Abstract

A pharmaceutical composition is provided including tamibarotene or a salt or analog thereof, a solubilizer, a permeation enhancer, a polymeric emulsifier, and a surfactant. In a further preferred embodiment, the pharmaceutical composition is in the form of a gel or cream, and provides a smooth composition to apply to the skin. The invention is further directed to methods of manufacturing the pharmaceutical composition and methods of treating a patient's skin with the pharmaceutical composition.

IPC Classes  ?

• A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
• A61K 31/327 - Peroxy compounds, e.g. hydroperoxides, peroxides, peroxy acids
• A61K 9/06 - OintmentsBases therefor

Abstract

The present invention comprises ternary compositions of tamibarotene and/or ammonium lactate in Pemulen for treatment of effects of aging.

IPC Classes  ?

• A61K 36/16 - Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
• A61K 8/42 - Amides
• A61K 8/365 - Hydroxycarboxylic acidsKetocarboxylic acids
• A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
• A61K 8/86 - Polyethers
• A61Q 19/08 - Anti-ageing preparations
• A61K 8/9771 - Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
• A61K 8/06 - Emulsions
• A61K 8/19 - Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
• A61K 8/34 - Alcohols
• A61K 8/37 - Esters of carboxylic acids

Abstract

The present invention comprises ternary compositions of tamibarotene and/or ammonium lactate in Pemulen for treatment of effects of aging.

IPC Classes  ?

• A61K 36/16 - Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
• A61K 8/42 - Amides
• A61Q 19/08 - Anti-ageing preparations
• A61K 8/365 - Hydroxycarboxylic acidsKetocarboxylic acids
• A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
• A61K 8/86 - Polyethers
• A61K 8/06 - Emulsions
• A61K 8/19 - Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
• A61K 8/34 - Alcohols
• A61K 8/37 - Esters of carboxylic acids
• A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof