The present invention provides a patch for relieving lumbago, the patch comprising a backing and an adhesive layer laminated on the backing, wherein the adhesive layer comprises an adhesive base and 0.70 to 1.50 mg of diclofenac sodium per cm2 of application area, and the patch is used by applying the patch once a day to the chest region, the abdominal region, the dorsal region, the brachial region, or the femoral region of a human.
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations for the treatment and prevention of excessive perspiration; pharmaceutical preparations for use in treating hand perspiration; pharmaceutical preparations for use in treating foot perspiration; pharmaceutical preparations for the treatment of maschalephidrosis; pharmaceutical preparations namely, topical treatments for hyperhidrosis
This applicator is for applying a microneedle device to the skin and comprises: a body having a bottom part that comes into contact with the skin, a top part facing the bottom part, and a side part extending along the height direction from the bottom part toward the top part; a switch having an arm attached to the side part so as to extend along the lateral direction from the side part toward the center of the body, and a piston provided at a free end of the arm and to be pushed to the skin by a user; and at least a recovery mechanism that holds the microneedle device when the microneedle device is applied to the skin by the user's operation of the switch.
An application kit according to the present invention includes an applicator and a stage. The applicator comprises: a body which has a bottom part that contacts the skin, a top part that opposes the bottom part, and a side part that extends along the height direction from the bottom part toward the top part; a switch which has an arm that is attached to the side part so as to extend along a lateral direction from the side part toward the center of the body, and a piston that is provided at a free end of the arm; and a stopper which supports a microneedle device disposed inside the body so as to be positioned between the piston and the skin. The stage includes a columnar part for supporting the microneedle device. The columnar part that supports the microneedle device is inserted into the body toward the piston, and in response thereto, the microneedle device enters between the piston and the stopper and is supported by the stopper.
An applicator according to the present invention comprises: a body having a bottom part that comes in contact with skin, a top part opposite from the bottom part, and a side part extending along a height direction oriented from the bottom part toward the top part; a switch having an arm attached to the side part so as to extend along a lateral direction oriented from the side part toward the center of the body, and a piston that is provided to the free end of the arm and is pressed in toward the skin by a user; a stopper for supporting a microneedle device arranged within the body so as to be positioned between the piston and the skin; and an eaves part provided so as to cover at least a part of a peripheral edge part of the microneedle device when the microneedle device supported by the stopper is viewed from the top-part side along the height direction. When the microneedle device moves toward the top part, the eaves part stops the movement of the microneedle device toward the top part.
This cataplasm includes a support layer, an adhesive layer laminated on the support layer, and a release liner provided on a surface of the adhesive layer which is on the opposite side from the support layer. The adhesive layer contains a drug, water, gelatin, l-menthol, a (methyl acrylate)-(2-ethylhexyl acrylate) copolymer resin emulsion, and magnesium aluminometasilicate, wherein the amount of the (methyl acrylate)-(2-ethylhexyl acrylate) copolymer resin emulsion is 1.5-20 mass%, the amount of magnesium aluminometasilicate is 0.25-0.45 mass%, and the amount of gelatin is 1-3 mass% relative to the whole mass of the adhesive layer.
Disclosed is a method for relieving cancer pain in a patient. The method comprises administering a patch to a patient in need thereof, wherein the patch comprises a backing layer and an adhesive layer laminated on the backing layer, the adhesive layer comprises an adhesive base and 150 mg to 225 mg of diclofenac sodium, and wherein the patch is applied once a day.
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
This applicator is for applying a microneedle device to the skin and comprises: a body having a bottom part that comes into contact with the skin, a top part facing the bottom part, and a side part extending along the height direction from the bottom part toward the top part; a switch having an arm attached to the side part so as to extend along the lateral direction from the side part toward the center of the body, and a piston provided at a free end of the arm and to be pushed to the skin by a user; and at least one stopper that supports the microneedle device disposed in the body so as to be positioned between the piston and the skin.
A microneedle sheet includes: a sheet body having a main surface; one or more microneedles formed in the sheet body, each microneedle having a tip end; and an X-shaped cut formed in vicinity of the tip end of at least one microneedle among the one or more microneedles.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Transdermal patches and plasters featuring analgesic and anti-inflammatory preparations; analgesic preparations; anti-inflammatory preparations; transdermal patches for use in the treatment of pain; pharmaceutical preparations for the relief of aches and pains.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Transdermal patches and plasters featuring analgesic and anti-inflammatory preparations; analgesic preparations; anti-inflammatory preparations; transdermal patches for use in the treatment of pain; pharmaceutical preparations for the relief of aches and pains.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceuticals, medical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic food and substances adapted for medical or veterinary use, food for babies; Dietary supplements for human beings and animals; Plasters, materials for dressings; materials for stopping teeth; dental wax; Disinfectants; Preparations for destroying vermin; Fungicides, herbicides; medicated gels; medicated creams; medicated lotions; medicated sprays; medicated adhesive plasters; medicated poultices; medicated oils; medicated liniments; medicated ointments; medicated patches; medicated pads; medicated foam; medicated tablets; gauze for dressing; bandages for dressings; adhesive plasters; transdermal anti-inflammatory analgesic pharmaceuticals; cooling sprays for medical purposes.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceuticals, medical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic food and substances adapted for medical or veterinary use, food for babies; Dietary supplements for human beings and animals; Plasters, materials for dressings; materials for stopping teeth; dental wax; Disinfectants; Preparations for destroying vermin; Fungicides, herbicides; medicated gels; medicated creams; medicated lotions; medicated sprays; medicated adhesive plasters; medicated poultices; medicated oils; medicated liniments; medicated ointments; medicated patches; medicated pads; medicated foam; medicated tablets; gauze for dressing; bandages for dressings; adhesive plasters; transdermal anti-inflammatory analgesic pharmaceuticals; cooling sprays for medical purposes.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceuticals, medical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic food and substances adapted for medical or veterinary use, food for babies; Dietary supplements for human beings and animals; Plasters, materials for dressings; materials for stopping teeth; dental wax; Disinfectants; Preparations for destroying vermin; Fungicides, herbicides; medicated gels; medicated creams; medicated lotions; medicated sprays; medicated adhesive plasters; medicated poultices; medicated oils; medicated liniments; medicated ointments; medicated patches; medicated pads; medicated foam; medicated tablets; gauze for dressing; bandages for dressings; adhesive plasters; transdermal anti-inflammatory analgesic pharmaceuticals; cooling sprays for medical purposes.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Absorbent cotton; adhesive bandages; adhesive bandages for skin wounds; adhesive plasters; adhesive plasters for medical purposes; analgesics; anti-inflammatories; breast-nursing pads; cotton swabs for medical purposes; cotton wool for medical purposes; dental cements; dental wax; dietary supplements for general health and well-being; dressings, medical; ear bandages; empty capsules for pharmaceuticals; eye patches for medical purposes; gauze for dressings; materials for artificial teeth; materials for dental fillings; medical plasters; medical sprays comprised of water and alcohol in an atomized container used to produce a cooling effect; menstruation bandages; menstruation tampons; sanitary napkins; sanitary panties; surgical adhesives; veneer for prosthetic dentistry
(2) Medicated transdermal patches, plasters, pads, poultices, gels, creams, liquid, and sprays for the relief of aches and pains.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Medicated transdermal patches, plasters, pads, poultices and creams for the relief of aches and pains; Patches, plasters, pads, poultices and medicated creams for the treatment of musculoskeletal system, namely, connective tissue diseases, bone diseases, spinal diseases, spinal neuropathies, back pain, fractures, sprains, and cartilage injuries, osteoarthritis, arthritis, humeral epicondylitis, tendonitis, myalgia and inflammation and pain; Antiphlogistic and analgesic spray for the temporary relief of minor muscular aches and pains; Analgesic gels; Antiphlogistic and analgesic gel for the temporary relief of minor muscular aches and pains; Gauze for dressing; Adhesive plasters, adhesive bandages, adhesive dressings, surgical adhesives, medical plasters
(2) Absorbent cotton; analgesics; anti-inflammatories; breast-nursing pads; cotton swabs for medical purposes; dental cements; dental wax; dressings, medical; ear bandages; empty capsules for pharmaceuticals; eye patches for medical purposes; materials for artificial teeth; menstruation bandages; menstruation tampons; sanitary napkins; sanitary panties; topical analgesics
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceuticals, medical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic food and substances adapted for medical or veterinary use, food for babies; Dietary supplements for human beings and animals; Plasters, materials for dressings; Material for stopping teeth, dental wax; Disinfectants; Preparations for destroying vermin; Fungicides, herbicides; Medicated gels; Medicated creams; Medicated lotions; Medicated sprays; Medicated adhesive plasters; Medicated poultices; Medicated oils; Medicated liniments; Medicated ointments; Medicated patches; Medicated pads; Medicated foam; Medicated tablets; Gauze for dressing; Bandages for dressings; Adhesive plasters; Transdermal anti-inflammatory analgesic pharmaceuticals; Cooling sprays for medical purposes.
