In certain embodiments, a system includes a vitrectomy handpiece and a pneumatic assembly coupled to the vitrectomy handpiece. The vitrectomy handpiece includes a cutting assembly, and a diaphragm disposed in a drive chamber and coupled to the cutting assembly. The pneumatic assembly includes an airflow controlling member and an actuating assembly. The airflow controlling member is configured to direct air to the drive chamber to move the diaphragm, thereby actuating the cutting assembly. The actuating assembly is configured to actuate the airflow controlling member.
A drug delivery device includes a conveyor and a docking assembly movable by the conveyor to a plurality of patient stations. The docking assembly includes one or more imaging devices configured to have an eye of the patient in a field of view thereof. The docking assembly includes an injection assembly and a staging assembly including one or more actuators and configured to position the injection assembly relative to the eye of the patient. A controller is configured to receive one or more images from the one or more imaging devices; detect anatomy of the eye of the patient in the one or more images; and activate the one or more actuators to drive a needle mounted to the injection assembly into a placement location on the eye of the patient according to the location of the anatomy. A loader loads injection assemblies into the docking assembly.
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
A61G 15/12 - Rests specially adapted therefor, e.g. for the head or feet
A61M 5/42 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
A61B 34/20 - Surgical navigation systemsDevices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
Embodiments of the present disclosure generally relate to methods and processes for forming an ophthalmic product, such as contact lenses. More specifically, embodiments described herein relate to the production of contact lenses having a water-soluble phospholipid polymer disposed thereon, which may be released therefrom as an ophthalmic comfort agent during use of the contact lens. In some embodiments, a contact lens includes a bulk layer having a crosslinked polymeric material, and a poly(vinyl alcohol) (PVA) layer disposed on the bulk layer. The contact lens further includes a water-soluble phospholipid polymer disposed on the PVA layer. The water-soluble phospholipid polymer includes a plurality of phosphorylcholine units and a plurality of arylborono units.
G02B 1/04 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements made of organic materials, e.g. plastics
4.
STEREO ADAPTIVE OPTICS FOR RETINAL VISUALIZATION SYSTEM USING WAVEFRONT SENSING AND CORRECTION
A retina visualization system includes a laser device operable for outputting a primary laser beam, the laser device including a red, green, blue (RGB) diode array and an infrared (IR) diode, along with a stereo, confocal, biaxial microelectromechanical system (MEMS) scanning system. The scanning system receives the primary laser beam and outputs a scanning laser toward an eye along a visualization path. A Shack Hartmann wavefront sensor proximate the eye senses wavefront distortion in light reflected from the eye. A wavefront control device corrects the wavefront distortion in response to a control signal. A stereo pair of avalanche photodiode (APD) detectors detects light and generates an electronic signal in response thereto. An electronic control unit (ECU) transmits the control signal the wavefront control device to cause the wavefront control device to correct the wavefront distortion into a corrected wavefront, with corrected images displayed via a stereo display device.
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/12 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
A system includes an ophthalmic microscope configured to capture video of an ophthalmic treatment. A computer system is coupled to the ophthalmic microscope and is configured to: receive a first image from the ophthalmic microscope for a first wavelength band having a first width of less than 20 nanometers; receive a second image from the ophthalmic microscope for a second wavelength band having a second width of less than 20 nanometers; generate a vessel map of a retina of the eye of the patient according to the first image and the second image, the vessel map including representations of blood vessels of the retina; and display the vessel map on a display device. The computer system may further receive a reference image for an isosbestic wavelength band of oxygenated and de-oxygenated hemoglobin and generate the vessel map according to the reference image.
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/12 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
Intra-ocular lens (IOL) data describing an IOL model is processed using a machine learning model to obtain a selected calculator of a plurality of calculators that may be used to estimate the post-operative refractive error of the IOL model. The IOL data may be processed with patient data, such as eye measurements and patient history. Eye measurements may include anterior chamber depth (ACD) and white-to-white (WTW) distance. Patient history may include whether an eye has undergone past refractive error correction surgery. The selected calculator may be used to calculate a post-operative refractive error to guide selection of an IOL.
One or more images of an eye of a patient having an implanted IOL are received. The one or more images are captured using one or more imaging devices having one or more imaging modalities. A computing device determines misalignment of the IOL according to the one or more images and processes the misalignment using a predictive model to obtain an improvement probability. The computing device outputs an intervention recommendation according to the improvement probability. The intervention recommendation may be the result of cost/benefit analysis of the improvement probability.
In certain embodiments, a system includes a vitrectomy handpiece and a pneumatic assembly coupled to the vitrectomy handpiece. The vitrectomy handpiece includes a cutting assembly, and a diaphragm disposed in a drive chamber and coupled to the cutting assembly. The pneumatic assembly includes an airflow controlling member and an actuating assembly. The airflow controlling member is configured to direct air to the drive chamber to move the diaphragm, thereby actuating the cutting assembly. The actuating assembly is configured to actuate the airflow controlling member.
Embodiments disclosed herein provide an ophthalmic illumination device. The ophthalmic illumination device includes a first optical fiber having a proximal end and a distal end, and a second optical fiber having a proximal end and a distal end. The proximal end of the first optical fiber is coupled to a light source that provides an illumination light, and the distal end of the first optical fiber is disposed within a first ferrule. The proximal end of the second optical fiber is disposed within a second ferrule, and the distal end of the second optical fiber is configured to transmit the illumination light received from the first optical fiber into an interior portion of a patient's eye. The first ferrule is disposed against the second ferrule to couple the distal end of the first optical fiber with the proximal end of the second optical fiber.
In certain embodiments, an ophthalmic injection robot includes a frame, a robotic arm, a docking assembly, and a control system. The frame includes a patient support and positioning cameras. The docking assembly is coupled to the robotic arm, and includes fine adjustment cameras, and a staging assembly including fine adjustment actuators, a needle extension actuator, and a needle assembly including a needle. The control system includes a memory and a processor configured to receive the fine adjustment image data generated by fine adjustment cameras, process the fine adjustment image data to generate a blood vessel map of an eye of a patient, select an injection site on the eye of the patient based on the blood vessel map, and control the fine adjustment actuators to position the needle above the selected injection site for target-confirmed injection of a drug through the needle and into the eye of the patient.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61M 5/42 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
11.
