A hemodynamic monitor for detecting aortic stenosis includes a non-invasive blood pressure sensor and an integrated hardware unit with a system processor, a system memory, and a display with a user interface. The system memory includes instructions that, when executed by the system processor, are configured to adjust, by a pressure controller, a pressure within an inflatable blood pressure bladder. An arterial pressure waveform data of the patient is generated based on the adjusted pressure within the inflatable blood pressure bladder over the period of time and a plurality of signal measures are extracted from the arterial pressure waveform data of the patient. Input features are extracted from the plurality of signal measures that are indicative of an aortic stenosis score of the patient, and the aortic stenosis score of the patient is determined based on the extracted input features.
A priming valve includes a fluid flow path, a fluid inlet configured to couple to a fluid outlet of a fluid channel including at least one sensor configured to characterize at least one attribute of a fluid, a fluid outlet, a valve seat, and a connector. The connector engages the valve seat to prevent fluid flow via the fluid flow path. The connector is configured to move relative to the valve seat in response to a threshold pressure within the fluid flow path to allow the fluid to flow via the fluid flow path. A flow sensor sub-assembly for sensing flow of a fluidic medicament may include a priming valve and at least one sensor of a fluid port configured to characterize at least one attribute of a fluid within an administrable fluid source. A method for readying a fluid sensor may use a priming valve.
G01F 15/00 - Details of, or accessories for, apparatus of groups insofar as such details or appliances are not adapted to particular types of such apparatus
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
A61M 5/168 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
F16K 31/12 - Operating meansReleasing devices actuated by fluid
G01F 1/66 - Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow by measuring frequency, phase shift or propagation time of electromagnetic or other waves, e.g. using ultrasonic flowmeters
A biometric sensor may include a scanner configured to capture a biometric data and an adjustment mechanism configured to respond to a force applied to the biometric sensor by shifting the biometric sensor from a neutral position to an adjusted position. The adjustment mechanism may be configured to respond to the removal of the force by returning the biometric sensor to the neutral position. While the biometric sensor is in the neutral position, the scanner may be capable of capturing a biometric data of a majority of users interacting with the apparatus. Accordingly, the biometric sensor may be able to operate with minimal adjustments. The biometric sensor may be part of a dispensing cabinet such that the biometric data captured by the biometric sensor may be used to control access to the dispensing cabinet. Related methods are also disclosed.
G06V 10/12 - Details of acquisition arrangementsConstructional details thereof
G06V 10/98 - Detection or correction of errors, e.g. by rescanning the pattern or by human interventionEvaluation of the quality of the acquired patterns
G06V 40/00 - Recognition of biometric, human-related or animal-related patterns in image or video data
G07F 11/52 - Coin-freed apparatus for dispensing, or the like, discrete articles from movable storage containers or supports the storage containers or supports being rotatably mounted about horizontal axes
G16H 20/13 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers
A medical device controller operating in conjunction with a medical device determines one or more current versions of executable code associated with one or more processors in a medical device. Medical devices may include infusion pumps, other patient treatment devices as well as vital signs monitors. The medical device controller determines one or more current versions of executable code and configuration information associated with the one or more processors in the medical device. The medical device controller further determines which of the processors in the medical device require updated executable code, and which of the processors in the medical device require updated configuration information. The medical device controller distributes to the medical device as required at least one of the updated executable code and the updated configuration information. The medical device deploys the distributed updates, and activates the updates at a clinically appropriate time.
H04L 67/12 - Protocols specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/02 - Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
A61B 5/08 - Measuring devices for evaluating the respiratory organs
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
G16H 10/00 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
H04L 67/00 - Network arrangements or protocols for supporting network services or applications
H04L 67/10 - Protocols in which an application is distributed across nodes in the network
A coupler including a first connector having a first end, a second end opposite the first end, and a valve disposed between the first end and the second end. The second end including a mating portion, wherein the valve extends at least partially into the mating portion. The coupling including a second connector having a housing, a plurality of flanges extending from the housing, each of the plurality of flanges being separated from an adjacent flange by a cut. The plurality of flanges configured to engage with the mating portion when the second connector is coupled to the first connector. The first connector is configured to decouple from the second connector in response to a pullout force exceeding a predetermined threshold force.
F16L 37/46 - Couplings of the quick-acting type with fluid cut-off means with fluid cut-off means in only one of two pipe-end fittings with a gate valve or sliding valve
An infusion control device detects a patient-controlled drug-requesting device that is in operable communication with the infusion control device. The infusion control device identifies sensor devices and drug-delivery apparatuses separate from the infusion control device that are in operable communication with the infusion control device. The infusion control device selects a drug-control algorithm for approving drug requests received by the patient-controlled drug-requesting device. The infusion control device identifies a patient using the patient-controlled drug-requesting device, and receives patient physiological data from the sensor devices. The infusion control device receives a request for a drug to be delivered to the patient by a drug-delivery apparatus. The infusion control devices determines whether the patient is authorized to perform the drug request. And based on determining that the patient is authorized, the infusion control device causes delivery of the drug to the patient.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
7.
METHOD AND SYSTEM FOR MODULAR CONNECTIONS WITH ELECTRICAL COMPONENTS
An electronic module for a modular patient care system is disclosed. The electronic module can include a housing having an attachment side configured to releasably attach to an adjacent electronic module. A latch mechanism can be configured to engage a catch member on the adjacent electronic module to secure the attachment side to the adjacent electronic module. An electrical connector positioned on the attachment side can be configured to electrically connect to an adjacent electrical connector on the adjacent electronic module. A sensor coupled to the housing can be configured to detect movement of the latch mechanism indicative of at least one of engagement or disengagement of the latch mechanism from the adjacent electronic module.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
Provided herein is a load spring washer configured for use with a medical injection device, having a main body having a proximal surface and a distal surface and one or more protrusions extending proximally away from the proximal surface of the main body.
An infusion device includes a fluid pump and a processor. The processor is configured to determine an amount of fluid pumped by the fluid pump or an amount of time the fluid pump has pumped the fluid. The processor is also configured to determine that the amount of fluid satisfies a volume threshold or that the amount of time satisfies a duration threshold. Additionally, the processor is configured to, responsive to determining that the amount of fluid satisfies the volume threshold or that the amount of time satisfies the duration threshold, electronically transmit a request for a medical test and initiate a timer. Further, the processor is configured to determine an adjustment-delay threshold prior to an initiation or a completion of the medical test. Moreover, the processor is configured to reduce an operating speed of the fluid pump when the timer satisfies the adjustment-delay threshold.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
10.
MEDICAL DEVICE WITH UNIDIRECTIONALLY VALVED RECIPROCATING PISTON PUMP AND DISCRETE DOSE DUPLICATION AND TIMING FOR RECIPROCATING PISTON PUMP
A medical device including a reservoir, a patient cannula, and a fluid path connecting the reservoir and the patient cannula. The device also includes a first one-way valve, a reciprocating piston mechanism, and a second one-way valve disposed sequentially on the fluid path between the reservoir and the patient cannula.
A cell sorting system that automatically generates a sorting strategy based on examples of target events provided by an operator. The target events can be selected using measurements ranging from traditional flow cytometry measurements to derived measurements that are computationally expensive to complex measurements such as images.
A syringe assembly includes a syringe barrel (12) having a proximal end and a distal end, a needle hub (20) supporting the needle and coupled to the distal end of the syringe barrel (12). A moveable shield (36) is included for sliding from a first position where the needle is exposed a first length, a second position where the needle is exposed a second length less than said first length, and a third position covering a distal end of the needle. A locking mechanism (48, 86) is included to retain the shield in the second position while enabling the shield to slide to the third position, and to lock the shield in the third position to prevent re-use of the syringe.
