41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Publication of texts, other than publicity texts; Know-how transfer [training]; Online publication of electronic books and journals; Arranging and conducting of conferences; Arranging and conducting of seminars; Arranging and conducting of workshops [training]; Arranging and conducting of congresses; Publication of books; Providing of education. Medical research; Scientific research. Plastic surgery; Cosmetic and plastic surgery; Plastic surgery services; Pharmaceutical advice.
16 - Paper, cardboard and goods made from these materials
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Printed educational materials; Educational books; Teaching materials [except apparatus]; Paper teaching materials; Professional magazines; Printed books, magazines, newspapers, and other paper-based media; Printed news releases; Information books; Medical journals; Non-fiction books. Education services relating to therapeutic treatments; Medical education services; Training and instruction; Training services for medical visitors; Education information; Educational services in the healthcare sector; Providing continuing medical education courses; Provision of training courses; Development of educational materials; Education services relating to medicine; Training in the field of medicine; Teaching services relating to the medical field; Publishing of medical publications; Publication of printed matter and printed publications; Publication of printed matter in electronic form on the Internet; Publication of printed matter, also in electronic form, except for advertising purposes; Publication of printed matter, other than publicity texts, in electronic form; Publication of manuals; Publication of magazines; Multimedia publishing; Multimedia publishing of printed matter; Writing of texts; Writing of texts, other than publicity texts; Publication of the results of clinical trials; Publishing of journals; Publishing and issuing scientific papers in relation to medical technology; Publication of printed matter; Publication of printed matter in electronic form; Publication of medical texts; Publishing of journals, books and handbooks in the field of medicine; Publication of instructional literature; Publication of training manuals; Publication of scientific information journals; Publishing scientific papers in relation to medical technology; Developing educational manuals; Training. Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; Consultancy relating to research and development in the field of therapeutics; Providing information about the results of clinical trials for pharmaceutical products; Providing information on clinical studies via an interactive website. Professional consultancy relating to health care; Human healthcare services; Physiotherapy; Medical services; Medical information services provided via the Internet; Consultancy services relating to cosmetics; Advisory services relating to beauty treatment; Consultancy services relating to beauty.
Hypodermic needles for injection; injection instruments
without needles; injection needles; injection needles for
medical use; needles for injections; medical syringe
needles; needles for surgical purposes; needles for medical
purposes; needles for medical use; needle holders for
surgical use (term considered too vague by the International
Bureau - Rule 13 (2) (b) of the Regulations); suture
materials; suture materials for medical use.
(1) Hypodermic needles for injection; injection instruments without needles; injection needles; injection needles for medical use; needles for injections; medical syringe needles; needles for surgical purposes; needles for medical purposes; needles for medical use; needle holders for surgical use (term considered too vague by the International Bureau - Rule 13 (2) (b) of the Regulations); suture materials; suture materials for medical use.
5.
THIOL-MODIFIED HYALURONAN AND HYDROGEL COMPRISING THE CROSSLINKED HYALURONAN
A thiol-modified hyaluronan, wherein the thiol-modified hyaluronan comprises a plurality of modification groups with a thiol-group in the hyaluronan side-chains, wherein the modification group comprises an amino acid residue with basic side chain and a conjugated terminal naturally occurring amino-thiol as well as a sterile hydrogel composition comprising a crosslinked polymer, wherein the crosslinked polymer is an oxidation product of the thiol-modified hyaluronan and uses of the composition.
A sterile hydrogel composition that includes a crosslinked polymer, wherein the crosslinked polymer is an oxidation product of a thiol-modified hyaluronan and wherein the thiol-modified hyaluronan has a degree of modification of hyaluronan with thiol moieties of more than about 80 μmol per gram polymer, wherein the thiol-modified hyaluronan has a degree of modification of hyaluronan with thiol moieties of less than about 280 μmol per gram polymer, and wherein the thiol-modified hyaluronan has a mean molecular weight of at least 400 kDa.
A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A61L 27/54 - Biologically active materials, e.g. therapeutic substances
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
Sterile hydrogel composition comprising crosslinked hyaluronan, wherein the amount of extractable hyaluronan having a molecular weight of less than 200 kDa is less than 15 wt. % relative to the total amount of hyaluronan.
A sterile hydrogel composition comprising a crosslinked polymer, wherein the crosslinked polymer is an oxidation product of a thiol-modified hyaluronan and wherein the thiol-modified hyaluronan has a degree of modification of hyaluronan with thiol moieties of more than about 80 μmol per gram polymer, wherein the thiol-modified hyaluronan has a degree of modification of hyaluronan with thiol moieties of less than about 280 μmol per gram polymer, wherein the composition has a residual thiol content of less than 20% in respect to the degree of modification of the thiol-modified hyaluronan.
A thiol-modified hyaluronan, wherein the thiol-modified hyaluronan comprises a plurality of modification groups with a thiol-group in the hyaluronan side-chains, wherein the modification group comprises an amino acid residue with basic side chain and a conjugated terminal naturally occurring amino-thiol as well as a sterile hydrogel composition comprising a crosslinked polymer, wherein the crosslinked polymer is an oxidation product of the thiol-modified hyaluronan and uses of the composition.
