugar, insulin in blood and glycated hemoglobin in blood, and thereby it shows a synergistic effect in improvement of obesity or diabetes, and therefore it can be used as a pharmaceutical composition or health functional food for prevention or treatment of metabolic syndrome such as obesity and diabetes.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Health food supplements, namely, health food supplements based on plant extracts; health food supplements, namely, health food supplements based on squalene extracted from deep sea shark liver oil; health food supplements, namely, health food supplements based on squalene extracted from fish and shellfish; health food supplements, namely, health food supplements based on chitosan extracted from fish and shellfish; health food supplements, namely, health food supplements based on fish extracts; health food supplements, namely, health food supplements based on lactic acid bacteria; health food supplements, namely, health food supplements based on seaweed extracts; health food supplements, namely, health food supplements based on herbal extracts; health food supplements, namely, health food supplements based on red ginseng extracts; health food supplements, namely, health food supplements based on chitosan extracted from crayfish shells; health food supplements, namely, health food supplements based on chitosan extracted from crustacean; health food supplements, namely, health food supplements based on chitosan extracted from crab shells; health food supplements, namely, health food supplements based on fruit extracts; health food supplements, namely, health food supplements based on deer antlers; health food supplements, namely, health food supplements based on milk thistle extracts; health food supplements, namely, health food supplements based on mushroom extracts; health food supplements, namely, health food supplements based on squalene extracted from shark liver; health food supplements, namely, health food supplements based on shark cartilage extracts; health food supplements, namely, health food supplements based on cartilage extracts from shark fins; health food supplements, namely, health food supplements based on chitosan extracted from shrimp shells
13.
COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING METABOLIC SYNDROME ACCOMPANIED BY OBESITY AND/OR DIABETES, CONTAINING, AS ACTIVE INGREDIENT, COMPLEX (IB COMPLEX) OF INDIAN GOOSEBERRY EXTRACT AND SPROUT BARLEY EXTRACT
The present invention relates to a composition for preventing, alleviating or treating metabolic syndrome, containing, as an active ingredient, a complex of an Indian gooseberry (amla) extract and a sprout barley extract. Particularly, a complex of Indian gooseberry extract and a sprout barley extract, according to the present invention, exhibits a synergistic effect in the alleviation of obesity or diabetes by reducing body weight, blood sugar, blood insulin, and blood glycated hemoglobin, and thus can be used as a pharmaceutical composition or a health functional food for preventing or treating metabolic syndrome such as obesity and diabetes.
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
14.
Method for alleviating osteoarthritis by using composite (HL-Joint 100) of achyranthes bidentata, eucommin ulmoides oliver and pomegranate extracts, which has antiinflammatory effect caused by COX2 and PGE2 inhibition, cartilage protective effect caused by MMP-2 and -9 inhibition and cartilage regeneration effect caused by increase in type II collagen synthesis
The present invention relates to a composition for preventing and treating osteoarthritis, which contains a pomegranate concentrate, a eucommia bark extract and an achyranthis radix extract as active ingredients. More specifically, the composite composition of a pomegranate concentrate, a eucommia bark extract and an achyranthis radix extract according to the present invention has a synergistic effect of improving osteoarthritis. In particular, because it can directly protect and regenerate the cartilage and can improve joint stiffness, it can be used in health food, etc.
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A61K 36/21 - Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
A61K 36/46 - Eucommiaceae (Eucommia family), e.g. hardy rubber tree
A61K 31/7032 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyl-diacylglycerides, lactobionic acid, gangliosides
A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
A61K 31/366 - Lactones having six-membered rings, e.g. delta-lactones
A61P 19/02 - Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
15.
Method for improving gingivitis and periodontitis by antibacterial, antioxidant and anti-inflammatory effects and inhibition of alveolar bone loss of complex extracts of moringa leaf and eucommia bark
eucommia bark extract according to the present invention provides a synergistic effect in improvement of a periodontal disease including gingivitis and periodontitis. Especially, it exhibits an effect of directly preventing or improving a periodontal disease through antioxidant, antibacterial or anti-inflammatory effect, improvement of alveolar bone loss and regeneration of alveolar bone, etc. Accordingly, it can be usefully used as a food, a medicine, a quasi-drug, etc.
A61K 36/46 - Eucommiaceae (Eucommia family), e.g. hardy rubber tree
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 1/02 - Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
16.
