A robotic pipettor with pipette heads that are less than 9 mm wide, contain the mechanical components for the dispense drive and tip coupling mechanism, and are designed such that a user can replace the heads without tools.
A robotic pipettor with pipette heads that are less than 9 mm wide, contain the mechanical components for the dispense drive and tip coupling mechanism, and are designed such that a user can replace the heads without tools.
Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from, respectively, a pipette tip coupler mounted on a pipette device, are disclosed. The pipette tip couplers include an elastomeric element and an annular ring shaped raceway. When the pipette tip is mounted on the pipette tip coupler, the annular ring shaped raceway abuts a first portion of the interior surface of the circumscribing sidewall of the pipette tip, and the elastomeric element abuts a second portion of the interior surface of the circumscribing sidewall of the pipette tip.
Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from, respectively, a pipette tip coupler mounted on a pipette device, are disclosed. The pipette tip couplers include an elastomeric element and an annular ring shaped raceway. When the pipette tip is mounted on the pipette tip coupler, the annular ring shaped raceway abuts a first portion of the interior surface of the circumscribing sidewall of the pipette tip, and the elastomeric element abuts a second portion of the interior surface of the circumscribing sidewall of the pipette tip.
Pipette assembly comprising a pipette device, a pipette tip, and a leaf spring coupling device coupling the tip to the pipette device, the coupling device comprising a plurality of circumferentially disposed elements or segments in the form of flexible leaf springs with stabilizer plateaus used to retain a pipette tip to the coupler and prevent the pipette tip from rocking on the coupler and a distal elastomeric element, such as an O-ring, and the pipette tip comprising dual complemental working surfaces in the pipette tip to provide precise control of an axial coupled position defined as an axial distance from a distally facing axial stop surface of the pipette tip coupler to the end of the pipette tip that contacts liquid when the pipette tip coupler and disposable pipette tip are in a coupled configuration.
Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from, respectively, a pipette tip coupler mounted on a pipette device, are disclosed. The pipette tip couplers include an elastomeric element and an annular ring shaped raceway. When the pipette tip is mounted on the pipette tip coupler, the annular ring shaped raceway abuts a first portion of the interior surface of the circumscribing sidewall of the pipette tip, and the elastomeric element abuts a second portion of the interior surface of the circumscribing sidewall of the pipette tip.
Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.
Pipette assembly comprising a pipette device, a pipette tip, and an expanding mandrel collet coupling device coupling the tip to the pipette device, the coupling device comprising a central body, a spacer with cogs circumscribing a central body, an expanding mandrel collet circumscribing the spacer having an annular base and circumferentially spaced apart upwardly extending collet arms wherein the cogs protrude through spaces between the arms, and an elastomeric element circumscribing the central body. The collet arms are attached to the annular base and configured to expand between a first and a second greater circumference for engaging a first interior working surface of the tip in concurrence with the elastomeric element sealing against a second interior working surface below the first surface and in concurrence with an abutment between the cogs and a stepped interior shoulder of the pipette tip disposed between the first and second working surfaces.
Pipette assembly that includes a pipette device, a pipette tip, and a leaf spring coupling device coupling the tip to the pipette device, the coupling device includes a plurality of circumferentially disposed elements or segments in the form of flexible leaf springs with stabilizer plateaus used to retain a pipette tip to the coupler and prevent the pipette tip from rocking on the coupler and a distal elastomeric element, such as an O-ring, and the pipette tip includes dual complemental working surfaces in the pipette tip to provide precise control of an axial coupled position defined as an axial distance from a distally facing axial stop surface of the pipette tip coupler to the end of the pipette tip that contacts liquid when the pipette tip coupler and disposable pipette tip are in a coupled configuration.
Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.
