Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.
C09D 183/08 - Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen, and oxygen
A01N 55/00 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
B05D 1/04 - Processes for applying liquids or other fluent materials performed by spraying involving the use of an electrostatic field
B05D 7/00 - Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials
B05D 7/14 - Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials to metal, e.g. car bodies
B05D 1/02 - Processes for applying liquids or other fluent materials performed by spraying
A01N 33/08 - AminesQuaternary ammonium compounds containing oxygen or sulfur
A01N 25/02 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
C09D 5/14 - Paints containing biocides, e.g. fungicides, insecticides or pesticides
A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
C08G 77/26 - Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen, and oxygen nitrogen-containing groups
C09D 183/00 - Coating compositions based on macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon onlyCoating compositions based on derivatives of such polymers
An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R-Si(OR')3 wherein R = -(CH2)3-Y; Y = +-N(CH3)2(C18H37)X-; +-N(CH3)2(C14H29)X? +-N(C10H21)2(CH3)X?; -C1 or -NH2; X- = halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4-,or C1O4-: and R' = H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R-Si(OR')3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R-Si(OH)3.
A01N 25/02 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
A01N 33/08 - AminesQuaternary ammonium compounds containing oxygen or sulfur
C08G 77/26 - Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen, and oxygen nitrogen-containing groups
3.
BROAD SPECTRUM ANTIMICROBIAL COATINGS COMPRISING COMBINATIONS OF ORGANOSILANES
A01N 25/02 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
A01N 33/08 - AminesQuaternary ammonium compounds containing oxygen or sulfur
C08G 77/26 - Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen, and oxygen nitrogen-containing groups
C09D 183/08 - Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen, and oxygen
01 - Chemical and biological materials for industrial, scientific and agricultural use
02 - Paints, varnishes, lacquers
05 - Pharmaceutical, veterinary and sanitary products
37 - Construction and mining; installation and repair services
Goods & Services
(1) Antimicrobial coatings to prevent and inhibit the growth of mold, mildew, bacteria, viruses, and fungus on various surfaces; sanitizing preparations for commercial, industrial, and hospital use; antivirals; biocides, germicides, bactericides, and virucides; antibacterial, antiviral, and antimicrobial coatings, sprays, and preparations applied to surfaces for inhibiting the transmission infectious disease. (1) Application of coatings for others, namely, applying protective coating for the purposes of hygiene.
01 - Chemical and biological materials for industrial, scientific and agricultural use
02 - Paints, varnishes, lacquers
05 - Pharmaceutical, veterinary and sanitary products
37 - Construction and mining; installation and repair services
Goods & Services
(1) Antimicrobial coatings to prevent and inhibit the growth of mold, mildew, bacteria, viruses, and fungus on various surfaces; sanitizing preparations for commercial, industrial, and hospital use; antivirals; biocides, germicides, bactericides, and virucides; antibacterial, antiviral, and antimicrobial coatings, sprays, and preparations applied to surfaces for inhibiting the transmission infectious disease. (1) Application of coatings for others, namely, applying protective coating for the purposes of hygiene.
1422142222T1 peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
G01B 15/02 - Measuring arrangements characterised by the use of electromagnetic waves or particle radiation, e.g. by the use of microwaves, X-rays, gamma rays or electrons for measuring thickness
E. coli S. epidermidisS. epidermidis after water rinsing or after abrasion. The use of 3-chloropropyltrimethoxysilane was found to improve storage stability of the quaternary silane composition and the durability of the antimicrobial coating.
A01N 25/02 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
A01N 55/00 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
An apparatus is provided for controlling hospital acquired infections by targeting critical control points for pathogen transfer. An infection control apparatus comprises an asset tagging unit; a spraying unit; a power supply unit; optionally a DNA/RNA sequencing unit; and a computing unit comprising a non-transitory computer-readable medium encoded with program instructions for controlling the asset tagging unit and the spraying unit to perform a method of infection control in the facility. In general, the apparatus is used to identify which assets are critical control points for pathogen transfer and to treat those assets with a residual self-sanitizing coating.
A method for controlling infections in a facility such as a hospital or foodservice establishment is provided. The method comprises tagging assets, monitoring asset location and pathogen contamination for each asset over time, analyzing data sets to identify which assets are the critical control points for pathogen transfer, and coating a residual self- sanitizing coating composition on each asset identified as a critical control point. The infection control method shuts down pathogen transfer routes by mitigating or eliminating pathogen growth on the critical control points.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
H04Q 5/10 - Signalling by continuous AC using single frequencies for different subscribers
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
The disclosure provides an antimicrobial sponge comprising: a porous sponge substrate; and an antimicrobial coating composition dried therein, the composition comprising: at least one organosilane of formula (R133Si-R2-Z; and an organic amine of formula R9R10R11N, wherein each R1is independently H, alkyl, substituted alkyl, aryl, or substituted aryl, R2is a bivalent linker, and Z is a nucleophile, a leaving group or a quaternary nitrogen substituent, and wherein R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.
