Abstract

The present invention refers to a plant or plant part comprising a polynucleotide encoding an herbicide tolerant IAA2 polypeptide having a deleted or disrupted degron tail region, the expression of said polynucleotide confers to the plant or plant part tolerance to synthetic auxin herbicides, such as 2,4-D. The present invention relates to methods and plants and that have a deleted or disrupted degron tail region of the IAA2 protein obtained by gene editing, transformation, mutagenesis, breeding, and the like.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants
• C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae

Abstract

An upflow leach bed reactor configured to contain a substrate is provided. The reactor includes a container comprising a floor and a sidewall and configured to contain the substrate. The reactor further includes a fluid injection system including a plurality of fluid inlet ports arranged in an array across the floor. The fluid inlet ports can be moved between a first position below the substrate and a second position at least partially within the substrate. The reactor can also include a vertical drain extending from the top to the floor, between the substrate and the sidewall, and configured to permit downward liquid flow and inhibit upward liquid flow therethrough. The reactor can further include an inflatable bladder positioned adjacent the top of the container and configured to press downward against a top surface of the substrate.

IPC Classes  ?

• B09B 3/65 - Anaerobic treatment
• B09B 101/05 - VehiclesVehicle parts

Abstract

The present disclosure relates to polymers having Structure (I), The present disclosure relates to polymers having Structure (I), The present disclosure relates to polymers having Structure (I), where m is between 8 and 20, n is between 2 and 5,000, and is a covalent bond, methods of making the polymer, compositions that include the polymer, and methods of using the compositions.

IPC Classes  ?

• C08G 63/08 - Lactones or lactides
• C08J 5/18 - Manufacture of films or sheets

Abstract

Images of smoke captured over a time duration are obtained, and temporal and spatial features of the images are extracted. The temporal features are representative of changes across the images and the spatial features are representative of texture and color in the images. The temporal and spatial features are combined, with the combined temporal and spatial features being representative of both static appearance and dynamic motion of smoke in the images. The combined temporal and spatial features are used to determine the opacity of smoke in the images.

IPC Classes  ?

• G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
• G06T 7/70 - Determining position or orientation of objects or cameras
• G06T 7/90 - Determination of colour characteristics
• G08B 17/10 - Actuation by presence of smoke or gases
• G01N 21/53 - Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
• G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
• G06T 7/00 - Image analysis
• G06N 3/02 - Neural networks
• G06N 20/00 - Machine learning
• H04N 7/18 - Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast

Abstract

Systems and methods for identifying mental stress in a user is provided herein. Radar data is received that was acquired from a radar sensor. The radar data contains interference. A set of non-interference data clusters associated with the radar data is determined. A set of interference data clusters associated with the radar data is determined. The set of interference data clusters is removed from the radar data. A restored set of radar data clusters is created from the set of interference data clusters, using the set of non-interference clusters. A restored radar image is generated by combining the restored data clusters and the set of non-interference data clusters.

IPC Classes  ?

• G01S 13/00 - Systems using the reflection or reradiation of radio waves, e.g. radar systemsAnalogous systems using reflection or reradiation of waves whose nature or wavelength is irrelevant or unspecified
• G01S 19/21 - Interference related issues
• G01S 7/36 - Means for anti-jamming
• H04B 1/10 - Means associated with receiver for limiting or suppressing noise or interference
• G01S 13/34 - Systems for measuring distance only using transmission of continuous waves, whether amplitude-, frequency-, or phase-modulated, or unmodulated using transmission of continuous, frequency-modulated waves while heterodyning the received signal, or a signal derived therefrom, with a locally-generated signal related to the contemporaneously transmitted signal

Abstract

The present disclosure relates to certain fluorinated compounds, pharmaceutical compositions containing them, and methods of making and using them.

IPC Classes  ?

• C07D 311/80 - DibenzopyransHydrogenated dibenzopyrans
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• A61P 35/00 - Antineoplastic agents

Abstract

A power plant system is disclosed. The power plant system includes a combustor, a turbine configured to generate electricity, a carbon capture system configured to remove at least a portion of carbon-based gasses from the flue gas downstream from the combustor, and a thermal storage system including a hot storage unit configured to store heat generated at least by resistively-heated gas at a hot temperature, the hot temperature greater than ambient temperature. The power plant is configured to operate in at least a first mode for storing thermal energy in the thermal storage system and a second mode for releasing the stored thermal energy from the thermal storage system and during the second mode, heat stored in the hot storage unit is transferred to the carbon capture system.

IPC Classes  ?

• F01K 3/12 - Plants characterised by the use of steam or heat accumulators, or intermediate steam heaters, therein having two or more accumulators
• F01K 17/02 - Use of steam or condensate extracted or exhausted from steam engine plant for heating purposes, e.g. industrial, domestic
• F01K 23/10 - Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids the engine cycles being thermally coupled combustion heat from one cycle heating the fluid in another cycle with exhaust fluid of one cycle heating the fluid in another cycle
• F02C 6/04 - Gas-turbine plants providing heated or pressurised working fluid for other apparatus, e.g. without mechanical power output
• F02C 6/14 - Gas-turbine plants having means for storing energy, e.g. for meeting peak loads
• F02C 6/18 - Plural gas-turbine plantsCombinations of gas-turbine plants with other apparatusAdaptations of gas-turbine plants for special use using the waste heat of gas-turbine plants outside the plants themselves, e.g. gas-turbine power heat plants

Abstract

Aspects of the present disclosure include a jet impingement cooling system configured to cool high heat flux devices via a cooling fluid. The jet impingement cooling system may include a heatsink and a first supply surface. The heatsink is coupled to the high heat flux device or capable of being coupled to the high heat flux device. The heatsink includes a first impingement surface having exit orifices and impingement regions. The exit orifices are spaced-apart from each other and defined in the first impingement surface. The impingement regions are located between adjacent exit orifices. The first supply surface is spaced-apart from the first impingement surface and includes injection ports spaced-apart from each other and defined in the supply surface. The injection ports are oriented such that impingement jets therefrom are directed to impinge against the impingement regions.

IPC Classes  ?

• H05K 7/20 - Modifications to facilitate cooling, ventilating, or heating

Abstract

A topological spin memory effect, defined as the recovery of magnetic skyrmions or magnetic bubble skyrmions in magnetic thin films after a transition to a dramatically different spin texture, is used for encrypted non-volatile information storage. The storage strategy is based on magnetic skyrmions, that is, topologically protected spin textures comprising chiral domain walls surrounding small (e.g., nanometers to microns in diameter), typically circular, single-domain cores. Systems and methods are described for encrypted non-volatile information storage based on a spin memory effect in magnetic thin films that support skyrmions. Systems and methods encrypt and recover information stored in the form of magnetic skyrmions.

IPC Classes  ?

• H10N 50/10 - Magnetoresistive devices
• G11C 11/16 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using magnetic elements using elements in which the storage effect is based on magnetic spin effect
• H01F 10/32 - Spin-exchange-coupled multilayers, e.g. nanostructured superlattices
• H10B 61/00 - Magnetic memory devices, e.g. magnetoresistive RAM [MRAM] devices
• H10N 50/80 - Constructional details
• H10N 50/85 - Materials of the active region

Abstract

The present disclosure relates to a plant or plant part comprising increased expression of a polynucleotide encoding a CYP72A219 polypeptide that confers to the plant or plant part tolerance to HPPD inhibitor herbicides, such as tembotrione or mesotrione. The disclosure further provides kits for identifying herbicide resistant plants and methods for determining whether a plant is herbicide resistant.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae

Abstract

Embodiments described herein generally relate to processes for activation of C‒F bonds using an organic photoredox catalyst. Embodiments described herein also relate to processes for converting a substrate comprising a C‒F bond to a conversion product. In an embodiment, a process for converting an organofluoride is provided. The process includes forming a reaction mixture comprising an organofluoride, an organic catalyst, a co-catalyst, and a hydrogen source. The process further includes exposing the reaction mixture to light to convert the organofluoride to a conversion product. In another embodiment, a process for converting an organofluoride is provided. The process includes forming a reaction mixture comprising an organofluoride, an organic catalyst, a co-catalyst, and a coupling partner. The process further includes exposing the reaction mixture to light to convert the organofluoride to a conversion product.

IPC Classes  ?

• B01J 35/39 - Photocatalytic properties
• C07C 15/04 - Benzene
• C07C 5/00 - Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
• C07C 9/06 - Ethane

Abstract

Provided herein are methods for inactivating an influenza particle, the methods comprising contacting the influenza particle with UV light in the presence of riboflavin such that the integrity of the antigenic proteins of the influenza particle are preserved. Vaccine compositions comprising inactivated influenza particles, and methods of use thereof, are also provided

IPC Classes  ?