A thiol-modified hyaluronan, wherein the thiol-modified hyaluronan comprises a plurality of modification groups with a thiol-group in the hyaluronan side-chains, wherein the modification group comprises an amino acid residue with basic side chain and a conjugated terminal naturally occurring amino-thiol as well as a sterile hydrogel composition comprising a crosslinked polymer, wherein the crosslinked polymer is an oxidation product of the thiol-modified hyaluronan and uses of the composition.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
Goods & Services
Cosmetics, in particular lotions, creams and serums for the
face; cosmetic lotions, creams and serums; eye care
products, not for medical purposes; eye creams; lotions for
the eyes; night creams; day creams; cosmetics with
hyaluronic acid; cleansing creams [cosmetic]; cleansing
lotions; cleaning oils; sunscreen preparations; all of the
aforesaid goods excluding shaving cosmetics, shaving
preparations, preshave and aftershave preparations.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
Goods & Services
Cosmetics, in particular lotions, creams and serums for the face; cosmetic lotions, creams and serums; eye care products, not for medical purposes, namely, eye creams, eye lotions; eye creams; lotions for the eyes; night creams; cosmetic day creams; cosmetics with hyaluronic acid; cosmetic cleansing creams; skin cleansing lotions; cleaning oils; sunscreen preparations; all of the aforesaid goods excluding shaving cosmetics, shaving preparations, preshave and aftershave preparations
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
Goods & Services
(1) Cosmetics, namely, lotions, creams and non-medicated skin serums for the face, cosmetic lotions, creams and serums, eye care products, not for medical purposes namely, eye creams, eye lotions, eye creams, lotions for the eyes, night creams, day creams, cosmetics with hyaluronic acid, cosmetic cleansing creams, skin cleansing lotions, cosmetic oils, sunscreen preparations, all of the aforesaid goods excluding shaving cosmetics, shaving preparations, preshave and aftershave preparations.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
Goods & Services
Cosmetics, In particular lotions, creams and Facial serums; Cosmetic lotions, Creams and serums; Eye care products, non-medicated; Eye cream; Eye lotions; Night cream; Day creams; Cosmetics containing hyaluronic acid; Cleansing creams; Cleansing lotions; Oils for cleaning purposes; Sunscreen preparations; All the aforesaid goods other than shaving cosmetics, shaving preparations, pre-shave and aftershave preparations.
Hypodermic needles for injection; Injection instruments without needles; Injection needles; Injection needles for medical use; Needles for injections; Medical syringe needles; Needles for surgical purposes; Needles for medical purposes; Needles for medical use; Needle holders for surgical use; Suture materials; Suture materials for medical use.
Suture materials for medical use; Suture materials; Hypodermic needles for injection; Injection instruments without needles; Injection needles; Injection needles for medical use; Needles for injections; Medical syringe needles; Needles for surgical purposes; Needles for medical use; Needles for medical purposes; Needle holders for surgical use.
A sterile hydrogel composition comprising a crosslinked polymer, wherein the crosslinked polymer is an oxidation product of a thiol-modified hyaluronan and wherein the thiol- modified hyaluronan has a degree of modification of hyaluronan with thiol moietiesof more than about 80 µmol per gram polymer, wherein the thiol-modified hyaluronan has a degree of modification of hyaluronan with thiol moieties of less than about 280 µmol per gram polymer, and wherein the thiol-modified hyaluronan has a mean molecular weight of at least 400 kDa.
A sterile hydrogel composition comprising a crosslinked polymer, wherein the crosslinked polymer is an oxidation product of a thiol-modified hyaluronan and wherein the thiol- modified hyaluronan has a degree of modification of hyaluronan with thiol moietiesof more than about 80 µmol per gram polymer, wherein the thiol-modified hyaluronan has a degree of modification of hyaluronan with thiol moieties of less than about 280 µmol per gram polymer, and wherein the thiol-modified hyaluronan has a mean molecular weight of at least 400 kDa.
A sterile hydrogel composition comprising a crosslinked polymer, wherein the crosslinked polymer is an oxidation product of a thiol-modified hyaluronan and wherein the thiol-modified hyaluronan has a degree of modification of hyaluronan with thiol moieties of more than about 80 μmol per gram polymer, wherein the thiol-modified hyaluronan has a degree of modification of hyaluronan with thiol moieties of less than about 280 μmol per gram polymer, wherein the composition has a residual thiol content of less than 20% in respect to the degree of modification of the thiol-modified hyaluronan.
Sterile hydrogel composition comprising crosslinked hyaluronan, wherein the amount of extractable hyaluronan having a molecular weight of less than 200 kDa is less than 15 wt.% relative to the total amount of hyaluronan.
Sterile hydrogel composition comprising crosslinked hyaluronan, wherein the amount of extractable hyaluronan having a molecular weight of less than 200 kDa is less than 15 wt.% relative to the total amount of hyaluronan.
A sterile hydrogel composition comprising a crosslinked polymer, wherein the crosslinked polymer is an oxidation product of a thiol-modified hyaluronan and wherein the thiol-modified hyaluronan has a degree of modification of hyaluronan with thiol moieties of more than about 80 µmol per gram polymer, wherein the thiol-modified hyaluronan has a degree of modification of hyaluronan with thiol moieties of less than about 280 µmol per gram polymer, wherein the composition has a residual thiol content of less than 20% in respect to the degree of modification of the thiol-modified hyaluronan.
09 - Scientific and electric apparatus and instruments
35 - Advertising and business services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Computer programmes for data processing; assistive software;
data management software. Business administration. Software development, programming and implementation. Human hygiene and beauty care; professional consultancy
relating to health.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Advertising, marketing and promotion services; advertising
services relating to pharmaceutical products. Organisation of conferences, exhibitions and competitions;
arrangement of conferences for educational purposes;
arranging of seminars; conducting seminars; arranging of
educational conferences; arranging and conducting of
conferences. Pharmaceutical research services; medical research services;
clinical research; consultancy relating to research and
development in the field of therapeutics; research and
development for the pharmaceutical industry; services for
assessing the efficiency of pharmaceuticals; pharmaceutical
product evaluation; development of testing methods; product
testing; scientific laboratory services. Consultancy relating to health care; health care consultancy
services [medical]; health counseling; preparation of
reports relating to health care matters; consultancy in the
field of body and beauty care; cosmetic facial and body
treatment services; cosmetics consultancy services;
consultancy services relating to cosmetics; consultancy
relating to cosmetics; cosmetic treatment for the face.
The invention provides a hydrogen sulfide releasing polymer compound having a polysaccharide backbone, wherein the compound has at least two substructures, and wherein said substructures are capable of releasing hydrogen sulfide by thiol activation as well as uses thereof. Additionally, a method of treatment and prevention of a skin condition, an ocular disease or osteoarthritis is provided.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Advertising the goods and services of others; marketing and promoting the goods and services of others, namely, through product and sales demonstrations for others; advertising relating to pharmaceutical products of others.
