Nalpropion Pharmaceuticals LLC

United States of America

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        Patent 37
        Trademark 25
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        United States 48
        Europe 8
        Canada 6
Date
2025 (YTD) 3
2024 5
2023 1
2022 4
2021 5
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IPC Class
A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine 35
A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine 33
A61P 3/04 - AnorexiantsAntiobesity agents 16
A61K 31/423 - Oxazoles condensed with carbocyclic rings 10
A61K 31/138 - Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine 9
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NICE Class
05 - Pharmaceutical, veterinary and sanitary products 17
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services 16
16 - Paper, cardboard and goods made from these materials 10
35 - Advertising and business services 1
Status
Pending 17
Registered / In Force 45

1.

CONTRAVE CONNEX

      
Serial Number 99199694
Status Pending
Filing Date 2025-05-23
Owner Nalpropion Pharmaceuticals LLC ()
NICE Classes  ? 35 - Advertising and business services

Goods & Services

Prescription fulfillment services, namely, retail on-line order pharmacy services, mail-order pharmacy services, and retail phone order pharmacy services for members; business consulting services with a focus on cost management for the health care benefit plans of others namely, assisting health care benefit providers with identifying areas of cost savings; prior authorization facilitation, also known as healthcare cost containment services, namely, providing expedited review, processing and follow-up of prior authorization requests initiated by physicians' offices and pharmacies

2.

Pharmaceutical formulations comprising naltrexone and/or bupropion

      
Application Number 18917080
Grant Number 12303604
Status In Force
Filing Date 2024-10-16
First Publication Date 2025-05-20
Grant Date 2025-05-20
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Churchill, Rob
  • Chesnut, Aaron

Abstract

Described are pharmaceutical formulations comprising naltrexone and/or bupropion. Such pharmaceutical formulations can comprise extended-release, multilayer beads. Also described are methods of administering such formulations, such as for the treatment of overweight or obesity.

IPC Classes  ?

  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine

3.

Compositions And Methods For Reducing Major Adverse Cardiovascular Events

      
Application Number 18731965
Status Pending
Filing Date 2024-06-03
First Publication Date 2025-05-08
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Klassen, Preston
  • Taylor, Kristin

Abstract

The present application relates to compositions, kits, uses, systems and methods of using naltrexone and bupropion, or pharmaceutically acceptable salts thereof, for reducing the risk of adverse cardiovascular outcomes or events, including Major Adverse Cardiovascular Events (MACE) in subjects, preferably those at increased risk of adverse cardiovascular outcomes of MACE, that may be overweight or obese. The present application also relates to compositions, kits, uses, systems and methods of using naltrexone and bupropion or pharmaceutically acceptable salts thereof for treatment of overweight of obesity in subjects, preferably at increased risk of adverse cardiovascular outcomes or MACE, wherein the treatment reduces the risk of MACE.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • A61P 3/06 - Antihyperlipidemics
  • A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
  • A61P 9/00 - Drugs for disorders of the cardiovascular system
  • A61P 9/02 - Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
  • A61P 9/04 - Inotropic agents, i.e. stimulants of cardiac contractionDrugs for heart failure
  • A61P 9/06 - Antiarrhythmics
  • A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
  • A61P 9/12 - Antihypertensives
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups

4.

ONE SIZE DOES NOT FIT ALL

      
Serial Number 98894603
Status Pending
Filing Date 2024-12-10
Owner Nalpropion Pharmaceuticals LLC ()
NICE Classes  ? 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Providing health information; Providing medical information; Providing medical information in the field of weight loss, weight management, obesity, hunger, and cravings

5.

Methods For Administering Weight Loss Medications

      
Application Number 18770144
Status Pending
Filing Date 2024-07-11
First Publication Date 2024-11-07
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Mckinney, Anthony A.
  • Tollefson, Gary D.
  • Weber, Eckard
  • Soltero, Richard

Abstract

Methods and systems for administration of pharmaceuticals using a unit dosage package that includes a first unit dosage that has a first drug and a second drug, a second unit dosage that has the first drug and the second drug, where the second unit dosage includes a different amount of the second drug than the first unit dosage and a unit dosage package is configured to hold the first unit dosage and the second unit dosage. In preferred embodiments the methods and systems are used for administration of weight loss medications.

IPC Classes  ?

  • A61K 9/24 - Layered or laminated unitary dosage forms
  • A61J 1/03 - Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
  • A61J 7/04 - Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
  • A61K 31/135 - Amines, e.g. amantadine having aromatic rings, e.g. methadone
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/138 - Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
  • A61K 31/35 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
  • A61K 31/42 - Oxazoles
  • A61K 31/423 - Oxazoles condensed with carbocyclic rings
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/551 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
  • A61K 31/5513 - 1,4-Benzodiazepines, e.g. diazepam
  • A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • B65D 75/36 - Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages

6.

FOOD NOISE

      
Serial Number 98371260
Status Pending
Filing Date 2024-01-23
Owner Nalpropion Pharmaceuticals LLC ()
NICE Classes  ? 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Providing health information; Providing medical information

7.

QUIET FOOD NOISE

      
Serial Number 98371282
Status Pending
Filing Date 2024-01-23
Owner Nalpropion Pharmaceuticals LLC ()
NICE Classes  ? 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Providing health information; Providing medical information

8.

STOP FOOD NOISE

      
Serial Number 98371299
Status Pending
Filing Date 2024-01-23
Owner Nalpropion Pharmaceuticals LLC ()
NICE Classes  ? 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Providing health information; Providing medical information

9.