• C12N 7/06 - Inactivation or attenuationProducing viral sub-units by chemical treatment
• A61K 39/145 - Orthomyxoviridae, e.g. influenza virus
• A61P 31/16 - Antivirals for RNA viruses for influenza or rhinoviruses
• C07K 14/11 - Orthomyxoviridae, e.g. influenza virus

Abstract

The present disclosure relates to compositions and methods for targeting cytochrome P450 reductase that can be utilized to control weeds, invasive plants, or other undesired plants.

IPC Classes  ?

• C12N 15/52 - Genes encoding for enzymes or proenzymes
• A01N 27/00 - Biocides, pest repellants or attractants, or plant growth regulators containing hydrocarbons
• C12N 9/00 - Enzymes, e.g. ligases (6.)ProenzymesCompositions thereofProcesses for preparing, activating, inhibiting, separating, or purifying enzymes
• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells

Abstract

The disclosure relates to compositions and methods for reducing free asparagine concentration in the grain of wheat plants. The compositions comprise wheat plants, plant parts, plant cells, and seeds comprising a loss-of-function mutation in at least one endogenous ASPARAGINE SYNTHETASE 2 (ASN2) gene. The grain of wheat plants has reduced acrylamide-forming potential. Low acrylamide products produced from the grain are also provided.

IPC Classes  ?

• A01H 6/46 - Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize
• C12N 5/04 - Plant cells or tissues
• C12N 9/00 - Enzymes, e.g. ligases (6.)ProenzymesCompositions thereofProcesses for preparing, activating, inhibiting, separating, or purifying enzymes
• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae

Abstract

The present disclosure provides formulations and kits comprising cannabidivarinic acid (CBDVA) that can be used for protection of plants from pests, in particular cannabis plants. Methods of applying the formulations or kits to plants are also provided.

IPC Classes  ?

• A61K 36/185 - Magnoliopsida (dicotyledons)
• A01N 25/02 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
• A01N 65/00 - Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
• A01P 7/04 - Insecticides
• A61K 31/00 - Medicinal preparations containing organic active ingredients

Abstract

A method to produce ammonia in an electrochemical system, from a nitrogencontaining species, a proton source, a catalyst, and electricity, without the heat and pressure traditionally used in the industry to produce ammonia, wherein the catalyst comprises at least two transition metals.

IPC Classes  ?

• C25B 1/27 - Ammonia
• C25B 11/089 - Alloys
• C25B 15/02 - Process control or regulation
• C01C 1/02 - Preparation or separation of ammonia

Abstract

An adaptive seal includes an attachment configured to attach to a replacement heart valve to close gaps between the replacement heart valve and a patient's own and surrounding structure to reduce or to prevent paravalvular leakages.

IPC Classes  ?

• A61F 2/24 - Heart valves
• A61F 2/95 - Instruments specially adapted for placement or removal of stents or stent-grafts

Abstract

in vivo in vivoMycobacterium tuberculosis Mycobacterium tuberculosis (Mtb) when delivered within the nanoparticles is less than the amount of the same antimicrobial delivered alone.

IPC Classes  ?

• A61K 31/47 - QuinolinesIsoquinolines
• A61K 38/03 - Peptides having up to 20 amino acids in an undefined or only partially defined sequenceDerivatives thereof
• A61K 38/04 - Peptides having up to 20 amino acids in a fully defined sequenceDerivatives thereof
• A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
• A61P 31/04 - Antibacterial agents

Abstract

An ultra-efficient turbo-compression cooling system links an organic Rankine power cycle and a vapor compression cooling cycle using a turbine and compressor that shares a single shaft and further linked to an evaporative condenser. The power cycle implements a waste heat exchanger configured to evaporate a working fluid and a turbine configured to receive the evaporated working fluid. The turbine has a plurality of vanes disposed around a central shaft and configured to rotate as the working fluid expands to a lower pressure within the turbine. An evaporative condenser then condenses the working fluid to a saturated liquid and a mechanical pump pumps the saturated liquid to reenter the waste heat waste heat exchanger. The cooling cycle implements a compressor configured to increase the pressure of the working fluid, with the evaporative condenser (shared with the power cycle) configured to condense the working fluid to a saturated liquid upon exiting the compressor, an expansion valve wherein the working fluid expands to a lower pressure, and an evaporator rejecting heat from a circulating fluid to the working fluid, thereby cooling the circulating fluid.

IPC Classes  ?

• F01K 23/10 - Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids the engine cycles being thermally coupled combustion heat from one cycle heating the fluid in another cycle with exhaust fluid of one cycle heating the fluid in another cycle
• F01K 11/02 - Steam engine plants characterised by the engines being structurally combined with boilers or condensers the engines being turbines
• F01K 25/10 - Plants or engines characterised by use of special working fluids, not otherwise provided forPlants operating in closed cycles and not otherwise provided for using special vapours the vapours being cold, e.g. ammonia, carbon dioxide, ether

Abstract

A portable sampler, the sampler including a sampler assembly having a housing that includes a receiver defined therein for interchangeably receiving a number of removable inlet assemblies, the removable inlet assemblies including a respirable inlet assembly and a thoracic inlet assembly. The respirable inlet assembly includes a hybrid cyclone assembly, the hybrid cyclone assembly including an impaction stage and a cyclone in series. The thoracic inlet assembly includes an inlet slot configured to function as a size-selective inlet. Another thoracic inlet assembly includes a housing having a number of openings configured to receive a sample airflow; an inlet insert through which an inlet aperture is defined; a prequalification chamber defined between a lower surface of the housing and an upper surface of the inlet insert; and a protrusion extending downward from the lower surface of the housing into the inlet aperture of the inlet insert to from an inlet slot.

IPC Classes  ?

• A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
• G01N 1/22 - Devices for withdrawing samples in the gaseous state
• G01N 15/02 - Investigating particle size or size distribution

Abstract

Aspects of the present disclosure include a robotic wheel that includes a tensegrity structure, an inner hub, an outer hub, and a cable. The tensegrity structure includes multiple rigid rods and multiple elastic cables, and the tensegrity structure defines a longitudinal axis, a first end and a second end. The inner hub is disposed at the first end of the tensegrity structure and the outer hub is disposed at the second end of the tensegrity structure. The cable is in contact with the outer hub, extends through the tensegrity structure parallel to the longitudinal axis, and extends through the inner hub. The cable is operable to retract to transition the tensegrity structure to a collapsed state and to extend to transition the tensegrity structure an expanded state.

IPC Classes  ?

• B60B 19/04 - Wheels not otherwise provided for or having characteristics specified in one of the subgroups of this group expansible
• B25J 5/00 - Manipulators mounted on wheels or on carriages

Abstract

The disclosure relates to compositions and methods for reducing polyphenol oxidase (PPO) activity in plants, including wheat plants. The compositions comprise plants, plant parts, plant cells, and seeds comprising a mutation in at least one endogenous PPO1 or PPO2 gene. Products produced from the grain of plants have reduced browning.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C12N 9/22 - Ribonucleases
• C12N 15/11 - DNA or RNA fragmentsModified forms thereof

Abstract

Various implementations include a method for treating a bone defect of a first bone structure and a second bone structure of a patient. The method includes positioning a biodegradable scaffold within a passage of a biodegradable sleeve, wherein the passage extends from a first end to a second end of the biodegradable sleeve, wherein a geometry of the biodegradable sleeve induces strain on a portion of the biodegradable scaffold when a force is applied to the biodegradable sleeve; and positioning the biodegradable sleeve along the first bone structure and the second bone structure to span the bone defect.

IPC Classes  ?

• A61F 2/28 - Bones
• A61F 2/30 - Joints

Abstract

The present invention is directed to the field of light detection, in particular light detection in photochemical reactors, specifically photochemical reactors adapted for the inactivation of pathogens. A system and method for detecting light emitted into a photoreactor may include a housing containing a fluid channel configured to transfer a fluid containing a photosensitizer and a reactant from an inlet to an outlet preferably along a longitudinal axis, and at least one light source positioned adjacent to the fluid channel, again preferably along the longitudinal axis.

IPC Classes  ?

• A61L 2/08 - Radiation
• A61L 9/20 - Ultraviolet radiation
• G01J 1/42 - Photometry, e.g. photographic exposure meter using electric radiation detectors
• G01N 21/64 - FluorescencePhosphorescence

Abstract

The present disclosure provides methods, compositions, and systems related to the detection of cancer DNA. In particular, the present disclosure provides methods, compositions, and systems related to the electrochemical detection and/or quantification of cancer DNA in biological samples for monitoring of disease (e.g., cancer) status.

IPC Classes  ?

• C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
• C12Q 1/6809 - Methods for determination or identification of nucleic acids involving differential detection
• C12Q 1/6825 - Nucleic acid detection involving sensors
• G01N 33/48 - Biological material, e.g. blood, urineHaemocytometers

Abstract

A multiplexed capillary-flow immunoassay device configured for the simultaneous detection of multiple analytes, specifically, a testing assembly including a detection area, a fluid inlet, and a microfluidic network including at least two microfluidic pathways directed to distinct detection areas each configured to detect a different analyte.