(2) Organizing conferences, exhibitions and competitions in the fields of pharmaceuticals, skin care, cosmetic medicine, and aesthetic and beauty treatments; arranging conferences for educational purposes in the fields of pharmaceuticals, skin care, cosmetic medicine and aesthetic and beauty treatments; arranging of seminars in the fields of pharmaceuticals, skin care, cosmetic medicine and aesthetic and beauty treatments; conducting seminars in the fields of pharmaceuticals, skin care, cosmetic medicine and aesthetic and beauty treatments; arranging and conducting of conferences in the fields of pharmaceuticals, skin care, cosmetic medicine and aesthetic and beauty treatments.
(3) Pharmaceutical research services; medical research services; clinical research in the field of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; clinical research in the design, development and testing of prescription drugs and medical devices; consultancy relating to research and development in the field of therapeutics; research and development for the pharmaceutical industry; pharmaceutical product evaluation; development of testing and analysis methods in the fields of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; product testing, namely, design and development of testing and analysis methods in the fields of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; laboratory services, namely, laboratory testing in the fields of pharmaceuticals, cosmetic treatments, and dermatology; medical laboratory services; laboratory testing of pharmaceutical preparations, cosmetic treatment preparations and dermatological preparations; laboratory analysis in the field of cosmetics; laboratory research services in the fields of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; medical research laboratory services; laboratory research services relating to pharmaceuticals; laboratory research services relating to dermatology.
(4) Health care consultancy services, namely, consultancy in the fields of medical services, medical care and analysis services relating to patient treatment, medical laboratory services, cosmetic surgery, cosmetic body care and cosmetic treatment services; health care consultancy services, namely, consultancy in the fields of medical services, medical care and analysis services relating to patient treatment, medical laboratory services, cosmetic surgery, cosmetic body care and cosmetic treatment services; health counselling, namely, medical counselling in the fields of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; preparation of reports relating to health care matters; consultancy in the field of body and beauty care; cosmetic analysis; cosmetic facial and body treatment services; cosmetics consultancy services; consultancy services relating to cosmetics; consultancy relating to cosmetics; cosmetic treatment for the face.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Advertising, marketing and promotion services; advertising services relating to pharmaceutical products Organisation of educational conferences, educational exhibitions and organization of competitions in the field of aesthetic dermatological medicine; arrangement of conferences for educational purposes; arranging of seminars in the field of aesthetic dermatological medicine; conducting seminars in the field of aesthetic dermatological medicine; arranging of educational conferences; arranging and conducting of aesthetic dermatological medicine educational conferences Pharmaceutical research services; medical research services; clinical research in the field of aesthetic dermatological medicine; consultancy relating to research and development in the field of therapeutics; research and development for the pharmaceutical industry in the field of aesthetic dermatological medicine; services for assessing the efficiency of pharmaceuticals, namely, testing of pharmaceuticals; pharmaceutical product evaluation; development of testing methods of the effectiveness of aesthetic dermatological treatment; product testing; scientific laboratory services Consultancy relating to health care in the field of aesthetic dermatological medicine; health care consultancy services, namely, medical consultation and health counseling in the field of aesthetic dermatological medicine; health counseling; medical reporting services and medical information services, namely, preparation of reports relating to health care matters
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Cosmetics. Veterinary preparations; pharmaceutical preparations;
dietetic foods for medicinal purposes; nutritional additives
to foodstuffs for animals, for medical purposes. Surgical apparatus and instruments.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Cosmetics
(2) Veterinary preparations for intradermal, intraocular, intraarticular and ophthalmological surgery; Pharmaceutical preparations, namely viscoelastic preparations for intradermal, intraocular, intraarticular and ophthalmological applications; Dietetic foods for medicinal purposes, namely, dietary supplements for general health and well-being, botanical supplements for general health and well-being and herbal supplements for general health and well-being; Nutritional additives to foodstuffs for animals, for medical purposes.
(3) Surgical instruments; surgical apparatus, namely, needles for medical purposes, injection syringes and cannula.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Cosmetics Pharmaceutical preparations for treating intradermal, intraocular and ophtalmological conditions; pharmaceutical preparations for intradermal, intraocular and ophtalmological surgery; dietetic foods adapted for medicinal purposes; nutritional additives to foodstuffs for use as a nutritional supplement for animals, for medical purposes Surgical apparatus and instruments
The present invention relates to a sterile aqueous ophthalmic solution comprising N-(N-acetylcysteinyl-)chitosan with a content of free thiol groups of from 80 to 280 umol/g polymer, for use in the treatment of a non-infectious corneal disorder, in particular dry eye diseases and persistent corneal epithelial defects, wherein said solution is applied intermittently, characterised by a scheme of treatment wherein the solution is applied to the eye for a period A of 5 days or more, then the application is paused for a period B of at least 2 and at most 180 days and then applied again for a period C of 1 day or more.
A61K 47/61 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
The present invention relates to a sterile aqueous ophthalmic solution comprising N—(N-acetylcysteinyl-)chitosan or a pharmaceutically acceptable salt thereof in a carrier solution, wherein the N—(N-acetylcysteinyl-)chitosan has a content of free thiol groups in an amount of from 80 μmol/g polymer to 280 μmol/g polymer, for use in the treatment of corneal wounds.
The present invention relates to a sterile aqueous ophthalmic solution comprising N-(N-acetylcysteinyl-)chitosan or a pharmaceutically acceptable salt thereof in a carrier solution, wherein the N-(N-acetylcysteinyl-)chitosan has a content of free thiol groups in an amount of from 80 μmol/g polymer to 280 μmol/g polymer, for the specific use in the prevention or treatment of dry eye syndrome or dry eye signs and/or symptoms wherein said solution is applied prior to sleep.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Advertising, marketing and promotion services; Advertising services relating to pharmaceutical products. Organisation of conferences, exhibitions and competitions; Arrangement of conferences for educational purposes; Arranging of seminars; Conducting seminars; Arranging of educational conferences; Arranging and conducting of conferences. Pharmaceutical research services; Medical research services; Clinical research; Consultancy relating to research and development in the field of therapeutics; Research and development for the pharmaceutical industry; Services for assessing the efficiency of pharmaceuticals; Pharmaceutical product evaluation; Development of testing methods; Product testing; Laboratory services. Consultancy relating to health care; Health care consultancy services [medical]; Health counseling; Preparation of reports relating to health care matters; Consultancy in the field of body and beauty care; Cosmetic analysis; Cosmetic facial and body treatment services; Cosmetics consultancy services; Consultancy services relating to cosmetics; Consultancy relating to cosmetics; Cosmetic treatment for the face.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations for skin care; Acne treatment preparations; Pharmaceutical preparations; Chemical preparations for pharmaceutical purposes; Pharmaceuticals; Biological preparations for medical purposes; Chemical preparations for medical purposes.
