Disclosed are various examples and embodiments of systems, devices, components and methods configured to provide enhanced resolution electrographic flow (EGF) spatial maps of a patient's heart, and subsequently to detect at least one location or type of at least one source, rotational phenomenon, or slow electrical conduction zone or area associated with at least one cardiac rhythm disorder within such maps. Data acquired using intracardiac electrodes and/or body surface electrodes are used in conjunction with EGF techniques to generate an enhanced resolution map corresponding to a spatial map. The enhanced resolution map is configured to reveal on a monitor or display to a user the at least one location or type of the at least one source, rotational phenomenon, or slow electrical conduction zone or area associated with at least one cardiac rhythm disorder.
A61B 5/352 - Detecting R peaks, e.g. for synchronising diagnostic apparatusEstimating R-R interval
2.
Systems, Devices, Components and Methods for Detecting the Locations of Sources of Cardiac Rhythm Disorders in a Patient's Heart Using Improved Electrographic Flow (EGF) Methods
Disclosed are various examples and embodiments of systems, devices, components and methods configured to estimate the action potential wave propagation in a patient's heart, and subsequently to detect at least one location or type of at least one source of, or rotational phenomenon associated with, at least one cardiac rhythm disorder using intracardiac electrodes and a modified multi-frame Horn-Schunck algorithm to generate a map corresponding to a spatial map, the map being configured to reveal on a monitor or display to a user the at least one location of the at least one source of the at least one cardiac rhythm disorder.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Downloadable medical software for mapping cardiac activity. Medical devices used for mapping cardiac activity; Computerized medical recording and analysis apparatus for the diagnosis and treatment of arrhythmias and other cardiac abnormalities comprised of electrophysiology catheters, sensors, amplifiers, computer hardware, displays, monitors and computer accessories therefor in the nature of workstations, carts, cables, power cords, keyboards, mouses all for use in diagnostic procedures; cardiac catheters; medical diagnostic instruments. Providing temporary use of online non-downloadable medical software for mapping cardiac activity.
4.
Systems, Devices, Components and Methods for Detecting the Locations of Sources of Cardiac Rhythm Disorders in a Patient's Heart
Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals are acquired from inside a patient's heart, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional (2D) spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals to generate a plurality of three-dimensional electrogram surfaces corresponding at least partially to the 2 D grid, one surface being generated for each of selected discrete times, and processing the plurality of three-dimensional electrogram surfaces through time to generate a velocity vector map corresponding at least partially to the 2 D grid. The resulting velocity vector map is configured to reveal the location of the source of the at least one cardiac rhythm disorder, which may be, by way of example, an active rotor in a patient's myocardium and atrium.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Downloadable medical software for mapping cardiac activity Medical devices used for mapping cardiac activity; Computerized medical recording and analysis apparatus for the diagnosis and treatment of arrhythmias and other cardiac abnormalities comprised of electrophysiology catheters, sensors, amplifiers, computer hardware, displays, monitors and computer accessories therefor in the nature of workstations, carts, cables, power cords, keyboards, mouses all for use in diagnostic procedures Providing temporary use of online non-downloadable medical software for mapping cardiac activity
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Electrical cables and wires medical diagnostic apparatus for treating cardiovascular disease, incorporating recorded preinstalled software for mapping cardiac activity; Medical apparatus and instruments for treating cardiovascular disease; Surgical apparatus and instruments; Medical instruments for cardiovascular diagnostics; Medical electrodes; Electrocardiographs; Catheters; Cardiac probes; Ablation catheters; Diagnostic catheters; Basket catheters for collecting intracardiac signals; Medical devices used for mapping cardiac anatomy and activity; Computerized medical recording and analysis apparatus for the diagnosis and treatment of arrhythmias and other cardiac abnormalities comprised of electrophysiology catheters, sensors, amplifiers, and computer hardware, all for use in diagnostic and interventional procedures; Medical devices, namely, pulsed electric field generators that generate energy to drive ablation catheters and connection cables for use with such generators; none of the aforesaid in the field of integrated circuits, microprocessors, microprocessor cores Providing temporary use of online non-downloadable medical software for mapping cardiac activity; Design of apparatus and instruments for treating cardiac arrythmias; Research and development in the field of cardiac catheters; Industrial research in the field of apparatus and instruments for treating cardiac arrythmias; none of the aforesaid in the field of integrated circuits, microprocessors, microprocessor cores
7.