Pipette assembly that includes a pipette device, a pipette tip, and a leaf spring coupling device coupling the tip to the pipette device, the coupling device comprising a plurality of circumferentially disposed elements or segments in the form of flexible leaf springs with stabilizer plateaus used to retain a pipette tip to the coupler and prevent the pipette tip from rocking on the coupler and a distal elastomeric element, such as an O-ring, and the pipette tip comprising dual complemental working surfaces in the pipette tip to provide precise control of an axial coupled position defined as an axial distance from a distally facing axial stop surface of the pipette tip coupler to the end of the pipette tip that contacts liquid when the pipette tip coupler and disposable pipette tip are in a coupled configuration.
Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from, respectively, a pipette tip coupler mounted on a pipette device. The pipette tip couplers include an elastomeric element, a discrete segment assembly, and a coupler stop shoulder surface. The pipette tips include a groove in a first cylindrical section, a second cylindrical section, a tip stop shoulder surface at the interface of the first and second cylindrical sections, a third cylindrical section, a sealing seat surface at the interface of the second and third cylindrical sections, and a fourth section adjacent to the third cylindrical section. When the pipette tip is mounted on the pipette tip coupler, the discrete segment assembly abuts the tip groove, the coupler stop shoulder surface abuts the tip stop shoulder surface, and the elastomeric element abuts the sealing seat surface.
Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from an expanding mandrel collet coupling device. The pipette tip couplers include a central body, a spacer with cogs circumscribing the central body, an expanding mandrel collet circumscribing the spacer having an annular base and circumferentially spaced apart upwardly extending collet arms, and an elastomeric element circumscribing the central body. The cogs protrude through spaces between the collet arms. The collet arms are attached to the annular base and configured to expand between a first and a second circumference for engaging a first interior surface of the tip, with the elastomeric element sealing against a second interior surface below the first surface, and with an abutment between the cogs and a stepped interior shoulder of the pipette tip disposed between the first and second interior surfaces.
Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from a pipette tip coupler mounted on a pipette device. The pipette tip couplers include a shank, a coupler body distal to the shank, a distal stem and distal end plate distal to the coupler body, a proximal elastomeric element disposed around the shank, a distal elastomeric element disposed around the distal stem, and a coupler stop shoulder surface between the proximal elastomeric element and distal elastomeric element. When a pipette tip is mounted on the pipette tip coupler, the proximal elastomeric element abuts the interior surface of the pipette tip for securing the pipette tip to the coupler, and the distal elastomeric element abuts the interior surface of the pipette tip to form a seal between the coupler and the pipette tip.
Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from, respectively, a pipette tip coupler mounted on a pipette device. The pipette tip couplers include an elastomeric element, an annular crown shaped raceway, and a coupler stop shoulder surface. The pipette tips include a groove in a first cylindrical section, a second cylindrical section, a tip stop shoulder surface at the interface of the first and second cylindrical sections, a third cylindrical section, a sealing seat surface at the interface of the second and third cylindrical sections, and a fourth section adjacent to the third cylindrical section. When the pipette tip is mounted on the pipette tip coupler, the annular crown shaped raceway abuts the tip groove, the coupler stop shoulder surface abuts the tip stop shoulder surface, and the elastomeric element abuts the sealing seat surface.
The invention is directed to a pipette assembly that includes a pipette device, a pipette tip, and an expanding mandrel collet coupling device coupling the tip to the pipette device, the coupling device comprising a central body, a spacer with cogs circumscribing a central body, an expanding mandrel collet circumscribing the spacer having an annular base and circumferentially spaced apart upwardly extending collet arms wherein the cogs protrude through spaces between the arms, and an elastomeric element circumscribing the central body. The collet arms are attached to the annular base and configured to expand between a first and a second greater circumference for engaging a first interior working surface of the tip in concurrence with the elastomeric element sealing against a second interior working surface below the first surface and in concurrence with an abutment between the cogs and a stepped interior shoulder of the pipette tip disposed between the first and second working surfaces.