Hypodermic needles for injection; injection instruments
without needles; injection needles; injection needles for
medical use; needles for injections; medical syringe
needles; needles for surgical purposes; needles for medical
purposes; needles for medical use; needle holders for
surgical use; suture materials; suture materials for medical
use.
The invention provides a hydrogen sulfide releasing polymer compound having a polysaccharide backbone, wherein the compound has at least two substructures, and wherein said substructures are capable of releasing hydrogen sulfide by thiol activation as well as uses thereof. Additionally, a method of treatment and prevention of a skin condition, an ocular disease or osteoarthritis is provided.
The present invention is concerned with a sterile aqueous ophthalmic solution comprising about 0.05% to about 0.5% (w/w) of N—(N-acetylcysteinyl-)chitosan or a pharmaceutically acceptable salt thereof in a carrier solution, wherein the N—(N-acetylcysteinyl-)chitosan has a content of free thiol groups in an amount of from 80 μmol/g polymer to 280 μmol/g polymer. The invention is also concerned with a container containing said ophthalmic solution as well as the use thereof in the prevention or treatment of dry eye syndrome or dry eye signs and/or symptoms.
A61K 31/715 - Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkagesDerivatives thereof, e.g. ethers, esters
A61K 47/61 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
B65D 81/26 - Adaptations for preventing deterioration or decay of contentsApplications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, fluids, e.g. exuded by contentsApplications of corrosion inhibitors or desiccators
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Cosmetics. Veterinary preparations; Pharmaceutical preparations; Dietetic foods for medicinal purposes; Nutritional additives to foodstuffs for animals, for medical purposes. Surgical apparatus and instruments.
Hypodermic needles for injection; Injection instruments without needles; Injection needles; Injection needles for medical use; Needles for injections; Medical syringe needles; Needles for surgical purposes; Needles for medical purposes; Needles for medical use; Needle holders for surgical use; Suture materials; Suture materials for medical use.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Marketing and promoting the goods and services of others, namely, through product and sales demonstrations for others; consulting services in the field of business advertising and marketing, advisory services in the fields of business advertising, business marketing.
(2) Arrangement of conferences for educational purposes in the fields of pharmaceuticals, skin care, cosmetic medicine, and aesthetic and beauty treatments; arranging and conducting conferences, seminars, conventions, symposiums, competitions, congresses, and exhibitions for educational purposes in the fields of pharmaceuticals, skin care, cosmetic medicine and aesthetic and beauty treatments.
(3) Medical and pharmacological research services; clinical research in the field of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; clinical research in the design, development and testing of prescription drugs and medical devices; biological research, namely, cosmetic research and pharmaceutical research services; providing medical and scientific research information in the field of pharmaceuticals and clinical trials; consultancy relating to research and development in the field of therapeutics in dermatology and aesthetic and skin care treatment, and cosmetic medicine; research and development for the pharmaceutical industry; services for assessing the efficiency of pharmaceuticals; pharmaceutical product evaluation; design and development of testing and analysis methods in the fields of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; laboratory testing in the fields of pharmaceuticals, cosmetic treatments, and dermatology; medical laboratory services; laboratory research services in the field of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; medical research laboratory services; laboratory research services relating to pharmaceuticals; laboratory research services relating to dermatology; testing of pharmaceutical preparations, cosmetic treatment preparations and dermatological preparations; design and development of testing and analysis methods for testing of pharmaceutical preparations, cosmetic treatment preparations and dermatological preparations for others to conducting similar tests; laboratory analysis in the field of cosmetics.
(4) Health care consultancy services, namely, consultancy in the fields of medical services, medical care and analysis services relating to patient treatment, medical laboratory services, cosmetic surgery, cosmetic body care and cosmetic treatment services; medical and healthcare services, namely, medical examination services, medical care and analysis services relating to patient treatment; preparation of reports relating to health care matters; consultancy services in the field of body and beauty care, namely, dermatology, aesthetic and skin care treatment, and cosmetic medicine; cosmetic analysis; consultation services relating to skin care; cosmetic facial and body treatment services; cosmetics consultancy services; consultancy services relating to cosmetics; cosmetic treatment for the face; advisory services in the fields of pharmaceuticals, skincare and cosmetic and aesthetic medicine.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Marketing and promoting the goods and services of others, namely, through product and sales demonstrations for others; consulting services in the field of business advertising and marketing, advisory services in the fields of business advertising, business marketing.
(2) Arrangement of conferences for educational purposes in the fields of pharmaceuticals, skin care, cosmetic medicine, and aesthetic and beauty treatments; arranging and conducting conferences, seminars, conventions, symposiums, competitions, congresses, and exhibitions for educational purposes in the fields of pharmaceuticals, skin care, cosmetic medicine and aesthetic and beauty treatments.
(3) Medical and pharmacological research services; clinical research in the field of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; clinical research in the design, development and testing of prescription drugs and medical devices; biological research, namely, cosmetic research and pharmaceutical research services; providing medical and scientific research information in the field of pharmaceuticals and clinical trials; consultancy relating to research and development in the field of therapeutics in dermatology and aesthetic and skin care treatment, and cosmetic medicine; research and development for the pharmaceutical industry; services for assessing the efficiency of pharmaceuticals; pharmaceutical product evaluation; design and development of testing and analysis methods in the fields of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; laboratory testing in the fields of pharmaceuticals, cosmetic treatments, and dermatology; medical laboratory services; laboratory research services in the field of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; medical research laboratory services; laboratory research services relating to pharmaceuticals; laboratory research services relating to dermatology; testing of pharmaceutical preparations, cosmetic treatment preparations and dermatological preparations; design and development of testing and analysis methods for testing of pharmaceutical preparations, cosmetic treatment preparations and dermatological preparations for others to conducting similar tests; laboratory analysis in the field of cosmetics.