IPC Classes  ?

• B81B 1/00 - Devices without movable or flexible elements, e.g. microcapillary devices
• G01N 21/73 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light thermally excited using plasma burners or torches
• G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
• G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
• G01N 35/08 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis

Abstract

A method may include receiving video data that includes frames representative of infrared radiation within a scene. Each of the frames may include pixels The method may also include identifying pixels within the frames that correspond to a gas plume released by a gas source within the scene based on the infrared radiation. In addition, the method may include determining a size of the gas plume within each frame based on the identified pixels.

IPC Classes  ?

• G06V 10/36 - Applying a local operator, i.e. means to operate on image points situated in the vicinity of a given pointNon-linear local filtering operations, e.g. median filtering
• G01M 3/04 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point
• G06V 10/30 - Noise filtering
• G06V 10/34 - Smoothing or thinning of the patternMorphological operationsSkeletonisation
• G06V 10/766 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using regression, e.g. by projecting features on hyperplanes
• G06V 20/40 - ScenesScene-specific elements in video content

Abstract

The true impact of preharvest factors such as crop load, canopy position, cultivar and rootstock on peach internal quality can be determined using multivariate visible light radiation (Vis) and near infrared spectroscopy (NIRS) prediction models to non-destructively assess peach internal quality (dry matter content, DMC; soluble solids concentration, SSC) and maturity (index of absorbance difference, IAD). A novel crop load×fruit developmental stage protocol allowed accurate multivariate Vis-NIRS-based prediction models development for three major yellow fleshed peach typologies (fully red over-colored, early-ripening bi-colored and late-ripening bi-colored) to non-destructively assess peach internal quality (DMC and SSC) and maturity (IAD) with a single scan during fruit growth and development in the field. The impact of preharvest factors such as crop load and canopy position on peach quality and maturity can be evaluated across a variety of peach cultivars using this novel technology.

IPC Classes  ?

• G01N 21/3563 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing solidsPreparation of samples therefor
• G01N 21/3581 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using far infrared lightInvestigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using Terahertz radiation

Abstract

Various implementations include a photovoltaic (PV) module. The PV module includes a PV cell and a transparent layer. The PV cell has a first side and second side opposite and spaced apart from the first side of the PV cell. The first side is configured to absorb light. The transparent layer has a first side and a second side opposite and spaced apart from the first side of the transparent layer. The second side of the transparent layer is adjacent to and spaced apart from the first side of the PV cell to define a gap.

IPC Classes  ?

• H01L 31/043 - Mechanically stacked PV cells
• H01L 31/042 - PV modules or arrays of single PV cells
• H01L 31/048 - Encapsulation of modules

Abstract

The present application relates to vanadium compounds. More specifically, the present application relates to pharmaceutical compositions comprising vanadium salts, use thereof and methods using the same. The present application also includes compositions comprising vanadium compounds and a therapeutic or prophylactic virus providing for increased virus infection, spread, titer, activity, cytotoxicity and/or immunotherapeutic activity.

IPC Classes  ?

• A61K 31/28 - Compounds containing heavy metals
• A61K 33/42 - PhosphorusCompounds thereof
• A61K 35/766 - Rhabdovirus, e.g. vesicular stomatitis virus
• A61K 35/768 - Oncolytic viruses not provided for in groups
• A61P 35/00 - Antineoplastic agents

Abstract

Various implementations include a method of printing and curing of thermoset resin. The method includes outputting a thermoset resin from an outlet of a feeder and directing a stimulus from a stimulation source toward a portion of the output thermoset resin that is downstream from the outlet of the feeder. The stimulus is configured to heat the portion of the output thermoset resin to fully cure the portion of the output thermoset resin.

IPC Classes  ?

• B29C 64/295 - Heating elements
• B29C 64/165 - Processes of additive manufacturing using a combination of solid and fluid materials, e.g. a powder selectively bound by a liquid binder, catalyst, inhibitor or energy absorber
• B29C 64/209 - HeadsNozzles
• B29C 64/218 - Rollers
• B29C 64/268 - Arrangements for irradiation using laser beamsArrangements for irradiation using electron beams [EB]
• B29K 63/00 - Use of epoxy resins as moulding material
• B29K 75/00 - Use of polyureas or polyurethanes as moulding material
• B29K 105/08 - Condition, form or state of moulded material containing reinforcements, fillers or inserts of continuous length, e.g. cords, rovings, mats, fabrics, strands or yarns
• B29K 105/12 - Condition, form or state of moulded material containing reinforcements, fillers or inserts of short lengths, e.g. chopped filaments, staple fibres or bristles
• B29K 105/16 - Fillers
• B33Y 30/00 - Apparatus for additive manufacturingDetails thereof or accessories therefor
• B33Y 70/10 - Composites of different types of material, e.g. mixtures of ceramics and polymers or mixtures of metals and biomaterials

Abstract

Embodiments of the present disclosure generally relate to multiblock copolymers and to uses thereof. Embodiments of the present disclosure also generally relate to processes for making multiblock copolymers, to processes for depolymerizing multiblock copolymers, and to processes for chemically recycling multiblock copolymers. In an embodiment, a process for forming a copolymer is provided. The process includes forming a first reaction mixture comprising a first difunctionalized compound having two first reactive chain end groups, and a second difunctionalized compound having two second reactive chain end groups. The process further includes introducing a catalyst, and an optional solvent with the first reaction mixture to form a second reaction mixture; and reacting the second reaction mixture to induce step-growth polymerization of the first difunctionalized compound and the second difunctionalized compound to form a copolymer comprising a reaction product or an adduct of the first and second difunctionalized compounds

IPC Classes  ?

• C08G 63/12 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
• B01J 23/34 - Manganese
• B01J 23/46 - Ruthenium, rhodium, osmium or iridium
• B01J 23/745 - Iron
• B01J 23/75 - Cobalt
• B01J 27/13 - Platinum group metals
• C08G 63/16 - Dicarboxylic acids and dihydroxy compounds

Abstract

The present disclosure relates to a composition that includes a first copolymer having a first repeat unit and a second repeat unit as defined by Structure (I) The present disclosure relates to a composition that includes a first copolymer having a first repeat unit and a second repeat unit as defined by Structure (I) The present disclosure relates to a composition that includes a first copolymer having a first repeat unit and a second repeat unit as defined by Structure (I) where is a covalent bond, U1 is a molar fraction of the first repeat unit, (1−U1) is a molar fraction of the second repeat unit, 0≤n≤20, 0≤m≤20, 0

IPC Classes  ?

• C08G 63/698 - Polyesters containing atoms other than carbon, hydrogen, and oxygen containing boron
• C08G 63/688 - Polyesters containing atoms other than carbon, hydrogen, and oxygen containing sulfur

Abstract

A method may include receiving video data that includes frames representative of infrared radiation within a scene. Each of the frames may include pixels The method may also include identifying pixels within the frames that correspond to a gas plume released by a gas source within the scene based on the infrared radiation. In addition, the method may include determining a size of the gas plume within each frame based on the identified pixels.

IPC Classes  ?

• G06V 10/36 - Applying a local operator, i.e. means to operate on image points situated in the vicinity of a given pointNon-linear local filtering operations, e.g. median filtering
• G01M 3/04 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point
• G06V 10/30 - Noise filtering
• G06V 10/34 - Smoothing or thinning of the patternMorphological operationsSkeletonisation
• G06V 10/766 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using regression, e.g. by projecting features on hyperplanes
• G06V 20/40 - ScenesScene-specific elements in video content

Abstract

Various implementations include a filament winding system. The system includes a mandrel, a motor, and an energy source. The mandrel has a rotational axis. The mandrel has an outer surface extending circumferentially around the rotational axis. The motor is for causing the mandrel to rotate about the rotation axis. The energy source is for directing energy toward a fiber wound around the outer surface of the mandrel.

IPC Classes  ?

• B29C 53/82 - Cores or mandrels
• B29C 53/62 - Winding and joining, e.g. winding spirally helically using internal forming surfaces, e.g. mandrels rotatable about the winding axis
• B29C 53/66 - Winding and joining, e.g. winding spirally helically using internal forming surfaces, e.g. mandrels rotatable about the winding axis with axially movable winding feed member
• B29C 53/80 - Component parts, details or accessoriesAuxiliary operations
• B29C 53/84 - Heating or cooling
• B29C 53/60 - Winding and joining, e.g. winding spirally helically using internal forming surfaces, e.g. mandrels
• B29B 15/14 - Coating or impregnating of reinforcements of indefinite length of filaments or wires

Abstract

Provided herein are methods for inactivating an attenuated pathogen, the methods comprising contacting the microbe with UV light in the presence of riboflavin such that the integrity of the antigenic proteins of the pathogen is preserved In some embodiments, the viral pathogen is a African Swine Fever Virus (ASFV). Vaccine compositions comprising attenuated pathogen, and methods of use thereof, are also provided.

