Abstract

The invention relates to particles (15) comprising an agglomeration of mutually cohesive grains having a substantially spherical shape, wherein each grain consists of a mixture comprising an active agent and a cohesion agent to bind the grains together. The process for producing these particles uses spray granulation.

IPC Classes  ?

• A23L 27/00 - SpicesFlavouring agents or condimentsArtificial sweetening agentsTable saltsDietetic salt substitutesPreparation or treatment thereof
• A23L 29/212 - StarchModified starchStarch derivatives, e.g. esters or ethers
• A23P 10/20 - AgglomeratingGranulatingTabletting
• A23K 20/189 - Enzymes
• A23K 40/10 - Shaping or working-up of animal feeding-stuffs by agglomerationShaping or working-up of animal feeding-stuffs by granulation, e.g. making powders
• A23K 40/30 - Shaping or working-up of animal feeding-stuffs by encapsulatingShaping or working-up of animal feeding-stuffs by coating

Abstract

A method for the manufacture of core-membrane capsules, which manufacturing method includes: (i) a step of providing two immiscible solutions, namely: a first solution containing at least one first reactive molecule including at least two azlactone groups, and a second solution containing at least one second reactive molecule including at least two amine groups, and (ii) an interfacial polymerization step during which the immiscible solutions are mixed so that the reactive molecules react together by an interfacial polymerization reaction, on the surface of the droplets, to form the membrane including a polyamide polymer.

IPC Classes  ?

• B01J 13/16 - Interfacial polymerisation
• C08G 69/28 - Preparatory processes
• C08G 69/42 - Polyamides containing atoms other than carbon, hydrogen, oxygen, and nitrogen

Abstract

A granule comprising: sodium butyrate particles, a fatty material matrix comprising fatty acids encapsulating the sodium butyrate particles, the granule preserving its morphology following gastric and enteric digestion simulation in vitro tests, the granule featuring a gastric resistance conferring protection on the sodium butyrate particles in the stomach, and featuring a sustained release of the sodium butyrate particles in the intestinal tract.

IPC Classes  ?

• A61K 31/19 - Carboxylic acids, e.g. valproic acid
• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets

Abstract

The present invention relates to a method for manufacturing core-shell capsules, said manufacturing method comprising: (i) a step of providing two immiscible solutions, namely: - a first solution containing at least a first reactive molecule having at least two azlactone groups, and - a second solution containing at least a second reactive molecule having at least two amine groups; and (ii) an interfacial polymerisation step during which the immiscible solutions are mixed so that the reactive molecules react together by an interfacial polymerisation reaction, at the surface of said droplets, so as to form said shell comprising a polyamide polymer.

IPC Classes  ?

• B01J 13/16 - Interfacial polymerisation
• A61K 9/50 - Microcapsules
• C09B 67/02 - Dyestuff preparations characterised by special physical forms, e.g. tablets, films
• C11D 3/50 - Perfumes
• F28D 20/02 - Heat storage plants or apparatus in generalRegenerative heat-exchange apparatus not covered by groups or using latent heat

Abstract

The present invention relates to a granule comprising: - sodium butyrate particles, - a matrix of fatty material comprising fatty acids encapsulating said sodium butyrate particles, the morphology of said granule being maintained following in vitro gastric and enteric digestion simulation tests, said granule exhibiting a gastric resistance which confers protection of the sodium butyrate particles in the stomach, and exhibiting sustained release of the sodium butyrate particles in the intestinal tract.

IPC Classes  ?

• A23K 20/158 - Fatty acidsFatsProducts containing oils or fats
• A23L 33/12 - Fatty acids or derivatives thereof
• A23P 10/35 - Encapsulation of particles, e.g. foodstuff additives with oils, lipids, monoglycerides or diglycerides
• A61K 31/19 - Carboxylic acids, e.g. valproic acid

Goods & Services

Chemical products for use in industry, science and agriculture; auxiliary materials for preparations, namely coating and encapsulating agents for tablets (chemical products), none of the aforesaid goods in connection with the pharmaceutical sector. Cleaning, polishing, degreasing and abrasive preparations, soaps, perfumery, essential oils, cosmetics, cosmetic products for skin care, detergents. Deodorants (deodorizing products). Scientific and industrial research with respect to coating and/or encapsulating, research and development of new products, none of the aforesaid services in connection with the pharmaceutical sector.

