05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical
preparations for the prevention and treatment of allergies;
pharmaceutical preparations for the prevention and treatment
of autoimmune conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of blood conditions, diseases and disorders; pharmaceutical
preparations for the prevention and treatment of
cardiovascular diseases and disorders; pharmaceutical
preparations for the prevention and treatment of conditions,
diseases, and disorders of the central and peripheral
nervous system; pharmaceutical preparations for the
prevention and treatment of dermatological conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of endocrine conditions, diseases,
and disorders; pharmaceutical preparations for the
prevention and treatment of gastrointestinal conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of hepatic conditions, diseases,
and disorders; pharmaceutical preparations for the
prevention and treatment of immunological conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of infectious diseases;
pharmaceutical preparations for the prevention and treatment
of inflammatory conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of metabolic conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of muscular conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of neurological conditions, diseases, and disorders;
pharmaceutical preparations for the treatment of pain;
pharmaceutical preparations for the prevention and treatment
of psychiatric conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of respiratory and pulmonary conditions, diseases, and
disorders; pharmaceutical preparations for the prevention
and treatment of renal conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of urological conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical
preparations for the prevention and treatment of allergies;
pharmaceutical preparations for the prevention and treatment
of autoimmune conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of blood conditions, diseases and disorders; pharmaceutical
preparations for the prevention and treatment of
cardiovascular diseases and disorders; pharmaceutical
preparations for the prevention and treatment of conditions,
diseases, and disorders of the central and peripheral
nervous system; pharmaceutical preparations for the
prevention and treatment of dermatological conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of endocrine conditions, diseases,
and disorders; pharmaceutical preparations for the
prevention and treatment of gastrointestinal conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of hepatic conditions, diseases,
and disorders; pharmaceutical preparations for the
prevention and treatment of immunological conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of infectious diseases;
pharmaceutical preparations for the prevention and treatment
of inflammatory conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of metabolic conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of muscular conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of neurological conditions, diseases, and disorders;
pharmaceutical preparations for the treatment of pain;
pharmaceutical preparations for the prevention and treatment
of psychiatric conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of respiratory and pulmonary conditions, diseases, and
disorders; pharmaceutical preparations for the prevention
and treatment of renal conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of urological conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical
preparations for the prevention and treatment of allergies;
pharmaceutical preparations for the prevention and treatment
of autoimmune conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of blood conditions, diseases and disorders; pharmaceutical
preparations for the prevention and treatment of
cardiovascular diseases and disorders; pharmaceutical
preparations for the prevention and treatment of conditions,
diseases, and disorders of the central and peripheral
nervous system; pharmaceutical preparations for the
prevention and treatment of dermatological conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of endocrine conditions, diseases,
and disorders; pharmaceutical preparations for the
prevention and treatment of gastrointestinal conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of hepatic conditions, diseases,
and disorders; pharmaceutical preparations for the
prevention and treatment of immunological conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of infectious diseases;
pharmaceutical preparations for the prevention and treatment
of inflammatory conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of metabolic conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of muscular conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of neurological conditions, diseases, and disorders;
pharmaceutical preparations for the treatment of pain;
pharmaceutical preparations for the prevention and treatment
of psychiatric conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of respiratory and pulmonary conditions, diseases, and
disorders; pharmaceutical preparations for the prevention
and treatment of renal conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of urological conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of viral diseases.
The disclosure provides a topical gel formulation comprising 1-1.5 wt. % clindamycin phosphate, 2.5-3.5 wt. % benzoyl peroxide, and 0.1-0.2 wt. % adapalene, in combination with a gelling agent, a polyhydric alcohol, and water, useful in treating inflammatory skin conditions, including acne, together with methods of making and using the same.
A61K 31/7056 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
05 - Pharmaceutical, veterinary and sanitary products
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(1) Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
Described herein are methods for treating ulcerative colitis (UC) using amiselimod. The method of treatment includes dosing amiselimod at a larger initial dose as compared to the eventual maintenance dose.