IPC Classes  ?

• A61K 39/02 - Bacterial antigens
• A61K 39/04 - Mycobacterium, e.g. Mycobacterium tuberculosis
• A61K 39/12 - Viral antigens
• C12N 7/04 - Inactivation or attenuationProducing viral sub-units

Abstract

The present disclosure relates to fibers prepared using decellularized liver ECM. The disclosure further provides in vitro cultures of human hepatocytes on decellularized liver ECM fibers, and the use of the cultures in developing and screening drugs.

IPC Classes  ?

• C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues

Goods & Services

Downloadable printable educational materials in the field of early education for children with intellectual and developmental disabilities and delays; downloadable printable educational activity cards and informational cards in the field of executive function skills; downloadable handbook featuring educational information in the field of executive functions skills development for parents of children with intellectual and developmental disabilities and delays; downloadable mobile application featuring an early education curriculum for children with intellectual and developmental disabilities and delays; downloadable mobile application featuring a log for parents to track curriculum progress and share feedback with the developers; downloadable videos featuring virtual courses of instruction in the field of executive functions skills development for parents of children with intellectual and developmental diabilities and delays and distribution of course material in connection therewith; Educational kit sold as a unit comprising printed hard copy handbooks, printed educational activity cards, and printed information cards featuring a curriculum for early education for children with intellectual and developmental disabilities and delays; Educational services, namely providing online virtual courses of instruction in the field of executive function skills development for parents of children with an intellectual and developmental disabilities and delays and distribution of course material in connection therewith; coaching services in the field of executive function skills development for parents of children with intellectual and developmental disabilities and delays; providing a website featuring non-downloadable videos and non-downloadable electronic publications in the nature of activity and informational cards and guide books in the field of early education for children with intellectual and developmental disabilities and delays; providing a website featuring educational information in the field of executive function skills development and activities in the nature of interactive online training services in the the field of executive function skills development for parents of children with intellectual and developmental disabilities and delays;

Abstract

A method for fabricating a bone-regeneration scaffold may include providing a printing material including a biologically-derived bone powder, and fabricating, via a 3D printer, the bone-regeneration scaffold using the printing material.

IPC Classes  ?

• A61L 27/22 - Polypeptides or derivatives thereof
• A61L 27/36 - Materials for prostheses or for coating prostheses containing ingredients of undetermined constitution or reaction products thereof

Abstract

In some aspects, disclosed herein is a method of determining pregnancy and identifying open cows, comprising breeding a cow, obtaining a genital tract sample from the cow, detecting a level of an interferon tau (IFNT) polypeptide in the genital tract sample; identifying the cow as pregnant if the level of IFNT is higher than a reference control or as not pregnant if the level of IFNT is the same as or lower than the reference control, and performing additional breeding of the cow if the cow is determined to be not pregnant.

IPC Classes  ?

• A01K 29/00 - Other apparatus for animal husbandry
• A01K 67/02 - Breeding vertebrates
• A61D 17/00 - Devices for indicating trouble during labour of animals
• G01N 33/48 - Biological material, e.g. blood, urineHaemocytometers
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• A61D 19/00 - Instruments or methods for reproduction or fertilisation

Abstract

Syndio-rich P3HB (sr-P3HB), readily synthesized from the eight-membered meso-dimethyl diolide, has a unique set of stereomicrostructures comprising enriched syndiotactic [rr] and no isotactic [mm] triads but abundant stereo-defects randomly distributed along the chain. This sr-P3HB material is characterized by high toughness (UT=96 MJ/m3), as a result of its high elongation at break (>400%) and tensile strength (34 MPa), crystallinity (Tm=114° C.), and optical clarity (due to its sub-micron spherulites), and good barrier properties, while it still biodegrades in freshwater and soil. On the other hand, iso-rich P3HB (ir-P3HB) can be synthesized from the eight-membered rac-dimethyl diolide. While sr-P3HB exhibits excellent adhesion strength toward a variety of substrates, both sr-P3HB and ir-P3HB can substantially toughen brittle stereoperfect biological or synthetic P3HB. Both sr-P3HB and ir-P3HB can also be obtained from the four-membered rac-beta-butyrolactone with appropriate catalysts.

IPC Classes  ?

• C08G 63/06 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxy carboxylic acids
• C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones
• C09J 167/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones

Abstract

Disclosed herein is a multilayer coating system present on a substrate and including at least two coating layers L1 and L2 different from one another, namely a first coating layer L1 applied over at least a portion of the substrate, and a second topcoat layer L2 applied over the first coating layer L1, where the topcoat layer L2 is formed from a coating composition including at least one block copolymer containing a backbone and at least two blocks B1 and B2 and side chains S1 and S2 including different polymeric moieties M1 and M2. Also disclosed herein are a method of preparing said multilayer coating system, a coated substrate obtainable therefrom, and a method of using a coating composition including the block copolymer for improving, in particular for increasing, the chromaticity of the multilayer coating system.

IPC Classes  ?

• C09D 187/00 - Coating compositions based on unspecified macromolecular compounds, obtained otherwise than by polymerisation reactions only involving unsaturated carbon-to-carbon bonds
• C08G 81/02 - Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers at least one of the polymers being obtained by reactions involving only carbon-to-carbon unsaturated bonds

Abstract

Disclosed herein is a multilayer coating system present on a substrate and including at least three coating layers L1, L2 and L3 different from one another, namely a first pigmented coating layer L1 applied over at least a portion of the substrate, a second coating layer L2 applied over the first pigmented coating layer L1, and a third coating layer L3 applied over the second coating layer L2, where the second coating layer L2 is formed from a coating composition including at least one block copolymer containing a backbone and at least two blocks B1 and B2 and side chains S1 and S2 including different polymeric moieties M1 and M2. Also disclosed herein are a method of preparing said multilayer coating system, a coated substrate obtainable therefrom, and a method of using a coating composition including the block copolymer for improving the chromaticity of the multilayer coating system.

IPC Classes  ?

• C09D 165/00 - Coating compositions based on macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chainCoating compositions based on derivatives of such polymers
• C08G 61/08 - Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes only aliphatic carbon atoms prepared by ring-opening of carbocyclic compounds of carbocyclic compounds containing one or more carbon-to-carbon double bonds in the ring
• C08G 63/08 - Lactones or lactides
• C09D 5/32 - Radiation-absorbing paints
• C09D 5/33 - Radiation-reflecting paints

Abstract

The present disclosure provides compositions and methods related to the treatment of non-tuberculous mycobacterial infections in a subject. In particular, the present disclosure provides compositions comprising an anti-malarial agent and associated methods of treating and/or preventing a non-tuberculous mycobacterial infection in a subject using the composition.

IPC Classes  ?

• A61K 31/357 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
• A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
• A61P 31/08 - Antibacterial agents for leprosy

Abstract

There is provided with a method for treating cancer, comprising administering a pharmaceutical composition to a patient with cancer in combination with an anti-cancer agent, the pharmaceutical composition. A compound is represented by General Formula (I) or a pharmaceutically acceptable salt thereof: There is provided with a method for treating cancer, comprising administering a pharmaceutical composition to a patient with cancer in combination with an anti-cancer agent, the pharmaceutical composition. A compound is represented by General Formula (I) or a pharmaceutically acceptable salt thereof: where R1 is an acyl residue from a fatty acid.

IPC Classes  ?

• A61K 31/7028 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
• A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
• A61P 35/00 - Antineoplastic agents

Abstract

A titanium superhydrophobic surface comprising a coating of a perfluorosilane on contiguous titania micrograins surrounded by crevices, the micrograins comprising a topography of nanopits shaped by contiguous peaks and valleys. The superhydrophobic surface has significantly increased hemocompatibility and enhanced antibacterial properties compared to an unmodified titanium surface. The increased hemocompatibility was confirmed by reduced platelet adhesion, reduced leukocyte adhesion, and reduced thrombus formation. The surface is prepared by a facile hydrothermal treatment of a titanium surface with sulfuric acid, leading to the formation of a unique micro-nano surface topography. The superhydrophobic surface was then achieved by coating the micro-nano titanium surface with a low energy silane using physical vapor deposition.

IPC Classes  ?

• A61L 27/30 - Inorganic materials
• A61L 27/50 - Materials characterised by their function or physical properties
• A61L 31/08 - Materials for coatings
• A61L 31/10 - Macromolecular materials
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites

Abstract

Disclosed herein are methods of carbon sequestration using microorganisms, such as soil microorganisms, capable of synthesizing or consuming degradation-resistant L-carbohydrates. In particular, methods of identifying and using microorganisms capable of synthesizing L-carbohydrates are provided, wherein microorganisms that synthesize L-carbohydrates are contacted with a soil source to sequester carbon. Also provided are methods of identifying and incorporating biomolecules such as genes, peptides, and enzymes relevant for L-carbohydrate anabolism or catabolism into plants so the plants synthesize L-carbohydrates or do not consume L-carbohydrates, thereby sequestering carbon.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells

Abstract

The present disclosure provides a porous elastomer, methods of preparing the porous elastomer, and methods of using the porous elastomers. The porous elastomers described herewith may be hydrophilic and hydrophobic porous elastomers derived from a TPPE precursor composite.

