Abstract

The present invention relates to ternary metal(s) hydroxide [(M1-M2-Ni)](OH)2] composite supported on nickel foam (NF) having nanoflower arrays structure, which acts as a self-standing bifunctional electrocatalyst for cathode as well as anode (both electrodes) for water electrolysis/splitting. Further, the present invention provides hydrothermal process for the preparation of said bi-functional electrocatalyst. The bifunctional catalyst disclosed herein is useful in performing water electrolysis reactions to generate hydrogen and oxygen.

IPC Classes  ?

• C25B 11/091 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds
• C23C 18/12 - Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coatingContact plating by thermal decomposition characterised by the deposition of inorganic material other than metallic material
• C25B 9/17 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof
• C25B 11/031 - Porous electrodes
• C25B 11/052 - Electrodes comprising one or more electrocatalytic coatings on a substrate
• C25B 11/061 - Metal or alloy

Abstract

Transition metal complexes as catalysts and, occasionally, basic pH 9-11 as a reaction condition were employed to imitate the catecholase activity. Using base as a catalyst, under photo- mediated condition the catalytic aerobic oxidation of the proxy substrate 3,5-di-tert- butylcatechol (DTBC) in polar protic solvent very fast was shown in this invention to be a functional mimic of catecholase activity. The Michaelis-Menten kinetic model's enzymatic substrate inhibition pattern was used to describe the kinetic manifestation of 3,5-di-tert- butylcatechol (DTBC) oxidation. Under photo-mediated condition the oxidation of 3,5-di-tert- butylcatechol (DTBC) was observed very fast which may be due to the higher energy increases the activation energy and under basic pH condition catechol oxidizes to 3,5-di-tert- butylcyclohexa-3,5-diene-1,2-dione (DTBQ).

IPC Classes  ?

• C07C 46/06 - Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
• C07C 46/02 - Preparation of quinones by oxidation giving rise to quinoid structures
• C07C 39/08 - Dihydroxy benzenesAlkylated derivatives thereof

Abstract

The present invention relates to process for preparation of green plasticizer Di-Octyl Terephthalate (DOTP) from polyethylene terephthalate (PET) post-consumer plastics waste through mechanically assisted degrative transesterification. More particularly, the present invention relates to continuous process for preparation of Di-Octyl Terephthalate using mechano-chemical assisted degradative transesterification of post consumed PET bottles. The mechanically assisted depolymerization under elevated pressure provides milling-assisted depolymerization under elevated pressure with the mass ratio of the PET to the secondary alcohol 1:3-4, temperature in the range of 200 to 220°C, and reaction time in the range of 3 to 4 hours, the degradation rate of the PET can reach 100 %, and the yield of the DOTP reaches to upto 90%. The process has the characteristics of a fast reaction rate, avoiding the formation of side chain oligomers and thereby attaining a high diester yield.

IPC Classes  ?

• B01J 9/18 -

Abstract

The present invention relates to an loT -enabled, solar-powered Atmospheric Water Generator (AWG) designed to provide potable water in arid, hilly, and water-scarce regions. The system further comprises closed-loop regulation of compressor operation based on calculated dew point derived from sensed ambient temperature and humidity, and independent fan control using a variable frequency drive (VFD) to optimize condensation efficiency. The system integrates UV sterilization, ozone dosing, and loT-based multi¬ parameter monitoring to ensure water quality and system performance. With zero water waste and no reliance on groundwater, this eco-friendly solution offers a sustainable alternative for water-scarce regions, providing clean, mineral -enriched drinking water that meets BIS standards. The AWG is particularly suited for drought-prone areas, coastal zones, and military applications.

IPC Classes  ?

• F24F 3/14 - Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatmentApparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling by humidificationAir-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatmentApparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling by dehumidification
• E03B 3/28 - Methods or installations for obtaining or collecting drinking water or tap water from humid air
• B01D 5/00 - Condensation of vapoursRecovering volatile solvents by condensation

Abstract

Antigens from multiple sources is a promising strategy to effectively stimulate all immuno-phenotypic sections of a diverse population. Therefore, combination of multiple protective antigens is a rationale strategy to boost immunogenicity of the vaccine designed for immunization in heterogeneous population as well as to use in effective diagnosis in all endemic areas. The strategy to combine antigens isisis to construct a fusion chimeric multivalent antigen. The present invention relates to the diagnostic and vaccine potential of a recombinant multiantigenic T cell epitope enriched fusion protein comprising of three Leishmania donovani proteins, glycoprotein 63 (GP63), elongation factor 1 α (EF1-α) and cysteine protease C (CPC) against visceral leishmaniasis. The said invention in particular relates to designing, cloning and purification of a novel T cell enriched multiantigenic recombinant protein for detection of Leishmania infection in the form of antigen-specific antibodies in the biological samples such as serum and urine.

IPC Classes  ?

• A61K 39/008 - Leishmania antigens
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/1277 - Preparation processesProliposomes
• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61P 33/02 - Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
• C07K 14/44 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from protozoa
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression
• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor

Abstract

The present invention provides a topical composition comprising gymnemic acids of (Formula I) or enriched gymnemic acid extract of Gymnema sylvestre for the treatment of various skin conditions such as diabetic ulcers, venous ulcers, pressure ulcers, burn wounds, psoriasis, acne, skin itching, cracked heels, and fissures. The formulation is effective in promoting wound healing, reducing inflammation, and alleviating symptoms associated with these conditions. The invention also provides the methods of using gymnemic acid-based compositions.

IPC Classes  ?

• A61K 8/9789 - Magnoliopsida [dicotyledons]
• A61K 8/92 - Oils, fats or waxesDerivatives thereof, e.g. hydrogenation products
• A61Q 19/00 - Preparations for care of the skin
• A61K 36/185 - Magnoliopsida (dicotyledons)
• A61K 36/24 - Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
• A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin

Abstract

The invention relates to a esterification of 2-ethoxyethanol with acetic acid in presence of ion exchange resin as a catalyst and an entrainer through reactive distillation method, which maintains the equilibrium of the reaction by continuously removing water (by-products) making it feasible at commercial level.

IPC Classes  ?

• C07C 67/08 - Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
• C07C 29/80 - SeparationPurificationStabilisationUse of additives by physical treatment by distillation
• C07C 29/12 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of esters of mineral acids
• C07B 61/00 - Other general methods

Abstract

The invention relates to chiral amino acids as well as symmetrical diamino triazine substituted phthalazinones as Poly(ADP-ribose)polymerase (PARP) Inhibitors, process for the preparation and uses thereof as potential 5 anticancer agents. The invention particularly relates to a process for the preparation of symmetrical for new. The compounds inhibited the growth and development of BRCA2 mutant cells with an IC50 value of the most active compounds in the range of 2-57 nM. The active compounds selectively induce cytotoxicity in BRCA2 mutant cancer cells compared to wild type cells with a mutant fold selectivity in range of 112- 2500-fold. The active compounds are capable of killing the BRCA mutated cancerous cells and show significant PARP 10 activity as well as show low cytotoxicity to wild type cells. Most importantly, our hit molecules demonstrated approximately 50% or greater cell viability of mice HSPCs. This suggests an improved hematological safety profile of our hits, distinguishing them from FDA-approved PARP inhibitor Olaparib.

IPC Classes  ?

• C07D 237/32 - Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
• C07D 251/40 - Nitrogen atoms
• C07D 241/04 - Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
• A61K 31/502 - PyridazinesHydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
• A61P 35/00 - Antineoplastic agents

Abstract

The present invention relates to a mutant LC3B allosteric switch, wherein three specific residues have been mutated to either reduce or enhance receptor binding, compared to the wild- type protein. In particular, the present invention provides a method for generating conformational ensemble of lipidated protein on the membrane and introducing specific mutations within the protein activation switch that is indirectly altering protein binding pocket without disrupting its functional domains. The identification of an activation site opens avenues for the development of small molecules or peptides to enhance or regulate protein activity, providing a new dimension for therapeutic interventions. Therefore, by linking the structural insights of lipidated forms to functional outcomes, the invention advances knowledge on LC3 activity regulation, which could further be utilized to modulate the autophagy pathways.

IPC Classes  ?

• C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
• C12N 15/12 - Genes encoding animal proteins
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression
• C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61P 35/00 - Antineoplastic agents

Abstract

Thermally activated delayed fluorescent solvent-free organic liquid compounds having formula (I) exhibits thermally activated delayed fluorescence properties for tunable emission and 3D-printing applications. Methods for preparing the compounds of formula (I) include reacting a brominated compound with a reactant in a reaction mixture including a base, a solvent, and optionally a catalyst and an additional ingredient at 100° C. to 150° C. for 9 hours to 28 hours. Thermally activated delayed fluorescent solvent-free organic liquid compounds having formula (I) exhibits thermally activated delayed fluorescence properties for tunable emission and 3D-printing applications. Methods for preparing the compounds of formula (I) include reacting a brominated compound with a reactant in a reaction mixture including a base, a solvent, and optionally a catalyst and an additional ingredient at 100° C. to 150° C. for 9 hours to 28 hours.

IPC Classes  ?

• C07F 5/04 - Esters of boric acids
• C07D 221/06 - Ring systems of three rings
• C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
• C07D 417/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

This study presents the synthesis of novel Benzodiazocine analogues and their potential as potent antiviral agents. Benzodiazocines, featuring an eight-membered fused bicyclic core, adhere to Lipinski's rule of five, ensuring drug-like properties. Structural modifications via Structure-Activity Relationship (SAR) enhanced their antiviral efficacy. In vitro assays, including cytotoxicity analysis and RT-qPCR-based studies, evaluated activity against SARS- CoV-2. Several analogues demonstrated promising antiviral potential, contributing to the ongoing pursuit of effective therapeutics against viral infections.

IPC Classes  ?

• C07D 245/06 - Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems condensed with one six-membered ring
• C07D 487/04 - Ortho-condensed systems
• A61K 31/395 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
• A61P 31/12 - Antivirals

Abstract

This invention provides a novel expedient one step synthetic procedure for the preparation of derivatives of dehydrocostus lactone and costunolide using diverse piperazine under very mild reaction condition and short period of time. The synthesized derivatives have improved safety profile along with anti-leishmanial killing potential. The potent leads displayed significant leishmanicidal potency and satisfactory selectivity against major macrophage cell lines (J774.A1 and RAW 264.7). Further, ex vivo analysis validated their potential for the clearance of intracellular amastigote burden with a better anti-amastigote selectivity index. The potent hits 1po and 2pp caused alteration in structural morphology, intracellular ROS generations, depletion in ATP pool indicating mitochondrial disfunction, accumulation of lipid inclusions, and disruption of sterol membrane. This study confirmed efficacy of synthesised derivatives against L. donovani supported by exploration of mechanistic insight. Further exploration of potent derivatives may lead to development of novel drug candidates to fight against parasitic infections.