The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical
preparations for the prevention and treatment of allergies;
pharmaceutical preparations for the prevention and treatment
of autoimmune conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of blood conditions, diseases and disorders; pharmaceutical
preparations for the prevention and treatment of
cardiovascular diseases and disorders; pharmaceutical
preparations for the prevention and treatment of conditions,
diseases, and disorders of the central and peripheral
nervous system; pharmaceutical preparations for the
prevention and treatment of dermatological conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of endocrine conditions, diseases,
and disorders; pharmaceutical preparations for the
prevention and treatment of gastrointestinal conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of hepatic conditions, diseases,
and disorders; pharmaceutical preparations for the
prevention and treatment of immunological conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of infectious diseases;
pharmaceutical preparations for the prevention and treatment
of inflammatory conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of metabolic conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of muscular conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of neurological conditions, diseases, and disorders;
pharmaceutical preparations for the treatment of pain;
pharmaceutical preparations for the prevention and treatment
of psychiatric conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of respiratory and pulmonary conditions, diseases, and
disorders; pharmaceutical preparations for the prevention
and treatment of renal conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of urological conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical
preparations for the prevention and treatment of allergies;
pharmaceutical preparations for the prevention and treatment
of autoimmune conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of blood conditions, diseases and disorders; pharmaceutical
preparations for the prevention and treatment of
cardiovascular diseases and disorders; pharmaceutical
preparations for the prevention and treatment of conditions,
diseases, and disorders of the central and peripheral
nervous system; pharmaceutical preparations for the
prevention and treatment of dermatological conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of endocrine conditions, diseases,
and disorders; pharmaceutical preparations for the
prevention and treatment of gastrointestinal conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of hepatic conditions, diseases,
and disorders; pharmaceutical preparations for the
prevention and treatment of immunological conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of infectious diseases;
pharmaceutical preparations for the prevention and treatment
of inflammatory conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of metabolic conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of muscular conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of neurological conditions, diseases, and disorders;
pharmaceutical preparations for the treatment of pain;
pharmaceutical preparations for the prevention and treatment
of psychiatric conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of respiratory and pulmonary conditions, diseases, and
disorders; pharmaceutical preparations for the prevention
and treatment of renal conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of urological conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical
preparations for the prevention and treatment of allergies;
pharmaceutical preparations for the prevention and treatment
of autoimmune conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of blood conditions, diseases and disorders; pharmaceutical
preparations for the prevention and treatment of
cardiovascular diseases and disorders; pharmaceutical
preparations for the prevention and treatment of conditions,
diseases, and disorders of the central and peripheral
nervous system; pharmaceutical preparations for the
prevention and treatment of dermatological conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of endocrine conditions, diseases,
and disorders; pharmaceutical preparations for the
prevention and treatment of gastrointestinal conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of hepatic conditions, diseases,
and disorders; pharmaceutical preparations for the
prevention and treatment of immunological conditions,
diseases, and disorders; pharmaceutical preparations for the
prevention and treatment of infectious diseases;
pharmaceutical preparations for the prevention and treatment
of inflammatory conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of metabolic conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of muscular conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of neurological conditions, diseases, and disorders;
pharmaceutical preparations for the treatment of pain;
pharmaceutical preparations for the prevention and treatment
of psychiatric conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of respiratory and pulmonary conditions, diseases, and
disorders; pharmaceutical preparations for the prevention
and treatment of renal conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of urological conditions, diseases, and disorders;
pharmaceutical preparations for the prevention and treatment
of viral diseases.
The invention provides low-dose formulations of guanylate cyclase-C (“GCC”) agonist peptides and methods for their use. The formulations of the invention can be administered either alone or in combination with one or more additional therapeutic agents, preferably an inhibitor of cGMP-dependent phosphodiesterase or a laxative.
A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
A61K 31/501 - PyridazinesHydrogenated pyridazines not condensed and containing further heterocyclic rings
A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
A61K 31/53 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
39.
TOPICAL COMPOSITIONS AND METHODS FOR TREATING SKIN DISEASES
Topical pharmaceutical compositions include tazarotene or a pharmaceutically acceptable salt of tazarotenic acid and an oil-in-water emulsion vehicle that forms a lotion. The compositions are used to treat skin diseases, such as acne vulgaris.
A61K 31/4436 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
A61K 47/06 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical substances and preparations to treat pain and
inflammation of the mouth and throat; pharmaceutical
products with anti-inflammatory, analgesic, anesthetic and
antiseptic function.
The disclosure provides a formulation and method for treating dermatological conditions, such as atopic dermatitis, in a patient comprising administering to the affected area of a patient a topical pharmaceutical composition comprising a therapeutically active vehicle and, optionally, one or more additional active agents.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/436 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
The disclosure provides a topical gel formulation comprising 1-1.5 wt. % clindamycin phosphate, 2.5-3.5 wt. % benzoyl peroxide, and 0.1-0.2 wt. % adapalene, in combination with a gelling agent, a polyhydric alcohol, and water, useful in treating inflammatory skin conditions, including acne, together with methods of making and using the same.