An automated positive pressure solid phase extraction apparatus and method comprising two tiered lifts devices each individually controllable to individually vertically translate within an elevator framework between a base on which the elevator framework is mounted and a manifold plate supported by the framework in a substantially horizontal plane parallel with and vertically above the two tiered lifts devices and a rectilinearly translating shuttle assembly comprising a shuttle supporting labware for rectilinear travel into and out of the elevator framework to handoff the labware to one of the two tiered elevator lifts or both.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
B65G 47/82 - Rotary or reciprocating members for direct action on articles or materials, e.g. pushers, rakes, shovels
Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from a pipette tip coupler mounted on a pipette device. The pipette tip couplers include a proximal elastomeric element, a distal elastomeric element, and a coupler stop shoulder surface between the elastomeric elements. The pipette tips include a groove in a first cylindrical section, a second cylindrical section, a tip stop shoulder surface at the interface of the first and second cylindrical sections, a third cylindrical section distal to the second cylindrical section, and a sealing seat surface at the interface of the second and third cylindrical sections. When the pipette tip is mounted on the pipette tip coupler, the proximal elastomeric element abuts the tip groove, the coupler stop shoulder surface abuts the tip stop shoulder surface, and the distal elastomeric element abuts the sealing seat surface.
Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from an expanding mandrel pipette tip coupler mounted on a pipette device. The pipette tip couplers include circumferentially spaced apart segments for engaging an interior surface of a pipette tip, an annular base disposed below the segments, a distal elastomeric element disposed around a distal stem portion for sealing against the interior surface of the pipette tip, upwardly extending circumferentially spaced apart arms each supporting a different segment, and a stop disk for abutting a stop shoulder in a pipette tip. The pipette tips include a groove in a first cylindrical section, a second cylindrical section, a pipette tip stop shoulder surface, a third cylindrical section, and a sealing seat surface.
Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from, respectively, a pipette tip coupler mounted on a pipette device. The pipette tip couplers include an elastomeric element, a discrete segment assembly, and a coupler stop shoulder surface. The pipette tips include a groove in a first cylindrical section, a second cylindrical section, a tip stop shoulder surface at the interface of the first and second cylindrical sections, a third cylindrical section, a sealing seat surface at the interface of the second and third cylindrical sections, and a fourth section adjacent to the third cylindrical section. When the pipette tip is mounted on the pipette tip coupler, the discrete segment assembly abuts the tip groove, the coupler stop shoulder surface abuts the tip stop shoulder surface, and the elastomeric element abuts the sealing seat surface.
Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from, respectively, a pipette tip coupler mounted on a pipette device. The pipette tip couplers include an elastomeric element, a discrete segment assembly, and a coupler stop shoulder surface. The pipette tips include a groove in a first cylindrical section, a second cylindrical section, a tip stop shoulder surface at the interface of the first and second cylindrical sections, a third cylindrical section, a sealing seat surface at the interface of the second and third cylindrical sections, and a fourth section adjacent to the third cylindrical section. When the pipette tip is mounted on the pipette tip coupler, the discrete segment assembly abuts the tip groove, the coupler stop shoulder surface abuts the tip stop shoulder surface, and the elastomeric element abuts the sealing seat surface.
Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from, respectively, a pipette tip coupler mounted on a pipette device. The pipette tip couplers include an elastomeric element, a discrete segment assembly, and a coupler stop shoulder surface. The pipette tips include a groove in a first cylindrical section, a second cylindrical section, a tip stop shoulder surface at the interface of the first and second cylindrical sections, a third cylindrical section, a sealing seat surface at the interface of the second and third cylindrical sections, and a fourth section adjacent to the third cylindrical section. When the pipette tip is mounted on the pipette tip coupler, the discrete segment assembly abuts the tip groove, the coupler stop shoulder surface abuts the tip stop shoulder surface, and the elastomeric element abuts the sealing seat surface.