(4) Health care consultancy services, namely, consultancy in the fields of medical services, medical care and analysis services relating to patient treatment, medical laboratory services, cosmetic surgery, cosmetic body care and cosmetic treatment services; medical and healthcare services, namely, medical examination services, medical care and analysis services relating to patient treatment; preparation of reports relating to health care matters; consultancy services in the field of body and beauty care, namely, dermatology, aesthetic and skin care treatment, and cosmetic medicine; cosmetic analysis; consultation services relating to skin care; cosmetic facial and body treatment services; cosmetics consultancy services; consultancy services relating to cosmetics; cosmetic treatment for the face; advisory services in the fields of pharmaceuticals, skincare and cosmetic and aesthetic medicine.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Marketing and promoting the goods and services of others, namely, through product and sales demonstrations for others; consulting services in the field of business advertising and marketing, advisory services in the fields of business advertising, business marketing.
(2) Arrangement of conferences for educational purposes in the fields of pharmaceuticals, skin care, cosmetic medicine, and aesthetic and beauty treatments; arranging and conducting conferences, seminars, conventions, symposiums, competitions, congresses, and exhibitions for educational purposes in the fields of pharmaceuticals, skin care, cosmetic medicine and aesthetic and beauty treatments.
(3) Medical and pharmacological research services; clinical research in the field of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; clinical research in the design, development and testing of prescription drugs and medical devices; biological research, namely, cosmetic research and pharmaceutical research services; providing medical and scientific research information in the field of pharmaceuticals and clinical trials; consultancy relating to research and development in the field of therapeutics in dermatology and aesthetic and skin care treatment, and cosmetic medicine; research and development for the pharmaceutical industry; services for assessing the efficiency of pharmaceuticals; pharmaceutical product evaluation; design and development of testing and analysis methods in the fields of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; laboratory testing in the fields of pharmaceuticals, cosmetic treatments, and dermatology; medical laboratory services; laboratory research services in the field of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; medical research laboratory services; laboratory research services relating to pharmaceuticals; laboratory research services relating to dermatology; testing of pharmaceutical preparations, cosmetic treatment preparations and dermatological preparations; design and development of testing and analysis methods for testing of pharmaceutical preparations, cosmetic treatment preparations and dermatological preparations for others to conducting similar tests; laboratory analysis in the field of cosmetics.
(4) Health care consultancy services, namely, consultancy in the fields of medical services, medical care and analysis services relating to patient treatment, medical laboratory services, cosmetic surgery, cosmetic body care and cosmetic treatment services; medical and healthcare services, namely, medical examination services, medical care and analysis services relating to patient treatment; preparation of reports relating to health care matters; consultancy services in the field of body and beauty care, namely, dermatology, aesthetic and skin care treatment, and cosmetic medicine; cosmetic analysis; consultation services relating to skin care; cosmetic facial and body treatment services; cosmetics consultancy services; consultancy services relating to cosmetics; cosmetic treatment for the face; advisory services in the fields of pharmaceuticals, skincare and cosmetic and aesthetic medicine.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Advertising, marketing and promotional services; Advertising, marketing and promotional consultancy, advisory and assistance services; Advertising services relating to pharmaceutical products. Arrangement of conferences for educational purposes; Arranging and conducting conferences and seminars; Arranging and conducting educational conferences; Arranging and conducting conferences; Arranging and conducting of conferences and congresses; Arranging and conducting of conferences, congresses and symposiums; Arranging and conducting of congresses; Congresses (Arranging and conducting of -); Arranging and conducting of conventions; Organisation of conferences, exhibitions and competitions. Medical and pharmacological research services; Clinical research; Biological research, clinical research and medical research; Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; Consultancy relating to research and development in the field of therapeutics; Research and development for the pharmaceutical industry; Services for assessing the efficiency of pharmaceuticals; Pharmaceutical product evaluation; Development of testing methods; Design and development of testing and analysis methods; Laboratory services; Laboratory testing services; Analytical laboratory services; Analytic laboratory services; Scientific laboratory services; Medical laboratory services; Research laboratory services; Medical research laboratory services; Laboratory research services relating to pharmaceuticals; Laboratory research services relating to dermatology; Product testing; Laboratory analysis in the field of cosmetics. Health care consultancy services [medical]; Medical and healthcare services; Professional consultancy relating to health care; Preparation of reports relating to health care matters; Consultancy in the field of body and beauty care; Cosmetic analysis; Consultation services relating to skin care; Cosmetic facial and body treatment services; Cosmetics consultancy services; Consultancy services relating to cosmetics; Cosmetic treatment for the face; Health counselling; Consulting services relating to health care.
67.
THERAPEUTIC USE OF A STERILE AQUEOUS OPHTHALMIC SOLUTION
The present invention relates to a sterile aqueous ophthalmic solution comprising N-(N-acetylcysteinyl-)chitosan or a pharmaceutically acceptable salt thereof in a carrier solution, wherein the N-(N-acetylcysteinyl-)chitosan has a content of free thiol groups in an amount of from 80 µmol/g polymer to 280 µmol/g polymer, for use in the treatment of corneal wounds.
The present invention relates to a sterile aqueous ophthalmic solution comprising N-(N- acetylcysteinyl-)chitosan or a pharmaceutically acceptable salt thereof in a carrier solution, wherein the N-(N-acetylcysteinyl-)chitosan has a content of free thiol groups in an amount of from 80 μmol/g polymer to 280 μmol/g polymer, for the specific use in the prevention or treatment of dry eye syndrome or dry eye signs and/or symptoms wherein said solution is applied prior to sleep.