METHOD FOR ALLEVIATING GINGIVITIS AND PERIODONTITIS BY ANTIBIOSIS, ANTIOXIDATION, ANTI-INFLAMMATION, SUPPRESSION OF PERIODONTAL BONE LOSS, AND REGENERATION OF PERIODONTAL BONE OF COMPLEX OF MORINGA OLEIFERA LEAF EXTRACT AND EUCOMMIA ULMOIDES EXTRACT
The present invention relates to a composition containing a Moringa oleifera extract and a Eucommia ulmoides extract as active ingredients for prevention, alleviation, or treatment of periodontal diseases. More specifically, a complex composition of a Moringa oleifera extract and an Eucommia ulmoides extract, according to the present invention, is considered to have a synergistic effect on the alleviation of periodontal diseases including gingivitis and periodontitis, and particularly, exerts direct protection and alleviation effects on periodontal diseases, for example, antioxidation, antibiosis, anti-inflammation, alleviation, or suppression of periodontal bone loss and regeneration of periodontal bone, and thus has an advantage of a high utilization for food, medicines, quasi-drugs, and the like.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Health food supplements, mainly based on plant extracts;
health food supplements, mainly based on squalene extracted
from deep sea shark liver oil; health food supplements,
mainly based on squalene extracted from fish and shellfish;
health food supplements, mainly based on chitosan extracted
from fish and shellfish; health food supplements, mainly
based on fish extracts; health food supplements, mainly
based on lactic acid bacteria; health food supplements,
mainly based on seaweed extracts; health food supplements,
mainly based on herbal extracts; health food supplements,
mainly based on red ginseng extracts; health food
supplements, mainly based on chitosan extracted from
crayfish shells; health food supplements, mainly based on
chitosan extracted from crustacean; health food supplements,
mainly based on chitosan extracted from crab shells; health
food supplements, mainly based on fruit extracts; health
food supplements, mainly based on deer antlers; health food
supplements, mainly based on milk thistle extracts; health
food supplements, mainly based on mushroom extracts; health
food supplements, mainly based on squalene extracted from
shark liver; health food supplements, mainly based on shark
cartilage extracts; health food supplements, mainly based on
cartilage extracts from shark fins; health food supplements,
mainly based on chitosan extracted from shrimp shells.
18.
Composition for improving skin, containing pomegranate concentrate as active ingredient
The present disclosure relates to an effect of promoting hyaluronic acid synthesis of a pomegranate concentrate. A pomegranate concentrate, prepared by treating pomegranate with a starch-degrading enzyme and passing the same through a heating concentration process and having an ellagic acid content of 0.8 mg/g or higher and a polyphenol content of 8 mg/g or higher, has an effect of promoting hyaluronic acid. According to the present disclosure, hyaluronic acid synthesis can be promoted and skin moisturization can be improved by administering a food or pharmaceutical composition containing the pomegranate concentrate as an active ingredient to a subject in need of promotion of hyaluronic acid synthesis.
A61K 47/00 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient
A61Q 19/02 - Preparations for care of the skin for chemically bleaching or whitening the skin
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
C07C 39/12 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
A61K 8/49 - Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
METHOD FOR ALLEVIATING OSTEOARTHRITIS BY USING COMPOSITE (P-JOINT 100) OF ACHYRANTHES BIDENTATA, EUCOMMIN ULMOIDES OLIVER AND POMEGRANATE EXTRACTS, WHICH HAS ANTIINFLAMMATORY EFFECT CAUSED BY COX2 AND PEG2 INHIBITION, CARTILAGE PROTECTIVE EFFECT CAUSED BY MMP-2 AND -9 INHIBITION AND CARTILAGE REGENERATION EFFECT CAUSED BY INCREASE IN TYPE II COLLAGEN SYNTHESIS
The present invention relates to a composition for preventing and alleviating osteoarthritis, containing a pomegranate concentrate, a Eucommia ulmoides OLIVER extract and an Achyranthes bidentata extract as active ingredients. More specifically, according to the present invention, the composite composition of a pomegranate concentrate, a Eucommia ulmoides OLIVER extract and an Achyranthes bidentata extract is considered to have a synergistic effect on osteoarthritis alleviation and, particularly, exhibits direct protective and alleviatory effects on a joint, such as cartilage protection, cartilage regeneration or joint stiffness alleviation, thereby having high utilization as a dietary supplement and the like.
The present invention relates to a pomegranate extract and a composition containing the same, wherein 1.8-3.2 mg of ellagic acid is contained on the basis of per gram unit of the total weight of the pomegranate extract, and thus there is an excellent effect of alleviating women's menopausal symptoms even with a small daily administration amount of the pomegranate extract. In addition, according to the present invention, there is an advantage of enabling the extract to be administered to a polyphenol-sensitive individual.
The present invention relates to an effect of promoting hyaluronic acid synthesis of a pomegranate concentrate, and is characterized in that the pomegranate concentrate, prepared by treating pomegranate with a starch degrading enzyme and making the same pass through a heating-concentration process and having ellagic acid content of 0.8 mg/g or greater and polyphenol content of 8 mg/g or greater, has the effect of promoting hyaluronic acid synthesis. According to the present invention, hyaluronic acid synthesis can be promoted by administering a food or pharmaceutical composition containing the pomegranate concentrate as an active ingredient to a subject in need of the promotion of hyaluronic acid synthesis, and skin moisturization can be improved.
The present invention relates to: a natural composition containing a composite extract of pomegranates and red clover, exhibiting synergistic effects with respect to a menopausal symptom alleviation effect, an estrogen-like effect, an anti-obesity effect, a hyperlipidemia inhibitory effect, a fatty liver protective effect, an osteoporosis inhibitory effect and the like without any side effects; and various uses thereof, in particular, pharmaceutical, bromatological and cosmetic uses.
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
A pomegranate pulp extract is disclosed. The pomegranate pulp extract is effective in relieving women's menopausal symptoms, anxiety disorders, depression or attention deficit disorders due to the presence of a large amount of ellagic acid. Further disclosed is a method for further improving the relieving effect of the pomegranate extract on women's menopausal symptoms, anxiety disorders, depression or attention deficit disorders. The method includes increasing the content of ellagic acid in the pomegranate extract.