IPC Classes  ?

• C07D 307/77 - Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
• C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
• C07D 241/04 - Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 31/495 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
• A61P 35/00 - Antineoplastic agents

Abstract

The present invention relates to development of novel ssDNA aptamers comprising the oligonucleotide sequence that detect receptor-binding domain (RBD) of Severe Acute Respiratory Syndrome Corona virus (SARS-nCOV-2) infection. The ssDNA aptamers of the present invention may be used in lateral flow assays, electrochemical sensors and calorimetric sensors using gold nanoparticles. The present invention also relates to an analytical composition comprising said ssDNA aptamers. Further, the present invention also relates to a diagnostic kit for detecting RBD of SARS-nCoV-2.

IPC Classes  ?

• G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
• C12N 1/20 - BacteriaCulture media therefor
• C12N 15/115 - Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12R 1/19 - Escherichia coli
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

The present invention relates to a method of in-vitro detoxification of multiple mycotoxins using Lactococcus lactis subsp. lactis which is isolated from traditional milk samples. The mycotoxins as disclosed in the present invention are ochratoxin A (OTA), zearalenone (ZEA), fumonisins B1 (FB1), deoxynivalenol (DON) and citrinin (CIT). In one aspect present invention relates to process of inactivation of spore germination and inhibition of biosynthesis of fumonisin B1 micotoxin using Lactococcus lactis subsp. lactis. The species Lactococcus lactis subsp. lactis produces novel antimicrobial metabolites such as 2,4-diotert-butylphenol, Pyrazinamide, and 3-5-dihydroxy-6-methyl-2,3-dihydro-4H-pyran-4-one.

IPC Classes  ?

• A23L 5/20 - Removal of unwanted matter, e.g. deodorisation or detoxification
• A23B 2/783 - MicroorganismsEnzymes
• C12N 1/205 -
• C12R 1/46 - Streptococcus

Abstract

The present invention provides a continuous mechano-chemical synchronization process designed to enhance the yield of acid hydrolysis of cellulose, specifically targeting the production of nanocrystalline cellulose (NCC). The process employs a two-stage controlled acid hydrolysis of Micro Crystalline Cellulose (MCC), utilizing a uniquely tailored reactor configuration to control morphology and optimize process efficiency. Additionally, it outlines advanced downstream operations for product neutralization and purification through tubular centrifuge and nano-pores membranes. The present invention also explores the potential for resource recovery for sustainability approach in this extraction process and demonstrates applications on biodegradable packaging, reinforced plastics and as absorbent materials for hygiene products.

IPC Classes  ?

• C08B 15/02 - OxycelluloseHydrocelluloseCellulose hydrate
• C08B 15/08 - Fractionation of cellulose, e.g. separation of cellulose crystallites
• C08L 1/04 - OxycelluloseHydrocellulose
• C08F 251/02 - Macromolecular compounds obtained by polymerising monomers on to polysaccharides or derivatives thereof on to cellulose or derivatives thereof
• B82Y 40/00 - Manufacture or treatment of nanostructures

Abstract

255 based multicolored electrochromic films with polyaniline (PANI) and NiO and device fabrication thereof. More particularly, present invention provides two-way modification of the base metal oxide by co¬ incorporation of a metal cation and a conjugated polymer, which resulted into an excellent improvement in the optical contrast, switching response and cyclic stability of the electrochromic device fabricated thereof.

IPC Classes  ?

• C03C 17/32 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating with organic material with synthetic or natural resins
• C01G 31/02 - Oxides
• G02F 1/155 - Electrodes
• G02F 1/15 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on an electrochromic effect
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01G 11/56 - Solid electrolytes, e.g. gelsAdditives therein

Abstract

The present invention discloses a microwave-assisted process for preparation of lead-free Mn-doped CsBr [Mn2+3532322322322322) in a mole ratio of 1:7 gives 1D CsMnBr3 nanocrystal.

IPC Classes  ?

• C01G 45/20 - Compounds containing manganese, with or without oxygen or hydrogen, and containing one or more other elements
• C01G 1/06 - Halides
• C09K 11/57 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing manganese or rhenium
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites

Abstract

The present invention relates to 5,6-diaryl-5,6-diazaspiro [2.4]heptane-4,7-dione compound of formula (I) and the process of preparation thereof. The present invention also relates to the compound of formula (I) and its use in the preparation of sulfinpyrazone uricosuric drug or its derivatives/analogues. The compound of formula (I) is useful as anti-malarial, anti-microbial, anti-bacterial, anti-inflammatory, COX-2 inhibition, and anti-analgesics agents. The present invention relates to 5,6-diaryl-5,6-diazaspiro [2.4]heptane-4,7-dione compound of formula (I) and the process of preparation thereof. The present invention also relates to the compound of formula (I) and its use in the preparation of sulfinpyrazone uricosuric drug or its derivatives/analogues. The compound of formula (I) is useful as anti-malarial, anti-microbial, anti-bacterial, anti-inflammatory, COX-2 inhibition, and anti-analgesics agents.

IPC Classes  ?

• C07D 231/54 - Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
• C07D 231/34 - Oxygen atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached in position 4
• C07D 231/36 - Oxygen atoms with hydrocarbon radicals, substituted by hetero atoms, attached in position 4

Abstract

The present disclosure relates generally to the field of artificial photosynthesis. More particularly, the present disclosure provides an artificial photosynthesis device and a process for fabrication thereof. Aspects of the present disclosure also provide a photocatalytic material and a process for production thereof. Further aspect of the present disclosure relates to a process for production of C1/C2 compounds from CO2 and H2O with the help of the artificial photosynthesis device with a solar to fuel efficiency of 14.7%.

IPC Classes  ?

• B01J 35/39 - Photocatalytic properties
• B01J 23/68 - Silver or gold with arsenic, antimony, bismuth, vanadium, niobium, tantalum, polonium, chromium, molybdenum, tungsten, manganese, technetium or rhenium
• B01J 35/30 - Catalysts, in general, characterised by their form or physical properties characterised by their physical properties
• B01J 35/77 - Compounds characterised by their crystallite size
• B01J 37/02 - Impregnation, coating or precipitation
• B01J 37/08 - Heat treatment

Abstract

122-metal oxide supported onto a support, wherein the M2 metal oxide is decorated or deposited onto the support, and a process of preparation thereof. The present disclosure also relates to a proton exchange membrane fuel cell comprising said electrocatalyst as coated onto an electrode.

IPC Classes  ?

• B01J 23/63 - Platinum group metals with rare earths or actinides
• B01J 23/64 - Platinum group metals with arsenic, antimony, bismuth, vanadium, niobium, tantalum, polonium, chromium, molybdenum, tungsten, manganese, technetium or rhenium
• B01J 23/648 - Vanadium, niobium or tantalum
• B01J 37/025 - Impregnation, coating or precipitation using a distinct intermediate layer, e.g. substrate-support-active layer
• H01M 4/92 - Metals of platinum group
• H01M 4/90 - Selection of catalytic material
• H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells

Abstract

The invention relates to a one pot and one step process for the synthesis of substituted furans wherein said process comprises of treating methylene based substrate of formula A with oxetan-3-one of formula B in presence of a solvent and mild catalyst.

IPC Classes  ?

• C07D 307/26 - Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
• C07D 305/10 - Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members

Abstract

The invention describes a kit for detection of a target polynucleotide using a CRISPR effector system that comprises CAS9 from Francisella novicida, a synthetic sgRNA and a detection scheme based on binding and subsequent enzymatic cleavage of the target polynucleotide. The invention also describes a method for detection of a target polynucleotide using the kit. The kit can be applied to both pathogenic and non-pathogenic polynucleotides and can be used to distinguish polynucleotides different by a single mismatch without the need for sequencing. The kit can also be used for detection of COVID-19. The kit is economical, easy to assemble and provides a robust and rapid readout that can be appropriately adapted for point of care applications.

IPC Classes  ?

• C12Q 1/686 - Polymerase chain reaction [PCR]
• C07K 14/195 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria
• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
• C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage

Abstract

The present invention provides stereogenic 3,3-disubstituted 3-aminooxindole compounds of formula (I). In addition, the present invention provides a process for preparing a stereogenic 3,3-disubstituted 3-aminooxindole compound of formula (I) using isatins and N-methoxy benzamides in presence of highly abundant iron catalyst. The stereogenic 3,3-disubstituted 3-aminooxindole compound of formula (I) is useful in the preparation of various bio-relevant C3-aminated oxindoles. The present invention provides stereogenic 3,3-disubstituted 3-aminooxindole compounds of formula (I). In addition, the present invention provides a process for preparing a stereogenic 3,3-disubstituted 3-aminooxindole compound of formula (I) using isatins and N-methoxy benzamides in presence of highly abundant iron catalyst. The stereogenic 3,3-disubstituted 3-aminooxindole compound of formula (I) is useful in the preparation of various bio-relevant C3-aminated oxindoles.

IPC Classes  ?

• C07D 209/40 - Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
• C07B 59/00 - Introduction of isotopes of elements into organic compounds
• C07D 405/14 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
• C07J 43/00 - Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta[a]hydrophenanthrene skeleton

Abstract

A filtration unit assembly (100) to separate solid and liquid mixtures is disclosed. A mixture of a solid and a liquid enters the top dish (110) through one or more inlets provided on the top dish. The received mixture for filtration then passes through a rotating drum (140) that is housed within a shell (150). The mixture of the solid and liquid enters the rotating drum and is exposed to a screw action by the rotary motion of the rotating drum (140). The resulting screw action separates the solid and the liquid as the liquid gets sucked towards the axis while the solids are pushed away from the axis of rotation of the rotating drum. The rotating drum (140) may be provided with perforations to aid in separation. A system for filtration that includes a filtration unit assembly (100) is also disclosed.

IPC Classes  ?

• B01D 33/067 - Construction of the filtering drums, e.g. mounting or sealing arrangements
• B01D 33/11 - Filters with filtering elements which move during the filtering operation with rotary cylindrical filtering surfaces, e.g. hollow drums arranged for outward flow filtration

Abstract

22422 purity compared to those derived through WM and SG methods.

IPC Classes  ?

