Abstract

The present invention relates to a stable, synergistic composition for enhancing the solubility/dispersibility, bioavailability and immediate release of active compounds. The present invention also relates to a process for preparation of said synergistic composition.

IPC Classes  ?

• A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
• A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
• A61K 47/40 - CyclodextrinsDerivatives thereof
• A61K 47/46 - Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts

Abstract

A composition for enhancing the self-dispersion and bioavailability of phytochemicals includes (i) phytochemicals selected from carotenoids, stilbenoid, isoflavones, terpenes, isoquinoline alkaloids, phenolic compounds, saponins, flavonoids, quinones, fatty acids and their derivatives; and (ii) bio-enhancing agents/self-dispersing agents derived from extract of fresh plant parts selected from Curcuma longa (Turmeric); Beta vulgaris (Beetroot), Solanum tuberosum (Potato), Aloe barbadensis (Aloe vera), Daucus carota (Carrot), Mangifera indica (Mango), Manihot esculenta (Tapioca) and Cocos nucifera (Coconut) and bulb of Allium sativum (garlic). A process for preparation of the composition is also disclosed herein.

IPC Classes  ?

• A61K 36/9068 - Zingiber, e.g. garden ginger
• A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
• A61K 36/21 - Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
• A61K 36/81 - Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
• A61K 36/886 - Aloeaceae (Aloe family), e.g. aloe vera
• A61K 36/23 - Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
• A61K 36/22 - Anacardiaceae (Sumac family), e.g. smoketree, sumac or poison oak
• A61K 36/47 - Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
• A61K 36/889 - Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
• A61K 36/8962 - Allium, e.g. garden onion, leek, garlic or chives
• A61K 36/42 - Cucurbitaceae (Cucumber family)
• A61K 31/047 - Hydroxy compounds, e.g. alcoholsSalts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
• A61K 31/122 - Ketones having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
• A61K 31/4525 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
• A61K 31/19 - Carboxylic acids, e.g. valproic acid
• A61K 31/164 - Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
• A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
• A61K 31/357 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
• A61K 31/4375 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring hetero atom, e.g. quinolizines, naphthyridines, berberine, vincamine
• A61K 31/136 - Amines, e.g. amantadine having aromatic rings, e.g. methadone having the amino group directly attached to the aromatic ring, e.g. benzeneamine
• A61K 36/534 - Mentha (mint)
• A61K 31/593 - 9,10-Secocholestane derivatives, e.g. cholecalciferol, vitamin D3

Goods & Services

Medicinal, nutritional and pharmaceutical preparations and substances.

Goods & Services

Pharmaceuticals, medical and veterinary preparations; sanitary preparations for medical purposes; dietetic food and substances adapted for medical or veterinary use, food for babies; dietary supplements for human beings and animals; plasters, materials for dressings; material for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicides.

Abstract

A turmeric composition having enhanced self-dispersibility and bioavailability includes a solvent free, fresh turmeric rhizome extract and a dried turmeric rhizome extract (standardized to 35-95% total curcuminoids). The turmeric composition may be devoid of externally added excipients/bio-enhancing agents/dispersing agents. A process for preparation of the bioavailable turmeric composition is disclosed herein.

IPC Classes  ?

• A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
• A61K 31/12 - Ketones

Goods & Services

Medicinal herb extracts; Plant and herb extracts for medicinal purposes; Plant extracts for medical, veterinary and pharmaceutical purposes; Medicinal herbal extracts for medical purposes; Plant extracts for pharmaceutical purposes

Goods & Services

Medicinal, nutritional and pharmaceutical preparations and substances, namely, bioavailable nutraceutical preparations derived from garlic that support cardiovascular, blood pressure, cholesterol health and immune health

Abstract

Mucuna pruriens, Cynara cardunculus, Trigonella foenum graecum, Withania somnifera and L-arginine along with pharmaceutically acceptable excipients, having libido enhancing, testosterone levels increasing and ejaculation delaying properties. The present invention also disclosed herein a process for preparation of said composition.

IPC Classes  ?