A61K 31/7056 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical preparations for the prevention and treatment of allergies; pharmaceutical preparations for the prevention and treatment of autoimmune conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of blood conditions, diseases and disorders; pharmaceutical preparations for the prevention and treatment of cardiovascular diseases and disorders; pharmaceutical preparations for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; pharmaceutical preparations for the prevention and treatment of dermatological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of endocrine conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of hepatic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of immunological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of infectious diseases; pharmaceutical preparations for the prevention and treatment of inflammatory conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of metabolic conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of muscular conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of neurological conditions, diseases, and disorders; pharmaceutical preparations for the treatment of pain; pharmaceutical preparations for the prevention and treatment of psychiatric conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of renal conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of urological conditions, diseases, and disorders; pharmaceutical preparations for the prevention and treatment of viral diseases.
53.
AMISELIMOD FOR PREVENTING, TREATING OR AMELIORATING ULCERATIVE COLITIS
Described herein are methods for treating, ameliorating, and/or preventing ulcerative colitis (UC) as well as other inflammatory gastrointestinal disorders using amiselimod. The method of treatment includes dosing amiselimod at a larger initial dose as compared to the eventual maintenance dose.
The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Non-medicated skin care preparations; non-medicated oral
care preparations; oral hygiene preparations; cosmetics. Pharmaceutical products and medicines for human use;
medicated skin care preparations; medicated oral care
preparations; nutritional supplements; dietetic supplements;
vitamins; medicated beverages; diagnostic preparations for
medical purposes. Surgical apparatus and instruments; medical apparatus for
the delivery and release of pharmaceuticals; medical
apparatus for facilitating the inhalation of pharmaceutical
preparations; medical apparatus for the treatment of
respiratory conditions; medical diagnostic apparatus for
medical purposes; medical devices for non-surgical cosmetic
skin treatments; lasers for the medical and cosmetic
treatment of the face and skin; radiofrequency apparatus for
the medical and cosmetic treatment of the face and skin;
electromagnetic wave therapeutic instruments; liposuction
apparatus; apparatus for the treatment of cellulite; medical
apparatus and instruments for body toning and body shaping;
apparatus for non-invasive surgery; apparatus for the
therapeutic stimulation of the body. Pharmaceutical research and development; research and
development services relating to medicines; conducting
clinical trials for pharmaceutical products; testing of
pharmaceuticals; medical and scientific research and
analysis for the prevention, diagnosis, treatment and
management of illness and disease; providing medical and
scientific research information in the field of
pharmaceuticals and clinical trials; conducting early
evaluations in the field of new pharmaceuticals;
pharmaceutical drug delivery system development services;
product research and development in the field of beauty,
wellness, and health care products. Providing medical information; providing health information;
consultancy and information services relating to medical
products; providing medical and health information and
treatment support programs to consumers and healthcare
professionals regarding pharmaceutical products; medical
services, namely, providing educational information
regarding prescription drugs and disease prevention,
diagnosis, screening, and treatment; providing information
relating to diagnostic, prophylactic and therapeutic
properties of pharmaceuticals; providing medical and health
information in the field of illness and disease prevention,
screening, diagnosis, and treatment; providing medical and
health information and treatment support programs to
consumers and healthcare professionals regarding medical
aesthetics treatments and procedures; providing medical and
health information to consumers and healthcare professionals
regarding dental treatment, dental hygiene, and oral health;
medical testing services relating to the diagnosis and
treatment of illness and disease; providing information in
the fields of health and wellness; cosmetic facial and body
treatment services; non-invasive cosmetic medical services;
aesthetic and therapeutic skin and body treatment services;
laser skin rejuvenation service; laser skin tightening
service; medical treatment services.
The disclosure provides a topical gel formulation comprising 1-1.5 wt. % clindamycin phosphate, 2.5-3.5 wt. % benzoyl peroxide, and 0.1-0.2 wt. % adapalene, in combination with a gelling agent, a polyhydric alcohol, and water, useful in treating inflammatory skin conditions, including acne, together with methods of making and using the same.
A61K 31/7056 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances; pharmaceutical products used in diseases of the gastrointestinal tract; medicines used in diseases of the gastrointestinal tract; medicinal products used in diseases of the gastrointestinal tract; herbal extracts for medical purposes used in diseases of the gastrointestinal tract; herbal food substances for the preparation of food supplements and pharmaceutical products used in diseases of the gastrointestinal tract; dietetic products adapted for medical use, used in diseases of the gastrointestinal tract.
