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Found results for
 patents
1.
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PROCESSES FOR THE PRODUCTION OF A LACTONE STATIN INTERMEDIATE BY ENZYMATIC OXIDATION
| Application Number |
IB2012056183 |
| Publication Number |
2013/068917 |
| Status |
In Force |
| Filing Date |
2012-11-06 |
| Publication Date |
2013-05-16 |
| Owner |
- DR. REDDY'S LABORATORIES LIMITED (India)
- DR REDDY'S LABORATORIES (EU) LIMITED (United Kingdom)
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| Inventor |
Anna, Fryszkowska
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Abstract
The present application relates to a process for the preparation of lactones by enzymatic oxidation of lactols. The lactones, produced thus may be useful for the synthesis of statins, including but not limited to, cerivastatin, pitavastatin, fluvastatin, pravastatin, atorvastatin, rosuvastatin etc. The present application also relates to a crystalline form of (4R,6S)-6-(chloromethyl)tetrahydro-2H-pyran-2,4-diol (2a).
IPC Classes ?
- C12P 17/02 - Oxygen as only ring hetero atoms
- C12P 17/16 - Preparation of heterocyclic carbon compounds with only O, N, S, Se, or Te as ring hetero atoms containing two or more hetero rings
- C12P 7/26 - Ketones
- C12P 7/02 - Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P 7/22 - Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
- C07D 309/00 - Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D 309/30 - Oxygen atoms, e.g. delta-lactones
- C07C 59/105 - Polyhydroxy carboxylic acids having five or more carbon atoms, e.g. aldonic acids
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2.
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PRODUCTION OF ENANTIOMERICALLY PURIFIED AMINO ACIDS
| Application Number |
IB2012000836 |
| Publication Number |
2012/140507 |
| Status |
In Force |
| Filing Date |
2012-04-10 |
| Publication Date |
2012-10-18 |
| Owner |
- DR. REDDY'S LABORATORIES (EU) LIMITED (United Kingdom)
- THE UNIVERSITY OF EDINBURGH (United Kingdom)
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| Inventor |
- Baxter, Scott
- Campopiano, Dominic
- Holt-Tiffin, Karen, Elizabeth
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Abstract
The present application relates to a mutated Amycoiatopsis sp. TS-1-60 NAAAR that shows improved activity of the enzyme compared with the wild type Amycoiatopsis sp. TS-1-60 NAAAR. The mutated NAAAR is almost five times more active than its wiid type counterpart. The present application also relates to the use of mutated Amycoiatopsis sp. TS-1 -60 NAAAR in the production of enantiomerically pure amino acid from its N-acyl derivative via dynamic kinetic resolution method.
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