Layered Pharmaceutical Formulations

      
Application Number 18143254
Status Pending
Filing Date 2023-05-04
First Publication Date 2023-09-28
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Mckinney, Anthony A.
  • Tollefson, Gary D.
  • Weber, Eckard
  • Soltero, Richard

Abstract

In one embodiment a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers, the intermediate layer configured to dissolve in vivo to thereby leave the two or more pharmaceutical layers substantially intact. In one embodiment, an active pharmaceutical ingredient in at least one of the pharmaceutical layers is selected from bupropion, zonisamide, naltrexone, topiramate, phentermine, metformin, olanzapine and fluoxetine.

IPC Classes  ?

  • A61K 9/24 - Layered or laminated unitary dosage forms
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/138 - Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
  • A61K 31/155 - Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (HN=C(OH)NH2), isothiourea (HN=C(SH)—NH2)
  • A61K 31/35 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
  • A61K 31/423 - Oxazoles condensed with carbocyclic rings
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/5513 - 1,4-Benzodiazepines, e.g. diazepam
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/42 - Oxazoles
  • A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 31/357 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
  • A61K 31/551 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep

10.

EMOTIONAL EATING

      
Serial Number 97699491
Status Pending
Filing Date 2022-12-01
Owner Nalpropion Pharmaceuticals LLC ()
NICE Classes  ? 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Providing medical information in the field of weight loss, weight management, obesity, hunger, and cravings

11.

Increasing Drug Bioavailability In Naltrexone Therapy

      
Application Number 17717691
Status Pending
Filing Date 2022-04-11
First Publication Date 2022-07-28
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Flanagan, Shawn
  • Dunayevich, Eduardo

Abstract

Disclosed are compositions, uses, methods and kits for increasing drug bioavailability in a naltrexone therapy.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine

12.

Methods Of Treating Overweight And Obesity

      
Application Number 17493160
Status Pending
Filing Date 2021-10-04
First Publication Date 2022-06-30
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Klassen, Preston
  • Taylor, Kristin

Abstract

The present disclosure relates to compositions, kits, uses, systems and methods for treating overweight and obesity using naltrexone plus bupropion, preferably in combination with a comprehensive web-based and/or telephone-based weight management program, and preferably in subjects at increased risk of adverse cardiovascular outcomes.

IPC Classes  ?

  • G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • G01G 19/414 - Weighing apparatus or methods adapted for special purposes not provided for in groups with provisions for indicating, recording, or computing price or other quantities dependent on the weight using electromechanical or electronic computing means using electronic computing means only
  • A61P 9/04 - Inotropic agents, i.e. stimulants of cardiac contractionDrugs for heart failure
  • A61P 9/00 - Drugs for disorders of the cardiovascular system
  • A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • G09B 5/06 - Electrically-operated educational appliances with both visual and audible presentation of the material to be studied
  • G09B 19/00 - Teaching not covered by other main groups of this subclass

13.

Increasing Drug Bioavailability In Naltrexone Therapy

      
Application Number 17343326
Status Pending
Filing Date 2021-06-09
First Publication Date 2022-03-24
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Flanagan, Shawn
  • Dunayevich, Eduardo

Abstract

Disclosed are compositions, uses, methods and kits for increasing drug bioavailability in a naltrexone therapy.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine

14.

Compositions and Methods for Increasing Insulin Sensitivity

      
Application Number 17335646
Status Pending
Filing Date 2021-06-01
First Publication Date 2021-11-11
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Cowley, Michael Alexander
  • Mckinney, Anthony A.
  • Tollefson, Gary D.

Abstract

Methods and compositions for treating a blood glucose condition involve identifying a suitable subject and administering an effective amount of a composition that contains one or more of an opioid antagonist, an anticonvulsant, and a psychotherapeutic agent. The compositions can include insulin. In some embodiments, such methods and compositions can be used to modulate a blood glucose level. In preferred embodiments, such methods and compositions are useful for increasing a subject's sensitivity to insulin.

IPC Classes  ?

  • A61K 38/28 - Insulins
  • A61K 31/135 - Amines, e.g. amantadine having aromatic rings, e.g. methadone
  • A61K 31/138 - Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
  • A61K 31/423 - Oxazoles condensed with carbocyclic rings
  • A61K 31/445 - Non-condensed piperidines, e.g. piperocaine
  • A61K 31/4525 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
  • A61K 31/5415 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
  • A61K 31/551 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
  • A61K 31/554 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and at least one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
  • A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
  • A61K 31/5513 - 1,4-Benzodiazepines, e.g. diazepam
  • A61K 31/35 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/357 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel

15.

Methods Of Providing Weight Loss Therapy In Patients With Major Depression

      
Application Number 17346902
Status Pending
Filing Date 2021-06-14
First Publication Date 2021-09-30
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Dunayevich, Eduardo
  • Tollefson, Gary D.

Abstract

Disclosed are methods of providing weight loss therapy, particularly for patients suffering from major depression.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • A61K 31/439 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine

16.