EMBEDDED CONTACT LENSES WITH SURFACE AND ASTIGMATISM MASKING
In general, embodiments of the present disclosure relate to pigment containing contact lenses (100), such as colored contact lenses. In particular, embodiments of the present disclosure relate to a hybrid hard-soft silicone hydrogel contact lens (100). In at least some embodiments, a method for forming a contact lens (100) is provided. The method includes printing a pigmented layer (106) on a lens mold including an optic zone (207) and curing the pigmented layer (106) with ultraviolet (UV) light. The pigmented layer (106) is printed outside an outer boundary of the optic zone (207) of the lens mold. The method further includes forming an insert lens layer (104), the insert lens layer disposed on the cured pigmented layer (106), curing the insert lens layer (104) to form an insert lens (310) having a modulus of greater than about 2 MPa, suspending the insert lens (310) in a lens-forming material (108) and curing the lens-forming material (108) to form a lens body (100).
Embodiments disclosed herein provide a system for controlling laser transmission during an ophthalmic procedure. The system includes first and second laser sources, an optical fiber, and a signal detector. The first and second laser sources are configured to respectively generate first and second laser beams. The optical fiber is configured to receive the first and second laser beams from the first and second laser sources, transmit the first and second laser beams from a distal end of the optical fiber, receive a reflected portion of the second laser beam, and direct the reflected portion to the signal detector. The signal detector is configured to receive the reflected portion from the optical fiber, and generate a signal detector output based on the reflected portion. The signal detector output is indicative of a presence or an absence of a bubble or vapor at the distal end of the optical fiber.
Certain aspects of the present disclosure provide systems and methods for monitoring usage of reusable surgical devices. In certain embodiments, an apparatus includes a housing defining an external reader surface, and a wireless reader comprising an antenna disposed within the housing. Within a bandwidth of the antenna, a majority of a radiation pattern of the antenna extends through the external reader surface. The apparatus further includes a reflector disposed near the antenna opposite the external reader surface. The reflector is configured to reorient a portion of the radiation pattern as a reflected portion that extends through the external reader surface.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
Materials and methods of manufacturing intraocular lenses, including polymeric materials for the intraocular lenses, fluids for intraocular lenses, and adhesives for intraocular lenses. The intraocular lenses can include an optic portion and a peripheral region in fluid communication.
C09J 4/00 - Adhesives based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond
C09J 4/06 - Adhesives based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond in combination with a macromolecular compound other than an unsaturated polymer of groups
G02C 7/08 - Auxiliary lensesArrangements for varying focal length
An apparatus that can be used to fold an intraocular lens or other implant before inserting it into an eye in various locations using variable surgical techniques. Some embodiments may comprise or consist essentially of a haptic folding mechanism configured to fold one or more haptics onto the top of an optic prior to the optic being folded into a nozzle. In some embodiments, a leading haptic lifter or lifting mechanism can be configured to raise and constrain a leading haptic during implant delivery. This leading haptic folding mechanism can actively lift the leading haptic onto the top of the optic.
In certain embodiments, a robotic system for an ophthalmic injection facility includes one or more patient transportation robots and an ophthalmic injection robot located in a treatment hub of the ophthalmic injection facility. Each patient transportation robot includes a drive system, one or more sensors, a patient interface (PI) system, a chair, and a control system configured to navigate to the treatment hub based on the sensor data. The ophthalmic injection robot includes a support frame, a robotic arm, and a control system. The robotic arm includes one or more cameras and a docking assembly including a needle. The control system is configured to position the docking assembly to couple the docking assembly to a PI device attached to an eye of the patient, inject a drug through the needle into the eye of the patient, and position the docking assembly to decouple the docking assembly from the PI device.
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
In certain embodiments, a method of controlling a light engine of an illumination system includes receiving, from a user input device, a desired color and a desired total flux output of a light engine; obtaining color signature data for each light emitting diode (LED) of the light engine; obtaining power flux data for each LED of the light engine; determining a power command for each LED based on the color signature data for each LED, the power flux data for each LED, the desired color, and the desired total flux output; and sending each power command to the LED to generate the desired color and the desired total flux output from the light engine. In certain embodiments, the light engine may include a red LED, a green LED, and a blue LED.
Embodiments disclosed herein provide an ophthalmic illumination device. The ophthalmic illumination device includes a first optical fiber having a proximal end and a distal end, and a second optical fiber having a proximal end and a distal end. The proximal end of the first optical fiber is coupled to a light source that provides an illumination light, and the distal end of the first optical fiber is disposed within a first ferrule. The proximal end of the second optical fiber is disposed within a second ferrule, and the distal end of the second optical fiber is configured to transmit the illumination light received from the first optical fiber into an interior portion of a patient’s eye. The first ferrule is disposed against the second ferrule to couple the distal end of the first optical fiber with the proximal end of the second optical fiber.
A system includes an ophthalmic microscope configured to capture video of an ophthalmic treatment. A computer system is coupled to the ophthalmic microscope and is configured to: receive a first image from the ophthalmic microscope for a first wavelength band having a first width of less than 20 nanometers; receive a second image from the ophthalmic microscope for a second wavelength band having a second width of less than 20 nanometers; generate a vessel map of a retina of the eye of the patient according to the first image and the second image, the vessel map including representations of blood vessels of the retina; and display the vessel map on a display device. The computer system may further receive a reference image for an isosbestic wavelength band of oxygenated and de-oxygenated hemoglobin and generate the vessel map according to the reference image.
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
Intra-ocular lens (IOL) data describing an IOL model is processed using a machine learning model to obtain a selected calculator of a plurality of calculators that may be used to estimate the post-operative refractive error of the IOL model. The IOL data may be processed with patient data, such as eye measurements and patient history. Eye measurements may include anterior chamber depth (ACD) and white-to-white (WTW) distance. Patient history may include whether an eye has undergone past refractive error correction surgery. The selected calculator may be used to calculate a post-operative refractive error to guide selection of an IOL.
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/103 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining refraction, e.g. refractometers, skiascopes
A computer-implemented method of resource-efficient consent management. Embodiments include receiving, at a device, an indication that consent has been given with respect to one or more items. Embodiments include determining, at the device, a binary bit pattern representative of the indication based on a configured association between the one or more items and one or more values in the binary bit pattern. Embodiments include storing, at the device, a memorialization of the indication via a bit vector having the binary bit pattern.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
In certain embodiments, a robotic system for a surgical facility includes a dispenser, a delivery robot, and a setup robot located in an operating room. The delivery robot includes a drive system, sensors, a robotic arm including a camera and a gripper, and a control system that is configured to navigate to the dispenser based on sensor data, retrieve a bin containing a surgical package from the dispenser, navigate to a storage table in the operating room based on the sensor data, and deliver the packages to the storage table. The setup robot includes a robotic arm including first and second end effectors, and a control system that is configured to open the surgical package located on the storage table, remove items from the surgical package, and deposit the items on a sterile tray in the operating room.
