Goods & Services

Laboratory, scientific, optical, and electrical research apparatus and instruments, namely, digital microfluidic platforms comprised primarily of computer hardware and also including recorded computer software for automating sample preparation, droplet manipulation, and data analysis in laboratory workflows, microchannel wafers, and sensor chips for use in the fields of laboratory, scientific, optical and electrical research; Digital microfluidic platforms comprised primarily of computer hardware and also including recorded computer software for automating sample preparation, droplet manipulation, and data analysis in laboratory workflows, microchannel wafers, and sensor chips for use in the fields of laboratory, scientific, optical and electrical research; Digital microfluidic platforms comprised primarily of computer hardware and also including recorded computer software for use in automating sample preparation, droplet manipulation, and data analysis in laboratory workflows, microchannel wafers, and sensor chips for use in the fields of laboratory, scientific, optical and electrical research; Digital microfluidic platforms comprised primarily of computer hardware and also including recorded computer software for biological, genetic, chemical, medical, and scientific research and analysis, power controllers, and sensor chips for laboratory, scientific, optical and electrical research; Digital microfluidic platforms comprised primarily of computer hardware and also including recorded computer software for sample preparation, manipulation, and analysis in chemical and biochemical workflows for laboratory, scientific, optical and electrical research; Digital microfluidic platforms comprised primarily of computer hardware and also including recorded computer software for testing and measuring an attribute in assays for use in the fields of laboratory, scientific, optical and electrical research; Digital microfluidic platforms comprised primarily of computer hardware and also including recorded computer software for single-cell and bulk-sample analyses for identifying, isolating, capturing, sorting, imaging, counting, and analyzing cells and tissue for use in the fields of laboratory, scientific, optical and electrical research; Scientific apparatus and instruments, namely, electronic analyzers for testing and analyzing chemical and biological substances for the presence, absence, or quantity of biomarkers, proteins, nucleic acids, metabolites, chemical contaminants and biological contaminants; Scientific apparatus and instruments for creating, analyzing, and manipulating droplets and micro-droplets for the presence, absence, or quantity of biomarkers, proteins, nucleic acids, metabolites, chemical contaminants and biological contaminants; Kits comprising peptide substrates for preparing samples for chemical analysis, biochemical analysis, imaging microfluidic analysis, and digital microfluidic analysis; Data processing equipment for use with apparatus and instruments for creating, analysing and manipulating droplets and micro-droplets; Downloadable software for chemical and biochemical analysis in the field of scientific imaging and microfluidics; Downloadable computer software and embedded firmware for configuring, operating, and analyzing data from digital microfluidic platforms used in chemical, biochemical, and medical assays; Scientific research platform device comprised primarily of computer hardware and also including recorded software for single-cell and bulk-sample analyses for identifying, isolating, capturing, sorting, imaging, counting, and analyzing cells and tissue for use in the fields of laboratory, scientific, optical and electrical research; Scientific research platform device comprised primarily of computer hardware and recorded software for use in automating sample preparation, droplet manipulation, and data analysis in laboratory workflows; Downloadable scientific and medical data for use in chemical analysis, biochemical analysis and microfluidic analysis; Electronic circuit boards for use as controllers for digital microfluidic platform devices; Scientific laboratory research instruments for use with digital microfluidic applications in the field of medical imaging; Microscopes for use with digital microfluidic chips; Integrated