A rotigotine-containing patch including a backing layer and an adhesive agent layer, wherein the adhesive agent layer comprises at least one selected from the group consisting of rotigotine and a pharmaceutically acceptable salt of rotigotine, and
the adhesive agent layer further comprises an adhesive base agent, and at least one selected from the group consisting of thioglycolic acid and a pharmaceutically acceptable salt of thioglycolic acid.
A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
The present invention relates to a poultice including: a backing layer; and an adhesive agent layer, wherein the adhesive agent layer comprises at least one selected from the group consisting of carboxymethyl cellulose and pharmaceutically acceptable salts thereof; a silicic anhydride; a drug; and a water-soluble polymer; and a particle diameter D50 at which a cumulative volume in a particle size distribution of the silicic anhydride becomes 50% is 0.2 to 9.0 μm.
The present invention aims to manufacture a microneedle device capable of carrying and administering a larger amount of biologically active substance per one microneedle. One aspect of the present invention is a method of manufacturing a microneedle device comprising coating microneedles with a coating liquid, wherein the coating liquid comprises a biologically active substance and a sulfated polysaccharide. The microneedle device manufactured by such a method comprises a substrate, microneedles disposed on the substrate, and a coating formed on the microneedles, wherein the coating comprises a biologically active substance and a sulfated polysaccharide.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations; pharmaceutical preparations for
human use; pharmaceutical preparations for animals;
medicinal drinks; vitamin preparations; fungicides;
parasiticides; preparations for destroying vermin; insect
repellents; herbicides; nutritional supplements; powdered
nutritional supplement drink mix; nutritional supplement
beverages; nutritional supplement drinks for medical
purposes; nutritional supplements in tablet form for medical
purposes; tonics [medicines]; tonics for medical purposes;
reagent paper for medical purposes; oiled paper for medical
purposes; adhesive tapes for medical purposes; drug delivery
agents in the form of edible wafers for wrapping powdered
pharmaceuticals; gauze for dressings; capsules for
medicines; eyepatches for medical purposes; ear bandages;
sanitary pads; sanitary tampons; sanitary napkins; sanitary
panties; absorbent cotton; sticking plasters; bandages for
dressings; antiseptic liquid bandages; breast-nursing pads;
cotton sticks for medical purposes; dental materials for
stopping the teeth; dental wax; composite materials for
dental purposes; diapers for incontinence; diaper covers;
surgical implants comprised of living tissues; fly catching
paper; mothproofing paper; lacteal flour for babies; dietary
supplements for human beings; dietary supplement drinks;
dietary supplement drink mixes; dietetic beverages adapted
for medical purposes; dietetic foods adapted for medical
purposes; beverages for babies; food for babies; dietary
supplements for animals; semen for artificial insemination;
medicated mouth care preparations.
A microneedle patch according to one example includes a backing, an adhesive layer provided on the main surface of the backing, and a microneedle array at least a part of which is positioned within the adhesive layer, wherein the adhesive layer includes a water-soluble polymer and water, and a loss tangent of the adhesive layer under measurement conditions of an environmental temperature of 25° C. and a frequency of 1 Hz is 0.20 to 0.41.
Disclosed is a patch comprising an adhesive layer on a backing layer, wherein the adhesive layer comprises lidocaine or a pharmaceutically acceptable salt thereof, propylene glycol, a rubber adhesive base and a terpene resin, wherein the content of the lidocaine or pharmaceutically acceptable salt thereof in the adhesive layer is 3 mass % to 5 mass % with respect to the total mass of the adhesive layer, the content of the terpene resin in the adhesive layer is 5 mass % to 18 mass % with respect to the total mass of the adhesive layer, and the content of propylene glycol in the adhesive layer is 3 mass % to 7 mass % with respect to the total mass of the adhesive layer, wherein crystals are not precipitated in the patch, and wherein the adhesive layer has an adhesive surface, and requires a force of 1.3 N or less to release the adhesive surfaces during self-adhesion.
A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
The patch of the present invention comprises a backing layer and an adhesive layer laminated on the backing layer, wherein a water vapor transmission rate of the backing layer is 400 g/m2·24 hours or more, and the adhesive layer comprises a drug, dimethylsulfoxide and an adhesive. Such a patch does not fall off easily even after long wear.