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
A61M 5/46 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for controlling depth of insertion
An infusion module adapter system couples a control unit of a patient care system to an infusion pump. The adapter system includes a first interconnect system on a first side and a second interconnect system on a second side. The first interconnect system includes a mechanical connector having first support contacts for mechanical coupling to the control unit; and a logical connector having first power contacts and first communication contacts for logical coupling to the control unit. The second interconnect system includes an integrated connector having second support contacts, second power contacts, and second communication contacts for mechanical coupling and logical coupling to the infusion pump. The adapter system further includes power conversion circuitry configured to convert a power signal between the first power contacts and the second power contacts, and processing circuitry configured to convert messages between the first communication contacts and the second communication contacts.
A fillable medicament delivery device, including a body, a reservoir disposed on the body and having an end wall, and a plunger movably disposed within the reservoir. The device also includes an input port and an output port disposed on one of the end wall and the plunger, and a patient cannula fluidly connected with the output port. The one of the end wall and the plunger has a face oriented toward an interior of the reservoir and the remaining one of the end wall and the plunger, and the face has a channel recessed therefrom. The channel fluidly connects the input port and the output port.
A61M 5/315 - PistonsPiston-rodsGuiding, blocking or restricting the movement of the rodAppliances on the rod for facilitating dosing
A61M 5/38 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests with means for eliminating or preventing injection or infusion of air into body using hydrophilic or hydrophobic filters
A coupler including a first connector having a first end, a second end opposite the first end, and a valve disposed between the first end and the second end. The second end including a mating portion, wherein the valve extends at least partially into the mating portion. The coupling including a second connector having a housing, a plurality of flanges extending from the housing, each of the plurality of flanges being separated from an adjacent flange by a cut. The plurality of flanges configured to engage with the mating portion when the second connector is coupled to the first connector. The first connector is configured to decouple from the second connector in response to a pullout force exceeding a predetermined threshold force.
Disclosed herein is a blood pressure monitor component for monitoring a patient's blood pressure including: a cuff connected to a rack which includes a series of apertures along at least one end of the cuff, wherein the cuff includes a bladder; a pinion capable of engaging with the series of apertures of the rack; and a force sensor configured to sense tension applied by the cuff. The blood pressure monitor component may include a light source and a light sensor which are integrated within the cuff. The light source may be configured to output light which is received by the light sensor. The amount of light which is received by the light sensor corresponds to the blood pressure.
Branched tandem dye scaffolds are provided. Embodiments of the invention include: a non-conjugated backbone comprising a branch comprising two or more donor fluorophores; and an acceptor fluorophore(s) linked to the non-conjugated backbone; wherein the acceptor fluorophore(s) and the donor fluorophores are in energy transfer relationship. Also provided are methods of making and using the branched tandem dye scaffolds, as well as kits that include the branched tandem dye scaffolds that find use in embodiments of the methods.
C08G 69/40 - Polyamides containing oxygen in the form of ether groups
C08G 69/48 - Polymers modified by chemical after-treatment
C09B 69/10 - Polymeric dyesReaction products of dyes with monomers or with macromolecular compounds
G01N 33/533 - Production of labelled immunochemicals with fluorescent label
G01N 33/542 - ImmunoassayBiospecific binding assayMaterials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances
An infusion control test system includes a patient bio-simulator configured to generate first simulated biophysical data; an infusion control system configured to determine a first infusion profile in response to the first simulated biophysical data; and an infusion pump simulator configured to simulate a first administration of medication according to the first infusion profile. The patient bio-simulator is further configured to: simulate a patient response to the simulated first administration of medication; and generate second simulated biophysical data by adjusting the first simulated biophysical data according to the patient response.
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
The disclosure relates to an automatic injection device including a body; a medical container including finding a barrel containing a product for injection, a distal tip provided with an injection needle and a stopper in sliding engagement within the barrel, the medical container being slidably arranged in the body between a proximal position and a distal position; a safety shield slidably mounted within the body between a distal initial position and a proximal second position; a plunger rod slidably arranged in the body, the plunger rod including a proximal flange releasably locked in a proximal initial position by at least one flexible arm of the body, the plunger rod being movable in a distal direction when the proximal flange is unlocked to engage the stopper; a cam cooperating with the safety shield so that a translation of the safety shield from the distal initial position to the proximal second position causes the cam to rotate within the body to an unlocking position; an activator slidably mounted at a proximal end of the body, the activator cooperating with the cam so that a rotation of the cam to the unlocking position causes the activator to move in the distal direction. In the initial position, the activator is proximally spaced from the flexible arms and, when the cam is in the unlocking position, the activator causes the flexible arms to deflect outwardly to release the proximal flange of the plunger rod, thereby allowing the plunger rod to move in the distal direction to push the medical container.
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/315 - PistonsPiston-rodsGuiding, blocking or restricting the movement of the rodAppliances on the rod for facilitating dosing
A61M 5/46 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for controlling depth of insertion
21.
SECURE SMART CONTAINER ASSEMBLY, SYSTEMS, AND METHODS
A mobile smart container system comprises a housing, an access component configured to secure access to a compartment within the housing when in a closed position, a communication interface configured to wirelessly receive a request to access the compartment, a perceivable output device, an electromechanical latch configured to engage with the access component to releasably lock the access component in the closed position, and a processor. The processor receives and authenticates the request to access the compartment and, in response to receiving and authenticating the request, activates the electromechanical latch to unlock the access component to make the compartment accessible, and outputs, upon actuation of the electromechanical latch, an alert via the perceivable output device to identify the smart container system.
G06Q 10/087 - Inventory or stock management, e.g. order filling, procurement or balancing against orders
B65D 21/02 - Containers specially shaped, or provided with fittings or attachments, to facilitate nesting, stacking, or joining together
B65D 43/22 - Devices for holding in closed position, e.g. clips
B65D 43/26 - Mechanisms for opening or closing, e.g. pedal- operated
E05B 47/00 - Operating or controlling locks or other fastening devices by electric or magnetic means
G07C 9/00 - Individual registration on entry or exit
G16H 20/13 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers
An automatic injection device for injecting fluid in a syringe to an injection site is disclosed. The syringe includes a cartridge, a needle at a first end of the cartridge, and a element movable within the cartridge capable to inject fluid within the cartridge into the injection site. The automatic injection device includes a syringe loading mechanism for loading and fixing the syringe, a syringe driving mechanism having a first motor and a first actuation assembly capable of moving the syringe loading mechanism in a first direction towards the injection site of the target to insert the needle of the syringe into the injection site of the target. A dose control mechanism includes a second motor and a second actuation assembly for moving the movable element of the syringe towards the first end of the cartridge to expel a predetermined dose of fluid from the cartridge into the injection site.
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/315 - PistonsPiston-rodsGuiding, blocking or restricting the movement of the rodAppliances on the rod for facilitating dosing
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
23.
CALIBRATION AND DESIGN OF AN AUTOMATED DIAGNOSTIC ANALYZER
An analyzer for analysis of a biological sample prepared by a pre-analytical system and a method of operating an analyzer that receives biological samples for processing. The analyzer is automated and has a housing in which the biological samples are processed for analysis. The analyzer has an inventory control system for consumables used in the analyzer. The consumables are stored on and below a processing deck in the analyzer. The inventory control system can include racks for selectively storing consumables below deck, machine-readable labels on the processing deck for managing consumables thereon, and a support plate for the sample processing plates that manage waste from the processing plates. The analyzer includes an inventory robot disposed in the housing that includes an inventory scanner and an end-effector that is configured to handle a variety of consumables and is used for calibration.