IPC Classes  ?

• C09D 153/00 - Coating compositions based on block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bondsCoating compositions based on derivatives of such polymers
• B01D 71/80 - Block polymers
• H01M 50/40 - SeparatorsMembranesDiaphragmsSpacing elements inside cells
• H01M 50/403 - Manufacturing processes of separators, membranes or diaphragms

Abstract

The present disclosure provides compositions and methods for generating plants that can grow in saline conditions, or remove a salt or other impurity from water, for example plants that can remove sodium chloride from salt or sea water, and plants that can produce purified water from salt or sea water.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C02F 3/32 - Biological treatment of water, waste water, or sewage characterised by the animals or plants used, e.g. algae
• C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants

Abstract

Disclosed are various synthetic methods to prepare structural analogs of largazole and derivatives thereof. One structural analog is an amide isostere of largazole. Another structural analog replaces the thiazole ring of largazole with a pyridine moiety or an oxazole moiety. Also disclosed are various intermediate compounds obtained when preparing structural analogs of largazole and derivatives thereof, including macrocycle analogs having an alcohol functionality.

IPC Classes  ?

• C07D 513/18 - Bridged systems

Abstract

The present disclosure provides methods, kits, and compositions comprising β-alethine and one or more immune modulators and methods to determine when they are advantageous. Particular applications include the use of β-alethine and one or more immune modulators in the treatment of cancer.

IPC Classes  ?

• A61K 31/16 - Amides, e.g. hydroxamic acids
• A61P 35/00 - Antineoplastic agents
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61K 38/20 - Interleukins
• A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
• C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

Abstract

This disclosure describes systems, methods, and apparatus for a distributed controller. The distributed controller can include a traditional closed or open loop feedback controller followed by an empirically derived mapping that converts the controller output to a modified output, where the controller optimizes stability and the empirically derived mapping optimizes performance. The empirically derived mapping can be formed of coefficients representing linear controllers at inflection points, where the linear controllers are inversely related to a system model. The system model can comprise a static linear model, a dynamic linear model, and a total uncertainty. The static linear model can be derived from large signal steady state analysis, the dynamic nonlinear model can be derived from small signal transient analysis, and the uncertainty can be derived from small signal steady state analysis.

IPC Classes  ?

• G05B 19/4155 - Numerical control [NC], i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form characterised by programme execution, i.e. part programme or machine function execution, e.g. selection of a programme

Abstract

Embodiments of the present invention generally relate to compositions and methods for treating acute or chronic bacterial infections of joints, tendons, ligaments, implants and associated soft tissues. In other embodiments, compositions of use herein generally relate to activated MSCs or iMSCs combined with antibiotics having reduced cytotoxicity for the treatment of bacterial infections of joints, tendons, ligaments, implants and associated soft tissue structures.

IPC Classes  ?

• A61K 35/28 - Bone marrowHaematopoietic stem cellsMesenchymal stem cells of any origin, e.g. adipose-derived stem cells
• A61K 38/14 - Peptides containing saccharide radicalsDerivatives thereof
• A61K 31/43 - Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula , e.g. penicillins, penems
• A61K 31/7056 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
• A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
• A61K 31/546 - Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula , e.g. cephalosporins, cefaclor, cephalexine containing further heterocyclic rings, e.g. cephalothin
• A61P 31/04 - Antibacterial agents

Abstract

A new set of bench-stable fluoroalkylphosphines that directly convert C—H bonds in pyridine building blocks, drug-like fragments, and pharmaceuticals, into fluoroalkyl derivatives. No pre-installed functional groups or directing motifs are required. The reaction tolerates a variety of sterically and electronically distinct pyridines and is exclusively selective for the 4-position in most cases. The reaction proceeds via initial phosphonium salt formation followed by sp2-sp3 phosphorus ligand-coupling, an underdeveloped manifold for C—C bond formation.

IPC Classes  ?

• C07F 9/572 - Five-membered rings
• C07B 47/00 - Formation or introduction of functional groups not provided for in groups
• C07F 9/50 - Organo-phosphines

Abstract

The present disclosure provides compositions and methods for sensing a target substance of interest in the environment and inducing gene expression in response thereto, useful for detection of biological and chemical agents and environmental pollutants.

IPC Classes  ?

• C07K 14/705 - ReceptorsCell surface antigensCell surface determinants
• C12N 15/62 - DNA sequences coding for fusion proteins
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)

Abstract

In accordance with the purposes of the disclosed materials and methods, as embodied and broadly described herein, the disclosed subject matter, in one aspect, relates to a thermoformed polymeric valved conduits for heart valve and methods of using and making thereof. The thermoformed polymeric valved conduits is formed via a thermoforming process that conforms the conduit to a mold; the process forms a conduit that is flexible, resizablke, and/or deformable after being formed.

IPC Classes  ?

• A61F 2/24 - Heart valves
• A61F 2/06 - Blood vessels
• A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
• A61F 2/958 - Inflatable balloons for placing stents or stent-grafts
• B29C 51/26 - Component parts, details or accessoriesAuxiliary operations

Abstract

The present disclosure relates to data storage systems and methods of making thereof. Aspects of the disclosure further relate to engineered porous protein crystals that bind and adsorb guest information storage mediums such as DNA.

IPC Classes  ?

• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• C12Q 1/686 - Polymerase chain reaction [PCR]

Abstract

A power plant system is disclosed. The power plant system includes a combustor configured, a turbine configured to generate electricity, a heat exchanger and a steam turbine, a carbon capture system configured to remove at least a portion of carbon-based gasses from the flue gas downstream from the heat recovery steam generator, and a thermal storage system including a hot storage unit configured to store thermal energy at a hot temperature, the hot temperature greater than ambient temperature. The power plant is configured to operate in at least a first mode for storing thermal energy in the thermal storage system and a second mode for releasing the stored thermal energy from the thermal storage system and during the second mode, heat stored in the hot storage unit is transferred to the carbon capture system.

IPC Classes  ?

• F01K 23/10 - Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids the engine cycles being thermally coupled combustion heat from one cycle heating the fluid in another cycle with exhaust fluid of one cycle heating the fluid in another cycle
• F01K 15/00 - Adaptations of steam engine plants for special use

Abstract

S. cerevisiae, suggesting a strategy to improve the yield of ethanol and other yeast fermentation products by manipulating native biological control systems.

IPC Classes  ?

• C12P 7/22 - Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
• C12N 1/18 - Baker's yeastBrewer's yeast
• C12P 7/06 - Ethanol, i.e. non-beverage
• C12R 1/865 - Saccharomyces cerevisiae

Abstract

A device for emitting photons into a fluid is disclosed. The device includes a fluid channel configured to transfer the fluid from an inlet to an outlet thereof and the fluid channel having a helical pathway wound about a longitudinal axis. The device also includes at least one inner light source adjacent the fluid channel, the at least one inner light source positioned between the fluid channel and the longitudinal axis and at least one outer light source adjacent the fluid channel, the fluid channel positioned between the outer light source and the longitudinal axis.

IPC Classes  ?

• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61L 2/10 - Ultraviolet radiation

Abstract

A biocompatible implant, as well as method of fabricating the implant and repairing an annular defect in annulus fibrosus (AF) of an intervertebral disc (IVD) disposed in a functional spinal unit (FSU), includes an insert that provides faces that can interface with the defect to repair or treat the AF. The implant can deliver biological and mechanical factors to enhance healing in an annular defect and prevent recurrence of herniation symptoms. The implant can be fabricated using a hybrid of first fibrous scaffold structure including at least a first layer and a second layer of first fibers fabricated via three-dimensional fiber deposition (3FD) and second fibrous scaffold structure including a third layer and a fourth layer of second fibers formed via melt electrowriting (MEW). Suitable attachment methods, including bio-adhesives can be used to bond the implant to the IVD and/or FSU.

IPC Classes  ?

• A61F 2/44 - Joints for the spine, e.g. vertebrae, spinal discs
• A61F 2/30 - Joints

IPC Classes  ?

• C08G 63/02 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds
• C08G 63/06 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxy carboxylic acids
• C08G 63/08 - Lactones or lactides
• C08G 63/668 - Polyesters containing oxygen in the form of ether groups derived from polycarboxylic acids and polyhydroxy compounds
• C08G 69/14 - Lactams
• C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones

Abstract

Provided herein are methods for inactivating a microbe, the methods comprising contacting the microbe with UV light in the presence of riboflavin. In some embodiments, the microbe is a Mycobacterium tuberculosis. Vaccine compositions comprising inactivated microbes, and methods of use thereof, are also provided.