Methods For Reducing Binge Or Compulsive Eating

      
Application Number 17336546
Status Pending
Filing Date 2021-06-02
First Publication Date 2021-09-16
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Dunayevich, Eduardo
  • Mcelroy, Susan
  • Landbloom, Ron

Abstract

Compositions, uses, kits and methods for reducing hinge or compulsive eating are described herein. Methods may include administering an effective combination of a dosage of a bupropion or a pharmaceutically acceptable salt thereof, and a dosage of naltrexone or a pharmaceutically acceptable salt thereof. Methods may include identifying a patient who is overweight or obese and providing an effective combination of bupropion and naltrexone to the patient. Methods may include reducing a number of binge or compulsive eating events. Methods may include reducing severity of binge or compulsive eating events.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 9/00 - Medicinal preparations characterised by special physical form

17.

Compositions And Methods For Reducing Food Cravings

      
Application Number 17319882
Status Pending
Filing Date 2021-05-13
First Publication Date 2021-09-02
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Mckinney, Anthony A.
  • Tollefson, Gary D.
  • Cowley, Michael Alexander

Abstract

Disclosed are compositions for reducing food cravings, comprising a first compound and a second compound, where the first compound is an opioid antagonist and the second compound is an α-MSH agonist. Also disclosed are methods of reducing food cravings, comprising identifying an individual in need thereof and treating that individual to antagonize opioid receptor activity and to enhance α-MSH activity.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/136 - Amines, e.g. amantadine having aromatic rings, e.g. methadone having the amino group directly attached to the aromatic ring, e.g. benzeneamine
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/138 - Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
  • A61K 31/15 - Oximes (C=N—O—)Hydrazines (N—N)Hydrazones (N—N=)
  • A61K 31/19 - Carboxylic acids, e.g. valproic acid
  • A61K 31/197 - Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
  • A61K 31/343 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
  • A61K 31/351 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
  • A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
  • A61K 31/4166 - 1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
  • A61K 31/423 - Oxazoles condensed with carbocyclic rings
  • A61K 31/451 - Non-condensed piperidines, e.g. piperocaine having a carbocyclic ring directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
  • A61K 31/4525 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
  • A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
  • A61K 31/5513 - 1,4-Benzodiazepines, e.g. diazepam
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

18.

Compositions and methods for reducing major adverse cardiovascular events

      
Application Number 17099316
Grant Number 11998542
Status In Force
Filing Date 2020-11-16
First Publication Date 2021-03-11
Grant Date 2024-06-04
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Klassen, Preston
  • Taylor, Kristin

Abstract

The present application relates to compositions, kits, uses, systems and methods of using naltrexone and bupropion, or pharmaceutically acceptable salts thereof, for reducing the risk of adverse cardiovascular outcomes or events, including Major Adverse Cardiovascular Events (MACE) in subjects, preferably those at increased risk of adverse cardiovascular outcomes or MACE, that may be overweight or obese. The present application also relates to compositions, kits, uses, systems and methods of using naltrexone and bupropion or pharmaceutically acceptable alts thereof for treatment of overweight or obesity in subjects, preferably at increased risk of adverse cardiovasular outcomes or MACE, wherein the treatment reduce, the risk of MACE.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • A61P 3/06 - Antihyperlipidemics
  • A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
  • A61P 9/00 - Drugs for disorders of the cardiovascular system
  • A61P 9/02 - Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
  • A61P 9/04 - Inotropic agents, i.e. stimulants of cardiac contractionDrugs for heart failure
  • A61P 9/06 - Antiarrhythmics
  • A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
  • A61P 9/12 - Antihypertensives
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups

19.

Methods for administering weight loss medications

      
Application Number 16938443
Grant Number 12048769
Status In Force
Filing Date 2020-07-24
First Publication Date 2020-11-12
Grant Date 2024-07-30
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Mckinney, Anthony A
  • Tollefson, Gary D.
  • Weber, Eckard
  • Soltero, Richard

Abstract

Methods and systems for administration of pharmaceuticals using a unit dosage package that includes a first unit dosage that has a first drug and a second drug, a second unit dosage that has the first drug and the second drug, where the second unit dosage includes a different amount of the second drug than the first unit dosage and a unit dosage package is configured to hold the first unit dosage and the second unit dosage. In preferred embodiments the methods and systems are used for administration of weight loss medications.

IPC Classes  ?

  • A61K 9/24 - Layered or laminated unitary dosage forms
  • A61J 1/03 - Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
  • A61J 7/04 - Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
  • A61K 31/135 - Amines, e.g. amantadine having aromatic rings, e.g. methadone
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/138 - Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
  • A61K 31/35 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
  • A61K 31/42 - Oxazoles
  • A61K 31/423 - Oxazoles condensed with carbocyclic rings
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/551 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
  • A61K 31/5513 - 1,4-Benzodiazepines, e.g. diazepam
  • A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • B65D 75/36 - Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages

20.

Methods of treating overweight and obesity

      
Application Number 16558211
Grant Number 11139056
Status In Force
Filing Date 2019-09-02
First Publication Date 2020-03-26
Grant Date 2021-10-05
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Klassen, Preston
  • Taylor, Kristin

Abstract

The present disclosure relates to compositions, kits, uses, systems and methods for treating overweight and obesity using naltrexone plus bupropion, preferably in combination with a comprehensive web-based and/or telephone-based weight management program, and preferably in subjects at increased risk of adverse cardiovascular outcomes.

IPC Classes  ?

  • G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • G01G 19/414 - Weighing apparatus or methods adapted for special purposes not provided for in groups with provisions for indicating, recording, or computing price or other quantities dependent on the weight using electromechanical or electronic computing means using electronic computing means only
  • A61P 9/04 - Inotropic agents, i.e. stimulants of cardiac contractionDrugs for heart failure
  • A61P 9/00 - Drugs for disorders of the cardiovascular system
  • A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • G09B 5/06 - Electrically-operated educational appliances with both visual and audible presentation of the material to be studied
  • G09B 19/00 - Teaching not covered by other main groups of this subclass

21.