• B01J 20/08 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising oxides or hydroxides of metals not provided for in group comprising aluminium oxide or hydroxideSolid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising oxides or hydroxides of metals not provided for in group comprising bauxite
• B01J 20/06 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising inorganic material comprising oxides or hydroxides of metals not provided for in group
• B01J 21/06 - Silicon, titanium, zirconium or hafniumOxides or hydroxides thereof
• B01J 23/755 - Nickel
• B01J 35/30 - Catalysts, in general, characterised by their form or physical properties characterised by their physical properties

Abstract

The present invention relates to a recombinant vector for genome editing in rice. The vector comprises of GluB1 promoter of rice along with Cas 12 a gene and a guide RNA. Editing the targeted gene within localized tissue effectively mitigates the pleiotropic effect observed in non- targeted tissues, thus reducing the potential for unintended consequences. Tissue-specific genome editing (TSGE) plays a pivotal role in alleviating the metabolic burden on plants by restricting modifications to specific areas. The designed CRISPR-ESGE binary construct was introduced into Agrobacterium, which was then used to infect rice callus derived from seeds. The regenerated transformed plants were confirmed to contain the Cas12a gene, and the endosperm-specific expression of Cas12a was validated through RT-PCR analysis. Genome editing (GE) utilizing Cas12a offers distinct advantages over Cas9, which is characterized by heightened target specificity and decreased propensity for off-target effect, thereby potentially enhancing the grain starch content.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof
• C12N 9/22 - Ribonucleases

Abstract

The present invention provides novel water-soluble compositions comprising sesquiterpene coumarin enriched fractions containing different ratios of sesquiterpene coumarin derived from Ferula species for the treatment of Parkinson's disease via inhibition of MAOenzyme (MAO-A and MAO-B). The invention also provides a method of preparation of ethyl-acetate extract and sesquiterpene coumarin enriched fractions from asafoetida (Hing) that is oleo-gum-resin of Ferula assafoetida using silica gel column chromatography wherein the mobile phase consists of differing compositions of hexane, toluene, chloroform,ethyl-acetate, and methanol. The invention provides the method to prepare the formulation using a multistep process comprising of preparing sesquiterpene coumarin enriched fraction followed by preparing water-soluble formulation. The final composition improves the water solubility, imparts long-term stability, exerts MAO inhibitory activity, and improves pharmaceutical compliance.

IPC Classes  ?

• A61K 31/37 - Coumarins, e.g. psoralen
• A61K 9/107 - Emulsions
• A61K 36/23 - Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
• A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
• A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids
• A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
• A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
• A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
• A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

Abstract

The present invention relates to an aptamer for detection of Aflatoxin M1 mycotoxin where the aptamers comprise nucleotide sequence in any one or more of SEQ ID. No. 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, a homologous sequence or a functional fragment thereof. The present invention also provides a process for preparing said aptamers for detection of Aflatoxin M1 mycotoxin. The present invention also provides a kit comprising said aptamers for detection of Aflatoxin M1 mycotoxin and an electrochemical device comprising aptamers for detection of Aflatoxin M1 mycotoxin in food products.

IPC Classes  ?

• C12N 15/115 - Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith
• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
• G01N 33/02 - Food

Abstract

1123112323 linear aliphatic carbonyl (LAC).

IPC Classes  ?

• C08J 11/10 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation
• C08J 11/16 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with inorganic material
• C07C 4/22 - Preparation of hydrocarbons from hydrocarbons containing a larger number of carbon atoms by depolymerisation to the original monomer, e.g. dicyclopentadiene to cyclopentadiene
• C07C 45/00 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atomsPreparation of chelates of such compounds
• C08L 23/06 - Polyethene
• B01J 23/72 - Copper

Abstract

The present invention relates to a tricyclic compound of formula (I) and its analogue useful for the treatment of breast and ovarian cancer. In particular, the present invention relates to novel tricyclic compound as PARP1/2 inhibitor, designed to block the activity of the enzyme Poly (ADP-ribose) polymerase (PARP1/2), which plays a crucial role in DNA damage repair, particularly in cancer cells. The synthesized inhibitor molecules having improved solubility, bioavailability and no haematological toxicity can be useful in potential cancer therapies, and defects in DNA repair pathways.

IPC Classes  ?

• C07D 209/44 - Iso-indolesHydrogenated iso-indoles
• A61K 31/4035 - Isoindoles, e.g. phthalimide
• A61P 35/00 - Antineoplastic agents

Abstract

The present invention relates to mesoporous amine-functionalized silica catalysts with worm-hole or channel-like morphology, prepared using 3-aminopropyl trimethoxysilane (3- APTMS) or 3-aminopropyltriethoxysilane (APTES). The catalysts exhibit average pore diameters of 1-100 nm and specific surface areas of 100-1,000 m2/g. The preparation process involves mixing Pluronic P123 with hydrochloric acid at 30-40°C, followed by addition of a mixture of 3-APTMS or 3-APTES with tetraethyl orthosilicate (TEOS), and subsequent hydrothermal treatment. The choice of precursor determines morphology: 3- APTMS yields worm-hole structures, while 3-APTES produces channel-like structures. These catalysts efficiently convert epoxides and carbon dioxide into cyclic organic carbonates with excellent yield. Additionally, the invention discloses a process for preparing styrene carbonate-coated zinc anodes and assembling full cells incorporating these anodes, significantly enhancing the durability of aqueous rechargeable zinc-metal batteries (ARZMBs).

IPC Classes  ?

• B01J 35/61 - Surface area
• B01J 31/02 - Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
• B01J 29/03 - Catalysts comprising molecular sieves not having base-exchange properties
• C08K 9/06 - Ingredients treated with organic substances with silicon-containing compounds
• C07F 7/18 - Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages

Abstract

The present invention relates to a controlled release composition comprising at least an active ingredient, at least one polymer and at least one functionalized protein. The present invention also discloses a method of preparation of controlled release composition. The composition effectively provides wound healing properties in a controlled release manner having longer duration of action with improved biocompatibility and mechanical stability.

IPC Classes  ?

• A61K 9/70 - Web, sheet or filament bases
• A61K 47/42 - ProteinsPolypeptidesDegradation products thereofDerivatives thereof, e.g. albumin, gelatin or zein
• A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61K 38/00 - Medicinal preparations containing peptides
• A61K 31/4164 - 1,3-Diazoles
• A61L 15/44 - Medicaments
• A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
• A61P 31/04 - Antibacterial agents

Abstract

The present invention relates to a composition comprising an ethyl acetate leaf extract of T. Sebifera and at least one component selected from a group comprising seed oil, essential oil, cyclotide or combinations thereof optionally along with an excipient/carrier. The present invention also relates to a process of preparation of the composition and a method for controlling pests employing said composition.

IPC Classes  ?

• A01N 65/18 - Euphorbiaceae [Spurge family], e.g. ricinus [castorbean]
• A01N 65/22 - Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
• A01N 65/44 - Poaceae or Gramineae [Grass family], e.g. bamboo, lemon grass or citronella grass
• A01N 65/28 - Myrtaceae [Myrtle family], e.g. teatree or clove
• A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof

Abstract

The present invention relates to a highly sensitive nested multiplex PCR-based primer panel for the detection of Lumpy Skin Disease Virus (LSDV) in a biological sample obtained from bovine species and livestock animals In particular, the present invention provides a nested multiplex detection primer panel and a kit comprising the same, for the detection of Lumpy Skin Disease Virus (LSDV) and its variants thereof. The present invention also provides a multiplex primer panel for the PCR whole genome amplification and genotyping of Lumpy Skin Disease Virus (LSDV) to obtain genomic data, which can be useful in tracking the evolution of the Lumpy Skin Disease virus and correlating with disease severity. Therefore, the present invention emphasizes its utility in veterinary diagnostics, epidemiological studies, and disease management strategies related to vaccine development for Lumpy Skin Disease Virus (LSDV) infections in livestock.

IPC Classes  ?

• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
• C12Q 1/686 - Polymerase chain reaction [PCR]
• C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
• C12Q 1/6888 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
• C12Q 15/11 -

Abstract

The present invention relates to photocatalysts of formula I for controlled radical polymerization including photoinduced electron transfer-reversible addition-fragmentation chain transfer PET-RAFT polymerization. The present invention also discloses a process of preparation of polymers including copolymers, block copolymers, homopolymers and/or related polymers/copolymers where two or more monomers are reacted in presence of said a squaraine dye based photocatalyst of formula I, chain transfer agent (CTA), and light source, and optionally in presence of a catalyst activator in both batch and flow modes. The process of the present invention significantly reduces the induction period in the photocatalyzed controlled radical polymerization and also affords shorter reaction time of photocatalyzed controlled radical polymerization.

IPC Classes  ?

• B01J 35/39 - Photocatalytic properties
• B01J 31/02 - Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
• C08F 4/00 - Polymerisation catalysts
• C08F 2/46 - Polymerisation initiated by wave energy or particle radiation
• C08F 293/00 - Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule

Abstract

The present invention relates to the in-situ generation of low molecular weight ionomers to enhance the triple-phase boundary in a 3D structured carbon-supported catalyst and the process for its preparation and application thereof.

IPC Classes  ?

• C08F 220/06 - Acrylic acidMethacrylic acidMetal salts or ammonium salts thereof
• C08J 3/24 - Crosslinking, e.g. vulcanising, of macromolecules
• C08J 5/20 - Manufacture of shaped structures of ion-exchange resins
• C08F 2/48 - Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light
• C08F 222/10 - Esters
• H01M 8/02 - Fuel cellsManufacture thereof Details
• H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells

Abstract

The present invention relates to a palladium-metal (Pd-M) alloy-based electrocatalyst system for the concurrent electrochemical oxidation of biomass-derived components and green hydrogen generation. More specifically, the invention enables the selective oxidation of disaccharides such as lactose, maltose, sucrose, and other C12 molecules into oxygenated organic compounds, with formate being the predominant product under optimized conditions. The electrocatalyst operates efficiently in alkaline media at low applied potentials and moderate current densities (10–40 mA/cm²), facilitating high conversion rates and selectivity. The process is compatible with both batch and continuous flow electrolyzer setups and demonstrates long-term operational stability, making it suitable for scalable and sustainable energy and biomass valorization applications.

IPC Classes  ?

• C22C 5/04 - Alloys based on a platinum group metal
• C22C 5/06 - Alloys based on silver
• B01J 23/44 - Palladium
• B01J 23/50 - Silver
• C25B 11/04 - ElectrodesManufacture thereof not otherwise provided for characterised by the material

Abstract

A novel class of phosphorus-containing Rucaparib analogues were synthesized and evaluated as poly(ADP-ribose) polymerase (PARP) inhibitors. Two distinct series were designed: one incorporating a spacer and the other without a spacer. Pharmacokinetic evaluation of representative compounds demonstrated favorable oral bioavailability and improved metabolic stability relative to Rucaparib. Oral administration of compound 9 (20 mg/kg, twice weekly) resulted in significant tumor growth inhibition (71%) compared to vehicle control and showed superior efficacy over Rucaparib (100 mg/kg, 52% inhibition). Importantly, compound 9 exhibited no mortality or significant body weight loss, while Rucaparib-treated animals displayed slight weight reduction and mortality in the final week of treatment. Collectively, these results highlight phosphorus-containing Rucaparib analogues as a promising new class of PARP inhibitors with favorable pharmacological properties and therapeutic potential for the treatment of BRCA-mutant and homologous recombination–deficient cancers, particularly breast and ovarian malignancies.