An automated positive pressure solid phase extraction apparatus and method comprising two tiered lifts devices each individually controllable to individually vertically translate within an elevator framework between a base on which the elevator framework is mounted and a manifold plate supported by the framework in a substantially horizontal plane parallel with and vertically above the two tiered lifts devices and a rectilinearly translating shuttle assembly comprising a shuttle supporting labware for rectilinear travel into and out of the elevator framework to handoff the labware to one of the two tiered elevator lifts or both.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
B65G 47/82 - Rotary or reciprocating members for direct action on articles or materials, e.g. pushers, rakes, shovels
An automated positive pressure solid phase extraction apparatus and method comprising two tiered lifts devices each individually controllable to individually vertically translate within an elevator framework between a base on which the elevator framework is mounted and a manifold plate supported by the framework in a substantially horizontal plane parallel with and vertically above the two tiered lifts devices; a rectilinearly translating shuttle assembly comprising a shuttle supporting labware for rectilinear travel into and out of the elevator framework to handoff the labware to one of the two tiered elevator lifts or both; and a reagent dispensing system comprising a reagent dispensing manifold for dispensing liquids into wells of each column of wells of a labware filter plate carried by the shuttle.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
B65G 47/82 - Rotary or reciprocating members for direct action on articles or materials, e.g. pushers, rakes, shovels
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
G01N 30/00 - Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
25.
Pipetting device, pipette tip coupler, and pipette tip: devices and methods
Pipette assembly comprising a pipette device, a pipette tip, and an expanding mandrel collet coupling device coupling the tip to the pipette device, the coupling device comprising: circumferentially spaced apart segments, an annular base disposed below the segments and comprising a distal portion, an elastomeric element circumscribing the distal portion, and upwardly extending circumferentially spaced apart arms attached at first ends to the annular base and having upper free ends each supporting a different one of the segments configured to expand between a first and a second greater circumference for engaging a first interior working surface of the tip in concurrence with the elastomeric element sealing against a second interior working surface below the first surface and in concurrence with an abutment between a disk exteriorly disposed about a medial portion of the arms and a stepped interior shoulder of the tip disposed between the first and second working surfaces.
Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a first elastomeric element carried by the coupler at a location superior to the coupler shoulder; and a second elastomeric element carried by the coupler at a location inferior to the coupler shoulder wherein the first elastomeric element has a compressed radially expanded state that provides a sealing abutment with a first working surface formed in the interior surface of the pipette tip while compressing the second elastomeric element into sealing abutment with a second working surface formed in the interior surface of the pipette tip and while abutting the proximally facing axial stop surface of the pipette tip with the distally facing axial stop surface of the pipette coupler to define an axial coupling position of the pipette tip on the pipette device.
Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.
Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.
Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.
Pipette assembly comprising a pipette device, a pipette tip, and an expanding mandrel collet coupling device coupling the tip to the pipette device, the coupling device comprising: circumferentially spaced apart segments, an annular base disposed below the segments and comprising a distal portion, an elastomeric element circumscribing the distal portion, and upwardly extending circumferentially spaced apart arms attached at first ends to the annular base and having upper free ends each supporting a different one of the segments configured to expand between a first and a second greater circumference for engaging a first interior working surface of the tip in concurrence with the elastomeric element sealing against a second interior working surface below the first surface and in concurrence with an abutment between a disk exteriorly disposed about a medial portion of the arms and a stepped interior shoulder of the tip disposed between the first and second working surfaces.
G01F 11/02 - Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
G01N 1/00 - SamplingPreparing specimens for investigation
G01N 1/10 - Devices for withdrawing samples in the liquid or fluent state
31.
Pipetting device, pipette tip coupler, and pipette tip: devices and methods
Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.
Pipette assembly comprising a pipette device, a pipette tip, and an expanding mandrel collet coupling device coupling the tip to the pipette device, the coupling device comprising: circumferentially spaced apart segments, an annular base disposed below the segments and comprising a distal portion, an elastomeric element circumscribing the distal portion, and upwardly extending circumferentially spaced apart arms attached at first ends to the annular base and having upper free ends each supporting a different one of the segments configured to expand between a first and a second greater circumference for engaging a first interior working surface of the tip in concurrence with the elastomeric element sealing against a second interior working surface below the first surface and in concurrence with an abutment between a disk exteriorly disposed about a medial portion of the arms and a stepped interior shoulder of the tip disposed between the first and second working surfaces.