IPC Classes  ?

• A61K 39/04 - Mycobacterium, e.g. Mycobacterium tuberculosis
• A61K 41/17 - Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
• A61P 31/06 - Antibacterial agents for tuberculosis
• A61K 35/74 - Bacteria

Abstract

aaaa-disubstitution in PHAs enhances the thermal stability so substantially that the PHAs become melt-processable. Synergistically, this structural modification also endows the PHAs with the mechanical toughness, intrinsic crystallinity, and closed-loop chemical recyclability.

IPC Classes  ?

• C08G 63/08 - Lactones or lactides
• C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones
• C08G 63/02 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds
• C08G 63/06 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxy carboxylic acids
• C08G 63/668 - Polyesters containing oxygen in the form of ether groups derived from polycarboxylic acids and polyhydroxy compounds
• C08G 69/14 - Lactams

Abstract

Embodiments of the present disclosure relate to a denticle array. The denticle array includes a substrate and a plurality of denticles coupled to the substrate. Each denticle of the plurality of denticles includes an upper portion and a lower portion. The upper portion includes an upper body. The lower portion includes a lower body. The upper body includes a first prong extending from a front end of the denticle to a rear end of the denticle, a second prong extending from the front end of the denticle to a rear end of the denticle, and a third prong extending from the front end of the denticle to a rear end of the denticle. A first ridge separates the first prong and second prong. A second ridge separates the first prong from the third prong. The first prong has a length greater than the second prong and the third prong.

IPC Classes  ?

• D01F 6/64 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from homopolycondensation products from polyesters from polycarbonates
• D01F 6/18 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from homopolymers obtained by reactions only involving carbon-to-carbon unsaturated bonds from polymers of unsaturated nitriles, e.g. polyacrylonitrile, polyvinylidene cyanide
• D01F 6/70 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from homopolycondensation products from polyurethanes
• D01F 11/12 - Chemical after-treatment of man-made filaments or the like during manufacture of carbon with inorganic substances

Abstract

Provided herein are methods for inactivating a viral particle, the methods comprising contacting the viral particle with UV light in the presence of riboflavin. In some embodiments, the viral particle is a SARS-CoV-2 particle. Vaccine compositions comprising inactivated viral particles (e.g., inactivated SARS-CoV-2 particles) are also provided. In some embodiments, the vaccine compositions comprise an adjuvant capable of promoting a Th1-type immune response.

IPC Classes  ?

• A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
• A61P 31/14 - Antivirals for RNA viruses
• A61K 39/215 - Coronaviridae, e.g. avian infectious bronchitis virus

Abstract

in situin situ generated dynamic thermosets exhibit intrinsic reprocessability as well as enhanced tensile strength and creep resistance, relative to virgin plastics. This approach avoids the need for de/reconstruction and thus provides the maximum recovery of the endowed energy and materials value of the individual plastics.

IPC Classes  ?

• C07D 403/02 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings
• C07D 403/10 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing aromatic rings
• C08K 5/3442 - Heterocyclic compounds having nitrogen in the ring having two nitrogen atoms in the ring
• C07D 229/02 - Heterocyclic compounds containing rings of less than five members having two nitrogen atoms as the only ring hetero atoms containing three-membered rings

Abstract

The present disclosure provides thermoplastic elastomer (TPE) composites, TPE hydrogel composites, TPE gel polymer electrolyte (GPE) composites, methods of preparing the TPE composites, methods of preparing the TPE hydrogel composites, methods of preparing the TPE GPE composites. The thermoplastic elastomer (TPE) composite comprises a first styrenic thermoplastic elastomer and a second styrenic thermoplastic elastomer, wherein the first and second styrenic thermoplastic elastomers each independently comprise at least one non-hydrogenated or hydrogenated styrene block.

IPC Classes  ?

• H01M 10/0565 - Polymeric materials, e.g. gel-type or solid-type
• H01M 10/056 - Accumulators with non-aqueous electrolyte characterised by the materials used as electrolytes, e.g. mixed inorganic/organic electrolytes
• H01M 10/0564 - Accumulators with non-aqueous electrolyte characterised by the materials used as electrolytes, e.g. mixed inorganic/organic electrolytes the electrolyte being constituted of organic materials only

Abstract

The present disclosure provides compositions and methods for sensing a target substance of interest in the environment and inducing gene expression in response thereto, useful for detection of biological and chemical agents and environmental pollutants.

IPC Classes  ?

• C07K 14/705 - ReceptorsCell surface antigensCell surface determinants
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12N 15/62 - DNA sequences coding for fusion proteins

Abstract

A microfluidic device includes a device body defining a microfluidic pathway including a first channel, a second channel downstream of the first channel, and a junction including a transition between the first channel and the second channel. The transition is configured to inhibit fluid entering the transition from the first channel from forming a meniscus across the second channel, thereby inhibiting capillary-driven flow into the second channel. The microfluidic device further includes a valve that, when activated while capillary-driven flow of the fluid is inhibited at the transition, induces capillary-driven flow through the second channel by facilitating formation of the meniscus.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers

Abstract

A system for generating steam for industrial heat. The system may include a plurality of heat pump cycles in thermal communication with each other and in thermal communication with a steam generation cycle. The plurality of heat pump cycles may include first and second heat pump cycles. The first heat pump circulates a first a working fluid and includes a first heat exchanger. The second heat pump cycle circulates a second working fluid and includes a second heat exchanger. The first heat exchanger transfers heat from the first to the second working fluid. The second heat exchanger transfers heat to a third working fluid in the steam generation cycle.

IPC Classes  ?

• F22B 1/16 - Methods of steam generation characterised by form of heating method by exploitation of the heat content of hot heat carriers the heat carrier being hot liquid or hot vapour, e.g. waste liquid, waste vapour
• F01K 9/00 - Steam engine plants characterised by condensers arranged or modified to co-operate with the engines
• F01K 19/04 - Regenerating by compression in combination with cooling or heating

Abstract

An assay device includes a colorimetric testing assembly including a detection area, a fluid inlet, and a microfluidic network including a first path extending to the detection area and a second path extending to the detection area. When a fluid (e.g., a buffer fluid or a combined buffer and sample solution) is provided to the fluid inlet, a first portion of the fluid rehydrates a first dried reagent (e.g., a dried enzyme label) disposed along the first path to produce a first rehydrated reagent and a second portion of the fluid rehydrates a second dried reagent (e.g., a dried substrate) to produce a second rehydrated reagent. The first rehydrated reagent and the second rehydrated reagent are then sequentially delivered to the detection area by capillary-driven flow to perform the assay.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals

Abstract

An assay device includes an electrochemical testing assembly having a test channel including a capture reagent selected to capture a target analyte and an electrode having a surface in communication with the test channel. The assay device further includes a microfluidic network in communication with the test channel, a buffer fluid inlet in communication with the microfluidic network, and a detection reagent disposed within the microfluidic network. When a buffer fluid is provided to the buffer fluid inlet, the buffer fluid transports the detection reagent to the test channel by capillary-driven flow, and wherein the electrode is configured to measure an electrical response indicating capture of the target analyte by the capture reagent after transportation of the detection reagent to the test channel.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers

Abstract

An exemplary system and method are disclosed for a digital microfluidic chip cartridge and system configured for electro-wetting on dielectric (EWOD) microfluidic operations and experimental analysis. The exemplary portable lab-on-a-chip devices and systems can be configured to execute complex assays such as DNA isolation employing integrated sensor and electronics can analyze results. The EWOD or digital microfluidic cartridge can be configured with customizable assays having preloaded reagents targeted specifically for a given assay that can be used in an analysis in the field (i.e., point of care, i.e., not in a central laboratory) using a disposable or recyclable assay cartridge system. The cartridge and portable instrument can operate on specific instructions based on the algorithm intended for the assay.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers

Abstract

Aspects of the present disclosure include a jet impingement cooling system configured to cool high heat flux devices via a cooling fluid. The jet impingement cooling system may include a heatsink and a first supply surface. The heatsink is coupled to the high heat flux device or capable of being coupled to the high heat flux device. The heatsink includes a first impingement surface having exit orifices and impingement regions. The exit orifices are spaced-apart from each other and defined in the first impingement surface. The impingement regions are located between adjacent exit orifices. The first supply surface is spaced-apart from the first impingement surface and includes injection ports spaced-apart from each other and defined in the supply surface. The injection ports are oriented such that impingement jets therefrom are directed to impinge against the impingement regions.

IPC Classes  ?