IPC Classes  ?

• C07D 487/06 - Peri-condensed systems
• A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
• A61P 31/14 - Antivirals for RNA viruses

Abstract

The present invention discloses silicon-incorporated HDAC-6 inhibitors of formula (I) and the process of preparation thereof. The invention further relates to methods of treating a group consisting of idiopathic pulmonary fibrosis, hepatic fibrosis, and other fibrotic disorders such as cardiac, kidney, and skin fibrosis.

IPC Classes  ?

• C07D 209/04 - IndolesHydrogenated indoles
• C07D 209/56 - Ring systems containing three or more rings
• C07D 519/00 - Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or
• C07D 521/00 - Heterocyclic compounds containing unspecified hetero rings
• C07F 7/08 - Compounds having one or more C—Si linkages
• A61P 11/00 - Drugs for disorders of the respiratory system

Abstract

The present invention generally relates to biomedical engineering and regenerative medicine. Specifically, the present invention relates to development of advanced tracheal splints for the treatment of tracheal disorders. More particularly, the present invention relates to a process for preparation of biodegradable hybrid polymer splints, the process comprising, a) carrying polymerization reaction of polycaprolactone (PCL) with pectin in presence of a catalyst to obtain pectin-g-PCL; and b) 3D printing of pectin-g-PCL. The present invention also relates to a biodegradable hybrid polymer splint comprising honeycomb structure, rectangular convolutions or combination thereof. Further, the tracheal splints are designed to support tracheal regeneration, enhance cellular interaction, and eliminate the need for additional surgical procedures for removal.

IPC Classes  ?

• C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones
• C08G 63/08 - Lactones or lactides
• C08L 101/16 - Compositions of unspecified macromolecular compounds the macromolecular compounds being biodegradable
• C08L 5/06 - PectinDerivatives thereof

Abstract

The present invention generally relates to the metal batteries. The present invention discloses sodium-plated host material comprising sodium-plated or bonded with metal modified electrospun carbon nanofiber, wherein the metal is selected from tin (Sn), silicon (Si), germanium (Ge), zinc (Zn), cobalt (Co) and lead (Pb). The present invention also discloses a process for preparation of sodium-plated host material and a full cell comprising the sodium- plated host material.

IPC Classes  ?

• C25B 11/04 - ElectrodesManufacture thereof not otherwise provided for characterised by the material
• H01M 4/40 - Alloys based on alkali metals
• H01M 4/42 - Alloys based on zinc
• H01M 4/38 - Selection of substances as active materials, active masses, active liquids of elements or alloys
• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 10/052 - Li-accumulators

Abstract

This invention provides a novel potent α/β and β/α hybrid peptides, containing tBu-β3,3-Acec and β2,2- Acec, which inhibit the cancer cell lines including HCT-116, MCF-7, MIA-PACA and A549. Among all the hybrid peptides, P-12 was the most potent against colon cancer with an IC50 value of 3.3 pM±0.27. Furthermore, P-12 effectively triggered the potential of mitochondrial membrane and decrease the formation of Reactive oxygen species (ROS). The percentage inhibition of tumor growth in HCT-116 was 51% in the 5FU treated group, whereas it was around 77% in the P-12 treated groups. Moreover, no significant loss in body weight and substantial difference in serum biochemical parameters was observed in the P-12 treated group compared to the control except for glucose and triglycerides.

IPC Classes  ?

• A61K 38/10 - Peptides having 12 to 20 amino acids
• A61K 38/00 - Medicinal preparations containing peptides
• C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
• A61P 35/00 - Antineoplastic agents

Abstract

The present invention discloses a binder for electrochemical device comprising a non-conjugated polymer linked with a redox active moiety, wherein the non-conjugated polymer is selected from poly(2-ethyl-2-oxazoline), vinyl polymer, polyurethane polymer, zwitterionic polymer, polythiourea polymer and a combination thereof and the redox active moiety is selected from ferrocene, anthraquinone and a combination thereof, wherein the non-conjugated polymer is linked with redox active moiety by carbonyl linkage, carbamate linkage, amide linkage, N-substitution or hexamethylene group and comprises of amide functionality, and optionally a host compound selected from cyclodextrin, azido cyclodextrin, calix(n)arene derivative, cucurbit(7)uril derivative, polyethylene glycol polymer and a combination thereof. The present invention further discloses a process for preparation thereof of the binder, an electrode comprising the binder and an electrochemical cell or a battery comprising the binder of the present invention. The present invention discloses the non-conjugated polymer linked with redox active moiety which can act as binder and electrocatalyst in the batteries. The battery with the binder of present invention showed the best-known performance of a stable specific capacity beyond 1000 charge-discharge cycles.

IPC Classes  ?

• C08G 59/17 - Polycondensates modified by chemical after-treatment by monocarboxylic acids or by anhydrides, halides or low-molecular-weight esters thereof by acrylic or methacrylic acid
• C08G 71/04 - Polyurethanes
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 4/139 - Processes of manufacture
• H01M 4/60 - Selection of substances as active materials, active masses, active liquids of organic compounds

Abstract

The present invention relates to the method for efficient removal of phenolic compounds from wastewater generated from petroleum industry. The method is two-step process. The first step is a pre-treatment process which operates through adsorption-based separation using granular activated carbon. The wastewater in this step is allowed to pass through a column packed with granular activated carbon. In the second step, the pretreated wastewater is subjected to membrane-based treatment. The present invention also relates to the design of a special membrane for effective removal of phenolic compounds from waste water. The membrane formulation includes polysulfone as the main polymeric matrix and carbon dots coated powdered activated carbon as the additive which acts as the active agent for the removal of phenolic compounds. The membranes are designed in two different types, viz., (i) flat sheet and (ii) hollow fiber. The membrane-based separation using the flat sheet membranes can be done with the help of a dead-end filtration set up. In case of hollow fiber membranes, a cylindrical membrane module with a large number of hollow fiber membranes is designed. The membranes are reusable with excellent separation efficiency. The membrane module has proper feed inlet, outlet for permeates and outlet for retentates. This present invention provides removal of ~99% phenolic compounds from petroleum industry wastewater.

IPC Classes  ?

• C08L 81/06 - PolysulfonesPolyethersulfones
• B01D 71/68 - PolysulfonesPolyethersulfones
• B01D 71/02 - Inorganic material
• B01D 71/06 - Organic material

Abstract

The present invention relates to biodegradable cross-linked alkyl polysaccharide dispersion materials for coating on lignocellulose sheets as a promising alternative to traditional plastic mulch in sustainable agricultural practices and process for preparation thereof. More particularly, the present invention relates to biodegradable cross-linked alkyl polysaccharide dispersion coating material coated on lignocellulose sheets having tensile strength 15‒20 MPa, tensile index of 25‒30 N.m/g wherein the coating dispersion material is obtained from the Michael addition reaction of polysaccharide (chitosan), acrylic crosslinker and further alkylation in presence of alkylamine in 93%‒95%yield. The aim of the invention is to mitigate environmental pollution and reduce dependence on non-renewable resources. The present invention provides a method of coating to prepare water repellent lignocellulose sheet/paper with a stability of 50‒70 days in outdoor environmental conditions and biodegradation in soil within 30‒45 days.

IPC Classes  ?

• C09D 105/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof
• C09D 105/00 - Coating compositions based on polysaccharides or on their derivatives, not provided for in groups or
• C08K 5/17 - AminesQuaternary ammonium compounds
• C08K 5/00 - Use of organic ingredients
• C08J 7/04 - Coating

Abstract

The present invention relates to a pesticidal composition comprising an effective amount of phytochemical(s), which optionally combined with commercially known pesticide and agrochemically acceptable excipients or vehicle, and a process for the preparation thereof. The present invention provides a pesticidal composition, which results in enhanced insecticidal efficacy, lower effective doses, multi-target pest control and decreases the possibility of developing the resistance in insects.

IPC Classes  ?

• A01N 43/16 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom six-membered rings with oxygen as the ring hetero atom
• A01N 43/40 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
• A01N 43/90 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
• A01N 65/00 - Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
• A01N 25/14 - Powders or granules wettable

Abstract

The invention pertains to a Plug-in modular functional device embedded with an electrode assembly for the treatment of pharmaceutical/industrial wastewaters. The invention provides electrochemical treatment along with biological treatment to address the challenges posed by complex industrial/chemical wastewater. The developed device presents an efficient and scalable solution for the treatment of complex organic and inorganic pollutants through bio- electrocatalytic process. It is able to achieve color removal (89.75%), COD removal (90.4%), TOC removal (90.4%), TN removal (53.74%), Amine removal (67.67%), Azo reductase activity (37.9 U). The invented device can be embedded/integrated to biological unit operation of the existing effluent treatment plants (without modification) or with a new ETP design to intensify the removal of organics and inorganics from chemical wastewater. The device improves performance of treatment in terms of carbon (COD/TOC) removal, Nutrients removal, colour removal and TDS removal by 15-35% augmented efficiency based on the nature of wastewater being treated.

IPC Classes  ?

• C02F 3/34 - Biological treatment of water, waste water, or sewage characterised by the microorganisms used
• C02F 9/00 - Multistage treatment of water, waste water or sewage
• C02F 101/30 - Organic compounds
• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• C02F 1/52 - Treatment of water, waste water, or sewage by flocculation or precipitation of suspended impurities

Abstract

The present invention relates to a non-invasive magneto-acoustic apparatus for healthy tissue healing and cancer regression comprising at least one pulsed ultrasound unit (LIPUS), at least one permanent magnet, at least one module housing, at least one permanent magnets, at least one control system for controlling pulsed ultrasound unit to energize the unit with desired pulse duration, intensity and active/ON time. The invention is to synchronously use the low intensity pulsed ultrasound (LIPUS) and static magnetic field (SMF) to selectively activate cellular activities specific to cartilage, bone, skin leading to accelerated tissue healing, regeneration. The invention apparatus is to inhibit cancer cellular activities specific to cancers of breast, skin, bone leading to enhanced cancer regression, while leaving the healthy cells unaffected using magneto-acoustic apparatus appropriately. The apparatus exhibit no toxicity to healthy cells and can reduce overall treatment time and costs due to accelerated tissue repair and tumor regression.

IPC Classes  ?