In general, embodiments of the present disclosure relate to pigment containing contact lenses, such as colored contact lenses. In particular, embodiments of the present disclosure relate to a hybrid hard-soft silicone hydrogel contact lens. In at least some embodiments, a method for forming a contact lens is provided. The method includes printing a pigmented layer on a lens mold including an optic zone and curing the pigmented layer with ultraviolet (UV) light. The pigmented layer is printed outside an outer boundary of the optic zone of the lens mold. The method further includes forming an insert lens layer, the insert lens layer disposed on the cured pigmented layer, curing the insert lens layer to form an insert lens having a modulus of greater than about 2 MPa, suspending the insert lens in a lens-forming material and curing the lens-forming material to form a lens body.
A computer-implemented method of automated dosing optimization for photo-bio- modulation (PBM) treatment. Embodiments include a light source of a multi-spectral imaging device configured to generate outgoing light across a range of wavelengths, one or more filters of the multi-spectral imaging device configured to generate incoming light to allow only a subset of wavelengths from the range of wavelengths to pass through, and one or more sensors of the multi-spectral imaging device configured to detect the filtered incoming light. Embodiments include one or more processors configured to execute instructions that cause the system to generate, based on the detecting of the filtered incoming light, a set of multi-spectral images of an eye of a patient, and generate, based on the set of multi-spectral images and one or more attributes of the patient, a PBM dosing regimen for the patient.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
27.
OPTHALMIC STRUCTURE MODELING BASED EYE REGISTRATION
The present disclosure relates to operations that include generating, based on a first image of a first depiction of an eye in a first dilation state and a second image of a second depiction of the eye in a second dilation state, a third depiction of the eye in the second dilation state. Further, the operations may include determining an alignment registration between the first depiction of the eye and the second depiction of the eye based on a comparison between the second depiction and the third depiction.
G06T 7/33 - Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods
A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
G06V 40/18 - Eye characteristics, e.g. of the iris
28.
METHOD FOR DETERMINING THE INVERSION STATE OF A SOFT CONTACT LENS
A method for determining the inversion state of a soft contact lens which is arranged in an interior space of an inspection cuvette comprises the steps of: through the viewing glass obtaining a dark-field image of the soft contact lens arranged in the interior space along the optical axis; identifying a lens edge of the soft contact lens in the dark-field image; determining one characteristic values representative of the brightness of a portion of the lens edge in the dark-field image; comparing one of the characteristic values with a corresponding predetermined threshold value; and determining that the soft contact lens is inverted in case the characteristic values is equal to or above the corresponding predetermined threshold value.
In certain embodiments, a robotic system for performing cataract surgery includes a base, a robotic mechanism, and a control system. The robotic mechanism includes a patient interface configured to be coupled to the head of a patient, an end effector configured to receive an exchangeable tool, and sensors that include a polarization camera, a stereo camera, and an optical coherence tomography (OCT) sensor. The control system includes a processor configured to fuse the polarized image data, the stereo image data, and the depth image data to generate fused sensor data of a region of the eye including the cornea and the lens, determine the location of a phacoemulsification tool coupled to the end effector based on the fused sensor data, and control the end effector and the phacoemulsification tool, based on the phacoemulsification tool location, to remove the lens through an incision in the cornea.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A drug delivery device includes a conveyor and a docking assembly movable by the conveyor to a plurality of patient stations. The docking assembly includes one or more imaging devices configured to have an eye of the patient in a field of view thereof. The docking assembly includes an injection assembly and a staging assembly including one or more actuators and configured to position the injection assembly relative to the eye of the patient. A controller is configured to receive one or more images from the one or more imaging devices; detect anatomy of the eye of the patient in the one or more images; and activate the one or more actuators to drive a needle mounted to the injection assembly into a placement location on the eye of the patient according to the location of the anatomy. A loader loads injection assemblies into the docking assembly.
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
A wide-angle viewing system (WAVS) for an ophthalmic microscope is provided. The WAVS includes a frame, a reduction lens module attached to the frame, and an image inverter-reverter module movably coupled to the frame. The reduction lens module includes an ophthalmic microscope mount, and a movable reduction lens assembly with an optical axis, a disengaged position, and an engaged position. The image inverter-reverter module includes an optical prism and a loupe lens assembly. The image inverter-reverter module has an optical axis, a stowed position, and a deployed position. When the movable reduction lens assembly is disposed in the engaged position, the optical axis of the movable reduction lens assembly is aligned with the optical axis of the ophthalmic microscope. When the image inverter-reverter module is disposed in the deployed position, the optical axis of the image inverter-reverter module is aligned with the optical axis of the ophthalmic microscope.
One or more images of an eye of a patient having an implanted IOL are received. The one or more images are captured using one or more imaging devices having one or more imaging modalities. A computing device determines misalignment of the IOL according to the one or more images and processes the misalignment using a predictive model to obtain an improvement probability. The computing device outputs an intervention recommendation according to the improvement probability. The intervention recommendation may be the result of cost/benefit analysis of the improvement probability.
A61B 3/18 - Arrangement of plural eye-testing or -examining apparatus
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/103 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining refraction, e.g. refractometers, skiascopes
A61B 3/107 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining the shape or measuring the curvature of the cornea
An ophthalmic surgical system includes a biomechanical imaging device configured to perform measurements of an eye of a patient. The system further includes a controller configured to: receive Brillouin light scattering (BLS) data from the BLS imaging device; calculate material properties according to the BLS data; select a tissue type according to the material properties; and generating an output corresponding to the tissue type. The biomechanical imaging device may include a confocal Brillouin microscope or a BLS spectrometer and a light source coupled to a fiber optic probe. Tissue types may include a retinal membrane, type of retinal membrane, or membrane-free area of the retina.
A retina visualization system includes a laser device operable for outputting a primary laser beam, the laser device including a red, green, blue (RGB) diode array and an infrared (IR) diode, along with a stereo, confocal, biaxial microelectromechanical system (MEMS) scanning system. The scanning system receives the primary laser beam and outputs a scanning laser toward an eye along a visualization path. A Shack Hartmann wavefront sensor proximate the eye senses wavefront distortion in light reflected from the eye. A wavefront control device corrects the wavefront distortion in response to a control signal. A stereo pair of avalanche photodiode (APD) detectors detects light and generates an electronic signal in response thereto. An electronic control unit (ECU) transmits the control signal the wavefront control device to cause the wavefront control device to correct the wavefront distortion into a corrected wavefront, with corrected images displayed via a stereo display device.
