GenMont Biotech Incorporation (Taiwan, Province of China)
Inventor
Tsai, Wan-Hua
Fang, Yi-Ting
Chang, Chia-Yu
Lee, Hsueh-Te
Abstract
An application based on nucleotide fragments of Lactobacillus rhamnosus GM-020, to prepare a composition for anti-lipogenesis. The Lactobacillus rhamnosus GM-020 was deposited on Dec. 18, 2003 and has the CCTCC designation number CCTCC M203098. Also provided is a composition containing Lactobacillus rhamnosus GM-020 or nucleotide fragments thereof as effective ingredients for anti-lipogenesis.
GenMont Biotech Incorporation (Taiwan, Province of China)
Inventor
Tsai, Wan-Hua
Fang, Yi-Ting
Chou, Chia-Hsuan
Kuo, Chih-Feng
Tsao, Ni-Na
Jhong, Jhih-Hua
Lee, Tzong-Yi
Abstract
A use of Lactobacillus paracasei GM-080 and peptides thereof for preparing an antimicrobial composition. The composition is a pharmaceutical composition, a nutritional supplement, or a health care food, wherein the deposit number of Lactobacillus paracasei GM-080 is BCRC 910220 or CCTCC M 204012. In addition, a peptide of Lactobacillus paracasei GM-080 and compositions thereof are provided.
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Lactic acid; Probiotic bacteria for use in the manufacture of food supplements, food, cosmetics, beverages, animal feed and pet food; Bacterial preparations, other than for medical and veterinary use; Preparations of microorganisms, other than for medical and veterinary use; Bacterial preparations for the food industry; Bacterial cultures for addition to food products Bacterial and bacteriological preparations for medical or veterinary purposes; Bacteriological cultures for medical and veterinary purposes; Diagnostic media for bacteriological cultures for medical purposes or veterinary purposes; Cultures of microorganisms for medical or veterinary use; Pharmaceutical preparations for treating allergies; Pharmaceutical anti-allergic preparations and substances; Dietetic foods adapted for medical use; Probiotic supplements; Probiotic preparations for medical use; Beverages containing probiotics or prebiotics for use as a nutritional supplement; Enzyme preparations for medical purposes; Nutritional supplements in the form of powder; Powdered nutritional supplement drink mix and concentrate; Powdered nutritional supplement drink mix containing probiotic
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Lactic acid; Bacterial preparations, other than for medical and veterinary use; Preparations of microorganisms, other than for medical and veterinary use; Bacterial preparations for the food industry; Bacterial cultures for addition to food products; Probiotic bacteria for use in the manufacture of food supplements,
food, cosmetics, beverages, animal feed and pet food Bacterial and bacteriological preparations for medical or veterinary purposes; Bacteriological cultures for medical and veterinary purposes; Diagnostic media for bacteriological cultures for medical purposes or veterinary purposes; Cultures of microorganisms for medical or veterinary use; Pharmaceutical preparations for treating allergies; Pharmaceutical anti-allergic preparations and substances; Dietetic foods adapted for medical use; Probiotic supplements; Probiotic preparations for medical use; Enzyme preparations for medical purposes; Powdered nutritional supplement drink mix and concentrate; Powdered nutritional supplement drink mix containing probiotic; Beverages containing probiotics or prebiotics for use as a nutritional supplement; Nutritional supplements in the form of powder
A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
7.
COMPOSITION WITH LACTOBACILLUS PARACASEI AND A METHOD TO TREAT NASOPHARYNGEAL CARCINOMA THROUGH PYROPTOSIS OR CELL CYCLE ARREST
GenMont Biotech Incorporation (Taiwan, Province of China)
Inventor
Tsai, Wan-Hua
Hsu, I-Ling
Chang, Wen-Wei
Lin, Chin-Chun
Abstract
A composition with Lactobacillus paracasei and a method to treat nasopharyngeal carcinoma through induction of pyroptosis or cell cycle arrest; Lactobacillus paracasei GMNL-653 or heat-killed whole-bacterial liquids thereof are taken as effective ingredients for inhibiting proliferations of nasopharyngeal carcinoma cells or reducing a probability of nasopharyngeal carcinoma development through pyroptosis or cell cycle arrest instead of the mechanism of apoptosis.