• A61N 7/00 - Ultrasound therapy
• A61N 2/00 - Magnetotherapy

Abstract

The present invention relates to metal coated electromagnetic interference (EMI) shields and specifically the present invention relates to a mesh or cloth coated with metal plating solution for use in shielding from EMI and wireless communication signals, and a method of producing the same.

IPC Classes  ?

• C23C 18/00 - Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coatingContact plating
• B32B 15/00 - Layered products essentially comprising metal

Abstract

Methods and formulations for managing the hydrate deposition and growth in oil and gas pipelines have been disclosed. Herein, the effective hydrate-inhibiting/anti-agglomerating formulations comprising combinations of polysaccharides/gelling agents along with the specific solvation packages in precise ratios contribute to managing the hydrophobic, hydrophilic, or amphiphilic nature of the formulations as per the requirement of production fluids/hydrate former compositions. These formulations are easily biodegradable, non-corrosive, and environmentally friendly.

IPC Classes  ?

• C09K 8/52 - Compositions for preventing, limiting or eliminating depositions, e.g. for cleaning
• C09K 8/68 - Compositions based on water or polar solvents containing organic compounds
• C09K 8/88 - Compositions based on water or polar solvents containing organic compounds macromolecular compounds
• C09K 8/524 - Compositions for preventing, limiting or eliminating depositions, e.g. for cleaning organic depositions, e.g. paraffins or asphaltenes

Abstract

Provided herein are chimeric α-amylase inhibitors with enhanced inhibition potential, genes and genetic constructs encoding the inhibitors, and vectors encompassing the genetic sequences. Also provided herein are methods of using the inhibitors and recombinant proteins namely, chimeric Amaranthaceae α-amylase inhibitor proteins, genetic sequences, genetic constructs, and vectors in the field of insect and pest control.

IPC Classes  ?

• C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants
• A01N 63/50 - Isolated enzymesIsolated proteins
• A01P 7/04 - Insecticides
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression

Abstract

The present invention generally relates to cathode material (108) for aqueous rechargeable zinc ion battery. Specifically, the present invention relates to modified cathode material (108) comprising perylene-based polyimides. More particularly, the present invention relates to synthesis of organic electrode materials including PI-COF and PI-DAAQ based on carbonyl groups. Further, the present invention relates to synthesis of PI-COF and PI-DAAQ by incorporating a redox-active perelyetertacarboxylic dianhydride (PTCDA) as the connecting unit.

IPC Classes  ?

• C25B 11/04 - ElectrodesManufacture thereof not otherwise provided for characterised by the material
• C08G 73/10 - PolyimidesPolyester-imidesPolyamide-imidesPolyamide acids or similar polyimide precursors
• H01M 4/02 - Electrodes composed of, or comprising, active material
• H01M 4/137 - Electrodes based on electro-active polymers
• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/583 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx
• H01M 4/60 - Selection of substances as active materials, active masses, active liquids of organic compounds
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 4/66 - Selection of materials

Abstract

The present invention generally relates to electrochemical energy storage and battery technology. Specifically, the present invention relates to bifunctional electrocatalyst for metal-air electrochemical device. More particularly, the present invention relates to Nickel-Iron metal¬ organic framework (NF-MOF) as bifunctional electrocatalyst for zinc-air battery application. Further, the present invention relates to synthesis of Nickel-Iron metal-organic framework (NF- MOF) by refluxing method.

IPC Classes  ?

• B01J 27/24 - Nitrogen compounds
• H01M 4/90 - Selection of catalytic material
• H01M 4/88 - Processes of manufacture
• H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
• C25B 11/091 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds

Abstract

The present invention provides a composition for material comprising brine sludge waste and a process for the preparation thereof process for preparation of flexible, functional, and moldable material using advanced Chem-heat treated brine sludge-based composition via solvent-free route for developing samples of various dimensions. The present invention involves developing desired, suitable, and appropriate phases possessing uniform and homogenous matrix in the developed material. Thus, designing molecular moieties in the developed process leads to forming tightly bound three-dimensional structures, strengthening the developed advanced chemically designed material which is cost-effective, non-toxic, highly versatile (can be bent or shaped to fit around curves and corners), durable, easy to install, safe with superior performance and economically feasible advanced flexible, functional and moldable material with a homogeneous uniform matrix using advanced dual chem-heat treated brine sludge based composition for a broad application spectrum.

IPC Classes  ?

• G21F 1/10 - Organic substancesDispersions in organic carriers
• C02F 11/00 - Treatment of sludgeDevices therefor
• C02F 11/13 - Treatment of sludgeDevices therefor by de-watering, drying or thickening by heating

Abstract

The present study reveals a process to develop glass foam/ bricks (of compressive strength >3MPa) and tiles (of Thermal conductivity ≤0.1 W/m.K) utilizing 98-99 % waste glasses obtained from various sources and by use of single foaming agent helps to generate identical pore within the foam body and thereby to maintain uniform porosity. Low sintering temperature maintains high viscosity which keeps small pore diameter and less amount of foaming agent prevents collapsing of bubble during foaming and enhancing closed porosity.

IPC Classes  ?

• C03B 19/08 - Other methods of shaping glass by foaming
• C03B 19/06 - Other methods of shaping glass by sintering
• C03C 11/00 - Multi-cellular glass
• C03C 1/00 - Ingredients generally applicable to manufacture of glasses, glazes or vitreous enamels
• C04B 14/24 - Glass porous, e.g. foamed glass

Abstract

The present invention relates to a hybrid pyrano[2,3-c]pyrazole-pyrazolones and analogous compounds of Formula 3; and a process for the preparation thereof. The invention further relates to identification of bioactivities of synthesized novel hybrid pyrano[2,3-c]pyrazole- pyrazolones. The novel hybrid pyrano[2,3-c]pyrazole-pyrazolones of Formula 3 displayed useful neuroprotective property and inhibited acetylcholine esterase enzyme at the lowest concentration. These compounds were also found to cross the Blood-Brain Barrier.

IPC Classes  ?

• C07D 491/052 - Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
• A61K 31/415 - 1,2-Diazoles
• A61K 31/4162 - 1,2-Diazoles condensed with heterocyclic ring systems
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• A61P 35/00 - Antineoplastic agents

Abstract

Present invention discloses a novel green fluorescence silver nanodots prepared with naringenin, a flavanone, by a near green synthesis without adding harsh reducing agent such as sodium borohydride and others. Particularly, the present invention provides silver nanodots (quantum dot like nanostructure) of average size 3.5 nm. The preparation method is a unique kind of single pot green synthesis method wherein no common and strong reagent like sodium borohydride, ascorbic acid surfactant, thiol containing reagent or protein solutions are used. Alternatively, a simple flavanone, aromatic organic molecule that contains three OH groups is used both as a mild reducing and stabilizing agent for the preparation of the particles at room temperature (25°C). The aqueous suspension of the invented nanodots product is quite stable in room temperature. It produces strong green fluorescence with average fluorescence lifetime ~2.37 ns and produces a large stocks shift.

IPC Classes  ?

• C09K 11/58 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing copper, silver or gold
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
• B82Y 15/00 - Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
• B82Y 20/00 - Nanooptics, e.g. quantum optics or photonic crystals

Abstract

After ban on single-use plastics, there is a great demand on biodegradable, green and sustainable bio-resin coating to replace the plastics liners for hydrophobic and moisture resistant paper-based packaging. The present invention intends to disclose the process for synthesis of bio-resin starting from epoxides of castor oil and development of coating on cellulosic paper substrate through condensation. The coating is suitable for fatty food and beverages filling and storage. The present invention also disclosed the biodegradability of the coated papers as well as the removal of the coating for reusability of the papers after consumption. The adopted process involves use of green starting material, industrially viable and cost-effective.

IPC Classes  ?

• C09D 191/00 - Coating compositions based on oils, fats or waxesCoating compositions based on derivatives thereof
• D21H 19/10 - Coatings without pigments
• D21H 21/16 - Sizing or water-repelling agents

Abstract

The present invention relates to an electrocatalyst comprising monometallic or bimetallic nanoparticles decorated onto a composite containing aluminium oxyhydroxide supported nitrogen doped reduced graphene oxide (AlOOH/NGr or ANGr), and its process of preparation thereof. The present invention also relates to a half or full direct ammonia fuel cell (DAFC) comprising said electrocatalyst. The electrocatalyst of the present invention provides improves the electronic conductivity of the overall system and contributes towards the better AOR activity.

IPC Classes  ?

• C25B 11/091 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds
• H01M 4/90 - Selection of catalytic material
• H01M 8/22 - Fuel cells in which the fuel is based on materials comprising carbon or oxygen or hydrogen and other elementsFuel cells in which the fuel is based on materials comprising only elements other than carbon, oxygen or hydrogen
• H01M 4/92 - Metals of platinum group
• B01J 23/46 - Ruthenium, rhodium, osmium or iridium
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites

Abstract

The present invention relates to novel transparent free-standing Al (III) incorporated Li-ion based solid-gel electrolyte for enhancement of optical contrast of electrochromic device. More particularly, the present invention relates to Al (III) incorporated Li-ion based free-standing solid-gel electrolyte for enhancement of optical contrast which comprises of a unique transparent, flexible, free-standing, solid-gel polymer electrolyte, its composition and process for preparation thereof. The unique Al(iii) incorporated Li-ion based free-standing solid-gel electrolyte reveals a high optical contrast, as well as faster switching kinetics from bleached state to colored state or vice versa on changing the external voltage. A significant increase in optical contrast from 50% to 82% is obtained with a faster switching kinetics.

IPC Classes  ?

• H01M 10/0565 - Polymeric materials, e.g. gel-type or solid-type
• H01M 10/056 - Accumulators with non-aqueous electrolyte characterised by the materials used as electrolytes, e.g. mixed inorganic/organic electrolytes
• H01M 10/058 - Construction or manufacture
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• G02F 1/1514 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour based on an electrochromic effect characterised by the electrochromic material, e.g. by the electrodeposited material
• G02F 1/153 - Constructional details
• G02F 1/152 -

Abstract

The present work discloses polymeric bead formulation and process for preparation the same. The polymeric bead formulation comprise fennel oil as a extended release system for insecticidal activity against Aedes agypti, Anopheles stephensi, and wild mosquito larvae. This study was carried out by emulsifying fennel oil in an aqueous sodium alginate solution blended with HPMC and the fabrication of beads was then followed by an ionotropic gelation method using CaCl2 as a cross-linker. The in-vivo larvicidal bioassay showed that the fennel oil-loaded polymeric beads resulted in 100% mortality of Aedes agypti, Anopheles stephensi, and wild mosquito larvae within 24 hours. These results confirm that the fennel oil-loaded polymeric beads exhibited good entrapment efficiency, extended release property, and excellent insecticidal activity.

IPC Classes  ?