A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A61K 31/405 - Indole-alkanecarboxylic acidsDerivatives thereof, e.g. tryptophan, indomethacin
A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
Provided is a poultice comprising a support layer, an adhesive layer, and a liner layer for protecting the adhesive layer, wherein the adhesive layer contains water, a water-soluble polymer, a crosslinking agent, and a surfactant. In the poultice, the crosslinking agent is magnesium aluminometasilicate and the content thereof is 0.25-2.5 mass% with respect to the total mass of the adhesive layer, and the surfactant is polyethylene glycol monostearate and the content thereof is 0.8-4.5 mass% with respect to the total mass of the adhesive layer.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Medicated transdermal patches for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal plasters for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal cataplasms for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal gels for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal creams for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal liquid for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal sprays for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; medical sprays comprised of water and alcohol in an atomized container used to produce a cooling effect
(2) Absorbent cotton; adhesive bandages; adhesive bandages for skin wounds; adhesive plasters; adhesive plasters for medical purposes; analgesics; anti-inflammatory preparations; bandages for dressings; breast-nursing pads; cotton sticks for medical purposes; cotton swabs for medical purposes; cotton wool for medical purposes; dental cements; dental wax; dietary supplements for general health and well-being; ear bandages; empty capsules for pharmaceuticals; eye patches for medical purposes; gauze for dressings; materials for artificial teeth; materials for dental fillings; medical plasters; menstruation bandages; menstruation tampons; sanitary napkins; sanitary panties; surgical adhesives; veneer for prosthetic dentistry
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Medicinal drinks; Vitamin preparations; Dietary supplements; Dietary supplemental drinks; Dietary supplement drinks for medical purposes; Nutritional supplements; Beverages containing taurine and vitamins for use as a nutritional supplement; Powdered nutritional supplement drink mix; Dietetic beverages adapted for medical purposes; Dietetic beverages, namely, energy drinks adapted for medical purposes; Vitamin fortified beverages for medical purposes; Dietetic food adapted for medical purposes.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and other preparations for
destroying vermin, fungicides, herbicides; reagent paper for
medical purposes; oiled paper for medical purposes; adhesive
tapes for medical purposes; drug delivery agents in the form
of edible wafers for wrapping powdered pharmaceuticals;
gauze for dressings; empty capsules for pharmaceuticals;
eyepatches for medical purposes; ear bandages; menstruation
bandages; menstruation tampons; sanitary napkins; sanitary
panties; absorbent cotton; adhesive plasters; bandages for
dressings; liquid bandages; breast-nursing pads; cotton
swabs for medical use; dental materials; diapers; diaper
covers; surgical implants comprised of living tissues; fly
catching paper; mothproofing paper; lacteal flour for
babies; dietary supplements for human beings; dietetic
beverages adapted for medical purposes; dietetic foods
adapted for medical purposes; beverages for babies; food for
babies; dietary supplements for animals; semen for
artificial insemination; medicines for human purposes;
adhesive skin patches for medical purposes; febrifuges;
balms for medical purposes; Chinese traditional medicinal
herbs; analgesics; cooling sprays for medical purposes;
radioactive substances for medical purposes; oxygen for
medical purposes; chemical conductors for electrocardiograph
electrodes; disinfectants; contact lens solutions;
bacteriological culture mediums for medical purposes or
veterinary purposes; dietetic preparations adapted for
medical purposes; nutritional supplements; depuratives;
medicines for veterinary purposes; preparations for
destroying vermin; tissues impregnated with pharmaceutical
lotions; scapulars for surgical purposes; moleskin for
medical purposes; cotton for medical purposes; medical
dressings; teeth filling material.
An adhesive patch with a cover material includes an adhesive patch part including a backing and a drug layer formed on the backing; and a cover part including a cover layer and a cover adhesive layer formed on the cover layer, and the cover adhesive layer is attached to the backing to cover the adhesive patch part. The cover layer is formed of a non-woven fabric, and has an elongation rate of 50% to 300% in a flow direction and a width direction. The cover adhesive layer is made of a rubber-based adhesive in which a main adhesive base is a rubber-based adhesive base, and has a loss tangent (tanδ) of 0.7 to 0.95 at 32° C. and 0.1 Hz.
(1) Chemically activated cold gel packs for medical purposes; chemically activated cold gel packs for therapeutic purposes; cooling patches for medical purposes; ice bags for medical purposes
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Medicated transdermal patches, plasters, cataplasms, gels, creams and sprays for the relief of aches and pains of muscles and joints; Anti-inflammatories; analgesics; Gauze for medical purposes; gauze for dressings; Capsules sold empty for pharmaceuticals; Eyepatches for medical purposes; Ear bandages; Menstruation bandages; menstruation tampons, sanitary napkins; Absorbent cotton; Cotton wool for medical purposes; Adhesive plasters, namely, adhesive bandages, surgical adhesives, medical and surgical plasters, bandages for dressings, dressings for wounds, medical dressings, surgical and medical dressings, wadding for wound dressing, wound dressings, dressings for burns, sterile dressings; Breast-nursing pads, breast-nursing padding, breast pads; Cloth diapers, baby diapers, disposable diapers, incontinence diapers; Dietary supplements for general health and well being; dietetic beverages namely, nutritional supplement meal replacement beverages containing vitamins and minerals; nutraceutical beverages for general health and well being; energy drinks for general health and well being; nutritional supplements in liquid form for boosting energy; Antihistamines; decongestants; Pharmaceutical preparations for the treatment of central nervous system diseases; Pharmaceutical preparations for the treatment of Parkinson's disease; Transdermal patches for use in the treatment of central nervous system diseases and disorders; Transdermal patches for use in the treatment of Parkinson's disease.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations for the treatment of central nervous system diseases and disorders; pharmaceutical preparations for the treatment of Parkinson's disease; transdermal patches for use in the treatment of central nervous system diseases and disorders; transdermal patches for use in the treatment of Parkinson's disease.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Medicated transdermal patches, plasters, pads and cataplasms for relief of the aches of rheumatoid arthritis, and the aches and pains of muscles, joints and tendons; anti-inflammatory and analgesic agents; other pharmaceuticals in the form of patches, plasters, pads, cataplasms, creams and gels for use in the treatment of lumbago, namely, muscular and fascial lumbago, spondylosis deformans discopathy, and sprain of lumbar spine, osteoarthiritis, humeroscapular periarthritis, tendinitis, tendo-vaginitis, peritendinitis, humeral epicondylitis, tennis elbow, myalgia and post-traumatic swelling and pain; medicated transdermal patches to treat cancer pain; adhesive plasters for medical use; bandages for dressings.
39.
METHOD FOR INHIBITING GENERATION OF DICLOFENAC INDOLINONES
A method for inhibiting the generation of diclofenac indolinones in an adhesive patch is provided. This adhesive patch comprises a support body layer and an adhesive layer that is layered on the support body layer. The aforementioned method includes a step for mixing a diclofenac free acid and an adhesive base to acquire an adhesive composition, and a step for shaping the adhesive composition to obtain an adhesive patch. The content of the diclofenac free acid is 0.5-8 mass % on the basis of the total mass of the adhesive layer.
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A microneedle patch according to the present invention comprises: a support body; an adhesive layer provided on the main surface of the support body; and a microneedle array having at least a portion positioned inside the adhesive layer. The adhesive layer contains a water-soluble polymer, glycerin, and water. The water content is 45-70 mass% with respect to the total mass of the adhesive layer. The microneedle array comprises a substrate and at least one microneedle rising up from the main surface of the substrate. The adhesive layer includes a main portion positioned on the microneedle array. The thickness of the main portion is 0.9-1.3 times the length of the microneedle.