The present invention relates to a sterile aqueous ophthalmic solution comprising N-(N-acetylcysteinyl-)chitosan or a pharmaceutically acceptable salt thereof in a carrier solution, wherein the N-(N-acetylcysteinyl-)chitosan has a content of free thiol groups in an amount of from 80 μmol/g polymer to 280 μmol/g polymer, for use in the treatment of corneal wounds.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Marketing and promoting the goods and services of others, namely, through product and sales demonstrations for others; consulting services in the field of business advertising and marketing, advisory services in the fields of business advertising, business marketing.
(2) Arrangement of conferences for educational purposes in the fields of pharmaceuticals, skin care, cosmetic medicine, and aesthetic and beauty treatments; arranging and conducting conferences, seminars, conventions, symposiums, competitions, congresses, and exhibitions for educational purposes in the fields of pharmaceuticals, skin care, cosmetic medicine and aesthetic and beauty treatments.
(3) Medical and pharmacological research services; clinical research in the field of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; clinical research in the design, development and testing of prescription drugs and medical devices; biological research, namely, cosmetic research and pharmaceutical research services; providing medical and scientific research information in the field of pharmaceuticals and clinical trials; consultancy relating to research and development in the field of therapeutics in dermatology and aesthetic and skin care treatment, and cosmetic medicine; research and development for the pharmaceutical industry; services for assessing the efficiency of pharmaceuticals; pharmaceutical product evaluation; design and development of testing and analysis methods in the fields of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; laboratory testing in the fields of pharmaceuticals, cosmetic treatments, and dermatology; medical laboratory services; laboratory research services in the field of pharmaceuticals, dermatology and aesthetic and skin care treatment, and cosmetic medicine; medical research laboratory services; laboratory research services relating to pharmaceuticals; laboratory research services relating to dermatology; testing of pharmaceutical preparations, cosmetic treatment preparations and dermatological preparations; design and development of testing and analysis methods for testing of pharmaceutical preparations, cosmetic treatment preparations and dermatological preparations for others to conducting similar tests; laboratory analysis in the field of cosmetics.
(4) Health care consultancy services, namely, consultancy in the fields of medical services, medical care and analysis services relating to patient treatment, medical laboratory services, cosmetic surgery, cosmetic body care and cosmetic treatment services; medical and healthcare services, namely, medical examination services, medical care and analysis services relating to patient treatment; preparation of reports relating to health care matters; consultancy services in the field of body and beauty care, namely, dermatology, aesthetic and skin care treatment, and cosmetic medicine; cosmetic analysis; consultation services relating to skin care; cosmetic facial and body treatment services; cosmetics consultancy services; consultancy services relating to cosmetics; cosmetic treatment for the face; advisory services in the fields of pharmaceuticals, skincare and cosmetic and aesthetic medicine.
71.
CROMA Asian Faces - NLF Severity Rating Scale (NLFA-SRS)
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Advertising, marketing and promotional services; Advertising, marketing and promotional consultancy, advisory and assistance services; Advertising services relating to pharmaceutical products. Arrangement of conferences for educational purposes; Arranging and conducting conferences and seminars; Arranging and conducting educational conferences; Arranging and conducting conferences; Arranging and conducting of conferences and congresses; Arranging and conducting of conferences, congresses and symposiums; Arranging and conducting of congresses; Congresses (Arranging and conducting of -); Arranging and conducting of conventions; Organisation of conferences, exhibitions and competitions. Medical and pharmacological research services; Clinical research; Biological research, clinical research and medical research; Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; Consultancy relating to research and development in the field of therapeutics; Research and development for the pharmaceutical industry; Services for assessing the efficiency of pharmaceuticals; Pharmaceutical product evaluation; Development of testing methods; Design and development of testing and analysis methods; Laboratory services; Laboratory testing services; Analytical laboratory services; Analytic laboratory services; Scientific laboratory services; Medical laboratory services; Research laboratory services; Medical research laboratory services; Laboratory research services relating to pharmaceuticals; Laboratory research services relating to dermatology; Product testing; Laboratory analysis in the field of cosmetics. Health care consultancy services [medical]; Medical and healthcare services; Professional consultancy relating to health care; Preparation of reports relating to health care matters; Consultancy in the field of body and beauty care; Cosmetic analysis; Consultation services relating to skin care; Cosmetic facial and body treatment services; Cosmetics consultancy services; Consultancy services relating to cosmetics; Cosmetic treatment for the face; Health counselling; Consulting services relating to health care.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Advertising, marketing and promotional services; Advertising, marketing and promotional consultancy, advisory and assistance services; Advertising services relating to pharmaceutical products. Arrangement of conferences for educational purposes; Arranging and conducting conferences and seminars; Arranging and conducting educational conferences; Arranging and conducting of conferences; Arranging and conducting of conferences and congresses; Arranging and conducting of congresses; Arranging and conducting of conventions; Arranging and conducting of conferences, congresses and symposiums; Organisation of conferences, exhibitions and competitions. Medical and pharmacological research services; Clinical research; Biological research, clinical research and medical research; Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; Consultancy relating to research and development in the field of therapeutics; Research and development for the pharmaceutical industry; Services for assessing the efficiency of pharmaceuticals; Pharmaceutical product evaluation; Development of testing methods; Design and development of testing and analysis methods; Laboratory services; Laboratory testing services; Analytic laboratory services; Scientific laboratory services; Medical laboratory services; Medical research laboratory services; Product testing; Laboratory analysis in the field of cosmetics. Consulting services relating to health care; Health care consultancy services [medical]; Medical and healthcare services; Professional consultancy relating to health care; Preparation of reports relating to health care matters; Consultancy in the field of body and beauty care; Cosmetic analysis; Consultation services relating to skin care; Cosmetic facial and body treatment services; Cosmetics consultancy services; Consultancy services relating to cosmetics; Cosmetic treatment for the face; Health counseling.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Advertising, marketing and promotional services; Advertising, marketing and promotional consultancy, advisory and assistance services; Advertising services relating to pharmaceutical products. Arrangement of conferences for educational purposes; Arranging and conducting conferences and seminars; Arranging and conducting educational conferences; Arranging and conducting of conferences; Arranging and conducting of conferences and congresses; Arranging and conducting of congresses; Arranging and conducting of conventions; Arranging and conducting of conferences, congresses and symposiums; Organisation of conferences, exhibitions and competitions. Medical and pharmacological research services; Clinical research; Biological research, clinical research and medical research; Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; Consultancy relating to research and development in the field of therapeutics; Research and development for the pharmaceutical industry; Services for assessing the efficiency of pharmaceuticals; Pharmaceutical product evaluation; Development of testing methods; Design and development of testing and analysis methods; Laboratory services; Laboratory testing services; Analytic laboratory services; Scientific laboratory services; Medical laboratory services; Medical research laboratory services; Product testing; Laboratory analysis in the field of cosmetics. Consulting services relating to health care; Health care consultancy services [medical]; Medical and healthcare services; Professional consultancy relating to health care; Preparation of reports relating to health care matters; Consultancy in the field of body and beauty care; Cosmetic analysis; Consultation services relating to skin care; Cosmetic facial and body treatment services; Cosmetics consultancy services; Consultancy services relating to cosmetics; Cosmetic treatment for the face; Health counseling.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
Goods & Services
Preparations for body and beauty care, namely cosmetic skin
and face masks with rejuvenating, refreshing and/or firming
effect, rejuvenating, volumizing lip care products with
anti-aging, nourishing, moisturizing, smoothing and/or
contouring effect, individualized and personalized skincare
products, skincare products with whitening, brightening
effect, skincare products with a cleaning effect, individual
DNA customized skincare products; solutions and cosmetics
for meso-therapeutic purposes; custom-made facial and body
creams, rejuvenating, nourishing and moisturizing anti-aging
creams for face and body, cosmetic creams and serums with
anti-aging effect and soothing, irritation reducing
toiletries.