Compositions and methods for weight loss in at risk patient populations

      
Application Number 16356657
Grant Number 10828294
Status In Force
Filing Date 2019-03-18
First Publication Date 2019-12-12
Grant Date 2020-11-10
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Klassen, Preston
  • Taylor, Kristin

Abstract

The present disclosure relates to compositions, kits, uses, systems and methods related to naltrexone plus bupropion for treating an overweight or obese subject at increased risk of adverse cardiovascular outcomes. Preferably, the subject has had type-two diabetes for a period of less than 6 years or is a current smoker, optionally that does not have type-two diabetes.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine

22.

Compositions and methods for reducing major adverse cardiovascular events

      
Application Number 16356663
Grant Number 10835527
Status In Force
Filing Date 2019-03-18
First Publication Date 2019-10-17
Grant Date 2020-11-17
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Klassen, Preston
  • Taylor, Kristin

Abstract

The present application relates to compositions, kits, uses, systems and methods of using naltrexone and bupropion, or pharmaceutically acceptable salts thereof, for reducing the risk of adverse cardiovascular outcomes or events, including Major Adverse Cardiovascular Events (MACE) in subjects, preferably those at increased risk of adverse cardiovascular outcomes or MACE, that may be overweight or obese. The present application also relates to compositions, kits, uses, systems and methods of using naltrexone and bupropion or pharmaceutically acceptable salts thereof for treatment of overweight or obesity in subjects, preferably at increased risk of adverse cardiovascular outcomes or MACE, wherein the treatment reduces the risk of MACE.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine

23.

Methods of providing weight loss therapy in patients with major depression

      
Application Number 16441863
Grant Number 11033543
Status In Force
Filing Date 2019-06-14
First Publication Date 2019-09-26
Grant Date 2021-06-15
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor
  • Dunayevich, Eduardo
  • Tollefson, Gary

Abstract

Disclosed are methods of providing weight loss therapy, particularly for patients suffering from major depression.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/439 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
  • A61K 9/00 - Medicinal preparations characterised by special physical form

24.

Sustained Release Formulation Of Naltrexone

      
Application Number 16284453
Status Pending
Filing Date 2019-02-25
First Publication Date 2019-06-20
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Mckinney, Anthony A.
  • Tollefson, Gary
  • Soltero, Richard
  • Dunzo, Thea Elise

Abstract

A sustained-release oral dosage form of naltrexone or a pharmaceutically acceptable salt thereof is provided. The oral dosage form may be administered with another compound. Administration of the oral dosage form may reduce a side effect, which may be a side effect at least partially attributable to a weight-loss treatment. The oral dosage form may be administered to treat a weight-loss condition.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/24 - Layered or laminated unitary dosage forms
  • A61K 31/12 - Ketones

25.

Methods for administering weight loss medications

      
Application Number 16101853
Grant Number 10307376
Status In Force
Filing Date 2018-08-13
First Publication Date 2018-12-20
Grant Date 2019-06-04
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Mckinney, Anthony A.
  • Tollefson, Gary
  • Weber, Eckard
  • Soltero, Rick

Abstract

Methods and systems for administration of pharmaceuticals using a unit dosage package that includes a first unit dosage that has a first drug and a second drug, a second unit dosage that has the first drug and the second drug, where the second unit dosage includes a different amount of the second drug than the first unit dosage and a unit dosage package is configured to hold the first unit dosage and the second unit dosage. In preferred embodiments the methods and systems are used for administration of weight loss medications.

IPC Classes  ?

  • A61J 1/03 - Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
  • A61J 7/04 - Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
  • A61K 9/24 - Layered or laminated unitary dosage forms
  • A61K 31/35 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
  • A61K 31/42 - Oxazoles
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • B65D 75/36 - Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages
  • A61K 31/135 - Amines, e.g. amantadine having aromatic rings, e.g. methadone
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/138 - Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
  • A61K 31/423 - Oxazoles condensed with carbocyclic rings
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/551 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
  • A61K 31/5513 - 1,4-Benzodiazepines, e.g. diazepam
  • A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin

26.

Compositions and methods for weight loss in at risk patient populations

      
Application Number 15725830
Grant Number 10231964
Status In Force
Filing Date 2017-10-05
First Publication Date 2018-08-30
Grant Date 2019-03-19
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Klassen, Preston
  • Taylor, Kristin

Abstract

The present disclosure relates to compositions, kits, uses, systems and methods related to naltrexone plus bupropion for treating an overweight or obese subject at increased risk of adverse cardiovascular outcomes. Preferably, the subject has had type-two diabetes for a period of less than 6 years or is a current smoker, optionally that does not have type-two diabetes.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine

27.

Methods of treating overweight and obesity

      
Application Number 15491870
Grant Number 10403170
Status In Force
Filing Date 2017-04-19
First Publication Date 2017-08-03
Grant Date 2019-09-03
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Klassen, Preston
  • Taylor, Kristin

Abstract

The present disclosure relates to compositions, kits, uses, systems and methods for treating overweight and obesity using naltrexone plus bupropion, preferably in combination with a comprehensive web-based and/or telephone-based weight management program, and preferably in subjects at increased risk of adverse cardiovascular outcomes.

IPC Classes  ?