A01N 37/52 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing groups, e.g. carboxylic acid amidines
A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof
11.
ANTIMICROBIAL COATINGS FOR MEDICAL DRESSINGS AND DRY ANTIMICROBIAL MEDICAL DRESSINGS THEREFROM
Antimicrobial coating compositions are used to form dried residual antimicrobial coatings on medical dressings including gauze, bandages, gowns and dry wipers. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si-R2-Z, an organic amine R9R10R11N, a titanium (IV) species, a 1,2-diol, an α-hydroxy acid, a β- hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.
C08G 77/00 - Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon
C08G 77/12 - Polysiloxanes containing silicon bound to hydrogen
C08G 77/14 - Polysiloxanes containing silicon bound to oxygen-containing groups
The present disclosure provides antimicrobial coating compositions that are used to form residual antimicrobial coatings on medical implements and medical devices including the components of medical equipment such as CPAP/BiPAP machines. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si-R2-Z, an organic amine R9R10R11N, a titanium (IV) species, a 1,2-diol, an α-hydroxy acid, a β-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent, and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic. 554
C08G 77/00 - Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon
C08G 77/12 - Polysiloxanes containing silicon bound to hydrogen
C08G 77/14 - Polysiloxanes containing silicon bound to oxygen-containing groups
C09D 5/14 - Paints containing biocides, e.g. fungicides, insecticides or pesticides
A01N 29/00 - Biocides, pest repellants or attractants, or plant growth regulators containing halogenated hydrocarbons
A01N 33/04 - Nitrogen directly attached to aliphatic or cycloaliphatic carbon atoms
A01N 55/00 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
A61L 2/16 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor using chemical substances
C09D 5/14 - Paints containing biocides, e.g. fungicides, insecticides or pesticides
15.
COMPOSITION AND METHOD TO FORM A SELF DECONTAMINATING SURFACE
A polymeric material formed by reacting aminopolyol having a structure: wherein R4is selected from the group consisting of -H and -CH2-CH2-OH; and an organosilane, wherein said organosilane has a structure:: wherein R1 is selected from the group consisting of -H, -CH3 and -CH2-CH3 and R2 is selected from the group consisting of -OH, -O-CH3, 0-CH2-CH3, alkyl, alkyl with a chlorine moiety, alkyl with an amino moiety, and alkyl with a quaternary ammonium group.
C08L 83/16 - Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen, or carbon onlyCompositions of derivatives of such polymers in which all the silicon atoms are connected by linkages other than oxygen atoms
C09D 183/16 - Coating compositions based on macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon onlyCoating compositions based on derivatives of such polymers in which all the silicon atoms are connected by linkages other than oxygen atoms
16.
COMPOSITION AND METHOD TO FORM A SELF DECONTAMINATING SURFACE
A polymeric material formed by reacting aminopolyol having a structure: wherein R4 is selected from the group consisting of -H and -CH2-CH2-OH; and an organosilane, wherein said organosilane has a structure:: wherein R1 is selected from the group consisting of -H, -CH3 and -CH2-CH3 and R2 is selected from the group consisting of -OH, -O-CH3, 0-CH2-CH3, alkyl, alkyl with a chlorine moiety, alkyl with an amino moiety, and alkyl with a quaternary ammonium group.
C08G 77/00 - Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon
C08L 83/00 - Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen, or carbon onlyCompositions of derivatives of such polymers
A fluid filtration apparatus 100, which includes a plurality of optical fibers 104 each having a length, wherein one or more of the plurality of optical fibers 104 exhibits frustrated total internal reflection, thereby emitting light along the length of one or more of the optical fibers 104, in combination with a photocatalyst 109 disposed on the plurality of optical fibers 104 and a light source 114 interconnected to the plurality of optical fibers 104.
B01D 39/00 - Filtering material for liquid or gaseous fluids
B01D 35/00 - Filtering devices having features not specifically covered by groups , or for applications not specifically covered by groups Auxiliary devices for filtrationFilter housing constructions
B01D 46/00 - Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
A method to prepare a self-decontaminating surface, where that method includes disposing a first coating on a surface, where that first coating comprises an organosilane, and disposing a second coating over the first coating, where the second coating comprises TiO2.