• A01N 65/10 - Apiaceae or Umbelliferae [Carrot family], e.g. parsley, caraway, dill, lovage, fennel or snakebed
• A01N 25/10 - Macromolecular compounds
• A01N 25/12 - Powders or granules
• A01N 25/30 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
• A01P 7/04 - Insecticides

Abstract

The present invention provides an automated method (100) and system (200) for identifying hydrogen storage properties of metal alloys. More particularly, the invention provides a method and system for identification of materials for solid hydrogen storage in multi-component metal alloys. The system (200) can predict hydrogen weight capacity and equilibrium plateau pressure at different temperatures along with enthalpy of hydride formation of multi-component metal alloys with high predictability and case of interpretation. Further, a suitable alloy can be identified by the method (100) employed using the system (200) for hydrogen storage applications based on the hydrogen weight capacity and the equilibrium plateau pressure at different temperatures and enthalpy of hydrogenation, wherein an absorption temperature of the suitable alloy plays a vital role.

IPC Classes  ?

• G16C 60/00 - Computational materials science, i.e. ICT specially adapted for investigating the physical or chemical properties of materials or phenomena associated with their design, synthesis, processing, characterisation or utilisation
• G16C 20/70 - Machine learning, data mining or chemometrics

Abstract

The present disclosure relates to a novel process for the depolymerization of waste polycarbonates (PC), into valuable carbamates and diols through a greener approach. Specifically, present invention relates to an efficient and environmentally friendly process to depolymerize polycarbonates into monoaminocarbamate, bisaminocarbamate, and their diol without employing catalysts or additives and operates at ambient temperature under air, utilizing green solvents.

IPC Classes  ?

• C08J 11/10 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation
• C08J 11/18 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material

Abstract

The present invention relates to composite scaffold for cartilage regeneration and its process thereof. The composition of composite scaffold is comprised of 7.5-15wt% PGS, 7.5-15wt% PCL, 6-8wt% of protein/growth factor loaded SGNP, and 50-100µg of protein (BSA)/growth factor (GDF-5) offering excellent protein encapsulation efficiency into fibrous matrix, excellent protection of structural and functional properties of encapsulated proteins against process related stresses and capable of delivering proteins in a sustained therapeutic dosing manner for a prolonged period of time.

IPC Classes  ?

• A61L 27/54 - Biologically active materials, e.g. therapeutic substances
• A61L 27/22 - Polypeptides or derivatives thereof
• A61L 27/22 18 -

Abstract

The present invention relates to the process of enrichment of Phytocannabinoids namely CBD and Δ9-THC from the dried aerial part (leaves and inflorescence) of Cannabis sativa. The present invention also relates to the preparation of formulation having enriched CBD and THC by combining with appropriate acceptable excipients such as nutriose, dextrin and maltodextrin. The present invention also discloses the use of the phytocannabanoids enriched blend for the management of pain including cancer pain & general pain.

IPC Classes  ?

• A61K 31/00 - Medicinal preparations containing organic active ingredients
• A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
• C07C 37/72 - SeparationPurificationStabilisationUse of additives by physical treatment by liquid-liquid treatment
• C07D 311/80 - DibenzopyransHydrogenated dibenzopyrans

Abstract

The present invention is directed to the cells, compositions, and methods for the production of and purification of recombinant protein. In particular, the invention is directed to have enhanced soluble expression of interleukin 1-receptor antagonist by means of an optimized novel polynucleotide sequence and host transformed with the said polynucleotide. The invention also provides a method for increased production and purification of interleukin 1-receptor antagonist (IL-1Ra) wherein, the polynucleotide of the present invention is used to transform a suitable host resulting in over-expression of corresponding proteins and a method for isolating the expressed polypeptide. The invention also relates to the purification method for of interleukin 1-receptor antagonist (IL-1Ra) using multimodal chromatography as well as characterization of properly folded of interleukin 1-receptor antagonist (IL-1Ra) protein.

IPC Classes  ?

• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C07K 14/54 - Interleukins [IL]
• C12N 15/25 - Interleukin-1
• C07K 1/16 - ExtractionSeparationPurification by chromatography

Abstract

The present disclosure relates to FeSe2 decorated porous nitrogen and sulfur-doped carbon spheres (FSPNSCS) composite material as cathode for the aluminium ionic battery (AIB) or aluminium aqueous battery. The present invention also relates to a process of preparation of said composite material comprising FeSe2 with nitrogen and sulphur co-doped porous carbon spheres. The invention also relates to aluminium aqueous batteries containing FeSe2 material as cathode.

IPC Classes  ?

• C01G 49/00 - Compounds of iron
• H01M 10/056 - Accumulators with non-aqueous electrolyte characterised by the materials used as electrolytes, e.g. mixed inorganic/organic electrolytes
• H01M 4/13 - Electrodes for accumulators with non-aqueous electrolyte, e.g. for lithium-accumulatorsProcesses of manufacture thereof
• H01M 4/58 - Selection of substances as active materials, active masses, active liquids of inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFySelection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates
• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• H01M 10/058 - Construction or manufacture

Abstract

Rice bran lyso-gums is a new class of by-product obtained during degumming of crude rice bran oil using bio-catalyst. Presently, this particular by-product is having very limited applications and is fetching negligible value to the industry. On the other hand, it contains lyso -phospholipids which has known applications in food, surfactant, pharmaceutical and cosmetics industries. The present invention relates to processes for possible value addition to crude rice bran lyso-gums- an unexplored by-product of rice bran oil refinery. It describes efficient processes for possible upgradation, modification, enrichment and purification of crude rice bran lyso-gums to obtain lyso-PC enriched rice bran lyso-lecithin having lighter colour by using various unit operation like drying, bleaching, solvent fractionation and chromatographic separation techniques in sequential manner.

IPC Classes  ?

• C11B 3/00 - Refining fats or fatty oils
• C11B 1/10 - Production of fats or fatty oils from raw materials by extracting
• C11B 3/12 - Refining fats or fatty oils by distillation
• C07F 9/10 - Phosphatides, e.g. lecithin

Abstract

The present invention discloses a continuous process for the direct capture of CO2 from the atmospheric air. The present invention specifically discloses the use of phase change amine (solid-liquid) absorbents with suitable solvents, yielding efficient CO2 capture from air. This cyclic approach establishes a continuous method for capturing CO2 directly from air, characterized by significantly reduced energy demand. More particularly, the present invention provides an energy efficient method for capturing CO2 directly from air, using phase change amines, with low regeneration energy.

IPC Classes  ?

• B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
• B01D 53/62 - Carbon oxides
• B01D 53/74 - General processes for purification of waste gasesApparatus or devices specially adapted therefor
• B01D 53/77 - Liquid phase processes
• B01D 53/92 - Chemical or biological purification of waste gases of engine exhaust gases
• B01D 53/96 - Regeneration, reactivation or recycling of reactants

Abstract

The present invention relates to a system and a process for enhanced hydrogen (H₂) and short- chain fatty acid (SCFA) production using both untreated as well as thermally pretreated food waste (TCP-FW) in continuous mode. The process employs non-sacrificial, conductive, and biocompatible electrodes and optimizes the carbon-to-nitrogen (C/N) ratio of TCP-FW for improved H₂ yields. The invention minimizes CO₂ formation while maximizing H₂ and SCFA production. The process is scalable, demonstrated in a 60-L continuous reactor with an L/D ratio of 10, achieving a production rate of 260 L H₂/day per kg COD with productivity of 10.84 L/h. This method offers a sustainable approach to low-carbon hydrogen production by utilizing municipal biogenic solid waste, reducing greenhouse gas emissions, and generating SCFA as a valuable by-product.

IPC Classes  ?

• B09B 3/60 - Biochemical treatment, e.g. by using enzymes
• B09B 3/00 - Destroying solid waste or transforming solid waste into something useful or harmless
• C12P 7/6409 - Fatty acids
• C12P 3/00 - Preparation of elements or inorganic compounds except carbon dioxide

Abstract

The present invention relates to a cell-penetrating peptide and its derivatives to inhibit α-synuclein fibrillation. The present invention specifically relates to a peptide-based inhibitor of Parkinson's Disease. The present invention discloses the identification of the peptides permeable to blood brain barrier for inhibition. α-synuclein fibril formation is observed in the presence of peptides as indicated by SEQ. ID-7, SEQ. ID-8 wherein the SEQ. ID-7, SEQ. ID-8 are truncated versions of SEQ. ID-4 having the homology of 83% and 75% respectively. It provides a peptide having an amino acid sequence of Formula 1. The present invention also provides a pharmaceutical composition comprising a peptide of Formula 1 along with the pharmaceutically acceptable excipient(s) having inhibitory activity against β-sheet polymerisation of amyloidogenic proteins. The analysis showed that peptides corresponding to SEQ. ID-7, SEQ. ID-8 are better inhibitors than SEQ. ID-4 against α-synuclein fibrillation.

IPC Classes  ?

• C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
• A61K 38/00 - Medicinal preparations containing peptides
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids

Abstract

222 2 2 directly from air, using phase change amines, with low regeneration energy.

IPC Classes  ?

• B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
• B01D 53/62 - Carbon oxides
• B01D 53/92 - Chemical or biological purification of waste gases of engine exhaust gases
• B01D 53/74 - General processes for purification of waste gasesApparatus or devices specially adapted therefor
• B01D 53/96 - Regeneration, reactivation or recycling of reactants
• B01D 53/77 - Liquid phase processes

Abstract

The present invention generally relates to a reverse atom transfer radical depolymerization method to depolymerize polyolefins into its corresponding alkyl monomers and short-chain alkyl halides with moderate depolymerization yield. Also, the present invention relates to repolymerizing of the depolymerized monomers to polyolefins. The depolymerization process only requires 1-2 steps and works under mild conditions. Moreover, the monomer, produced does not require any additional separation.

IPC Classes  ?

• C08J 11/16 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with inorganic material
• C08F 2/00 - Processes of polymerisation
• C08F 2/48 - Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light
• C08F 8/20 - Halogenation

Abstract

The present disclosure relates to a template free modified ferrierite zeolite has a Si/Al ratio in the range of 12 to 13. Further, the present disclosure also provides a method of preparation of a modified ferrierite zeolite. The present disclosure also provides a process of conversion of oleic acid to iso-stearic acid by using the modified ferrierite zeolite. The commercial grade oleic acid conversion is about 85% and isostearic acid selectivity is about 86%.

IPC Classes  ?