Disclosed are systems and methods for a computerized framework that electronically manages and controls a patient's therapy for proper administration of diabetic treatment. The framework includes a disposable pen injector that has integrated therein dose logging capabilities (e.g., a NFC circuit) for controlling the administration of the prescribed therapy. Electronic communications between the disposable pen injector and a therapy control application executing on a patient's device can effectuate accurate and efficient administration of prescribed therapy. The pen can communicate information to the patient's device, and the application executing thereon, that includes dosage information related to availability left in the pen, timing of doses, and the like. In a related manner, the application can compile dosage planning information that can dictate types of doses, amounts of doses, timing of doses, and the like, to ensure that the patient is complying with a prescribed diabetic prescription.
A flush syringe and integrated swab assembly comprises a chamber and a tip having a passageway. The assembly includes a plunger rod and an integral swab including an integral collar extending from the distal wall of the barrel, surrounding the distal tip, and having a collar distal end and a collar proximal end, the integral collar including at least one sidewall having an inside surface including an inner thread thereon defining a Luer lock area and configured to connect to the hub of a vascular access device connector, the at least one sidewall further having an outside surface including an outer thread thereon configured for connection to the removable cap that when connected to the integral collar covers the integral collar to protect the distal tip and the collar from contamination, and a porous hollow mass connected to the inner thread of the integral collar.
A fillable medicament delivery device, including a body, a reservoir disposed on the body and having an end wall, and a plunger movably disposed within the reservoir. The device also includes an input port and an output port disposed on one of the end wall and the plunger, and a patient cannula fluidly connected with the output port. The one of the end wall and the plunger has a face oriented toward an interior of the reservoir and the remaining one of the end wall and the plunger, and the face has a channel recessed therefrom. The channel fluidly connects the input port and the output port.
An automatic injection device including a body; a medical container including a barrel containing a product for injection, a distal tip provided with an injection needle and a stopper in sliding engagement within the barrel, the medical container being slidably arranged in the body between a proximal position and a distal position; a safety shield slidably mounted within the body between a distal initial position and a proximal second position; a plunger rod slidably arranged in the body from a releasably locked proximal initial position in which a distal tip of the plunger rod is proximally spaced from the stopper, the distal tip of the plunger rod being adapted push the stopper in the distal direction when the plunger rod is unlocked; a cam cooperating with the safety shield so that a translation of the safety shield from the distal initial position to the proximal second position causes the cam to rotate within the body to an unlocking position; a plunger retainer including at least one elastic lever including at least one retention member, the plunger retainer cooperating with the cam so that, in the initial position, each retention member lockingly engages the plunger rod and, when the cam is in the unlocking position, the lever is deflected to disengage each retention member from the plunger rod, thereby allowing the plunger rod to move in the distal direction to push the medical container.
Fluid connectors assemblies that provide neutral fluid displacement without overlapping connectors are disclosed. A fluid connector assembly may include a housing and a pair of connectors (e.g., luers) coupled with the housing. A compressible member is located within the housing. The first connector and the second connector each include a post with an opening. The compressible member can seal off the opening of the first connector from fluid entry. However, when the post of the second connector is inserted into the housing, the post of the second connector displaces the compressible member, causing the compressible member to create a fluid path, thereby allowing fluid to flow through the internal volume of the housing. Further, the compressible member seals the housing until each of the first connector and the second connector are coupled therewith forming a fluid path through the posts.
A medical device such as an infusion system detects that an accessory has been coupled to the device. The medical device initially operates in a first mode of operation. The medical device, in response to the detecting, associates the accessory with a different mode of operation for the medical device that requires changes to at least one of the operating parameters for the infusion system or elements within a graphical user interface. The medical device then automatically changes the mode of operation from the first mode of operation to the associated different mode of operation to reflect the coupling of the accessory to the infusion system. Related apparatus, systems, techniques and articles are also described.
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
A61M 16/00 - Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators Tracheal tubes
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
A system may include a data processor and a memory storing instructions. The instructions may result in operations when executed by the data processor. The operations may include determining, based on location data from a positioning system, a presence of a cartridge at a location. The cartridge may include a substance. A quantity of the substance may be determined based on content data from a content meter at the location. Diversion of the substance may be detected based on the cartridge being present at the location and/or the quantity of the substance. Related methods and articles of manufacture, including apparatuses and computer program products, are also disclosed.
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
A61M 5/24 - Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
in vitro diagnostic reagents for medical use and assay kits for medical use comprising medical diagnostic reagents and assays for the detection of diseases, namely, cancer and HPV
A catheter system may include a catheter hub, a septum disposed within the catheter hub, a catheter tube extending from the catheter hub, a needle hub, and an introducer needle secured within the needle hub. The catheter hub may include a push tab and one or more ribs, which may extend outwardly from an upper surface of the catheter hub. The ribs may be shorter in height than the push tab and/or may be generally parallel to the push tab. The introducer needle may include a flashback notch. In response to insertion of the introducer needle into vasculature, blood may flow into the introducer needle, through the flashback notch, and into a flashback chamber disposed between the septum and the catheter tube. The flashback chamber may be disposed distal to the push tab and the ribs, which may improve visualization of the flashback chamber by a user.
The technology described herein generally relates to pump assemblies. The pump assemblies can include a housing, a pump, a suction flow path, a pressure flow path, and a relief valve. The pump can comprise a suction port and a pressure port. The suction flow path can fluidically connect a suction output of the pump assembly to the suction port. The pressure flow path can fluidically connect a pressure output of the pump assembly to the pressure port. The pressure flow path can comprise a reservoir, a first conduit fluidically connecting the pressure port to the interior volume via a first opening of the reservoir, a filter, and a second conduit fluidically connecting the interior volume to the pressure output via a second opening of the reservoir. The relief valve can be configured to exhaust gas and moisture from the interior volume via a third opening of the reservoir.
Needle-free connectors having a housing with an cavity and center-post, and valves having a head and a skirt are disclosed where the valve is positioned within the cavity of the housing with the center-post extending into a passage through the valve, and the skirt extending away from the head of the valve to the housing to fluidly separate the cavity into a first portion and a second portion, and where an outer end of the skirt is spaced apart from an end of the cavity to permit the valve to move between a closed configuration and an open configuration such that, in the open configuration, the skirt extends along the head and in a direction toward a first housing port, and as the valve moves from the open configuration toward the closed configuration, a volume of the first portion of the cavity decreases to expel any fluid accumulated therein.
An electronic medical storage cabinet includes a plurality of drawers configured with a plurality of sensors arranged to identify a positioning of storage pockets within the drawers. Upon receiving an indication of a new medicine container to be loaded in the cabinet, a sequence of steps to load the medicine container into the cabinet is generated based on a mapping algorithm. A first step is displayed on a display the cabinet, and a determination is made as to whether the first step is associated with one of the plurality of drawers. In response to determining that the first step is associated with one of the plurality of drawers, the drawer is automatically unlocked. In response to determining that the first step is successfully completed, a determination of whether execution of any additional steps is pending and indicated on the display.
G06Q 10/0631 - Resource planning, allocation, distributing or scheduling for enterprises or organisations
A47B 67/02 - Cabinets for shaving tackle, medicines, or the like
G05B 15/02 - Systems controlled by a computer electric
G06F 21/30 - Authentication, i.e. establishing the identity or authorisation of security principals
G06Q 10/087 - Inventory or stock management, e.g. order filling, procurement or balancing against orders
G07C 9/00 - Individual registration on entry or exit
G07C 9/38 - Individual registration on entry or exit not involving the use of a pass with central registration
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
A gravimetric verification system, method, and computer program product for automated detection and correction of reference density information based. An expected density of a fluid drug can be determined from the measured mass of a fluid drug and the intended volume of the fluid drug to be delivered to a medication container. The expected density can be compared to previously calculated densities for the fluid to verify the accuracy of a reference density value, verify the measurements and functional status of the measuring device for the fluid drug, and, in some instances, provide control or configuration commands to adjust one or more devices.