58.
USE OF A FIXED COMBINATION OF HALOBETASOL PROPIONATE AND TAZAROTENE TO TREAT CONDITIONS MEDIATED BY INTERLEUKIN-17A
The invention relates generally to compositions and their therapeutic use. More particularly, the invention relates to compositions that modulate the activity of IL-17 and/or are useful in the treatment of skin diseases and conditions, such as inflammatory, autoimmune diseases, or oncological diseases and conditions, and other IL-17-associated disorders.
A61K 31/4436 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 9/00 - Medicinal preparations characterised by special physical form
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances for use in
dermatological conditions and skin care disorders;
pharmaceutical preparations and substances for the
prevention and treatment of dermatological conditions and
skin care disorders; pharmaceutical preparations and
substances for dermatologic use, namely, topical
preparations for the treatment of acne.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances for use in
dermatological conditions and skin care disorders;
pharmaceutical preparations and substances for the
prevention and treatment of dermatological conditions and
skin care disorders; pharmaceutical preparations and
substances for dermatologic use, namely, topical
preparations for the treatment of acne.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical substances and preparations to treat pain and inflammation of the mouth and throat; pharmaceutical products with anti-inflammatory, analgesic, anesthetic and antiseptic function.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Pharmaceutical preparations and substances for dermatology and skin disorders, skin conditions, skin care and acne; pharmaceutical preparations and substances for the prevention and treatment of skin disorders, conditions, injuries, illnesses and ailments; pharmaceutical preparations and substances for the prevention and treatment of dermatological disorders and diseases and dermatitis; pharmaceutical preparations and substances for the prevention and treatment of acne; dermatological, skin care and acne pharmaceutical preparations and substances.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Non-medicated skin care preparations; non-medicated oral
care preparations; oral hygiene preparations; cosmetics. Pharmaceutical products and medicines for human use;
medicated skin care preparations; medicated oral care
preparations; nutritional supplements; dietetic supplements;
vitamins. Surgical apparatus and instruments; medical apparatus for
the delivery and release of pharmaceuticals; medical devices
for non-surgical cosmetic skin treatments; lasers for the
medical and cosmetic treatment of the face and skin;
radiofrequency apparatus for the medical and cosmetic
treatment of the face and skin; electromagnetic wave
therapeutic instruments; liposuction apparatus; apparatus
for the treatment of cellulite; medical apparatus and
instruments for body toning and body shaping. Pharmaceutical research and development; conducting clinical
trials for pharmaceutical products; testing of
pharmaceuticals; providing medical and scientific research
information on the field of pharmaceuticals and clinical
trials; conducting early evaluations in the field of new
pharmaceuticals; pharmaceutical drug delivery system
development services; product research and development in
the field of beauty, wellness, and health care products. Providing medical and health information and treatment
support programs to consumers and healthcare professionals
regarding pharmaceutical products; medical services, namely,
providing educational information regarding prescription
drugs and disease treatment; providing medical and health
information and treatment support programs to consumers and
healthcare professionals regarding medical aesthetics
treatments and procedures; providing medical and health
information to consumers and healthcare professionals
regarding dental treatment, dental hygiene, and oral health;
providing information in the fields of health, and wellness;
non-invasive cosmetic medical services; aesthetic and
therapeutic skin and body treatment services; laser skin
rejuvenation service; laser skin tightening service.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Non-medicated skin care preparations; non-medicated oral care preparations, namely, toothpaste, mouthwash, dental rinse; oral hygiene preparations, namely, toothpaste, mouthwash, dental rinse; cosmetics Pharmaceutical products and medicines for human use for the prevention and treatment of allergies; Pharmaceutical products and medicines for human use for the prevention and treatment of autoimmune conditions, diseases, and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of blood conditions, diseases and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of cardiovascular diseases and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of conditions, diseases, and disorders of the central and peripheral nervous system; Pharmaceutical products and medicines for human use for the prevention and treatment of dermatological conditions, diseases, and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of endocrine conditions, diseases, and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of gastrointestinal conditions, diseases, and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of hepatic conditions, diseases, and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of immunological conditions, diseases, and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of infectious diseases; Pharmaceutical products and medicines for human use for the prevention and treatment of inflammatory conditions, diseases, and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of metabolic conditions, diseases, and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of neurological conditions, diseases, and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of pain; Pharmaceutical products and medicines for human use for