A microneedle sheet according to one embodiment includes: a sheet body having a main surface; and at least one microneedle formed on the sheet body and lying along the main surface. Each of the at least one microneedle has a base positioned on a first side of the sheet body and a tip oriented toward a second side of the sheet body that is opposite to the first side. A first portion of the sheet body is bent from the first side, whereby the microneedle positioned in the first portion is raised from the main surface and the raised microneedle is applied to skin.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Soft drinks; Soft drinks, non-carbonated; Soft drinks containing vitamins; Energy drinks; Energy drinks enhanced with taurine and vitamins; Sports drinks; Sports drinks enhanced with taurine and vitamins Medicinal drinks; Vitamin preparations; Dietary supplements; Dietary supplemental drinks; Dietary supplement drinks for medical purposes; Nutritional supplements; Beverages containing taurine and vitamins for use as a nutritional supplement; Powdered nutritional supplement drink mix; Dietetic beverages adapted for medical purposes; Dietetic beverages, namely, energy drinks adapted for medical purposes; Vitamin fortified beverages for medical purposes; Dietetic food adapted for medical purposes
05 - Pharmaceutical, veterinary and sanitary products
32 - Beers; non-alcoholic beverages
Goods & Services
Pharmaceuticals, medical and veterinary preparations; sanitary preparations for medical purposes; dietetic food and substances adapted for medical or veterinary use, food for babies; dietary supplements for humans and animals; plasters, materials for dressings; material for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicides; medicated gels; medicated creams; medicated lotions; medicated sprays; medicated adhesive plasters; medicated poultices; medicated oils; medicated liniments; medicated ointments; medicated patches; medicated pads; medicated foam; medicated tablets; gauze for dressing; bandages for dressings; adhesive plasters; transdermal anti-inflammatory analgesic pharmaceuticals; cooling sprays for medical purposes; medicinal drinks; tonics [medicines]; vitamin preparations; nutritional supplements; dietary supplemental drinks; dietetic beverages adapted for medical purposes; dietary supplement drink mixes. Beers; non-alcoholic beverages; mineral and aerated waters; fruit beverages and fruit juices; syrups and other non-alcoholic preparations for making beverages; soft drinks; energy drinks; sports drinks; concentrates for use in the preparation of energy drinks; concentrates for use in the preparation of sports drinks; concentrates for use in the preparation of soft drinks; beverages containing vitamins.
44.
ROTIGOTINE-CONTAINING PATCH AND METHOD FOR IMPROVING STABILITY OF ROTIGOTINE
A rotigotine-containing patch that is provided with a support layer and an adhesive layer, wherein the adhesive layer contains at least one selected from the group consisting of rotigotine and a pharmaceutically acceptable salt thereof, together with an adhesive base and propyl gallate.
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61P 25/00 - Drugs for disorders of the nervous system
A diclofenac-containing patch package product, in which a diclofenac-containing patch, including an adhesive layer containing diclofenac sodium as a drug and dimethyl sulfoxide as a solvent, and a backing layer, is sealed in a packaging bag,
the packaging bag being formed of a laminate at least comprising:
an innermost layer composed of at least one selected from the group consisting of polyethylene terephthalate and cycloolefin polymer;
an oxygen barrier layer arranged outside the innermost layer; and
an outer layer arranged outside the oxygen barrier layer.
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
46.
Method for suppressing production of asenapine-N-oxide
The present invention provides a patch comprising an adhesive layer on a backing, the adhesive layer comprising: asenapine or a pharmaceutically acceptable salt thereof; an adhesive base; and at least one selected from the group consisting of thiosulfates, sulfites, and pyrosulfites.
A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
Disclosed is a transdermal patch for treating osteoarthritis. The transdermal patch comprises a support layer and an adhesive layer laminated on the support layer. The adhesive layer includes an adhesive base, diclofenac sodium, dimethyl sulfoxide, and an organic acid. The organic acid content is 6-8 mass % of the total mass of the adhesive layer. The transdermal patch is applied once daily to an affected part and the dosage of diclofenac sodium per application is 70-150 mg.
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A packaging bag according to one example includes: a bag body configured to store a plurality of folded patches; an opening formed in the bag body; and a flap label configured to cover the opening such that the opening is capable of being opened and closed. The opening is formed such that Lp/La is 1.5 to 2.5 and Lq/Lb is 1.8 to 2.8, where La denotes a first length of the opening along a first direction, Lp denotes a first length of the folded patch along the first direction, Lb denotes a second length of the opening along a second direction orthogonal to the first direction, the second length being shorter than the first length, and Lq denotes a second length of the folded patch along the second direction.
B65D 83/08 - Containers or packages with special means for dispensing contents for dispensing thin flat articles in succession
B65D 75/58 - Opening or contents-removing devices added or incorporated during package manufacture
B65D 85/62 - Containers, packaging elements or packages, specially adapted for particular articles or materials for stacks of articlesContainers, packaging elements or packages, specially adapted for particular articles or materials for special arrangements of groups of articles
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceuticals, medical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic food and substances adapted for medical or veterinary use, food for babies; Dietary supplements for human beings and animals; Plasters, materials for dressings; materials for stopping teeth; dental wax; Disinfectants; Preparations for destroying vermin; Fungicides, herbicides; medicated gels; medicated creams; medicated lotions; medicated sprays; medicated adhesive plasters; medicated poultices; medicated oils; medicated liniments; medicated ointments; medicated patches; medicated pads; medicated foam; medicated tablets; gauze for dressing; bandages for dressings; adhesive plasters; transdermal anti-inflammatory analgesic pharmaceuticals; cooling sprays for medical purposes; Adhesive sheet with deodorant, deodorizing and odor control effects; Air deodorizing preparations comprised of activated charcoal; Deodorants, other than for human being and for animals; Deodorizers, other than for human being and for animals; Odor neutralizing preparations, other than for human being and for animals; Air deodorizer; Room deodorizer; Household deodorizer; Deodorants for clothing or textiles; Odor neutralizing preparations for clothing and textiles; Deodorizers for shoes; Deodorizers for garbage disposals; Deodorizers for lining garbage bags and trash cans; Deodorizers for toilets; Deodorizers for litter trays; Deodorizers for kitchen; Deodorizers for refrigerators; Deodorizers for automobiles; All purpose deodorizing preparations for household, commercial or industrial use; Odor neutralizing preparations for general use on various surfaces.
Disclosed is a method for inhibiting degradation of asenapine or a pharmaceutically acceptable salt thereof in a patch. The patch comprises an adhesive layer on a base, and the adhesive layer contains an adhesive base and asenapine or a pharmaceutically acceptable salt thereof. The method includes incorporating at least one amine compound selected from the group consisting of monoethanolamine, diethanolamine, diisopropanolamine, isopropanolamine, triethanolamine and meglumine in the adhesive layer.
A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids
A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceuticals, medical and veterinary preparations; sanitary preparations for medical purposes; dietetic food and substances adapted for medical or veterinary use, food for babies; dietary supplements for humans and animals; plasters, materials for dressings; material for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicides; medicated gels; medicated creams; medicated lotions; medicated sprays; medicated adhesive plasters; medicated poultices; medicated oils; medicated liniments; medicated ointments; medicated patches; medicated pads; medicated foam; medicated tablets; gauze for dressing; bandages for dressings; adhesive plasters; transdermal anti-inflammatory analgesic pharmaceuticals; cooling sprays for medical purposes; pharmaceutical preparations for the treatment of central nervous system diseases and disorders; pharmaceutical preparations for the treatment of Parkinson’s disease.
