Jiangsu Jland Biotech Co., Ltd.

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IP Type
        Trademark 13
        Patent 4
Jurisdiction
        United States 9
        World 8
Date
2021 2
2020 3
Before 2020 12
IPC Class
C07K 14/78 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG] 4
C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione 4
C12R 1/84 - Pichia 4
C12N 1/16 - YeastsCulture media therefor 2
C07K 1/34 - ExtractionSeparationPurification by filtration, ultrafiltration or reverse osmosis 1
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NICE Class
01 - Chemical and biological materials for industrial, scientific and agricultural use 10
05 - Pharmaceutical, veterinary and sanitary products 4
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations 3
10 - Medical apparatus and instruments 2

1.

DEMULCENT

      
Application Number 1605968
Status Registered
Filing Date 2021-07-13
Registration Date 2021-07-13
Owner Jiangsu Jland Biotech Co., Ltd. (China)
NICE Classes  ?
  • 01 - Chemical and biological materials for industrial, scientific and agricultural use
  • 10 - Medical apparatus and instruments

Goods & Services

Tensio-active agents; protein [raw material]; collagen for industrial purposes; emulsifiers; cultures of microorganisms, other than for medical and veterinary use; chemical preparations for scientific purposes, other than for medical or veterinary use; proteins for the food industry; proteins for use in the manufacture of food supplements; preservatives for pharmaceutical preparations; gelatine for industrial purposes. Medical apparatus and instruments; artificial teeth; dental apparatus and instruments; dental burs; surgical sponges; surgical implants comprised of artificial materials; artificial eyes; artificial skin for surgical purposes; suture materials; thread, surgical.

2.

DEMULCENT

      
Serial Number 79317288
Status Registered
Filing Date 2021-07-13
Registration Date 2022-12-20
Owner Jiangsu Jland Biotech Co., Ltd. (China)
NICE Classes  ?
  • 01 - Chemical and biological materials for industrial, scientific and agricultural use
  • 10 - Medical apparatus and instruments

Goods & Services

Tensio-active agents, namely, non-ionic surfactants as raw materials for use in the manufacture of cosmetics; Protein in raw material form for scientific and medical research; collagen for industrial purposes; emulsifiers for use in for industrial manufacturing; cultures of microorganisms, other than for medical and veterinary use; chemical preparations for scientific purposes, other than for medical or veterinary use; proteins for the food industry; proteins for use in the manufacture of food supplements; preservatives for pharmaceutical preparations, namely, chemical preparations for preserving foodstuffs; gelatine for industrial purposes Medical apparatus and instruments, namely, devices for repairing damaged skin; artificial teeth; dental apparatus and instruments, namely, artificial teeth; dental burs; surgical sponges; surgical implants comprised of artificial materials; artificial eyes; artificial skin for surgical purposes; suture materials; thread, surgical

3.

Friz-well

      
Application Number 1566063
Status Registered
Filing Date 2020-06-29
Registration Date 2020-06-29
Owner Jiangsu Jland Biotech Co., Ltd. (China)
NICE Classes  ? 03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations

Goods & Services

Cleansing milk for toilet purposes; shampoo; facial cleanser; oils for cleaning purposes; essential oils; beauty masks; cosmetics; collagen preparations for cosmetic purposes; anti-wrinkle cream; dentifrices.

4.

FRIZ-WELL

      
Serial Number 79300360
Status Registered
Filing Date 2020-06-29
Registration Date 2021-04-20
Owner Jiangsu Jland Biotech Co., Ltd. (China)
NICE Classes  ? 03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations

Goods & Services

Cleansing milk for toilet purposes; shampoo; facial cleanser; oils for cleaning purposes; essential oils; beauty masks; cosmetics; collagen preparations for cosmetic purposes; anti-wrinkle cream; dentifrices

5.

Friz-well

      
Application Number 1521052
Status Registered
Filing Date 2019-11-04
Registration Date 2019-11-04
Owner Jiangsu Jland Biotech Co., Ltd. (China)
NICE Classes  ? 03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations

Goods & Services

Facial cleanser; oils for cleaning purposes; shampoo; cleansing milk for toilet purposes; essential oils; beauty masks; cosmetics; anti-wrinkle cream; dentifrices; collagen preparations for cosmetic purposes.