Systems, Devices, Components and Methods for Electroanatomical Mapping of the Heart Using 3D Reconstructions Derived from Biosignals
In some embodiments, there are provided systems, devices, components, and corresponding methods configured to permit navigation and/or positioning of an intra-cardiac electrophysiological (EP) mapping basket or other EP mapping structure of an EP mapping catheter inside or near an atrium or other heart chamber of a patient's heart using biosignals or intra-cardiac signals. In one embodiment, QRS complexes are extracted or isolated from intra-cardiac signals sensed by electrodes mounted on the EP mapping basket. Using the QRS complexes and a statistical shape or other model of the EP mapping basket or other type of EP mapping structure, one or more computing devices then determine the locations of the electrodes inside or near the patient's atrium that are associated with each isolated or extracted QRS complex, and thereby permit accurate navigation within the heart and/or processing of data acquired using the EP mapping basket or other EP mapping structure. The one or more computing devices can also be used to determine changes in the three-dimensional locations and orientations of the basket and the electrodes thereof as the EP mapping basket is moved around, in, or near the patient's atrium, heart chamber, or other portion of the patient's heart, and to display to a user multiple positions of the basket inside or near the patient's heart.
Disclosed are various examples and embodiments of systems, devices, components and methods configured to extract atrial signals from electrical signals acquired from a patient suffering from atrial fibrillation. The electrical signals acquired from the patient may be intra-cardiac signals or body surface electrode signals, or both. At least portions of QRS or QRS-T complexes corresponding to determined initial synchronization times are used to generate Fast Fourier Transforms (FFTs) corresponding to the extracted QRS complexes. A series of steps follow to generate isolated atrial signals corresponding to each electrical signal by subtracting generated reconstructed signals corresponding to each such electrical signal therefrom.
A61B 5/366 - Detecting abnormal QRS complex, e.g. widening
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
9.
Systems, devices, components and methods for detecting the locations of sources of cardiac rhythm disorders in a patient's heart using improved electrographic flow (EGF) methods
Disclosed are various examples and embodiments of systems, devices, components and methods configured to estimate the action potential wave propagation in a patient's heart, and subsequently to detect at least one location or type of at least one source of, or rotational phenomenon associated with, at least one cardiac rhythm disorder using intracardiac electrodes and a modified multi-frame Horn-Schunck algorithm to generate a map corresponding to a spatial map, the map being configured to reveal on a monitor or display to a user the at least one location of the at least one source of the at least one cardiac rhythm disorder.
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
10.
Nitinol Basket for Electrophysiological Mapping Catheter, and Systems, Devices, Components and Methods Associated Therewith
Disclosed are various examples and embodiments of a Nitinol basket for an electrophysiological (EP) mapping catheter. In one embodiment, the Nitinol basket comprises a plurality of basket splines, each basket spline having a distalmost portion and a proximal end, where the distal tip is uninterruptedly contiguous and continuous with the distalmost portions of the basket splines and formed from the same piece, slab or ingot comprising Nitinol as the splines. In such an embodiment, the basket splines and distal tip are cut and formed from a same single length or piece of Nitinol tubing or a Nitinol hypotube. The respective distal portions of each of the Nitinol splines can be continuous and contiguous with, and connected to, the Nitinol distal tip, each spline being configured to extend outwardly away from an imaginary central axis of the Nitinol basket and its proximal end and distal portion to form a curved shape therebetween when the Nitinol basket is in an undeformed and deployed state. The splines can be configured to be spaced approximately equal distances apart from one another when the Nitinol basket is in an undeformed and deployed state, and the can be configured collectively to form a basket shape when the Nitinol basket is in an undeformed, expanded and deployed state.