Disclosed is a patch comprising an adhesive layer on a backing layer, wherein the adhesive layer comprises lidocaine or a pharmaceutically acceptable salt thereof, propylene glycol, a rubber adhesive base and a terpene resin, wherein the content of the lidocaine or a pharmaceutically acceptable salt thereof in the adhesive layer in terms of free form is 2 mass % to 6 mass % with respect to the total mass of the adhesive layer, wherein the ratio of the mass of the lidocaine or a pharmaceutically acceptable salt thereof in terms of free form to the mass of propylene glycol in the adhesive layer is 1:0.6 to 1:1.8, and wherein the content of the terpene resin in the adhesive layer is 5 mass % to 18 mass % with respect to a total mass of the adhesive layer.
A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
Disclosed is a patch in which degradation of asenapine or a pharmaceutically acceptable salt thereof is inhibited. The patch comprises an adhesive layer on a base, wherein the adhesive layer contains an adhesive base, asenapine or a pharmaceutically acceptable salt thereof, and at least one basic amino acid selected from the group consisting of lysine, arginine and histidine, or a pharmaceutically acceptable salt of said basic amino acid.
A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids
A packaging bag includes a cutting guide band extending along a transverse direction. The cutting guide band includes, a first guide band having first cut lines that are inclined at a predetermined angle with respect to the transverse direction; a second guide band having second cut lines that are inclined at a predetermined angle in a direction opposite a direction of the first cut lines with respect to the transverse direction; and a third guide band having third cut lines that are inclined at a predetermined angle in the same direction as the direction of the first cut lines with respect to the transverse direction. The cutting guide band has a fourth cut line between the first guide band and the second guide band and/or between the second guide band and the third guide band, the fourth cut line being perforated and extending along the transverse direction.
B65D 65/40 - Applications of laminates for particular packaging purposes
B65D 77/12 - Container closures formed after filling by collapsing and flattening the mouth portion of the container and securing without folding, e.g. by pressure-sensitive adhesive, heat-sealing, welding or applying separate securing members
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A rotigotine-containing adhesive patch which comprises a support layer and a pressure-sensitive adhesive layer, wherein the pressure-sensitive adhesive layer contains at least one compound selected from the group consisting of rotigotine and pharmacologically acceptable salts of rotigotine, characterized in that the pressure-sensitive adhesive layer further contains a pressure-sensitive adhesive base and at least one compound selected from the group consisting of thioglycolic acid and pharmacologically acceptable salts of thioglycolic acid.
A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61P 25/00 - Drugs for disorders of the nervous system
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Transdermal patches and plasters featuring analgesic and anti-inflammatory preparations; analgesic preparations; anti-inflammatory preparations; transdermal patches for use in the treatment of pain; pharmaceutical preparations for the relief of aches and pains
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Transdermal patches and plasters featuring analgesic and anti-inflammatory preparations; analgesic preparations; anti-inflammatory preparations; transdermal patches for use in the treatment of pain; pharmaceutical preparations for the relief of aches and pains
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
35 - Advertising and business services
Goods & Services
Non-medicated cosmetics and toiletry preparations; non-medicated dentifrices; perfumery, essential oils; bleaching preparations and other substances for laundry use; cleaning, polishing, scouring and abrasive preparations; deodorants for personal use. Pharmaceuticals, medical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic food and substances adapted for medical or veterinary use, food for babies; Dietary supplements for human beings and animals; Plasters, materials for dressings; materials for stopping teeth; dental wax; Disinfectants; Preparations for destroying vermin; Fungicides, herbicides; medicated gels; medicated creams; medicated lotions; medicated sprays; medicated adhesive plasters; medicated poultices; medicated oils; medicated liniments; medicated ointments; medicated patches; medicated pads; medicated foam; medicated tablets; gauze for dressing; bandages for dressings; adhesive plasters; transdermal anti-inflammatory analgesic pharmaceuticals; cooling sprays for medical purposes. Surgical, medical, dental and veterinary apparatus and instruments; artificial limbs, eyes and teeth; orthopaedic articles; suture materials; therapeutic and assistive devices adapted for persons with disabilities; massage apparatus; apparatus, devices and articles for nursing infants; sexual activity apparatus, devices and articles; Ice bag pillows [for medical purposes]; contraceptives, non-chemical; artificial tympanic membranes; ear plugs for sleeping; esthetic massage apparatus for industrial purposes; medical apparatus and instruments; electric massage apparatus for household purposes; gloves for medical purposes; urinals [for medical purposes]; ear picks; medical devices and instruments for transdermal drug administration consisting of micro needles and an adhesive patch; gel-type cooling pads or patches for absorbing and radiating sudden heat in human body; air activated heat pads for medical purposes; heating pads for medical purposes; ice bags for medical purposes; heating apparatus for medical purposes; body warmers for medical use; Supporters for medical purposes; apparatus for magnet therapy; moxibustion apparatus; medical pads and patches for moxibustion therapy; kinesiology tapes; drug delivery systems, namely, medical device for the transdermal delivery of drugs; sanitary masks for medical purposes; masks for use by medical personnel; medical masks; surgical masks. Advertising; Business management; Business administration; Office functions; Business management of sports people; Promotion of goods and services through sponsorship of sports events; Commercial administration of the licensing of the goods and services of others; Commercial information and advice for consumers in the choice of products and services; Media relations services; News clipping services; Import-export agency services; Distribution of samples; Retail services or wholesale services for pharmaceutical, veterinary and sanitary preparations and medical supplies; Retail and wholesale services connected with the sale of pharmaceutical preparations, gauze for dressing, bandages for dressings, adhesive plasters, adhesive tape or sheets to secure medicated plasters to the body, nutritional supplements, cosmetics, beauty masks, moist wipes for sanitary and cosmetic purposes, medicated soap, body deodorants; retail and wholesale services connected with the sale of sanitizers for household use, air activated heating pads or patches, heating patches for medical purposes, medical apparatus and instruments, cooling patches for medical purposes, cooling sprays for medical purposes, insect repellents for use on humans, supporters for medical purposes and sanitary masks.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Absorbent cotton; adhesive bandages; adhesive bandages for skin wounds; adhesive plasters; adhesive plasters for medical purposes; analgesics; anti-inflammatory preparations; bandages for dressings; breast-nursing pads; cotton sticks for medical purposes; cotton swabs for medical purposes; cotton wool for medical purposes; dental cements; dental wax; dietary supplements for general health and well-being; ear bandages; empty capsules for pharmaceuticals; eye patches for medical purposes; gauze for dressings; materials for artificial teeth; materials for dental fillings; medical plasters; menstruation bandages; menstruation tampons; sanitary napkins; sanitary panties; surgical adhesives; veneer for prosthetic dentistry
(2) Medicated transdermal patches for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal plasters for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal cataplasms for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal gels for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal creams for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal liquid for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal sprays for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; medical sprays comprised of water and alcohol in an atomized container used to produce a cooling effect;
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Absorbent cotton; adhesive bandages; adhesive bandages for skin wounds; adhesive plasters; adhesive plasters for medical purposes; analgesics; anti-inflammatory preparations; bandages for dressings; breast-nursing pads; cotton sticks for medical purposes; cotton swabs for medical purposes; cotton wool for medical purposes; dental cements; dental wax; dietary supplements for general health and well-being; ear bandages; empty capsules for pharmaceuticals; eye patches for medical purposes; gauze for dressings; materials for artificial teeth; materials for dental fillings; medical plasters; menstruation bandages; menstruation tampons; sanitary napkins; sanitary panties; surgical adhesives; veneer for prosthetic dentistry
(2) Medicated transdermal patches for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal plasters for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal cataplasms for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal gels for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal creams for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal liquid for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; Medicated transdermal sprays for relief of aches, pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; medical sprays comprised of water and alcohol in an atomized container used to produce a cooling effect;
This adhesive patch with cover material comprises an adhesive patch part which has a support body and a medicinal layer that is formed on the support body, and a cover part which has a cover layer and a cover adhesive layer that is formed on the cover layer, wherein the cover adhesive layer is joined to the support body so as to cover the adhesive patch part. The cover layer is made from a nonwoven fabric, and has a coefficient of extension of 50-300% in the flow direction and the width direction. The cover adhesive layer is formed using a rubber adhesive that has a rubber adhesive base as a main adhesive base thereof, and has a loss tangent (tan δ) of 0.7-0.95 at 30ºC and 0.1Hz.
A method for inhibiting the generation of diclofenac indolinones in an adhesive patch is provided. This adhesive patch comprises a support body layer and an adhesive layer that is layered on the support body layer. The aforementioned method includes a step for mixing a diclofenac free acid and an adhesive base to acquire an adhesive composition, and a step for shaping the adhesive composition to obtain an adhesive patch. The content of the diclofenac free acid is 0.5-8 mass% on the basis of the total mass of the adhesive layer.
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
a mass ratio between the content of the alum and the content of the sodium edetate (the content of the alum: the content of the sodium edetate) is 1:1 to 5.25:1.
Disclosed is a patch for alleviating cancerous pain. The patch is provided with a support layer and an adhesive layer laminated on the support layer. The adhesive layer contains an adhesive base and 150-225 mg of diclofenac sodium. One patch is used by being attached once per day.
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
The present invention provides a patch for relieving lumbago, the patch comprising a backing and an adhesive layer laminated on the backing, wherein the adhesive layer comprises an adhesive base and 0.70 to 1.50 mg of diclofenac sodium per cm2 of application area, and the patch is used by applying the patch once a day to the chest region, the abdominal region, the dorsal region, the brachial region, or the femoral region of a human.
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
Disclosed is a patch for relieving cancer pain, the patch comprising a support layer, and an adhesive layer laminated on the support layer, wherein the adhesive layer contains an adhesive base and diclofenac sodium. The patch is applied once a day, and is used such that the dosage of the diclofenac sodium is 150-225 mg per dose.
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceuticals, medical and veterinary preparations; sanitary preparations for medical purposes; dietetic food and substances adapted for medical or veterinary use, food for babies; dietary supplements for human beings and animals; plasters, materials for dressings; material for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicides; medicated gels; medicated creams; medicated lotions; medicated sprays; medicated adhesive plasters; medicated poultices; medicated oils; medicated liniments; medicated ointments; medicated patches; medicated pads; medicated foam; medicated tablets; gauze for dressing; bandages for dressings; adhesive plasters; transdermal anti-inflammatory analgesic pharmaceuticals; cooling sprays for medical purposes; Pharmaceutical preparations for the treatment and prevention of excessive perspiration; pharmaceutical preparations for use in treating hand perspiration; pharmaceutical preparations for use in treating foot perspiration; pharmaceutical preparations for maschalephidrosis; pharmaceutical preparations for topical hyperhidrosis; remedies for perspiration for medical purposes; remedies for hand perspiration for medical purposes; remedies for foot perspiration for medical purposes; remedies for armpit perspiration for medical purposes; remedies for topical hyperhidrosis for medical purposes; deodorants other than for personal use.
A microneedle patch according to one example comprises a support body, an adhesive layer provided on the main surface of the support body, and a microneedle array at least partially located in the adhesive layer. The adhesive layer contains a water-soluble polymer and water. The adhesive layer has, under measurement conditions including an environment temperature of 25°C and a frequency of 1 Hz, a loss tangent of 0.20-0.41.
A61K 47/58 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin
The present invention aims to provide a method for producing a microneedle device comprising a coating comprising dexmedetomidine and isoproterenol, in which the stability of isoproterenol during production and after production of the microneedle device is high. A method for producing a microneedle device according to one embodiment of the present invention comprises coating microneedles with a coating liquid to form a coating on the microneedles. The microneedle device comprises a substrate, microneedles disposed on the substrate, and a coating formed on the microneedles. The coating liquid comprises dexmedetomidine or a pharmaceutically acceptable salt thereof, isoproterenol or a pharmaceutically acceptable salt thereof, ethylenediaminetetraacetic acid or a pharmaceutically acceptable salt thereof, and a sulfated polysaccharide.