75.
AQUEOUS OPHTHALMIC SOLUTION AND METHOD FOR TREATING DRY EYE SYNDROME
The present invention is concerned with a sterile aqueous ophthalmic solution comprising about 0.05% to about 0.5% (w/w) of N-(N-acetylcysteinyl-)chitosan or a pharmaceutically acceptable salt thereof in a carrier solution, wherein the N-(N-acetylcysteinyl-)chitosan has a content of free thiol groups in an amount of from 80 µmol/g polymer to 280 µmol/g polymer. The invention is also concerned with a container containing said ophthalmic solution as well as the use thereof in the prevention or treatment of dry eye syndrome or dry eye signs and/or symptoms.
The present invention is concerned with a sterile aqueous ophthalmic solution comprising about 0.05% to about 0.5% (w/w) of N-(N-acetylcysteinyl-)chitosan or a pharmaceutically acceptable salt thereof in a carrier solution, wherein the N-(N-acetylcysteinyl-)chitosan has a content of free thiol groups in an amount of from 80 μmol/g polymer to 280 μmol/g polymer. The invention is also concerned with a container containing said ophthalmic solution as well as the use thereof in the prevention or treatment of dry eye syndrome or dry eye signs and/or symptoms.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
77.
Mucoadhesive polymers having vitamin B partial structures
Because of the formation of disulfide bridges with mucus glycoproteins, the mucoadhesive properties of polymeric compounds can be significantly improved by the covalent attachment of thiol substructures to them. By the transformation of free thiol groups on such polymers in disulfides with mercaptonicotinamides or mercaptopyridoxins these thiol groups become comparatively more reactive resulting in significantly improved mucoadhesive properties. Furthermore, polymers exhibiting disulfide partial structures with mercaptonicotinamides or mercaptopyridoxins do not need to be protected against oxidation. In addition, they show comparatively higher permeation enhancing properties.
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 47/58 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
A61K 47/61 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
A61Q 5/06 - Preparations for styling the hair, e.g. by temporary shaping or colouring
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
pharmaceutical products for intradermal use surgical and medical instruments, namely, injection needles, syringes and absorbable threads for use in dermatology
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
Goods & Services
(1) Cosmetics, masks, creams and lotions for moisturizing and firming the skin and prevention of wrinkles; cosmetics; cosmetic facial lotions; skin care lotions [cosmetic]; skin masks [cosmetics]; non-medicated skin cleansing creams; face creams for cosmetic use; non-medicated skin creams; creams for firming the skin; anti-wrinkle cream; cosmetics in the form of creams.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Pharmaceutical products for aesthetic treatments, namely, injectables for intradermal and subcutaneous application for facial and body skin tightening and smoothing, preparations for cosmetic conditions, namely for the treatment of skin conditions, namely, dryness and signs of aging; surgical and medical instruments, namely needles, syringes and cannula for use in dermatology; dermatological pharmaceutical products, namely, medicated preparations for the treatment of the skin, namely, for the treatment of ptosis, dermatitis, skin pigmentation diseases and the treatment of skin irritations, namely, bee stings, sunburns, rashes, sores, corns, calluses and acne; topical anaesthetics; topical gels for treatment of scars; suture needles; needles for surgical purposes; needles for medical purposes; hypodermic needles; hypodermic needles for injection.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Dermatological pharmaceutical products; Parapharmaceutical products for use in dermatology. Suture needles; Needles for surgical purposes; Needles for medical purposes; Hypodermic needles; Hypodermic needles for injection.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Dermatological pharmaceutical products; Pharmaceutical preparations for use in dermatology. Hypodermic needles for injection; Injection instruments without needles; Injection needles; Injection needles for medical use; Needles for injections; Medical syringe needles; Needles for surgical purposes; Needles for medical purposes; Needles for medical use; Needle holders for surgical use; Suture materials; Suture materials for medical use.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Cosmetics pharmaceutical and veterinary preparations for treating diseases in the fields of dermatology, ophthalmology, and orthopaedics, and for pain treatment; dietetic foods, namely, pasta and crackers adapted for medical use, synthetically derived food additives for medical purposes being nutritional supplements, and nutritional food additives for medical purposes in the nature of natural food extracts derived from vegetables, fish, meat Surgical apparatus and instruments
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Cosmetics; pharmaceutical preparations for ocular and intraocular surgery, pharmaceutical preparations for the treatment of glaucoma, pharmaceutical preparations for the treatment of infectious diseases, namely, respiratory infections, eye infections, pharmaceutical preparations for the treatment of ophthalmologic diseases and disorders, pharmaceutical preparations for use in ocular disorders, pharmaceutical preparations for use in oncology, pharmaceutical preparations for use in ophthalmology, pharmaceutical preparations for ophthalmologic use; dietary supplements for general health and well-being, mineral supplements, vitamin supplements; nutritional supplements for general health and well-being; surgical instruments; surgical instruments for ophthalmologic surgery; surgical instruments for orthopaedic surgery; surgical instruments for plastic surgery.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Pharmaceutical and veterinary preparations; sanitary
preparations for medical purposes; dietetic food and
substances adapted for medical or veterinary use, food for
babies; dietary supplements for humans and animals;
plasters, materials for dressings; material for stopping
teeth, dental wax; disinfectants; preparations for
destroying vermin; fungicides, herbicides. Surgical, medical, dental and veterinary apparatus and
instruments, artificial limbs, eyes and teeth; orthopedic
articles; suture materials.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Pharmaceutical and veterinary preparations; Sanitary preparations for medical purposes; Dietetic food and substances adapted for medical or veterinary use, food for babies; Dietary supplements for humans and animals; Plasters, materials for dressings; Material for stopping teeth, dental wax; Disinfectants; Preparations for destroying vermin; Fungicides, herbicides. Surgical, medical, dental and veterinary apparatus and instruments, artificial limbs, eyes and teeth; Orthopedic articles; Suture materials.