In some embodiments, there are provided systems, devices, components, and corresponding methods configured to permit navigation and or positioning of an intra-cardiac electrophysiological (EP) mapping basket of an EP mapping catheter inside or near an atrium or other heart chamber of a patient's heart using biosignals or intra-cardiac signals. In one embodiment, QRS complexes are extracted or isolated from intra-cardiac signals sensed by electrodes mounted on the EP mapping basket. Using the QRS complexes, one or more computing devices then determine the locations of the electrodes inside or near the patient's atrium that are associated with each isolated or extracted QRS complex. The one or more computing devices can also be used to determine changes in the three-dimensional locations and orientations of the basket and the electrodes thereof as the basket is moved around, in, or near the patient's atrium, heart chamber, or other portion of the patient's heart. The computing device can also be configured to use position change detection methods to detect basket catheter movements inside or near the patient's heart, determine the three-dimensional coordinates X of each electrode for a given position and orientation of the basket within the patient's heart, determine and display to a user multiple positions of the basket inside or near the patient's heart, and provide a visual display to a user of the locations of the electrodes and/or basket inside or near the patient's heart.
Systems, Devices, Components and Methods for Detecting the Locations of Sources of Cardiac Rhythm Disorders in a Patient's Heart Using Body Surface Electrodes and/or Cardiac Monitoring Patches
Disclosed are various examples and embodiments of systems, devices, components and methods configured to classify, and to detect at least one location or type of at least one source of, at least one cardiac rhythm disorder in a patient's heart using one or more body surface electrodes, and/or intracardiac electrodes. Body surface electrogram data, and optionally intracardiac electrode data, representative of cardiac signals acquired from the patient are provided to a computing device, which in turn determines the location and type of the at least one source of the at least one cardiac rhythm disorder in the patient's heart using electrographic flow (EGF) methods, and then classifies same using electrographic volatility index (EVI) methods.
Systems, Devices, Components and Methods for Detecting the Locations of Sources of Cardiac Rhythm Disorders in a Patient's Heart and Generating an Estimate or Probability of the Patient Being Free from Atrial Fibrillation
Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect the locations of sources of cardiac rhythm disorders in a patient's heart, and then to generate an estimate or probability of the patient being free from atrial fibrillation. The various embodiments employ at least one computing device to process a plurality of electrogram surfaces through time to generate at least one electrographical flow (EGF) map, representation, pattern, or data set, and then process the at least one EGF map, representation, pattern, or data set to determine at least two of source activity levels, flow angle variability (FAV) levels, and active fractionation (AFR) levels corresponding thereto. On the basis of a combination of the determined at least two of source activity levels, FAV levels, and AFR levels, an electrographical volatility index (EVI) score or metric representative of the estimate or probability of the patient being free from AF is generated.
(a, b, c, d, e or f) coordinates, wherein for assigning each 3D scan data point to one of the 6 directions (a, b, c, d, e or f) the following 6 true or false tests are applied: Formula (I), wherein max indicates the maximum leg length of the respective X, Y or Z axis and wherein mes indicates the measured value of a scanned data point, and wherein the data point is assigned to the direction (a, b, c, d, e or f) for which the test outcome is true.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Downloadable medical software for mapping cardiac activity. Medical devices used for mapping cardiac activity; computerized medical recording and analysis apparatus for the diagnosis and treatment of arrhythmias and other cardiac abnormalities, namely, electrophysiology catheters, sensors, amplifiers, computer hardware, displays, monitors and computer accessories therefor, namely, workstations, carts, cables, power cords, keyboards, mouses, all for use in diagnostic procedures. Providing online, non-downloadable, medical software for mapping cardiac activity.