In certain embodiments, a robotic system for performing cataract surgery includes a base, a robotic mechanism, and a control system. The robotic mechanism includes a patient interface configured to be coupled to the head of a patient, an end effector configured to receive an exchangeable tool, and sensors that include a polarization camera, a stereo camera, and an optical coherence tomography (OCT) sensor. The control system includes a processor configured to fuse the polarized image data, the stereo image data, and the depth image data to generate fused sensor data of a region of the eye including the cornea and the lens, determine the location of a phacoemulsification tool coupled to the end effector based on the fused sensor data, and control the end effector and the phacoemulsification tool, based on the phacoemulsification tool location, to remove the lens through an incision in the cornea.
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
G06T 5/50 - Image enhancement or restoration using two or more images, e.g. averaging or subtraction
In certain embodiments, a robotic system for an ophthalmic injection facility includes one or more patient transportation robots and an ophthalmic injection robot located in a treatment hub of the ophthalmic injection facility. Each patient transportation robot includes a drive system, one or more sensors, a patient interface (PI) system, a chair, and a control system configured to navigate to the treatment hub based on the sensor data. The ophthalmic injection robot includes a support frame, a robotic arm, and a control system. The robotic arm includes one or more cameras and a docking assembly including a needle. The control system is configured to position the docking assembly to couple the docking assembly to a PI device attached to an eye of the patient, inject a drug through the needle into the eye of the patient, and position the docking assembly to decouple the docking assembly from the PI device.
A61G 5/04 - Chairs or personal conveyances specially adapted for patients or disabled persons, e.g. wheelchairs motor-driven
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
Embodiments of the present disclosure generally relate to methods and processes for forming an ophthalmic product, such as contact lenses. More specifically, embodiments described herein relate to the production of contact lenses having a water-soluble phospholipid polymer disposed thereon, which may be released therefrom as an ophthalmic comfort agent during use of the contact lens. In some embodiments, a contact lens includes a bulk layer having a crosslinked polymeric material, and a poly(vinyl alcohol) (PVA) layer disposed on the bulk layer. The contact lens further includes a water-soluble phospholipid polymer disposed on the PVA layer. The water-soluble phospholipid polymer includes a plurality of phosphorylcholine units and a plurality of arylborono units.
G02B 1/04 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements made of organic materials, e.g. plastics
B65B 17/00 - Other machines, apparatus, or methods for packaging articles or materials
An ophthalmic surgical instrument for peeling a retinal membrane includes a handle and an actuator mounted on the handle. An outer tube is mounted to the handle and an inner rod extends within the outer tube. A grasping structure is secured to a distal end of the inner rod having first and second polymer arms secured to the inner rod. Each of the first polymer arm and the second polymer arms has a distal end that is angled to conform to the retinal membrane. The actuator is configured to control relative position of the inner rod and the outer tube in order to extend the grasping structure out of the outer tube and withdraw the grasping structure within the outer tube.
A wide-angle viewing system (WAVS) for an ophthalmic microscope is provided. The WAVS includes a frame, a reduction lens module attached to the frame, and an image inverter-reverter module movably coupled to the frame. The reduction lens module includes an ophthalmic microscope mount, and a movable reduction lens assembly with an optical axis, a disengaged position, and an engaged position. The image inverter-reverter module includes an optical prism and a loupe lens assembly. The image inverter-reverter module has an optical axis, a stowed position, and a deployed position. When the movable reduction lens assembly is disposed in the engaged position, the optical axis of the movable reduction lens assembly is aligned with the optical axis of the ophthalmic microscope. When the image inverter-reverter module is disposed in the deployed position, the optical axis of the image inverter-reverter module is aligned with the optical axis of the ophthalmic microscope.
In certain embodiments, a method of controlling a light engine of an illumination system includes receiving, from a user input device, a desired color and a desired total flux output of a light engine; obtaining color signature data for each light emitting diode (LED) of the light engine; obtaining power flux data for each LED of the light engine; determining a power command for each LED based on the color signature data for each LED, the power flux data for each LED, the desired color, and the desired total flux output; and sending each power command to the LED to generate the desired color and the desired total flux output from the light engine. In certain embodiments, the light engine may include a red LED, a green LED, and a blue LED.
An ophthalmic surgical system includes a biomechanical imaging device configured to perform measurements of an eye of a patient. The system further includes a controller configured to: receive Brillouin light scattering (BLS) data from the BLS imaging device; calculate material properties according to the BLS data; select a tissue type according to the material properties; and generating an output corresponding to the tissue type. The biomechanical imaging device may include a confocal Brillouin microscope or a BLS spectrometer and a light source coupled to a fiber optic probe. Tissue types may include a retinal membrane, type of retinal membrane, or membrane-free area of the retina.
A61B 3/12 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
An ophthalmic surgical system includes an item of ophthalmic surgical equipment and one or more computing devices. The one or more computing devices are configured to receive a three-dimensional image of an eye of a patient; process the three-dimensional image using a machine learning model to obtain a density map of a crystalline lens of the eye of the patient; and control the item of surgical equipment according to the density map. The item of surgical equipment may be a treatment laser or phaco-vit tool. Aspiration pressure of the phaco-vit tool may be controlled based on a position of a distal end of the phaco-vit tool and a corresponding density in the density map.
A computer-implemented method of resource-efficient consent management. Embodiments include receiving, at a device, an indication that consent has been given with respect to one or more items. Embodiments include determining, at the device, a binary bit pattern representative of the indication based on a configured association between the one or more items and one or more values in the binary bit pattern. Embodiments include storing, at the device, a memorialization of the indication via a bit vector having the binary bit pattern.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
An ophthalmic surgical system includes an item of ophthalmic surgical equipment and one or more computing devices. The one or more computing devices are configured to receive a three-dimensional image of an eye of a patient; process the three-dimensional image using a machine learning model to obtain a density map of a crystalline lens of the eye of the patient; and control the item of surgical equipment according to the density map. The item of surgical equipment may be a treatment laser or phaco-vit tool. Aspiration pressure of the phaco-vit tool may be controlled based on a position of a distal end of the phaco-vit tool and a corresponding density in the density map.