Pipette tip couplers, pipette tips, coupler and tip combinations, and methods for coupling and decoupling a pipette tip to or from a pipette tip coupler mounted on a pipette device. The pipette tip couplers include a proximal elastomeric element, a distal elastomeric element, and a coupler stop shoulder surface between the elastomeric elements. The pipette tips include a groove in a first cylindrical section, a second cylindrical section, a tip stop shoulder surface at the interface of the first and second cylindrical sections, a third cylindrical section distal to the second cylindrical section, and a sealing seat surface at the interface of the second and third cylindrical sections. When the pipette tip is mounted on the pipette tip coupler, the proximal elastomeric element abuts the tip groove, the coupler stop shoulder surface abuts the tip stop shoulder surface, and the distal elastomeric element abuts the sealing seat surface.
Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axiaily stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.
F16L 37/08 - Couplings of the quick-acting type in which the connection between abutting or axially-overlapping ends is maintained by locking members
F16L 37/091 - Couplings of the quick-acting type in which the connection between abutting or axially-overlapping ends is maintained by locking members combined with automatic locking by means of a ring provided with teeth or fingers
F16L 37/092 - Couplings of the quick-acting type in which the connection between abutting or axially-overlapping ends is maintained by locking members combined with automatic locking by means of elements wedged between the pipe and the frusto-conical surface of the body of the connector
G01N 1/14 - Suction devices, e.g. pumpsEjector devices
G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
35.
PIPETTING DEVICE, PIPETTE TIP COUPLER, AND PIPETTE TIP: DEVICES AND METHODS
Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a first elastomeric element carried by the coupler at a location superior to the coupler shoulder; and a second elastomeric element carried by the coupler at a location inferior to the coupler shoulder wherein the first elastomeric element has a compressed radially expanded state that provides a sealing abutment with a first working surface formed in the interior surface of the pipette tip while compressing the second elastomeric element into sealing abutment with a second working surface formed in the interior surface of the pipette tip and while abutting the proximally facing axial stop surface of the pipette tip with the distally facing axial stop surface of the pipette coupler to define an axial coupling position of the pipette tip on the pipette device.
F16L 21/02 - Joints with sleeve or socket with elastic sealing rings between pipe and sleeve or between pipe and socket, e.g. with rolling or other prefabricated profiled rings
An automated positive pressure solid phase extraction apparatus and method comprising two tiered lifts devices each individually controllable to individually vertically translate within an elevator framework between a base on which the elevator framework is mounted and a manifold plate supported by the framework in a substantially horizontal plane parallel with and vertically above the two tiered lifts devices and a rectilinearly translating shuttle assembly comprising a shuttle supporting labware for rectilinear travel into and out of the elevator framework to handoff the labware to one of the two tiered elevator lifts or both.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
B65G 47/82 - Rotary or reciprocating members for direct action on articles or materials, e.g. pushers, rakes, shovels
An automated positive pressure solid phase extraction apparatus and method comprising two tiered lifts devices each individually controllable to individually vertically translate within an elevator framework between a base on which the elevator framework is mounted and a manifold plate supported by the framework in a substantially horizontal plane parallel with and vertically above the two tiered lifts devices and a rectilinearly translating shuttle assembly comprising a shuttle supporting labware for rectilinear travel into and out of the elevator framework to handoff the labware to one of the two tiered elevator lifts or both.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
B65G 47/82 - Rotary or reciprocating members for direct action on articles or materials, e.g. pushers, rakes, shovels
An automated positive pressure solid phase extraction apparatus and method comprising two tiered lifts devices each individually controllable to individually vertically translate within an elevator framework between a base on which the elevator framework is mounted and a manifold plate supported by the framework in a substantially horizontal plane parallel with and vertically above the two tiered lifts devices and a rectilinearly translating shuttle assembly comprising a shuttle supporting labware for rectilinear travel into and out of the elevator framework to handoff the labware to one of the two tiered elevator lifts or both.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
B65G 47/82 - Rotary or reciprocating members for direct action on articles or materials, e.g. pushers, rakes, shovels
An automated positive pressure solid phase extraction apparatus and method comprising two tiered lifts devices each individually controllable to individually vertically translate within an elevator framework between a base on which the elevator framework is mounted and a manifold plate supported by the framework in a substantially horizontal plane parallel with and vertically above the two tiered lifts devices and a rectilinearly translating shuttle assembly comprising a shuttle supporting labware for rectilinear travel into and out of the elevator framework to handoff the labware to one of the two tiered elevator lifts or both.