The invention is a method of designing a toric intraocular lens that provides a level of tolerance to axis alignment error so that the negative aspects of an axis alignment error are mitigated creating a tolerant toric intraocular lens. Advantages of this invention will become apparent from the following description taken in conjunction with any accompanying drawings wherein are set forth, by way of illustration and example, contain embodiments of this invention.
The invention relates to the use of an aqueous viscoelastic fluids for producing a medicinal product for surgically treating the eye, said fluid enlarging the crystalline lens and pupil of the eye after being applied to the eye surface from a disposable container. Said viscoelastic fluid contains a polymer selected from the group consisting of hydroxypropyl methylcellulose, carboxymethyl cellulose, hydroxyethylcellulose, hyaluronic acid, sodium alginate, hydroxylpropyl-guar polyvinylpyrrolidone, polyvinyl alcohol, polymethacrylic acid (carbomer), polyoxyethylene-polyoxypropylene-copolymer (poloxamer) and polyethylene glycol, in a concentration of between 0,01-30%.
Because of the formation of disulfide bridges with mucus glycoproteins, the mucoadhesive properties of polymeric compounds can be significantly improved by the covalent attachment of thiol substructures to them. By the transformation of free thiol groups on such polymers in disulfides with mercaptonicotinamides or mercaptopyridoxins these thiol groups become comparatively more reactive resulting in significantly improved mucoadhesive properties. Furthermore, polymers exhibiting disulfide partial structures with mercaptonicotinamides or mercaptopyridoxins do not need to be protected against oxidation. In addition, they show comparatively higher permeation enhancing properties.
A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
Pharmaceutical preparation for intraarticular injection for treating inflammatory and degenerative joint disorders containing 0.2-32% (m/v) dextran with an average molecular weight of 500 to 3,000 Da and 0.1-10% sodium hyaluronate with an average molecular weight of 500,000 to 3500,000 Da, with the proviso that no further dextran having an average molecular weight in the range of 30,000 and 110,000 Da is contained.
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Cosmetics; pharmaceutical preparations, namely, for the treatment of ophthalmological and orthopedic diseases and disorders, viscoelastic solutions filled in syringes used during cataract surgery, intraocular lenses used to replace the natural lens during cataract surgery, viscoelastic solutions filled in syringes namely intradermal fillers in order to correct wrinkles and folds in the facial area, viscoelastic solutions filled in syringes for the injection into synovial joints during the course of arthritis; dietetic foods, namely, dietary supplements for general health and well-being, botanical supplements for general health and well-being, herbal supplements for general health and well-being, nutritional additives for medical purposes, namely, nutritional supplements for general health and well-being, vitamins; surgical apparatus and instruments, namely, surgical knives and scissors, cannulae, and machines used in ophthalmic and cataract surgery.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Intradermal products, namely, skin, wrinkle, line and scar filler, namely, viscoelastic substance used to alleviate and soften skin, wrinkles, lines and scars, lip enhancers, namely, viscoelastic substance for injection to increase the volume of the lips, lip care preparations.
(2) Surgical instruments and suture material.
99.
MUCOADHESIVE POLYMERS HAVING VITAMINE B PARTIAL STRUCTURES
Because of the formation of disulfide bridges with mucus glycoproteins, the mucoadhesive properties of polymeric compounds can. be significantly improved by the covalent attachment of thiol substructures to them. By the transformation of free thiol groups on such polymers in disulfides with mercaptonicotinamides or mercaptopyridoxins these thiol groups become comparatively more reactive resulting in significantly improved mucoadhesive properties. Furthermore, polymers exhibiting disulfide partialstructures with mercaptonicotinamides or mercaptopyridoxins do not need to be protected against oxidation. In addition, they show comparatively higher permeation enhancing properties.
THIOMATRIX FORSCHUNGS- UND BERATUNGS GMBH (Austria)
CROMA PHARMA GMBH (Austria)
Inventor
Leierer, Johannes
Abstract
The mucoadhesive properties of polymer compounds can be considerably improved by the covalent binding of thiol partial structures to said compounds, because as a result disulfide bridge bonds are formed having mucus glycoproteins. By converting the free thiol groups on such polymers into disulfides having mercaptonicotin amides or mercaptopyridoxines, said thiol groups become comparatively more reactive, so that the mucoadhesive properties of said polymers are considerably higher. In addition, polymers that comprise the disulfide partial structures having mercaptonicotin amides or mercaptopyridoxines do not have to be protected from oxidation and have comparatively higher permeation-accelerating properties.
A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
A61K 9/00 - Medicinal preparations characterised by special physical form