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/12 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
A61B 34/20 - Surgical navigation systemsDevices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A61B 17/00 - Surgical instruments, devices or methods
In certain embodiments, a system configured to illuminate an eye includes a pattern illuminator and an illuminator computer. The pattern illuminator provides an illumination pattern directed towards the anterior surface of the eye. The anterior surface of the eye reflects the illumination pattern as a reflected illumination pattern. The illuminator computer receives, via a wireless communication link, a set of instructions configured to coordinate the illumination pattern with a device of one or more devices of an ophthalmic system. The illuminator computer instructs the pattern illuminator to provide the illumination pattern according to the set of instructions to coordinate the illumination pattern with the device of the ophthalmic system.
A computer-implemented method of automated dosing optimization for photo-bio- modulation (PBM) treatment. Embodiments include a light source of a multi-spectral imaging device configured to generate outgoing light across a range of wavelengths, one or more filters of the multi-spectral imaging device configured to generate incoming light to allow only a subset of wavelengths from the range of wavelengths to pass through, and one or more sensors of the multi- spectral imaging device configured to detect the filtered incoming light. Embodiments include one or more processors configured to execute instructions that cause the system to generate, based on the detecting of the filtered incoming light, a set of multi-spectral images of an eye of a patient, and generate, based on the set of multi-spectral images and one or more attributes of the patient, a PBM dosing regimen for the patient.
The present disclosure relates to operations that include generating, based on a first image of a first depiction of an eye in a first dilation state and a second image of a second depiction of the eye in a second dilation state, a third depiction of the eye in the second dilation state. Further, the operations may include determining an alignment registration between the first depiction of the eye and the second depiction of the eye based on a comparison between the second depiction and the third depiction.
A method for determining the inversion state of a soft contact lens which is arranged in an interior space of an inspection cuvette comprises the steps of: through the viewing glass obtaining a dark-field image of the soft contact lens arranged in the interior space along the optical axis; identifying a lens edge of the soft contact lens in the dark-field image; determining one characteristic values representative of the brightness of a portion of the lens edge in the dark-field image; comparing one of the characteristic values with a corresponding predetermined threshold value; and determining that the soft contact lens is inverted in case the characteristic values is equal to or above the corresponding predetermined threshold value.
In certain embodiments, an ophthalmic system and computer-implemented method for automatically initializing an image guided surgery are described. The initialization includes monitoring a scene using multiple images captured by a first imaging device. An eye of a user is detected within a first image of the multiple images. In response to detecting the eye of the user, a registration procedure is initiated with the first image and a reference image of the eye of the user to generate a set of transformation information. A set of overlay content is generated based on the set of transformation information. The set of overlay content includes a transformed first image or a transformed reference image. Overlay content is presented onto the scene via a second imaging device.
Provided herein are topical ophthalmic pharmaceutical compositions of (1R,2S,5R)-2-isopropyl-N-(4- methoxyphenyl)-5-methylcyclohexane-1-carboxamide (WS-12, acoltremon) in LDPE containers, their methods of manufacture, and uses thereof in ocular therapeutics.
In certain embodiments, a system configured to illuminate an eye includes a pattern illuminator and an illuminator computer. The pattern illuminator provides an illumination pattern directed towards the anterior surface of the eye. The anterior surface of the eye reflects the illumination pattern as a reflected illumination pattern. The illuminator computer receives, via a wireless communication link, a set of instructions configured to coordinate the illumination pattern with a device of one or more devices of an ophthalmic system. The illuminator computer instructs the pattern illuminator to provide the illumination pattern according to the set of instructions to coordinate the illumination pattern with the device of the ophthalmic system.
Provided herein are topical ophthalmic pharmaceutical compositions of (1R,2S,5R)-2-isopropyl-N-(4-methoxyphenyl)-5-methylcyclohexane-1-carboxamide (WS-12, acoltremon) in LDPE containers, their methods of manufacture, and uses thereof in ocular therapeutics.
A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
In certain embodiments, an ophthalmic laser surgical system for treating a floater in a vitreous of an eye includes a floater detection system, a laser device, and a computer. The floater detection system determines the location of the floater in the vitreous of the eye. The laser device directs a laser beam along a laser beam path towards the floater. The computer accesses a three-dimensional scan pattern for the laser beam that yields a three-dimensional pulse pattern of laser pulses. The three-dimensional pulse pattern has a bubble shield pulse pattern at the posterior side of the three-dimensional pulse pattern. The bubble shield pulse pattern forms a bubble shield that reduces laser radiation exposure at a retina of the eye. The computer instructs the laser device to direct the laser beam towards the floater according to the three-dimensional scan pattern.
A61F 9/008 - Methods or devices for eye surgery using laser
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 18/20 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
62.
MULTIFOCAL DIFFRACTIVE INTRAOCULAR LENS WITH IMPROVED DESIGN FREEDOM
An ophthalmic lens includes a diffractive structure having a plurality of echelettes. The diffractive structure is configured to provide diffracted optical energy distributions for one or more desired optical powers. At least one echelette is arranged at a radial distance from an optical axis of the ophthalmic lens such that radii of the plurality of echelettes are non-periodic. At least one echelette has a transition region connecting the at least one echelette to an adjacent echelette such that the transition region is limited to an affine power function. The diffractive structure is configured to provide first, second, and third optical energy distributions corresponding to distance, intermediate, and near vision, respectively. Advantageously the ophthalmic lens provides improved design freedom (e.g., non-periodic echelette radii, affine power transition regions), custom powers (e.g., non-integer multiples), improved optical performance (e.g., high energy utilization, MTF, and visual quality), and reduced visual disturbances (e.g., low halo effect).
An ophthalmic lens includes a diffractive structure having a plurality of echelettes. The diffractive structure is configured to provide diffracted optical energy distributions for one or more desired optical powers. At least one echelette is arranged at a radial distance from an optical axis of the ophthalmic lens such that radii of the plurality of echelettes are non-periodic. At least one echelette has a transition region connecting the at least one echelette to an adjacent echelette such that the transition region is limited to an affine power function. The diffractive structure is configured to provide first, second, and third optical energy distributions corresponding to distance, intermediate, and near vision, respectively. Advantageously the ophthalmic lens provides improved design freedom (e.g., non-periodic echelette radii, affine power transition regions), custom powers (e.g., non-integer multiples), improved optical performance (e.g., high energy utilization, MTF, and visual quality), and reduced visual disturbances (e.g., low halo effect).
In some embodiments, an optical device includes a bulk silicone hydrogel material having a convex anterior surface and an opposite concave posterior surface, a central optical zone, and one or more peripheral zones circumscribing the central optical zone. The contact lens includes an insert embedded in the bulk silicone hydrogel material having a convex anterior surface and an opposite concave posterior surface, the convex anterior surface comprising 10 or more echelettes. The optical device has a convex anterior surface and an opposite concave posterior surface. The insert includes a crosslinked silicone-containing vinyl copolymer different from a crosslinked silicone-containing vinyl copolymer of the bulk silicone hydrogel material and has a diameter up to about 10 mm. The insert is concentric with a central axis of the optical device.