• C01B 39/44 - Ferrierite type, e.g. types ZSM-21, ZSM-35 or ZSM-38
• B01J 29/00 - Catalysts comprising molecular sieves
• B01D 53/86 - Catalytic processes
• B01J 29/65 - Crystalline aluminosilicate zeolitesIsomorphous compounds thereof of the ferrierite type, e.g. types ZSM-21, ZSM-35 or ZSM-38
• C07C 4/06 - Catalytic processes
• C07C 5/27 - Rearrangement of carbon atoms in the hydrocarbon skeleton

Abstract

The present invention relates to a Microbial-bio-electrochemical reactor (M-BEC) for enhanced bio-H2 production. More particularly, the present invention relates to a reactor for the removal of biodegradable contaminants from wastewater using biological processes. The developed system is intrinsically coupled the dark fermentation with microbial-electrochemical process together into a next generation bio-reactor which employs biocatalyst to convert chemical energy stored in organics to hydrogen energy. The coupled M-BEC technology has developed to aimed towards the enhancement of the metabolic activity of electrochemically active biocatalyst by supplying organic/inorganic nutrients, electron acceptors, or donors, which felicitate the electro-hydrogenesis in a membrane less single cell reactor for bio- Hydrogen (green H2) production. The present invention also relates to a process for treatment of contaminated water which contains a large amount of biodegradable suspended solids and high concentrations of BOD and COD and enables bio-hydrogen generation with simultaneous removal of biodegradable TSS from wastewater.

IPC Classes  ?

• H01M 8/16 - Biochemical fuel cells, i.e. cells in which microorganisms function as catalysts

Abstract

METHYLENE ENYL ESTER KETO COMPOUNDS AND A METAL-FREE CATALYTIC PROCESS OF PREPARATION THEREOF The present invention generally relates to a field of catalysis and ligand design in organocatalytic and organometallic chemistry. Specifically, the present invention relates to use of N-Heterocyclic carbenes (NHCs) as catalysts for the metal-free Tsuji-Trost type allylation reaction of aldehydes with Morita-Baylis-Hillman adducts. More particularly, the present invention relates to compound of formula 1 representing the substituted methylene enyl ester keto compounds of formula I and substituted methylene dienyl ketone diester compounds of formula II, and process of preparation thereof. Further, the present invention relates to preparation of Sacubitril API using said compound of formula I as starting material or intermediate.

IPC Classes  ?

• C07C 69/738 - Esters of keto-carboxylic acids
• C07D 333/24 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
• C07C 69/618 - Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
• C07D 213/55 - AcidsEsters
• B01J 31/02 - Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides

Abstract

The present invention relates to fabricating a pilot-scale solar tracker continuous flow reactor for the photochemical reaction. The present invention, particularly, relates to a pilot scale process for synthesis of formula 1, which key intermediates of various intermediate of various angiotensin II receptor blockers (ARBs). More particularly, the present invention relates to an integrated continuous flow reactor platform with Bayesian optimization (BO) assisted reaction optimization that can autonomously explore the optimal conditions for photochemical bromination reaction for the synthesis of Formula 1 and Formula 2. Moreover, autonomously explored bromination conditions are seamlessly integrated with continuous flow tools to synthesize, extract, and purify the Angiotensin II receptor blocker intermediate (formula 3).

IPC Classes  ?

• C07D 233/02 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
• C07D 235/04 - BenzimidazolesHydrogenated benzimidazoles
• C07D 235/18 - BenzimidazolesHydrogenated benzimidazoles with aryl radicals directly attached in position 2
• B01J 19/12 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing electromagnetic waves

Abstract

The present invention generally relates to a field of material science and chemistry. Specifically, the present invention relates to synthesis and characterization of lead-free hybrid organic-inorganic Perovskite compounds for metal ion sensing applications. More particularly, the present invention relates to lead-free low dimensional manganese (Mn)- and copper (Cu)- based hybrid organic-inorganic perovskites (HOIPs) for visual fluorometric Pb2+ ion detection. Further, the present invention relates to synthesis of lead-free low dimensional manganese (Mn)- and copper (Cu)-based hybrid organic-inorganic perovskites (HOIPs) via mechanochemical synthesis methodology.

IPC Classes  ?

• C07F 1/08 - Copper compounds
• C01G 53/70 - Complex oxides containing nickel and at least one other metal element containing rare earths, e.g. LaNiO3
• C01G 51/68 - Complex oxides containing cobalt and at least one other metal element containing alkaline earth metals, e.g. SrCoO3 containing rare earths, e.g. (La0.3Sr0.7)CoO3
• C07C 209/00 - Preparation of compounds containing amino groups bound to a carbon skeleton
• C07C 211/04 - Mono-, di- or tri-methylamine
• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials

Abstract

1422.

IPC Classes  ?

• B01J 35/39 - Photocatalytic properties
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
• B01J 21/06 - Silicon, titanium, zirconium or hafniumOxides or hydroxides thereof
• B01J 23/16 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of arsenic, antimony, bismuth, vanadium, niobium, tantalum, polonium, chromium, molybdenum, tungsten, manganese, technetium or rhenium
• C25B 3/25 - Reduction

Abstract

The present invention relates to a novel composition of plant ingredients. A green process for the preparation of novel extracts that is rich in theanine, withanolides, polyphenols (Catechins, gallic acid, rutin, myricetin) and caffeine, etc. C. sinensis based extract was found and reported safe while aqueous extract of Withania somnifera leaves was found to be safe at 2000 mg/kg body weight when tested in rodents. The extracts were found to be stable up to 6 months at room temperature. Combination of extracts (1:3) i.e theanine enriched extract and aqueous extract of tea and ashwagandha were found to have sleep improvement properties such as better initiation and potentiation of sleep in terms of onset of sleep and number of sleep bouts.

IPC Classes  ?

• A61K 36/185 - Magnoliopsida (dicotyledons)
• A61K 47/38 - CelluloseDerivatives thereof
• A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
• A61K 47/02 - Inorganic compounds
• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives

Abstract

The present invention relates to process for halogenation of aromatic and/or heteroaromatic compounds with polymers derived from dihalogenated monomers or plastic waste products thereof as halide source under additive-free electrochemical conditions working in an undivided cell to produce halogenated aromatic and/or heteroaromatic compounds and/or dehalogenated polymers in a batch mode and/or a continuous flow mode. Further, present invention provides a process for the preparation of value-added products from the dehalogenated polymers by deconstructing and/or depolymerizing via cross-metathesis and other reactions.

IPC Classes  ?

• C08L 27/08 - Homopolymers or copolymers of vinylidene chloride
• C08F 8/20 - Halogenation
• C08F 8/50 - Partial depolymerisation
• C08F 8/26 - Removing halogen atoms or halogen-containing groups from the molecule

Abstract

The present invention relates to an anodic material for use in lithium ion battery (LIB) comprising of FeSe2 and its carbon composite with N, S doped porous carbon spheres (PNSCS) which can be synthesised by hydrothermal route using iron ammonium sulphate, selenium powder and citric acid as precursors and used as an anode for LIB. Further, the invention provides a process for synthesizing the said FeSe2 a PNSCS micro-flower composite by simple hydrothermal route.

IPC Classes  ?

• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• C01B 32/05 - Preparation or purification of carbon not covered by groups , , ,
• H01M 4/58 - Selection of substances as active materials, active masses, active liquids of inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFySelection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates
• H01M 4/587 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx for inserting or intercalating light metals
• H01M 50/109 - Primary casingsJackets or wrappings characterised by their shape or physical structure of button or coin shape

Abstract

22) production. The present invention also relates to a process for treatment of organic enriched wastewater to significantly reduce high concentrations of BOD and COD from effluent stream.

IPC Classes  ?

• C12M 1/107 - Apparatus for enzymology or microbiology with means for collecting fermentation gases, e.g. methane

Abstract

Gas bio-trickling filter (g-BTF) processes are provided for polluted air purification mainly focusing on the treatment of VOCs and odor using low-cost filter media (agricultural waste i.e., wood char coal and other waste i.e., sludge, compost etc.) that is cheap and readily available. Apparatus for purifying volatile organic compounds and odor control enriched air stream uses a consortium of the microorganisms including Rhodococus sp., Paracocus sp, Microbacterium sp., Mutant Paracocus denitrificans sp. The consortium approach ensures a broader range of VOC degradation capabilities, allowing for efficient removal of multiple compounds simultaneously. This versatility makes biotrickling filters highly adaptable to different industrial settings, such as paint manufacturing plants or automotive facilities. Compared to other process (thermal and chemical process), the developed BTF process are associated with the lowest operating and maintenance costs. Overall VOC and odor removal efficiency of the g-BTF unit is 99.9%.

IPC Classes  ?

• B01D 53/85 - Biological processes with gas-solid contact
• B01D 53/34 - Chemical or biological purification of waste gases
• B01D 53/96 - Regeneration, reactivation or recycling of reactants

Abstract

The present invention relates to engineered miniprotein mimics that exhibit binding patterns with SARS-COV-2 variant spike receptor binding domain (RBD) identical to that of ACE2. Further, the present invention relates to a process for recombinant expression and production of the engineered miniprotein mimics, and their uses thereof.

IPC Classes  ?

• C07K 14/705 - ReceptorsCell surface antigensCell surface determinants
• A61K 38/00 - Medicinal preparations containing peptides
• G16B 15/30 - Drug targeting using structural dataDocking or binding prediction
• G16B 35/00 - ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides

Abstract

The present invention relates to a continuous flow process for the synthesis of silver nanowire in the microwave. Specifically, the present invention relates to a process that uses a tubular reactor under microwave assisted conditions for synthesizing silver nanowires. Further, the process of the present invention is carried out in shorter reaction time with high yields and throughput.

IPC Classes  ?

• C01G 5/00 - Compounds of silver
• C08K 3/16 - Halogen-containing compounds
• C08J 3/28 - Treatment by wave energy or particle radiation
• C08K 3/10 - Metal compounds
• B82B 3/00 - Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
• B82Y 40/00 - Manufacture or treatment of nanostructures
• B22F 9/24 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using chemical processes with reduction of metal compounds starting from liquid metal compounds, e.g. solutions
• B01J 19/18 - Stationary reactors having moving elements inside
• B01J 19/20 - Stationary reactors having moving elements inside in the form of helices, e.g. screw reactors
• B01J 4/00 - Feed devicesFeed or outlet control devices

Abstract

The present invention discloses oxygen enriched air blown pressurized fluidized bed pilot scale refractory lined gasifier of 1.5 TPD feed capacity to gasify coal, biomass, washery rejects, and their blends in any proportion in the actual atmosphere of commercial gasifier. The system is equipped in such a way that it can be operated in air/oxygen/oxygen enriched air/steam as well as their mixture in any proportion as per process requirement. The present invention discloses gasifier having feed rate carrying capacity up to 60 kg/hour, maximum operating temperature up to 1050° C. and pressure up to 10 kg/cm2. The facility consists different sections for gaseous and solid feeding, gasification, ash withdrawal, and gas Cooling & Cleaning. Besides gasification performance analysis, present invention is also discloses the study of agglomeration characteristics, entrainment and other fluidized bed gasification related parameters.