17.
Methods, systems, devices, and components for visualizing electrographic flow (EGF)
Electrographic flow mapping (EGF mapping) is a technique used for aiding catheter ablation when treating atrial fibrillation. Visualizing EGF fields during a cardiac catherization and ablation procedure is an important and necessary part of conducting the procedure. Several different visualization methods are described and disclosed herein that may be employed to visualize EGF fields and maps, including quiver plots, streamline plots, particle plots, particle trail plots, moving particle plots, and moving and fading particle plots.
A61B 5/364 - Detecting abnormal ECG interval, e.g. extrasystoles or ectopic heartbeats
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 34/20 - Surgical navigation systemsDevices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Downloadable medical software for mapping cardiac activity Providing temporary use of online non-downloadable medical software for mapping cardiac activity
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Downloadable medical software for mapping cardiac activity Medical devices used for mapping cardiac activity; Computerized medical recording and analysis apparatus for the diagnosis and treatment of arrhythmias and other cardiac abnormalities comprised of electrophysiology catheters, sensors, amplifiers, computer hardware, displays, monitors and computer accessories therefor in the nature of workstations, carts, cables, power cords, keyboards, mouses all for use in diagnostic procedures Providing temporary use of online non-downloadable medical software for mapping cardiac activity
20.
Systems, devices, components and methods for detecting the locations of sources of cardiac rhythm disorders in a patient's heart
Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals are acquired from a patient's body surface, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals to generate a plurality of three-dimensional electrogram surfaces corresponding at least partially to the 2D map, one surface being generated for each or selected discrete times, and processing the plurality of three-dimensional electrogram surfaces through time to generate a velocity vector or other type of map using one or more of optical flow, video tracking analysis, motion capture analysis, motion estimation analysis, data association and segmentation tracking analysis, particle tracking analysis, and single-particle tracking analysis methods corresponding at least partially to the 2D map. Trained atrial discriminative machine learning models that facilitate the foregoing systems and methods, and that provide predictions or results concerning a patient's condition, are also disclosed.
Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals are acquired from a patient's body surface, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals to generate a plurality of three-dimensional electrogram surfaces corresponding at least partially to the 2D map, one surface being generated for each or selected discrete times, and processing the plurality of three-dimensional electrogram surfaces through time to generate a velocity vector map corresponding at least partially to the 2D map. The resulting velocity vector map maybe employed to classify a patient as one of an A-type patient, a B-type patient, and a C-type patient, and to guide therapy subsequently delivered to the patient. Trained atrial discriminative machine learning models that facilitate the foregoing systems and methods, and that provide predictions or results concerning a patient's condition, are also disclosed.
A61B 5/367 - Electrophysiological study [EPS], e.g. electrical activation mapping or electro-anatomical mapping
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/0285 - Measuring phase velocity of blood waves
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
Disclosed are various examples and embodiments of a cardiac mapping catheter configured for electrophysiological (EP) mapping and suitable for intravascular insertion in a patient's heart, and methods of making same. The cardiac mapping catheter comprises a plurality support arms having electrodes disposed thereon. Various configurations of the cardiac mapping catheter are described and disclosed which provide improved spatial resolution and sensing of EP signals acquired from inside a patient's heart.
Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart, such as atrial fibrillation, and to classify same. Velocity vector maps reveal the location of the source of the at least one cardiac rhythm disorder in the patient's heart, which may be, by way of example, an active rotor in the patient's myocardium and atrium. The resulting velocity vector map may be further processed and/or analyzed to classify the nature of the patient's cardiac rhythm disorder, e.g., as Type A, B or C atrial fibrillation. The resulting cardiac rhythm classification then can be used to determine the optimal, most efficacious and/or most economic treatment or surgical procedure that should be provided to the individual patient. A simple and computationally efficient intra-cardiac catheter-based navigation system is also described. Also described and disclosed are various intra-cardiac catheter-based navigation systems.