the prevention and treatment of psychiatric conditions, diseases, and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of respiratory and pulmonary conditions, diseases, and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of renal conditions, diseases, and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of urological conditions, diseases, and disorders; Pharmaceutical products and medicines for human use for the prevention and treatment of viral diseases; Pharmaceutical products and medicines for human use, namely, antibiotics; Pharmaceutical products and medicines for human use, namely, medicated beverages, powders, and gels for colonoscopies and endoscopic procedures; medicated skin care preparations; medicated oral care preparations, namely mouthwash, dental rinses; nutritional supplements; dietary supplements; vitamins; diagnostic preparations for medical purposes Surgical apparatus and instruments;
medical apparatus for the delivery and release of pharmaceuticals, namely, drug delivery patches sold
without medication, inhalers for medical use sold empty, intravenous bags sold empty for intravenous
therapy, syringes; medical apparatus for facilitating the inhalation of pharmaceutical preparations;
medical apparatus for the treatment of respiratory conditions; medical diagnostic apparatus for medical
purposes for testing of blood sugar levels, respiratory health, liver function, kidney function, viruses,
cancer cells, DNA, antibody levels; medical devices for non-surgical cosmetic skin treatments; lasers
for the medical and cosmetic treatment of the face and skin; radiofrequency apparatus for the medical
and cosmetic treatment of the face and skin; high frequency electromagnetic wave therapeutic
instruments; medical devices and equipment for liposuction; apparatus for the treatment of cellulite;
medical apparatus and instruments using radiofrequency energy for body toning and body shaping;
apparatus for non-invasive surgery, namely for body toning and body shaping; medical apparatus
generating electromagnetic, magnetic, electrical, mechanical or thermal energy for the therapeutic
stimulation of the body Pharmaceutical research and development; research and development services relating to medicines; conducting clinical trials for others for pharmaceutical products; testing of pharmaceuticals; medical and scientific research and analysis for the prevention, diagnosis, treatment and management of illness and disease; providing medical and scientific research information in the field of pharmaceuticals and clinical trials; conducting early evaluations in the field of new pharmaceuticals; pharmaceutical drug delivery system development services; product research and development in the field of beauty, wellness, and health care products Providing medical information; providing health information; consultancy and medical information services relating to medical products; providing medical and health information and treatment support programs to consumers and healthcare professionals regarding pharmaceutical products; medical services, namely, providing medical information regarding prescription drugs and disease prevention, diagnosis, screening, and treatment; providing information relating to diagnostic, prophylactic and therapeutic properties of pharmaceuticals; providing medical and health information in the field of illness and disease prevention, screening, diagnosis, and treatment; providing medical and health information and treatment support programs to consumers and healthcare professionals regarding medical aesthetics treatments and procedures; providing medical and health information to consumers and healthcare professionals regarding dental treatment, dental hygiene, and oral health; medical testing services relating to the diagnosis and treatment of illness and disease; providing information in the fields of health and wellness; cosmetic facial and body treatment services; non-invasive cosmetic medical services; aesthetic and therapeutic skin and body treatment services; laser skin rejuvenation service; laser skin tightening service; medical treatment services, namely energy-based procedures for treatment of the face, body, tissue and skin
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Non-medicated skin care preparations; non-medicated oral care preparations; oral hygiene preparations; cosmetics.
(2) Pharmaceutical products and medicines for human use; medicated skin care preparations; medicated oral care preparations; nutritional supplements; dietetic supplements; vitamins; medicated beverages; diagnostic preparations for medical purposes.
(3) Surgical apparatus and instruments; medical apparatus for the delivery and release of pharmaceuticals; medical apparatus for facilitating the inhalation of pharmaceutical preparations; medical apparatus for the treatment of respiratory conditions; medical diagnostic apparatus for medical purposes; medical devices for non-surgical cosmetic skin treatments; lasers for the medical and cosmetic treatment of the face and skin; radiofrequency apparatus for the medical and cosmetic treatment of the face and skin; electromagnetic wave therapeutic instruments; liposuction apparatus; apparatus for the treatment of cellulite; medical apparatus and instruments for body toning and body shaping; apparatus for non-invasive surgery; apparatus for the therapeutic stimulation of the body. (1) Pharmaceutical research and development; research and development services relating to medicines; conducting clinical trials for pharmaceutical products; testing of pharmaceuticals; medical and scientific research and analysis for the prevention, diagnosis, treatment and management of illness and disease; providing medical and scientific research information in the field of pharmaceuticals and clinical trials; conducting early evaluations in the field of new pharmaceuticals; pharmaceutical drug delivery system development services; product research and development in the field of beauty, wellness, and health care products.