  • G09B 5/06 - Electrically-operated educational appliances with both visual and audible presentation of the material to be studied
  • G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
  • G09B 19/00 - Teaching not covered by other main groups of this subclass
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • G01G 19/414 - Weighing apparatus or methods adapted for special purposes not provided for in groups with provisions for indicating, recording, or computing price or other quantities dependent on the weight using electromechanical or electronic computing means using electronic computing means only

28.

Methods for treating visceral fat conditions

      
Application Number 15446933
Grant Number 11324741
Status In Force
Filing Date 2017-03-01
First Publication Date 2017-06-22
Grant Date 2022-05-10
Owner Nalpropion Pharmaceuticals LLC (USA)
Inventor Tollefson, Gary D.

Abstract

Disclosed are methods and compositions for treating visceral fat conditions and/or metabolic syndrome using combinations of naltrexone and bupropion.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine

29.

GET CONTRAVE NOW

      
Serial Number 87301815
Status Registered
Filing Date 2017-01-13
Registration Date 2018-10-16
Owner NALPROPION PHARMACEUTICALS LLC ()
NICE Classes  ? 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Online pharmaceutical advice, namely, providing online consultation and information for the ordering of pharmaceuticals; Providing information in the field of weight management and the treatment of obesity

30.

Compositions and methods for reducing major adverse cardiovascular events

      
Application Number 15101878
Grant Number 10231962
Status In Force
Filing Date 2014-12-04
First Publication Date 2016-10-27
Grant Date 2019-03-19
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Klassen, Preston
  • Taylor, Kristin

Abstract

The present application relates to compositions, kits, uses, systems and methods of using naltrexone and bupropion, or pharmaceutically acceptable salts thereof, for reducing the risk of adverse cardiovascular outcomes or events, including Major Adverse Cardiovascular Events (MACE) in subjects, preferably those at increased risk of adverse cardiovascular outcomes or MACE, that may be overweight or obese. The present application also relates to compositions, kits, uses, systems and methods of using naltrexone and bupropion or pharmaceutically acceptable salts thereof for treatment of overweight or obesity in subjects, preferably at increased risk of adverse cardiovascular outcomes or MACE, wherein the treatment reduces the risk of MACE.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine

31.

MYSIMBA

      
Application Number 179681500
Status Registered
Filing Date 2016-08-16
Registration Date 2019-07-10
Owner Nalpropion Pharmaceuticals LLC (USA)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 16 - Paper, cardboard and goods made from these materials
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

(1) Pharmaceutical preparations for use in the treatment of obesity and inducing weight loss. (2) Printed materials, namely, brochures, newsletters and bulletins on the topic of weight management and treatment of obesity. (1) Providing medical information in the field of weight management and the treatment of obesity.

32.

Methods of providing weight loss therapy in patients with major depression

      
Application Number 15011120
Grant Number 10322121
Status In Force
Filing Date 2016-01-29
First Publication Date 2016-05-26
Grant Date 2019-06-18
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Dunayevich, Eduardo
  • Tollefson, Gary D.

Abstract

Disclosed are methods of providing weight loss therapy, particularly for patients suffering from major depression.

IPC Classes  ?

  • A61K 31/439 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 9/00 - Medicinal preparations characterised by special physical form

33.

Compositions and methods for weight loss in at risk patient populations

      
Application Number 14839792
Grant Number 09801875
Status In Force
Filing Date 2015-08-28
First Publication Date 2015-12-24
Grant Date 2017-10-31
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Klassen, Preston
  • Taylor, Kristin

Abstract

The present disclosure relates to compositions, kits, uses, systems and methods related to naltrexone plus bupropion for treating an overweight or obese subject at increased risk of adverse cardiovascular outcomes. Preferably, the subject has had type-two diabetes for a period of less than 6 years or is a current smoker, optionally that does not have type-two diabetes.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine

34.

Compositions and methods for weight loss in at risk patient populations

      
Application Number 14635518
Grant Number 09119850
Status In Force
Filing Date 2015-03-02
First Publication Date 2015-07-02
Grant Date 2015-09-01
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Klassen, Preston
  • Taylor, Kristin

Abstract

The present disclosure relates to compositions, kits, uses, systems and methods related to naltrexone plus bupropion for treating an overweight or obese subject at increased risk of adverse cardiovascular outcomes. Preferably, the subject has had type-two diabetes for a period of less than 6 years or is a current smoker, optionally that does not have type-two diabetes.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine

35.

Methods of treating overweight and obesity

      
Application Number 14405775
Grant Number 09633575
Status In Force
Filing Date 2013-06-05
First Publication Date 2015-06-04
Grant Date 2017-04-25
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Klassen, Preston
  • Taylor, Kristin

Abstract

The present disclosure relates to compositions, kits, uses, systems and methods for treating overweight and obesity using naltrexone plus bupropion, preferably in combination with a comprehensive web-based and/or telephone-based weight management program, and preferably in subjects at increased risk of adverse cardiovascular outcomes.

IPC Classes  ?

  • A61K 31/44 - Non-condensed pyridinesHydrogenated derivatives thereof
  • G09B 19/00 - Teaching not covered by other main groups of this subclass
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • G09B 5/06 - Electrically-operated educational appliances with both visual and audible presentation of the material to be studied
  • G01G 19/414 - Weighing apparatus or methods adapted for special purposes not provided for in groups with provisions for indicating, recording, or computing price or other quantities dependent on the weight using electromechanical or electronic computing means using electronic computing means only

36.