6.

Besicol

      
Application Number 1503846
Status Registered
Filing Date 2019-09-09
Registration Date 2019-09-09
Owner Jiangsu Jland Biotech Co., Ltd. (China)
NICE Classes  ?
  • 01 - Chemical and biological materials for industrial, scientific and agricultural use
  • 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Protein [raw material]; collagen for industrial purposes; tensio-active agents; emulsifiers; chemical preparations for scientific purposes, other than for medical or veterinary use; cultures of microorganisms, other than for medical and veterinary use; preservatives for use in the pharmaceutical industry; proteins for use in the manufacture of food supplements; proteins for the food industry; gelatine for industrial purposes. Nutraceutical preparations for therapeutic or medical purposes; protein dietary supplements; collagen for medical purposes; drugs for medical purposes; gelatine for medical purposes; peptones for pharmaceutical purposes; adjuvants for medical purposes; crude drug; albuminous foodstuffs for medical purposes; teeth filling material.

7.

Pepwell

      
Application Number 1503036
Status Registered
Filing Date 2019-11-20
Registration Date 2019-11-20
Owner Jiangsu Jland Biotech Co., Ltd. (China)
NICE Classes  ?
  • 01 - Chemical and biological materials for industrial, scientific and agricultural use
  • 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Protein [raw material]; collagen for industrial purposes; tensio-active agents; emulsifiers; chemical preparations for scientific purposes, other than for medical or veterinary use; cultures of microorganisms, other than for medical and veterinary use; preservatives for pharmaceutical preparations; proteins for use in the manufacture of food supplements; proteins for the food industry; gelatine for industrial purposes. Nutraceutical preparations for therapeutic or medical purposes; protein dietary supplements; collagen for medical purposes; drugs for medical purposes; gelatine for medical purposes; peptones for pharmaceutical purposes; adjuvants for medical purposes; crude drug; albuminous foodstuffs for medical purposes; teeth filling material.

8.

Biollagen

      
Application Number 1503117
Status Registered
Filing Date 2019-11-20
Registration Date 2019-11-20
Owner Jiangsu Jland Biotech Co., Ltd. (China)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

Protein [raw material]; tensio-active agents; collagen for industrial purposes; emulsifiers; chemical preparations for scientific purposes, other than for medical or veterinary use; preservatives for pharmaceutical preparations; proteins for use in the manufacture of food supplements; proteins for the food industry; gelatine for industrial purposes; cultures of microorganisms, other than for medical and veterinary use.

9.

PEPWELL

      
Serial Number 79273915
Status Registered
Filing Date 2019-11-20
Registration Date 2021-03-30
Owner Jiangsu Jland Biotech Co., Ltd. (China)
NICE Classes  ?
  • 01 - Chemical and biological materials for industrial, scientific and agricultural use
  • 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Protein in raw material form for use in the manufacture of cosmetics; collagen for industrial purposes; tensio-active agents for use in the manufacture of cosmetics products; emulsifiers for use in the manufacture of cosmetics products; chemical preparations for scientific purposes, other than for medical or veterinary use; cultures of microorganisms, other than for medical and veterinary use; preservatives for pharmaceutical preparations; proteins for use in the manufacture of food supplements; proteins for the food industry; gelatine for industrial purposes Nutraceutical preparations for therapeutic or medical purposes; protein dietary supplements; collagen for medical purposes; drugs for medical purposes, namely, health care medicine for the treatment of gastrointestinal diseases; gelatine for medical purposes; peptones for pharmaceutical purposes for treatment of skin diseases; adjuvants for medical purposes; crude drugs being medicated cosmetics; albuminous foodstuffs for medical purposes; teeth filling material

10.

BIOLLAGEN

      
Serial Number 79273938
Status Registered
Filing Date 2019-11-20
Registration Date 2021-03-30
Owner Jiangsu Jland Biotech Co., Ltd. (China)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

Protein in raw material form for use in the manufacture of cosmetics; tensio-active agents for use in the manufacture of cosmetics products; collagen for industrial purposes; emulsifiers for use in the manufacture of cosmetics products; chemical preparations for scientific purposes, other than for medical or veterinary use; preservatives for pharmaceutical preparations; proteins for use in the manufacture of food supplements; proteins for the food industry; gelatine for industrial purposes; cultures of microorganisms, other than for medical and veterinary use

11.