IPC Classes  ?

• C10J 3/72 - Other features
• C10J 3/48 - ApparatusPlants
• C10J 3/82 - Gas withdrawal means

Abstract

The present invention discloses a biphasic Nitrogen doped sodiophilic anode. The present disclosure also provides a process of preparing a defect rich Nitrogen doped waste polymer derived carbon (PDC) and commercial polyvinyl based polymer derived carbon (PRC) as carbon precursor for use in sodium ion/metal battery with high capacity, long cyclic stability in both half cell and full cell.

IPC Classes  ?

• H01M 4/1393 - Processes of manufacture of electrodes based on carbonaceous material, e.g. graphite-intercalation compounds or CFx
• B09B 3/35 - Shredding, crushing or cutting
• B09B 3/40 - Destroying solid waste or transforming solid waste into something useful or harmless involving thermal treatment, e.g. evaporation
• B09B 101/75 - Plastic waste
• H01M 4/02 - Electrodes composed of, or comprising, active material
• H01M 4/04 - Processes of manufacture in general
• H01M 4/133 - Electrodes based on carbonaceous material, e.g. graphite-intercalation compounds or CFx
• H01M 4/58 - Selection of substances as active materials, active masses, active liquids of inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFySelection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates
• H01M 4/587 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx for inserting or intercalating light metals
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• H01M 10/0567 - Liquid materials characterised by the additives
• H01M 10/0568 - Liquid materials characterised by the solutes
• H01M 10/0569 - Liquid materials characterised by the solvents
• H01M 50/431 - Inorganic material
• H01M 50/44 - Fibrous material

Abstract

The invention provides a novel, economical and practical route for the synthesis of an ester from acid and alcoholic functionalities using Trihalotriazine as coupling agent. Specifically, the invention provides a novel, economical and practical route for the preparation of Nafamostat and Camostat. Synthesis of p-guanidinobenzoic acid (Al) was also achieved from thiourea and p-aminobenzoic acid by using trihalotriazine as coupling reagent.

IPC Classes  ?

• C07C 277/08 - Preparation of guanidine or its derivatives, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines

Abstract

The present invention relates to synthetic aromatic/monomeric compounds specifically bisguaiacol based compounds. The invention relates to a process for preparation of said Bisguaiacol-F based compounds of Formula I and/or one or more of Formula IA, Formula IB or Formula IC thereof, or stereoisomer, racemate, and pharmaceutically acceptable salts thereof. Further, the compounds prepared and disclosed herein are useful for production of water treatment membranes, biomedical devices, household products, automation component, fuel cell membrane, printed circuit board, and production of polymers such as polycarbonates, polyesters, polysufonates, and epoxy resins Formula(I).

IPC Classes  ?

• C07C 15/16 - Polycyclic non-condensed hydrocarbons containing at least two phenyl groups linked by one single acyclic carbon atom
• C07C 35/08 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic containing six-membered rings
• C07C 29/20 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds in six-membered aromatic rings in non-condensed rings substituted with hydroxy groups
• C07C 43/23 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups

Abstract

The present invention relates to a field of biopolymers and microbial fermentation. Specifically, the present invention relates to a microbial process for industrial production of a biopolymer. More particularly, the present invention relates to a process for synthesis of poly-γ-glutamic acid from maltose and sugarcane bagasse. The process of the present invention is devoid of pre- treating of raw materials (biomass) thereby eliminating environmental and cost concerns.

IPC Classes  ?

• C12N 1/20 - BacteriaCulture media therefor
• C12P 13/14 - Glutamic acidGlutamine
• C12R 1/07 - Bacillus

Abstract

The present invention relates to a heterogeneous catalyst for the synthesis of alkyl carbonates, comprising zinc-based mixed phases material having mixture of amorphous and crystalline porous particles of the catalyst, and with non-smooth, irregular/non-homogenous surface morphology. The invention also relates to a process of preparation of said zinc-based mixed phases heterogeneous catalyst. Further, the invention relates to a process of preparation of alkyl carbonates using said heterogeneous catalyst via a trans-esterification process.

IPC Classes  ?

• B01J 21/00 - Catalysts comprising the elements, oxides or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium or hafnium
• B01J 23/06 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of zinc, cadmium or mercury
• B01J 23/02 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the alkali- or alkaline earth metals or beryllium
• B01J 37/04 - Mixing
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties

Abstract

The present invention provides an improved method for the preparation of building blocks 2- (4-chlorophenyl)-2-hydroxy-N-(3-methoxy-4-(prop-2-yn-1-yloxy)phenethyl)acetamide, a key intermediate for the synthesis of Mandipropamid. An efficient, safe, cost-effective method for the preparation of Mandipropamid is developed. The method involves simple Nitro-aldol reaction, LAH reduction and mild Amidation reaction for synthesizing key intermediate 2-(4- chlorophenyl)-2-hydroxy-N-(3-methoxy-4-(prop-2-yn-1-yloxy)phenethyl)acetamide (E). The current synthesis method of the invention has relatively simple operation, mild reaction conditions, high yield and a simple process with, a yield up to 90%. Subsequent product purification of this method uses filtration and crystallization methods and easy column chromatography separation. This approach is highly effective and scalable, contributing to both atom and step economy in the process Therefore, the research of its synthetic process has a wide range of applications from the drug development and material synthesis point of view.

IPC Classes  ?

• C07C 237/20 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
• C07C 237/14 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated and containing rings
• C07C 59/56 - Unsaturated compounds containing hydroxy or O-metal groups containing halogen

Abstract

The present invention generally relates to fuel cells, specifically Proton Exchange Membrane Fuel Cell (PEMFC). The present invention relates to a composite material for coating electrode(s) or membrane in fuel cells comprising M1 metal nanoparticles dispersed or anchored over nitrogen doped 3D graphitic carbon; and a process of preparation thereof. Further, the present invention relates to a composition for fuel cells comprising effective amount or ratio of polymer based solid electrolyte and the composite material. The invention also relates to half PEM fuel cell and/or full PEM fuel cell comprising said composite material as coating layer onto electrode or membrane placed over/in between electrode(s).

IPC Classes  ?

• C23C 18/42 - Coating with noble metals
• C23C 18/48 - Coating with alloys
• C23C 18/50 - Coating with alloys with alloys based on iron, cobalt or nickel
• H01M 8/0223 - Composites
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites

Abstract

The present invention relates to phthalimidine-containing bisphenol monomers bearing pendant furyl group of Formula (I) and (co) polymers of Formula (II) obtained by polycondensation of varying mixtures of monomer of Formula (I) and bisphenol-A with aromatic diacid chlorides and the processes for the preparation thereof.

IPC Classes  ?

• C08G 63/685 - Polyesters containing atoms other than carbon, hydrogen, and oxygen containing nitrogen
• C07D 405/06 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Abstract

The present invention provides a continuous single step, solvent free and additive free process for the synthesis of Paracetamol with more than 90% conversion of the solid substrates and at least 94-97% selectivity towards paracetamol as product, and that to without the need of any solvent in a screw reactor.

IPC Classes  ?

• C07C 231/00 - Preparation of carboxylic acid amides
• C07C 213/08 - Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
• C07C 235/46 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
• C07C 233/25 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
• C07C 215/76 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton of the same non-condensed six-membered aromatic ring

Abstract

The present disclosure generally relates to synthetic heteroaromatic compounds specifically synthesis of natural based compounds via electrochemical mode. The present disclosure relates to (un)substituted bisindole based compound, stereoisomer, racemate or pharmaceutically acceptable salt and method for preparation thereof via electrochemical synthetic mode. More specifically, the present invention relates to preparation of Vibrindole A and related natural based compounds of formula I via electrochemical synthetic mode.

IPC Classes  ?

• C07D 487/04 - Ortho-condensed systems
• C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
• C07D 209/04 - IndolesHydrogenated indoles
• C07D 209/08 - IndolesHydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring

Abstract

The present invention relates to a heterogeneous photocatalyst system for partial oxidation of C1-C2 alkanes into value added products, comprising visible-light active semiconductor material (M1VO4) assembled and integrated onto a mesoporous metal oxide supported onto support, wherein said M1 has different or interchangeable mixed oxidation states. Further, the present invention relates to a process of preparation of said heterogeneous photocatalyst system by doctor blade method for preparation of mesoporous metal oxide supported onto support, followed by SILAR method for assembling and integrating visible-light active semiconductor material (M1VO4). Furthermore, the present invention relates to a process for conversion of lower alkane (e.g. C1-C2, and a mixture thereof) into value added products by reacting saturated aqueous alkane solution in presence of said heterogeneous photocatalyst system and simulated solar light condition or direct sunlight in a photoreactor.

IPC Classes  ?

• B01J 23/10 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of rare earths
• B01J 23/44 - Palladium
• B01J 21/06 - Silicon, titanium, zirconium or hafniumOxides or hydroxides thereof
• B01J 23/06 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of zinc, cadmium or mercury

Abstract

The present invention provides a technical solution in the form of a machine learning (ML) based system and a machine learning (ML) based method to predict a Pressure-Composition-Temperature (PCT) curve for a metal alloy to be used/implemented for solid-state hydrogen storage. The instant invention aims to solve the problems associated with determining the suitability of an alloy for solid state hydrogen storage, specifically by predicting the PCT curve that enables to determine the suitability of an alloy for solid state hydrogen storage, Accordingly, aspects of the present invention relate to a system and methods to analyze, predict and generate PCT (pressure-composition- temperature) curves for metal alloys w.r.t storage of H2 in solid-state, the system and methods provided herein predict such details using machine learning based mode.

IPC Classes  ?

• G06N 20/00 - Machine learning
• G16C 20/70 - Machine learning, data mining or chemometrics
• G16C 60/00 - Computational materials science, i.e. ICT specially adapted for investigating the physical or chemical properties of materials or phenomena associated with their design, synthesis, processing, characterisation or utilisation
• G16C 20/30 - Prediction of properties of chemical compounds, compositions or mixtures

Abstract

The present disclosure generally relates to polymer or crosslinkers useful in effective 3D printing. The invention relates to an acrylated polyvinyl-grafted-poly(l-lactide) (acr. PVAc-g- PLLA) polymer of formula I to act as a crosslinker in a composition for printing 3D products and process for the preparation and application in 3D printing composition thereof.

IPC Classes  ?

• B33Y 80/00 - Products made by additive manufacturing
• B33Y 70/10 - Composites of different types of material, e.g. mixtures of ceramics and polymers or mixtures of metals and biomaterials
• B33Y 70/00 - Materials specially adapted for additive manufacturing