(2) Providing medical information; providing health information; consultancy and information services relating to medical products; providing medical and health information and treatment support programs to consumers and healthcare professionals regarding pharmaceutical products; medical services, namely, providing educational information regarding prescription drugs and disease prevention, diagnosis, screening, and treatment; providing information relating to diagnostic, prophylactic and therapeutic properties of pharmaceuticals; providing medical and health information in the field of illness and disease prevention, screening, diagnosis, and treatment; providing medical and health information and treatment support programs to consumers and healthcare professionals regarding medical aesthetics treatments and procedures; providing medical and health information to consumers and healthcare professionals regarding dental treatment, dental hygiene, and oral health; medical testing services relating to the diagnosis and treatment of illness and disease; providing information in the fields of health and wellness; cosmetic facial and body treatment services; non-invasive cosmetic medical services; aesthetic and therapeutic skin and body treatment services; laser skin rejuvenation service; laser skin tightening service; medical treatment services.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances for use in dermatological conditions and skin care disorders; pharmaceutical preparations and substances for the prevention and treatment of dermatological conditions and skin care disorders; pharmaceutical preparations and substances for dermatologic use, namely, topical preparations for the treatment of acne.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances for use in dermatological conditions and skin care disorders; pharmaceutical preparations and substances for the prevention and treatment of dermatological conditions and skin care disorders; pharmaceutical preparations and substances for dermatologic use, namely, topical preparations for the treatment of acne.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Non-medicated skin care preparations; non-medicated oral
care preparations; oral hygiene preparations; cosmetics. Pharmaceutical products and medicines for human use;
medicated skin care preparations; medicated oral care
preparations; nutritional supplements; dietetic supplements;
vitamins. Surgical apparatus and instruments; medical apparatus for
the delivery and release of pharmaceuticals; medical devices
for non-surgical cosmetic skin treatments; lasers for the
medical and cosmetic treatment of the face and skin;
radiofrequency apparatus for the medical and cosmetic
treatment of the face and skin; electromagnetic wave
therapeutic instruments; liposuction apparatus; apparatus
for the treatment of cellulite; medical apparatus and
instruments for body toning and body shaping. Pharmaceutical research and development; conducting clinical
trials for pharmaceutical products; testing of
pharmaceuticals; providing medical and scientific research
information on the field of pharmaceuticals and clinical
trials; conducting early evaluations in the field of new
pharmaceuticals; pharmaceutical drug delivery system
development services; product research and development in
the field of beauty, wellness, and health care products. Providing medical and health information and treatment
support programs to consumers and healthcare professionals
regarding pharmaceutical products; medical services, namely,
providing educational information regarding prescription
drugs and disease treatment; providing medical and health
information and treatment support programs to consumers and
healthcare professionals regarding medical aesthetics
treatments and procedures; providing medical and health
information to consumers and healthcare professionals
regarding dental treatment, dental hygiene, and oral health;
providing information in the fields of health, and wellness;
non-invasive cosmetic medical services; aesthetic and
therapeutic skin and body treatment services; laser skin
rejuvenation service; laser skin tightening service.
Methods are provided for treating acne vulgaris in subjects having acne vulgaris and oily skin and for treating truncal acne. Compositions comprising tazarotene or a pharmaceutically acceptable salt of tazarotenic acid in an oily-in-water emulsion are also provided for use in the methods for treating acne vulgaris in subjects having acne vulgaris and oils skin and in the methods for treating truncal acne.