• H01L 23/473 - Arrangements for cooling, heating, ventilating or temperature compensation involving the transfer of heat by flowing fluids by flowing liquids
• F28F 3/12 - Elements constructed in the shape of a hollow panel, e.g. with channels
• H01L 23/367 - Cooling facilitated by shape of device
• H01L 23/467 - Arrangements for cooling, heating, ventilating or temperature compensation involving the transfer of heat by flowing fluids by flowing gases, e.g. air
• F28D 15/02 - Heat-exchange apparatus with the intermediate heat-transfer medium in closed tubes passing into or through the conduit walls in which the medium condenses and evaporates, e.g. heat-pipes
• F28F 13/06 - Arrangements for modifying heat transfer, e.g. increasing, decreasing by affecting the pattern of flow of the heat-exchange media
• F28F 27/02 - Control arrangements or safety devices specially adapted for heat-exchange or heat-transfer apparatus for controlling the distribution of heat-exchange media between different channels
• H05K 7/20 - Modifications to facilitate cooling, ventilating, or heating

IPC Classes  ?

• A01H 3/04 - Processes for modifying phenotypes by treatment with chemicals
• C12N 15/09 - Recombinant DNA-technology
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells

Abstract

The disclosure relates to 2'‐deoxy‐2'‐fluoroarabinonucleic acid (FANA) antisense oligonucleotides that can be utilized to control weeds, invasive plants, or other undesired plants.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• A01H 3/04 - Processes for modifying phenotypes by treatment with chemicals
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A01N 61/00 - Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
• A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
• C12N 15/09 - Recombinant DNA-technology

Abstract

A tuber seed cutter sterilization device is disclosed. The tuber seed cutter is configured to receive a flammable gas and sterilize a tuber seed cutter having a rotational blade and a tuber conveyer, the rotational blade is configured to rotate about a longitudinal axis of a rotational shaft. The tuber seed cutter includes a fluid channel configured to receive the flammable gas at an inlet port and direct the flammable gas to a pair of outlet ports, each outlet port of the pair of outlet ports positioned at opposite axial sides of the rotational blade. The flammable gas is configured to be ignited into a flame at each outlet port of the pair of outlet ports and each flame of the pair of outlet ports is configured to heat opposite outer surfaces of the rotational blade.

IPC Classes  ?

• A01C 1/00 - Apparatus, or methods of use thereof, for testing or treating seed, roots, or the like, prior to sowing or planting
• A01C 1/08 - Immunising seed
• A23L 19/10 - Products from fruits or vegetablesPreparation or treatment thereof of tuberous or like starch containing root crops
• A23L 19/12 - Products from fruits or vegetablesPreparation or treatment thereof of tuberous or like starch containing root crops of potatoes
• A23L 3/00 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61L 2/04 - Heat

Abstract

Embodiments of the present disclosure relate to methods of a method of making agricultural waste ash supplementary cementitious materials (AWASCMs), the method includes pretreating agricultural waste with acid, burning the acid pretreated agricultural waste to form agricultural waste ash (AWA), heat treating the AWA, grinding the AWA into an AWA supplemental cementitious material (AWASCM), and mixing the AWASCM with cement, water, and supplementary cementitious materials (SCMs) to create a cement paste. Embodiments of the present disclosure relate to a composition including sand, coarse aggregate, and cementitious materials. The cementitious materials includes cement, a SCM, and an AWASCM. The AWASCM includes an AWA and AWF.

IPC Classes  ?

• C04B 28/02 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing hydraulic cements other than calcium sulfates
• C04B 18/24 - Vegetable refuse, e.g. rice husks, maize-ear refuseCellulosic materials, e.g. paper
• C04B 7/28 - Cements from oil shales, residues or waste other than slag from combustion residues

Abstract

An upflow leach bed reactor configured to contain a substrate is provided. The reactor includes a container comprising a floor and a sidewall and configured to contain the substrate. The reactor further includes a fluid injection system including a plurality of fluid inlet ports arranged in an array across the floor. The fluid inlet ports can be moved between a first position below the substrate and a second position at least partially within the substrate. The reactor can also include a vertical drain extending from the top to the floor, between the substrate and the sidewall, and configured to permit downward liquid flow and inhibit upward liquid flow therethrough. The reactor can further include an inflatable bladder positioned adjacent the top of the container and configured to press downward against a top surface of the substrate.

IPC Classes  ?

• C02F 3/28 - Anaerobic digestion processes
• C02F 11/04 - Anaerobic treatmentProduction of methane by such processes
• C02F 3/30 - Aerobic and anaerobic processes

Abstract

The present disclosure provides materials and methods related to engineered bacteria for use in vaccines. In particular, the present disclosure provides novel compositions and methods for generating vaccine compositions comprising bacteria (e.g., Lactobacillus) engineered to express immunogenic polypeptides and immunogenicity-enhancing adjuvant polypeptides to treat and/or prevent infection from a pathogenic organism (e.g., coronavirus).

IPC Classes  ?

• A61K 35/744 - Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
• C12N 1/20 - BacteriaCulture media therefor
• C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
• C07K 14/165 - Coronaviridae, e.g. avian infectious bronchitis virus
• A61P 31/14 - Antivirals for RNA viruses
• C07K 14/14 - Reoviridae, e.g. rotavirus, bluetongue virus, Colorado tick fever virus

Abstract

A soil fractionation system can include a plurality of sample racks propelled by a drive system. Each sample rack can include a sample tube for holding a soil sample and a filter cup for receiving an extracted fraction of the soil sample. An extractor module of the fractionation system can include an extractor assembly and a filter assembly. A control system can control the relative positioning of the plurality of sample racks via the drive system, the relative movement between the extractor assembly and the sample tube, and the relative movement between the filter assembly and the filter cup.

IPC Classes  ?

• G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
• G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor

Abstract

Disclosed herein are systems and methods to perform hybridized transmission switching of an electric power system to avoid exceeding line ratings and minimize load shedding.

IPC Classes  ?

• H02J 3/00 - Circuit arrangements for ac mains or ac distribution networks
• H02J 3/14 - Circuit arrangements for ac mains or ac distribution networks for adjusting voltage in ac networks by changing a characteristic of the network load by switching loads on to, or off from, network, e.g. progressively balanced loading

Abstract

The present disclosure provides potentiometric ion selective electrodes, methods for preparing the potentiometric ion selective electrode, a microfluidic electrode array comprising the potentiometric ion selective electrodes, and methods of using the microfluidic electrode array to measure inorganic cations and inorganic anions in a solution.

IPC Classes  ?

• G01N 27/333 - Ion-selective electrodes or membranes
• G01N 27/416 - Systems

Abstract

A substrate having an antibacterial surface includes a chitosan matrix and water-stable metal-organic frameworks dispersed throughout the chitosan matrix. The water-stable metal-organic frameworks are present in an amount of 5% wt/wt to 20% wt/wt based on total solids of the substrate.

IPC Classes  ?

• A01N 25/10 - Macromolecular compounds
• A01N 55/02 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
• A61L 2/18 - Liquid substances
• A61L 2/23 - Solid substances, e.g. granules, powders, blocks, tablets
• C08B 37/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof
• C08K 5/56 - Organo-metallic compounds, i.e. organic compounds containing a metal-to-carbon bond
• A61L 101/34 - Hydroxy compounds
• A61L 101/42 - Organo-metallic compounds or complexes

Abstract

The present disclosure relates to a plant or plant part comprising increased expression of a polynucleotide encoding a CYP72A219 polypeptide that confers to the plant or plant part tolerance to HPPD inhibitor herbicides, such as tembotrione or mesotrione. The disclosure further provides kits for identifying herbicide resistant plants and methods for determining whether a plant is herbicide resistant.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants
• C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae

Abstract

In some embodiments, an apparatus includes a volatile memory, a non-volatile memory, a first processor coupled to the non-volatile memory and configured to receive a data set associated with an object and user information associated with a spatial position of a user in a multi-user virtual (IMVR) environment, and a second processor coupled to the volatile memory, the second processor configured to render an instance of the portion of the object in the IMVR environment from a perspective of the user based on the spatial position of the user. The first processor is configured to generate a look-up table (LUT) based on a set of inputs received from a user. The second processor is configured to render, based on the LUT and information related to a manipulation by a user, an updated instance of the portion of the object that manifests an effect of the manipulation in the IMVR environment.

IPC Classes  ?

• G06T 19/00 - Manipulating 3D models or images for computer graphics
• G02B 27/01 - Head-up displays
• G06T 1/60 - Memory management
• G06T 7/00 - Image analysis
• G06T 15/08 - Volume rendering
• G06T 19/20 - Editing of 3D images, e.g. changing shapes or colours, aligning objects or positioning parts

Abstract

Various implementations include a biomass dehydration system including a wet biomass chamber containing wet biomass, a belt or chain defining one or more cavities, two or more pulleys including a drive pulley that the belt or chain extend around and that are configured such that the cavities are disposable within the wet biomass chamber as the belt or chain moves along the pulleys to cause wet biomass to enter the cavities, and a drying chamber for dehydrating wet biomass disposed in the cavities into solid pellets. The drive pulley engages the belt or chain and causes the belt or chain to move around the pulleys. At least a portion of the belt or chain extends from the wet biomass chamber through the drying chamber. One of the pulleys includes one or more ejection protrusions for engaging the cavities and ejecting solid pellets from the cavities.