digital microfluidic platforms comprised primarily of computer hardware and also including recorded computer software for sample preparation for use with external analytical instruments, namely, instruments for mass spectrometry, instruments for fluorescence spectroscopy, electrochemical sensors, and nucleic acid sequencing instruments ; Remote controls for digital microfluidic platform devices and sensor chips for digital microfluidic platform devices for scientific use; Automated liquid handling systems comprised primarily of computer hardware, electronic controllers, sensor chips, and recorded computer software for automating sample preparation, droplet manipulation, and fluid dispensing in digital microfluidic workflows, and laboratory consumables, namely, pipette tips for digital microfluidic workflows; Automated liquid handling systems comprised primarily of computer hardware, electronic controllers, sensor chips, and recorded computer software for automating sample preparation, droplet manipulation, and fluid dispensing in digital microfluidic workflows; Computer hardware and downloadable computer software for controlling automated liquid handling systems; Digital microfluidic platforms comprised primarily of computer hardware and also including recorded computer software for use in agricultural testing, environmental testing and food testing for laboratory, scientific, optical and electrical research Medical devices, namely, digital microfluidic platforms for in vitro diagnostic testing of patient samples for the diagnosis and monitoring of hematologic disorders, coagulation disorders, infectious diseases, metabolic disorders, cardiovascular disorders, inflammatory disorders, immunologic disorders, genetic disorders, and for blood transfusion compatibility testing, namely, blood group typing; Medical devices, namely, digital microfluidic platforms for sample preparation and analysis in medical and clinical research and for chemical assays, biochemical assays, and clinical diagnostics in laboratory settings for the diagnosis and monitoring of hematologic disorders, coagulation disorders, infectious diseases, metabolic disorders, cardiovascular disorders, inflammatory disorders, immunologic disorders, genetic disorders, and for blood transfusion compatibility testing, namely, blood group typing; Digital microfluidic platforms for research use in medical and life sciences applications, for cellular and molecular analysis in research and laboratory settings, and for point-of-care diagnostic testing for the diagnosis and monitoring of hematologic disorders, coagulation disorders, infectious diseases, metabolic disorders, cardiovascular disorders, inflammatory disorders, immunologic disorders, genetic disorders, and for blood transfusion compatibility testing, namely, blood group typing; AI-assisted digital microfluidic platforms for automated biomarker detection for the diagnosis and monitoring of hematologic disorders, coagulation disorders, infectious diseases, metabolic disorders, cardiovascular disorders, inflammatory disorders, immunologic disorders, genetic disorders, and for blood transfusion compatibility testing, namely, blood group typing; Apparatus and instruments for droplet chemical and biochemical analysis for medical diagnostic purposes; Laboratory-based instruments and consumables in the nature of digital microfluidic medical analyzers and disposable medical diagnostic cartridges for medical sample preparation and analysis, namely, biomarker detection, cytokine profiling, nucleic acid analysis, and therapeutic drug monitoring for the diagnosis and monitoring of hematologic disorders, coagulation disorders, infectious diseases, metabolic disorders, cardiovascular disorders, inflammatory disorders, immunologic disorders, genetic disorders, and for blood transfusion compatibility testing, namely, blood group typing; Digital microfluidic chips for use in medical applications, namely, detecting biomarkers, performing immunoassays, and point-of-care diagnostic tests for the diagnosis and monitoring of hematologic disorders, coagulation disorders, infectious diseases, metabolic disorders, cardiovascular disorders, inflammatory disorders, immunologic disorders, genetic disorders, and for blood transfusion compatibility testing, namely, blood group typing