Abstract

The invention relates to a microcapsule comprising a hydrophobic content surrounded by a shell system that includes a membrane comprising a combination of at least two complementary water-soluble polyelectrolytes selected from among the water-soluble polyelectrolytes that are able to create microencapsulation by complex coacervation. According to the invention, the shell system also includes solid particles selected from among the solid particles that are able to stabilize a Pickering emulsion.

IPC Classes  ?

• B01J 13/10 - Complex coacervation, i.e. interaction of oppositely charged particles
• A01N 25/28 - Microcapsules
• A61K 8/11 - Encapsulated compositions
• A61K 9/50 - Microcapsules
• C11D 3/50 - Perfumes

Abstract

Disclosed is a microcapsule including a core having an oxidizable active (OA), the outer part of said core being in a solid form, and a water insoluble coating obtained from an encapsulating agent (EA), with the coating surrounding said core. In particular, the EA can be water soluble or organic solvent soluble, in particular in ethanol. The microcapsule can also include an EA in which the water solubility is pH-dependent. Also, the core does not contain a metal oxide, and the coating does not include a disintegrant, such as sodium starch glycolate. Also disclosed is a process for preparing the microcapsules.

IPC Classes  ?

• A61K 9/50 - Microcapsules
• A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61K 8/67 - Vitamins
• A61K 31/375 - Ascorbic acid, i.e. vitamin CSalts thereof
• A23D 9/00 - Other edible oils or fats, e.g. shortenings or cooking oils
• A23L 2/52 - Adding ingredients
• A61K 38/44 - Oxidoreductases (1)
• B05D 1/22 - Processes for applying liquids or other fluent materials performed by dipping using fluidised-bed technique
• A23P 10/30 - Encapsulation of particles, e.g. foodstuff additives
• A23P 20/18 - Apparatus or processes for coating with liquid or semi-liquid products by spray-coating, fluidised-bed coating or coating by casting
• A23L 29/262 - CelluloseDerivatives thereof, e.g. ethers
• A23L 29/275 - Foods or foodstuffs containing additivesPreparation or treatment thereof containing gelling or thickening agents of animal origin, e.g. chitin
• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A23L 33/115 - Fatty acids or derivatives thereofFats or oils
• A23L 33/15 - Vitamins
• A23L 33/16 - Inorganic salts, minerals or trace elements

Abstract

Disclosed is a microcapsule including a core having an oxidizable active (OA), the outer part of said core being in a solid form, and a water insoluble coating obtained from an encapsulating agent (EA), with the coating surrounding said core. In particular, there is disclosed a microcapsule wherein the EA is water soluble or organic solvent, in particular ethanol, soluble, or a microcapsule wherein said EA is an agent, the water solubility of which is pH-dependent. In particular, the core does not consist in or comprise a metal oxide, and the coating does not comprise a disintegrant, in particular sodium starch glycolate. Also disclosed is a process for preparing the microcapsules.

IPC Classes  ?

• A61K 38/44 - Oxidoreductases (1)
• A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61K 8/11 - Encapsulated compositions
• A61K 9/50 - Microcapsules
• A23D 9/00 - Other edible oils or fats, e.g. shortenings or cooking oils
• A23L 1/30 - containing additives (A23L 1/308 takes precedence);;
• A23L 1/302 - Vitamins
• A23L 1/304 - Inorganic salts, minerals, trace elements
• A23L 1/00 - Foods or foodstuffs; Their preparation or treatment (preservation thereof in general A23L 3/00)
• A23L 2/52 - Adding ingredients
• A61K 31/375 - Ascorbic acid, i.e. vitamin CSalts thereof
• A23L 1/0534 - Cellulose; Derivatives thereof, e.g. ethers
• A23L 1/056 - of animal origin, e.g. chitin

Abstract

The present invention relates to microcapsules containing an oxidizable active, and a process for preparing the same.

IPC Classes  ?

• A23D 9/00 - Other edible oils or fats, e.g. shortenings or cooking oils
• A23L 5/00 - Preparation or treatment of foods or foodstuffs, in generalFood or foodstuffs obtained therebyMaterials therefor
• A23L 29/00 - Foods or foodstuffs containing additivesPreparation or treatment thereof
• A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives
• A23L 33/15 - Vitamins
• A23P 10/30 - Encapsulation of particles, e.g. foodstuff additives
• A61K 8/11 - Encapsulated compositions
• A61K 9/50 - Microcapsules
• B01J 13/04 - Making microcapsules or microballoons by physical processes, e.g. drying, spraying
• C12N 9/00 - Enzymes, e.g. ligases (6.)ProenzymesCompositions thereofProcesses for preparing, activating, inhibiting, separating, or purifying enzymes