In general, embodiments of the present disclosure relate to pigment containing contact lenses, such as colored contact lenses. In particular, embodiments of the present disclosure relate to a silicon hydrogel (SiHy) contact lens having a layered configuration that completely encapsulates a layer of pigment. In at least some embodiments, a method for forming a contact lens is provided. The method includes applying a clear ink to at least an iris portion of a mold and curing the clear ink with UV light to form a clear ink layer. The clear ink includes about 38 wt% to about 70 wt% of a polymer binder. The method further includes, applying, via pad printing, at least one pigmented layer onto the cured clear ink layer, and curing the at least one pigmented layer with UV light to form a lens assembly.
ACCOMMODATING INTRAOCULAR LENSES WITH PHASE SHIFTING LENS SURFACE PROFILE, INTRAOCULAR LENSES WITH MECHANICAL ACCOMMODATING STRUCTURE, AND METHODS OF USE THEREOF
Disclosed are accommodating intraocular lenses with a phase shifting lens surface profile, intraocular lenses with a mechanical accommodating structure, and methods of use thereof. For example, an intraocular lens is disclosed comprising an optic portion comprising an anterior lens and a posterior lens and an accommodating mechanical structure coupled to the optic portion. The anterior lens can comprise a phase shifting lens surface profile. The mechanical accommodating structure can comprise a plurality of compressible haptics. Each of the compressible haptics can be shaped as an annulus sector and can comprise a fluted or plicated portion configured to allow the haptics to compress or expand.
A method for treating near-retina floaters includes dilating a pupil of an eye of a patient to at least 6.6 millimeters (mm). While the pupil is dilated to at least 6.6 mm, the method further includes emitting, by an optical delivery system, a plurality of pulses from a treatment laser into the eye of the patient, each pulse of the plurality of pulses having a diameter upon passing through the pupil that substantially fills the pupil and having a focus within 3 mm of a retina of the eye of the patient. Pulses may pass through adaptive optics that may be adjusted based on light emitted from the eye, such as two-photon fluorescence or second harmonic radiation, in order to reduce spot size at the focus.
In general, embodiments of the present disclosure relate to pigment containing contact lenses, such as colored contact lenses. In particular, embodiments of the present disclosure relate to a silicon hydrogel (SiHy) contact lens having a layered configuration that completely encapsulates a layer of pigment. In at least some embodiments, a method for forming a contact lens is provided. The method includes applying a clear ink to at least an iris portion of a mold and curing the clear ink with UV light to form a clear ink layer. The clear ink includes about 38 wt % to about 70 wt % of a polymer binder. The method further includes, applying, via pad printing, at least one pigmented layer onto the cured clear ink layer, and curing the at least one pigmented layer with UV light to form a lens assembly.
B29D 11/00 - Producing optical elements, e.g. lenses or prisms
G02B 1/04 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements made of organic materials, e.g. plastics
The present disclosure generally relates to surgical instruments for ophthalmic surgical procedures, and more specifically, surgical instruments that are capable of providing femtosecond laser pulses. In some aspects, a surgical instrument includes a body and a power amplifier disposed within the body. The power amplifier is configured to receive laser pulses from a laser source external to the body, and to deliver amplified laser pulses to an optical fiber extending toward a distal end of the body. The surgical instrument further includes an optical element disposed near the distal end. The optical element is configured to focus the amplified laser pulses.
A system and method of automatic cataract grading uses an optical coherence tomography ("OCT") device to generate three-dimensional OCT data of a lens. The system includes a controller having at least one processor and at least one non-transitory, tangible memory on which instructions are recorded. The controller is configured to divide the lens into a plurality of regions, and define segmentation lines for the plurality of regions based in part on predetermined reference values. The controller is configured to adjust the segmentation lines to fit respective areas adjacent to the plurality of regions, the respective areas having a relatively high gradient value. A respective mean opacity for the plurality of regions is determined based on the volumetric OCT data. The controller is configured to generate a cataract distribution trace of the lens based on the respective mean opacity in the plurality of regions.
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/117 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes
Medical and surgical apparatus and instruments for
ophthalmology; ophthalmic lenses, including intraocular
lenses and contact lenses, as well as accessories for the
aforementioned products, insofar as they are not included in
other classes; eyeglasses and contact lenses.
Medical and surgical apparatus and instruments for
ophthalmology; ophthalmic lenses, including intraocular
lenses and contact lenses, as well as accessories for the
aforementioned products, insofar as they are not included in
other classes; eyeglasses and contact lenses.
In some embodiments, an optical device includes a bulk silicone hydrogel material having a convex anterior surface and an opposite concave posterior surface, a central optical zone, and one or more peripheral zones circumscribing the central optical zone. The contact lens includes an insert embedded in the bulk silicone hydrogel material having a convex anterior surface and an opposite concave posterior surface, the convex anterior surface comprising 10 or more echelettes. The optical device has a convex anterior surface and an opposite concave posterior surface. The insert includes a crosslinked silicone-containing vinyl copolymer different from a crosslinked silicone-containing vinyl copolymer of the bulk silicone hydrogel material and has a diameter up to about 10 mm. The insert is concentric with a central axis of the optical device.
An ophthalmic surgical system for monitoring incision performance includes a laser device, a camera, and a computer. laser device delivers a laser beam with a laser setting energy towards a target to create optical breakdowns in the target. The camera generates images of the optical breakdowns in the target. The computer instructs the laser device to create the optical breakdowns in the target to yield a test pattern. The test pattern comprises regions of optical breakdowns, where each region was created with a different laser setting energy. From the images, the computer identifies a lowest energy region with substantially continuous optical breakdowns, and designates the laser setting energy used to create the identified region as a threshold energy.
A method for treating near-retina floaters includes dilating a pupil of an eye of a patient to at least 6.6 millimeters (mm). While the pupil is dilated to at least 6.6 mm, the method further includes emitting, by an optical delivery system, a plurality of pulses from a treatment laser into the eye of the patient, each pulse of the plurality of pulses having a diameter upon passing through the pupil that substantially fills the pupil and having a focus within 3 mm of a retina of the eye of the patient. Pulses may pass through adaptive optics that may be adjusted based on light emitted from the eye, such as two-photon fluorescence or second harmonic radiation, in order to reduce spot size at the focus.