Fermentation process with Pichia yeast expressing recombinant protein

      
Application Number 16318549
Grant Number 11104928
Status In Force
Filing Date 2016-10-18
First Publication Date 2019-10-10
Grant Date 2021-08-31
Owner JIANGSU JLAND BIOTECH CO., LTD. (China)
Inventor
  • Yang, Shulin
  • Zhao, Jianfeng
  • Huang, Jianmin
  • Gao, Lihu
  • Du, Erfeng
  • Tao, Hai
  • Feng, Liping
  • Ji, Le
  • Zhou, Aimei

Abstract

Pichia pastoris is used as a fungal strain. The process comprises performing primary seed culturing to reach a fungal concentration of 20±2 g/L; then performing secondary seed culturing to reach a fungal concentration of 120±10 g/L; next proceeding to a glycerol culturing stage, wherein the amount of glycerol added in the glycerol culturing stage is 60-70 g/L; and then proceeding to a methanol-induced stage for 120±8 h after the dissolved oxygen quickly reaches a relatively stable state, to complete the fermentation process. In the present invention, a glycerol fed-batch addition stage in existing processes is omitted, and the process proceeds to a next stage as soon as glycerol is completely consumed, with no need to prepare sterilized glycerol for fluidic addition. As such, the glycerin sterilizer is omitted, the consumption of energy and resource and the waste of glycerin are reduced. Moreover, the fungal concentration has no need to be monitored, thus reducing the probability of errors, and lowering the fermentation failure caused by technical errors. Therefore, the present process is more suitable for large-scale industrial production, and brings convenience and great economic value for the industrial production of the recombinant protein.

IPC Classes  ?

  • C08L 89/00 - Compositions of proteinsCompositions of derivatives thereof
  • C12P 21/00 - Preparation of peptides or proteins
  • C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
  • C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
  • C07K 14/78 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
  • C12N 1/16 - YeastsCulture media therefor
  • C12R 1/84 - Pichia

12.

BESICOL

      
Serial Number 79274256
Status Registered
Filing Date 2019-09-09
Registration Date 2021-03-30
Owner Jiangsu Jland Biotech Co., Ltd. (China)
NICE Classes  ?
  • 01 - Chemical and biological materials for industrial, scientific and agricultural use
  • 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Protein in raw material form for use in the manufacture of cosmetics; collagen for industrial purposes; tensio-active agents for use in the manufacture of cosmetics products; emulsifiers for use in the manufacture of cosmetics products; chemical preparations for scientific purposes, other than for medical or veterinary use; cultures of microorganisms, other than for medical and veterinary use; preservatives for pharmaceutical preparations; proteins for use in the manufacture of food supplements; proteins for the food industry; gelatine for industrial purposes Nutraceutical preparations for therapeutic or medical purposes; protein dietary supplements; collagen for medical purposes; drugs for medical purposes, namely, health care medicine for the treatment of gastrointestinal diseases; gelatine for medical purposes; peptones for pharmaceutical purposes for treatment of skin diseases; adjuvants for medical purposes; crude drugs being medicated cosmetics; albuminous foodstuffs for medical purposes; teeth filling material

13.

Fermentation process for increasing production level of recombinant human collagen

      
Application Number 16318556
Grant Number 11136373
Status In Force
Filing Date 2016-10-18
First Publication Date 2019-08-08
Grant Date 2021-10-05
Owner JIANGSU JLAND BIOTECH CO., LTD. (China)
Inventor
  • Yang, Shulin
  • Du, Erfeng
  • Huang, Jianmin
  • Gao, Lihu
  • Zhao, Jianfeng
  • Tao, Hai
  • Feng, Liping
  • Zhou, Aimei

Abstract

The present invention provides a fermentation process for improving the production level of a recombinant human collagen. The process comprises inoculating a sterilized fermentation medium with a Pichia yeast solution, then performing fermentation culturing for 14-18 hrs, adding methanol to induce the expression, upon which sodium pyruvate is added to the fermentation medium, wherein the amount of the sodium pyruvate added is 0.01-10 g/L. In the fermentation process of the present invention, the sodium pyruvate is added in the methanol-induced expression stage, so that the biosynthesis rate of the recombinant human collagen is improved; and a continuous feed-batch mode is adopted, so that the biosynthesis rate of the recombinant human collagen is further improved, and the fermentation time is shortened. Meanwhile, the expression level of the recombinant human collagen is increased, the fermentation level is increased by more than 20%, and the production cost is reduced. The fermentation process is especially suitable for industrialized mass production of recombinant human collagen, and is of huge practical application value in industrial production.