Disclosed are various examples of embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals are acquired from inside a patient's heart, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional (2D) spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals to generate a plurality of three-dimensional electrogram surfaces corresponding at least partially to the 2 D grid, one surface being generated for each or selected discrete times, and processing the plurality of three-dimensional electrogram surfaces through time to generate a velocity vector map corresponding at least partially to the 2 D grid. The resulting velocity vector map is configured to reveal the location of the source of the at least one cardiac rhythm disorder, which may be, by way of example, an active rotor in a patient's myocardium and atrium.
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
25.
Systems, devices, components and methods for detecting the locations of sources of cardiac rhythm disorders in a patient?s heart and classifying SaCL
Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart, such as atrial fibrillation, and to classify same. Velocity vector maps reveal the location of the source of the at least one cardiac rhythm disorder in the patient's heart, which may be, by way of example, an active rotor in the patient's myocardium and atrium. The resulting velocity vector map may be further processed and/or analyzed to classify the nature of the patient's cardiac rhythm disorder, e.g., as Type A, B or C atrial fibrillation. The resulting cardiac rhythm classification then can be used to determine the optimal, most efficacious and/or most economic treatment or surgical procedure that should be provided to the individual patient. A simple and computationally efficient intra-cardiac catheter-based navigation system is also described.
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
26.
Systems, devices, components and methods for detecting the locations of sources of cardiac rhythm disorders in a patient's heart
Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals are acquired from inside a patient's heart, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals across the 2D representation to generate a plurality of three-dimensional electrogram surfaces, one surface being generated for each or selected discrete times, and processing the plurality of three-dimensional electrogram surfaces across the 2D map through time to generate a velocity vector map. The resulting velocity vector map is configured to reveal the location of the source of the at least one cardiac rhythm disorder, which may be, by way of example, an active rotor in a patient's myocardium and atrium.
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
27.
System for analyzing electrophysiological data and method for analyzing electrophysiological data
The present invention concerns a system (100) for analyzing electrophysiological data, especially intracardial electrogram data, the system (100) comprising a data processing and control unit (15) for processing the electrophysiological data, a data output unit comprising a data output screen (324) for displaying results of electrophysiological data analysis, wherein the data processing and control unit (15) being configured to receive electrophysiological data obtained from a mapping catheter assembly (110, 111) that comprises an electrode assembly (120, 80) with a plurality of n electrodes (82), each electrode (82) configured for measuring electrophysiological data in the form of electrogram signals. The data processing and control unit (15) comprises an engine for performing an optical flow analysis of the electrophysiological data to generate series of vector data (40) representing the average speed and direction of movement of clusters of the electrophysiological data, the data output unit being configured to display the vector data on a data output screen (324) of the data output unit.
1) to the light source along the optical sensor axis (B), a mounting assembly (50) for the optical sensor (40) and the light source (30) which allows for relative movement of the light source (30) against the optical sensor (40) at least in the directions X, Y, Z of the Cartesian coordinate system, wherein direction Z is parallel to the direction of the optical sensor axis (B) at least in an initial state of the optical force sensing assembly (20) and whereby X and Y directions are perpendicular to each other as well as perpendicular to Z direction.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
G01L 5/166 - Apparatus for, or methods of, measuring force, work, mechanical power, or torque, specially adapted for specific purposes for measuring several components of force using photoelectric means
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 17/00 - Surgical instruments, devices or methods
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
Disclosed are various examples and embodiments of a cardiac mapping catheter configured for electrophysiological (EP) mapping and suitable for intravascular insertion in a patient's heart, and methods of making same. The cardiac mapping catheter comprises a plurality support arms having electrodes disposed thereon. Various configurations of the cardiac mapping catheter are described and disclosed which provide improved spatial resolution and sensing of EP signals acquired from inside a patient's heart.
Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals are acquired from inside a patient's heart, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional (2D) spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals to generate a plurality of three-dimensional electrogram surfaces corresponding at least partially to the 2 D grid, one surface being generated for each or selected discrete times, and processing the plurality of three-dimensional electrogram surfaces through time to generate a velocity vector map corresponding at least partially to the 2 D grid. The resulting velocity vector map is configured to reveal the location of the source of the at least one cardiac rhythm disorder, which may be, by way of example, an active rotor in a patient's myocardium and atrium.
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
31.
Systems, devices, components and methods for detecting the locations of sources of cardiac rhythm disorders in a patient's heart
Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals are acquired from inside a patient's heart, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals to generate a plurality of three-dimensional electrogram surfaces corresponding at least partially to the 2D map, one surface being generated for each or selected discrete times, and processing the plurality of three-dimensional electrogram surfaces through time to generate a velocity vector map corresponding at least partially to the 2D map. The resulting velocity vector map is configured to reveal the location of the source of the at least one cardiac rhythm disorder, which may be, by way of example, an active rotor in a patient's myocardium and atrium.
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical and medicinal apparatus and Instruments,
particularly for applications in the field of cardiology;
surgical apparatus and instruments; defibrillators;
diagnostic apparatus for medical use; electrodes for medical
use; electrocardiographs; electro-therapeutic equipment;
catheters, particularly cardiac catheters; cardiac catheters
with sclerotherapy function; electric catheters; endoscopes
or probes for medical use, particularly for use in
cardiology; medical guide wires, particularly for
applications in the field of cardiology; stents; heart
pacemakers. Scientific and technological services as well as research
and design relating thereto; research in the field of
development of cardiac catheters; industrial analysis and
research services; design and development of computer
hardware and software. Conducting of medical and clinical examinations,
particularly cardiology testing; nursing homes, particularly
cardiological treatment of patients; services provided by a
doctor, particularly a cardiologist; medical laboratory
services.
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical and medicinal apparatus and Instruments,
particularly for applications in the field of cardiology;
surgical apparatus and instruments; defibrillators;
diagnostic apparatus for medical use; electrodes for medical
use; electrocardiographs; electro-therapeutic equipment;
catheters, particularly cardiac catheters; cardiac catheters
with sclerotherapy function; electric catheters; endoscopes
or probes for medical use, particularly for use in
cardiology; medical guide wires, particularly for
applications in the field of cardiology; stents; heart
pacemakers. Scientific and technological services as well as research
and design relating thereto; research in the field of
development of cardiac catheters; industrial analysis and
research services; design and development of computer
hardware and software. Conducting of medical and clinical examinations,
particularly cardiology testing; nursing homes, particularly
cardiological treatment of patients; services provided by a
doctor, particularly a cardiologist; medical laboratory
services.
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical and medicinal apparatus and Instruments,
particularly for applications in the field of cardiology;
surgical apparatus and instruments; defibrillators;
diagnostic apparatus for medical use; electrodes for medical
use; electrocardiographs; electro-therapeutic equipment;
catheters, particularly cardiac catheters; cardiac catheters
with sclerotherapy function; electric catheters; endoscopes
or probes for medical use, particularly for use in
cardiology; medical guide wires, particularly for
applications in the field of cardiology; stents; heart
pacemakers. Scientific and technological services as well as research
and design relating thereto; research in the field of
development of cardiac catheters; industrial analysis and
research services; design and development of computer
hardware and software. Conducting of medical and clinical examinations,
particularly cardiology testing; nursing homes, particularly
cardiological treatment of patients; services provided by a
doctor, particularly a cardiologist; medical laboratory
services.
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical and medicinal apparatus and Instruments,
particularly for applications in the field of cardiology;
surgical apparatus and instruments; defibrillators;
diagnostic apparatus for medical use; electrodes for medical
use; electrocardiographs; electro-therapeutic equipment;
catheters, particularly cardiac catheters; cardiac catheters
with sclerotherapy function; electric catheters; endoscopes
or probes for medical use, particularly for use in
cardiology; medical guide wires, particularly for
applications in the field of cardiology; stents; heart
pacemakers. Scientific and technological services as well as research
and design relating thereto; research in the field of
development of cardiac catheters; industrial analysis and
research services; design and development of computer
hardware and software. Conducting of medical and clinical examinations,
particularly cardiology testing; nursing homes, particularly
cardiological treatment of patients; services provided by a
doctor, particularly a cardiologist; medical laboratory
services.
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical instruments and apparatus, In particular for use in the cardiology sector; Surgical apparatus and instruments; Defibrillators; Diagnostic apparatus for medical purposes; Electrodes for medical use; Electrocardiographs; Electrotherapeutic equipment; Catheters, In particular cardiac catheters; Cardiac catheters with a sclerotherapy function; Electrocatheters; Endoscopes or probes for medical purposes, in particular for cardiological purposes; Medical guidewires, In particular for use in the cardiology sector; Stents; Cardiac stimulators. Scientific and technological services and research and design relating thereto; Research in the field of cardiac catheter development; Industrial analysis and research services; Design and development of computer hardware and software; Services of a medical laboratory. Conducting of medical and clinical examinations, in particular cardiological examinations; Nursing homes, In particular cardiological treatment of patients; Medical assistance, in particular cardiological assistance.
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical instruments and apparatus, In particular for use in the cardiology sector; Surgical apparatus and instruments; Defibrillators; Diagnostic apparatus for medical purposes; Electrodes for medical use; Electrocardiographs; Electrotherapeutic equipment; Catheters, In particular cardiac catheters; Cardiac catheters with a sclerotherapy function; Electrocatheters; Endoscopes or probes for medical purposes, in particular for cardiological purposes; Medical guidewires, In particular for use in the cardiology sector; Stents; Cardiac stimulators. Scientific and technological services and research and design relating thereto; Research in the field of cardiac catheter development; Industrial analysis and research services; Design and development of computer hardware and software; Services of a medical laboratory. Conducting of medical and clinical examinations, in particular cardiological examinations; Nursing homes, In particular cardiological treatment of patients; Medical assistance, in particular cardiological assistance.
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical instruments and apparatus, In particular for use in the cardiology sector; Surgical apparatus and instruments; Defibrillators; Diagnostic apparatus for medical purposes; Electrodes for medical use; Electrocardiographs; Electrotherapeutic equipment; Catheters, In particular cardiac catheters; Cardiac catheters with a sclerotherapy function; Electrocatheters; Endoscopes or probes for medical purposes, in particular for cardiological purposes; Medical guidewires, In particular for use in the cardiology sector; Stents; Cardiac stimulators. Scientific and technological services and research and design relating thereto; Research in the field of cardiac catheter development; Industrial analysis and research services; Design and development of computer hardware and software; Services of a medical laboratory. Conducting of medical and clinical examinations, in particular cardiological examinations; Nursing homes, In particular cardiological treatment of patients; Medical assistance, in particular cardiological assistance.
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical instruments and apparatus, In particular for use in the cardiology sector; Surgical apparatus and instruments; Defibrillators; Diagnostic apparatus for medical purposes; Electrodes for medical use; Electrocardiographs; Electrotherapeutic equipment; Catheters, In particular cardiac catheters; Cardiac catheters with a sclerotherapy function; Electrocatheters; Endoscopes or probes for medical purposes, in particular for cardiological purposes; Medical guidewires, In particular for use in the cardiology sector; Stents; Cardiac stimulators. Scientific and technological services and research and design relating thereto; Research in the field of cardiac catheter development; Industrial analysis and research services; Design and development of computer hardware and software; Services of a medical laboratory. Conducting of medical and clinical examinations, in particular cardiological examinations; Nursing homes, In particular cardiological treatment of patients; Medical assistance, in particular cardiological assistance.