GenMont Biotech Incorporation (Taiwan, Province of China)
Inventor
Tsai, Wan-Hua
Hsu, I-Ling
Chang, Wen-Wei
Chien, Peng-Ju
Hung, Yu-Chieh
Abstract
A method for preventing or treating oral cancer includes administering a composition comprising Lactobacillus paracasei or a supernatant of the heat-killed Lactobacillus paracasei. A composition that contains an active ingredient with anti-oral cancer effect. The active ingredient is Lactobacillus paracasei GMNL-346 or the supernatant of the heat-killed GMNL-346. The deposition number of the Lactobacillus paracasei GMNL-346 is BCRC 910953 or CCTCC M 2019983.
GenMont Biotech Incorporation (Taiwan, Province of China)
Inventor
Tsai, Wan-Hua
Chang, Wen-Wei
Chou, Chia-Hsuan
Wang, I-Jen
Yeh, Wen-Ling
Jhong, Jhih-Hua
Lee, Tzong-Yi
Abstract
The invention provides an extracellular vesicle and a nucleotide fragment isolated from Lactobacillus paracasei GM-080 with the deposition number BCRC 910220 and CCTCC M 204012 and use thereof. The invention also relates to a method for modulating immune function comprising administering a composition including the extracellular vesicle and the nucleotide fragment.
Lactobacillus paracasei GMNL-653 was deposited at the China Center for Type Culture Collection located at Wuhan University, Wuhan 430072 P.R. China on Apr. 25, 2016 under an accession number CCTCC NO. M 2016226.
GENMONT BIOTECH INCORPORATION (Taiwan, Province of China)
Inventor
Tsai, Wan-Hua
Yeh, Wen-Ling
Wu, Chia-Lin
Lai, Chih-Ho
Yeh, Yao-Tsung
Huang, Cheng-Hsieh
Abstract
Lactobacillus composition can effectively improve imbalance of an individual's intestinal flora caused by antibiotics to help stabilize and increase species richness and increase the synthesis of mood-stabilizing compounds, including flavonoids, flavonols, isoquinoline alkaloids, niacinamide, nicotinamide, and short-chain fatty acids in intestine, and thus effectively improve antibiotic-induced with anxiety disorders.
Method for improving an effect of chemotherapeutic drug of gemcitabine on inhibiting pancreatic cancer and improving side effect of chemotherapeutic drug of Gemcitabine
Lactobacillus reuteri GMNL-89 was deposited in the China Center for Type Culture Collection on Nov. 19, 2007 under an accession number CCTCC NO. M 207154. A method for improving the effect of the chemotherapeutic drug of Gemcitabine on inhibiting pancreatic cancer is further disclosed in the present disclosure.
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Lactic acid; lactic acid bacteria for use in food production. Medicines for human purposes; dietary supplements for humans; neutraceutical preparations for humans; pharmaceutical preparations for human use; lactic acid bacteria supplements for humans; lactic acid bacteria supplements for animals; medicated supplements for foodstuffs for animals; dietary supplements for animals.
01 - Chemical and biological materials for industrial, scientific and agricultural use
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
Lactic acid; lactic acid bacteria for use in food production. Toothpaste; oral hygiene preparations; tooth cleaning preparations. Acid drops [confectionery]; yeast and leavening agents; lozenges [confectionery]; oatmeal; snack food products made from cereal flour; bread; biscuits; cakes; coffee-based beverages; beverages made of tea; chewing gum, not for medical purposes.
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Lactic acid; lactic acid bacteria for use in food production. Medicines for human purposes; dietary supplements for humans; neutraceutical preparations for humans; pharmaceutical preparations for human use; lactic acid bacteria supplements for humans; lactic acid bacteria supplements for animals; medicated supplements for foodstuffs for animals; dietary supplements for animals.
Lactobacillus Plantarum strain GMNL-662 has an ability to promote the expression of osteogenic genes, inhibit the expression of osteoclast related genes, and promote the expression of osteogenesis-related cytokine TGF-β, so that the bone loss is improved.
GENMONT BIOTECH INCORPORATION (Taiwan, Province of China)
Inventor
Chen, Yi-Hsing
Tsai, Wan-Hua
Huang, Shiang-Suo
Wang, Yi-Hsin
Abstract
Lactobacillus paracasei GMNL-133 is CCTCC M2011331. The composition can be taken as a dietary supplement and be given continuously after a stroke, and said composition has the effects of ameliorating cerebral infarction, motor function, and intestinal microbiota after a stroke.
A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
21.
Topical composition, pharmaceutical composition containing inactivated culture and method of facilitating wound healing and scar reduction using the same
GenMont Biotech Incorporation (Taiwan, Province of China)
Inventor
Chen, Yi-Hsing
Tsai, Wan-Hua
Chang, Wen-Wei
Chou, Chia-Hsuan
Abstract
Lactobacillus species as an effective ingredient and can significantly facilitate wound healing as well as reducing scars, thereby can be applied to a method of facilitating wound healing and reducing scars.