IPC Classes  ?

• F26B 3/04 - Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour circulating over, or surrounding, the materials or objects to be dried
• F26B 17/02 - Machines or apparatus for drying materials in loose, plastic, or fluidised form, e.g. granules, staple fibres, with progressive movement with movement performed by belts carrying the materialsMachines or apparatus for drying materials in loose, plastic, or fluidised form, e.g. granules, staple fibres, with progressive movement with movement performed by belts propelling the materials over stationary surfaces
• F26B 25/00 - Details of general application not covered by group or
• F26B 25/04 - Agitating, stirring, or scraping devices
• F26B 23/02 - Heating arrangements using combustion heating

Abstract

Embodiments of the present invention generally relate to novel immunostimulatory compositions of use to stimulate non-specific immune responses in a subject. In certain embodiments, immunostimulatory compositions disclosed herein can be directed to preventing or treating an infection, cancer or other immunocompromising health condition in the subject. In some embodiments, the immunostimulatory compositions disclosed herein enhance non-specific immune responses systemically or locally in the subject to treat or reduce the risk of onset of a health condition. In some embodiments, immunostimulatory compositions disclosed can be used to induce a non-specific immune response within mucosal surfaces such as the nasopharynx, upper respiratory tract, eye, GI tract, and reproductive tract to induce a non-specific immune response in order to reduce onset of or treat an infection or other health condition.

IPC Classes  ?

• A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
• A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
• A61K 47/38 - CelluloseDerivatives thereof
• A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids
• A61K 47/28 - Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 31/12 - Antivirals
• A61P 37/04 - Immunostimulants

Abstract

The present disclosure provides recombinant polynucleotide comprising a heterologous regulatory element operably linked to a first nucleic acid sequence encoding a cyanobacterial bicarbonate transporter protein. The disclosure also provides expression vectors comprising the recombinant polynucleotides as well as eukaryotic algae and methods of utilizing the eukaryotic algae for improved carbon removal and biomass production.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C07K 14/195 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria

Abstract

The disclosure relates to compositions and methods for reducing free asparagine concentration in the grain of wheat plants. The compositions comprise wheat plants, plant parts, plant cells, and seeds comprising a loss-of-function mutation in at least one endogenous ASPARAGINE SYNTHETASE 2 (ASN2) gene. The grain of wheat plants has reduced acrylamide-forming potential. Low acrylamide products produced from the grain are also provided.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• A01H 6/46 - Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize
• C12N 9/22 - Ribonucleases
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae

Abstract

A power plant system is disclosed. The power plant system includes a combustor, a turbine configured to generate electricity, a carbon capture system configured to remove at least a portion of carbon-based gasses from the flue gas downstream from the combustor, and a thermal storage system including a hot storage unit configured to store heat generated at least by resistively-heated gas at a hot temperature, the hot temperature greater than ambient temperature. The power plant is configured to operate in at least a first mode for storing thermal energy in the thermal storage system and a second mode for releasing the stored thermal energy from the thermal storage system and during the second mode, heat stored in the hot storage unit is transferred to the carbon capture system.

IPC Classes  ?

• F01K 3/12 - Plants characterised by the use of steam or heat accumulators, or intermediate steam heaters, therein having two or more accumulators
• F01K 17/02 - Use of steam or condensate extracted or exhausted from steam engine plant for heating purposes, e.g. industrial, domestic
• F01K 23/10 - Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids the engine cycles being thermally coupled combustion heat from one cycle heating the fluid in another cycle with exhaust fluid of one cycle heating the fluid in another cycle
• F02C 6/04 - Gas-turbine plants providing heated or pressurised working fluid for other apparatus, e.g. without mechanical power output
• F02C 6/14 - Gas-turbine plants having means for storing energy, e.g. for meeting peak loads
• F02C 6/18 - Plural gas-turbine plantsCombinations of gas-turbine plants with other apparatusAdaptations of gas-turbine plants for special use using the waste heat of gas-turbine plants outside the plants themselves, e.g. gas-turbine power heat plants

Abstract

A power plant system is disclosed. The power plant system includes a combustor, a turbine configured to generate electricity, a carbon capture system configured to remove at least a portion of carbon-based gasses from the flue gas downstream from the combustor, and a thermal storage system including a hot storage unit configured to store heat generated at least by resistively-heated gas at a hot temperature, the hot temperature greater than ambient temperature. The power plant is configured to operate in at least a first mode for storing thermal energy in the thermal storage system and a second mode for releasing the stored thermal energy from the thermal storage system and during the second mode, heat stored in the hot storage unit is transferred to the carbon capture system.

IPC Classes  ?

• F01K 3/12 - Plants characterised by the use of steam or heat accumulators, or intermediate steam heaters, therein having two or more accumulators
• F01K 17/02 - Use of steam or condensate extracted or exhausted from steam engine plant for heating purposes, e.g. industrial, domestic
• F02C 6/04 - Gas-turbine plants providing heated or pressurised working fluid for other apparatus, e.g. without mechanical power output
• F02C 6/14 - Gas-turbine plants having means for storing energy, e.g. for meeting peak loads

Abstract

A bio-barrier for reducing combustible gas emissions from the ground into the atmosphere is disclosed. The bio-barrier includes a geocomposite layer extending laterally beneath a top surface of the ground and a first geotextile layer extending laterally beneath the top surface of the ground and positioned above the geocomposite layer. The geocomposite layer and the geotextile layer configured to laterally disperse the combustible gas through at least the geotextile layer. In addition, at least one sensor may be positioned beneath the top surface of the ground and in or above the geocomposite layer, the at least one sensor measuring a parameter indicative of the concentration or oxidation of the combustible gas beneath the top surface of the ground.

IPC Classes  ?

• B01D 53/85 - Biological processes with gas-solid contact
• B01D 53/72 - Organic compounds not provided for in groups , e.g. hydrocarbons

Abstract

Inflammatory bowel disease (IBD) in humans and dogs and other companion animals is characterized by infiltration of lymphocytes and macrophages into the mucosa and submucosa and clinical signs of gastrointestinal (Gl) dysfunction (diarrhea, malabsorption, weight loss). Alteration of the gut environment and development of dysbiosis may allow the overgrowth of pathogenic bacteria and induction of intestinal injury and inflammation in IBD. What is needed are novel methods that allow for rapid diagnosis of IBD (and follow-up monitoring) and treatment of the disease. The present disclosure relates to methods for diagnosing and treating inflammatory bowel disease (IBD) or gastrointestinal lymphoma.

IPC Classes  ?

• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
• A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
• C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
• C12Q 1/6813 - Hybridisation assays
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

Abstract

Electrochemical sensing devices and methods of using thereof employs a set of one or more sensor-integrated sampling wells or containers that operates with a pressure differential micro-valve to move controlled volume of sampled fluid within a controlled cell-growing environment. The differential micro-valve can be integrated into an instrumented well having one or more sensors to provide a high-throughput smart well plate platform for use in automation operation in diagnostics and drug discovery.

IPC Classes  ?

• C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
• G01N 27/416 - Systems
• C12M 1/26 - Inoculator or sampler
• C12M 1/00 - Apparatus for enzymology or microbiology

Abstract

A method may include receiving video data that includes frames representative of infrared radiation within a scene. Each of the frames may include pixels The method may also include identifying pixels within the frames that correspond to a gas plume released by a gas source within the scene based on the infrared radiation. In addition, the method may include determining a size of the gas plume within each frame based on the identified pixels.

IPC Classes  ?

• G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis

Abstract

A method may include receiving video data that includes frames representative of infrared radiation within a scene. Each of the frames may include pixels The method may also include identifying pixels within the frames that correspond to a gas plume released by a gas source within the scene based on the infrared radiation. In addition, the method may include determining a size of the gas plume within each frame based on the identified pixels.

IPC Classes  ?

• G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
• G01J 5/00 - Radiation pyrometry, e.g. infrared or optical thermometry

Abstract

A system may include a computer-readable storage media configured to store instructions. The system may also include one or more processors communicatively coupled to the one or more computer-readable storage media. The one or more processors may be configured to, in response to execution of the instructions, cause the system to perform operations. The operations may include measuring a pressure of a volume while a user wears a mask and breathes. The volume may be defined by an interior surface of the mask and a face of the user. The operations may also include determining a differential pressure due to the mask. The differential pressure may be equal to a difference between the pressure of the volume and an ambient pressure of an environment proximate an exterior surface of the mask. In addition, the operations may include determining a mask leakage rate of the mask based on the differential pressure.

IPC Classes  ?

• G01M 3/26 - Investigating fluid tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors
• A62B 27/00 - Methods or devices for testing respiratory or breathing apparatus