G16H 20/13 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
37.
ROBOTIC DRUG DELIVERY SYSTEM FOR MEDICAL FACILITIES
Methods, devices, and systems are described for a robotic drug delivery system. The robotic drug delivery system includes either an overhead track situated overhead of a floor space at a medical facility. The overhead track extends between a pharmacy terminal at the medical facility and a remote site at the medical facility. The robotic drug delivery system includes either a motorized platform, a motorized carousel, or a motorized cart configured to travel along the overhead track. The robotic drug delivery system includes a processor configured to instruct the motorized platform, the motorized carousel, or the motorized cart to move a transportable dispenser from the remote site to the pharmacy terminal along the overhead track. The transportable dispenser is configured to dispense the medication at the remote site at the medical facility.
G16H 20/13 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G06Q 10/087 - Inventory or stock management, e.g. order filling, procurement or balancing against orders
G16Z 99/00 - Subject matter not provided for in other main groups of this subclass
B65G 1/137 - Storage devices mechanical with arrangements or automatic control means for selecting which articles are to be removed
B65G 35/00 - Mechanical conveyors not otherwise provided for
B65G 47/04 - Devices for feeding articles or materials to conveyors for feeding articles
Needle-free connectors having a housing with an cavity and center-post, and valves having a head and a skirt are disclosed where the valve is positioned within the cavity of the housing with the center-post extending into a passage through the valve, and the skirt extending away from the head of the valve to the housing to fluidly separate the cavity into a first portion and a second portion, and where an outer end of the skirt is spaced apart from an end of the cavity to permit the valve to move between a closed configuration and an open configuration such that, in the open configuration, the skirt extends along the head and in a direction toward a first housing port, and as the valve moves from the open configuration toward the closed configuration, a volume of the first portion of the cavity decreases to expel any fluid accumulated therein.
A medication delivery device comprising a base plate engaging a cover to form an interior, the interior including a pump drive mechanism for driving medication through the device, a drivetrain engaged to the pump drive mechanism, a magnetic encoder including an encoder hub mechanically coupled to the drivetrain, the encoder hub including a magnet, and a sensor that measures a magnetic field from the magnet to determine a rotational position of the drivetrain.
A catheter system may include a catheter adapter, a catheter extending distally from the distal end of the catheter adapter, and a needle hub coupled to the catheter adapter. The needle hub may be transparent, and a needle may be secured within the needle hub. The catheter system may also include a flow control plug coupled to the proximal end of the needle hub. In some embodiments, a flashback pathway may be disposed between an outer surface of the flow control plug and an inner surface of the needle hub. In some embodiments, the catheter system may include an inner barrel and an outer barrel, and the inner barrel and the needle hub may be configured to move proximally within the outer barrel to retract the needle. The flashback pathway may be disposed between an outer surface of the needle hub and an inner surface of the inner barrel.
A holding device configured to support medical containers includes a supporting plate having a first surface, a second surface, a peripheral edge between the first surface and the second surface, and a plurality of openings through the supporting plate configured to receive the medical containers. The surfaces of the supporting plate include a peripheral lower portion extending inward from the peripheral edge; at least one upper portion enclosed by the peripheral lower portion; and at least one upwardly angled portion extending between the lower portion and the upper portion. The holding device further includes a plurality of chimneys protruding from the first surface and/or the second surface of the supporting plate at least partially enclosing the plurality of openings, such that the plurality of chimneys guide insertion of the medical containers into the plurality of openings.
A device for obtaining confirmation of completion of disinfection includes an electrically activated light source. The device further includes at least one enclosure having walls formed of a diffusion control membrane and enclosing a salt, which is soluble in a disinfectant used for the disinfection. The at least one enclosure and the light source are electrically connected in series.
A connector including a housing having a first end and second end opposite the first end, the housing having an interior space, a luer assembly disposed within the interior space of the housing, the luer assembly having a locking ring and the luer assembly configured to couple to a coupling device to secure the coupling device to the connector, and a sleeve at least partially disposed around the luer assembly and disposed within the interior space, the sleeve configured to couple to the locking ring to prevent axial movement of the sleeve relative to the luer assembly and the housing. The housing being rotatable to the luer assembly and the sleeve when the sleeve is coupled to the locking ring to prevent decoupling of the luer assembly from the coupling device when the luer assembly is coupled to the coupling device.
F16L 37/53 - Couplings of the quick-acting type adjustableCouplings of the quick-acting type allowing movement of the parts joined allowing adjustment or movement only about the axis of one pipe
F16L 37/098 - Couplings of the quick-acting type in which the connection between abutting or axially-overlapping ends is maintained by locking members combined with automatic locking by means of flexible hooks
A connector including a housing having a first end and second end opposite the first end, the housing having an interior space, a luer assembly disposed within the interior space of the housing, the luer assembly having a locking ring and the luer assembly configured to couple to a coupling device to secure the coupling device to the connector, and a sleeve at least partially disposed around the luer assembly and disposed within the interior space, the sleeve configured to couple to the locking ring to prevent axial movement of the sleeve relative to the luer assembly and the housing. The housing being rotatable to the luer assembly and the sleeve when the sleeve is coupled to the locking ring to prevent decoupling of the luer assembly from the coupling device when the luer assembly is coupled to the coupling device.
ABSTRACT A device for accommodating and magnetizing a tissue-penetrating medical device of various lengths, with or without a cover covering a portion or the entirety of the tissuepenetrating medical device, is disclosed including a sleeve member having an open proximal end, a distal end, an inner surface, an outer surface having a graduated injection depth gauge to indicate needle penetration depth when the cover is placed into a magnetizer, and a hollow body extending between the proximal end and the distal end to form a protective closure over a shaft of a tissue-penetrating medical device. Also disclosed is a needle cover having a fixed distance between the tip of the needle and the tip of the needle cover. A device having one or more magnetizing elements sectioned into a plurality of movable segments pivoting around an axis to accommodate needles with different lengths is also disclosed. Also disclosed is a device having one or more magnetizing means mounted on a movable element to magnetize needles of various lengths.
46.
FLUID DELIVERY DEVICE WITH ACTIVE SAFETY FUNCTION FOR DETECTION AND CONFIRMATION OF ANOMALOUS WIRELESS COMMANDS FROM AUXILIARY DEVICE
A fluid delivery device (FDD) has a reservoir, a driver assembly, and a controller to controllably deliver fluid from the reservoir into a patient. The controller is configured to support dosing control and other operations of the fluid delivery device by a connected auxiliary device such as a smartphone or other portable remote control device. Active safety features are provided for commands to the fluid delivery device that comprise: (1) at least anomaly detection for inputted FDD commands and prompt for confirmation of anomalous commands prior to commanded operation of the FDD; and (2) an optional secondary communication path or modality for the confirmation that is different from a first communication path or modality used to communicate the command to the FDD.
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
Provided herein is a terminally-sterilizable package for a medical device having a first flexible web having a proximal end, a distal end, and at least one side therebetween defining a first perimeter, and a second flexible web having a proximal end, a distal end, and at least one side therebetween defining a second perimeter at least partially overlapping with the first perimeter at one or more sealing regions, the second flexible web removably attached to the first flexible web, the first flexible web and the second flexible web defining a compartment configured to hold the medical device, wherein the one or more sealing regions define a tortuous path fluidly connecting the compartment with an exterior of the package.