The invention relates to a method for automatically producing active ingredient beads (10; 12) with a gel-like carrier material, preferably a bio-polymer such as agarose, and with a biologically active material embedded in the carrier material, such as an active ingredient and/or a material producing an active ingredient, comprising the following steps: a) providing a free-flowing, solidifiable mixture (18), comprising the carrier material and the biologically active material, b) solidifying a core bead (10) by introducing a predetermined amount (22) of the free-flowing mixture (18) into a fluid bath (24), preferably a liquid bath, particularly preferably an oil bath, and c) removing the core bead (10) from the fluid bath (24), wherein a bead contact surface area (36; 42) of a bead receiving tool (34; 38) is used for carrying out step c), and step c) comprises to this end either the following substep ca1) or the following substep cb1): ca1) producing a contact engagement between the core bead (10) and a preferably concave bead vacuum contact surface (42) of a bead vacuum receiving tool (38) by means of vacuum, or cb1) producing a contact engagement between the core bead (10) and a preferably concave bead gravity contact surface (36) of a bead gravity receiving tool (34) in the fluid bath by means of gravity.
A shift and scan test tube rack apparatus and method comprised of an array of initially aligned racks each comprised of a row of spaced apart receptacles each having a receptacle window through which a barcode on a received barcode labeled test tube is viewable and each rack further comprised of a plurality of line of sight windows each interposed between two adjacent spaced apart receptacles, and a shifting device for individually shifting any one of the racks in the array of initially aligned racks to a shifted position that allows a plurality of the receptacle windows in the shifted rack to be viewed through the plurality of line of sight windows in the remaining aligned racks for reading barcodes on barcode labeled test tubes received in the shifted rack.
A shift and scan test tube rack apparatus and method comprised of an array of initially aligned racks each comprised of a row of spaced apart receptacles each having a receptacle window through which a barcode on a received barcode labeled test tube is viewable and each rack further comprised of a plurality of line of sight windows each interposed between two adjacent spaced apart receptacles, and a shifting device for individually shifting any one of the racks in the array of initially aligned racks to a shifted position that allows a plurality of the receptacle windows in the shifted rack to be viewed through the plurality of line of sight windows in the remaining aligned racks for reading barcodes on barcode labeled test tubes received in the shifted rack.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
A negative dead volume syringe comprising a body defining a chamber, a syringe tip disposed at a distal end of the chamber and having a tip passageway therethrough in open communication with the chamber, a rod extending from a first end within the chamber to a second end coupleable to a motor to produce bidirectional motion of the rod, and a plunger tip having a proximal portion coupled to the first end of the rod, a medial portion distally extending from said proximal portion and shaped to complement the tip passageway, and a tip extension distally extending from said medial portion and shaped to be received within a dead volume defined by a passageway of a valve coupleable to the syringe tip wherein the plunger tip ensures evacuation of fluid and air from the chamber, syringe tip, and dead volume of the valve upon distal displacement of the rod.
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
F04B 49/16 - Control of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for in, or of interest apart from, groups by adjusting the capacity of dead spaces of working chambers
A61M 5/36 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests with means for eliminating or preventing injection or infusion of air into body
F04B 53/14 - Pistons, piston-rods or piston-rod connections
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
A61M 5/315 - PistonsPiston-rodsGuiding, blocking or restricting the movement of the rodAppliances on the rod for facilitating dosing
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