Goods & Services

Laboratory, scientific, optical, and electrical research apparatus and instruments, namely, digital microfluidic platforms; digital microfluidic platforms comprised of computer hardware and software for use in the fields of laboratory, scientific, optical and electrical research; digital microfluidic platforms comprised of computer hardware and software for use in automating sample preparation, droplet manipulation, and data analysis in laboratory workflows; digital microfluidic controllers, systems, and chips for biological, genetic, chemical and scientific and medical research as well as scientific analysis; apparatus for medical research analysis, namely, nucleic acid amplification, protein detection, drug discovery, point-of-care diagnostics, and high-throughput screening; digital microfluidic platforms for sample preparation, manipulation, and analysis in chemical workflows; digital microfluidic platforms for sample preparation, manipulation, and analysis in chemical workflows, namely, for the synthesis of small molecules, peptides, DNA/RNA, nanoparticles, and biochemical reagents; digital microfluidic platforms for chemical workflows, namely, the detection and analysis of small molecules, metabolites, environmental contaminants, pharmaceutical compounds, and industrial chemicals; digital microfluidic platforms for sample preparation, manipulation, and analysis in biochemical workflows; digital microfluidic platforms for sample preparation, manipulation, and analysis in biochemical workflows, namely, for automating complex sample processing, including multi-step reactions and separations; digital microfluidic platforms for sample preparation, manipulation, and analysis in biochemical workflows, namely, for detecting biomarkers, proteins, nucleic acids, small molecules, and cell viability; digital microfluidic platforms for sample preparation, manipulation, and analysis in biochemical workflows, namely, for performing immunoassays, enzyme kinetics, and detecting genetic markers; digital microfluidic platforms for testing and measuring an attribute in assays; digital microfluidic platforms for testing and measuring an attribute in assays, namely, for measuring colorimetric changes including absorbance and transmittance and optical density, fluorescence intensity and emission spectra, luminescence, electrochemical properties including impedance and conductivity and redox potential, refractive index shifts, temperature and thermal properties, droplet volume and morphology, surface tension and contact angle, viscosity and rheological properties, magnetic properties, pH and ionic strength changes, turbidity and particle size distribution, optical scattering and light diffraction, dielectric and capacitive properties; digital microfluidic platforms for testing and measuring an attribute in assays, namely, droplet digital PCR, digital ELISA, and single-molecule detection assays; digital microfluidic platforms for single-cell and bulk-sample analyses for identifying, isolating, capturing, sorting, imaging, counting, and analyzing cells and tissue; digital microfluidic platforms for single-cell and bulk-sample analyses for identifying, isolating, capturing, sorting, imaging, counting, and analyzing cells and tissue, namely, single-cell and high-throughput analyses; apparatus and instruments for chemical and biological analysis; scientific apparatus and instruments for creating, analysing and manipulating droplets and micro-droplets; kits for preparing samples for chemical and biochemical analysis, imaging and digital microfluidic analysis; data processing equipment for apparatus and instruments for creating, analysing and manipulating droplets and micro-droplets; downloadable software in the field of chemical and biochemical analysis, imaging and microfluidics; downloadable computer software and embedded firmware for configuring, operating, and analyzing data from digital microfluidic platforms used in chemical, biochemical, and medical assays; scientific research platform comprised of computer hardware and software for use in the fields of laboratory, scientific, optical and electrical research; scientific research platform comprised of computer hardware and software for use in automating sample preparation, droplet manipulation, and data analysis in laboratory workflows; downloadable data and information to enable chemical and biochemical analysis and microfluidic analysis; electronic control boards, components, and embedded scientific systems for digital microfluidic applications; scientific imaging systems designed for digital microfluidic applications; microscopes for use with digital microfluidic chips; integrated digital microfluidic platforms for coupling with external analytical instruments, namely, mass spectrometry, fluorescence spectroscopy, electrochemical sensors, and sequencing systems; digital microfluidic platforms for multi-omics applications, namely, proteomics, genomics, and metabolomics; digital microfluidic controllers, digital microfluidic scientific apparatus, and chips; automated scientific apparatus for liquid handling and digital microfluidic workflows; digital microfluidic chips, cartridges, and apparatus for laboratory and scientific use; digital microfluidic chips, cartridges, and consumables for laboratory and scientific use, namely, disposable and reusable platforms for preparing, manipulating, and analyzing chemical, biochemical, and biological samples; laboratory consumables, namely, digital microfluidic chips used for droplet-based sample preparation, isolation, sorting, and detection of biological and chemical substances; automated liquid handling scientific apparatus; downloadable computer software and hardware for controlling automated liquid handling systems; digital microfluidic platforms for use in agricultural testing, environmental testing and food testing; digital microfluidic devices for use in environmental testing, namely, for detecting contaminants, toxins, and pathogens in water, soil, and food products; medical and clinical research apparatus, namely microfluidic platforms for sample preparation and analysis; digital microfluidic platforms for chemical assays, biochemical assays, and clinical diagnostics in laboratory settings for medical use; digital microfluidic platforms for research use in medical and life sciences applications; digital microfluidic platforms for cellular and molecular analysis in research and laboratory settings; digital microfluidic platforms for point-of-care diagnostic testing in hematology, oncology, infectious disease screening, and autoimmune disorder detection; laboratory AI-assisted digital microfluidic platforms for automated biomarker detection; laboratory instruments and apparatus for medical sample preparation, namely, for biomarker detection, cytokine profiling, nucleic acid analysis, and therapeutic drug monitoring for medical use; digital microfluidic chips for use in medical applications, namely, detecting biomarkers, performing immunoassays, and point-of-care diagnostic tests. Medical devices, namely, digital microfluidic platforms; apparatus and instruments for droplet chemical analysis for medical purposes; apparatus and instruments for droplet biochemical analysis for medical purposes; apparatus and instruments for droplet-based chemical analysis of patient samples for medical purposes, namely, immunoassays, molecular diagnostics, and cell screening; apparatus and instruments for droplet-based biochemical analysis of patient samples for medical purposes, namely, immunoassays, molecular diagnostics, and cell screening; apparatus for medical analysis.