• A61K 36/48 - Fabaceae or Leguminosae (Pea or Legume family)CaesalpiniaceaeMimosaceaePapilionaceae
• A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
• A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
• A61K 36/28 - Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
• A61K 36/38 - Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
• A61K 36/41 - Crassulaceae (Stonecrop family)
• A61K 36/63 - Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
• A61K 36/81 - Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
• A61K 36/8965 - Asparagus, e.g. garden asparagus or asparagus fern
• A61P 15/10 - Drugs for genital or sexual disordersContraceptives for impotence

Abstract

The present invention provides a process for preparing an herbal extract such that selective isolation of phytochemicals and resins in specific concentrations is obtained in the final herbal extract and compositions comprising the same. Further, the present invention provides a process for preparing an herbal extract comprising curcuminoids and resins, such that the extract is having high solubility/dispersibility, good bioavailability and efficient sustained release.

IPC Classes  ?

• A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
• A61K 31/12 - Ketones

Abstract

Curcuma longaBeta vulgarisSolanum tuberosumAloe barbadensisDaucus carotaMangifera indicaManihot esculentaCocos nuciferaCocos nucifera (Coconut); wherein said composition enhances the bioavailability of phytochemicals. The invention also disclosed herein a process for preparation of said composition.

IPC Classes  ?

• A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
• A61K 31/00 - Medicinal preparations containing organic active ingredients

Abstract

The invention disclosed herein is a turmeric composition having enhanced self-dispersibility and bioavailability comprising a fresh turmeric rhizome extract and dried turmeric rhizome extract (standardized to 35-95% total curcuminoids), and is devoid of any externally added excipients/bio-enhancing agents/dispersing agents. The invention also disclosed herein a process for preparation of said bioavailable turmeric composition.

IPC Classes  ?

• A61K 31/00 - Medicinal preparations containing organic active ingredients
• A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
• A61K 47/00 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient

Abstract

The invention disclosed herein is a turmeric composition having enhanced self-dispersibility and bioavailability comprising a fresh turmeric rhizome extract and dried turmeric rhizome extract (standardized to 35-95% total curcuminoids), and is devoid of any externally added excipients/bio-enhancing agents/dispersing agents. The invention also disclosed herein a process for preparation of said bioavailable turmeric composition.

IPC Classes  ?

• A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
• A61K 47/00 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient
• A61K 31/00 - Medicinal preparations containing organic active ingredients

Goods & Services

Medicinal, nutritional and pharmaceutical preparations and substances.

Abstract

The invention discloses a composition exhibiting enhanced bioavailability comprising tri-molecular complex of a natural compound or a natural compound containing component, a divalent or tri-valent metal ion and a phospholipid embedded in natural matrix. The composition of the invention further exhibits a sustained release profile for the natural compound or natural compound containing component. The invention further discloses a process for manufacturing the tri-molecular complex containing composition.

IPC Classes  ?

• A61K 31/12 - Ketones
• A61K 31/047 - Hydroxy compounds, e.g. alcoholsSalts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
• A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
• A61K 31/4375 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring hetero atom, e.g. quinolizines, naphthyridines, berberine, vincamine
• A61K 36/185 - Magnoliopsida (dicotyledons)
• A61K 36/28 - Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
• A61K 36/324 - Boswellia, e.g. frankincense
• A61K 36/38 - Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
• A61K 36/48 - Fabaceae or Leguminosae (Pea or Legume family)CaesalpiniaceaeMimosaceaePapilionaceae
• A61K 36/53 - Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
• A61K 36/54 - Lauraceae (Laurel family), e.g. cinnamon or sassafras
• A61K 36/81 - Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
• A61K 36/88 - Liliopsida (monocotyledons)
• A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
• A61K 36/9068 - Zingiber, e.g. garden ginger
• A61K 47/02 - Inorganic compounds
• A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
• A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids

Abstract

Mucuna pruriens, Cynara cardunculus, Trigonella foenum graecum, Withania somnifera Mucuna pruriens, Cynara cardunculus, Trigonella foenum graecum, Withania somnifera and L-arginine along with pharmaceutically acceptable excipients, having libido enhancing, testosterone levels increasing and ejaculation delaying properties. The present invention also disclosed herein a process for preparation of said composition.

IPC Classes  ?

• A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines

Goods & Services

Medicinal, nutritional and pharmaceutical preparations and substances.