A61B 50/30 - Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
48.
MANUAL METHOD FOR DEPOSITING A SAMPLE DIRECTLY ONTO A SLIDE FOR LIQUID BASED CYTOLOGY
A biological sample is provided, wherein the biological sample is a liquid-based cytology sample. A slide is placed in a holder. The slide is pre coated with a composition that will cause cells to adhere to the slide. A settling chamber is placed over the slide and the settling chamber is locked onto the holder. The settling chamber has openings in both proximate and distal ends. The opening in the distal end of the settling chamber is positioned over the slide. A density reagent is then dispensed into the settling chamber. The liquid-based cytology sample is then dispensed into the settling chamber over the reagent. The assembly formed by the holder, slide and settling chamber (and its liquid contents) is placed in a centrifuge. The density reagent and the liquid thereover are decanted from the settling chamber. The settling chamber is removed from over the slide.
Methods, apparatus, and systems to non-invasively determine intra-luminal placement and patency of a vascular access device. Patency and/or placement are estimated indirectly by measuring a physiological parameter which is indicative of proper patency and/or placement of the vascular access device in a patient. The measurement is compared to a reference value or calibration. If the comparison indicates indication of proper patency and/or placement, a signal can be generated. The signal can be used in a number of ways. One example is to give a user-perceivable alarm or indication of proper patency and/or placement. Non-limiting examples include activating a light, an audible buzzer, a vibration, readable displayed text or graphics, or some combination of the same. The user can then have an indirect and at least semi-automatic way of estimating proper patency and/or placement of a vascular access device.
A61B 5/02 - Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/0215 - Measuring pressure in heart or blood vessels by means inserted into the body
A61B 5/06 - Devices, other than using radiation, for detecting or locating foreign bodies
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61B 5/1459 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
The invention relates to a medical injection device having: a barrel having an inner surface; a stopper in gliding engagement with the barrel; and a pharmaceutical composition within the medical injection device and in contact with the inner surface of the barrel, the inner surface of the barrel comprising a coating of plasma treated silicone oil in contact with the composition, wherein the plasma treatment of silicone oil reduces the number of particles present on the surface of the coating and the number of particles released into the pharmaceutical composition contained in the medical injection device as compared to silicone oil that is not plasma treated.
A device for obtaining confirmation of completion of disinfection includes an electrically activated light source. The device further includes at least one enclosure having walls formed of a diffusion control membrane and enclosing a salt, which is soluble in a disinfectant used for the disinfection. The at least one enclosure and the light source are electrically connected in series.
G01N 27/04 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
A needle cap for an injector pen including a body having a closed end and an open end and a protrusion extending from the closed end for indicating that a needle will not pass through the closed end.
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
A61M 5/50 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
The disclosure provides a system and method to safely and efficiently store and transport process tubes in a carrier tray comprising prior to and during amplification of nucleotides in the process tubes. The process tube disclosed includes a securement region having an annular ledge, a neck, and a protrusion. The securement region of the process tube can secure the process tube in a port of the carrier tray, but still allows the process tube to adjust or float in order to align the process tube into a rigid heater well of a thermal cycler.
Syringes are described herein. A syringe includes a syringe body, a first plunger, a biasing member, and a retention member. The syringe body defines a syringe cavity and a syringe port, wherein the syringe port is in fluid communication with the syringe cavity. The first plunger comprises a first plunger shaft extending from the first plunger, the first plunger disposed within the syringe cavity and defining a first chamber in the syringe cavity, wherein the first chamber is in fluid communication with the syringe port. The biasing member is coupled to the first plunger shaft, wherein the biasing member urges the first plunger to advance toward the syringe port. The retention mechanism prevents the biasing member from advancing the first plunger in an engaged position and permits the biasing member to advance the first plunger in a released position.
The present technology provides for a microfluidic substrate configured to carry out PCR on a number of polynucleotide-containing samples in parallel. The substrate can be a single-layer substrate in a microfluidic cartridge. Also provided are a method of making a microfluidic cartridge comprising such a substrate. Still further disclosed are a microfluidic valve suitable for use in isolating a PCR chamber in a microfluidic substrate, and a method of making such a valve.
The disclosure provides driver components and methods of operating same that provide a reduced form factor for pen-type injection devices. In particular, various multi-piece telescoping plunger rod configurations are disclosed that can be implemented within pen-type injection devices to achieve such improvements. Driver components replace a single plunger rod having fixed length with telescoping pieces that are controlled to at least partially extend axially to dispense fluid from the reservoir or cartridge.
Aspects of the present disclosure include methods for determining baseline noise of a photodetector (e.g., in a light detection system of a particle analyzer). Methods according to certain embodiments include irradiating a sample having particles in a flow stream, detecting light with the photodetector from the irradiated flow stream, generating data signals from the detected light and calculating a moving average mean squared error of the generated data signals to determine the baseline of the photodetector. Systems (e.g., particle analyzers) having a light source and a light detection system that includes a photodetector for practicing the subject methods are also described. Integrated circuits and non-transitory computer readable storage medium are also provided.
Multiple lumen intravenous tubing systems can include multi-lumen tubing that can be coupled with a manifold, where the multi-lumen tubing includes multiple lumens extending within the tubing and which are fluidly coupled with counterpart fluid flow paths of the manifold when the multi-lumen tubing is connected to an outlet of the manifold, and where the manifold includes more than one inlet and an outlet with each inlet fluidly coupled to a respective fluid flow paths that can be fluidically separated from the other fluid flow paths of the manifold to permit directing a first fluid from through the manifold and multi-lumen tubing, and a second fluid through the manifold and multi-lumen tubing, without the first and second fluids intersecting.
A tubing junction assembly may include a body, and a collar coupled to the body. The body may include a head portion, a base portion, and an intermediate portion. At least a portion of an outer surface of the body at the intermediate portion may define a cross-sectional width that tapers from the head portion to the base portion. The collar may have an inner surface defining a passage. A tubing may be stretched over the outer surface of the body with a proximal end portion of the tubing stretched over at least a portion of the outer surface of the body at the intermediate portion. The inner surface of the collar may be sleeved over a portion of the outer surface of the tubing and coupled to the collar such that the proximal end portion of the tubing is sandwiched and compressed between the body and the collar.
F16L 33/34 - Arrangements for connecting hoses to rigid membersRigid hose-connectors, i.e. single members engaging both hoses with bonding obtained by vulcanisation, gluing, melting, or the like
A61M 39/12 - Tube connectors or tube couplings for joining a flexible tube to a rigid attachment
F16L 11/06 - Hoses, i.e. flexible pipes made of rubber or flexible plastics with homogeneous wall
F16L 33/207 - Undivided rings, sleeves, or like members contracted on the hose or expanded inside the hose by means of toolsArrangements using such members only a sleeve being contracted on the hose
F16L 33/22 - Arrangements for connecting hoses to rigid membersRigid hose-connectors, i.e. single members engaging both hoses with means not mentioned in the preceding groups for gripping the hose between inner and outer parts
F16L 33/28 - Arrangements for connecting hoses to rigid membersRigid hose-connectors, i.e. single members engaging both hoses for hoses with one end terminating in a radial flange or collar
F16L 47/04 - Connecting arrangements or other fittings specially adapted to be made of plastics or to be used with pipes made of plastics with a swivel nut or collar engaging the pipe
62.
Particle Analyzers Having Scintillation Counters, And Methods of Use Thereof
Particle analyzers having scintillation counters are provided. Particle analyzers of interest include a flow cell for transporting particles in a flow stream, a light source for irradiating a particle in the flow stream at an interrogation point, a particle-modulated light detector for detecting light from the interrogation point, and a scintillation counter for assessing particle radioactivity. In embodiments, the scintillation counter is positioned within the flow cell and configured generate particle radioactivity data that may be associated with a given particle in a plurality of particles. Methods and non-transitory computer readable storage media for practicing the invention are also provided.
G01N 15/01 - Investigating characteristics of particlesInvestigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
A syringe body having a housing and a cannula assembly. The housing includes a proximal end, a distal end, and a sidewall extending between the proximal and distal end, the sidewall defining a chamber adapted to receive a medicament, and a fitting extending from the distal end of the housing and comprising an open proximal end, an open distal end, and a sidewall extending therebetween, an interior surface of the sidewall defining a passageway. The cannula assembly includes a hub and a cannula inserted in the passageway, and the hub is sized and shaped to substantially fill the passageway of the fitting. Also, a syringe including the syringe body, a plunger comprising a plunger rod, and a stopper attached to a distal end of the plunger rod and moveably received in the chamber of the housing of the syringe body.
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
64.
Holding Device for Medical Containers With Reinforcing Ribs for Increasing Stiffness and Reducing Deflection
A holding device configured to support medical containers includes a supporting plate having an upper surface, a lower surface, and a plurality of openings through the supporting plate configured to receive the medical containers. The holding device also includes a plurality of chimneys protruding from the upper surface and/or the lower surface of the supporting plate enclosing the openings, such that the plurality of chimneys guide insertion of the medical containers into the plurality of openings: and a plurality of reinforcing ribs protruding from the supporting plate extending between the plurality of chimneys. The plurality of reinforcing ribs include a first end portion extending radially from a first chimney of the plurality of chimneys and a second end portion extending radially from an adjacent second chimney of the plurality of chimneys.
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
65.
Tub for the Packaging of a Plurality of Nests of Plunger Stoppers With Guiding Features Ensuring a Reliable Location of the Nests Within the Tub
A nest and tub arrangement for the storage of medical device components including a tub having a plurality of guide elements extending from at least one surface of the tub and into the interior of the tub, and at least one nest having a plurality of receptacles for the storage of a plurality of medical device components therein. The at least one nest is sized and configured for placement within the tub such that the plurality of guide elements align and removably retain the at least one nest within the tub.
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
B65D 25/10 - Devices to locate articles in containers
66.
REMOTE SCANNING AND VALIDATING OF CLINICAL ORDER DEVICE CONFIGURATIONS
A system for scanning and validating clinical order device configurations is disclosed. A test instance of an infusion device is created based on a request, and an automated programming command is transmitted to the test instance. The automated programming command includes validation information for validating clinical order data, and a programming response is generated by the test instance based on the automated programming command, and provided for storage in a records system. In some implementations, the response includes an image, or reference to the image, of a graphical user interface that would be presented by the infusion device configured according to the validation information.
G16H 70/40 - ICT specially adapted for the handling or processing of medical references relating to drugs, e.g. their side effects or intended usage
G06V 10/75 - Organisation of the matching processes, e.g. simultaneous or sequential comparisons of image or video featuresCoarse-fine approaches, e.g. multi-scale approachesImage or video pattern matchingProximity measures in feature spaces using context analysisSelection of dictionaries
G06V 10/94 - Hardware or software architectures specially adapted for image or video understanding
G06V 10/98 - Detection or correction of errors, e.g. by rescanning the pattern or by human interventionEvaluation of the quality of the acquired patterns
G06V 30/12 - Detection or correction of errors, e.g. by rescanning the pattern
G06V 30/30 - Character recognition based on the type of data
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
67.
PACKAGE FOR MEDICAL DEVICE AND PACKAGED MEDICAL DEVICES
Packages comprising a pouch comprising a transparent multilayer laminate film comprising four edges including a first edge consisting essentially of a fold providing two plies of the multilayer laminate film at a second edge, a third edge and a fourth edge, each of the first edge, the second edge and the third edge comprising a seal between the plies, the transparent multilayer laminate film comprising a first layer comprising a biaxially oriented nylon, a transparent barrier layer that blocks oxygen and water vapor, and a sealing layer. The pouch may be impermeable to a sterilization gas such as ethylene oxide, vaporized hydrogen peroxide, or nitrogen dioxide. Also disclosed is a packaged medical device comprising the pouch and a medical device such as a syringe pre-filled with saline solution inside the pouch.
B32B 27/08 - Layered products essentially comprising synthetic resin as the main or only constituent of a layer next to another layer of a specific substance of synthetic resin of a different kind
Multiple lumen intravenous tubing systems can include multi-lumen tubing that can be coupled with a manifold, where the multi-lumen tubing includes multiple lumens extending within the tubing and which are fluidly coupled with counterpart fluid flow paths of the manifold when the multi-lumen tubing is connected to an outlet of the manifold, and where the manifold includes more than one inlet and an outlet with each inlet fluidly coupled to a respective fluid flow paths that can be fluidically separated from the other fluid flow paths of the manifold to permit directing a first fluid from through the manifold and multi-lumen tubing, and a second fluid through the manifold and multi-lumen tubing, without the first and second fluids intersecting.
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Maintaining a registry which allows healthcare providers to enter, track and/or report information relating to the outcomes of patients treated with medical devices
70.
SYSTEMS AND METHODS FOR COMPUTER-ASSISTED MEASUREMENT OF PULMONARY CAPILLARY WEDGE PRESSURE
Systems and methods for computer-assisted analysis of pulmonary capillary wedge pressure (PCWP) measurement acquisition in an individual are provided. Various systems and methods measure a wedge pressure via a pulmonary catheter and determine the quality of the wedge pressure measurement. In some instances, systems and methods utilize a trained computational model to assess PCWP quality. Systems and methods are also directed to determining transitions between a wedge and non-wedge positions, which may utilize fuzzy logic to identify such transitions based on a one or more hemodynamic features.
Non-parametric transforms such as t-distributed stochastic neighbor embedding (tSNE) are used to analyze multi-parametric data such as data derived from flow cytometry or other particle analysis systems and methods. These transforms may be included for dimensionality reduction and identification of subpopulations (e.g., gating). By nature, non-parametric transforms cannot transform new observations without training a new transformation based on the entire dataset including the new observations. The features described parameterize non-parametric transforms using a neural network thereby allowing a small training dataset to be transformed using non-parametric techniques. The training dataset may then be used to generate an accurate parametric model for assessing additional events in a manner consistent with the initial events.
G01N 15/01 - Investigating characteristics of particlesInvestigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
G01N 15/14 - Optical investigation techniques, e.g. flow cytometry
G01N 15/1404 - Handling flow, e.g. hydrodynamic focusing
In one aspect, a method of sorting cells in a flow cytometry system is disclosed, which includes illuminating a cell with radiation having at least two optical frequencies shifted from one another by a radiofrequency to elicit fluorescent radiation from the cell, detecting the fluorescent radiation to generate temporal fluorescence data, and processing the temporal fluorescence data to arrive at a sorting decision regarding the cell without generating an image (i.e., a pixel-by-pixel image) of the cell based on the fluorescence data. In other words, while the fluorescence data can contain image data that would allow generating a pixel-by-pixel fluorescence intensity map, the method arrives at the sorting decision without generating such a map. In some cases, the sorting decision can be made with a latency less than about 100 microseconds. In some embodiments, the above method of sorting cells can have a sub-cellular resolution, e.g., the sorting decision can be based on characteristics of a component of the cell. In some embodiments in which more than two frequency-shifted optical frequencies are employed, a single radiofrequency shift is employed to separate the optical frequencies while in other such embodiments a plurality of different radiofrequency shifts are employed.