Goods & Services

(1) Laboratory, scientific, optical, and electrical research apparatus and instruments, namely, digital microfluidic platforms; digital microfluidic platforms comprised of computer hardware and software for use in the fields of laboratory, scientific, optical and electrical research; digital microfluidic platforms comprised of computer hardware and software for use in automating sample preparation, droplet manipulation, and data analysis in laboratory workflows; digital microfluidic controllers, systems, and chips for biological, genetic, chemical, medical, and scientific research and analysis; digital microfluidic controllers, systems, and chips for biological, genetic, chemical, medical, and scientific research and analysis, namely, nucleic acid amplification, protein detection, drug discovery, point-of-care diagnostics, and high-throughput screening; digital microfluidic platforms for sample preparation, manipulation, and analysis in chemical workflows; digital microfluidic platforms for sample preparation, manipulation, and analysis in chemical workflows, namely, for the synthesis of small molecules, peptides, DNA/RNA, nanoparticles, and biochemical reagents; digital microfluidic platforms for chemical workflows, namely, the detection and analysis of small molecules, metabolites, environmental contaminants, pharmaceutical compounds, and industrial chemicals; digital microfluidic platforms for sample preparation, manipulation, and analysis in biochemical workflows; digital microfluidic platforms for sample preparation, manipulation, and analysis in biochemical workflows, namely, for automating complex sample processing, including multi-step reactions and separations; digital microfluidic platforms for sample preparation, manipulation, and analysis in biochemical workflows, namely, for detecting biomarkers, proteins, nucleic acids, small molecules, and cell viability; digital microfluidic platforms for sample preparation, manipulation, and analysis in biochemical workflows, namely, for performing immunoassays, enzyme kinetics, and detecting genetic markers; digital microfluidic platforms for testing and measuring an attribute in assays; digital microfluidic platforms for testing and measuring an attribute in assays, namely, for measuring colorimetric changes including absorbance and transmittance and optical density, fluorescence intensity and emission spectra, luminescence, electrochemical properties including impedance and conductivity and redox potential, refractive index shifts, temperature and thermal properties, droplet volume and morphology, surface tension and contact angle, viscosity and rheological properties, magnetic properties, pH and ionic strength changes, turbidity and particle size distribution, optical scattering and light diffraction, dielectric and capacitive properties; digital microfluidic platforms for testing and measuring an attribute in assays, namely, droplet digital PCR, digital ELISA, and single-molecule detection assays; digital microfluidic platforms for single-cell and bulk-sample analyses for identifying, isolating, capturing, sorting, imaging, counting, and analyzing cells and tissue; digital microfluidic platforms for single-cell and bulk-sample analyses for identifying, isolating, capturing, sorting, imaging, counting, and analyzing cells and tissue, namely, single-cell and high-throughput analyses; digital microfluidic sampleprocessing kits comprised of digital microfluidic chips, microfluidic cartridges, sample vials for laboratory use, laboratory microtubes, pipette tips, and reagent reservoirs sold together as a unit for preparing samples for chemical and biochemical analysis, imaging and digital microfluidic analysis; downloadable computer software and embedded firmware for configuring, operating, and analyzing data from digital microfluidic platforms used in chemical, biochemical, and medical assays; scientific research platform comprised of computer hardware and downloadable software for configuring, operating, and analyzing data from digital microfluidic platforms for use in the fields of laboratory, scientific, optical and electrical research; scientific research platform comprised of computer hardware and software for use in automating microfluidic sample dispensing, merging and splitting, droplet manipulation, and data analysis in laboratory workflows; downloadable data and information to enable chemical and biochemical analysis and microfluidic analysis; electronic control boards, and embedded control systems for controlling and operating digital microfluidic platforms; scientific imaging systems consisting of optical sensors, cameras, and illumination modules designed for analyzing droplets and sample reactions in digital microfluidic applications; microscopes for use with digital microfluidic chips; integrated digital microfluidic platforms for coupling with external analytical instruments, namely, mass spectrometry, fluorescence spectroscopy, electrochemical sensors, and sequencing systems; digital microfluidic platforms for multi-omics applications, namely, proteomics, genomics, and metabolomics; digital microfluidic controllers, systems, and chips; automated liquid handling systems and consumables, namely, microfluidic cartridges, reagent reservoirs, and disposable microfluidic chips for digital microfluidic workflows; digital microfluidic chips, cartridges, and consumables for laboratory and scientific use, namely, disposable and reusable platforms for preparing, manipulating, and analyzing chemical, biochemical, and biological samples; laboratory consumables, namely, digital microfluidic chips used for droplet-based sample preparation, isolation, sorting, and detection of biological and chemical substances; downloadable computer software and hardware for operating automated liquid handling equipment used to dispense, transfer, and process liquid samples in digital microfluidic workflows; digital microfluidic platforms for use in agricultural testing, environmental testing and food testing; digital microfluidic devices for use in environmental testing, namely, for detecting contaminants, toxins, and pathogens in water, soil, and food products; digital microfluidic platforms for research use in medical and life sciences applications; digital microfluidic platforms for cellular and molecular analysis in research and laboratory settings; digital microfluidic platforms for point-of-care diagnostic testing in hematology, oncology, infectious disease screening, and autoimmune disorder detection; AI-assisted digital microfluidic platforms for automated biomarker detection; laboratory-based instruments and consumables for medical sample preparation, namely, biomarker detection, cytokine profiling, nucleic acid analysis, and therapeutic drug monitoring; digital microfluidic chips for use in medical applications, namely, detecting biomarkers, performing immunoassays, and point-of-care diagnostic tests (2) Medical devices, namely, digital microfluidic platforms; medical devices, namely, digital microfluidic platforms for sample preparation and analysis in medical and clinical research; medical devices, namely, digital microfluidic platforms for chemical assays, biochemical assays, and clinical diagnostics in laboratory settings; apparatus and instruments for droplet chemical analysis for medical purposes; apparatus and instruments for droplet biochemical analysis for medical purposes; apparatus and instruments for dropletbased chemical analysis of patient samples for medical purposes, namely, immunoassays, molecular diagnostics, and cell screening; apparatus and instruments for droplet-based biochemical analysis of patient samples for medical purposes, namely, immunoassays, molecular diagnostics, and cell screening