Goods & Services

(1) Ginger extract for nutritional supplements; ginger rhizome extract for nutritional supplements

Goods & Services

Medicinal preparations for treating gastrointestinal diseases, nutritional supplements and pharmaceutical preparations for treating gastrointestinal diseases

Abstract

"PROCESS FOR PREPARING AN HERBAL EXTRACT AND COMPOSITIONS THEREOF" The present invention provides a process for preparing an herbal extract such that selective isolation of phytochemicals and resins in specific concentrations is obtained in the final herbal extract and compositions comprising the same. Further, the present invention provides a process for preparing an herbal extract comprising curcuminoids and resins, such that the extract is having high solubility/dispersibility, good bioavailability and efficient sustained release.

IPC Classes  ?

• A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines

Abstract

"PROCESS FOR PREPARING AN HERBAL EXTRACT AND COMPOSITIONS THEREOF" The present invention provides a process for preparing an herbal extract such that selective isolation of phytochemicals and resins in specific concentrations is obtained in the final herbal extract and compositions comprising the same. Further, the present invention provides a process for preparing an herbal extract comprising curcuminoids and resins, such that the extract is having high solubility/dispersibility, good bioavailability and efficient sustained release.

IPC Classes  ?

• A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines

Goods & Services

Medicinal, nutritional and pharmaceutical preparations and substances, namely, dietary supplements

Goods & Services

Scientific and technological services and research and design relating thereto; industrial analysis and research services. Medical services, veterinary services, hygienic and beauty care for human beings or animals.

Abstract

The present invention disclosed herein is a bile acid sequestering composition comprising the resin chelate with improved affinity/binding activity towards bile acid(s) and to the process for preparation thereof.

IPC Classes  ?

• C07D 265/08 - 1,3-OxazinesHydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
• A61K 31/74 - Synthetic polymeric materials
• A61K 33/06 - Aluminium, calcium or magnesiumCompounds thereof

Goods & Services

Scientific and technological services, namely, research and design relating thereto the field of medicinal and herbal products Medical services, veterinary services, hygienic and beauty care for human beings or animals

Goods & Services

Pharmaceutical, veterinary and sanitary preparations; dietetic substances adapted for medical use, food for babies; plasters, materials for dressings; materials for stopping teeth, dental wax; disinfectants; preparations for destroying vermin; fungicides, herbicides.

Goods & Services

Pharmaceutical, veterinary and sanitary preparations namely, pharmaceutical products for the prevention and treatment of cancer, pharmaceutical preparations and substances for the treatment of infectious diseases, blood disorders, pain, inflammation, sepsis, alopecia, obesity and cognitive disorders, antivirals, analgesics, antioxidants, veterinary vaccines, anti-infective products for veterinary use, pain relief medication, diagnostic preparations for veterinary purposes, sanitary towels, sanitary sterilizing preparations, sanitary preparations for medical purposes; dietetic substances adapted for medical use, namely, dietic sugar and sugar substitutes, dietetic foods and beverages and dietetic infusions for medical use, food for babies; medical and surgical plasters, materials for dressings, namely, sterilized dressings , wound dressings in the nature of pledgets, for dressing and gauge for dressings; materials for stopping teeth, dental wax; disinfectants; preparations for destroying vermin ; fungicides, herbicides

Abstract

The current invention discloses a bioavailable formulation for turmeric liquid oleoresin. The formulation as disclosed herein comprises of a turmeric liquid oleoresin in range of 0.1 to 99.8%; an essential oil, other than turmeric essential oil, in range of 1 to 98%, and an emulsifier in range of 1 to 98%. The formulation of invention further exhibits enhanced bioavailability and slow or sustained release of the turmeric oleoresin components.

IPC Classes  ?

• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
• A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines

Abstract

The invention discloses a novel composition for a natural compound. The composition described herein comprises of an natural active compound present in range of 0.01 – 98%; an essential oil present in range of 1 – 98%, and an emulsifier in range of 1 – 98%. Said composition exhibits an enhanced bioavailability and slow release of natural active compound.

IPC Classes  ?

• A61K 31/00 - Medicinal preparations containing organic active ingredients
• A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines