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Found results for
 patents
1.
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Process for preparation of roflumilast
| Application Number |
14736062 |
| Grant Number |
09233925 |
| Status |
In Force |
| Filing Date |
2015-06-10 |
| First Publication Date |
2015-10-01 |
| Grant Date |
2016-01-12 |
| Owner |
SCIANDA (CHANGSHU) PHARMACEUTICALS, LTD. (China)
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| Inventor |
- Chen, Yi-Jing
- Pikul, Stanislaw
- Kuo, Shen-Chun
- Chu, Guo-Dong
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Abstract
The present invention provides novel processes for the preparation of N-substituted benzamides having the formula VIc:
In some embodiments, the invention provides a process for preparation of roflumilast and other pharmaceutically active species. Novel compounds, including intermediates for the synthesis of roflumilast, are also provided.
IPC Classes ?
- C07D 213/74 - Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- C07D 213/75 - Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
- C07C 43/315 - Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
- C07C 43/205 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
- C07C 43/307 - Compounds having groups having acetal carbon atoms bound to carbon atoms of six-membered aromatic rings
- C07D 317/22 - Radicals substituted by singly bound oxygen or sulfur atoms etherified
- C07D 319/06 - 1,3-DioxanesHydrogenated 1,3-dioxanes not condensed with other rings
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2.
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Process for preparation of roflumilast
| Application Number |
14382967 |
| Grant Number |
09085533 |
| Status |
In Force |
| Filing Date |
2013-03-07 |
| First Publication Date |
2015-01-22 |
| Grant Date |
2015-07-21 |
| Owner |
SCIANDA (CHANGSHU) PHARMACEUTICALS, LTD. (China)
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| Inventor |
- Chen, Yi-Jing
- Pikul, Stanislaw
- Kuo, Shen-Chun
- Chu, Guo-Dong
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Abstract
The present invention provides novel processes for the preparation of N-substituted benzamides having the formula (VIc). In some embodiments, the invention provides a process for preparation of roflumilast and other pharmaceutically active species. Novel compounds, including intermediates for the synthesis of roflumilast, are also provided.
IPC Classes ?
- C07D 213/74 - Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- C07D 213/75 - Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
- C07C 43/315 - Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
- C07C 43/205 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
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3.
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Process of making cladribine
| Application Number |
13429827 |
| Grant Number |
08338586 |
| Status |
In Force |
| Filing Date |
2012-03-26 |
| First Publication Date |
2012-08-02 |
| Grant Date |
2012-12-25 |
| Owner |
- SCIANDA (CHANGSHU) PHARMACEUTICALS, LTD. (China)
- SCIANDA (CHANGSHU) PHARMACEUTICALS, LTD. (China)
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| Inventor |
- Henschke, Julian Paul
- Zhang, Xiaoheng
- Guodong, Chu
- Mei, Lijun
- Chen, Yung Fa
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Abstract
c) cooling the solution of step b) so that crystals of cladribine are formed and isolated.
IPC Classes ?
- C07H 19/00 - Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radicalNucleosidesMononucleotidesAnhydro derivatives thereof
- C07H 19/22 - Pteridine radicals
- A01N 43/04 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom
- A61K 31/70 - CarbohydratesSugarsDerivatives thereof
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4.
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PROCESS FOR PREPARATION OF ROFLUMILAST
| Document Number |
02865539 |
| Status |
In Force |
| Filing Date |
2013-03-07 |
| Grant Date |
2016-08-23 |
| Owner |
SCIANDA (CHANGSHU) PHARMACEUTICALS, LTD. (China)
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| Inventor |
- Chen, Yi-Jing
- Pikul, Stanislaw
- Kuo, Shen-Chun
- Chu, Guo-Dong
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Abstract
The present invention provides novel processes for the preparation of N-substituted benzamides having the formula (VIc). In some embodiments, the invention provides a process for preparation of roflumilast and other pharmaceutically active species. Novel compounds, including intermediates for the synthesis of roflumilast, are also provided.
IPC Classes ?
- C07C 249/02 - Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
- C07D 213/75 - Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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