IPC Classes  ?

  • C07K 14/78 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
  • C12N 1/16 - YeastsCulture media therefor
  • C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
  • C12R 1/84 - Pichia

14.

JLAND

      
Serial Number 88225816
Status Registered
Filing Date 2018-12-12
Registration Date 2019-10-01
Owner Jiangsu Jland Biotech Co., Ltd. (China)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

Agar-agar; Casein for industrial purposes; Collagen for industrial purposes; Gluten for industrial purposes; Pectin for industrial purposes; Protein for industrial use; Protein in raw material form for scientific and medical research; Proteins for the food industry; Proteins for use in manufacture; Chemical reagents, other than for medical or veterinary purpose

15.

REALLAGEN

      
Serial Number 88225825
Status Registered
Filing Date 2018-12-12
Registration Date 2019-10-01
Owner Jiangsu Jland Biotech Co., Ltd. (China)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

Agar-agar; Casein for industrial purposes; Collagen for industrial purposes; Gluten for industrial purposes; Pectin for industrial purposes; Protein for industrial use; Protein in raw material form for scientific and medical research; Chemical reagents, other than for medical or veterinary purpose; Proteins for use in manufacture; Proteins for the food industry

16.

FERMENTATION TECHNIQUE WITH PICHIA YEAST EXPRESSING RECOMBINANT PROTEIN

      
Application Number CN2016102430
Publication Number 2018/014452
Status In Force
Filing Date 2016-10-18
Publication Date 2018-01-25
Owner JIANGSU JLAND BIOTECH CO., LTD. (China)
Inventor
  • Yang, Shulin
  • Zhao, Jianfeng
  • Huang, Jianmin
  • Gao, Lihu
  • Du, Erfeng
  • Tao, Hai
  • Feng, Liping
  • Ji, Le
  • Zhou, Aimei

Abstract

Provided is a fermentation technique with a Pichia yeast expressing a recombinant protein. The fermentation technique uses Pichia pastoris as the fungal strain. The method comprises: performing primary seed culturing to reach a fungal concentration of 20±2 g/L, then switching to secondary seed culturing to reach a concentration of 120±2 g/L, then switching to a glycerol culturing phase, wherein the amount of glycerol added for the glycerol culturing phase is 60-70 g/L, then waiting for dissolved oxygen to reach a relatively stable state to initiate a methanol induction phase, and performing induction for 120±8 h to complete the fermentation process.

IPC Classes  ?

  • C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
  • C07K 14/78 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
  • C07K 1/34 - ExtractionSeparationPurification by filtration, ultrafiltration or reverse osmosis
  • C12R 1/84 - Pichia

17.

FERMENTATION TECHNIQUE TO IMPROVE PRODUCTION LEVEL OF RECOMBINANT HUMAN COLLAGEN

      
Application Number CN2016102435
Publication Number 2018/014453
Status In Force
Filing Date 2016-10-18
Publication Date 2018-01-25
Owner JIANGSU JLAND BIOTECH CO., LTD. (China)
Inventor
  • Yang, Shulin
  • Du, Erfeng
  • Huang, Jianmin
  • Gao, Lihu
  • Zhao, Jianfeng
  • Tao, Hai
  • Feng, Liping
  • Zhou, Aimei

Abstract

The present invention provides a fermentation technique to improve the production level of a recombinant human collagen. First inoculating a sterilized fermentation culture medium with a Pichia yeast solution, then performing fermentation culturing for 14-18 hours before adding methanol to induce the expression, and adding sodium pyruvate into the culture medium, wherein the amount of the sodium pyruvate added is 0.01-10 g/L.

IPC Classes  ?

  • C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
  • C12R 1/84 - Pichia
  • C07K 14/78 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]