A61K 31/4436 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 47/00 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations for treating gastrointestinal disorders; Gastrointestinal preparations; Pharmaceutical preparations for the treatment of digestive diseases; Medicines for the treatment of gastrointestinal diseases; Medicines for intestinal disorders.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Non-medicated skin care preparations; cosmetic ingredient complex composed of antioxidants, humectants, emollients, essential oils, collagen, retinol, salicylic acid, benzoyl peroxide, and hyaluronic acid sold as an integral component of non-medicated skin care preparations Pharmaceutical preparations and substances for the treatment of dermatological conditions and skin care disorders; pharmaceutical preparations and substances for the prevention and treatment of dermatological conditions and skin care disorders; medicated dermatological preparations and substances
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Non-medicated skin care preparations; non-medicated oral care preparations; non-medicated oral hygiene preparations, namely, toothpaste, mouthwash, dental rinse; cosmetics pharmaceutical products and medicines for human use for prevention and treatment of allergic, autoimmune, bronchial, bone, cancer, cardiovascular, central nervous system, dermatological, endocrine, gastrointestinal, genitourinary, gynecological, hematological, hepatological, immunological, infectious, inflammatory, mental, metabolic, musculoskeletal, nephrological, neurological, neuromuscular, oncological, ophthalmic, oral, pain, psychiatric, pulmonary, renal, respiratory, urological, and viral diseases and disorders; Pharmaceutical products and medicines for human use for colonoscopies and endoscopic procedures; medicated skin care preparations; medicated oral care preparations; nutritional supplements; dietetic supplements, namely, dietetic preparations adapted for medical purposes; vitamins Surgical apparatus and instruments; medical apparatus for the delivery and release of pharmaceuticals, namely, drug delivery patches sold without medication, inhalers for medical use sold empty, intravenous bags sold empty for intravenous therapy, syringes; medical devices for non-surgical cosmetic skin treatments; lasers for the medical treatment of the face and skin; radiofrequency therapy apparatus for the medical and cosmetic treatment of the face and skin, in particular for contracting skin, smoothing fine lines and wrinkles on skin, body sculpting, and soft tissue reconstruction in a non-invasive manner; high frequency electromagnetic wave therapeutic instruments; liposuction apparatus; medical radiofrequency, laser, and ultrasound therapy apparatus for the treatment of cellulite; medical apparatus and instruments for body toning and body shaping Pharmaceutical research and development; medical and scientific research, namely, conducting clinical trials for pharmaceutical products for others; testing of pharmaceuticals; providing medical and scientific research information on the field of pharmaceuticals and clinical trials; conducting early evaluations in the field of new pharmaceuticals; developments of pharmaceutical drug delivery systems; product research and development services for others in the field of beauty, wellness, and health care products Providing medical and health information to consumers and healthcare professionals regarding pharmaceutical products; medical information services, namely, providing medical and healthcare information regarding prescription drugs and disease treatment; providing medical and health information to consumers and healthcare professionals regarding medical aesthetics treatments and procedures; providing medical and health information to consumers and healthcare professionals regarding dental treatment, dental hygiene, and oral health; providing information in the fields of health, and wellness; performing non-invasive cosmetic medical procedures; medical clinic services, namely, cosmetic and therapeutic skin and body care treatment; laser skin rejuvenation service; laser skin tightening service
97.
AGONISTS OF GUANYLATE CYCLASE USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS, INFLAMMATION, CANCER AND OTHER DISORDERS
The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cGMP-dependent phosphodiesterase. The gastrointestinal disorder may be classified as either irritable bowel syndrome, constipation, or excessive acidity etc. The gastrointestinal disease may be classified as either inflammatory bowel disease or other GI condition, including Crohn's disease and ulcerative colitis, and cancer.
C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
A61K 47/60 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
C07K 7/64 - Cyclic peptides containing only normal peptide links
A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Non-medicated skin care preparations; non-medicated oral care preparations; oral hygiene preparations; cosmetics.
(2) Pharmaceutical products and medicines for human use; medicated skin care preparations; medicated oral care preparations; nutritional supplements; dietetic supplements; vitamins.
(3) Surgical apparatus and instruments; medical apparatus for the delivery and release of pharmaceuticals; medical devices for non-surgical cosmetic skin treatments; lasers for the medical and cosmetic treatment of the face and skin; radiofrequency apparatus for the medical and cosmetic treatment of the face and skin; electromagnetic wave therapeutic instruments; liposuction apparatus; apparatus for the treatment of cellulite; medical apparatus and instruments for body toning and body shaping. (1) Pharmaceutical research and development; conducting clinical trials for pharmaceutical products; testing of pharmaceuticals; providing medical and scientific research information on the field of pharmaceuticals and clinical trials; conducting early evaluations in the field of new pharmaceuticals; pharmaceutical drug delivery system development services; product research and development in the field of beauty, wellness, and health care products.