A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
A61K 9/00 - Medicinal preparations characterised by special physical form
A61L 15/36 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing microorganisms
22.
Lactobacillus paracasei GMNL-653 for preparing for a composition for alleviating axillary osmidrosis
GENMONT BIOTECH INCORPORATION (Taiwan, Province of China)
Inventor
Chen, Yi-Hsing
Tsai, Wan-Hua
Chou, Chia-Hsuan
Huang, Tsuei-Yin
Abstract
Lactobacillus paracasei GMNL-653, featuring abilities of aggregating and inhibiting pathogens of axillary osmidrosis for alleviation of armpit odors and presented as a topical medication or a combination of cosmetics in which fragrance is added.
Genmont Biotech Incorporation (Taiwan, Province of China)
Inventor
Chen, Yi-Hsing
Tsai, Wan-Hua
Yeh, Wen-Ling
Abstract
Lactobacillus plantarum GMNL-682; the composition of the present invention is used to prevent and treat bacterial vaginosis by inhibition of the growth of pathogens and regulation of the expression of immunoregulators and is prepared in the forms of pharmaceutical compositions, food or other combinations thereof.
GENMONT BIOTECH INCORPORATION (Taiwan, Province of China)
Inventor
Chen, Yi-Hsing
Tsai, Wan-Hua
Huang, Tsuei-Yin
Huang, Hsiang-En
Hsu, Yu-Jen
Abstract
Lactobacillus fermenting culture solution can be applied as the plant growth regulator or a use in preparation of a composition for elevating anti-stress ability of a plant.
GENMONT BIOTECH INCORPORATION (Taiwan, Province of China)
Inventor
Chen, Yi-Hsing
Tsai, Wan-Hua
Chou, Chia-Hsuan
Chiang, Ying-Ju
Abstract
Lactobacillus plantarum (GMNL-6) with preservation number of BCRC 910777 or CCTCC M 2017765. The composition may be externally-coating drug, pharmaceuticals for external use, care products for external use or cosmetics, and may achieve the effects of improving the skin conditions or aesthetic appearance by promoting secretion of collagen or expression of ceramide synthase.
A61K 8/99 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
Lactobacillus paracasei strain GMNL-653 is capable of promoting the expression of TGF-β and IL-10, while inhibiting the expression of osteoclast related genes and reducing the content of IL-17A in serum, so that the bone loss is slowed down.
Lactobacillus paracasei strain GMNL-653 has anti-inflammation properties, and inhibits the secretion of cytokine IL-6 and IL-17, so that the psoriasis symptoms caused by over-inflammation are improved/relieved.
Lactobacillus fermentum GMNL-296 is to promote the expression of anti-inflammatory cytokine IL-10 and Treg cell related transcription factors, so that the infection symptoms of weight loss and intestinal abnormalities are improved.
A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
A61K 9/00 - Medicinal preparations characterised by special physical form
A61Q 11/00 - Preparations for care of the teeth, of the oral cavity or of dentures, e.g. dentifrices or toothpastesMouth rinses
A61K 8/99 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Lactose to be used in the manufacture of foodstuffs, bacteria for use in food manufacture, fermentation extract; cultures of microorganisms for use in dietary supplements, food supplements, vitamin and mineral preparations, all for the promotion of immune health and for the reduction of the symptoms of allergies through airborne allergens including pollen and dust; pharmaceutical preparations for the promotion of immune health and for the reduction of the symptoms of allergies through airborne allergens including pollen and dust; cultures of microorganisms for use as a dietary supplement for the promotion of immune health and for the reduction of the symptoms of allergies through airborne allergens including pollen and dust; food supplements for the promotion of immune health and for the reduction of the symptoms of allergies through airborne allergens including pollen and dust
34.
Lactobacillus reuteri GMNL-263 in decreasing blood lipid levels
Lactobacillus reuteri GMNL-263 is utilized to produce a composition for decreasing blood lipid levels, thereby achieving the aim of hyperlipidemia treatment.
Lactobacillus strain including anti-oxidative enzyme activity, anti-inflammation, reduction of blood glucose level, reduction of triglycerides, reduction of total cholesterol, reduction of LDL, increase of HDL and improve insulin utilization.
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
Lactobacillus strain for controlling body weight, whose mechanism is inhibiting biosynthesis of lipids and reducing formation of lipid droplets so as to control body weight.