A surgical instrument includes a tube and a horn. The tube has a distal end and a proximal end. A loop is formed with a cable that is folded between a first end of the cable and a second end of the cable. The cable is at least partially disposed in the tube. The horn is configured to oscillate. The first end of the cable is coupled to the horn. An oscillation of the horn actuates the cable.
ACCOMMODATING INTRAOCULAR LENSES WITH PHASE SHIFTING LENS SURFACE PROFILE, INTRAOCULAR LENSES WITH MECHANICAL ACCOMMODATING STRUCTURE, AND METHODS OF USE THEREOF
Disclosed are accommodating intraocular lenses with a phase shifting lens surface profile, intraocular lenses with a mechanical accommodating structure, and methods of use thereof. For example, an intraocular lens is disclosed comprising an optic portion comprising an anterior lens (108) and a posterior lens (110) and an accommodating mechanical structure (104) coupled to the optic portion. The anterior lens can comprise a phase shifting lens surface profile. The mechanical accommodating structure can comprise a plurality of compressible haptics. Each of the compressible haptics can be shaped as an annulus sector and can comprise a fluted or plicated portion configured to allow the haptics to compress or expand.
In some embodiments, a vitrectomy probe may include an inner cutting tube reciprocating in an outer tube. The outer tube includes a side port and the inner tube includes a distal cutting port, and, in some embodiments, an additional side port. In some embodiments, the inner tube may also include a flat upper edge that cuts across the outer tube side port. In some embodiments, a diaphragm drives the inner tube and may have an open-stroke side with a lower hardness material than a closed-stroke side. In some embodiments, an aspiration tube coupled to the vitrectomy probe may include a first aspiration tubing and a second aspiration tubing with a lower hardness than the first aspiration tubing. In some embodiments, the vitrectomy probe may be coupled to pneumatic tubing that is stepped or tapered.
An ophthalmic laser surgical system for treating an eye includes a laser device, one or more cameras, and a computer. The eye has anatomical features, including the cornea with the anterior corneal surface. The laser device directs a laser beam towards the eye. A camera generates images of the anatomical features, including the anterior corneal surface. The computer facilitates docking a patient interface onto the eye by accessing eye information describing the eye. The eye information comprises an eye model describing the anatomical features. The computer determines from the eye model the predicted corneal surface position when the eye is aligned to dock the patient interface onto the eye. The computer detects from the images the actual corneal surface position prior to docking the patient interface onto the eye, and compares the predicted corneal surface position with the actual corneal surface position to detect misalignment.
A61F 9/008 - Methods or devices for eye surgery using laser
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
85.
SYSTEMS AND METHODS FOR ASSESSING LENS DYSFUNCTION
A method includes measuring an eye of a patient according to a plurality of imaging modalities to obtain a plurality of measurements, such as an OCT image, aberrometer measurement, or visible light image. The measurements are processed to obtain a characterization of lens scattering and a characterization of lens accommodation. A dysfunctional lens syndrome score is calculated for the lens according to the characterizations of lens scattering and accommodation and the dysfunctional lens syndrome score is output.
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/117 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes
A61B 3/103 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining refraction, e.g. refractometers, skiascopes
86.
MAGNETIC CONTROLLED VALVE WITH ADJUSTABLE SEALING REGION
In some embodiments, a dispensing plug includes a fluid path having an inlet and an outlet. The dispensing plug also includes a valve (222) adjustably disposed relative to the fluid path. The valve (222) includes a first valve portion (342) positioned in the fluid path between the inlet and the outlet. The valve also includes a second valve portion (239) oriented to cause a first force to be exerted on the first valve portion (342). The first force biases the first valve portion (342) toward closure of the fluid path.
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
B65D 47/18 - Closures with discharging devices other than pumps with pouring spouts or tubesClosures with discharging devices other than pumps with discharge nozzles or passages for discharging dropsDroppers
87.
METHODS FOR USING VIOLET LASER ENERGY TO ADJUST THE REFRACTIVE PROPERTIES OF IMPLANTED INTRAOCULAR LENSES
Described herein is a method for adjusting at least one optical characteristic of an intraocular lens. The method involves the use of a violet laser having a wavelength in the range of 380 nm to 460 nm. The violet laser can be used to correct post-operative refractive errors in intraocular lenses, while being noninvasive and safe.
The present disclosure generally relates to surgical instruments for ophthalmic surgical procedures, and more specifically, surgical instruments that are capable of providing femtosecond laser pulses. In some aspects, a surgical instrument includes a body and a power amplifier disposed within the body. The power amplifier is configured to receive laser pulses from a laser source external to the body, and to deliver amplified laser pulses to an optical fiber extending toward a distal end of the body. The surgical instrument further includes an optical element disposed near the distal end. The optical element is configured to focus the amplified laser pulses.
H01S 3/0933 - Processes or apparatus for excitation, e.g. pumping using optical pumping by incoherent light of a semiconductor, e.g. light emitting diode
89.
AUTOMATIC CATARACT GRADING BASED ON THREE-DIMENSIONAL OPTICAL COHERENCE TOMOGRAPHY
A system and method of automatic cataract grading uses an optical coherence tomography (“OCT”) device to generate three-dimensional OCT data of a lens. The system includes a controller having at least one processor and at least one non-transitory, tangible memory on which instructions are recorded. The controller is configured to divide the lens into a plurality of regions, and define segmentation lines for the plurality of regions based in part on predetermined reference values. The controller is configured to adjust the segmentation lines to fit respective areas adjacent to the plurality of regions, the respective areas having a relatively high gradient value. A respective mean opacity for the plurality of regions is determined based on the volumetric OCT data. The controller is configured to generate a cataract distribution trace of the lens based on the respective mean opacity in the plurality of regions.
A61B 3/117 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A surgical instrument includes a tube and a horn. The tube has a distal end and a proximal end. A loop is formed with a cable that is folded between a first end of the cable and a second end of the cable. The cable is at least partially disposed in the tube. The horn is configured to oscillate. The first end of the cable is coupled to the horn. An oscillation of the horn actuates the cable.
A system includes an aberrometer configured to measure an eye of a patient, a computing device, and possibly one or more other imaging modalities. The computing device is configured to receive frames from the aberrometer and calculate noise data from at least one of (a) the frames and (b) images of the eye obtained using an imaging modality. The computing device processes the noise data, such as using a machine learning model, to obtain labels for the frames and selects a selected frame from the frames according to the labels. The computing device processes the selected frame to obtain a refractive error of the eye.