Sustained release formulation of naltrexone

      
Application Number 14555475
Grant Number 09107837
Status In Force
Filing Date 2014-11-26
First Publication Date 2015-03-19
Grant Date 2015-08-18
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Mckinney, Anthony A.
  • Tollefson, Gary D.
  • Soltero, Richard
  • Dunzo, Thea Elise

Abstract

A sustained-release oral dosage form of naltrexone or a pharmaceutically acceptable salt thereof is provided. The oral dosage form may be administered with another compound. Administration of the oral dosage form may reduce a side effect, which may be a side effect at least partially attributable to a weight-loss treatment. The oral dosage form may be administered to treat a weight-loss condition.

IPC Classes  ?

37.

Compositions and methods for weight loss in at risk patient populations

      
Application Number 14322810
Grant Number 08969371
Status In Force
Filing Date 2014-07-02
First Publication Date 2015-03-03
Grant Date 2015-03-03
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Klassen, Preston
  • Taylor, Kristin

Abstract

The present disclosure relates to compositions, kits, uses, systems and methods related to naltrexone plus bupropion for treating an overweight or obese subject at increased risk of adverse cardiovascular outcomes. Preferably, the subject has had type-two diabetes for a period of less than 6 years or is a current smoker, optionally that does not have type-two diabetes.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine

38.

Methods for administering weight loss medications

      
Application Number 14220349
Grant Number 09125868
Status In Force
Filing Date 2014-03-20
First Publication Date 2014-10-30
Grant Date 2015-09-08
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Mckinney, Anthony A.
  • Tollefson, Gary
  • Weber, Eckard
  • Soltero, Rick

Abstract

Methods and systems for administration of pharmaceuticals using a unit dosage package that includes a first unit dosage that has a first drug and a second drug, a second unit dosage that has the first drug and the second drug, where the second unit dosage includes a different amount of the second drug than the first unit dosage and a unit dosage package is configured to hold the first unit dosage and the second unit dosage. In preferred embodiments the methods and systems are used for administration of weight loss medications.

IPC Classes  ?

  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 31/415 - 1,2-Diazoles
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/439 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
  • A61K 31/35 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
  • A61K 31/551 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
  • A61P 3/04 - AnorexiantsAntiobesity agents
  • A61K 31/138 - Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
  • A61J 1/03 - Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
  • A61J 7/04 - Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
  • A61K 31/135 - Amines, e.g. amantadine having aromatic rings, e.g. methadone
  • A61K 31/42 - Oxazoles
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61K 31/423 - Oxazoles condensed with carbocyclic rings
  • A61K 9/24 - Layered or laminated unitary dosage forms

39.

Compositions and methods for increasing insulin sensitivity

      
Application Number 14326075
Grant Number 09457005
Status In Force
Filing Date 2014-07-08
First Publication Date 2014-10-30
Grant Date 2016-10-04
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Cowley, Michael A.
  • Mckinney, Anthony A.
  • Tollefson, Gary

Abstract

Methods and compositions for treating a blood glucose condition involve identifying a suitable subject and administering an effective amount of a composition that contains one or more of an opioid antagonist, an anticonvulsant, and a psychotherapeutic agent. The compositions can include insulin. In some embodiments, such methods and compositions can be used to modulate a blood glucose level. In preferred embodiments, such methods and compositions are useful for increasing a subject's sensitivity to insulin.

IPC Classes  ?

  • A61K 38/28 - Insulins
  • A61K 31/135 - Amines, e.g. amantadine having aromatic rings, e.g. methadone
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/5513 - 1,4-Benzodiazepines, e.g. diazepam
  • A61K 31/35 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
  • A61K 31/4525 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
  • A61K 31/423 - Oxazoles condensed with carbocyclic rings
  • A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
  • A61K 31/138 - Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
  • A61K 31/445 - Non-condensed piperidines, e.g. piperocaine
  • A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
  • A61K 31/5415 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
  • A61K 31/551 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
  • A61K 31/554 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and at least one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
  • A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

40.

MYSIMBA

      
Application Number 013395199
Status Registered
Filing Date 2014-10-23
Registration Date 2015-03-16
Owner NALPROPION PHARMACEUTICALS LLC (USA)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 16 - Paper, cardboard and goods made from these materials
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical preparations for use in the treatment of obesity and inducing weight loss. Printed materials, namely, brochures, newsletters and bulletins on the topic of weight management and treatment of obesity. Providing medical information in the field of weight management and the treatment of obesity.

41.

YISINGA

      
Application Number 013000989
Status Registered
Filing Date 2014-06-16
Registration Date 2014-11-07
Owner NALPROPION PHARMACEUTICALS LLC (USA)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 16 - Paper, cardboard and goods made from these materials
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical preparations, including preparations for use in the treatment of obesity and inducing weight loss. Printed materials, including, brochures, newsletters and bulletins on the topic of weight management and treatment of obesity. Providing medical information, including information in the field of weight management and the treatment of obesity.

42.

CONTRAVE

      
Serial Number 86026234
Status Registered
Filing Date 2013-08-01
Registration Date 2017-04-11
Owner NALPROPION PHARMACEUTICALS LLC ()
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 16 - Paper, cardboard and goods made from these materials
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical preparations for use in the treatment of obesity and inducing weight loss Printed materials, namely, brochures, newsletters and bulletins on the topic of weight management and treatment of obesity Medical information services, including the services of providing health information in the field of weight management and the treatment of obesity

43.