A method may include reading, with a radio-frequency identification (RFID) reader, from a plurality of RFID tags on a plurality of medical devices in a production line, a plurality of identifiers associated with the plurality of medical devices, the plurality of medical devices in the production line being individually moved adjacent to an antenna of the RFID reader by a conveyor. For each identifier of the plurality of identifiers, at least one processor may determine whether that identifier is included in a list of expected identifiers, and in response to determining that that identifier is not included in the list of expected identifiers, control the conveyor to remove a medical device of the plurality of medical devices associated with that identifier from the production line.
G05B 19/418 - Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control [DNC], flexible manufacturing systems [FMS], integrated manufacturing systems [IMS] or computer integrated manufacturing [CIM]
G06Q 10/087 - Inventory or stock management, e.g. order filling, procurement or balancing against orders
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
Disclosed herein include systems, methods, compositions, and kits for 5′-based gene expression profiling. Some embodiments provide synthetic particles (e.g., beads) associated with a first plurality of oligonucleotide barcodes and a second plurality of oligonucleotide barcodes. In some embodiments, nucleic acid targets (e.g., mRNAs) are initially barcoded on the 3′ end with the first plurality of oligonucleotide barcodes and subsequently barcoded on the 5′ end following a template switching reaction and intermolecular hybridization with the first plurality of oligonucleotide barcodes and extension. Immune repertoire profiling methods are also provided in some embodiments.
A system includes a hardware unit that stores signal distortion detection code. The code causes the system to execute steps of a method for evaluating the fit and placement of a hemodynamic sensor. The method includes obtaining hemodynamic data from the hemodynamic sensor and determining an arterial pressure waveform based on the hemodynamic data. A distortion score is determined based on one or more features extracted from the arterial pressure waveform and a weighting module. The method includes selectively invoking a sensory alarm based on a comparison of the distortion score to a predetermined criterion or predetermined criteria.
In one aspect, a system for performing flow cytometry is disclosed, which comprises a laser for generating laser radiation for illuminating a sample, at least one detector for detecting at least a portion of a radiation emanating from the sample in response to said illumination so as to generate a temporal signal corresponding to said detected radiation, and an analysis module for receiving said temporal signal and performing a statistical analysis of said signal based on a forward model to reconstruct an image of said sample.
G01N 15/1433 - Signal processing using image recognition
G01N 15/01 - Investigating characteristics of particlesInvestigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
Compositions, methods and kits are disclosed for high-sensitivity single molecule digital counting by the stochastic labeling of a collection of identical molecules by attachment of a diverse set of labels. Each copy of a molecule randomly chooses from a non-depleting reservoir of diverse labels. Detection may be by a variety of methods including hybridization based or sequencing. Molecules that would otherwise be identical in information content can be labeled to create a separately detectable product that is unique or approximately unique in a collection. This stochastic transformation relaxes the problem of counting molecules from one of locating and identifying identical molecules to a series of binary digital questions detecting whether preprogrammed labels are present. The methods may be used, for example, to estimate the number of separate molecules of a given type or types within a sample.
Disclosed herein include methods, compositions, and kits for use in detecting a target nucleic acid sequence in a sample. The method can comprise the use of a lysis buffer comprising a lytic agent and/or a reducing agent for treating a sample and detecting the presence of a target nucleic acid sequence. In some embodiments, the method comprises contacting a reagent composition comprising amplification agents and one or more protectants (e.g., cyclodextrin compounds) capable of sequestering lytic agents with the treated sample to generate an amplification reaction mixture, for example under isothermal conditions, for detecting.
C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
The subject matter disclosed herein provides methods for distributing notifications to a user. The method can include receiving data encapsulating notifications from a device connected to a network that provide information relating to the device's status. The device can provide a health related treatment. The method can associate each notification with one or more notification categories relating to a function performed by the device or a location of the device. A table of users having one or more subscriptions to these notification categories can be accessed. The subscriptions can be automatically assigned to users based on the users' role. A user can be identified from the table to distribute the one or more notifications to. The user can have a subscription that matches a notification category of the received notifications, and data comprising the notifications can be distributed to the user. Related apparatus, systems, techniques, and articles are also described.
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G06F 3/0482 - Interaction with lists of selectable items, e.g. menus
G06Q 30/02 - MarketingPrice estimation or determinationFundraising
G06Q 50/22 - Social work or social welfare, e.g. community support activities or counselling services
G16H 15/00 - ICT specially adapted for medical reports, e.g. generation or transmission thereof
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A blood draw device for use with a catheter assembly is provided that includes a plurality of nestable barrels actuatable between an expanded state and a compressed state and a coupling device the mates the nestable barrels to the catheter assembly. The nestable barrels includes an inner barrel, intermediate barrel, and outer barrel. The inner barrel is configured to advance distally into the intermediate barrel and the outer barrel to nest the inner barrel therein, while both the intermediate barrel and inner barrel are configured to nest within the outer barrel, so as to put the plurality of nestable barrels into the compressed state. A blood draw tube is positioned within the nestable barrels and is movable from a first position where its distal end is disposed within the nestable barrels to a second position where its distal end is advanced into or through the catheter assembly.
Provided herein is a system for detecting needle shield piercing in RFID-tagged medical injection devices. The system includes a conveyor system configured to convey the injection devices along a conveying path, a RFID coupling element positioned at a reading location along the conveying path, a RFID reader configured to perform a singulated reading of the RFID tag of each injection device upon passing the RFID coupling element, and a processor coupled to a memory and configured to record, for each RFID tag read by the RFID reader, a carrier power of a signal transmitted from the RFID coupling element to the RFID tag needed to generate a backscattered signal response from the RFID tag, compare the carrier power to a specified reference carrier power threshold and, if the recorded carrier power is greater than the reference carrier power threshold, identify the respective injection device as having a pierced needle shield.
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
A61M 5/50 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
82.
Methods and systems for determining an ideal detector gain
Methods of determining an ideal gain for a detector in a light detection system of a flow cytometer are provided. Methods of interest include irradiating a flow stream with light from a light source, incrementally increasing the gain of the detector such that the detector collects light from the flow stream at each of a plurality of successively increasing gains, obtaining a baseline noise level from the detector at each gain in the plurality of successively increasing gains, calculating a limit of detection (LoD) for each gain in the plurality of successively increasing gains, and assessing the calculated LoDs to determine the ideal gain. Systems and computer readable storage media for practicing the invention are also provided.
A fluid applicator (100) with precise volume dispensing control for dispensing fluids such as a disinfectant in a controlled manner that utilizes a pumping device (180) at least partially inserted into a housing (110) having an applicator sponge (122).
Devices, systems, and methods convert linear displacement of expanding and contracting flexible reservoir into rotational displacement which can be correlated to volume of reservoir through numerical measurements. Sensor can comprises one or more components the rotational displacement of which can be correlated to the volume of the flexible reservoir through numerical measurements. Rotation can be converted into digital data indicative of measurement of volume of flexible reservoir. Medical devices for administering liquid drug therapy comprising a flexible reservoir can implement such devices, systems, or methodology.
Post induction hypotension (PIH) may be associated with an increase of morbidity and mortality. As PIH is caused by different (pharmacological) mechanisms compared to intra operative hypotension (IOH), using any of the various definitions for IOH is inadequate. Accordingly, the present application describes a more comprehensive method to assess clinically relevant PIH (defined as “crasher”) based on visual blood pressure patterns and an automated classification model able to classify these types of patients.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/021 - Measuring pressure in heart or blood vessels
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
87.