A method for improving holding power of an adhesive agent layer in a ropinirole-containing patch comprising a backing layer and the adhesive agent layer, wherein the adhesive agent layer contains at least one selected from the group consisting of ropinirole and a pharmaceutically acceptable salt thereof and an adhesive agent, the method comprising:
causing the adhesive agent layer to further contain a sodium salt of carbonic acid.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Absorbent cotton; adhesive plasters for medical purposes; bandages for dressings; breast-nursing pads; cotton sticks for medical purposes; cotton swabs for medical purposes; cotton wool for medical purposes; dental cements; dental wax; ear bandages; empty capsules for pharmaceuticals; eye patches for medical purposes; gauze for dressings; materials for artificial teeth; menstruation bandages; menstruation tampons; sanitary napkins; sanitary panties
(2) Medicated transdermal patches, plasters, cataplasms, gels, creams, liquid and sprays for the relief of aches and pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; anti-inflammatory and analgesic agents; adhesive bandages for dressing skin wounds; dietary supplements for general health and well-being for humans; medical sprays comprised of water and alcohol in an atomized container used to produce a cooling effect; adhesive plasters, namely, adhesive bandages, surgical adhesives, medical plasters; veneer for prosthetic dentistry and fillings.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceuticals, medical and veterinary preparations; sanitary preparations for medical purposes; dietetic food and substances adapted for medical or veterinary use, food for babies; dietary supplements for human beings and animals; plasters, materials for dressings; material for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicides; medicated gels; medicated creams; medicated lotions; medicated sprays; medicated adhesive plasters; medicated poultices; medicated oils; medicated liniments; medicated ointments; medicated patches; medicated pads; medicated foam; medicated tablets; gauze for dressing; bandages for dressings; adhesive plasters; transdermal anti-inflammatory analgesic pharmaceuticals; cooling sprays for medical purposes.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceuticals, medical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic food and substances adapted for medical or veterinary use, food for babies; Dietary supplements for human beings and animals; Plasters, materials for dressings; Material for stopping teeth, dental wax; Disinfectants; Preparations for destroying vermin; Fungicides, herbicides; medicated gels; medicated creams; medicated lotions; medicated aerosols; medicated sprays; medicated plasters; medicated cataplasms; medicated poultices; medicated oils; medicated liniments; medicated ointments; medicated patches; medicated pads; medicated foam; medicated tablets; gauze for dressing; bandages for dressings; adhesive plasters; transdermal anti-inflammatory analgesic pharmaceuticals; cooling sprays for medical purposes; mosquito-repellent patches; insect-repellents; insect repellent in the nature of patches, sheets, adhesive stickers, sprays, liniments; anthelmintics; biocides; preparations for destroying noxious animals; bracelets impregnated with insect repellent; insect repellent incense.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceuticals, medical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic food and substances adapted for medical or veterinary use, food for babies; Dietary supplements for human beings and animals; Plasters, materials for dressings; Material for stopping teeth, dental wax; Disinfectants; Preparations for destroying vermin; Fungicides, herbicides; medicated gels; medicated creams; medicated lotions; medicated aerosols; medicated sprays; medicated plasters; medicated cataplasms; medicated poultices; medicated oils; medicated liniments; medicated ointments; medicated patches; medicated pads; medicated foam; medicated tablets; gauze for dressing; bandages for dressings; adhesive plasters; transdermal anti-inflammatory analgesic pharmaceuticals; cooling sprays for medical purposes; mosquito-repellent patches; insect-repellents; insect repellent in the nature of patches, sheets, adhesive stickers, sprays, liniments; anthelmintics; biocides; preparations for destroying noxious animals; bracelets impregnated with insect repellent; insect repellent incense.
81.
ROPINIROLE-CONTAINING PATCH AND METHOD FOR IMPROVNG SKIN PERMEABILITY OF ROPINIROLE
A ropinirole-containing patch comprising an adhesive agent layer and a backing layer, wherein
the adhesive agent layer containing:
at least one selected from the group consisting of ropinirole and a pharmaceutically acceptable salt thereof;
a fatty acid metal salt having 7 or more carbon atoms; and
an adhesive agent.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Antistatic preparations for household purposes; de-greasing
preparations for household purposes; rust removing
preparations; stain removing benzine; fabric softeners for
laundry use; laundry bleach; adhesives for affixing false
hair; laundry starch; adhesives for affixing false
eyelashes; breath freshening preparations for personal
hygiene; deodorants for animals; paint stripping
preparations; shoe cream; shoe black [shoe polish];
polishing preparations; soaps and detergents; dentifrices;
cosmetics; perfume; incense; abrasive paper [sandpaper];
abrasive cloth; abrasive sand; artificial pumice stone;
polishing paper; false nails; false eyelashes; beauty masks. Pharmaceutical preparations; pharmaceutical preparations and
other preparations for destroying vermin, fungicides,
herbicides; insect repellents; parasiticides; anthelmintics;
reagent paper for medical purposes; adhesive tapes for
medical purposes; drug delivery agents in the form of edible
wafers for wrapping powdered pharmaceuticals; gauze for
dressings; empty capsules for pharmaceuticals; eyepatches
for medical purposes; ear bandages; menstruation bandages;
menstruation tampons; sanitary napkins; sanitary panties;
absorbent cotton; adhesive plasters; bandages for dressings;
liquid bandages; breast-nursing pads; cotton swabs for
medical use; dental materials; diapers for incontinence;
surgical implants comprised of living tissues; fly catching
paper; mothproofing paper; lacteal flour for babies; dietary
supplements for humans; dietetic beverages adapted for
medical purposes; dietetic foods adapted for medical
purposes; dietetic beverages for babies adapted for medical
purposes; food for babies; dietary supplements for animals;
semen for artificial insemination; cooling sprays for
medical purposes. Finger guards for medical purposes; sanitary masks;
pacifiers for babies; ice bag pillows for medical purposes;
support bandages; surgical catguts; feeding cups for medical
purposes; dropping pipettes for medical purposes; teats; ice
bags for medical purposes; medical ice bag holders; baby
bottles; nursing bottles; heating and cooling apparatus for
affected areas filled with chemical substances that react
when required to warm or cool the body for medical purposes;
covers for medical use to support heating and cooling
apparatus for affected areas filled with chemical substances
that react when required to warm or cool the body; heating
and cooling apparatus for affected areas administered with
chemical substances that react when required to warm or cool
the body for medical purposes; adhesive sheets for medical
purposes used to apply heating and cooling apparatus for
affected areas administered with chemical substances that
react when required to warm or cool the body; cooling
patches for medical purposes; contraceptives, non-chemical;
artificial tympanic membranes; ear plugs for sleeping; ear
plugs for soundproofing; medical apparatus and instruments;
orthopaedic articles; thermal packs for first aid purposes;
electric massage apparatus for household purposes; gloves
for medical purposes; urinals being vessels; bed pans; ear
picks; disposable steam-heated patches for therapeutic
purposes.
A method for treating hyperhidrosis is disclosed. The method comprises administering a liquid topical preparation to a patient in need thereof. The liquid topical preparation comprises water and oxybutynin or a pharmaceutically acceptable salt thereof. The oxybutynin or pharmaceutically acceptable salt thereof is present in a range of, for example, from 10 mass % to 20 mass % based on a total mass of the liquid topical preparation.
A61K 31/222 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
A61K 9/00 - Medicinal preparations characterised by special physical form
The packaging bag according to one example includes a bag body for accommodating a plurality of folded patches, an outlet formed in the bag body, and a flap label for covering the outlet so that the outlet can be opened and closed. The outlet is formed so that Lp/La is 1.5-2.5 and Lq/Lb is 1.8-2.8, where La is a first length of the outlet along a first direction, Lp is a first length of the folded patches along the first direction, Lb is a second length of the outlet along a second direction orthogonal to the first direction and shorter than the first length, and Lq is a second length of the folded patches along the second direction.
Disclosed is a transdermal patch for treating osteoarthritis. The transdermal patch comprises a support layer and an adhesive layer laminated on the support layer. The adhesive layer includes an adhesive base, diclofenac sodium, dimethyl sulfoxide, and an organic acid. The organic acid content is 6-8 mass% of the total mass of the adhesive layer. The transdermal patch is applied once daily to an affected part and the dosage of diclofenac sodium per application is 70-150 mg.
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
A61P 19/02 - Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
86.
PACKAGED PRODUCT OF DICLOFENAC-CONTAINING ADHESIVE PATCH AND METHOD FOR STABILIZING DICLOFENAC SODIUM
A packaged product of a diclofenac-containing adhesive patch, the packaged product being obtained by having a diclofenac-containing adhesive patch, which comprises a support layer and an adhesive layer that contains diclofenac sodium as a medicament, while containing dimethyl sulfoxide as a dissolving agent, sealed in a packaging bag. With respect to this packaged product of a diclofenac-containing adhesive patch, the packaging bag is formed of a multilayer body which comprises at least an innermost layer that is formed of at least one substance that is selected from the group consisting of a polyethylene terephthalate and a cycloolefin polymer, an oxygen blocking layer that is arranged on the outer side of the innermost layer, and an outer layer that is arranged on the outer side of the oxygen blocking layer.