Layered pharmaceutical formulations

      
Application Number 13330395
Grant Number 08318788
Status In Force
Filing Date 2011-12-19
First Publication Date 2012-04-19
Grant Date 2012-11-27
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Mckinney, Anthony
  • Tollefson, Gary
  • Weber, Eckard
  • Soltero, Rick

Abstract

In one embodiment a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers, the intermediate layer configured to dissolve in vivo to thereby leave the two or more pharmaceutical layers substantially intact. In one embodiment, an active pharmaceutical ingredient in at least one of the pharmaceutical layers is selected from bupropion, zonisamide, naltrexone, topiramate, phentermine, metformin, olanzapine and fluoxetine.

IPC Classes  ?

  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/423 - Oxazoles condensed with carbocyclic rings
  • A61P 3/04 - AnorexiantsAntiobesity agents

44.

Methods of providing weight loss therapy in patients with major depression

      
Application Number 12987909
Grant Number 09248123
Status In Force
Filing Date 2011-01-10
First Publication Date 2011-07-14
Grant Date 2016-02-02
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Dunayevich, Eduardo
  • Tollefson, Gary

Abstract

Disclosed are methods of providing weight loss therapy, particularly for patients suffering from major depression.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/439 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine

45.

Methods for administering weight loss medications

      
Application Number 12838364
Grant Number 08722085
Status In Force
Filing Date 2010-07-16
First Publication Date 2011-03-10
Grant Date 2014-05-13
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Mckinney, Anthony
  • Tollefson, Gary
  • Weber, Eckard
  • Soltero, Rick

Abstract

Methods and systems for administration of pharmaceuticals using a unit dosage package that includes a first unit dosage that has a first drug and a second drug, a second unit dosage that has the first drug and the second drug, where the second unit dosage includes a different amount of the second drug than the first unit dosage and a unit dosage package is configured to hold the first unit dosage and the second unit dosage. In preferred embodiments the methods and systems are used for administration of weight loss medications.

IPC Classes  ?

  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 31/415 - 1,2-Diazoles
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/439 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
  • A61K 31/35 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
  • A61K 31/551 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
  • A61P 3/04 - AnorexiantsAntiobesity agents

46.

Contrave

      
Application Number 009238247
Status Registered
Filing Date 2010-07-12
Registration Date 2010-12-24
Owner NALPROPION PHARMACEUTICALS LLC (USA)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 16 - Paper, cardboard and goods made from these materials
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical preparations for use in the treatment of obesity and inducing weight loss. Printed materials, namely, brochures, newsletters and bulletins on the topic of weight management and treatment of obesity. Providing medical information in the field of weight management and the treatment of obesity.

47.

CONTRAVE

      
Application Number 148855800
Status Registered
Filing Date 2010-07-07
Registration Date 2018-12-21
Owner Nalpropion Pharmaceuticals LLC (USA)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 16 - Paper, cardboard and goods made from these materials
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

(1) Pharmaceutical preparations for use in the treatment of obesity and inducing weight loss. (2) Printed materials, namely, brochures, newsletters and bulletins on the topic of weight management and treatment of obesity. (1) Providing medical information in the field of weight management and the treatment of obesity.

48.

CONTRAVE

      
Application Number 145499800
Status Registered
Filing Date 2009-10-05
Registration Date 2018-12-21
Owner Nalpropion Pharmaceuticals LLC (USA)
NICE Classes  ?
  • 16 - Paper, cardboard and goods made from these materials
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

(1) Printed materials, namely, brochures, newsletters and bulletins on the topic of weight management and treatment of obesity. (1) Medical information services, namely, providing health information in the field of weight management and the treatment of obesity.

49.

Layered pharmaceutical formulations

      
Application Number 11937421
Grant Number 08088786
Status In Force
Filing Date 2007-11-08
First Publication Date 2008-05-15
Grant Date 2012-01-03
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Mckinney, Anthony
  • Tollefson, Gary
  • Weber, Eckard
  • Soltero, Rick

Abstract

In one embodiment a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers, the intermediate layer configured to dissolve in vivo to thereby leave the two or more pharmaceutical layers substantially intact. In one embodiment, an active pharmaceutical ingredient in at least one of the pharmaceutical layers is selected from bupropion, zonisamide, naltrexone, topiramate, phentermine, metformin, olanzapine and fluoxetine.

IPC Classes  ?

  • A01N 43/42 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings condensed with carbocyclic rings
  • A61K 31/44 - Non-condensed pyridinesHydrogenated derivatives thereof

50.

Sustained release formulation of naltrexone

      
Application Number 11757773
Grant Number 08916195
Status In Force
Filing Date 2007-06-04
First Publication Date 2007-12-06
Grant Date 2014-12-23
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Mckinney, Anthony A.
  • Tollefson, Gary D.
  • Soltero, Richard
  • Dunzo, Thea Elise

Abstract

A sustained-release oral dosage form of naltrexone or a pharmaceutically acceptable salt thereof is provided. The oral dosage form may be administered with another compound. Administration of the oral dosage form may reduce a side effect, which may be a side effect at least partially attributable to a weight-loss treatment. The oral dosage form may be administered to treat a weight-loss condition.

IPC Classes  ?

  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 9/22 - Sustained or differential release type
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 9/20 - Pills, lozenges or tablets

51.