Device and System for Transporting Medical Devices
A device for supporting a plurality of medical containers includes a plate having upper and lower surfaces and a sidewall defining a plate perimeter and extending between the upper and lower surface. The sidewall includes four edges intersecting at corners. A longitudinal axis of the plate extends perpendicular to the upper surface. The plate defines a plurality of openings extending through the plate from the upper to lower surface. Each opening is configured to retain a medical container therein. The plate is dimensioned to be disposed in a packaging such that a distance measured between opposing edges of the sidewall is less than a distance measured between opposing sidewalls of an interior surface of the packaging. The device further includes at least two positioning elements coupled at a first end thereof to the plate. Each positioning element has a second end detached from the plate.
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A catheter insertion device includes a housing with a base, a catheter, an insertion needle and an actuator. The device includes at least one spring that is actuated by the actuator to move the insertion needle and catheter to an extended position. In one embodiment, the spring can also retract the insertion needle automatically when the catheter is in the extended position. The spring can be operatively connect to a sleeve that rotates to move the insertion needle and catheter to the extended position and then retract the insertion needle. In another embodiment, the device includes a first spring to move the insertion needle and catheter to the extended position and a second spring to retract the insertion needle.
A catheter insertion device including: a housing defining a first channel; a septum defining a second channel and an opening extending from the second channel; and a catheter at least partially positioned within the opening of the septum. The septum is movable relative to the housing between a first position and a second position. In the first position, the septum is spaced apart from the first channel of the housing, and in the second position, the septum is positioned adjacent the first channel to align the second channel with the first channel, permitting fluid flow from the first channel to the second channel.
An injection mechanism for a fluid delivery device has a manifold configured to cooperate with a button for slidable engagement within a frame. The manifold and frame have openings for selective fluidic connection to other components related to the fluid delivery device such as a monodirectional pump, a reservoir and a primary container for storing fluid used to full the reservoir. Some manifold openings have a fluid channel connected therebetween. At least one manifold opening has a fluid channel connected between it and a fluid channel of a needle or catheter that is inserted into a patient. The manifold openings are arranged along the manifold such that a subset of the manifold openings are aligned with the frame openings when the button is in a first position, and a different subset of the manifold openings are aligned with the frame openings when the button is in a second position.
Disclosed herein are various pump systems for a portable blood pressure monitoring system. One particular pump system includes: a pump including an inlet and an outlet; inlet pressure chambers connected to the inlet, where the inlet pressure chambers are connected in series to such that a last inlet pressure chamber is connected to the inlet of the pump and a beginning inlet pressure chamber is connected to outside air; outlet pressure chambers connected to the outlet, where each of the outlet pressure chambers are connected in series such that a beginning outlet pressure chamber is connected to the outlet of the pump and a last outlet pressure chamber is connected to a port.
A61B 5/0225 - Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skinOphthaldynamometers the pressure being controlled by electric signals, e.g. derived from Korotkoff sounds
92.
SYSTEMS AND METHODS FOR ASSESSMENT OF BLOOD OXYGENATION
Systems and methods for assessing arterial oxygen saturation concurrent with performing continuous blood pressure monitoring via the volume clamp method are described. Generally, a cuff system can be configured to fit onto a body appendage. The cuff system can comprise a pressurizable bladder and a photoplethysmograph. Methods can perform arterial oxygen saturation while the artery of the body appendage is in the unloaded state. Minor fluctuations of plethysmogram signal can be utilized along with a computed calibration factor to compute arterial oxygen saturation.
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61B 5/021 - Measuring pressure in heart or blood vessels
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A system for monitoring arterial pressure of a patient determines a score that is predictive of responsiveness of the patient to a therapy. Sensed hemodynamic data representative of an arterial pressure waveform of the patient are received by a hemodynamic monitor. Magnitude data and trend data are derived from the hemodynamic data. The score that is predictive of the responsiveness of the patient to the therapy is determined based on the magnitude data and the trend data of the hemodynamic parameter. A representation of the score is output.
A61B 5/029 - Measuring blood output from the heart, e.g. minute volume
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
94.
MANUAL CATHETER INSERTION DEVICE FOR MEDICAMENT DELIVERY DEVICE
A catheter insertion device including a housing having a cam member, a needle hub having an introducer needle, and a catheter hub having a catheter. The catheter hub has a fluid opening fluidly communicable with the catheter. The needle hub or the catheter hub includes at least one operation pin, and the needle hub and the catheter hub move together from initial to extended positions. The device includes an insertion unit to move the needle hub and the catheter hub, and at least one spring. During movement toward the extended position, the operation pin engages the cam member to rotate the needle hub or the catheter hub, freeing relative securement of the needle hub and the catheter hub, enabling the at least one spring to withdraw the introducer needle from the catheter, establishing fluid communication between the fluid opening and a distal end of the catheter.
FLUID DELIVERY DEVICE MANIFOLD SWITCHABLE FROM FILL POSITION FOR FILLING RESERVOIR FROM PRIMARY CONTAINER TO INJECTION POSITION TO INJECT FLUID FROM RESERVOIR
A manifold having a mobile part and a fixed part is provided for convenient configuration of a fluid delivery device for filling or for injection using a monodirectional pump. Fixed part ports are fluidically connected to reservoir, pump mechanism, and injection outlet (e.g., catheter) of the fluid delivery device. Mobile part ports are selectively aligned with a primary container used for filling and fixed part ports, depending movement of the mobile part relative to the fixed part for a filling position or an injection position of the manifold. Different manifolds are provided that use various connections between the mobile part and the primary container (e.g., a vial adapter, a syringe) to allow for use of different types of primary containers for filling and to impart the selected movement of the mobile part relative to the fixed part for the desired position of the manifold for storage, filling or injection.
A delivery device is provided with an insertion device having a retraction spring configuration for automatic insertion needle retraction. A button of the insertion device is used to insert the insertion needle and catheter, and once the insertion needle are fully inserted, a rotating engagement releases the needle hub where the springs automatically retract the insertion needle. A catheter assembly includes a catheter hub, a septum and a catheter. The catheter hub has a fluid passage separate from the insertion needle to supply a fluid to the catheter. The fluid passage can extend through a distal end of the septum, through a side portion of the catheter hub and septum, or through a side portion of the catheter hub directly to a fluid chamber formed between the septum and a distal end of the catheter hub.
Systems and methods identify respiration signals in a patient, which can be important for monitoring respiratory health. A respiration signal can be extracted based on data within a physiological waveform, such as a blood pressure waveform, a blood flow waveform, an electrocardiogram, or a plethysmogram. The physiological waveform can be filtered to identify and extract the respiration signal, which can be utilized to construct a capnogram waveform. A respiration rate can be calculated from the respiration signal or from the constructed capnogram waveform.
Luer retaining devices that provide increased retention between bearings and syringe tips are disclosed. A luer retaining device includes a male luer and a female luer. The male luer includes a syringe tip and the female luer includes a bearing that receives the syringe tip. The female luer includes at least one barb that extends from the bearing for engaging the syringe tip. The male luer and the female luer in fluid communication when the bearing receives the syringe tip.
Disclosed herein include systems, methods, compositions, and kits for detecting cellular component-binding reagents comprising a cellular component-binding reagent specific oligonucleotide having a unique identifier sequence for the cellular component-binding reagent. Provided herein include first detectable conjugates comprising a detectable moiety, or precursor thereof, and a unique identifier specific oligonucleotide having a sequence configured to bind a unique identifier sequence. Also provided herein are second detectable conjugates comprising a detectable moiety, or precursor thereof, and a shared oligonucleotide having a sequence configured to bind a shared sequence of the cellular component-binding reagent specific oligonucleotides.