A61B 3/103 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining refraction, e.g. refractometers, skiascopes
92.
SURGICAL PACKAGES FOR OPHTHALMIC SURGERY SETUP ROBOT
In certain embodiments, a surgical package is described that facilitates opening by an end effector of a robotic system. The surgical package includes a body defining an interior volume configured to store one or more surgical items therein. A first portion of the body defines a first opening into the interior volume. The surgical package further includes a cover defining a sealing surface configured to contact the first portion to cover the first opening and isolate the interior volume from ambient, and a projecting interface that extends beyond an areal extent of the first portion. The projecting interface is configured to be manipulated by the end effector to overcome a sealing force between the cover and the first portion.
In some embodiments, a system for dispensing a fluid includes a dispensing plug and a squeezable container for receiving the dispensing plug and storing the fluid. The dispensing plug includes a one-way valve for dispensing the fluid. The squeezable container includes a squeezable wall, an opening for dispensing the fluid that is sealed airtight by the dispensing plug, an air-return hole in the squeezable wall, and an air-return valve that is permeable to air and impermeable to the fluid and that closes the air-return hole. The fluid leaves the squeezable container through the one-way valve of the dispensing plug in response to exerting a pressure onto the squeezable wall, and air enters the squeezable container through the air-return valve upon expansion of the squeezable wall in response to releasing the pressure onto the squeezable wall.
A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
B05B 11/04 - Deformable containers producing the flow, e.g. squeeze bottles
B65D 1/32 - Containers adapted to be temporarily deformed by external pressure to expel contents
B65D 47/18 - Closures with discharging devices other than pumps with pouring spouts or tubesClosures with discharging devices other than pumps with discharge nozzles or passages for discharging dropsDroppers
B65D 51/16 - Closures not otherwise provided for with means for venting air or gas
B65D 35/00 - Pliable tubular containers adapted to be permanently deformed to expel contents, e.g. collapsible tubes for toothpaste or other plastic or semi-liquid materialHolders therefor
B65D 35/28 - Pliable tubular containers adapted to be permanently deformed to expel contents, e.g. collapsible tubes for toothpaste or other plastic or semi-liquid materialHolders therefor with auxiliary devices for expelling contents
An apparatus for eye surgery may include an implant support, a folding arm (330), an edge roller (335), and a dial (320). Some embodiments of the implant support may include an implant bay, a tab rail, a tab slot, and a pawl. The folding arm may be coupled to the implant support and may include a dial pin. The edge roller may be coupled to the implant support and may include a roller track. Some embodiments of the dial may include an arm track, a roller pin, a plurality of ratchet teeth, and a tab. The dial can be configured to be rotated relative to the implant support so that the ratchet teeth rotate relative to the pawl, the dial pin travels the arm track and causes the folding arm to rotate, and the roller pin then travels the roller track to cause the edge roller to rotate.
An apparatus for eye surgery may include an implant support (325), a folding arm (330), an edge roller (335), and a dial (320). Some embodiments of the implant support may include an implant bay, a tab rail, a tab slot, and a pawl. The folding arm may be coupled to the implant support and may include a dial pin. The edge roller may be coupled to the implant support and may include a roller track. Some embodiments of the dial may include an arm track, a roller pin, a plurality of ratchet teeth, and a tab. The tab can be configured to be aligned with the tab slot so that arm track engages the dial pin, and the roller pin engages the roller track. The dial can be configured to be rotated to move the tab behind the tab rail and to engage the ratchet teeth with the pawl.
A system includes an ophthalmic microscope configured to capture video of an ophthalmic treatment. A computer system receives the video and a treatment plan for the ophthalmic treatment and processes the video and the treatment plan using a machine learning model to divide the video into a plurality of video segments, each video segment of the plurality of video segments corresponding to a procedure of a plurality of procedures included in the ophthalmic treatment. The computer system may process the video using a machine learning model to label each frame of a plurality of frames of the video with an identifier of a procedure of a plurality of procedures included in the ophthalmic treatment represented in each frame and at least one of (a) select information for display on the display device according to the identifier and (b) control operation of surgical equipment according to the identifier.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
A61B 34/20 - Surgical navigation systemsDevices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
A system includes an aberrometer configured to measure an eye of a patient, a computing device, and possibly one or more other imaging modalities. The computing device is configured to receive frames from the aberrometer and calculate noise data from at least one of (a) the frames and (b) images of the eye obtained using an imaging modality. The computing device processes the noise data, such as using a machine learning model, to obtain labels for the frames and selects a selected frame from the frames according to the labels. The computing device processes the selected frame to obtain a refractive error of the eye.
A61B 3/103 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining refraction, e.g. refractometers, skiascopes
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/107 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining the shape or measuring the curvature of the cornea
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 3/14 - Arrangements specially adapted for eye photography
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
98.
QUANTIFICATION OF DEFICIENT OCULAR IMAGE FEATURES BASED ON MACHINE LEARNING
A system for assessing an eye using an optical coherence tomography (“OCT”) device includes a controller having at least one processor and at least one non-transitory, tangible memory on which instructions are recorded. The controller is adapted to receive an original OCT image of the eye captured via an OCT device. At least one learning module is selectively executable by the controller. The learning module is trained by a training network with a dataset having respective historical ultrasound bio-microscopy images and respective historical OCT images. The controller is adapted to receive input data, including the original OCT image and biometric parameters of the eye. The controller is adapted to execute the at least one learning module to generate one or more quantified image features based on the original OCT input data. The quantified image features include a lens thickness and a lens diameter.
A method includes measuring an eye of a patient according to a plurality of imaging modalities to obtain a plurality of measurements, such as an OCT image, aberrometer measurement, or visible light image. The measurements are processed to obtain a characterization of lens scattering and a characterization of lens accommodation. A dysfunctional lens syndrome score is calculated for the lens according to the characterizations of lens scattering and accommodation and the dysfunctional lens syndrome score is output.
The present disclosure generally relates to a system and method of authenticating a provider prior to performing a procedure. The system includes an optometric or ophthalmic device, an iris imager, and one or more processors. The one or more processors acquire, using the iris imager, an image of an iris of a provider, and attempt to authenticate the provider using a comparison of the image of the iris with a reference iris scan of the provider. Responsive to authenticating the provider, the one or more processors access a set of one or more procedures approved for the provider. Responsive to determining that a procedure is included in the set of one or more procedures, the one or more processors configure operation of the optometric or ophthalmic device to perform the procedure.
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 70/20 - ICT specially adapted for the handling or processing of medical references relating to practices or guidelines