(2) Providing medical and health information and treatment support programs to consumers and healthcare professionals regarding pharmaceutical products; medical services, namely, providing educational information regarding prescription drugs and disease treatment; providing medical and health information and treatment support programs to consumers and healthcare professionals regarding medical aesthetics treatments and procedures; providing medical and health information to consumers and healthcare professionals regarding dental treatment, dental hygiene, and oral health; providing information in the fields of health, and wellness; non-invasive cosmetic medical services; aesthetic and therapeutic skin and body treatment services; laser skin rejuvenation service; laser skin tightening service.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Non-medicated skin care preparations; non-medicated oral care preparations; oral hygiene preparations; cosmetics.
(2) Pharmaceutical products and medicines for human use; medicated skin care preparations; medicated oral care preparations; nutritional supplements; dietetic supplements; vitamins.
(3) Surgical apparatus and instruments; medical apparatus for the delivery and release of pharmaceuticals; medical devices for non-surgical cosmetic skin treatments; lasers for the medical and cosmetic treatment of the face and skin; radiofrequency apparatus for the medical and cosmetic treatment of the face and skin; electromagnetic wave therapeutic instruments; liposuction apparatus; apparatus for the treatment of cellulite; medical apparatus and instruments for body toning and body shaping. (1) Pharmaceutical research and development; conducting clinical trials for pharmaceutical products; testing of pharmaceuticals; providing medical and scientific research information on the field of pharmaceuticals and clinical trials; conducting early evaluations in the field of new pharmaceuticals; pharmaceutical drug delivery system development services; product research and development in the field of beauty, wellness, and health care products.
(2) Providing medical and health information and treatment support programs to consumers and healthcare professionals regarding pharmaceutical products; medical services, namely, providing educational information regarding prescription drugs and disease treatment; providing medical and health information and treatment support programs to consumers and healthcare professionals regarding medical aesthetics treatments and procedures; providing medical and health information to consumers and healthcare professionals regarding dental treatment, dental hygiene, and oral health; providing information in the fields of health, and wellness; non-invasive cosmetic medical services; aesthetic and therapeutic skin and body treatment services; laser skin rejuvenation service; laser skin tightening service.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Non-medicated skin care preparations; non-medicated oral care preparations; non-medicated oral hygiene preparations, namely, toothpaste, mouthwash, dental rinse; cosmetics pharmaceutical products and medicines for human use for prevention and treatment of allergic, autoimmune, bronchial, bone, cancer, cardiovascular, central nervous system, dermatological, endocrine, gastrointestinal, genitourinary, gynecological, hematological, hepatological, immunological, infectious, inflammatory, mental, metabolic, musculoskeletal, nephrological, neurological, neuromuscular, oncological, ophthalmic, oral, pain, psychiatric, pulmonary, renal, respiratory, urological, and viral diseases and disorders; Pharmaceutical products and medicines for human use for colonoscopies and endoscopic procedures; medicated skin care preparations; medicated oral care preparations; nutritional supplements; dietetic supplements, namely, dietetic preparations adapted for medical purposes; vitamins Surgical apparatus and instruments; medical apparatus for the delivery and release of pharmaceuticals, namely, drug delivery patches sold without medication, inhalers for medical use sold empty, intravenous bags sold empty for intravenous therapy, syringes; medical devices for non-surgical cosmetic skin treatments; lasers for the medical treatment of the face and skin; radiofrequency therapy apparatus for the medical and cosmetic treatment of the face and skin, in particular for contracting skin, smoothing fine lines and wrinkles on skin, body sculpting, and soft tissue reconstruction in a non-invasive manner; high frequency electromagnetic wave therapeutic instruments; liposuction apparatus; medical radiofrequency, laser, and ultrasound therapy apparatus for the treatment of cellulite; medical apparatus and instruments for body toning and body shaping Pharmaceutical research and development; medical and scientific research, namely, conducting clinical trials for pharmaceutical products for others; testing of pharmaceuticals; providing medical and scientific research information on the field of pharmaceuticals and clinical trials; conducting early evaluations in the field of new pharmaceuticals; developments of pharmaceutical drug delivery systems; product research and development services for others in the field of beauty, wellness, and health care products Providing medical and health information to consumers and healthcare professionals regarding pharmaceutical products; medical information services, namely, providing medical and healthcare information regarding prescription drugs and disease treatment; providing medical and health information to consumers and healthcare professionals regarding medical aesthetics treatments and procedures; providing medical and health information to consumers and healthcare professionals regarding dental treatment, dental hygiene, and oral health; providing information in the fields of health, and wellness; performing non-invasive cosmetic medical procedures; medical clinic services, namely, cosmetic and therapeutic skin and body care treatment; laser skin rejuvenation service; laser skin tightening service