Goods & Services

(1) Scientific instrument used for microfluidics research.

Abstract

The present disclosure discloses a multi-droplet sensing and actuation system, for use in a digital microfluidic chip operation wherein a linearly independent alternating current signal is applied to each discrete actuation electrode thus encoding the electrode's identity. The combined measured impedance signal from multiple channels is then processed to decode an impedance measurement for the volume between each discrete actuation electrode and its corresponding conductive counter electrode region, where the sensed impedance is inversely proportional to an amount of liquid within the volume.

IPC Classes  ?

• G01N 27/447 - Systems using electrophoresis
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• G01P 5/08 - Measuring speed of fluids, e.g. of air streamMeasuring speed of bodies relative to fluids, e.g. of ship, of aircraft by measuring variation of an electric variable directly affected by the flow, e.g. by using dynamo-electric effect
• G01F 22/00 - Methods or apparatus for measuring volume of fluids or fluent solid material, not otherwise provided for
• G01N 15/10 - Investigating individual particles

Abstract

The present disclosure discloses a multi-droplet sensing and actuation system, for use in a digital microfluidic chip operation wherein a linearly independent alternating current signal is applied to each discrete actuation electrode thus encoding the electrode's identity. The combined measured impedance signal from multiple channels is then processed to decode an impedance measurement for the volume between each discrete actuation electrode and its corresponding conductive counter electrode region, where the sensed impedance is inversely proportional to an amount of liquid within the volume.

IPC Classes  ?

• G01N 15/10 - Investigating individual particles
• B81B 7/02 - Microstructural systems containing distinct electrical or optical devices of particular relevance for their function, e.g. microelectro-mechanical systems [MEMS]
• G01F 22/00 - Methods or apparatus for measuring volume of fluids or fluent solid material, not otherwise provided for
• G01P 5/08 - Measuring speed of fluids, e.g. of air streamMeasuring speed of bodies relative to fluids, e.g. of ship, of aircraft by measuring variation of an electric variable directly affected by the flow, e.g. by using dynamo-electric effect