A61J 1/00 - Containers specially adapted for medical or pharmaceutical purposes
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
Disclosed is a method for treating osteoarthritis comprising a step of administering a patch to a patient. The patch comprises a backing layer and an adhesive layer laminated on the backing layer, the adhesive layer comprises an adhesive base, diclofenac sodium, dimethyl sulfoxide, and an organic acid, and a content of the organic acid is 6 mass % to 8 mass % with respect to a total mass of the adhesive layer. The patch is applied to an affected part once a day, and a dose of diclofenac sodium per administration is 70 mg to 150 mg.
A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
The present invention provides a rotigotine-containing patch comprising:
a backing layer; and
an adhesive agent layer, wherein
the adhesive agent layer contains rotigotine and/or a pharmaceutically acceptable salt thereof, and
the adhesive agent layer further contains an alicyclic saturated hydrocarbon resin and at least one aliphatic alcohol selected from the group consisting of lauryl alcohol, octyldodecanol, oleyl alcohol, and myristyl alcohol.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Medicated transdermal patches, plasters, cataplasms, gels, liquid, creams and sprays for the relief of aches and pains of muscles and joints associated with arthritis, simple backaches, strains, bruises and sprains; topical analgesics; anti-inflammatory and analgesic agents; adhesive plasters for medical use; bandages for dressing skin wounds; dietary supplements for humans; cooling spray for medical purposes
Disclosed is a patch in which degradation of asenapine or a pharmaceutically acceptable salt thereof is inhibited. The patch comprises an adhesive layer on a base, wherein the adhesive layer contains an adhesive base, asenapine or a pharmaceutically acceptable salt thereof, and at least one basic amino acid selected from the group consisting of lysine, arginine and histidine, or a pharmaceutically acceptable salt of said basic amino acid.
A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids
A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61P 25/18 - Antipsychotics, i.e. neurolepticsDrugs for mania or schizophrenia
Disclosed is a method for inhibiting degradation of asenapine or a pharmaceutically acceptable salt thereof in a patch. The patch comprises an adhesive layer on a base, and the adhesive layer contains an adhesive base and asenapine or a pharmaceutically acceptable salt thereof. The method includes incorporating at least one amine compound selected from the group consisting of monoethanolamine, diethanolamine, diisopropanolamine, isopropanolamine, triethanolamine and meglumine in the adhesive layer.
A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61P 25/18 - Antipsychotics, i.e. neurolepticsDrugs for mania or schizophrenia
The present invention provides a transdermal patch comprising an adhesive layer on a backing, wherein the adhesive layer comprises a drug, DMSO, and an adhesive base, and the adhesive base comprises a styrene-based thermoplastic elastomer having a triblock content of 35% to 65%.
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
93.
ROPINIROLE-CONTAINING PATCH AND METHOD FOR IMPROVING SKIN PERMEABILITY OF ROPINIROLE
A ropinirole-containing patch comprising a support layer and an adhesive layer, wherein the adhesive layer contains: at least one selected from the group consisting of ropinirole and pharmaceutically acceptable salts thereof; at least one carboxylic acid sodium salt selected from the group consisting of sodium pentanoate, disodium glutarate, and sodium hexanoate; and an adhesive base agent.
A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
A61P 25/00 - Drugs for disorders of the nervous system
The present invention provides a patch comprising an adhesive layer on a backing, wherein the adhesive layer contains a adhesive base, a skin irritant drug or a pharmaceutically acceptable salt thereof, and diflucortolone valerate, and the content of the diflucortolone valerate is 0.0009 to 0.08% by mass based on the total mass of the adhesive layer.
A61K 31/27 - Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, e.g. meprobamate, carbachol, neostigmine
A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
A61K 31/403 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
A61K 31/4422 - 1,4-Dihydropyridines, e.g. nifedipine, nicardipine
A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
A cooling sheet comprising: a backing layer; an adhesive agent layer; and a liner layer for protecting the adhesive agent layer, wherein the adhesive agent layer contains
water at 65 to 85% by mass based on a total mass of the adhesive agent layer,
polyalkylene glycol monooleate at 0.12 to 0.7% by mass based on the total mass of the adhesive agent layer,
polyvinyl alcohol at 3 to 10% by mass based on the total mass of the adhesive agent layer,
polyacrylic acid at 0.5 to 5% by mass based on the total mass of the adhesive agent layer, and
a parahydroxybenzoate at 0.01 to 1% by mass based on the total mass of the adhesive agent layer, and
a mass ratio of a content of the polyvinyl alcohol to a content of the polyacrylic acid is in a range of 1.2:1 to 5:1.
The present invention provides a rotigotine stabilization method for stabilizing rotigotine and/or a pharmaceutically acceptable salt thereof in a rotigotine-containing patch comprising a backing layer and an adhesive agent layer, the adhesive agent layer containing the rotigotine and/or the pharmaceutically acceptable salt thereof and a styrene-based thermoplastic elastomer, the method comprising further incorporating cross-linked polyvinylpyrrolidone in the adhesive agent layer in a content of 3 to 25% by mass in the adhesive agent layer.
The problem addressed by the present invention is to provide a method for suppressing cold flow during packaging or application, regardless of the properties or concentration of a drug, in a patch containing a drug and an acrylic adhesive base in an adhesive layer. The present invention relates to a method for suppressing cold flow of a patch equipped with a support layer and an adhesive layer containing a drug and an acrylic adhesive base, wherein the method causes calcium silicate to be contained in the adhesive layer.
The present invention provides a gel patch having a paste layer on a support, wherein the paste layer comprising ketoprofen or a pharmaceutically acceptable salt thereof, propylene glycol, 1-menthol, and water, wherein the mass of propylene glycol in the paste layer is 3-fold the mass of ketoprofen or less, and wherein the content of 1-menthol based on a total mass of the paste layer is 0.1 to 0.5 mass %.
This coat-forming aerosol composition comprises: a stock solution containing a coat-forming agent and a solvent; and a propellant. In this coat-forming aerosol composition, an alkyl acrylate·vinyl acetate copolymer is included as the coat-forming agent, and an organic solvent having a boiling point of 30 to 100°C is included as the solvent.
A61K 8/02 - Cosmetics or similar toiletry preparations characterised by special physical form
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
The present invention provides an emulsified gel composition comprising a physiologically active substance, water, a gelling agent, an anti-peeling agent, and a surfactant having an HLB value of 18 to 20, in which the gelling agent is a nonionic water-soluble polymer, and the anti-peeling agent is one or more compounds selected from the group consisting of sucrose, sorbitol, polyethylene glycol, glycerin, a (meth)acrylic-based polymer compound, and a polyoxyethylene hydrogenated castor oil.
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