Compositions and methods for increasing insulin sensitivity

      
Application Number 11602571
Grant Number 08815889
Status In Force
Filing Date 2006-11-21
First Publication Date 2007-06-07
Grant Date 2014-08-26
Owner NALPROPION PHARMACEUTICALS LLC (USA)
Inventor
  • Cowley, Michael A.
  • Mckinney, Anthony A.
  • Tollefson, Gary

Abstract

Methods and compositions for treating a blood glucose condition involve identifying a suitable subject and administering an effective amount of a composition that contains one or more of an opioid antagonist, an anticonvulsant, and a psychotherapeutic agent. The compositions can include insulin. In some embodiments, such methods and compositions can be used to modulate a blood glucose level. In preferred embodiments, such methods and compositions are useful for increasing a subject's sensitivity to insulin.

IPC Classes  ?

  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
  • A61K 31/138 - Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
  • A61K 31/4525 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
  • A61K 31/135 - Amines, e.g. amantadine having aromatic rings, e.g. methadone
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61K 31/423 - Oxazoles condensed with carbocyclic rings
  • A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
  • A61K 31/554 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and at least one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
  • A61K 31/5513 - 1,4-Benzodiazepines, e.g. diazepam
  • A61K 31/551 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
  • A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
  • A61K 31/445 - Non-condensed piperidines, e.g. piperocaine
  • A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
  • A61K 31/5415 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam

52.

EMPATIC

      
Application Number 005843073
Status Registered
Filing Date 2007-04-04
Registration Date 2008-03-04
Owner NALPROPION PHARMACEUTICALS LLC (USA)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 16 - Paper, cardboard and goods made from these materials
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical preparations for use in the treatment of obesity and inducing weight loss. Printed materials, including brochures, newsletters and bulletins on the topic of weight management and treatment of obesity. Medical information services, including providing health information in the field of weight management and the treatment of obesity.

53.

OREXIGEN

      
Serial Number 78960760
Status Registered
Filing Date 2006-08-25
Registration Date 2008-03-11
Owner NALPROPION PHARMACEUTICALS LLC ()
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 16 - Paper, cardboard and goods made from these materials
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

PHARMACEUTICAL PREPARATIONS FOR THE TREATMENT OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM PRINTED INSTRUCTIONAL, EDUCATIONAL AND TEACHING MATERIALS IN THE FIELD OF TREATMENT AND MANAGEMENT OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM PROVIDING MEDICAL INFORMATION IN THE FIELD OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM

54.

CONTRAVE

      
Application Number 005161211
Status Registered
Filing Date 2006-06-12
Registration Date 2007-05-16
Owner NALPROPION PHARMACEUTICALS LLC (USA)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 16 - Paper, cardboard and goods made from these materials
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical preparations for use in the treatment of obesity and inducing weight loss. Printed material, namely, brochures, newsletters, and bulletins on the topic of weight management and treatment of obesity. Medical information services, namely, providing health information in the field of weight management and the treatment of obesity.

55.

CONTRAVE

      
Application Number 130635600
Status Registered
Filing Date 2006-06-08
Registration Date 2010-05-05
Owner Nalpropion Pharmaceuticals LLC (USA)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

(1) Pharmaceutical preparations and substances for the treatment of obesity and inducement of weight loss. (2) Pharmaceutical preparations for use in the treatment of obesity and inducing weight loss.

56.

OREXIGEN

      
Application Number 004993441
Status Registered
Filing Date 2006-03-17
Registration Date 2007-03-15
Owner NALPROPION PHARMACEUTICALS LLC (USA)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical preparations and substances for the treatment of obesity, inducement of weight loss, and prevention of weight gain.

57.

OREXIGEN

      
Application Number 004993671
Status Registered
Filing Date 2006-03-17
Registration Date 2007-03-15
Owner NALPROPION PHARMACEUTICALS LLC (USA)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical preparations and substances for the treatment of obesity, inducement of weight loss, and prevention of weight gain.

58.

OREXIGEN

      
Application Number 129533500
Status Registered
Filing Date 2006-03-16
Registration Date 2008-12-08
Owner Nalpropion Pharmaceuticals LLC (USA)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

(1) Pharmaceutical preparations and substances for the treatment of obesity, inducement of weight loss, and prevention of weight gain.

59.

OREXIGEN

      
Application Number 129533600
Status Registered
Filing Date 2006-03-16
Registration Date 2008-12-08
Owner Nalpropion Pharmaceuticals LLC (USA)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

(1) Pharmaceutical preparations and substances for the treatment of obesity, inducement of weight loss, and prevention of weight gain.

60.

CONTRAVE

      
Serial Number 78979619
Status Registered
Filing Date 2006-01-06
Registration Date 2008-03-04
Owner NALPROPION PHARMACEUTICALS LLC ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical preparations for use in the treatment of obesity and inducing weight loss

61.

OREXIGEN THERAPEUTICS, INC.

      
Application Number 004744298
Status Registered
Filing Date 2005-11-16
Registration Date 2006-11-22
Owner NALPROPION PHARMACEUTICALS LLC (USA)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical preparations and substances for the treatment of obesity, inducement of weight loss and prevention of weight gain.

62.

OREXIGEN

      
Serial Number 78718907
Status Registered
Filing Date 2005-09-22
Registration Date 2008-03-11
Owner NALPROPION PHARMACEUTICALS LLC ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

PHARMACEUTICAL PREPARATIONS AND SUBSTANCES FOR THE TREATMENT OF OBESITY, INDUCEMENT OF WEIGHT LOSS, AND PREVENTION OF WEIGHT GAIN