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A23L 1/29 - Modifying nutritive qualities of foods; Dietetic products ( A23L 1/09 takes precedence;dietetic salt substitutes A23L 1/22)
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Medicine for bacteriological cultures, namely, for treatment or improvement of allergy and for treatment of heart disease; lactobacillus for use in medication, namely, for treatment or improvement of allergy and for treatment of heart disease; lactobacillus for use in auxiliary therapy and nutritional supplements, namely, for treatment or improvement of allergy and for treatment of heart disease; allergy capsules; allergy relief medication; nutritional supplements; [ herbal supplements; food supplements, namely, anti-oxidants; ] animal feed additive for use as a nutritional supplement
40.
Lactobacillus strain, composition and use thereof for improving the syndrome of diabetes and complication thereof
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
A01N 65/00 - Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Medicine for bacteriological cultures, namely, for treatment or improvement of allergy and for treatment of heart disease; lactobacillus for use in medication, namely, for treatment or improvement of allergy and for treatment of heart disease; lactobacillus for use in auxiliary therapy and nutritional supplements, namely, for treatment or improvement of allergy and for treatment of heart disease; allergy capsules; allergy relief medication; nutritional supplements; herbal supplements; food supplements, namely, anti-oxidants; animal feed additive for use as a nutritional supplement
01 - Chemical and biological materials for industrial, scientific and agricultural use
29 - Meat, dairy products, prepared or preserved foods
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
Lactose to be used in the manufacture of foodstuffs, bacteria for use in food manufacture, fermentation extract. Milk, acidophilus milk, milk powder, dairy-based beverages, yogurt, yogurt-based beverages, cheese. Coffee, tea, chocolate powder, candy, vinegar.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Medicine for bacteriological cultures, namely, probiotics in capsules, tablets, powders or solutions for the treatment of allergies, for use to relieve allergy symptoms, alleviate inflammatory reactions in the intestines, maintain the balance of intestinal microflora, allergy medications; Lactobacillus capsules; allergy relief supplements; nutritional supplements, namely, probiotics in capsules, tablets, powders or solutions for the treatment of allergies, for use to relieve allergy symptoms, alleviate inflammatory reactions in the intestines, maintain the balance of intestinal microflora; herbal supplements for the treatment of allergies; food supplements, namely, anti-oxidants, for the treatment of allergies; Lactobacillus for use in auxiliary therapy and nutritional supplements; animal feed additive for use as a nutritional supplement.
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
29 - Meat, dairy products, prepared or preserved foods
30 - Basic staples, tea, coffee, baked goods and confectionery
31 - Agricultural products; live animals
Goods & Services
Lactose to be used in the manufacture of foodstuffs, bacteria for use in food manufacture, fermentation extract. Medicine for bacteriological cultures; allergy capsules; allergy relief medication; nutritional supplements; herbal supplements; food supplements, namely anti-oxidants; lactobacillus for use in medication; lactobacillus for use in auxiliary therapy and nutritional supplements. Milk, acidophilus milk, milk powder, dairy-based beverages, yogurt, yogurt-based beverages, cheese. Coffee, tea, chocolate powder, candy, vinegar. Animal feed additive for use as a nutritional supplement.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Cultures of microorganisms for medical and veterinary use; bacteriological preparations for medical and veterinary use; cultures of microorganisms for use in dietary supplements, food supplements, vitamin and mineral preparations; pharmaceutical and veterinary preparations, dietetic substances adapted for medical use, food for babies; cultures of microorganisms for us as a dietary supplement; food supplements; vitamin and mineral preparations.
57.
Lactobacillus isolates having anti-inflammatory activities and uses of the same
GenMont Biotech Incorporation (Taiwan, Province of China)
Inventor
Yu, Tu-Wen
Li, Jun-Sheng
Hsieh, Feng-Ching
Chen, Ching-Pei
Huang, Tsuei-Yin
Lu, Ying-Chen
Abstract
Lactobacillus isolates and their sub-cultured offspring can be used in the preparation of a variety of food products, and in the manufacture of pharmaceutical compositions for treating and/or alleviating diseases associated with inflammation, such as rheumatoid arthritis.
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
Lactobacillus paracasei when being administered or applied to a user can inhibit or reduce the number of pathogens of dental caries and periodontal diseases in oral cavity of the user, thereby achieving the efficacy of preventing dental diseases, such as dental caries and periodontal diseases.
A61K 8/96 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
C12N 1/12 - Unicellular algaeCulture media therefor
A61K 47/00 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient