Abstract

Disclosed herein is an instrument and associated methods for a fully automated bench-top NULISA platform, comprising an X-Y-Z-gantry, a microtiter plate stage, an incubator, a quantitative PCR module, a decontamination cleaner for microtiter plates, a microtiter plate sealer, a magnetic probe and comb assembly for sample mixing and magnetic bead extraction, a storage unit for reagents and supplies, and a controller.

IPC Classes  ?

• G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
• G01N 35/04 - Details of the conveyor system

Abstract

Disclosed herein is an instrument and associated methods for a fully automated bench-top NULISA platform, comprising an X-Y-Z-gantry, a microtiter plate stage, an incubator, a quantitative PCR module, a decontamination cleaner for microtiter plates, a microtiter plate sealer, a magnetic probe and comb assembly for sample mixing and magnetic bead extraction, a storage unit for reagents and supplies, and a controller.

IPC Classes  ?

• G06Q 10/10 - Office automationTime management
• G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
• G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
• B01L 9/06 - Test-tube standsTest-tube holders
• F24F 11/30 - Control or safety arrangements for purposes related to the operation of the system, e.g. for safety or monitoring
• G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
• G06K 7/14 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation using light without selection of wavelength, e.g. sensing reflected white light

Abstract

The present invention is directed to systems, methods, and apparatus for an improved microfluidic cell imaging system that allows for the simultaneous application of a compression force to a biological specimen forming a consistent cell monolayer while imaging the cells.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers

Abstract

A waveguide optical gyroscope includes a multilayer waveguide rotation sensor fabricated on a substrate. The multilayer waveguide rotation sensor includes one or more overlaying non-intersecting, spiraling coils that are vertically separated to reduce or eliminate optical cross coupling. The waveguides are optically coupled by a vertical waveguide and are optically coupled to the other components of the optical gyroscope, including a light source and detector, which may be integrated or fabricated on the substrate. A lithium niobate phase modulator chip may be disposed on the substrate and optically coupled to the waveguides in the multilayer waveguide rotation sensor. The multilayer waveguide rotation sensor enables a small cross section for the guiding channels thereby achieving a high coil density in a small volume.

IPC Classes  ?

• G01C 19/72 - Gyrometers using the Sagnac effect, i.e. rotation-induced shifts between counter-rotating electromagnetic beams with counter-rotating light beams in a passive ring, e.g. fibre laser gyrometers
• G01C 19/64 - Gyrometers using the Sagnac effect, i.e. rotation-induced shifts between counter-rotating electromagnetic beams

Abstract

A waveguide optical gyroscope includes a multilayer waveguide rotation sensor fabricated on a substrate. The multilayer waveguide rotation sensor includes one or more overlaying non-intersecting, spiraling coils that are vertically separated to reduce or eliminate optical cross coupling. The waveguides are optically coupled by a vertical waveguide and are optically coupled to the other components of the optical gyroscope, including a light source and detector, which may be integrated or fabricated on the substrate. A lithium niobate phase modulator chip may be disposed on the substrate and optically coupled to the waveguides in the multilayer waveguide rotation sensor. The multilayer waveguide rotation sensor enables a small cross section for the guiding channels thereby achieving a high coil density in a small volume.

IPC Classes  ?

• G01C 19/64 - Gyrometers using the Sagnac effect, i.e. rotation-induced shifts between counter-rotating electromagnetic beams